Self-Supervised Time Series Representation Learning
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Engineering Digital Twins and Prognostics and Health Management (PHM) systems rely on robust perception modules to extract actionable information from heterogeneous and non-stationary time-series data. However, most existing approaches remain task-specific, data-hungry, and difficult to integrate into scalable monitoring and decision-making pipelines. Moreover, purely data-driven models often lack robustness and transferability across varying operating conditions. To address these challenges, this paper proposes a modular foundation model for time-series perception based on a collection of pretrained representation encoders. The framework leverages self-supervised learning on heterogeneous datasets to learn transferable and task-agnostic representations, which can be reused across multiple PHM tasks. A gating mechanism is introduced to dynamically select relevant encoders for a given target dataset, enabling conditional computation and adaptive model composition. The selected representations are projected into a shared latent space and aggregated using a Transformer-based self-attention module that explicitly models cross-encoder interactions. The resulting architecture supports multiple downstream tasks, including imputation, long-term forecasting, and few-shot learning, through lightweight task-specific heads, while keeping pretrained encoders frozen during adaptation. Extensive ablation studies demonstrate the complementary roles of self-supervised pretraining, encoder selection, representation alignment, and adaptive aggregation. Experimental results on the ETT benchmark show competitive performance across tasks, while a real-world industrial case study on virtual sensing for hydro-generator rotor temperature highlights the practical relevance of the approach.
Hierarchical Self-Supervised Representation Learning Framework for Multivariate Time Series Grounded in ECG Analysis
Data analysis in the medical domain often encounters scenarios involving a limited target dataset and a large, unannotated dataset with a general distribution. Under such circumstances, self-supervised learning (SSL) methods are highly effective for utilizing large datasets, making them a popular choice for electrocardiogram (ECG) analysis. This work presents the Event Reconstruction Joint-Embedding Predictive Architecture (ER-JEPA), a lightweight SSL framework for multivariate time series, whose name and two-fold hierarchical structure are inspired by the diagnostic approach of cardiologists. At its core, ER-JEPA features: (1) a two-stage structure that constructs representations for each time interval and subsequently processes these representations as a univariate time series, (2) the hierarchical integration of two Joint-Embedding Predictive Architectures (JEPAs), and (3) a Vision Transformer (ViT) backbone. The structural concatenation of two JEPAs categorizes the model as a Hierarchical JEPA (H-JEPA), designed to encode multiple levels of abstract representations for enhanced prediction on complex tasks. This study reports a successful application of H-JEPA to 12-lead ECG data as a multivariate time series, alongside an analysis of the sensitivity of hierarchical representation during the pretraining stage. Pretrained on approximately 180,000 10-second recordings, the model achieves state-of-the-art downstream performance on the ST-MEM benchmark, with rapid computation and minimal resource usage.
LeNEPA: No-Augmentation Next-Latent Prediction for Time-Series Representation Learning
Time series are central to modern data mining applications, from industrial telemetry and server metrics to finance and physiology, yet time-series self-supervised learning often depends on view and augmentation choices that encode domain-specific invariances. We study how an SSL recipe behaves when its method-specific configuration is reused unchanged after the pretraining signal family changes, framing this as a fixed-recipe stress test rather than a comparison against optimally tuned methods. We introduce Latent Euclidean Next-Embedding Prediction Architecture (LeNEPA), a no-augmentation next-latent-token objective with a causal backbone. LeNEPA replaces the stop-gradient/EMA stabilization used by vanilla NEPA with SIGReg-based isotropy regularization and computes the predictive loss in a lightweight projected space that is discarded for evaluation. We compare LeNEPA with an ECG-tuned JEPA recipe under a fixed-horizon frozen-probe protocol on PTB-XL and Diag, a synthetic diagnostic corpus generated with Aionoscope. Both methods are retrained independently on each dataset while keeping their method-specific recipes unchanged. In this protocol, the ECG-tuned JEPA recipe is strong in-domain on PTB-XL but weaker when reused unchanged on Diag, whereas LeNEPA preserves useful frozen-probe gains on both datasets. Learning curves suggest faster early representation acquisition: LeNEPA reaches 80% of its final AUROC/AUPRC gain after 2--5k updates, compared with 5--10k updates for the faster JEPA readout. As a separate external frozen-encoder check, a CauKer-pretrained LeNEPA variant reaches 77.65% mean UCR-128 Random-Forest accuracy in a single-seed, best-checkpoint run, within 1.16 points of Mantis and within 0.24 points of MOMENT (77.89%). Overall, the results support no-augmentation latent prediction as a useful candidate recipe for low-retuning time-series SSL.
Improving Patient Subtyping on Longitudinal Data using Representations from Mamba-based Architecture
Effective sub-typing (also known as grouping or clustering) of patients using their electronic health record (EHR) data can greatly inform precision medicine efforts. However, subtyping temporal EHR datasets is known to be challenging due to inherent EHR issues, including complexity and irregularity. In this study, we propose a self-supervised Mamba-based model that learns effective EHR representations and enables enhanced patient subtyping. We evaluate the proposed model on public and private real-world EHR datasets to classify the data based on the available labels and subtype patients based on the representations learned from the model. Through an extensive set of experiments, we demonstrate that our model's design choices lead to better performance compared to competitive baseline models for prediction. Moreover, we evaluate several clustering techniques to demonstrate that our findings offer valuable insights into subtyping patients based on temporal records from EHR models\footnote{Our implementations are available at https://github.com/healthylaife/triplet_mamba.
Domain-Informed Multi-View Self-Distillation for Astronomical Light-Curve Representation Learning with JEPA
Light curves describe temporal variations in the brightness of celestial objects. Learning robust representations of light curves is essential for large-scale automatic discovery in the dynamic universe, but existing time-series foundation models often struggle with the uneven sampling, complex noise, and wide range of physical timescales that characterize astronomical observations. We propose a domain-informed representation learning framework for irregular astronomical time series with Joint-Embedding predictive architecture (JEPA), combining semantics-preserving views, uncertainty-aware tokenization, and multi-view self-distillation. The encoders are trained with multi-view self-distillation using LeJEPA regularization on the LEAVES dataset and evaluated on the StarEmbed classification benchmark. On StarEmbed, our model outperforms hand-crafted features on 15 of 16 classification metrics. In few-shot linear probing, it achieves macro-F1 scores of 42.56 7.21 with one sample per class and 63.58 1.20 with 100 samples per class, consistently improving over hand-crafted features. Beyond variable-star classification, the learned representation supports similarity search, parameter estimation, and photometric zero-point drift detection. We further evaluate cross-domain adaptation on 12 heterogeneous irregular time-series datasets from PYRREGULAR, where the adapted variant matches or exceeds previous state-of-the-art performance on 5 datasets, compared with at most 3 wins by any single prior baseline. These results demonstrate that domain-informed multi-view self-distillation is an effective strategy for learning representations of irregular time series, while also highlighting that successful time-series representation learning requires domain-specific inductive biases rather than a universally optimal architecture.
SPOTR: Spatio-temporal Pooling One-Token Reconstruction for Universal Physiological Signal Self-supervised Learning
Physiological signals such as EEG, ECG, and PPG are widely used in clinical monitoring. Recent self-supervised learning (SSL) methods offer an attractive way to leverage unlabeled recordings, yet they still fall short in practice. In particular, current SSL methods struggle across heterogeneous datasets, often distorting clinically meaningful structures or learning shortcuts from temporal and cross-channel redundancy. Consequently, existing SSL methods often deliver limited performance under linear probing, a lightweight adaptation setting that better matches real-world medical scenarios. Moreover, most Transformer-based SSL models encode a flattened spatiotemporal token sequence, incurring high computation and memory cost, and are typically developed within a single modality. To address these limitations, we present SPOTR (Spatio-temporal Pooling One-Token Reconstruction), a compress-reconstruct pretraining framework that introduces a single-token global bottleneck for physiological signals. SPOTR compresses each waveform into a single-token representation and reconstructs the signal conditioned only on this representation. Meanwhile, SPOTR introduces an efficient spatio-temporal compaction module to reduce computation and memory cost. Pretrained on 20 datasets spanning EEG, iEEG, ECG, and PPG, SPOTR consistently outperforms the strongest baseline under linear probing, improving average AUC by 18.49%, 21.71%, 17.86%, and 4.64%, respectively. Compared with a representative general-purpose time-series foundation model, SPOTR achieves around 78% lower latency and 52% lower peak GPU memory on average. The code can be found at https://github.com/5GYYYYY/SPOTR.
Learning by Shifting: Temporal View Construction for Time Series Contrastive Learning
Supervised learning demands large quantities of labeled data, a bottleneck that is expensive and reliant on domain-specific expertise. Self-supervised learning, particularly contrastive learning, has emerged as a compelling alternative, enabling rich representation learning directly from unlabeled data. Yet its success hinges critically on the design of positive and negative sample pairs. Existing approaches for time series rely on hand-crafted augmentations and masking heuristics that embed strong domain assumptions, often limiting generalization across diverse temporal patterns and potentially introducing spurious correlations. In this work, we challenge this paradigm by demonstrating that explicitly encoding temporal shift invariance through a simple, deterministic view construction is sufficient to learn strong representations for time series classification. By exploiting temporal structure, our method, Shift Invariant Feature Training (ShiFT), achieves state-of-the-art performance on six diverse real-world time series benchmark datasets, as well as the UCR and UEA archives, while reducing training time. Beyond empirical performance, we present a systematic analysis of contrastive learning dynamics in time series settings, examining the effects of batch size and the number of negatives on downstream performance. Our findings provide practical insights for designing efficient contrastive learning frameworks for time series representation learning. The source code is publicly available at https://github.com/sfi-norwai/ShiFT.
PaAno+: Multiscale Encoding and Cross-Variable Attention for Time Series Anomaly Detection
Time-series anomaly detection has significant practical value for industrial and medical monitoring, as well as other critical domains. Current Transformer- and large-model-based detection approaches incur excessive computational overhead, while existing lightweight alternatives are constrained by insufficient feature extraction and inadequate modeling of dependencies across multivariate variables. To mitigate the above drawbacks, this study develops a lightweight, efficient anomaly detection model, dubbed PaAno, within the patch-oriented representation learning paradigm. In the encoder module, a multiscale feature-extraction backbone is constructed using convolutional kernels with differentiated receptive fields to capture hierarchical temporal characteristics; subsequent cross-scale adaptive attention aggregation, combined with residual connection optimization, further stabilizes feature representation learning. A cross-variable fusion attention module is embedded to explicitly characterize inter-variable correlations, empowering the model to identify anomalous patterns amid intricate operational conditions. Moreover, a novel pretext task based on temporal patch-window sorting is customized to uncover intrinsic structural properties of time series, and triplet loss is leveraged to optimize the patch embedding space for enhanced feature discrimination. Extensive experiments on the TSB-AD benchmark demonstrate that the proposed PaAno achieves state-of-the-art detection accuracy on both univariate and multivariate tasks, yielding significant performance gains across evaluation metrics, including VUS-PR, relative to the original PaAno. Leveraging a compact network design, the presented model achieves favorable computational efficiency, enabling deployment on resource-limited terminals for real-time anomaly inference.
SL-S4Wave: Self-Supervised Learning of Physiological Waveforms with Structured State Space Models
Modeling long-sequence medical time series data, such as electrocardiograms (ECG), poses significant challenges due to high sampling rates, multichannel signal complexity, inherent noise, and limited labeled data. While recent self-supervised learning (SSL) methods, based on various encoder architectures such as convolutional neural networks, have been proposed to learn representations from unlabeled data, they often fall short in capturing long-range dependencies and noise-invariant features. Structured state space models (S4) excel at long-sequence modeling, but existing S4 architectures fail to capture the unique characteristics of multichannel physiological waveforms. In this work, we propose SL-S4Wave, a self-supervised learning framework that combines contrastive learning with a tailored encoder built on structured state space models. The encoder incorporates multi-layer global convolution using multiscale subkernels, enabling the capture of both fine-grained local patterns and long-range temporal dependencies in noisy, high-resolution multichannel waveforms. Extensive experiments on real-world datasets demonstrate that SL-S4Wave (1) consistently outperforms state-of-the-art supervised and self-supervised baselines in a challenging arrhythmia detection task, (2) achieves high performance with significantly fewer labeled examples, showcasing strong label efficiency, and (3) maintains robust performance on long waveform segments, highlighting its capacity to model complex temporal dynamics in long sequences that most existing approaches fail to efficiently model, and (4) transfers effectively to unseen arrhythmia types, underscoring its robust cross-domain generalization. We additionally evaluate SL-S4Wave on multiple EEG tasks, achieving superior performance over strong baselines, demonstrating generalizability of our approach beyond cardiac waveforms.
MoCo-AIS: A Contrastive Learning Framework for Similarity Computation of Vessel Trajectories
Trajectory similarity is a fundamental task in analyzing mobility patterns, essential for applications such as route pattern extraction, mobility prediction, and anomaly detection. Traditional distance-based measures for computing similarity incur high computational cost, driving the adoption of lightweight learning-based approaches. Supervised methods rely on extensive labels derived from traditional distance measures and often reproduce these metrics, which limits generalization. While self-supervised learning addresses this issue through contrastive learning, it lacks a unified framework, making it difficult to compare deep learning (DL) models for consistent trajectory representation. Accordingly, this paper presents MoCo-AIS, a unified framework for learning vessel trajectory embeddings based on the Momentum Contrast (MoCo) paradigm, which formulates similarity learning through positive and negative trajectory pairs. Within this framework, we evaluate a diverse set of leading DL models on large-scale, real-world vessel-tracking AIS datasets that capture diverse navigation behaviors and operating conditions. Results demonstrate that our framework significantly improves similarity learning over existing baselines, while providing a benchmarking platform for evaluating trajectory representation models.
Autonomous End-to-End SOH Prediction Services for Battery Systems via Temporal-Contrastive Representation Learning
Accurate state of health (SOH) estimation is a critical diagnostic service for lithium-ion battery management. However, reliance on labor-intensive manual feature engineering and opaque black-box models hinders scalable industrial deployment. To address this, we introduce TC-SOH: a modular, plug-and-play service architecture for autonomous, end-to-end SOH prediction. TC-SOH employs a temporal-contrastive mechanism and a cross-window prediction pretext task to extract degradation-relevant representations directly from raw operational data. To improve transparency, we connect model efficacy with representation diagnostics: visualization, sensitivity analysis, redundancy analysis, bidirectional probing, future-SOH probing, and temporal shuffling show that learned features overlap with selected expert descriptors while retaining additional SOH-relevant variation, and that ordered temporal context improves subsequent-SOH prediction. Across four public datasets, TC-SOH outperforms the considered physics-informed and data-driven baselines, reducing MAPE by 1.91 times and RMSE by 2.13 times.
RECTOR: Masked Region-Channel-Temporal Modeling for Affective and Cognitive Representation Learning
Affective and cognitive disorders manifest as distributed, time-varying brain network dynamics across regions, channels, and time, challenging robust representation learning from EEG/sEEG for clinical diagnosis. We propose RECTOR (Masked Region-Channel-Temporal Modeling), an end-to-end self-supervised framework that unifies joint region-channel-temporal representation learning beyond fixed anatomical priors. At its core, RECTOR-SA is a hierarchical, block-sparse self-attention induced by Adaptive Functional Partitioning that evolves region structures from static anatomical definitions to adaptive functional regions. The self-supervision is driven by Masked Topology and Representation Learning, which jointly optimizes three complementary objectives: Masked Predictive Modeling, Topological Structure Modeling, and Cross-View Consistency. Across diverse benchmarks, RECTOR sets a new state-of-the-art in EEG emotion recognition and sEEG task-engagement classification. Crucially, its strong robustness to missing channels and cross-montage generalization underscores its potential for large-scale pre-training on heterogeneous EEG/sEEG, providing interpretable insights at both region and channel levels.
ProtoX-AD: Self-Explainable Time Series Anomaly Detection and Characterization
Recent advances in time series anomaly detection (TSAD) have highlighted the effectiveness of self-supervised classification-based approaches. These methods apply transformations to normal training samples, training a classifier to recognize transformation-specific patterns that help identify anomalies through increased classification errors. Despite their strong performance, a significant challenge is their lack of explainability, as they provide limited insight into the characteristics of flagged anomalies. To address this limitation, we propose ProtoX-AD, a prototype-based self-explainable framework for self-supervised TSAD. ProtoX-AD learns transformation-aware latent representations alongside interpretable prototypes, enabling both accurate anomaly detection and the identification of distinct anomalous profiles through prototype-based explanations. Additionally, it allows for systematic analysis of how transformation design impacts detection performance and explainability. Experimental results on synthetic and real-world datasets demonstrate that ProtoX-AD achieves detection performance comparable to its black-box counterparts while offering more consistent and semantically meaningful explanations than existing explainable baselines. Our code is publicly available at https://github.com/Aitorzan3/ProtoX-AD.
Next-Token Prediction Learns Generalisable Representations of Sleep Physiology
Foundation models offer a promising route to compress multi-modal physiological signals into compact representations of human health, with broad applications across sleep medicine, cardiology, neurology and other healthcare domains. Existing models have typically been trained with masked-reconstruction or contrastive objectives. However, masked reconstruction may be poorly suited to the stochastic nature of these signals, while contrastive approaches rely on positive-pair definitions despite the semantic invariances of physiological signals being poorly understood. In this work, we show that next-token prediction is a simple and scalable alternative. We develop Hypnos, a multi-modal sleep foundation model trained using eight different sensing modalities (e.g. EEG, ECG, respiratory signals) drawn from over 20,000 overnight polysomnography recordings. We tokenize each modality into streams of discrete tokens using residual vector quantization, then train a large auto-regressive RQ-Transformer to jointly predict the next token across all modalities in parallel. After training, Hypnos can be applied to continuous streams of sensor data from any subset of supported modalities, generating embeddings for downstream tasks. Across a range of benchmarks, Hypnos significantly outperforms existing foundation models. In sleep stage classification, we match the performance of strong supervised baselines on held-out test sets whilst using less labelled data. Hypnos even generalises to daytime physiology, surpassing a dedicated ECG foundation model at detecting atrial fibrillation. Our results demonstrate that next-token prediction is a strong self-supervised objective for representation learning from multi-modal physiological signals.
GNSS-FM: A Self-Supervised Foundation Model for Daily GNSS Displacement Time Series
Displacement time series from Global Navigation Satellite Systems (GNSS) are essential for a wide range of applications, including monitoring tectonic crustal deformations and investigating the different stages of the earthquake cycle. Machine learning methods have proven promising for GNSS applications; however, most remain fully supervised. This creates a bottleneck as labeled data are scarce, even though large amounts of unlabeled GNSS data are freely available. We present GNSS-FM, a self-supervised foundation model for daily GNSS time series. The model uses a dual-stream input combining displacement and velocity-like increments, and is pretrained using a masked latent prediction objective with vector-quantized targets adapted from wav2vec 2.0, with several modifications for geodetic data. Pretrained on data from over 17,000 globally distributed GNSS stations, an analysis of the learned codebook suggests that the representations capture the main signal types in GNSS displacement data, including seismic offsets, tectonic drift, and seasonal patterns. The foundation model is later fine-tuned on two downstream tasks, namely 90-day displacement forecasting and seismic step localization, where it outperforms strong task-specific baselines in both cases. These results show that self-supervised pretraining is a promising approach for GNSS time series analysis.
CF-JEPA: Mask-free forward prediction with asymmetric encoder utilization for time-series representation learning
Self-supervised learning (SSL) for time-series representation learning is dominated by two paradigms: contrastive methods, which face challenges in constructing positive or negative pairs, and masking-based methods, which disrupt the temporal continuity of time-series signals. Joint-Embedding Predictive Architecture (JEPA) offers a promising alternative by predicting in representation space rather than reconstructing raw inputs. However, existing time-series JEPA variants still rely on masking and therefore inherit its continuity problem. Crop-based Forward JEPA (CF-JEPA) is proposed as an innovative mask-free framework that replaces masking with multi-horizon forward prediction: random crops serve as context views, and short-, mid-, and long-horizon future representations are predicted in the forward temporal direction, directly leveraging the inherent temporal ordering of time-series data as a learning signal. A strong asymmetry is also identified between the online encoder and the exponential moving average (EMA) target encoder, both produced from a single training run: the online encoder develops higher-rank discriminative features, while the EMA target encoder develops smoother, lower-rank temporal features. Exploiting this asymmetry, classification is routed to the online encoder and forecasting or anomaly detection to the EMA target encoder, achieving a 27% reduction in multivariate forecasting mean squared error (MSE) at no additional training cost. Across 126 University of California, Riverside (UCR) and 26 University of East Anglia (UEA) classification datasets, eight electricity transformer temperature forecasting benchmarks, and Key Performance Indicator /Yahoo anomaly detection, CF-JEPA achieves the highest average accuracy and rank on UCR and UEA among self-supervised baselines and ranks second on univariate forecasting and k-nearest neighbors-scored anomaly detection.
T-SAR-JEPA: Self-Supervised Temporal Anomaly Detection in SAR Amplitude Stacks via Latent Prediction
We present T-SAR-JEPA, a self-supervised framework for temporal anomaly detection in SAR amplitude stacks via latent prediction. A ViT-Base/16 encoder from SAR-JEPA is domain-adapted on 39,300 Capella patches using local masked reconstruction with gradient feature prediction. A temporal transformer with sinusoidal time encoding forecasts future latent states from K=7 acquisitions, with progressive unfreezing substantially reducing validation loss. The model operates on amplitude alone; InSAR coherence serves exclusively as independent pseudo-ground-truth. On the DFC 2026 dataset (300 time-series, three AOIs), T-SAR-JEPA achieves ROC-AUC of 77.0% on the Hawaii eruption window, outperforming RX, PaDiM, Linear AR, and LSTM baselines (~50%). Spatial coherence of 99.9% (p < 0.001, permutation test) confirms structured detections. Code: https://github.com/TerraLatent/t-sar-jepa
Learning Cardiac Latent Representations in Vectorcardiogram Space
Electrocardiography (ECG) is a cornerstone of cardiac assessment, making the learning of informative ECG representations fundamental to tasks ranging from disease diagnosis to clinical report generation. However, existing methods operate almost exclusively in the observable ECG signal space. In practice, the standard twelve-lead ECG represents multiple projections of the same underlying cardiac electrical activity from different spatial orientations. Therefore, representation learning in the ECG space inevitably introduces substantial redundancy, which may lead to spurious correlations and increased risk of overfitting. To address this and motivated by the Frank vectorcardiogram (VCG) model, we propose learning a unified latent representation of cardiac electrical activity directly in the VCG space. We introduce LVCG, the first general self-supervised representation learning framework designed to operate in this physically grounded latent space. By learning view-invariant latent VCG representations rather than lead-specific artifacts, VCG minimizes redundancy and improves generalization. LVCG generally outperforms ECG-space baselines across tasks, demonstrating enhanced robustness and generalization, especially in domain shift settings.
STEP: Learning STructured Embeddings for Progressive Time Series
We present a novel method for learning interpretable representations of progressive time series, that is, data capturing irreversible state transitions such as degradation or task completion. Our approach uses a self-supervised contrastive objective to learn a low-dimensional latent space whose geometry is itself the interpretation: each observation becomes a point on a manifold anchored between two fixed orthogonal prototype vectors, and a trajectory becomes a path across that manifold. From this structure we read a latent compass, the polar coordinates (θ, r) of the latent vector, in which θ tracks the progression of the underlying state (e.g., from healthy to failed) and r identifies the active mode (e.g., the operating condition), without any proxy labels. We evaluate the approach against the state of the art on diverse domains, including industrial degradation, robotic tasks, and neural activity, validating three key capabilities: (1) end-state prediction, (2) multi-step forecasting, and (3) interpretable phase separation. Our method matches or improves over black-box counterparts on all of these while providing transparency about the underlying mechanisms. A simple linear regressor on top of the latent compass coordinates is competitive with deep architectures, direct quantitative evidence that the underlying state is encoded in a geometrically accessible form.
FHRFormer: A Self-Supervised Masked Transformer Framework for Fetal Heart Rate Time-Series Inpainting and Forecasting
Approximately 10% of newborns require assistance to initiate breathing at birth, and around 5% need ventilation support. Fetal heart rate (FHR) monitoring plays a crucial role in assessing fetal well-being during prenatal care, enabling the detection of abnormal patterns and supporting timely obstetric interventions to mitigate fetal risks during labor. Applying artificial intelligence (AI) methods to analyze large datasets of continuous FHR monitoring episodes with diverse outcomes may offer novel insights into predicting the risk of needing breathing assistance or interventions. Recent advances in wearable FHR monitors have enabled continuous fetal monitoring without compromising maternal mobility. However, sensor displacement during maternal movement, as well as changes in fetal or maternal position, often lead to signal dropout, resulting in gaps in recorded FHR data. Such missing data limits the extraction of meaningful insights and complicates automated (AI-based) analysis. Traditional approaches to handling missing data, such as simple interpolation techniques, often fail to preserve the spectral characteristics of the signals. In this paper, we propose a masked transformer-based autoencoder approach to reconstruct missing FHR signals by capturing both local temporal and frequency components of the data. The proposed method demonstrates robustness across varying durations of missing data and can be used for signal inpainting and forecasting. The proposed approach can be applied retrospectively to research datasets to support the development of AI-based risk algorithms. In the future, the proposed method could be integrated into wearable FHR monitoring devices to achieve earlier and more robust risk detection.
CaMBRAIN: Real-time, Continuous EEG Inference with Causal State Space Models
Electroencephalography (EEG) is a critical, non-invasive method to monitor electrical brain activity. EEGs can span anywhere from a couple seconds to multiple hours, posing a major hurdle for existing deep learning methods due to two major factors: (1) existing EEG models are predominantly built upon the attention mechanism, incurring quadratic scaling as the sequence length increases, and (2) raw EEG signals must be processed in a sliding-window fashion due to fixed-length input requirements, preventing global understanding of the entire signal. To this extent, we propose CaMBRAIN - the first Causal, Mamba-based state space model (SSM) capable of real-time inference of EEG signals, arguing that bidirectional approaches are needlessly expensive given the causal, unidirectional nature of EEG. However, training such a model is non-trivial, as crucial EEG events can be extremely brief - within fractions of a second - yet separated by long intervals spanning minutes. Current EEG methods use self-supervised objectives that optimize for signal reconstruction, but these are not well suited for streaming SSMs; they fail to explicitly train the hidden state to retain the salient long-range context needed for streaming inference. We therefore introduce a multi-stage self-supervised training pipeline specifically tailored to encourage long-range memory retention and strong performance on EEG signals, while preserving the linear-time complexity of state space models. CaMBRAIN achieves state-of-the-art (SOTA) results across 3 different EEG datasets with >10x higher throughput than existing models, enabling the first model capable of long-range, continuous inference of variable-length EEG signals.
Information-theoretic Multimodal Representation Learning for Electrocardiogram Signals
Electrocardiograms (ECGs) are widely used non-invasive measurements of cardiac activity and play a central role in clinical diagnosis. Recent multimodal approaches align ECG signals with clinical reports to incorporate diagnostic semantics, but clinical reports often fail to preserve the rich physiological structure of ECG waveforms, particularly across multiple levels of abstraction ranging from coarse diagnostic categories to fine-grained morphology. To address this limitation, we formulate ECG representation learning from an information-theoretic perspective and derive a tractable objective that jointly preserves signal structure and integrates clinical semantics. Based on this principle, we propose \textbf{MERIT} (Multimodal ECG Representation via Information Theory), a dual-branch pretraining framework combining masked ECG modeling with ECG--text contrastive alignment. Extensive experiments on PTB-XL and additional benchmarks demonstrate consistent improvements over prior methods, including gains exceeding F1 on PTB-XL All and F1 on SubClass classification. In zero-shot evaluation, MERIT further improves performance by up to AUC and F1 on PTB-XL SubClass, while also demonstrating robustness under multiple distribution-shift settings. Moreover, leveraging the learned ECG representations for ECG-conditioned clinical text generation with large language models improves text quality across several metrics, including ROUGE and METEOR. Together, these results demonstrate that MERIT learns more informative and clinically meaningful ECG representations, particularly for fine-grained clinical applications.
Aperiodic and Low-Frequency Spectral Bias in Reconstruction based EEG Foundation Models
EEG foundation models, pre-trained on large-scale unlabelled EEG data, have emerged as a promising direction towards learning generalizable EEG representations. Despite showing positive results in data-rich regimes, they often fail to outperform significantly smaller supervised models in low-resource settings compared to fully supervised models. We provide a mechanistic account of this shortcoming, attributing it to a fundamental mismatch between reconstruction-based pretext tasks and the idiosyncratic spectral structure of EEG signals, which decompose into distinct high-power aperiodic and low-power oscillatory components. Using controlled, synthetically-generated EEG inputs, we demonstrate that EEG foundation model embeddings are biased to capture the aperiodic components of the EEG signal while under-representing oscillatory components, particularly at higher frequencies. Additionally, linear probe evaluations on real-world BCI datasets further reveal that embeddings encode subject identity more strongly than task-relevant information, thereby reinforcing the low-frequency and aperiodic component bias in foundation model embeddings trained primarily on reconstruction based objectives. Together, these findings elucidate a failure mode in reconstruction based EEG foundation models and motivate future work to incorporate auxiliary losses explicitly targeting high-frequency oscillatory structure as a path toward more capable and generalizable EEG representations.
Sleep-stage efficient classification using a lightweight self-supervised model
Accurate classification of sleep stages is crucial for diagnosing sleep disorders and automating this process can significantly enhance clinical assessments. This study aims to explore the use of a self-supervised model (more specifically, an adapted version of mulEEG) combined with a Linear SVM classifier to improve sleep stage classification. \textbf{Methods:} The mulEEG model, which learns electroencephalogram signal representations in a self-supervised manner, was simplified here by replacing ResNet-50 with 1D-convolutions used as time series encoder by a ResNet-18 backbone. Two other adaptations were conducted: the first one evaluated different configurations of the model and data volume for training, while the second tested the effectiveness of time series features, spectrogram features, and their concatenation as inputs to a Linear SVM classifier. \textbf{Results:} The results showed that reducing the volume of data offered a better cost-benefit ratio compared to simplifying the model. Using the concatenated features with ResNet-18 also outperformed the linear evaluations of the original mulEEG model, achieving higher classification performance. \textbf{Conclusions:} Simplifying the mulEEG model to extract features and pairing it with a robust classifier leads to more efficient and accurate sleep stage classification. This approach holds promise for improving clinical sleep assessments and can be extended to other biological signal classification tasks.
On the Role of Inductive Bias in Time-Series Pretraining: A Case Study in Learning Generalizable Representations for Clinical Time Series
Clinical time-series learning is routinely constrained by small, heterogeneous cohorts and protocol drift, while its downstream use spans both classification (e.g., pathology diagnosis) and regression (e.g., temporal forecasting). These constraints make foundation-model pretraining appealing, but raises an important question of which inductive biases should the pretraining objective impose so that representations transfer across task types and subjects. We study this question in pathological gait analysis for spinal cord injury (SCI) via PathoFM, an encoder-centric transformer pretrained on multivariate gait windows with three complementary objectives: Local Completion (reconstruct contiguous masked spans to enforce local structure), Temporal Continuity (predict a masked mid-horizon continuation from an observed prefix to enforce smoothness and causal consistency), and Unsupervised In-Context Dynamics (support-query reconstruction conditioned on subject exemplar windows via attention). Empirically comparing objective families (grouping/contrastive, dynamics-based, and generative reconstruction), we find that dynamics-centric mixtures produce the most balanced transfer: grouping objectives favor discriminative margins but can degrade magnitude fidelity needed for continuous targets, whereas reconstruction-only objectives preserve waveform structure but may underperform on classification. Overall, combining local reconstruction with temporal continuity, and adding in-context conditioning when exemplar access is realistic, yields robust subject-generalizing representations.
VACE: Learning Geometrically Structured Representations for Time Series Anomaly Detection
Anomaly detection in multivariate time series is a critical task across a wide range of real-world applications, where abnormal behaviour is rare, labels are unavailable, and the cost of a miss is high. The central challenge is learning a characterisation of normality precise enough to flag deviations. Representation self-supervised learning, typically through contrastive approaches, addresses this by embedding temporal patches into a latent space where normality occupies a well-defined region, with anomalies detected by geometric deviation. However, contrastive approaches shape this space indirectly through pair-sampling heuristics, providing no explicit control over the geometric structure that distance-based scoring requires. This means how tightly normal representations are grouped, and whether distances are directionally meaningful. We present VACE (Velocity-Aligned Channel Embeddings), a self-supervised anomaly detection method that represents normality as a compact, directionally coherent region in the embedding space. To this end, VACE trains a channel-aware encoder through a velocity-consistency objective, with no negatives and no synthetic anomalies, so that normal trajectories are locally smooth and aligned. At test time, a Mahalanobis positional score and a velocity-bank directional score are combined multiplicatively, flagging points that are simultaneously off-distribution and dynamically atypical. Despite its simplicity, VACE achieves state-of-the-art performance on TSB-AD-M under rigorous evaluation, significantly outperforming more complex methods trained on substantially larger budgets.
CALAD: Channel-Aware contrastive Learning for multivariate time series Anomaly Detection
Multivariate time series anomaly detection has become increasingly important in real-world applications, where labeled data are often scarce. Many existing approaches rely on unsupervised learning to model normal patterns, but they often treat all channels equally. This design can dilute anomaly-relevant signals, since not all channels contribute equally to anomaly detection. In this paper, we propose CALAD, a channel-aware contrastive learning framework for multivariate time series anomaly detection. CALAD governs the construction of contrastive samples using estimated channel relevance, allowing the learning process to reflect anomaly semantics rather than generic similarity. Channel relevance is estimated from reconstruction errors of a transformer-based autoencoder and is used to distinguish channels that are more influential to anomalous behaviors. Using this information, we design a channel-wise augmentation strategy in which positive and negative samples are constructed based on whether anomaly-relevant channels are preserved or perturbed. This encourages invariance to changes in irrelevant channels while being sensitive to changes in anomaly-relevant channels. Furthermore, CALAD combines contrastive learning and an auxiliary reconstruction head, allowing the model to learn discriminative representations while retaining normal structures. Experiments on multiple real-world datasets shows that CALAD consistently outperforms existing methods, particularly under distribution shift scenarios. We provide the code for reproducibility at https://github.com/hirundo1218/CALAD
ChronoVAE-HOPE: Beyond Attention -- A Next-Generation VAE Foundation Model for Specialized Time Series Classification
Time Series Foundation Models (TSFMs) have become a new component of the state-of-the-art in general time series forecasting. However, adapting them to specialized classification tasks remains constrained by two interconnected challenges: the quadratic cost of standard attention mechanisms and the inability to disentangle the structural components underlying time series variability. This technical report introduces ChronoVAE-HOPE, a next-generation TSFM that reconciles massive generalization with structured latent representation for time series classification. The core of the proposal is a Variational Autoencoder (VAE) framework built upon the HOPE Block, which replaces quadratic attention with a dual-memory system: Titans modules for dynamic short-term retention and a Continuum Memory System (CMS) for the abstraction of long-term historical context. A key architectural novelty is the disentangled latent space, which factorizes representations into independent trend and seasonal components via dedicated encoder heads and separate decoder pathways. ChronoVAE-HOPE undergoes self-supervised pre-training on the Monash archive, combining a Masked Time Series Modeling (MTSM) auxiliary objective with a disentangled VAE reconstruction loss. The pre-trained encoder is subsequently frozen and used to generate fixed-length embeddings for downstream classification on the UCR benchmark datasets. Empirical results demonstrate strong performance across diverse temporal domains, particularly in settings characterized by strict causal structure. ChronoVAE-HOPE establishes a robust and interpretable framework for the adaptation of foundation models to time series classification through structured generative representations.
Divide and Contrast: Learning Robust Temporal Features without Augmentation
Self-supervised learning for time-series representation aims to reduce reliance on labeled data while maintaining strong downstream performance, yet many existing approaches incur high computational costs or rely on assumptions that do not hold across diverse temporal dynamics. In this work, we introduce Divide and Contrast (Di-COT), an unsupervised framework that avoids data augmentation and multiple encoder passes by contrasting informative substructures within a window rather than individual timesteps. Di-COT stochastically partitions each window into a small number of overlapping sub-blocks per iteration, enabling efficient and meaningful contrast while mitigating false positives during temporal transitions. To further improve scalability, we adopt a contrastive objective whose computation depends on the batch size and the number of sub-blocks, making loss computation independent of sequence length. Extensive experiments on six large-scale real-world datasets, as well as the UCR and UEA benchmarks, demonstrate that Di-COT learns semantically structured and transferable representations, achieving state-of-the-art performance on classification, clustering, NN, and cross-dataset transfer, while substantially reducing training time. The source code is publicly available at https://github.com/sfi-norwai/Di-COT.
PACD-Net: Pseudo-Augmented Contrastive Distillation for Glycemic Control Estimation from SMBG
Effective diabetes management requires continuous monitoring of glycemic levels. Clinically, glycemic control is assessed using metrics such as Time in Range (TIR), Time Below Range (TBR), and Time Above Range (TAR), typically derived from continuous glucose monitoring (CGM). However, many patients rely on self-monitoring of blood glucose (SMBG) due to the high cost and limited accessibility of CGM. Unlike CGM, SMBG provides sparse and irregular measurements, making accurate estimation of these metrics challenging. Conventional supervised learning approaches struggle under such sparsity, leading to poor generalization and unstable performance. To address this, we propose PACD-Net, a self-supervised contrastive knowledge distillation framework for estimating glycemic control from SMBG. Pseudo-SMBG samples with richer temporal coverage are used as teacher signals to guide learning from sparse observations. In addition, multi-view contrastive learning enforces representation consistency across diverse sampling patterns. The model adopts a hybrid Swin Transformer-CNN backbone to capture temporal dependencies in sparse SMBG sequences. Experimental results demonstrate that PACD-Net consistently outperforms existing methods in estimating TAR, TIR, and TBR from real-world SMBG data, achieving improved accuracy as well as enhanced stability and generalization under extremely sparse observation settings. The proposed framework provides a practical tool for clinical SMBG interpretation and offers a generalizable approach for learning from sparse and irregularly sampled sensor data in broader applications.