Longitudinal EHR Modeling

EHR: Electronic Health Record

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16 papers in the last four weeks, up 433% on the four weeks before. 0.2% of all new papers.

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  1. SepsisLens: Structure-Preserving Sequence Modelling for Decomposable Early Sepsis Warning

    Oct 6, 2026Yikun Ou, Wei LiInterpretable MLClinical Prediction

    School of Computer Science, University of Sydney Sydney, Australia

  2. HyperNSDE: Personalized Neural SDEs for Joint Static-Longitudinal Clinical Data Generation

    Oct 5, 2026Perrine Chassat, Agathe GuillouxStochastic Differential EquationsSynthetic Data Generation

    Inria, Université Paris Cité, Inserm, HeKA F-75015 Paris, France

  3. Auditable Clinical Timeline Reconstruction with Provenance-Aware Evidence Graphs

    Oct 5, 2026Judith Jeyafreeda AndrewData ProvenanceClinical QA

    Public Health Unit, Medical Information Department, Bordeaux University Hospital (CHU Bordeaux), Bordeaux, France.

  4. LifeLong Digital Twin: A Unified Modeling Paradigm and Agent Harness for Event-Driven Lifelong Health State Trajectories

    Oct 4, 2026Jin Jiang, Sean Yates, Jasper Chong +4Clinical PredictionDigital Twins

    Peking University · VITA-Med Group

  5. Bridging the EHR Divide: Asymmetric Contrastive Learning for Cross-National Medical Representation Transfer

    Oct 4, 2026Qingyang ZhangCross-Domain Transfer LearningLongitudinal EHR Modeling

    Information Networking Institute Carnegie Mellon University Pittsburgh, United States

  6. GLoC-EHR: Evidence-Cited Clinical Reasoning over Global Context and Local EHR Events

    Oct 1, 2026Chaiho Shin, Kwangsoo KimEvidence-Grounded ReasoningClinical Outcome Prediction

    Interdisciplinary Program of Medical Informatics, Seoul National University College of Medicine · Department of Transdisciplinary Medicine, Seoul National University Hospital · Center for Data Science, Healthcare AI Research Institute, Seoul National University Hospital +1

  7. OverdoseMoE: A Multi-Expert Framework for Opioid Overdose Risk Prediction

    Sep 30, 2026Mingchen Li, Rohan Pandey, Junhui Qian +3Mixture of ExpertsLongitudinal EHR Modeling

    Manning College of Information and Computer Sciences, UMass Amherst, Amherst, MA, USA · Center for Healthcare Organization and Implementation Research, VA Bedford Health Care, Bedford, MA, USA · Miner School of Computer and Information Sciences, UMass Lowell, Lowell, MA, USA

  8. CAMOS: Coupled Oscillatory State-Space Model for Multimodal Clinical Time-Series

    Sep 30, 2026Maxx Richard Rahman, Mostafa Hammouda, Wolfgang MaassIrregular Time-Series ModelingMissing-Modality Learning

    Saarland University and German Research Center for Artificial Intelligence (DFKI) Saarbrücken, Germany · Saarland University Saarbrücken, Germany

  9. Personalized State-Transition-Aware Memory for Clinical Agents

    Sep 29, 2026Maryam Haghifam, Zahra Rajabi, Yizhou Sun +1LLM Agent MemoryState Tracking

    Department of Computer Science, University of California, Los Angeles, CA, USA · Optum AI, UnitedHealth Group, Minneapolis, MN, USA

  10. ReLMem: Learning Recurrent Memory for Longitudinal EHR Modeling

    Sep 29, 2026Zijie Meng, Xiwei Dai, Yingying Zhang +3Memory-Augmented Language ModelsClinical Prediction

    Zhejiang University · Tencent Jarvis Lab

  11. Admissible Diffusion for Multimodal Interventional Trajectories

    Sep 28, 2026Xing Han, Shravan Chaudhari, Jiarui Shao +2Constrained Generative ModelingCausal Inference

    Johns Hopkins University · Massachusetts Institute of Technology · Bayesian Health

  12. EHRAdapt: Adapting Pretrained Language Models to Electronic Health Records with Semantic Priors for Rare Clinical Events

    Sep 27, 2026Andre R Goncalves, Vincent Liu, Priyadip RayLong-Tail LearningAdapter Tuning

    Lawrence Livermore National Laboratory · Kaiser Permanente

  13. Pretrained Medical Representations for the Practical Screening of Drug Repositioning Candidates

    Sep 17, 2026Yuhei Fujioka, Daitaro Misawa, Shingo FukumaRepresentation LearningHierarchical Representation Learning

    Cancerscan Inc., Tokyo, Japan · Kyoto University, Graduate School of Medicine, Kyoto, Japan · Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima, Japan

  14. CliniCIRCA: A Modular LLM Framework for Constructing Longitudinal Mental Health Patient Journeys from Raw EHR Narratives

    Sep 17, 2026Aiwei Ivy Zhang, Nimra Ishfaq, Mohit Chandra +5Temporal Reasoning in Language ModelsMental Health

    Georgia Institute of Technology · University of Texas at Austin · Northwell Health

  15. EviGen: Predictive Evidence Scaffolding for Verifiable Clinical Rationale Generation

    Sep 16, 2026Fengnan Li, Heman Burre, Liwen Sun +2LLM Answer VerificationClinical Outcome Prediction

    Duke University

  16. Rethinking How We Evaluate Methodological Progress in Health AI

    Sep 16, 2026Florent Pollet, Matthew McDermottML ReproducibilityLongitudinal EHR Modeling

    Department of Biomedical Informatics, Columbia University

  17. Anchoring Clinical Events in Time: UID-Preserving Multimodal Reconstruction and Source-Grounded Adjudication

    Sep 14, 2026Sayantan Kumar, Nicolas Grimaldi, Jack Cummins +1Multimodal GroundingDocument Information Extraction

    National Library of Medicine, National Institutes of Health, USA · Princeton University, USA

  18. Reinforcement Learning over Patient Trajectories for Clinical Reasoning in EHR Foundation Models

    Sep 14, 2026Yuxin Xiao, Sheng Zhang, Chandan Singh +4Reinforcement LearningClinical Outcome Prediction

    MIT · Microsoft Research

  19. NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

    Sep 8, 2026Tobias Susetzky, Raphael Rehms, Dmitrii Seletkov +5Irregular Time-Series ModelingClinical Prediction

    Chair for AI in Healthcare and Medicine, TUM University Hospital and Technical University of Munich (TUM), Munich, Germany · Institute for Diagnostic and Interventional Radiology, TUM University Hospital, Munich, Germany · Munich Center for Machine Learning (MCML), Munich, Germany +3

  20. Import What You Need: Learning When and How to Augment EHR Graphs with External Knowledge

    Sep 1, 2026Chen Chen, Mohsen Nayebi Kerdabadi, Dongjie Wang +2Graph Structure LearningLongitudinal EHR Modeling

    Electrical Engineering and Computer Science, University of Kansas, USA · Health Outcomes and Biomedical Informatics, University of Florida, USA

  21. Random Hazard Forests

    Aug 21, 2026Hemant Ishwaran, Eileen M. Hsich, Udaya B. Kogalur +1Irregular Time-Series ModelingSurvival Analysis

    Division of Biostatistics, Department of Public Health Sciences, Miller School of Medicine, University of Miami · Heart and Vascular Institute, Cleveland Clinic; Cardiology Division, Intermountain Health · Kogalur & Company, Inc. +1

  22. Intervention-Aware Clinical World Model for Post-Op Outcome Forecasting in Cardiology

    Aug 13, 2026Yunsung Chung, Yingshuo Liu, Abboud F. Hassan +4Irregular Time-Series ModelingClinical Outcome Prediction

    Tulane University, New Orleans, LA 70118, USA · Simula Research Laboratory, Oslo, Norway

  23. QuanTiMedAI: Quantum-Enhanced Time-Series Model guided by Agentic AI for Cardiac Arrest Mortality Prediction

    Aug 6, 2026Mutasim Fuad Sarker, Adiba Rahman Namira, Wafa Binte Alam +3Hybrid Quantum-Classical MLLongitudinal EHR Modeling

    Dept. of ECE North South University, Dhaka, Bangladesh · Dept. of ECE Memorial University, St. John’s, NL, Canada

  24. MiGHT-EHR: A Multi-task Graph Transformer for Heterogeneous Temporal Electronic Health Records

    Aug 5, 2026Anirudh Rayas, Yuan Wang, Pavan TuragaHeterogeneous GNNsClinical Decision Support

    Arizona State University, Tempe, AZ, USA · University of South Carolina, Columbia, SC, USA

  25. Patients-like-me: A Variational LM--GNN Framework for Explainable Clinical Prediction

    Aug 4, 2026Xinyu Wang, Yixuan Li, Hanwei Wu +4Graph Neural NetworksClinical Outcome Prediction

    1McGill University · 2Université de Montréal · 3Georgia State University +1

  26. Federated generative event models for tokenized electronic health records

    Aug 3, 2026Michael C. Burkhart, Luke Solo, Inhyeok Lee +8Clinical Outcome PredictionGenerative Modeling

    Department of Medicine, University of Chicago, Chicago, Illinois, USA · Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

  27. CT-HEG: A Bidirectional, Timestamp-Attributed Event Graph for ICU In-Hospital Mortality Prediction - An Architectural Ablation Study

    Aug 1, 2026Mohammad Nasir Uddin, Rahnuma Tabassum Orpita, Asaduzzaman Anik +4Heterogeneous GNNsLongitudinal EHR Modeling

    College of Business, DBA-BIDA, Westcliff University, Los Angeles, CA, USA · Dept. of CSE, Northern University Bangladesh, Dhaka, Bangladesh · MBA, Business Administration & Management, Stanton University, Anaheim, CA, USA +2

  28. DRIFT: Direct-Recursive Intervention-Conditioned Forecasting of ICU Physiological Trajectories

    Jul 28, 2026Weixin Liu, Juming Xiong, Congning Ni +4Multivariate Time Series ForecastingTime Series Forecasting

    Vanderbilt University, Nashville, Tennessee, USA · Vanderbilt University Medical Center, Nashville, Tennessee, USA

  29. Contrastive Representation Learning of Longitudinal Disease Trajectories on Temporal Graphs

    Jul 28, 2026Bastian PfeiferTemporal GNNsGraph Contrastive Learning

    Institute for Medical Informatics, Statistics and Documentation · Medical University Graz · Graz, Austria

  30. Medical world models in healthcare: foundations, applications, and challenges for trustworthy clinical translation

    Jul 28, 2026Zhaoyan Chen, Zhongxiu Cong, Zhuanfeng Jin +7World Model LearningLongitudinal EHR Modeling

    National and Local Joint Engineering Laboratory of Computer Aided Design, School of Software Engineering, Dalian University, Dalian, China · Department of Radiology, Xinhua Hospital Affiliated to Dalian University, Dalian, China · The Chinese University of Hong Kong, Shenzhen, China +3

  31. Autoregressive EHR Foundation Models with Multimodal Inputs

    Jul 24, 2026Yuxuan Liu, Joshua Placidi, Jinpei Han +3Clinical Outcome PredictionMultimodal Token Compression

    Dept. of Computing, Imperial College London, London, United Kingdom · UKRI Centres in AI for Health, United Kingdom · School of Public Health, Imperial College London, London, United Kingdom +2

  32. Pretraining EHR Foundation Models with Patient-Aware Sampling

    Jul 24, 2026Joshua Placidi, Yuxuan Liu, Jinpei Han +2Longitudinal EHR ModelingElectronic Health Records

    Dept. of Computing, Imperial College London, London, United Kingdom · Dept. of Bioengineering, Imperial College London, London, United Kingdom · UKRI Centres in AI for Health, United Kingdom +1

  33. MissHyper: Restoring Clinical Synchronicity in Missingness-Guided Hypergraph Forecasting

    Jul 24, 2026Mingyi Ma, Qingxiong TanIrregular Time-Series ModelingMultivariate Time Series Forecasting

    Academy of Advanced Interdisciplinary Studies Wuhan University · Institute for Mathematics & Artificial Intelligence Wuhan University

  34. Biological Amnesia in ICU Time-Series Prediction: A Drift-Adaptive Two-Stream Architecture with Temporal Retrieval

    Jul 21, 2026Fatema Ferdous Tamanna, K. M. Merajul Arefin, Md. Abdul MasudClinical Decision SupportLongitudinal EHR Modeling

    Dept. of Computer Science and Information Technology, Patuakhali Science and Technology University, Bangladesh · Dept. of Computer Science and Engineering, University of Dhaka, Bangladesh

  35. A Framework for Early Sepsis Prediction via Self-Supervised (JEPA) and Federated Representation Learning

    Jul 18, 2026Umair bin Mansoor, Munaf Rashid, Roomi NaqviSelf-Supervised Pre-TrainingJoint-Embedding Predictive Architecture

    Electrical Engg. Department, DHA Suffa University, Karachi, Pakistan · Salim Habib University, Karachi, Sindh, Pakistan · Intel Foundry Services, Intel, Tempe, Arizona, United States

  36. TEDDY: A Pediatric Foundation Model for Risk Forewarning from ICD-Coded Diagnostic Histories

    Jul 15, 2026Matthew Brady Neeley, Jorge Botas, Johnathan Jia +5Clinical PredictionLongitudinal EHR Modeling

    Baylor College of Medicine

  37. AdaPCLA: Adaptive Prior-Calibrated Logit Adjustment for Long-Tailed Longitudinal EHR Generation

    Jul 14, 2026Shuai Cui, Chen Wenxuan, Wenjie Du +3Long-Tail LearningSynthetic Data Generation

    University of Science and Technology of China · Sun Yat-sen University

  38. Evidence-Grounded AI for Musculoskeletal Care

    Jul 14, 2026Wenjie Li, Yujie Zhang, Fanrui Zhang +34HealthcareClinical Decision Support

    Department of Orthopaedics, Ruijin Hospital, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China · Shanghai Innovation Institute, Shanghai, China · Shanghai Artificial Intelligence Laboratory, Shanghai, China +7

  39. Multimodal Routing for Interpretable, Robust, and Auditable Clinical Prediction

    Jul 10, 2026Nikkie Hooman, Zhongjie Wu, Eric C. Larson +1Multimodal RobustnessClinical Prediction

    Southern Methodist University Dallas, USA

  40. LongMedBench: Benchmarking Medical Agents for Long-Horizon Clinical Decision-Making

    Jul 10, 2026Zihan Xu, Yanzhen Chen, Xiaocheng Zhang +4Long-Horizon Agent EvaluationClinical Decision-Making

    Zhejiang University, Hangzhou, China · Alibaba Group, Hangzhou, China · Transvascular Implantation Devices Research Institute, Hangzhou, China

  41. X-FEMR: A Token-level Explainable Approach for Electronic Health Records Foundation Models using Transformer-based Models

    Jul 7, 2026Jie Huang, Pengfei Yin, Zihan Xu +3Neural Surrogate ModelingNeural Network Interpretability

    School of Computing and Information Systems, University of Melbourne, Melbourne, Australia · Department of General Medicine, Royal Melbourne Hospital Melbourne, Australia

  42. Teaching LLMs to Recommend and Defer in Underrepresented Epilepsy Care

    Jun 30, 2026Shreyas Rajesh, Kartik Sharma, Tonmoy Monsoor +8Prompt LearningSelective Prediction

    Electrical and Computer Engineering, University of California, Los Angeles · Makerere University · St. Francis Hospital Nsambya +1

  43. ENC-ODE: Event-level Neurodegenerative Modeling in Continuous Time with Neural ODEs

    Jun 29, 2026Yujee Song, Seunghun Baek, Guorong Wu +1Latent Dynamics ModelingLongitudinal EHR Modeling

    Pohang University of Science and Technology, Pohang, South Korea · University of North Carolina at Chapel Hill, Chapel Hill, USA

  44. The Verbose Context Problem in Medical Records

    Jun 28, 2026Shiva Kaul, Min-Gyu Kim, Anjum Khurshid +1Long-Context ModelingLongitudinal EHR Modeling

    Department of Population Medicine · Department of Biomedical Informatics, Ajou University School of Medicine · Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School +1

  45. Improving Patient Subtyping on Longitudinal Data using Representations from Mamba-based Architecture

    Jun 26, 2026Md Mozaharul Mottalib, Rahmatollah BeheshtiMambaSelf-Supervised Time Series Representation Learning

    University of Delaware, Newark, Delaware, USA

  46. PORTER: Language-Grounded Event Representations for Portable Structured EHR Foundation Models

    Jun 23, 2026Lin Lawrence Guo, Adam Paul Yan, Emily Vettese +1Clinical Outcome PredictionText Embedding Models

    Child Health Evaluative Sciences · The Hospital for Sick Children · Toronto, Canada +1

  47. VISTA Architect: A graph database-oriented health AI system demonstrated in multidisciplinary tumor boards

    Jun 21, 2026Tuomo Kiiskinen, Jason Fries, Philip Adamson +7HealthcareClinical Decision Support

    Department of Biomedical Data Science, Stanford University School of Medicine · Department of Medicine, Stanford University School of Medicine

  48. Cohort-Anchored Foundation Models for Electronic Health Records: From Risk Scores to Auditable Peer Cohorts

    Jun 20, 2026Kaiping ZhengClinical Decision-MakingMultimodal Model Interpretability

    National University of Singapore

  49. MedRLM: Recursive Multimodal Health Intelligence for Long-Context Clinical Reasoning, Sensor-Guided Screening, Evidence-Grounded Decision Support, and Community-to-Tertiary Referral Optimization

    Jun 18, 2026Aueaphum AueawatthanaphisutClinical Decision SupportMultimodal Reasoning

    School of Information, Computer, and Communication Technology Sirindhorn International Institute of Technology, Thammasat University Pathum Thani, Thailand

  50. Routine laboratory trajectories encode the onset of organ-level complications in cancer

    Jun 7, 2026Jannik Lübberstedt, Krischan Braitsch, Jacqueline Lammert +21Toxicity DetectionOncology

    Department of Diagnostic and Interventional Radiology, School of Medicine and Health, TUM Klinikum, Rechts der Isar, Technical University of Munich, Germany. · Department of Medicine III, School of Medicine and Health, TUM Klinikum, Rechts der Isar, Technical University of Munich, Germany. · Chair of Medical Informatics, Institute of Artificial Intelligence in Medicine and Healthcare, School of Medicine and Health, TUM Klinikum, Rechts der Isar, Technical University of Munich, Germany. +8

  51. LongMoE: Longitudinal Multimodal Learning via Trajectory-Aware Mixture-of-Experts

    Jun 6, 2026Maxx Richard Rahman, Prakhar Kumar, Wolfgang MaassMissing-Modality LearningMultimodal Robustness

    German Research Centre for Artificial Intelligence (DFKI) Saarbrücken, Germany

  52. Accelerating Reproducible Research in Synthetic EHR Generation

    Jun 5, 2026Jalen Jiang, Chufan Gao, Ethan Rasmussen +2Synthetic Data GenerationML Reproducibility

    University of Illinois Urbana-Champaign

  53. A Machine Learning-Based Framework for Discovering Huntington's Disease Stages: Integrating Graph Representation Learning and clustering to Uncover Progression Dynamics in Longitudinal Enroll-HD Dataset

    Jun 4, 2026Lubna M. Abu Zohair, Marta Vallejo, MD Azher Uddin +2Unsupervised ClusteringLongitudinal EHR Modeling

    School of Mathematical and Computer Sciences, Heriot-Watt University, Dubai, United Arab Emirates · School of Mathematical and Computer Sciences, Heriot-Watt University, Edinburgh, United Kingdom

  54. HoT-SSM:Higher-order Temporal Knowledge Graph Reasoning with State Space Models for Health Care

    Jun 4, 2026Thummaluru Siddartha Reddy, Vempalli Naga Sai Saketh, Yash Punjabi +1Clinical Outcome PredictionHypergraph Neural Networks

    Fujitsu Research of India, Bangalore

  55. Causal Longitudinal Prior-Fitted Networks for Counterfactual Outcome Prediction

    Jun 4, 2026Amirhossein Zare, Amirhessam Zare, Herlock Rahimi +2Structural Causal ModelsCounterfactual Prediction

    School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. · Department of Electrical and Computer Engineering, Yale University, New Haven, CT, USA. · School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. +2

  56. Modeling and Interpreting Teamwork Dynamics in Cancer Care Outcome Prediction

    Jun 3, 2026Yuhua Huang, Hsiao-Ying Lu, Kwan-Liu MaCancer Survival PredictionHealthcare

    University of California, Davis Davis, California, USA

  57. Traj-Evolve: A Self-Evolving Multi-Agent System for Patient Trajectory Modeling in Lung Cancer Early Detection

    Jun 1, 2026Sihang Zeng, Matthew Thompson, Ruth Etzioni +1Retrieval-Augmented GenerationMedical Diagnosis

    University of Washington · Fred Hutch Cancer Center · Google

  58. ChatHealthAI: Aligning Electronic Health Record Representations with Large Language Models for Grounded Clinical Reasoning

    Jun 1, 2026Bo-Hong Wang, Baicheng Peng, Ruilin Wang +3LLM GroundingLLM Alignment

    School of Computer Science, McGill University, Montreal, QC, Canada · Mila - Quebec AI Institute, Montreal, QC, Canada

  59. Scalable Counterfactual Risk Estimation for Rare Events in Longitudinal Data

    Jun 1, 2026Xiaohui Yin, Avijit Mitra, Ying Zhou +2Causal Effect EstimationSurvival Analysis

    University of Massachusetts Amherst Amherst, Massachusetts, USA · University of Massachusetts Lowell Lowell, Massachusetts, USA

  60. Digitally enriching a high-risk population for pancreatic cancer using routine blood-based measures and clinical histories

    May 28, 2026Chris Varghese, Leo Y. Li-Han, Richa Bisht +10OncologyLongitudinal EHR Modeling

    Department of Surgery, Mayo Clinic, Rochester, MN, USA · Department of Surgery, University of Auckland, Auckland, NZ · Department of Hematology and Oncology, Mayo Clinic, Phoenix, AZ, USA +5