Multi-Modal Large Language Models

Despite remarkable capability in multi-modal understanding, deploying Multi-modal Large Language Models (MLLMs) in open-ended conversational scenarios introduces safety risks that remain poorly addressed by existing alignment methods. Unlike simple malicious visual question and answer (VQA) pairs , multi-turn interactions enable adversaries to incrementally reconstruct harmful intent across dialogues, progressively bypassing safety constraints in ways that are difficult to detect at any individual turn. Meanwhile, conventional reinforcement learning from human feedback (RLHF) approaches are unsuitable for this situation: designed primarily for VQA tasks, they neither capture cross-turn risk dynamics nor scale efficiently without costly manual preference annotation. To close this gap, we introduce \textbf{MINT-Safe}, an open-source visual multi-turn training dataset comprising 11,270 multi-image dialogues and 500 refusal VQA pairs, constructed via multi-agent interaction with text-to-image (T2I) tool-call augmentation. Building on MINT-Safe, we propose \textbf{TAD-Align}, a dialogue safety alignment framework centered on a turn-aware dual-objective reward function. Rather than treating all dialogue turns uniformly, TAD-Align leverages rollout-based safety score variance to dynamically identify turns where the model exhibits inconsistent safety behavior, and adaptively up-weights these turns during optimization. Experiments on Qwen2.5-VL-7B-Instruct and LLaVA-NeXT-7B demonstrate reductions of over 10% in Attack Success Rate (ASR), alongside improvements of at least 8% in harmlessness and 13% in helpfulness on multi-modal multi-turn safety benchmarks, while preserving general model capabilities.

Disclaimer: Samples in this paper may be harmful and cause discomfort. Multimodal large language models (MLLMs) enable multimodal understanding but inherit toxic signals from weakly curated pretraining corpora, leading to explicitly toxic outputs, especially under adversarial triggers that late, opaque training-free detoxification methods struggle to handle. We propose SGM, a white-box neuron-level multimodal intervention that acts like safety glasses for toxic neurons: it recalibrates a set of toxicity-associated neurons via expertise-weighted soft suppression, neutralizing harmful cross-modal activations without any parameter updates. We establish MM-TOXIC-QA, a multimodal toxicity data framework, and compare SGM with existing detoxification techniques. Experiments on open-source MLLMs show that SGM mitigates explicit toxicity in standard and adversarial conditions, cutting average harmful rates from 45.0% to 4.5% while preserving fluency and multimodal reasoning. SGM is extensible, and its combined defenses, denoted as SGM*, integrate with existing detoxification methods for stronger safety performance, providing an interpretable, low-cost solution for toxicity-controlled multimodal generation.

Multimodal large language models (MLLMs) can inadvertently memorize privacy-sensitive information during training. While existing unlearning methods can remove such content, they often severely degrade the model's foundational capabilities, such as general image understanding. This critical shortfall motivates our investigation into benign memory forgetting, the precise removal of targeted, privacy-sensitive knowledge while rigorously preserving unrelated capabilities. To pioneer and evaluate progress toward this objective, we introduce S-MLLMUn Bench, the first benchmark designed to jointly and quantitatively assess an unlearning method's efficacy in knowledge erasure and the preservation of image understanding. Furthermore, we propose the Sculpted Memory Forgetting Adapter (SMFA), a new framework that enables benign memory forgetting. SMFA confines forgetting to designated memory regions, maintaining overall model performance. By initially fine-tuning the model to replace sensitive outputs with refusals, SMFA generates a memory forgetting adapter, followed by a retaining anchor-guided masking mechanism that safeguards unrelated knowledge. Extensive experiments on S-MLLMUn Bench demonstrate that existing methods fail to achieve benign forgetting, whereas our proposed SMFA serves as an effective baseline, successfully achieving targeted knowledge erasure without compromising the model's foundational visual capabilities. Code and data are available at https://github.com/zeng-zhen/S-MLLMUn.

Discrete diffusion-based multimodal large language models (dMLLMs) have emerged as a promising alternative to autoregressive MLLMs thanks to their advantages in parallel decoding and bidirectional context modeling, but most existing dMLLMs incur significant computational overhead during inference due to the full-sequence attention computation in each denoising step. Pioneering studies attempt to resolve this issue from a modality-agnostic perspective via key-value cache optimization or efficient sampling but most of them overlook modality-specific visual token redundancy. In this work, we conduct a comprehensive study on how visual token redundancy evolves with different dMLLM architectures and tasks and how visual token pruning affects dMLLM responses and efficiency. Specifically, our study reveals that visual redundancy emerges only in from-scratch dMLLMs while handling long-answer tasks. In addition, we validate that visual token pruning introduces non-negligible information loss in dMLLMs and only from-scratch dMLLMs can recover the lost information progressively during late denoising steps. Furthermore, our study shows that layer-skipping is promising for accelerating AR-to-diffusion dMLLMs, whereas progressive or late-step pruning is more effective for from-scratch dMLLMs. Overall, this work offers a new perspective on efficiency optimization for dMLLMs, greatly advancing their applicability across various multimodal understanding tasks. The code is available at: https://github.com/Yrdal3910/dMLLM-Visual-Token-Redundancy-Analysis.

Large Language Models (LLMs) with multimodal capabilities have revolutionized vision-language tasks, but their deployment often requires huge memory and computational resources. Post-training quantization (PTQ) has successfully compressed language models to as low as 1-bit precision, its effectiveness for multimodal LLMs (MLLMs) remains unexplored. In this paper, we present the first method for ultra-low-bit (<4-bit) quantization of MLLMs. Our analysis reveals that multimodal tokens and intermediate layer activations produced by them exhibit significantly higher entropy compared to text tokens, indicating greater functional complexity that makes MLLMs less tolerant to ultra-low bit quantization. However, this entropy varies significantly across layers, with some layers producing lower-entropy activation distributions that we empirically show can better tolerate ultra-low bit quantization. Existing PTQ methods optimize weight quantization within each layer but apply the same target precision uniformly, ignoring this variation in complexity across layers. Building on this insight, we propose LUQ: Layerwise Ultra-Low Bit Quantization, which characterizes each transformer layer's functional complexity via its output activation entropy and selectively applies ultra-low bit quantization to layers encoding simpler, more compressible functions. We also show that multimodal calibration (image and text tokens) boosts VQA performance in the ultra-low bit regime. Evaluated on LLaVA-1.5 and Qwen-2.5-VL across 9 VQA benchmarks, LUQ models use 40% and 31% less memory than their 4-bit counterparts while exhibiting less than 10% degradation on MME.

The rapid advancement of large language models (LLMs) has intensified the need for effective mechanisms to transform continuous multimodal data into discrete representations suitable for language-based processing. Discrete tokenization, with vector quantization (VQ) as a central approach, offers both computational efficiency and compatibility with LLM architectures. Despite its growing importance, there is a lack of a comprehensive survey that systematically examines VQ techniques in the context of LLM-based systems. This work fills this gap by presenting the first structured taxonomy and analysis of discrete tokenization methods designed for LLMs. We categorize 8 representative VQ variants that span classical and modern paradigms and analyze their algorithmic principles, training dynamics, and integration challenges with LLM pipelines. Beyond algorithm-level investigation, we discuss existing research in terms of classical applications without LLMs, LLM-based single-modality systems, and LLM-based multimodal systems, highlighting how quantization strategies influence alignment, reasoning, and generation performance. In addition, we identify key challenges including codebook collapse, unstable gradient estimation, and modality-specific encoding constraints. Finally, we discuss emerging research directions such as dynamic and task-adaptive quantization, unified tokenization frameworks, and biologically inspired codebook learning. This survey bridges the gap between traditional vector quantization and modern LLM applications, serving as a foundational reference for the development of efficient and generalizable multimodal systems. A continuously updated version is available at: https://github.com/jindongli-Ai/LLM-Discrete-Tokenization-Survey.

Current CT report generation frameworks predominantly rely on global feature representations, often failing to capture region-specific details and potentially missing certain abnormalities. To overcome this limitation, we propose MedRegion-CT, a region-focused multimodal large language model framework featuring three key innovations. First, we revisit the SlowFast strategy to jointly model global and fine-grained information and adapt it to the medical domain via a Region-based SlowFast Tokenizer that extracts tokens guided by clinically meaningful regions. Second, generated pseudo-masks guide the model to attend to diagnostically important anatomical regions, facilitating a systematic understanding of the overall scan context. Third, quantitative lesion information, including size, diameter, and spatial location, is encoded as structured textual prompts, enabling context-aware and clinically informed report generation. To enable rigorous evaluation, we validate our framework on multi-institutional structured report generation benchmarks. Experimental results demonstrate that MedRegion-CT achieves state-of-the-art performance, outperforming existing approaches in both linguistic quality and clinical accuracy. All code is publicly available at: https://github.com/babbu3682/MedRegion-CT.

Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in understanding common visual elements, largely due to their large-scale datasets and advanced training strategies. However, their effectiveness in medical applications remains limited due to the inherent discrepancies between data and tasks in medical scenarios and those in the general domain. Concretely, existing medical MLLMs face the following critical limitations: (1) limited coverage of medical knowledge beyond imaging, (2) heightened susceptibility to hallucinations due to suboptimal data curation processes, (3) lack of reasoning capabilities tailored for complex medical scenarios. To address these challenges, we first propose a comprehensive data curation procedure that (1) efficiently acquires rich medical knowledge data not only from medical imaging but also from extensive medical texts and general-domain data; and (2) synthesizes accurate medical captions, visual question answering (VQA), and reasoning samples. As a result, we build a multimodal dataset enriched with extensive medical knowledge. Building on the curated data, we introduce our medical-specialized MLLM: Lingshu. Lingshu undergoes multi-stage training to embed medical expertise and enhance its task-solving capabilities progressively. Besides, we preliminarily explore the potential of applying reinforcement learning with verifiable rewards paradigm to enhance Lingshu's medical reasoning ability. Additionally, we develop MedEvalKit, a unified evaluation framework that consolidates leading multimodal and textual medical benchmarks for standardized, fair, and efficient model assessment. We evaluate the performance of Lingshu on three fundamental medical tasks, multimodal QA, text-based QA, and medical report generation. The results show that Lingshu consistently outperforms the existing open-source multimodal models on most tasks ...

In this work, we propose Dimple, the first Discrete Diffusion Multimodal Large Language Model (DMLLM). We observe that training with a purely discrete diffusion approach leads to significant training instability, suboptimal performance, and severe length bias issues. To address these challenges, we design a novel training paradigm that combines an initial autoregressive phase with a subsequent diffusion phase. This approach yields the Dimple-7B model, trained on the same dataset and using a similar training pipeline as LLaVA-NEXT. Dimple-7B ultimately surpasses LLaVA-NEXT in performance by 3.9%, demonstrating that DMLLM can achieve performance comparable to that of autoregressive models. To improve inference efficiency, we propose a decoding strategy termed confident decoding, which dynamically adjusts the number of tokens generated at each step, significantly reducing the number of generation iterations. In autoregressive models, the number of forward iterations during generation equals the response length. With confident decoding, however, the number of iterations needed by Dimple is even only $\frac{\text{response length}}{3}$. We also re-implement the prefilling technique in autoregressive models and demonstrate that it does not significantly impact performance on most benchmark evaluations, while offering a speedup of 1.5x to 7x. Additionally, we explore Dimple's capability to precisely control its response using structure priors. These priors enable structured responses in a manner distinct from instruction-based or chain-of-thought prompting, and allow fine-grained control over response format and length, which is difficult to achieve in autoregressive models. Overall, this work validates the feasibility and advantages of DMLLM and enhances its inference efficiency and controllability. Code and models are available at https://github.com/yu-rp/Dimple.

The steady improvements of text-to-image (T2I) generative models lead to slow deprecation of automatic evaluation benchmarks that rely on static datasets, motivating researchers to seek alternative ways to evaluate T2I progress. We present Multimodal Text-to-Image Eval (MT2IE), an evaluation framework in which a single multimodal large language model (MLLM) acts as an evaluator agent, iteratively generating the evaluation prompts and scoring the resulting images. We show that MT2IE's image-text consistency scores have higher correlation with human judgment than metrics previously introduced in the literature. MT2IE generates prompts that are efficient at probing T2I model performance: closely recovering the official T2I model rankings of three structurally distinct benchmarks from just 20 generated evaluation prompts, 28-105x fewer than the benchmarks' own prompt sets. When compared to existing evaluation metrics such as CLIPScore, VIEScore, and VQAScore, MT2IE's T2I model rankings are more faithful and far more consistent across multiple evaluation seeds when using the same number of prompts. MT2IE can also adapt evaluation to the model being tested: rewriting each prompt based on the model's own measured performance to produce a bespoke per-model benchmark that still recovers the official rankings and keeps the evaluated model in an informative scoring range. We hope that these results will encourage the development of dynamic and interactive evaluation frameworks, and mitigate the deprecation of automatic evaluation benchmarks.

To overcome the black-box nature of predictive AI and the hallucination risks of generative models, retrieval-based models offer an interpretable, evidence-based paradigm for pathology clinical workflow. However, real-world clinical queries are inherently interleaved (e.g., pathology images and text). Current dual-encoders suffer from an \textbf{Architectural Mismatch}, lacking the mechanism to fuse such composed queries. To address this, we formalize the task of Pathology Composed Retrieval (PCR). While Multimodal Large Language Models (MLLMs) offer deep-fusion capabilities, directly applying them exposes a \textbf{Task Mismatch} and a \textbf{Domain Mismatch}. To resolve these challenges, we propose HOMIE, a model-agnostic adaptation framework that transforms any generative MLLM into a specialized pathology retrieval expert. Evaluated on our newly introduced PCR Benchmark, a lightweight 2B-parameter HOMIE variant substantially outperforms existing paradigms, surpassing specialized 7B pathology MLLMs and dual-encoders by large margins on composed retrieval, while maintaining strong performance on traditional simple retrieval. The project page is available at https://qfchou.github.io/HOMIE_page/.

Semantic role labeling (SRL) is a central natural language processing task for understanding predicate-argument structures within texts and enabling downstream applications. Despite extensive research, comprehensive surveys that critically synthesize the field from a unified perspective remain lacking. This survey makes several contributions beyond organizing existing work. We propose a unified four-dimensional taxonomy that categorizes SRL research along model architectures, syntax feature modeling, application scenarios, and multimodal extensions. We provide a critical analysis of when and why syntactic features help, identifying conditions under which syntax-aided approaches provide consistent gains over syntax-free counterparts. We offer the first systematic treatment of SRL in the era of large language models, examining the complementary roles of LLMs and specialized SRL systems and identifying directions for hybrid approaches. We extend the scope of SRL surveys to cover multimodal settings including visual, video, and speech modalities, and analyze structural differences in evaluation across these modalities. Literature was collected through systematic searches of the ACL Anthology, IEEE Xplore, the ACM Digital Library, and Google Scholar, covering publications from 2000 to 2025 and applying explicit inclusion and exclusion criteria to yield approximately 200 primary references. SRL benchmarks, evaluation metrics, and paradigm modeling approaches are discussed alongside practical applications across domains. Future research directions are analyzed, addressing the evolving role of SRL with large language models and broader NLP impact.

Large language models (LLMs) are widely applied in various fields of society due to their powerful reasoning, understanding, and generation capabilities. However, the security issues associated with these models are becoming increasingly severe. Jailbreaking attacks, as an important method for detecting vulnerabilities in LLMs, have been explored by researchers who attempt to induce these models to generate harmful content through various attack methods. Nevertheless, existing jailbreaking methods face numerous limitations, such as excessive query counts, limited coverage of jailbreak modalities, low attack success rates, and simplistic evaluation methods. To overcome these constraints, this paper proposes a multimodal jailbreaking method: JMLLM. This method integrates multiple strategies to perform comprehensive jailbreak attacks across text, visual, and auditory modalities. Additionally, we contribute a new and comprehensive dataset for multimodal jailbreaking research: TriJail, which includes jailbreak prompts for all three modalities. Experiments on the TriJail dataset and the benchmark dataset AdvBench, conducted on 13 popular LLMs, demonstrate advanced attack success rates and significant reduction in time overhead.

Previous studies on federated learning (FL) often encounter performance degradation due to data heterogeneity among different clients. In light of the recent advances in multimodal large language models (MLLMs), such as GPT-4v and LLaVA, which demonstrate their exceptional proficiency in multimodal tasks, such as image captioning and multimodal question answering. We introduce a novel federated learning framework, named Multimodal Large Language Model Assisted Federated Learning (MLLM-LLaVA-FL), which employs powerful MLLMs at the server end to address the heterogeneous and long-tailed challenges. Owing to the advanced cross-modality representation capabilities and the extensive open-vocabulary prior knowledge of MLLMs, our framework is adept at harnessing the extensive, yet previously underexploited, open-source data accessible from websites and powerful server-side computational resources. Hence, the MLLM-LLaVA-FL not only enhances the performance but also avoids increasing the risk of privacy leakage and the computational burden on local devices, distinguishing it from prior methodologies. Our framework has three key stages. Initially, we conduct global visual-text pretraining of the model. This pretraining is facilitated by utilizing the extensive open-source data available online, with the assistance of MLLMs. Subsequently, the pretrained model is distributed among various clients for local training. Finally, once the locally trained models are transmitted back to the server, a global alignment is carried out under the supervision of MLLMs to further enhance the performance. Experimental evaluations on established benchmarks, show that our framework delivers promising performance in the typical scenarios with data heterogeneity and long-tail distribution across different clients in FL.

Multimodal Large Language Models (MLLMs) suffer from cross-modal hallucinations, where one modality inappropriately influences generation about another, leading to fabricated output. This exposes a more fundamental deficiency in modality-interaction control. To address this, we propose Modality-Adaptive Decoding (MAD), a training-free method that adaptively weights modality-specific decoding branches based on task requirements. MAD leverages the model's inherent ability to self-assess modality relevance by querying which modalities are needed for each task. The extracted modality probabilities are then used to adaptively weight contrastive decoding branches, enabling the model to focus on relevant information while suppressing cross-modal interference. Extensive experiments on CMM and AVHBench demonstrate that MAD significantly reduces cross-modal hallucinations across multiple audio-visual language models (7.8% and 2.0% improvements for VideoLLaMA2-AV, 8.7% and 4.7% improvements for Qwen2.5-Omni). Our approach demonstrates that explicit modality awareness through self-assessment is crucial for robust multimodal reasoning, offering a principled extension to existing contrastive decoding methods. Our code is available at \href{https://github.com/top-yun/MAD}{https://github.com/top-yun/MAD}

Multimodal large language models (MLLM) for surgical scene understanding typically inject hundreds of dense visual tokens into a language model, leading to costly inference and limited spatial traceability for generated answers. We present Slot2Text, a dual-mode surgical MLLM that replaces dense representations of visual input with a compact set of regions encoded as slot latents. Instead of relying on contrastive alignment of the visual encoder with language, Slot2Text groups self-supervised vision features into a few regions--slots that are consumed by the language model as area-labeled visual tokens. Slot2Text-Fast uses the slot prefix to answer surgical questions. Slot2Text-Reason also identifies and locates areas relevant for reasoning, linking language outputs to corresponding slot tokens, masks or regions. Experiments on multiple visual question answering and visual grounding benchmarks show that Slot2Text-Fast is competitive with state-of-the-art baseline at a much lower cost, reducing the average total token consumption by a 91.8% and the visual prefix from 1,295 to 47 tokens (a 96.4% reduction). Slot2Text-Reason trades additional tokens and latency for explicit area identities, locations, and traceable spatial evidence. These results establish compact slot latents as an efficient default visual interface for surgical MLLMs, with grounded reasoning invoked when greater spatial traceability is required.