Weakly Supervised Semantic Segmentation

Open-vocabulary semantic segmentation (OVSS) enables pixel-level prediction over arbitrary text-specified vocabularies and has shown strong generalization on common benchmarks. However, OVSS performance often degrades in specialized domains such as medical imaging, remote sensing, and industrial inspection, where dense pixel-level masks for adaptation are costly to obtain and require domain-specific expertise. We propose a preference-guided adaptation framework that replaces dense mask supervision with binary preferences. We observe that different prompt templates produce systematically different segmentations for the same image, a phenomenon we call prompt disagreement, and we repurpose it as a built-in source of preference supervision. Building on this, we mine localized preference queries from regions of high cross-template uncertainty, and adapt the OVSS model with Region-Localized Preference Optimization (RLPO) together with consistency regularization that stabilizes updates outside the queried region. Across extensive experiments on the MESS benchmark, the proposed method achieves consistent gains across diverse OVSS backbones without any pixel-level annotation, and remains effective under noisy preferences. Our code is available at https://github.com/blue-531/pref-ovss.

Weakly Supervised Semantic Segmentation (WSSS) learns pixel-level predictions from image-level tags. Recent work focuses on improving coarse CAMs extracted from large vision-language models (commonly CLIP), but does little to improve their accuracy along segment boundaries. That job is instead delegated to a post-processing method like DenseCRF. However, because DenseCRF relies on low-level colour cues, it can flip correct labels to incorrect ones when neighbouring pixels share similar colours. SAM has recently been adopted as a natural alternative, yet it simply takes on DenseCRF's role as an intermediate "refinement" step that outputs one-hot pseudo-labels in prior work. By discarding the valuable uncertainty in CAMs, these one-hot pseudo-labels turn borderline errors into confidently wrong targets. Our key insight is that CAMs should supervise training alongside SAM boundaries, each through its own loss, rather than being fused together into a single hard target. Inspired by CRF potentials, we propose a framework that disentangles soft pseudo-labels as unary supervision and binary edge maps as pairwise supervision. We realize our framework in a single-stage model, DS-CRF, using CAMs from dino.txt and boundaries from SAM. DS-CRF sets a new state-of-the-art of 56.5% mIoU on MS COCO.

High-resolution water mapping supports environmental monitoring and related applications, but accurate pixel-level labels are difficult and costly to produce. Official hydrographic vectors provide scalable weak supervision, but they contain artifacts like boundary noise, temporal mismatch, and omissions of small water structures. We propose a two-stage framework for weakly supervised water segmentation in high resolution multispectral imagery. Stage 1 learns initial masks from rasterized vector pseudo-labels, and Stage 2 converts these masks into structured component-wise prompts for localized refinement. On a manually corrected validation set, refinement improves SegFormer-B0 from 0.9509 to 0.9535 IoU and U-Net from 0.9408 to 0.9486 IoU, with corresponding F1 gains from 0.9749 to 0.9762 and 0.9695 to 0.9736. It leads to sharper shorelines, reduced boundary spillover, and better thin-structure delineation. The results indicate that prompt-guided refinement can improve pseudo-label-based water segmentation by targeting local errors that are poorly captured by global training supervision.

In semiconductor manufacturing, defect analysis is essential, but manual inspection cannot scale. However, existing automated inspection methods remain insufficient for root-cause analysis and process optimization. To this end, we present SePArate, a weakly supervised wafer defect segmentation method. SePArate enables pixel-level separation of patterns by leveraging only image-level annotations. It consists of a three-phase training: encoder pretraining, knowledge transfer to learn spatial cues, and training on synthetic mixed-defect data for accurate segmentation. Experiments demonstrate that SePArate outperforms the baselines.

Multimodal satellite imagery provides complementary information for Earth Observation, but accurately combining heterogeneous sensors remains challenging in dynamic environments. Fast-changing regions, such as the Antarctic marginal ice zone, cannot fully exploit multimodal information from different satellite sensors because surface features move between image acquisitions. This spatial and temporal mismatch challenges effective perceptual grounding, violating the assumption of pixel-level correspondence that underpins most multimodal reasoning and downstream classification pipelines. Antarctic sea ice provides a challenging benchmark due to the rapid, heterogeneous drift of individual ice floes and the differing responses of sea ice to radar, visible and thermal sensing modalities. Accurate, dense supervision of sea ice remains scarce because generating pixel-wise labels requires time-consuming expert interpretation of noisy data, leading to historical reliance on coarse-resolution maritime ice charts for model training. This paper presents a novel architecture based on mutual information warping to align multi-satellite (Sentinel-1 and MODIS platforms) multimodal (visible, thermal, radar) satellite scenes. To demonstrate the approach, we introduce a sparse expert-labeled dataset of 2,088 pixel-wise annotations (7,046 expert point classifications) located at the ice-water margin interface across 43 scenes. Our results demonstrate that spatially grounding and aligning modalities prior to segmentation improves classification accuracy, and enables accurate, dense sea ice segmentation from sparse point-wise supervision.

Weakly supervised semantic segmentation enables histopathology tissue segmentation from image-level annotations, avoiding costly pixel-level labeling by expert pathologists. However, CAM-based methods often localize only highly discriminative regions and remain unreliable near tissue interfaces. We propose ProBAG, a stage-1 pseudo-mask generator that combines dataset-specific visual prototypes with pathology-aligned CONCH text prototypes over multi-scale frozen UNI features. ProBAG introduces two complementary mechanisms: class-wise power recalibration that reshapes inter-class competition while preserving the total foreground activation mass at each pixel, and one-step graph diffusion in which feature affinities are penalized by a late-transformer attention-context discrepancy used as a soft structural boundary cue. The resulting stage-1 pseudo-masks require neither CRF nor an external segmentation model; for complete two-stage comparison, they additionally supervise a downstream Phikon-FPN segmenter. Experiments on BCSS-WSSS and LUAD-HistoSeg show consistent gains over recent WSSS approaches, while ablations indicate that pathology-aligned text semantics provide the largest improvement and graph refinement provides a smaller complementary gain. The code is available at: https://github.com/wterrr/WSSS

Weakly supervised segmentation relies heavily on class activation maps (CAMs) to initially localize target regions. However, CAMs are often noisy and prone to catastrophic failures. Existing remedies typically introduce additional training stages or prototype learning, increasing computational cost and reducing robustness. In this paper, we propose a training-free prototype-free framework that rectifies unreliable CAMs by exploiting temporal and structural coherence in volumetric data as a free lunch. Our approach is built on two key components. First, we introduce Variance-Reduced Activation Aggregation (VRAA) which suppresses noise and amplify coherent semantic signals. We provide a theoretical justification by modeling CAMs as high-dimensional random vectors and show that aggregation yields provable variance reduction. Second, we design a Bidirectional Extremity Rectification (BER) mechanism that detects and rectifies implausible activations through bidirectional extremity checks, effectively mitigating extreme-value failures without learning additional parameters. Our method is model-agnostic and can be seamlessly integrated with existing pipelines. Extensive experiments on multiple public benchmarks demonstrate substantial improvements over state-of-the-art weakly supervised methods, achieving up to 20% Dice and 40% mIoU gains while reducing inference time by more than 5 times. These results indicate that leveraging coherence as an implicit inductive bias yields a principled and efficient approach to stabilizing weakly supervised volumetric segmentation. Our code will be available.

Whole-slide images (WSIs) provide rich tissue-level and cellular-level information, but storing and transmitting high-magnification pathology data is resource-intensive. Moreover, annotating WSIs at the pixel level is labor-intensive and time-consuming. Therefore, it is important to investigate whether low-magnification pathology images with limited annotations (i.e., image-level instead of pixel-level labels) can achieve performance comparable to high-magnification images. This paper presents a systematic benchmark study on weakly supervised histopathological image segmentation under different low-resolution storage settings. Starting from high-resolution image patches, we simulate lower-magnification inputs and reconstruct them to the original size using interpolation and deep learning-based reconstruction methods before applying the weakly-supervised segmentation pipeline. This framework enables a quantitative evaluation of how weakly supervised methods respond to different levels of resolution degradation. Experimental results show that reconstruction quality metrics alone are insufficient to predict downstream segmentation performance. In particular, the study identifies a critical degradation point where the localization of small-scale structures declines significantly. These findings provide practical guidance for designing efficient digital pathology storage systems while maintaining reliable automated analysis. Code is available at https://github.com/Dung-Dx/LowMagWSS

The precise pixel-level localization of 2D material flakes is crucial for high-throughput screening. However, traditional fully supervised methods rely on dense annotations, which are costly and time-consuming, severely limiting the practical deployment of segmentation models. This paper proposes TACoS, a specialized scribble segmentation framework tailored for 2D materials. First, we design a unified framework that integrates semi-supervised consistency learning with structured tree energy constraints. This framework comprises two core components: an unlabeled weak-strong distribution alignment module and a tree energy regularization module. The former employs cosine consistency constraints to enhance prediction alignment across views. Meanwhile, the latter utilizes minimum spanning trees to establish pixel affinity relationships and generate structure-aware soft pseudo labels for online semantic guidance. Next, we introduce asymmetric regional contrast learning. This approach fuses high-confidence predictions from the weak augmentation branch with scribbles to form augmented labels, and construct category prototypes in the representation space. Simultaneously, we prioritize contrastive constraints on challenging pixels in boundary-unlabeled regions. This strategy enhances intra-class cohesion and inter-class separation at the representation level, effectively reducing category confusion in low-contrast edges and complex backgrounds. Experiments conducted on the constructed graphene and MoS2 datasets demonstrate that our method TACoS achieves over 96% of fully supervised performance using less than 0.6% annotated data. Furthermore, it exhibits superior structural coherence and boundary stability in scenarios with weakly contrasting edges and complex backgrounds, providing an efficient and scalable solution for automated high-throughput screening of 2D material flakes.

Histopathological tissue segmentation is essential for computer-aided diagnosis, yet weakly supervised methods often suffer from noisy pseudo-labels generated by Class Activation Mapping (CAM). Existing CAM approaches tend to focus on staining-driven appearance cues rather than true causal tissue morphology, resulting in spurious localization and poor structural consistency. To address this issue, we propose C$^2$RM-Seg, a two-stage framework that integrates causal pseudo-label refinement with structure-aware semantic enhancement. For classification, we introduce a Causal Counterfactual Reasoning Module (C$^2$RM) that decomposes features into latent factors and performs counterfactual intervention via a learned causal structure matrix, suppressing confounding context and producing morphology-aligned CAMs. For segmentation, we design a Dual-Path Structural-Semantic Architecture that combines fine-grained structural features from ResNeSt with global semantic priors from a frozen DINOV3 foundation model. A cross-path gating mechanism adaptively regulates semantic injection using local structural cues to preserve boundary fidelity. To further mitigate residual pseudo-label noise, we propose an Uncertainty-Gated Margin (UGM) loss, which dynamically balances margin enforcement and confidence learning based on prediction uncertainty. Extensive experiments on two public histopathological tissue datasets show that C$^2$RM-Seg achieves state-of-the-art performance.

Existing weakly supervised semantic segmentation (WSSS) methods in computational pathology rely on a multi-stage paradigm: class activation map (CAM) generation, offline pseudo-mask refinement, and fully supervised retraining. While established, this decoupled approach presents fundamental limitations. The multi-stage process not only incurs high computational training costs but also suffers from error propagation: local texture biases in shallow CNN layers generate false-positive artifacts that subsequent refinement steps often fail to correct. To address these persistent challenges through a simple yet highly effective approach, we propose the Single-Stage Hierarchical Rectification (SSHR) framework. Rather than passively refining CAMs post-hoc, our method proactively purifies intermediate feature representations during the forward pass. We introduce a Hierarchical Feature Rectification Module (HFRM) that utilizes deep global semantic context to filter out local anomalies in shallow layers. This mechanism generates high-fidelity activation maps directly within a single training loop. Experiments on the LUAD-HistoSeg and BCSS datasets demonstrate that SSHR outperforms state-of-the-art multi-stage methods. Furthermore, SSHR reduces training duration by 2 to 5 times. This efficiency minimizes computational overhead and accelerates clinical translation for large-scale histopathology workflows. The code is available at: https://github.com/trongduc-nguyen/SSHR

Open-vocabulary scene sketch semantic segmentation aims to assign dense semantic labels to sparse line drawings based on flexible category vocabularies specified at inference time, without relying on pixel-level annotations during training. Unlike natural images, sketches lack texture and color cues, making semantic understanding heavily dependent on stroke layout and spatial configuration, a challenge that renders single-layer vision-language features inherently unstable. Our key observation is that attention maps from different Vision Transformer layers encode complementary spatial cues: shallow layers capture global structural layouts, while deeper layers focus on local stroke intersections and object parts. This suggests that cross-layer aggregation provides a more robust structural prior than any individual layer alone. Leveraging this insight, we propose a structure-aware framework built upon \textbf{L}ayer-wise \textbf{A}ccumulated \textbf{S}tructural \textbf{A}ttention (\textbf{LASA}), which aggregates multi-layer attention to guide hierarchical semantic alignment under weak supervision and refine predictions during inference. Experiments on FS-COCO, SFSD, and FrISS show that LASA improves mIoU by $+3.43$, $+8.01$, and $+15.74$ over the prior weakly supervised baselines, demonstrating consistent gains in both segmentation accuracy and spatial coherence. Our source code will be made publicly available.

Weakly Incremental Learning for Semantic Segmentation (WILSS) suffers from the continuous introduction of noisy supervision, which progressively corrupts class-level representations, leading to severe feature drift and semantic corruption, thereby causing newly learned classes to overwrite old ones. To address these issues, we propose a drift-resilient WILSS approach, named SASA, designed to stabilize semantic learning via Semantic Anchors and Spatial Arbitration. Specifically, at the representation level, we introduce semantic anchors of learnable tokens as rigid class-level references to preserve long-term semantic identity. Complementary to this, an elastic residual adaptation facilitates controlled, instance-specific refinement, ensuring a stable yet flexible learning trajectory. At the supervision level, we develop a Spatial Label Arbitration mechanism that performs geometry-aware decisions to directly filter unreliable signals and enforce a strict "one object, one class" constraint. By synergistically stabilizing representations and improving supervision reliability, SASA effectively mitigates feature drift under weak supervision. Extensive experiments on standard benchmarks demonstrate that our approach consistently outperforms existing state-of-the-art methods, particularly in challenging multi-step incremental settings. The code is available at https://github.com/ZhonggaiWang/SASA.

Weakly supervised semantic segmentation (WSSS) trains dense pixel-level segmentation models from partial or coarse annotations such as bounding boxes, scribbles, or image-level tags. While recent work leverages foundation models such as the Segment Anything Model (SAM) to generate pseudo-labels, these approaches typically depend on heuristic prompt choices and offer limited ways to incorporate prior knowledge or heterogeneous labels. We address this gap by taking a neurosymbolic perspective: integrating differentiable fuzzy logic with deep segmentation models. Weak annotations and domain-specific priors are unified as continuous logical constraints that fine-tune SAM under weak supervision. The refined foundation model then produces improved pseudo-labels, from which we train a second-stage prompt-free segmentation model. Experiments on Pascal VOC 2012 and the REFUGE2 optic disc/cup segmentation dataset show that our logic-guided fine-tuning yields higher-quality pseudo-labels, leading to state-of-the-art segmentation accuracy that often exceeds densely supervised baselines.

INTRODUCTION | Fully supervised 3D segmentation of high-resolution ex vivo MRI is limited by the prohibitive cost of volumetric annotation, forcing reliance on sparse 2D slices. Weakly supervised Sparse-to-Dense frameworks bridge this gap, but guidelines remain ambiguous regarding human-centric visual enhancements and transferring optimization strategies across dimensions. We analyze divergent regularization needs for multi-class segmentation of high-resolution ex vivo spinal cord MRI. METHODS | We used 9.4T MRI of multiple sclerosis spinal cords (>104,000 slices) with sparse annotations (428 slices). A 2D Teacher trained on sparse slices generated dense pseudo-labels to train a 3D Student. We systematically evaluated the impact of human-centric preprocessing, spatial augmentation, and soft-label regularization on both architectures. RESULTS | We identified a critical divergence in training dynamics. The 2D Teacher required strong spatial augmentation and soft-labeling to overcome data scarcity, improving White Matter Lesion Dice scores by >11 points. However, propagating these techniques to the 3D Student degraded its performance. Furthermore, human-centric preprocessing (e.g., CLAHE) disrupted global statistical cues, dropping Gray Matter Lesion Dice scores by ~25 points. DISCUSSION | Our study highlights a perception divergence (human-centric contrast enhancement harms machine models) and a regularization conflict across dimensions. 3D architectures trained on dense pseudo-labels exhibit fundamentally different optimization landscapes than 2D counterparts and require distinct, conservative regularization. Code and models: https://github.com/ivadomed/model_seg_sc-gm-lesion_human_ms_exvivo_t2star.

Many image understanding tasks involve identifying what is present and where it appears. However, tasks that address where, such as object discovery, detection, and segmentation, are often considerably more complex than image classification, which primarily focuses on what. One possible reason is that classification-oriented backbones tend to emphasize semantic information about what, while implicitly entangling or suppressing information about where. In this work, we focus on an inductive bias termed what-where separation, which encourages models to represent object appearance and spatial location in a decomposed manner. To incorporate this bias throughout an attentive backbone in the style of Vision Transformer (ViT), we propose the What-Where Transformer (WWT). Our method introduces two key novel designs: (1) it treats tokens as representations of what and attention maps as representations of where, and processes them in concurrent feed-forward modules via a multi-stream, slot-based architecture; (2) it reuses both the final-layer tokens and attention maps for downstream tasks, and directly exposes them to gradients derived from task losses, thereby facilitating more effective and explicit learning of localization. We demonstrate that even under standard single-label classification-based supervision on ImageNet, WWT exhibits emergent multiple object discovery directly from raw attention maps, rather than via additional postprocessing such as token clustering. Furthermore, WWT achieves superior performance compared to ViT-based methods on zero-shot object discovery and weakly supervised semantic segmentation, and it is transferable to various localization setups with minimal modifications. Code will be published after acceptance.

Curating fully annotated datasets for medical image segmentation is labour-intensive and expertise-demanding. To alleviate this problem, prior studies have explored scribble annotations for weakly supervised segmentation. Existing solutions mainly compute losses on annotated areas and generate pseudo labels by propagating annotations to adjacent regions. However, these methods often suffer from inaccurate and unrealistic segmentations due to insufficient supervision and incomplete shape information. In contrast, we first investigate the principle of good scribble annotations, which leads to efficient scribble forms via supervision maximization and randomness simulation. We further introduce regularization terms to encode the spatial relationship and the shape constraints, where the EM algorithm is utilized to estimate the mixture ratios of label classes. These ratios are critical in identifying the unlabeled pixels for each class and correcting erroneous predictions, thus the accurate estimation lays the foundation for the incorporation of spatial prior. Finally, we integrate the efficient scribble supervision with the prior into a framework, referred to as ZScribbleSeg, and apply it to multiple scenarios. Leveraging only scribble annotations, ZScribbleSeg achieves competitive performance on six segmentation tasks including ACDC, MSCMRseg, BTCV, MyoPS, Decathlon-BrainTumor and Decathlon-Prostate. Our code will be released via https://github.com/DLwbm123/ZScribbleSeg.

Weakly Supervised Semantic Segmentation (WSSS) with image-level labels typically leverages Class Activation Maps (CAMs) to achieve pixel-level predictions. Recently, Contrastive Language-Image Pre-training (CLIP) has been introduced to generate CAMs in WSSS. However, previous WSSS methods solely adopt CLIP's vision-language paired property for dense localization, neglecting its inherently limited dense knowledge across both visual and text modalities, which renders CAM generation suboptimal. In this work, we propose DiCLIP, a novel WSSS framework that leverages the generative diffusion model to enhance CLIP's dense knowledge across two modalities. Specifically, Visual Correlation Enhancement (VCE) and Text Semantic Augmentation (TSA) modules are proposed for dense prediction enhancement. To improve the spatial awareness of visual features, our VCE module utilizes diffusion's reliable spatial consistency to mitigate the over-smoothing issue in CLIP's attention. It designs the Attention Clustering Refinement (ACR) module to reliably extract diverse correlation maps from the diffusion model. The correlation maps act as a diversity bias for CLIP's self-attention, recursively pushing its visual features towards a more discriminative dense distribution. To augment the semantics of text embeddings, our TSA module argues that a single text modality is insufficient to encompass the variability of visual categories. Thus, we leverage diffusion's generative power to maintain a dynamic key-value cache model, shifting CAM generation from a patch-text matching mechanism to a novel visual knowledge retrieval paradigm. With these enhancements, DiCLIP not only outperforms state-of-the-art methods on PASCAL VOC and MS COCO but also significantly reduces training costs. Code is publicly available at https://github.com/zwyang6/DiCLIP.

In pathology, the spatial distribution and proportions of tissue types are key indicators of disease progression, and are more readily available than fine-grained annotations. However, these assessments are rarely mapped to pixel-wise segmentation. The task is fundamentally underdetermined, as many spatially distinct segmentations can satisfy the same global proportions in the absence of pixel-wise constraints. To address this, we introduce Variational Segmentation from Label Proportions (VSLP), a two-stage framework that infers dense segmentations from global label proportions, without any pixel-level annotations. This framework first leverages a pre-trained transformer model with test-time augmentation to produce a pixel-wise confidence estimate. In the second stage, these estimates are fused by solving a variational optimization problem that incorporates a Wasserstein data fidelity term alongside a learned regularizer. Unlike end-to-end networks, our variational method can visualize the fidelity-regularization energy, resulting in more interpretable segmentation. We validate our approach on two public datasets, achieving superior performance over existing weakly supervised and unsupervised methods. For one of these datasets, proportions have been estimated by an experienced pathologist to provide a realistic benchmark to the community. Furthermore, the method scales to an in-house dataset with noisy pathologist labels, severely outperforming state-of-the-art methods, thereby demonstrating practical applicability. The code and data will be made publicly available upon acceptance at https://github.com/xiaoliangpi/VSLP.

Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data requires significant workload demands from experienced pathologists, limiting the application of deep learning. To overcome this challenge, relaxing the label conditions to image-level classification labels allows for more data to be used and more scenarios to be enabled. One approach is to leverage Class Activation Map (CAM) to generate pseudo pixel-level annotations for semantic segmentation with only image-level labels. However, this method fails to thoroughly explore the essential characteristics of pathology images, thus identifying only small areas that are insufficient for pseudo masking. In this paper, we propose a novel shuffle-based feedback learning method inspired by curriculum learning to generate higher-quality pseudo-semantic segmentation masks. Specifically, we perform patch level shuffle of pathology images, with the model adaptively adjusting the shuffle strategy based on feedback from previous learning. Experimental results demonstrate that our proposed approach outperforms state-of-the-arts on three different datasets.

Weakly supervised semantic segmentation aims to achieve pixel-level predictions using image-level labels. Existing methods typically entangle semantic recognition and object localization, which often leads models to focus exclusively on sparse discriminative regions. Although foundation models show immense potential, many approaches still follow the tightly coupled optimization paradigm, struggling to effectively alleviate pseudo-label noise and often relying on time-consuming multi-stage retraining or unstable end-to-end joint optimization. To address the above challenges, we present ModuSeg, a training-free weakly supervised semantic segmentation framework centered on explicitly decoupling object discovery and semantic assignment. Specifically, we integrate a general mask proposer to extract geometric proposals with reliable boundaries, while leveraging semantic foundation models to construct an offline feature bank, transforming segmentation into a non-parametric feature retrieval process. Furthermore, we propose semantic boundary purification and soft-masked feature aggregation strategies to effectively mitigate boundary ambiguity and quantization errors, thereby extracting high-quality category prototypes. Extensive experiments demonstrate that the proposed decoupled architecture better preserves fine boundaries without parameter fine-tuning and achieves highly competitive performance on standard benchmark datasets. Code is available at https://github.com/Autumnair007/ModuSeg.

Meta-learning aims to uniformly sample homogeneous support-query pairs, characterized by the same categories and similar attributes, and extract useful inductive biases through identical network architectures. However, this identical network design results in over-semantic homogenization. To address this, we propose a novel homologous but heterogeneous network. By treating support-query pairs as dual perspectives, we introduce heterogeneous visual aggregation (HA) modules to enhance complementarity while preserving semantic commonality. To further reduce semantic noise and amplify the uniqueness of heterogeneous semantics, we design a heterogeneous transfer (HT) module. Finally, we propose heterogeneous CLIP (HC) textual information to enhance the generalization capability of multimodal models. In the weakly-supervised few-shot semantic segmentation (WFSS) task, with only 1/24 of the parameters of existing state-of-the-art models, TLG achieves a 13.2% improvement on Pascal-5\textsuperscript{i} and a 9.7% improvement on COCO-20\textsuperscript{i}. To the best of our knowledge, TLG is also the first weakly supervised (image-level) model that outperforms fully supervised (pixel-level) models under the same backbone architectures. The code is available at https://github.com/jarch-ma/TLG.

Semantic segmentation in open-vocabulary scenarios presents significant challenges due to the wide range and granularity of semantic categories. Existing weakly-supervised methods often rely on category-specific supervision and ill-suited feature construction methods for contrastive learning, leading to semantic misalignment and poor performance. In this work, we introduce a novel weakly-supervised approach, SynSeg, to address the challenges. SynSeg performs Multi-Category Contrastive Learning (MCCL) as a stronger training signal which robustly injecting intra- and inter-category knowledge during training. We also propose a new feature reconstruction framework named Feature Synergy Structure (FSS). FSS reconstructs discriminative features for contrastive learning through prior fusion and semantic-activation-map enhancement, effectively avoiding the foreground bias introduced by the visual encoder. Furthermore, SynSeg is a lightweight end-to-end solution capable for real-time inference. In general, SynSeg effectively improves the abilities in semantic localization and discrimination under weak supervision in an efficient manner. Extensive experiments on benchmarks demonstrate that our method outperforms state-of-the-art (SOTA) performance, with mIoU score gains ranging from 0.6% up to 8.9% across all reported benchmarks.