cs.HCApr 11, 2026

Empathic and agentic artificial intelligence in nursing: perspectives on a human-centered framework for cancer care navigation in the United States

Authors: Tyra Girdwood, Saba Kheirinejad, Parnian Kheirkhah Rahimabad, Brianna M. White, Robert L Davis, David L Schwartz, Arash Shaban-Nejad

Organizations: University of Tennessee Health Science Center, College of Nursing, Memphis · University of Tennessee Health Science Center, Center for Biomedical Informatics, Department of Pediatrics, Memphis · University of Tennessee Health Science Center, Department of Radiation Oncology, Memphis, USA

Abstract

For patients experiencing cancer, nurse navigation can ease the burden of complex care by enhancing coordination of health services and patient outcomes. However, in under-resourced areas, trained nurse navigators may be limited or non-existent. In the United States, artificial intelligence (AI)-enabled digital health tools are increasingly available and may help address gaps in care coordination; however, most are not designed to specifically support nursing. This perspective piece discusses a human-centered AI framework that integrates empathic and agentic approaches grounded in the American Nurses Association's code of ethics to support nurses in the United States in cancer care navigation. The framework could augment, not replace, human empathy and agency while improving nurse workflow, patient-clinician relationships, and care coordination services in under-resourced areas.

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