Brainagent

Momentum

1 paper in the last four weeks, down 67% on the four weeks before. 0.0% of all new papers.

Jul 6Week of Sep 21

Latest papers 18

Sep 8, 2026cs.MA

MorphoOrgaAgent: A Foundation-Model-Based Multi-Agent System for Autonomous Organoid Analysis

Organoids are three-dimensional tissue models whose morphology provides important insights into tumor development, disease progression, and drug testing. Extracting these morphological features relies heavily on manual segmentation, which is time-consuming and labor-intensive. Furthermore, performing quantitative statistical analysis typically requires custom coding skills and a mathematical background, presenting a major barrier for experimental biologists. To address these challenges, we introduce MorphoOrgaAgent, a multi-agent framework that achieves zero-shot organoid segmentation, automated data analysis, and report generation based on natural language input. The framework consists mainly of three core components: a TaskUnderstandingAgent that identifies requested measurements and visualization types; a hybrid segmentation module that combines Cellpose-derived geometric prompts with text prompts to guide SAM3 for zero-shot organoid instance segmentation; and a ReportAgent that computes quantitative metrics and compiles them alongside generated visualizations into a structured report. We further introduce MorphoOrgaVQA, a benchmark designed for quantitative evaluation of agent systems in organoid morphology analysis. Experimental results demonstrate that MorphoOrgaAgent handles both explicit and descriptive user requests, produces measurements closely matching ground truth, and generates complete analysis reports without requiring manual programming. The complete source code and MorphoOrgaVQA benchmark are publicly available at https://github.com/peng-lab/MorphoOrgaAgent.
Aug 7, 2026cs.AI

Agent-MD: Selective LLM Intervention with Event-Driven Escalation for Stateful GCMC--MD Campaigns

Long-running molecular simulation campaigns require repeated continuation from saved states, provenance-aware progression, adaptive assessment, and occasional interpretation of workflow conditions that cannot be resolved safely by fixed rules. Here, we present Agent-MD, a framework that places large language model (LLM) reasoning selectively at campaign construction and event-triggered review, while routine simulation, analysis, continuation, archiving, and state progression are handled by a persistent rule-based campaign agent using approved policies and explicit state records. Agent-MD was demonstrated in a grand canonical Monte Carlo-molecular dynamics (GCMC-MD) water-vapor desorption campaign comprising five montmorillonite systems and three sequential relative-humidity states (RH = 0.9-0.3-0.1). Across 15 system-RH states, the workflow completed 120 segmented simulation cycles with state-specific sampling lengths and provenance-aware restart inheritance. Routine production required no live reasoning-agent invocation, while one state reached a review boundary; two preserved incidents were subsequently evaluated through blinded reasoning-agent replay, which identified the underlying workflow problems and recommended appropriate follow-up actions. The simulations also revealed distinct composition-dependent low-RH responses, with Ca-bearing montmorillonite retaining more interlayer water and maintaining a larger basal spacing than the Na- and K-bearing systems, while the highest-charge Na system retained more residual water under dry conditions. These results demonstrate that long-running scientific workflows need not place every operation inside an LLM reasoning loop: selective reasoning can instead be combined with deterministic execution, structured evidence, and validated control handoffs to provide reproducible and auditable agent-assisted molecular simulation.
Aug 4, 2026cs.CL

OneDayAgent: Towards a Long-Horizon Harness for Autonomous Agents

LLM agents are increasingly applied to open-ended everyday requests that span work, study, and life. These tasks are long-horizon, cross-environment, and multimodal, forcing the agent to preserve goals and constraints across many steps while navigating heterogeneous tools and attachments. While prior work has addressed individual failure modes such as goals drift, states loss, and context overflow, whether a single harness can manage them jointly and remain effective across backends has received less study. We present OneDayAgent, a long-horizon harness for autonomous agents. OneDayAgent turns an open-ended request into a managed execution process that decomposes tasks into bounded subtasks, maintains execution memory under context pressure, and verifies and repairs the final deliverable. We evaluate OneDayAgent on AgentIF-OneDay across 104 tasks. With the GLM-5.2 backend, OneDayAgent sets a new state of the art with an overall score of 0.821. The same harness runs across five backend LLMs from three model families, indicating the harness generalizes across backends without tuning, even as different models induce distinct execution styles under the same workflow.
Aug 4, 2026cs.AI

UrbanAgent: A Tool-Augmented Agent for Cross-System Urban Tasks

Modern cities rely on an increasing number of digital services to operate, but residents' daily needs are still difficult to meet. Services are fragmented and have little interoperability, placing a heavy operational burden on users. Existing digital platforms, urban foundation models, and intelligent assistants each address only isolated aspects of an urban task. But they struggle to reliably convert complex natural-language requests into executable cross-system workflows. We propose Urban-Agent, a tool-augmented agent framework for cross-system urban tasks. It couples the cognitive and reasoning capabilities of a large language model with a tool-set supporting code execution, API calls, and Model Context Protocol. Through one adaptive closed loop, it clarifies missing information before acting, grounds tool use in live observations, and aligns the final response with observed evidence and task constraints. To address the evaluation gap, we introduce Urban-Eval, a benchmark specifically designed for cross-system urban request. Unlike prior benchmarks that assess either general tool use or urban knowledge and reasoning, Urban-Eval evaluates both task results and execution quality, including required tool coverage, dependency validity, and evidence traceability. Experimental results indicate that Urban-Agent reaches a 71% task success rate, 10 points above the strongest baseline. This lead holds across GPT-5-mini, Gemini-2.5-flash, DeepSeek-V4-flash, and Qwen3-235B-A22B.
Jul 24, 2026cs.MA

When Language Models Meet NeuroGraphs: Exploring Enhanced Agentic LLM Framework Towards Brain Network Analysis

Brain network analysis is crucial for understanding cognition and neurological disorders, yet existing deep learning methods mainly treat connectome analysis as a graph-to-logit classification problem, offering limited explanatory reasoning. Large language models (LLMs) provide a promising interface for knowledge-intensive scientific analysis, but directly applying general-purpose LLMs to brain networks remains challenging due to the structure-language gap, limited neuroscience grounding, and overconfident positive predictions. In this paper, we propose \textbf{BrainAgent}, an agentic LLM framework for knowledge-enhanced brain network analysis. BrainAgent reformulates connectome classification as an iterative process of topology-aware understanding, external retrieval, reasoning, and reflection. Specifically, it first converts raw brain networks into compact multi-level structural descriptions through brain-specific analysis tools, then retrieves relevant neuroscience knowledge and task-specific cases to ground the reasoning process, and finally generates structured predictions with reflective verification. Experiments on four public rs-fMRI datasets show that BrainAgent consistently improves different closed-source and open-source LLM backbones over direct prompting and standard reasoning baselines. Further ablation and interpretability analyses demonstrate the effectiveness of each component and show that BrainAgent produces more comprehensive, multi-level, and verifiable explanations.These results indicate that agentic LLMs provide a practical route toward interpretable and knowledge-grounded brain network analysis.
Jul 6, 2026cs.AI

OptiAgent: End-to-End Optimization Modeling via Multi-Agent Iterative Refinement

We propose OptiAgent, a multi-agent framework that, given a natural language description of an Operations Research problem, is able to output a solver-ready mathematical formulation as well as executable code. Our architecture prioritizes the mathematical modeling step, where dedicated agents extract structures, such as decision variables and constraints, enabling iterative self-correction. We introduce a novel multi-loop validation architecture with four specialized feedback mechanisms, each targeting a distinct failure mode such as misinterpretation, structural defects, mathematical inconsistencies, validation failures, and code errors. Alongside accuracy, our modular design improves the process of solving optimization problems by improving transparency, as each agent exposes its reasoning and feedback, making the full modeling process auditable. Our framework achieves state-of-the-art performance on 3 out of 4 benchmarks across LP, MILP, and Nonlinear Programming tasks, while remaining highly competitive on the remaining dataset.
Jun 30, 2026cs.AI

TreeAgent: A Generalizable Multi-Agent Framework for Automated Bias Labeling in Forestry via Compiled Expert Rules and Vision-Language Models

Human-labeled data are widely used as reference annotations in ML, despite known variability across annotators in many expert-driven domains. In addition, expert annotation is slow, inconsistent, and remains a major bottleneck for scaling tasks like tree height bias classification in forestry remote sensing. We propose a multi-agent system (MAS) that orchestrates expert decision trees with Vision-Language Models (VLMs), treating the decision tree as a structural prior while VLMs perform localized semantic perception at individual nodes, with multi-agent voting to mitigate VLM stochasticity. We formalize a Decoupled Declarative Decision (D3) Framework that enables zero-modification generalization across diverse expert-defined decision structures. On a tree bias classification testbed, our framework outperforms supervised ML baselines and reduces the amount of expert labeling effort required. These results suggest that agentic orchestration of VLMs with expert priors can reproduce expert-defined labeling procedures at substantially lower annotation cost while maintaining interpretability.
Jun 30, 2026cs.CV

AeroVerse-SatAgent: UAV-Satellite Collaborative Spatial Reasoning Inspired by the Dual Visual Pathway Theory of Cognitive Neuroscience

With the rapid advancement of aerospace embodied intelligence, enabling Unmanned Aerial Vehicles (UAVs) to autonomously understand and reason about complex environments has become increasingly important. However, existing UAV-based spatial reasoning approaches face critical limitations: single-view perception renders them vulnerable to occlusions and perspective distortions, while most VLMs lack explicit geometric modeling, relying on semantic cues and yielding inconsistent reasoning under viewpoint and scale variations. To address these challenges, we propose SatAgent, a UAV-Satellite collaborative spatial reasoning model inspired by the dual-pathway mechanism of the human visual system. By jointly leveraging satellite and UAV perspectives, SatAgent enables robust, accurate reasoning in complex urban environments. We first introduce a Geometric-Aware 3D Reconstruction Encoder that elevates 2D UAV features into explicit 3D spatial representations. Next, we design a multi-view topology-semantic alignment module integrating cross-view features within a unified BEV coordinate system. We further introduce a multi-view consistency loss encouraging viewpoint-invariant representations. Finally, we construct SatAgent-SR130K, the first large-scale UAV-Satellite collaborative multi-view spatial reasoning dataset. Experiments show SatAgent outperforms state-of-the-art general-purpose foundation models and specialized spatial reasoning models by 25.91% and 11.69%, respectively, across diverse tasks, achieving particularly high accuracy in complex geometric relationship reasoning.
Jun 24, 2026cs.AI

BrainAgent: A Large Language Model-Driven Multi-Agent Framework for Autonomous Brain Signal Understanding

Brain-Computer Interfaces (BCIs) and brain signal understanding are pivotal for clinical health and next-generation interactions. Despite this significance, its widespread adoption in real-world scenarios remains restricted, primarily because current analytical paradigms lack sufficient agentic intelligence. First, existing methodologies impose prohibitive technical barriers, requiring extensive specialized expertise. Second, they remain inherently static and task-specific, failing to execute the complex, long-horizon workflows essential for real-world deployment. To accelerate the democratization of brain signal understanding, we draw inspiration from Large Language Models (LLMs) to introduce BrainAgent, an LLM-driven multi-agent framework designed to ground abstract natural language intent into rigorous, executable, and end-to-end processing pipelines. BrainAgent employs a hierarchical architecture where a central supervisor orchestrates specialized sub-agents for adaptive task decomposition and execution. Furthermore, we establish a comprehensive, systematic benchmark for evaluating agentic systems in brain signal analysis. Empirical results demonstrate that BrainAgent effectively automates complex workflows with superior reliability, marking a paradigm shift toward democratized brain signal understanding.
Jun 16, 2026cs.RO

Agent Utilities over Generalized Voronoi Regions and their Gradients

In this paper, we generalize the concept of Voronoi regions, define agent utility as the integral of a utility density over the corresponding Voronoi region, derive gradients of the utility, and illustrate the approach in a two-team example from soccer. The generalization of Voronoi regions is in the form of so-called Cost-Induced Voronoi (CIV) regions, where the agent state space may differ from the space being partitioned. One example of such regions is when the cost is given by the optimal solution of an LQR control problem. Then the agent states include position as well as velocity, while the partitioned space only includes positions. The agent utility is defined by integrating some utility density over the CIV region of the agent. This utility density might be the probability density of some beneficial event, such as receiving a pass in soccer. The utility is then the overall probability of receiving a pass and the gradient represents a way to improve that probability. We show how this utility gradient can be computed using the Reynolds Transport Theorem from fluid mechanics, and that this approach achieves similar accuracy while reducing computation time by about an order of magnitude compared to a baseline finite-difference approximation.
May 22, 2026cs.MA

Self-Refining Topology Optimization via an LLM-Based Multi-Agent Framework

Topology optimization is a widely used design method that produces optimized material distributions for prescribed objectives and constraints through well-established numerical algorithms. Throughout the workflow, engineers make a series of decisions ranging from setting and adjusting numerical parameters to assessing whether the converged design meets considerations beyond those explicitly included in the optimization problem, such as physical feasibility. These decisions, which draw on domain expertise, interfere with the autonomous design process. To address this difficulty, this study presents TopOptAgents, a multi-agent system for automating not only the design process but also decision-making during the key stages of the topology optimization process. TopOptAgents consists of six LLM-based agents collaborating through iterative self-refinement cycles spanning problem formulation, validation, code generation and execution, and quality assessment of the optimized structure. This process enables error correction and progressive improvement of both the optimization setup and resulting design. The framework is demonstrated on optimization problems selected to cover a range of settings that differ in their literature coverage and numerical characteristics The benefits of iterative self-refinement are found to be particularly pronounced for problem classes where the pretrained language model has limited prior exposure, such as formulations whose literature and open-source implementations are comparatively sparse. In such cases, the proposed framework reliably produces converged designs where a single state-of-the-art LLM struggles, suggesting that self-refinement broadens the range of topology optimization problems that LLM-based automation can reliably address.
May 21, 2026cs.CV

EvoIR-Agent: Self-Evolving Image Restoration Agentic System via Experience-Driven Learning

Multimodal Large Language Model (MLLM)-driven image restoration agent demonstrates effectiveness in degradation coupling scenarios by flexibly selecting tools and determining removal orders. However, its zero-shot planning often fails without experience, necessitating severe trial-and-error overhead to achieve satisfactory outcomes. Currently, two paradigms are employed to address this issue, yet a dilemma persists: Training-based methods embed intrinsic experience into parameters, achieving high inference efficiency but lacking compatibility with new tools or degradations. In contrast, training-free methods utilize explicit experience storage for compatibility but still incur trial-and-error overhead due to naive experience. To resolve the dilemma, we propose EvoIR-Agent, which first systematically formulates the experience components of a training-free image restoration agent. Subsequently, a hierarchical experience pool is constructed, which enables coarse-to-fine guidance for diverse tools and removal orders. Furthermore, a self-evolving mechanism is introduced to update the pool from scratch using accumulated records, thereby greatly improving performance and efficiency. Extensive experiments reveal that EvoIR-Agent achieves a significant lead in the full reference metrics and yields a Pareto-optimal balance, which outperforms state-of-the-art methods in performance and is 61% more efficient.
May 20, 2026cs.AI

TO-Agents: A Multi-Agent AI Pipeline for Preference-Guided Topology Optimization

Topology optimization can generate efficient structures, but designers often must manually translate qualitative intent, such as desired visual style, product experience, or manufacturability into solver settings that are not directly tied to those preferences. We present TO-Agents, a multi-agent AI framework that connects natural-language design intent with iterative topology optimization. The framework converts a human-provided problem description into validated solver inputs, runs a topology optimization solver, renders the resulting 3D topology, and uses multi-view vision-language reasoning with an independent judge agent to critique each result and revise solver parameters. We evaluate the framework on two long-horizon design tasks: a cantilever beam benchmark and a phone-stand product design. In both tasks, the designer specifies an aesthetic preference for hierarchically branched structures inspired by natural tree morphologies, and the system performs four revision cycles across ten independent replicates. TO-Agents produces at least one preference-aligned design in 60% of trials for each case study, corresponding to up to 6x more successful trials than an ablated pipeline without visual or historical feedback. Judge scores and human evaluations show that the pipeline can identify effective parameter levers, recover from poor revisions, and expand design exploration. A manufacturing agent further post-processes top-ranked designs for additive manufacturing, enabling end-to-end intent-to-prototype design. We also identify failure modes, including overshooting, selective memory, misplaced tools, and incorrect parameter reasoning. These results suggest that agentic topology optimization can shift designers from low-level parameter tuning toward higher-level specification of form and function, while highlighting safeguards needed for reliable autonomous engineering design.
May 11, 2026cs.AI

The Agent Use of Agent Beings: Agent Cybernetics Is the Missing Science of Foundation Agents

LLM-based foundation agents that perceive, reason, and act across thousands of reasoning steps are rapidly becoming the dominant paradigm for deploying artificial intelligence in open-ended, long-horizon complex tasks. Despite this significance, the field remains overwhelmingly engineering-driven. Engineering practice has converged on useful primitives (tool loops, memory banks, harnesses, reflection steps), yet these are assembled by empirical trial and error rather than from first principles. Fundamental questions remain open: under what conditions does a long-running agent remain on-task? How should an agent respond when its environment exceeds its representational capacity? What architectural properties are necessary for safe self-improvement? We argue that cybernetics, the mid-twentieth-century science of control and communication in complex systems, provides the missing theoretical scaffold for foundation agents. By mapping six canonical laws of classical cybernetics onto six agent design principles, and synthesizing those principles into three engineering desiderata (reliability, lifelong running, and self-Improvement), we arrive at a framework termed Agent Cybernetics. Three application domains, code generation, computer use and automated research, exemplify the analytical framework of agent cybernetics by identifying failure modes and concrete engineering recommendations. We hope that agent cybernetics opens a new research venue and establishes the scientific foundation that foundation agents need for principled, reliable real-world deployment.
Apr 29, 2026cs.CR

Agent Name Service (ANS): A Proof-of-Concept Trust Layer for Secure AI Agent Discovery, Identity, and Governance in Kubernetes

Autonomous AI agent ecosystems require stronger mechanisms for secure discovery, identity verification, capability attestation, and policy governance. Current deployments frequently lack (1) uniform agent discovery, (2) cryptographic agent authentication, (3) capability proofs that protect secrets, and (4) enforceable policy controls. This paper presents an implementation-oriented proof of concept for the Agent Name Service (ANS), a DNS-inspired trust layer for AI agent discovery and interoperability in Kubernetes, grounded in the ANS protocol specification~\cite{huang2025ans}. The implementation uses Decentralized Identifiers (DIDs), Verifiable Credentials (VCs), policy-as-code enforcement with Open Policy Agent (OPA), and Kubernetes-native integration patterns (CRDs, admission controls, service mesh integration). In a demo research environment (3-node cluster, 50-agent workflow simulation), we observe sub-10ms response in demonstrated service paths and full success for scripted demo deployment scenarios. We explicitly scope these findings as proof-of-concept evidence rather than production certification. We further provide a threat model, assumptions, and limitations to separate implemented evidence from protocol-defined and roadmap capabilities. The result is an evidence-grounded pathway from ANS protocol concepts to reproducible engineering practice for secure multi-agent systems.
Apr 28, 2026cs.SE

SAFEdit: Does Multi-Agent Decomposition Resolve the Reliability Challenges of Instructed Code Editing?

Instructed code editing is a significant challenge for large language models (LLMs). On the EditBench benchmark, 39 of 40 evaluated models obtain a task success rate (TSR) below 60 percent, highlighting a gap between general code generation and the ability to perform instruction-driven editing under executable test constraints. To address this, we propose SAFEdit, a multi-agent framework for instructed code editing that decomposes the editing process into specialized roles to improve reliability and reduce unintended code changes. A Planner Agent produces an explicit, visibility-aware edit plan, an Editor Agent applies minimal, literal code modifications, and a Verifier Agent executes real test runs. When tests fail, SAFEdit uses a Failure Abstraction Layer (FAL) to transform raw test logs into structured diagnostic feedback, which is fed back to the Editor to support iterative refinement. We compare SAFEdit against both prior single-model results reported for EditBench and an implemented ReAct single-agent baseline under the same evaluation conditions. We used EditBench to evaluate SAFEdit on 445 code editing instances in five languages (English, Polish, Spanish, Chinese, and Russian) under varying spatial context variants. SAFEdit achieved 68.6 percent TSR, outperforming the single-model baseline by 3.8 percentage points and the ReAct single-agent baseline by 8.6 percentage points. The iterative refinement loop was found to contribute 17.4 percentage points to SAFEdit's overall success rate. SAFEdit's automated error analysis further indicates a reduction in instruction-level hallucinations compared to single-agent approaches, providing an additional framework component for interpreting failures beyond pass or fail outcomes.
Apr 18, 2026cs.CL

GenericAgent: A Token-Efficient Self-Evolving LLM Agent via Contextual Information Density Maximization (V1.0)

Long-horizon large language model (LLM) agents are fundamentally limited by context. As interactions become longer, tool descriptions, retrieved memories, and raw environmental feedback accumulate and push out the information needed for decision-making. At the same time, useful experience gained from tasks is often lost across episodes. We argue that long-horizon performance is determined not by context length, but by how much decision-relevant information is maintained within a finite context budget. We present GenericAgent (GA), a general-purpose, self-evolving LLM agent system built around a single principle: context information density maximization. GA implements this through four closely connected components: a minimal atomic tool set that keeps the interface simple, a hierarchical on-demand memory that only shows a small high-level view by default, a self-evolution mechanism that turns verified past trajectories into reusable SOPs and executable code, and a context truncation and compression layer that maintains information density during long executions. Across task completion, tool use efficiency, memory effectiveness, self-evolution, and web browsing, GA consistently outperforms leading agent systems while using significantly fewer tokens and interactions, and it continues to evolve over time. Project: https://github.com/lsdefine/GenericAgent
Dec 12, 2025cs.AI

AGAPI-Agents: An Open-Access Agentic AI Platform for Accelerated Materials Design on AtomGPT.org

Agentic AI systems increasingly connect large language models (LLMs) to external scientific tools, yet whether and when tool access improves prediction accuracy remains uncharacterized. We present AGAPI (AtomGPT.org API), an open access platform integrating eight open-source LLMs with 18 REST endpoints (28 agent tools, 50 web apps) spanning materials databases, force fields, tight-binding band structures, X-ray diffraction, and protein structure. A three-evaluation residual decomposition on JARVIS-Leaderboard electronic-structure test sets separates agent pipeline fidelity from inherited density functional theory (DFT) functional bias. For bulk modulus and bandgap the agent reproduces JARVIS-DFT entries to numerical precision, so the experimental-reference degradation is functional bias, not agentic malfunction. On memorization-resistant test sets (57 defective supercells, 60 hypothetical compositions), tool-augmented mean absolute error (MAE) is below 0.005 eV versus 1.25 to 1.86 eV tool-free, confirming tools are indispensable where parametric knowledge is unavailable. We further demonstrate autonomous multi-step workflows including 10-operation defect-engineering pipelines. AGAPI is available at https://github.com/atomgptlab/agapi.