Latent Diffusion Model

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Period ending 2026-09-21

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A weekly snapshot of new work published in Latent Diffusion Model.

Period ending 2026-09-07

1 new paper

A weekly snapshot of new work published in Latent Diffusion Model.

92 papers

Latest in Latent Diffusion Model

May 16, 2026cs.SD

Taming Audio VAEs via Target-KL Regularization

Latent diffusion models have emerged as the dominant paradigm for many generation tasks including audio generation such as text-to-audio, text-to-music and text-to-speech. A key component of latent diffusion is an autoencoder (VAE) that compresses high-dimensional signals into a low frame rate continuous representation that is conducive for downstream prediction. Regularizing these VAEs is challenging, as there is a trade-off between over-regularized (poor output quality) and under-regularized (difficult to predict) latent representations. We propose a framework for studying this trade-off through compression and train Audio VAEs at specific bitrates via target-KL regularization. This allows direct comparison to well-studied discrete neural audio codec models, and the construction of rate-distortion curves for audio VAEs. We evaluate the impact of target-KL regularization on text-to-sound generation and find that sweeping compression rates is helpful in identifying the optimal generation setting.
Prem Seetharaman, Rithesh Kumar
May 16, 2026cs.CV

HighSync: High-Quality Lip Synchronization via Latent Diffusion Models

We present HighSync, an end-to-end diffusion-based framework for high-fidelity lip synchronization that generates photorealistic talking-face videos aligned with arbitrary input audio. Existing approaches consistently struggle to reconcile image quality with synchronization accuracy, producing either visually degraded outputs or temporally inconsistent lip movements. HighSync addresses both challenges simultaneously and, to our knowledge, is the first lip sync model to operate natively at 512*512 resolution, positioning it as a viable solution for professional production environments such as the film and broadcast industries. Central to our approach is the identification and systematic elimination of a data leakage phenomenon that has silently undermined temporal modeling in prior work, preventing models from developing a genuine dependence on the audio signal. Comprehensive evaluations across both perceptual quality and synchronization accuracy metrics confirm that HighSync achieves state-of-the-art performance on both fronts. Source code, pre-trained models, and supplementary video results are publicly available at: https://github.com/saeed5959/high_sync
Saeed Firouzi Daghigh, Majid Iranpour Mobarekeh, Mostafa Alavi +1
May 15, 2026cs.CV

Face inpainting with Identity Preserving Latent Diffusion Models

Face inpainting techniques recover missing or occluded facial regions in a visually realistic manner, but preserving the identity in the final output remains a fundamental challenge. Identity consistency is crucial for downstream applications such as face recognition, digital forensics, and human-computer interaction, where even subtle identity distortions can significantly degrade performance or trust. Although diffusion-based generative models have recently achieved remarkable progress in image inpainting, they often struggle to faithfully retain individual-specific facial characteristics. On the other hand, existing identity-aware methods typically rely on costly fine-tuning, auxiliary supervision, or exhibit limited robustness to diverse occlusions, poses, and facial variations. To address these limitations, we propose ID-ControlNet, an identity-preserving face inpainting framework built upon latent diffusion models. Based on ControlNet architecture, our approach conditions the diffusion process on facial identity embeddings extracted from a pretrained face recognition network. This design enables reconstruction of occluded facial regions while maintaining global facial coherence and identity fidelity. Furthermore, we introduce an identity consistency and triplet loss training strategy that explicitly enforces alignment between the generated face and the target identity representation. Extensive experiments on CelebA-HQ, FFHQ, and on a new E-Mask dataset demonstrate that ID-ControlNet significantly improves identity preservation over standard diffusion-based inpainting methods, achieving performance comparable to SOTA identity-aware approaches.
João Santos, Carlos Santiago, Manuel Marques
May 15, 2026cs.CV

Efficient Image Synthesis with Sphere Latent Encoder

Few-step image generation has seen rapid progress, with consistency and meanflow-based methods significantly reducing the number of sampling steps. Despite their low inference cost, these approaches often suffer from training instability and limited scalability. Sphere Encoder is a recent alternative that produces high-quality images in only a few steps; however, it requires repeated transitions between the pixel space and latent space during inference while jointly optimizing reconstruction and generation within a single architecture. This design leads to computational inefficiency and objective conflict between reconstruction and generation. To address these limitations, we decouple the framework into a fixed pretrained image encoder and a separate latent denoising model trained entirely in a spherical latent space. Our approach eliminates repeated pixel-space operations during training and inference, improving efficiency and allowing reconstruction and generation to specialize independently. On Animal-Faces, Oxford-Flowers and ImageNet-1K datasets, our method significantly outperforms Sphere Encoder in both generation quality and inference speed, while achieving competitive results against strong few-step and multi-step baselines.
Tung Do, Thuan Hoang Nguyen, Hao Li
May 14, 2026cs.CV

RefDecoder: Enhancing Visual Generation with Conditional Video Decoding

Video generation powers a vast array of downstream applications. However, while the de facto standard, i.e., latent diffusion models, typically employ heavily conditioned denoising networks, their decoders often remain unconditional. We observe that this architectural asymmetry leads to significant loss of detail and inconsistency relative to the input image. To address this, we argue that the decoder requires equal conditioning to preserve structural integrity. We introduce RefDecoder, a reference-conditioned video VAE decoder by injecting high-fidelity reference image signal directly into the decoding process via reference attention. Specifically, a lightweight image encoder maps the reference frame into the detail-rich high-dimensional tokens, which are co-processed with the denoised video latent tokens at each decoder up-sampling stage. We demonstrate consistent improvements across several distinct decoder backbones (e.g., Wan 2.1 and VideoVAE+), achieving up to +2.1dB PSNR over the unconditional baselines on the Inter4K, WebVid, and Large Motion reconstruction benchmarks. Notably, RefDecoder can be directly swapped into existing video generation systems without additional fine-tuning, and we report across-the-board improvements in subject consistency, background consistency, and overall quality scores on the VBench I2V benchmark. Beyond I2V, RefDecoder generalizes well to a wide range of visual generation tasks such as style transfer and video editing refinement.
Xiang Fan, Yuheng Wang, Bohan Fang +2
May 13, 2026cs.LG

Di-BiLPS: Denoising induced Bidirectional Latent-PDE-Solver under Sparse Observations

Partial differential equations (PDEs) are fundamental for modeling complex natural and physical phenomena. In many real-world applications, however, observational data are extremely sparse, which severely limits the applicability of both classical numerical solvers and existing neural approaches. While neural methods have shown promising results under moderately sparse observations, their inference efficiency at high resolutions is limited, and their accuracy degrades substantially in the extremely sparse regime. In this work, we propose the Di-BiLPS, a unified neural framework that effectively handle both forward and inverse PDE problems under extremely sparse observations. Di-BiLPS combines a variational autoencoder to compress high-dimensional inputs into a compact latent space, a latent diffusion module to model uncertainty, and contrastive learning to align representations. Operating entirely in this latent space, the framework achieves efficient inference while retaining flexible input-output mapping. In addition, we introduce a PDE-informed denoising algorithm based on a variance-preserving diffusion process, which further improves inference efficiency. Extensive experiments on multiple PDE benchmarks demonstrate that Di-BiLPS consistently achieves SOTA performance under extremely sparse inputs (as low as 3%), while substantially reducing computational cost. Moreover, Di-BiLPS enables zero-shot super-resolution, as it allows predictions over continuous spatial-temporal domains.
Zhonghao Li, Chaoyu Liu, Qian Zhang
May 12, 2026cs.GR

Generative Motion In-betweening by Diffusion over Continuous Implicit Representations

Recent advances in generative models have yielded impressive progress on motion in-betweening, allowing for more complex, varied, and realistic motion transitions. However, recent methods still exhibit noticeable limitations in preserving keyframe information and ensuring motion continuity. In this paper, we propose a novel pipeline and sampling optimization strategy for latent diffusion models (LDM) based on motion implicit neural representations (INR). By establishing a mapping between INR and sparse spatial or temporal information within latent diffusion, our model can sample the INR parameters from extremely sparse and ambiguous keyframe data and reconstruct plausible and smooth motions from the manifold. Our experiments demonstrate the superior performance of our model, which significantly improves motion generation quality in scenarios with few keyframes while ensuring both keyframe accuracy and diversity of in-between motions.
Shiyu Fan, Paul Henderson, Edmond S. L. Ho
May 10, 2026cs.AI

Marrying Generative Model of Healthcare Events with Digital Twin of Social Determinants of Health for Disease Reasoning

Despite the central role of sensor-derived measurements such as imaging traits and plasma biomarkers in biomedical research and clinical practice, existing generative models for disease prediction largely depend on event-level representations from hospital and registry data. Given the multi-factorial nature of human disease, the absence of explicit modeling of social determinants of health (SDoH), even in the limited form of ICD-coded proxies (chapters Z and V--Y in ICD-10), limits the capacity for personalized disease modeling and clinical decision support. To address this limitation, we propose a generative model with ICD-coded proxies of SDoH for \textit{in silico} modeling of disease reasoning, a conditioned latent diffusion framework that establishes the connection between multi-organ sensor data with tokenized healthcare events. Specifically, we introduce a novel geometric diffusion model to characterize the temporal evolution of complex data representation such as brain networks (region-to-region connectivity encoded in a graph), in parallel with diffusion models for tabular data from other organ systems. Together, we integrate the generative model with digitalized SDoH proxies (coined \modelname{}) for simulated intervention and reasoning of future disease trajectories. We conduct extensive experiments on the UK Biobank (UKB) dataset, which contains organ-specific imaging traits, including brain (44,834), heart (23,987), liver (28,722), and kidney (32,155), along with nearly 500k medical history sequences (age range: 25\sim89 years). Our \modelname{} achieves significant improvements over state-of-the-art human disease autoregressive models and imaging trait generative baselines.
Ziquan Wei, Tingting Dan, Guorong Wu
May 8, 2026cs.CL

How to Train Your Latent Diffusion Language Model Jointly With the Latent Space

Latent diffusion models offer an attractive alternative to discrete diffusion for non-autoregressive text generation by operating on continuous text representations and denoising entire sequences in parallel. The major challenge in latent diffusion modeling is constructing a suitable latent space. In this work, we present the Latent Diffusion Language Model (LDLM), in which the latent encoder, diffusion model, and decoder are trained jointly. LDLM builds its latent space by reshaping the representations of a pre-trained language model with a trainable encoder, yielding latents that are easy to both denoise and decode into tokens. We show that naive joint training produces a low-quality diffusion model, and propose a simple training recipe consisting of an MSE decoder loss, diffusion-to-encoder warmup, adaptive timestep sampling, and decoder-input noise. Ablations show that each component substantially impacts generation performance. On OpenWebText and LM1B, LDLM achieves better generation performance than existing discrete and continuous diffusion language models while being 2-13×2{\text -}13\times faster, indicating that jointly learning the latent space is a key step toward making latent diffusion competitive for text generation.
Viacheslav Meshchaninov, Alexander Shabalin, Egor Chimbulatov +4
May 8, 2026cs.CV

What Matters for Diffusion-Friendly Latent Manifold? Prior-Aligned Autoencoders for Latent Diffusion

Tokenizers are a crucial component of latent diffusion models, as they define the latent space in which diffusion models operate. However, existing tokenizers are primarily designed to improve reconstruction fidelity or inherit pretrained representations, leaving unclear what kind of latent space is truly friendly for generative modeling. In this paper, we study this question from the perspective of latent manifold organization. By constructing controlled tokenizer variants, we identify three key properties of a diffusion-friendly latent manifold: coherent spatial structure, local manifold continuity, and global manifold semantics. We find that these properties are more consistent with downstream generation quality than reconstruction fidelity. Motivated by this finding, we propose the Prior-Aligned AutoEncoder (PAE), which explicitly shapes the latent manifold instead of leaving diffusion-friendly manifold to emerge indirectly from reconstruction or inheritance. Specifically, PAE leverages refined priors derived from VFMs and perturbation-based regularization to turn spatial structure, local continuity, and global semantics into explicit training objectives. On ImageNet 256x256, PAE improves both training efficiency and generation quality over existing tokenizers, reaching performance comparable to RAE with up to 13x faster convergence under the same training setup and achieving a new state-of-the-art gFID of 1.03. These results highlight the importance of organizing the latent manifold for latent diffusion models.
Zhengrong Yue, Taihang Hu, Mengting Chen +8
May 8, 2026stat.ML

Consistency Regularised Gradient Flows for Inverse Problems

Vision-Language Latent Diffusion Models (LDMs) (Rombach et al., 2022) provide powerful generative priors for inverse problems. However, existing LDM-based inverse solvers typically require a large number of neural function evaluations (NFEs) and backpropagation through large pretrained components, leading to substantial computational costs and, in some cases, degraded reconstruction quality. We propose a unified Euclidean-Wasserstein-2 gradient-flow framework that jointly performs posterior sampling and prompt optimization in the latent space through a single flow that aligns the prior and posterior with the observed data. Combined with few-step latent text-to-image models, this formulation enables low-NFE inference without backpropagation through autoencoders. Experiments across several canonical imaging inverse problems show that our method achieves state-of-the-art performance with significantly reduced computational cost.
Alessio Spagnoletti, Tim Y. J. Wang, Marcelo Pereyra +1
May 6, 2026cs.LG

Deep Dreams Are Made of This: Visualizing Monosemantic Features in Diffusion Models

This paper proposes latent visualization by optimization (LVO), a mechanistic interpretability technique that extends feature visualization by optimization - originally developed for convolutional neural networks - to latent diffusion models. LVO employs sparse autoencoders (SAEs) to disentangle polysemantic layer representations into monosemantic features. Key contributions include latent-space optimization, time-step activity analysis, schedule-matched noise injection, prior initialization through feature steering, and suitable regularization strategies. We demonstrate the method on Stable Diffusion 1.5 fine-tuned on the Style50 dataset, showing that SAE features produce clear visualizations of recognizable concepts - including diagonal compositions, human figures, roses, cables, and waterfall foam - that correlate with dataset examples, while the baseline without disentanglement produces less coherent results. We further show that regularization techniques from pixel-space feature visualization transfer to the latent domain, though they require different configurations for the raw-layer and SAE variants. Compared to dataset examples and steering, LVO provides complementary insights by directly revealing what activates a feature rather than its downstream effects.
Adam Szokalski, Mateusz Modrzejewski
May 5, 2026cs.LG

PODiff: Latent Diffusion in Proper Orthogonal Decomposition Space for Scientific Super-Resolution

Probabilistic super-resolution of high-dimensional spatial fields using diffusion models is often computationally prohibitive due to the cost of operating directly in pixel space. We propose PODiff, a structured conditional generative framework that performs diffusion in a fixed, variance-ordered Proper Orthogonal Decomposition (POD) coefficient space, exploiting the orthogonality of POD modes to impose an interpretable, variance-ordered latent geometry. This design enables efficient ensemble generation, preserves dominant spatial structure, and yields spatially interpretable, well-calibrated uncertainty at substantially lower computational cost. We evaluate PODiff on sea surface temperature downscaling over the West Australian coast and on a controlled advection-diffusion benchmark. PODiff achieves reconstruction accuracy comparable to pixel-space diffusion while requiring significantly less memory and producing more reliable uncertainty estimates than deterministic and Monte Carlo Dropout baselines.
Onkar Jadhav, Tim French, Matthew Rayson +1
May 4, 2026cs.CV

MuCALD-SplitFed: Causal-Latent Diffusion for Privacy-Preserving Multi-Task Split-Federated Medical Image Segmentation

Federated Learning enables decentralized training by aggregating model updates across clients without sharing raw data, while Split Federated Learning further partitions the model between clients and a server to reduce computation and communication at the client side. However, decentralized medical institutions rarely operate on a single shared task, making standard Federated and SplitFed collaborations poorly aligned with real clinical workflows. Multi-task FL extends these frameworks by allowing clients to handle different tasks, but often introduces instability and privacy vulnerabilities. This study proposes \textbf{MuCALD-SplitFed}, a multi-task SplitFed framework that integrates causal representation learning and latent diffusion. Experiments show MuCALD-SplitFed consistently improves segmentation, while baseline SplitFed fails to converge. The proposed approach further reduces information leakage at split points, mitigating reconstruction-based and membership inference attacks. Additionally, MuCALD SplitFed outperforms state-of-the-art personalized FL and multi-task FL approaches. The code repository is: https://github.com/ChamaniS/MuCALD_SplitFed.
Chamani Shiranthika, Hadi Hadizadeh, Parvaneh Saeedi
May 4, 2026cs.CV

Stylistic Attribute Control in Latent Diffusion Models

Text-to-image diffusion models have revolutionized image synthesis and editing, but precise control over stylistic attributes remains a challenge, often causing unintended content modifications. We propose an approach for fine-grained parametric control of stylistic attributes in latent diffusion models by learning disentangled editing directions from synthetic datasets. We use guidance composition to close the domain gap between stylistically finetuned and foundation models, preserving the original image semantics while applying stylistic adjustments. To ensure consistent edits, we introduce a training regularization loss and enhance DDIM inversion with optimized null-conditional embeddings for real image editing. We validate our approach by learning from stylistically filtered synthetic datasets varying a range of stylistic attributes, including outlines, local contrast, watercolorization effects, and geometric patterns. Our evaluations demonstrate that compared to current text-based editing techniques, our method offers well-integrated, more precise and continuously adjustable stylistic modifications.
Max Reimann, Benito Buchheim, Jürgen Döllner
May 1, 2026cs.LG

Learning Multimodal Energy-Based Model with Multimodal Variational Auto-Encoder via MCMC Revision

Energy-based models (EBMs) are a flexible class of deep generative models and are well-suited to capture complex dependencies in multimodal data. However, learning multimodal EBM by maximum likelihood requires Markov Chain Monte Carlo (MCMC) sampling in the joint data space, where noise-initialized Langevin dynamics often mixes poorly and fails to discover coherent inter-modal relationships. Multimodal VAEs have made progress in capturing such inter-modal dependencies by introducing a shared latent generator and a joint inference model. However, both the shared latent generator and joint inference model are parameterized as unimodal Gaussian (or Laplace), which severely limits their ability to approximate the complex structure induced by multimodal data. In this work, we study the learning problem of the multimodal EBM, shared latent generator, and joint inference model. We present a learning framework that effectively interweaves their MLE updates with corresponding MCMC refinements in both the data and latent spaces. Specifically, the generator is learned to produce coherent multimodal samples that serve as strong initial states for EBM sampling, while the inference model is learned to provide informative latent initializations for generator posterior sampling. Together, these two models serve as complementary models that enable effective EBM sampling and learning, yielding realistic and coherent multimodal EBM samples. Extensive experiments demonstrate superior performance for multimodal synthesis quality and coherence compared to various baselines. We conduct various analyses and ablation studies to validate the effectiveness and scalability of the proposed multimodal framework.
Jiali Cui, Zhiqiang Lao, Heather Yu
Apr 30, 2026cs.LG

SPLICE: Latent Diffusion over JEPA Embeddings for Conformal Time-Series Inpainting

Generative models for time-series imputation achieve strong reconstruction accuracy, yet provide no finite-sample reliability guarantees, a critical limitation in power systems where imputed values inform dispatch and planning. We introduce SPLICE (Self-supervised Predictive Latent Inpainting with Conformal Envelopes), a modular framework coupling latent generative imputation with distribution-free, online-adaptive prediction intervals. A JEPA encoder maps daily load segments into a 64-dimensional latent space; a conditional latent bridge with four sampling modes generates candidate gap trajectories; an hourly-conditioned decoder maps back to signal space; and Adaptive Conformal Inference (ACI) wraps the output with coverage-guaranteed prediction bands. The flow-matching variant achieves comparable quality to DDIM in 5--10 ODE steps (5-10x speedup). On thirteen load datasets (nine proprietary, three UCI Electricity, ETTh1), SPLICE achieves the lowest mean Load-only MSE (0.056), winning 9/12 non-degenerate datasets at 91-day gaps and 18/32 across all gap lengths vs. five established baselines, and produces the best CRPS (0.161, -18.3% vs. the strongest competitor). ACI delivers 93--95% empirical coverage, correcting under-coverage failures of up to 7.5 pp observed with static conformal prediction. A pooled JEPA encoder trained on nine feeds transfers to four unseen domains, matching or exceeding per-dataset oracles with only a quick bridge fine-tuning.
Arnaud Zinflou
Apr 26, 2026cs.LG

Learning Interpretable PDE Representations for Generative Reconstructions with Structured Sparsity

Scientific measurements are often bottlenecked by suboptimal conditions, whether that be noise, incomplete spatial coverage, or limited resolution, rendering accurate field reconstruction a difficult task. We introduce LatentPDE, a latent diffusion framework designed to simultaneously resolve sparse-observation reconstruction and super-resolution. While existing physics-guided diffusion models typically rely on soft loss penalties or uninterpretable representations, our approach enforces physical compliance by constructing an inherently interpretable latent space. Specifically, we parameterize the latent variables directly as the coefficients and source terms of an assumed governing PDE. In doing so, LatentPDE is able to reliably reconstruct dynamics across highly disparate and structured data gaps. Empirical results on diverse configurations demonstrate that our model achieves high-fidelity recovery at any desired resolution while also tracking the underlying predictive uncertainty.
Valerie Tsao, Nathaniel Chaney, Manolis Veveakis
Apr 17, 2026cs.CV

CLIMB: Controllable Longitudinal Brain Image Generation using Mamba-based Latent Diffusion Model and Gaussian-aligned Autoencoder

Latent diffusion models have emerged as powerful generative models in medical imaging, enabling the synthesis of high quality brain magnetic resonance imaging scans. In particular, predicting the evolution of a patients brain can aid in early intervention, prognosis, and treatment planning. In this study, we introduce CLIMB, Controllable Longitudinal brain Image generation via state space based latent diffusion model, an advanced framework for modeling temporal changes in brain structure. CLIMB is designed to model the structural evolution of the brain structure over time, utilizing a baseline MRI scan and its acquisition age as foundational inputs. Additionally, multiple conditional variables, including projected age, gender, disease status, genetic information, and brain structure volumes, are incorporated to enhance the temporal modeling of anatomical changes. Unlike existing LDM methods that rely on self attention modules, which effectively capture contextual information from input images but are computationally expensive, our approach leverages state space, a state space model architecture that substantially reduces computational overhead while preserving high-quality image synthesis. Furthermore, we introduce a Gaussian-aligned autoencoder that extracts latent representations conforming to prior distributions without the sampling noise inherent in conventional variational autoencoders. We train and evaluate our proposed model on the Alzheimers Disease Neuroimaging Initiative dataset, consisting of 6,306 MRI scans from 1,390 participants. By comparing generated images with real MRI scans, CLIMB achieves a structural similarity index of 0.9433, demonstrating notable improvements over existing methods.
Duy-Phuong Dao, Muhammad Taqiyuddin, Jahae Kim +4
Jan 23, 2026cs.CV

Semi-Supervised Domain Adaptation with Latent Diffusion for Pathology Image Classification

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image translation, which can distort tissue structures and compromise model accuracy. In this work, we propose a semi-supervised domain adaptation (SSDA) framework that utilizes a latent diffusion model trained on unlabeled data from both the source and target domains to generate morphology-preserving and target-aware synthetic images. By conditioning the diffusion model on foundation model features, cohort identity, and tissue preparation method, we preserve tissue structure in the source domain while introducing target-domain appearance characteristics. The target-aware synthetic images, combined with real, labeled images from the source cohort, are subsequently used to train a downstream classifier, which is then tested on the target cohort. The effectiveness of the proposed SSDA framework is demonstrated on the task of lung adenocarcinoma prognostication. The proposed augmentation yielded substantially better performance on the held-out test set from the target cohort, without degrading source-cohort performance. The approach improved the weighted F1 score on the target-cohort held-out test set from 0.611 to 0.706 and the macro F1 score from 0.641 to 0.716. Our results demonstrate that target-aware diffusion-based synthetic data augmentation provides a promising and effective approach for improving domain generalization in computational pathology.
Tengyue Zhang, Ruiwen Ding, Luoting Zhuang +3
Jan 21, 2026cs.CV

Anatomically Guided Latent Diffusion for Brain MRI Progression Modeling

Accurately modeling longitudinal brain MRI progression is crucial for understanding neurodegenerative diseases and predicting individualized structural changes. Existing state-of-the-art approaches, such as Brain Latent Progression (BrLP), often use multi-stage training pipelines with auxiliary conditioning modules but suffer from architectural complexity, suboptimal use of conditional clinical covariates, and limited guarantees of anatomical consistency. We propose Anatomically Guided Latent Diffusion Model (AG-LDM), a segmentation-guided framework that enforces anatomically consistent progression while substantially simplifying the training pipeline. AG-LDM conditions latent diffusion by directly fusing baseline anatomy, noisy follow-up states, and clinical covariates at the input level, a strategy that avoids auxiliary control networks by learning a unified, end-to-end model that represents both anatomy and progression. A lightweight 3D tissue segmentation model (WarpSeg) provides explicit anatomical supervision during both autoencoder fine-tuning and diffusion model training, ensuring consistent brain tissue boundaries and morphometric fidelity. Experiments on 31,713 ADNI longitudinal pairs and zero-shot evaluation on OASIS-3 demonstrate that AG-LDM matches or surpasses more complex diffusion models, achieving highly competitive image quality and 15-20% reduction in volumetric errors in generated images. AG-LDM also exhibits markedly stronger utilization of temporal and clinical covariates (3.5-31.5x higher covariate sensitivity than BrLP) and generates biologically plausible counterfactual trajectories, accurately capturing hallmarks of Alzheimer's progression such as limbic atrophy and ventricular expansion. These results highlight AG-LDM as an efficient, anatomically grounded framework for reliable brain MRI progression modeling.
Cheng Wan, Bahram Jafrasteh, Ehsan Adeli +2
Dec 16, 2025cs.CV

Elastic3D: Controllable Stereo Video Conversion with Guided Latent Decoding

The growing demand for immersive 3D content calls for automated monocular-to-stereo video conversion. We present Elastic3D, a controllable, direct end-to-end method for upgrading a conventional video to a binocular one. Our approach, based on (conditional) latent diffusion, avoids artifacts due to explicit depth estimation and warping. The key to its high-quality stereo video output is a novel, guided VAE decoder that ensures sharp and epipolar-consistent stereo video output. Moreover, our method gives the user control over the strength of the stereo effect (more precisely, the disparity range) at inference time, via an intuitive, scalar tuning knob. Experiments on three different datasets of real-world stereo videos show that our method outperforms both traditional warping-based and recent warping-free baselines and sets a new standard for reliable, controllable stereo video conversion. Please check the project page for the video samples https://elastic3d.github.io.
Nando Metzger, Prune Truong, Goutam Bhat +2
Dec 5, 2025cs.CV

Delving into Latent Spectral Biasing of Video VAEs for Superior Diffusability

Latent diffusion models pair VAEs with diffusion backbones, and the structure of VAE latents strongly influences the difficulty of diffusion training. However, existing video VAEs typically focus on reconstruction fidelity, overlooking latent structure. We present a statistical analysis of video VAE latent spaces and identify two spectral properties essential for diffusion training: a spatio-temporal frequency spectrum biased toward low frequencies, and a channel-wise eigenspectrum dominated by a few modes. To induce these properties, we propose two lightweight, backbone-agnostic regularizers: Local Correlation Regularization and Latent Masked Reconstruction. Experiments show that our Spectral-Structured VAE (SSVAE) achieves a 3×3\times speedup in text-to-video generation convergence and a 10% gain in video reward, outperforming strong open-source VAEs. The code is available at https://github.com/zai-org/SSVAE.
Shizhan Liu, Xinran Deng, Zhuoyi Yang +3
Dec 1, 2025cs.LG

Weight Space Representation Learning via Neural Field Adaptation

We investigate the potential of weights to serve as effective representations, focusing on neural fields. Our key insight is that constraining the optimization space through a pre-trained base model and low-rank adaptation (LoRA) can induce structure in weight space. Across reconstruction, generation, and analysis tasks on 2D and 3D data, we find that multiplicative LoRA weights achieve high representation quality while exhibiting distinctiveness and semantic structure. When used with latent diffusion models, multiplicative LoRA weights enable higher-quality generation than existing weight-space methods.
Zhuoqian Yang, Mathieu Salzmann, Sabine Süsstrunk
Dec 1, 2025cs.CV

Diffusion Model in Latent Space for Medical Image Segmentation Task

Medical image segmentation is crucial for clinical diagnosis and treatment planning. Traditional methods typically produce a single segmentation mask, failing to capture inherent uncertainty. Recent generative models enable the creation of multiple plausible masks per image, mimicking the collaborative interpretation of several clinicians. However, these approaches remain computationally heavy. We propose MedSegLatDiff, a diffusion based framework that combines a variational autoencoder (VAE) with a latent diffusion model for efficient medical image segmentation. The VAE compresses the input into a low dimensional latent space, reducing noise and accelerating training, while the diffusion process operates directly in this compact representation. We further replace the conventional MSE loss with weighted cross entropy in the VAE mask reconstruction path to better preserve tiny structures such as small nodules. MedSegLatDiff is evaluated on ISIC-2018 (skin lesions), CVC-Clinic (polyps), and LIDC-IDRI (lung nodules). It achieves state of the art or highly competitive Dice and IoU scores while simultaneously generating diverse segmentation hypotheses and confidence maps. This provides enhanced interpretability and reliability compared to deterministic baselines, making the model particularly suitable for clinical deployment.
Ngoc Huynh Trinh, Hai Toan Nguyen, Son Ba Luong +1
Nov 7, 2025cs.SD

Perceptually Aligning Representations of Music via Noise-Augmented Autoencoders

We argue that training autoencoders to reconstruct inputs from noised versions of their encodings, when combined with perceptually motivated losses, yields encodings that are structured according to a perceptual hierarchy. We demonstrate the emergence of this hierarchy by showing that, after training an audio autoencoder in this manner, perceptually salient information is captured in coarser representation structures than with conventional training. Furthermore, we show that such perceptual hierarchies improve latent diffusion decoding in the context of estimating pitch surprisal in music and predicting EEG-brain responses to music listening. In both cases, our results surpass those of previous methods. Pretrained weights are available on github.com/CPJKU/pa-audioic.
Mathias Rose Bjare, Giorgia Cantisani, Marco Pasini +2
Sep 23, 2025stat.ML

A Gradient Flow Approach to Solving Inverse Problems with Latent Diffusion Models

Solving ill-posed inverse problems requires powerful and flexible priors. We propose leveraging pretrained latent diffusion models for this task through a new training-free approach, termed Diffusion-regularized Wasserstein Gradient Flow (DWGF). Specifically, we formulate the posterior sampling problem as a Wasserstein gradient flow in the latent space of an expected negative log posterior objective, regularized by a Kullback-Leibler divergence to the diffusion prior. We demonstrate the performance of our method on standard benchmarks using StableDiffusion (Rombach et al., 2022) as the prior.
Tim Y. J. Wang, O. Deniz Akyildiz
Aug 28, 2025cs.LG

EEGDM: Learning EEG Representation with Latent Diffusion Model

Recent advances in self-supervised learning for EEG representation have largely relied on masked reconstruction, where models are trained to recover randomly masked signal segments. While effective at modeling local dependencies, the training objective of masked reconstruction does not compel the model to capture global generative constraints essential for characterizing neural activity. To address this limitation, we propose EEGDM, a novel self-supervised framework that leverages latent diffusion models to generate EEG signals as an objective. Unlike masked reconstruction, diffusion-based generation progressively denoises signals from noise to realism, compelling the model to capture holistic temporal patterns and cross-channel relationships. Specifically, EEGDM incorporates an EEG encoder that distills raw signals and their channel augmentations into a compact representation, which serves as conditional information to guide the diffusion denoising process, thereby enabling the encoder and diffusion model to be jointly optimized through the generative objective. This design endows EEGDM with a compact latent space, which not only offers ample control over the generative process but also can be leveraged for downstream tasks. Experimental results show that EEGDM (1) reconstructs high-quality EEG signals, (2) learns robust representations, and (3) achieves competitive performance across diverse downstream tasks, thus exploring a new direction for self-supervised EEG representation learning.
Shaocong Wang, Tong Liu, Yihan Li +6
Mar 30, 2025cs.CV

TraceMark-LDM: Authenticatable Watermarking for Latent Diffusion Models via Binary-Guided Rearrangement

Image generation algorithms are increasingly integral to diverse aspects of human society, driven by their practical applications. However, insufficient oversight in artificial Intelligence generated content (AIGC) can facilitate the spread of malicious content and increase the risk of copyright infringement. Among the diverse range of image generation models, the Latent Diffusion Model (LDM) is currently the most widely used, dominating the majority of the Text-to-Image model market. Currently, most attribution methods for LDMs rely on directly embedding watermarks into the generated images or their intermediate noise, a practice that compromises both the quality and the robustness of the generated content. To address these limitations, we introduce TraceMark-LDM, an novel algorithm that integrates watermarking to attribute generated images while guaranteeing non-destructive performance. Unlike current methods, TraceMark-LDM leverages watermarks as guidance to rearrange random variables sampled from a Gaussian distribution. To mitigate potential deviations caused by inversion errors, the small absolute elements are grouped and rearranged. Additionally, we fine-tune the LDM encoder to enhance the robustness of the watermark. Experimental results show that images synthesized using TraceMark-LDM exhibit superior quality and attribution accuracy compared to state-of-the-art (SOTA) techniques. Notably, TraceMark-LDM demonstrates exceptional robustness against various common attack methods, consistently outperforming SOTA methods.
Wenhao Luo, Zhangyi Shen, Ye Yao +3
Nov 16, 2024cs.CV

C-DiffSET: Leveraging Latent Diffusion for SAR-to-EO Image Translation with Confidence-Guided Reliable Object Generation

Synthetic Aperture Radar (SAR) imagery provides robust environmental and temporal coverage (e.g., during clouds, seasons, day-night cycles), yet its noise and unique structural patterns pose interpretation challenges, especially for non-experts. SAR-to-EO (Electro-Optical) image translation (SET) has emerged to make SAR images more perceptually interpretable. However, traditional approaches trained from scratch on limited SAR-EO datasets are prone to overfitting. To address these challenges, we introduce Confidence Diffusion for SAR-to-EO Translation, called C-DiffSET, a framework leveraging pretrained Latent Diffusion Model (LDM) extensively trained on natural images, thus enabling effective adaptation to the EO domain. Remarkably, we find that the pretrained VAE encoder aligns SAR and EO images in the same latent space, even with varying noise levels in SAR inputs. To further improve pixel-wise fidelity for SET, we propose a confidence-guided diffusion (C-Diff) loss that mitigates artifacts from temporal discrepancies, such as appearing or disappearing objects, thereby enhancing structural accuracy. C-DiffSET achieves state-of-the-art (SOTA) results on multiple datasets, significantly outperforming the very recent image-to-image translation methods and SET methods with large margins.
Jeonghyeok Do, Jaehyup Lee, Munchurl Kim
Sep 1, 2024cs.CV

Zero-Shot Paragraph-level Handwriting Imitation with Latent Diffusion Models

The imitation of cursive handwriting is mainly limited to generating handwritten words or lines. Multiple synthetic outputs must be stitched together to create paragraphs or whole pages, whereby consistency and layout information are lost. To close this gap, we propose a method for imitating handwriting at the paragraph level that also works for unseen writing styles. Therefore, we introduce a modified latent diffusion model that enriches the encoder-decoder mechanism with specialized loss functions that explicitly preserve the style and content. We enhance the attention mechanism of the diffusion model with adaptive 2D positional encoding and the conditioning mechanism to work with two modalities simultaneously: a style image and the target text. This significantly improves the realism of the generated handwriting. We set a new benchmark in our comprehensive evaluation, achieving 61 % mAP and 56 % top-1 accuracy in style preservation, significantly outperforming the previous best method (37 % mAP, 30 % top-1). We are making our code publicly available for reproducibility, supporting research in this area and research into potential countermeasures: https://github.com/M4rt1nM4yr/paragraph_handwriting_imitation_ldm
Martin Mayr, Marcel Dreier, Florian Kordon +5
Date pendingcs.CV

Reconstruction of a 3D wireframe from a single line drawing via generative depth estimation

Reconstructing 3D geometry from 2D engineering line drawings is an inherently ambiguous problem: while visible strokes determine the object's projected structure, they do not specify the depth of each stroke. Rather than treating this problem as sketch-based asset generation, where models often infer unobserved structure, we study projection-faithful wireframe reconstruction: lifting a user-provided drawing into 3D according to its visible strokes. We formulate this task as conditional depth estimation over line drawings, predicting a depth value for each drawn pixel to produce a 3D wireframe. To model the ambiguities of orthographic projection, we implement a Latent Diffusion Model with spatial conditioning on the input sketch and optional partial-depth conditioning for iterative reconstruction. We train and evaluate our models on over three million synthetic image-depth pairs derived from CAD wireframes, including a newly curated corpus of roughly 90,000 shapes. Across varying shape complexities, our framework achieves robust reconstruction performance; scaling from 256 to 512 resolution with a retrained latent space roughly halves reconstruction error, reaching a 3.9% best-of-five (7.0% average) normalized depth error. These results demonstrate the potential of projection-faithful depth estimation as a user-controlled approach for iterative 3D wireframe creation in engineering design.
Elton Cao, Hod Lipson