Latent Diffusion Model

Multimodal reasoning requires models to draw on information from multiple modalities throughout the reasoning process. Yet existing methods often concatenate modality-specific thought tokens in a single sequence, leaving the model to bridge representational differences as it reasons across modalities. We introduce Uni-LaDiR (Unified Latent Diffusion Reasoner), a framework that brings these thoughts into a shared latent space for reasoning. A unified encoder maps teacher reasoning steps from different modalities into shared thought tokens, trained to preserve the information needed for later reasoning steps and the final answer or action. Because the same context can support multiple valid next steps, we use diffusion to predict the next block of thought tokens from the input and preceding blocks. Jointly training the encoder and diffusion reasoner with shared model weights encourages thought tokens to be both useful for the task and predictable from the available context. At inference, the model generates these tokens without teacher observations. Across eleven vision-language model (VLM) benchmarks and two vision-language-action (VLA) suites, Uni-LaDiR achieves relative gains over the strongest evaluated baselines of 7.3% on visual reasoning tasks and 6.1% on robot manipulation tasks.

3D Foundation Models (3DFMs) such as VGGT have recently pushed the boundaries of 3D vision by predicting rich unified representations with feed-foward transformers. The scene representations learned by these models enable strong performance on multiple 3D vision tasks. In this paper, we investigate using their internal representations to infer 3D in the scene from new views. Our hypothesis is that in order to solve the task of 3D reconstruction, these models need to learn a representation that includes a large amount of general knowledge about 3D scenes. After showing that it is possible to decode hidden surfaces from internal 3DFM representations, we propose a method, Z3D, that estimates pointmaps in unseen views by doing latent diffusion on 3DFM representation. We show that Z3D can predict realistic depth maps for new views across multiple datasets.

Text-to-image generative models have advanced rapidly, with modern Diffusion Transformer architectures producing images that are increasingly difficult to distinguish from human-created artwork. This development has raised significant concerns regarding copyright protection, misinformation, fraud, impersonation, and the authenticity of digital content. Most AI-art detectors are trained and evaluated on the same generator family, leaving robustness to newer architectures underexplored. In this chapter, we analyze generator shift based on a Stable Diffusion 3.5 Medium (SD3.5m) artwork dataset spanning ten art styles through reverse prompting of held-out human artwork samples. Five detectors are trained on U-Net-based latent diffusion artwork and evaluated in a zero-shot cross-generator setting on the SD3.5m dataset. Deep learning models perform strongly in-distribution but degrade under generator shift, misclassifying many SD3.5m images as human while human false positives remain low. The CLIP ViT-L/14 model performs best overall, while Grad-CAM analysis reveals weaker and more diffuse activation on false negatives. These findings highlight a generalization gap in current AI-art detectors and motivate the development of detectors as one component of a layered defense that remains reliable across rapidly evolving generative architectures.

4D generation synthesizes dynamic 3D scenes from conditions such as text or images. Existing methods either reconstruct generated RGB videos with a separate 4D model or adapt a particular video generator to predict geometry directly. The former suffers from distribution mismatch and error propagation, whereas the latter ties 4D prediction to a specific generator and may require retraining when the generator or conditioning regime changes. We ask whether the final denoised latents of video models that share a variational autoencoder (VAE) can instead provide a reusable interface to explicit 4D prediction. Building on this insight, we introduce direct latent-to-4D generation and instantiate it as Latent-to-4D, which bypasses RGB by aligning a video latent with the token grid of a pretrained 4D decoder and refining it through frame-wise and global spatiotemporal attention. Trained on roughly 1K existing reconstruction clips, a single checkpoint transfers unchanged across multiple video diffusion transformers within the same VAE family. On Text4D-200 and I4D-200, Latent-to-4D surpasses matched same-latent Wan+4RC cascades in projection-based DINO-F1 by 2.88--3.45 and 5.81 points, respectively, while also being preferred by human raters for geometry, temporal stability, and overall quality.

Large Language Models (LLMs) deployed as AI agents frequently exhibit user specification-grounding failures, executing hallucinated, undesired actions to force a resolution rather than expressing uncertainty. Existing detection methods fail to provide actionable, real-time correction as they either do not localize the hallucinations, or incur prohibitive inference latency. We introduce the Latent Critic, a lightweight low-rank adapter (LoRA) that operates concurrently with a frozen base LLM's generation to actively restructure the transformer's residual stream---amplifying latent grounding signals and translating them into localized, natural language feedback within a single sequence. By refining the base model's native uncertainty signals, this manipulation of the latent space enables reliable, granular detection without the overhead of secondary inference loops. Mechanistic analysis via activation patching and layer-wise probing shows that this rank-invariant behavior restructures pre-existing uncertainty geometry into a linearly separable representation that transfers more reliably than base model representations alone. Using tool-calling as an instantiation of granular hallucinations, we validate the detection and downstream improvements enabled by the Latent Critic architecture across Qwen and Llama-based models. Demonstrating superior real-time efficacy, our approach significantly outperforms equivalent-scale fine-tuned external detectors, semantic entropy baselines, and passive internal probes in isolating hallucinations, achieving 0.966 AUROC and >80% accuracy in localization (e.g., ungrounded: date). When deployed in a closed-loop ReAct environment, the Critic acts as a negligible latency guardrail, intercepting hallucinations before execution to prevent undesired actions while simultaneously leveraging this specific localized feedback to enable efficient agent self-correction.

The proliferation of AI-generated images produced by Latent Diffusion Models (LDMs) has raised critical concerns regarding copyright infringement and misinformation. Although existing frequency-domain watermarking methods embed handcrafted geometric patterns into the initial latent noise prior to generation, they suffer from limited capacity and rigid pattern designs. We propose DeepFreqMark, an end-to-end learnable frequency-domain watermarking framework that replaces manual pattern engineering with a neural message encoder and decoder. To circumvent the computational bottleneck caused by Denoising Diffusion Implicit Model (DDIM) inversion during training, we introduce a Spherical Linear Interpolation (Slerp)-based attack simulation. This approach operates directly on the noise latent while strictly preserving the Gaussian variance. Extensive experiments demonstrate that DeepFreqMark achieves significantly lower Bit Error Rates (BER) than baseline methods under real-world attacks and scales to 256 bits message capacity. Our source code is available at https://github.com/chenhsiu48/DeepFreqMark.

Visible-to-infrared image translation provides a practical way to expand infrared training data using abundant visible images. Diffusion models are promising for this task because of their strong generative performance. However, existing diffusion-based methods typically use semantic priors only as external conditions, without explicitly regulating token interactions within the denoising network. Consequently, they struggle to preserve object locations, shapes, and semantic layouts required for reliable annotation reuse. We propose SC-Diff, a semantically calibrated latent diffusion framework that uses semantic priors for both conditional guidance and internal self-attention calibration. A pretrained SAM3 model with predefined text prompts first extracts category-specific semantic masks from visible images. These masks are merged into a semantic map and fused with the visible image as the input condition. The same map is converted into token-level semantic labels to calibrate self-attention in the denoising network. Based on these labels, we introduce Semantic-Guided Self-Attention Calibration (SGSC), which adaptively applies positive biases to query-key pairs of the same category. The query-wise calibration strength depends on the dispersion of attention across semantic categories and the attention assigned to the query's own category. The original attention scores further modulate the bias, giving greater calibration to same-category keys with stronger responses. This soft calibration reduces cross-category interference while retaining global contextual interactions, thereby improving semantic consistency in generated infrared images. Extensive experiments show that SC-Diff improves perceptual quality and produces more effective synthetic training data for downstream infrared object detection.

Brain magnetic resonance imaging (MRI) is central to neuroscience and clinical assessment, but models are commonly developed for individual diseases, populations or imaging protocols. Foundation models promise more general representations, yet they are usually pretrained once and can lose earlier capabilities when updated with new data. Here we show that Alcmaeon, a three-dimensional brain MRI foundation model pretrained without manual labels on more than 425,000 volumes and derived imaging maps, can be expanded sequentially across clinical domains. Alcmaeon combines volumetric encoding and latent diffusion generation with Graph-Blueprint Pruning (GBP), which protects network modules important to earlier domains while leaving the remaining capacity trainable. Across expansion from healthy ageing and neurodegeneration to developmental, psychiatric and tumour imaging, GBP showed less forgetting than sequential adaptation and elastic weight consolidation across voxel-level reconstruction measures, with its largest advantage after adaptation to tumour imaging. The blueprints provided an inspectable record of how model capacity was protected and reused. Representations from different model levels supported image synthesis, disease classification, survival modelling and postoperative prediction, although no single representation was optimal for every task. These findings provide a route towards brain MRI foundation models that can grow with emerging data while retaining earlier capabilities.

In this technical report, I present a new method for guiding image generation in the context of Virtual- Try-On (VITON). The proposed method leverages new open source Ai models to augment the image data with labels, such as lengths and styles. By training adapters with these labels paired with images of the garments, the model can produce a more diverse set of images that the user can control. For the end user, such as a retailer, this means that they can assure that the produced image is as true to the true fit as possible, not misleading consumers

We introduce the Intrinsic Hybrid Latent Diffusion Model (ILDM), a generative framework that integrates probabilistic dimensionality reduction with geometry-aware diffusion on unknown manifolds. While diffusion models (DMs) have achieved state-of-the-art results in high-dimensional data synthesis, they rely on large training datasets and ignore intrinsic geometric structure. Latent diffusion models (LDMs) address the high dimensionality by learning a latent space, but they typically impose a Euclidean structure, failing to capture the underlying manifold geometry, especially problematic in data-sparse regimes. ILDM addresses these limitations by interpreting the latent space as a chart of an unknown Riemannian manifold, with geometry and uncertainty quantified through a probabilistic decoder. The forward process is a hybrid diffusion that switches between Riemannian and Euclidean dynamics based on local uncertainty, where the Riemannian component is governed by a probabilistic metric tensor derived from the decoder. To learn the generative dynamics, we introduce an approximate denoising score matching method tailored to the hybrid diffusion setting, enabling a backward process defined by hybrid Langevin dynamics. Experiments on COIL-100, MNIST, and cardiac MRI datasets demonstrate that ILDM significantly improves generation quality, achieving lower FID and LPIPS scores compared to standard diffusion and latent diffusion models.

Text-controlled symbolic music generation has recently gained research attention due to its versatile, flexible and straightforward approach to music composition. However, previous approaches tend to generate symbolic music with compromising quality, diversity, controllability and limited duration. In this paper, we present Diff-Symbo, an innovative method that uses latent diffusion model (LDM) to generate high-quality, diverse and long-duration symbolic music. To address the lack of text-symbolic music dataset, we develop a comprehensive dataset with 19,345 text templates by employing large language model. Furthermore, we design a music information encoder to reduce the training overhead while extracting more effective control representations. Given textual descriptions, our proposed method leverages LDM to improve the quality and diversity of music generation. Our method also improves the duration and the compositional consistency of music generation through an autoregressive approach. Experimental results show significant improvements of Diff-Symbo in text controllability, duration, and the quality of generated music compared to the baseline models such as GPT-4, MuseCoco and Multitrack Music Transformer (MMT). As one of the pioneer models in this field, Diff-Symbo paves the way towards controllable and high-quality symbolic music composition based on LDM, offering valuable contributions to both music amateurs and practitioners.

Automatic Drum Transcription (ADT) is commonly formulated as a direct mapping from a music mixture to symbolic drum events. While effective for transcription, this formulation discards the acoustic stems that are useful for editing, remixing, and production. We revisit an alternative separate-and-detect formulation, where a drum source separation front end first produces five editable drum stems, and a fixed onset detector then converts each stem into symbolic events. The separator is built on a five-stem latent diffusion model that jointly generates kick, snare, toms, hi-hats, and cymbals in a compact VAE latent space. We further study two training-only auxiliary branches--an onset branch (OB) and a timbre branch (TB)--which shape the separator during learning but are discarded at inference. Trained on synthetic drum multitracks and evaluated on MDB Drums and ENST-Drums, the proposed pipeline consistently improves over a strong U-Net-based drum separation baseline in overall transcription F1. It also outperforms a representative end-to-end ADT system on kick and snare F1 under our evaluation protocol, while additionally providing separated audio stems. The ablation results show that OB gives the most stable transcription gains, whereas TB changes the trade-off between reconstruction, acoustic stem quality, and onset detection. These results suggest that generative drum demixing can serve not only as a source separation model, but also as a practical front end for interpretable drum transcription.

Although semantic watermarking is considered a promising safeguard for images generated by Latent Diffusion Models (LDMs), the reliance of the watermark detection pipeline on neural networks introduces a critical yet underexplored backdoor attack surface. To systematically study this vulnerability, we propose GhostVAE to plant a stealthy backdoor into the encoder of Variational Autoencoder (VAE), enabling reliable evasion of watermark detection. GhostVAE operates in two stages: it first constructs a universal trigger via power spectrum regularization to improve the trigger robustness, and then trains a backdoored VAE encoder with a parameter-aligned objective. Through extensive evaluations across three state-of-the-art semantic watermarking schemes and three widely adopted LDMs, we show that GhostVAE preserves watermark detection performance on benign images (achieving an average true positive rate of 94.4%), while simultaneously enabling highly effective evasion under trigger activation (achieving an average attack success rate of 94.6%). Moreover, we comprehensively analyze seventeen representative defenses and demonstrate that GhostVAE remains stealthy across the input space, parameter space, and latent space. Our work fundamentally undermines the trustworthiness of semantic watermarking systems and highlights that secure deployment of semantic watermarks requires end-to-end security considerations, particularly for neural network components.

Facial biometric identification relies on the distinctiveness of user attributes within a high-dimensional embedding space. However, the decision boundaries of deep face recognition (FR) systems are often sufficiently narrow that they can be conflated, rendering the models vulnerable to adversarial attacks. In such scenarios, the FR system fails to distinguish between an authentic source and a meticulously crafted adversarial face. Existing adversarial methods targeting facial biometrics are limited in both performance and their ability to generate high-quality images that are imperceptible to humans. Moreover, these methods often fail when the source and target images belong to different demographic groups or genders. To address these limitations, we present a novel approach for adversarial face generation via latent-space optimization. We leverage latent diffusion models directly to guide generation toward target identity embeddings, as measured by a face recognition model. Our proposed \textbf{DiffAttack} framework has been evaluated on standard benchmarks, such as the FFHQ and CelebA-HQ datasets. DiffAttack significantly outperforms existing adversarial techniques, achieving a high average attack success rate of 84.86% across multiple face recognition models (e.g., FaceNet). Notably, DiffAttack demonstrates superior transferability, surpassing traditional noise-based methods by over 15.28% and semantic-based approaches by approximately 5.21% on benchmark datasets like FFHQ and CelebA-HQ.

Editing character motion often requires transferring a gesture or gait from one or more reference motions while preserving the source action, timing, root trajectory, and unselected body regions. Existing motion datasets, however, rarely provide paired targets for arbitrary part-local content--reference combinations, and self-reconstruction training may allow a diffusion model to reproduce the content motion while underusing the routed reference. We present MoSAIC, a latent diffusion framework for part-local reference-conditioned motion style transfer. MoSAIC factorizes content and reference features by anatomical region, preserves the root trajectory through a separate conditioning pathway, and routes user-selected references to individual body parts. Its central contribution is aligned intervention supervision, which constructs synchronized references and counterfactual targets through controlled local transformations, making both the requested regional response and the motion to be preserved directly observable during training. In a frozen evaluation comprising 128 motions and 896 routed conditions, part-masked routing reduces preserved-region error from 70.64 to 66.45mm and matched-noise off-target leakage from 18.08 to 9.88mm relative to whole-body routing, while retaining a positive selected-region response. A matched-budget continuation study further shows that retaining aligned intervention supervision produces an 8.8% relative increase in selected-target response and a 2.0-percentage-point increase in requested-route influence concentration. These results demonstrate that MoSAIC improves the response--preservation trade-off required for selective and controllable part-local motion editing.

High-fidelity 3D generative modeling increasingly relies on the latent diffusion paradigm, where the reconstruction quality of the underlying 3D VAE becomes a primary bottleneck. Existing approaches largely follow two paradigms: sparse voxel-based representations achieve strong reconstruction quality but incur significant memory and computational overhead, while set-based representations are compact and continuous yet typically lag in fidelity due to latent sparsity and excessive global smoothness. We propose MSVS-VAE, a hierarchical set-based VAE that closes this fidelity gap without sacrificing compactness. Our key idea is to progressively densify anchored VecSet latents via hierarchical point-shuffle upsampling, increasing spatial capacity for fine-grained geometry modeling. To efficiently decode from the densified hierarchy, we replace global cross-attention with AVS-Conv, a geometry-aware local aggregation operator operating within local neighborhoods rather than the exhaustive latent set. We further introduce multi-scale query decoding to fuse coarse-to-fine latent features, where coarse scales provide stable global context, and fine scales refine localized geometry, reducing artifacts from overly local receptive fields. Extensive experiments on Objaverse, ABO, and in-the-wild benchmarks demonstrate that MSVS-VAE consistently outperforms prior set-based and voxel-based VAEs, delivering approximately 10x faster decoding than prior set-based methods and approximately 10x higher compactness than voxel-based baselines.

Mobile infrared-visible imaging typically pairs a compact infrared sensor with a high-resolution visible camera for complementary perception. While cross-sensor misalignment caused by different optics, viewpoints, fields of view, and exposure timings hinders practical deployment. In this paper, we propose BeyondFusion, a unified latent diffusion framework for calibration-free visible-guided infrared super-resolution and infrared-visible fusion tasks. The proposed framework supports both task-specific training and joint training where two tasks are optimized and executed as two readouts of the same generative process. Instead of relying on explicit registration or geometric warping, BeyondFusion introduces a cross-modal self-aligning (CMSA) module into the denoising U-Net. CMSA reorganizes infrared and visible latent tokens into a shared attention space to learn content-adaptive cross-modal correspondence during the denoising process. Together with misalignment augmentation module, the model is facilitated to exploit visible structural and semantic cues while preserving thermal consistency, enabling high-frequency infrared reconstruction and informative fused-image generation under uncalibrated conditions. Extensive experiments on public benchmarks and a mobile infrared-visible imaging system show strong performance across aligned inputs, low-resolution infrared observations, synthetic misalignments, and real mobile captures with unsynchronized sensors. Ablation studies, unified training analysis, and downstream pedestrian detection further validate the effectiveness of BeyondFusion for calibration-free multimodal imaging.

Diffusion models typically suffer from error accumulation during iterative sampling, commonly referred to as exposure bias. We reveal systematic frequency-dependent discrepancies between training and inference, which can be interpreted as frequency-dependent SNR error. Crucially, the direction of this mismatch varies across models and timesteps, indicating that fixed correction rules do not generalize. We propose Spectral Alignment (SPA), a lightweight, guidance-based method that calibrates the power spectrum of intermediate predictions to a pre-computed prior. Our approach consists of two stages: (1) offline fitting of a parametric spectrum model from training data, and (2) inference-time guidance via efficient FFT-based gradient computation. SPA introduces minimal computational overhead (3-4%) and is complementary to Classifier-Free Guidance (CFG). We demonstrate consistent improvements across diverse architectures, from pixel-space models (DDPM, ADM) to latent diffusion models (SD2.0, SDXL) and flow-matching models (SD3.5, FLUX). Our implementation is available at https://github.com/SonyResearch/SPA.

Image inpainting aims to reconstruct missing or corrupted regions of an image while preserving as much as possible, visual and semantic consistency. In medical imaging, this task is particularly important because artifacts, missing information, and pathological alterations can compromise diagnostic reliability and downstream clinical applications. Recently, diffusion models have emerged as state-of-the-art generative approaches for medical image inpainting due to their ability to generate anatomically consistent reconstructions. This survey presents a systematic review of diffusion-based methods for medical image inpainting, covering the main architectures, applications, datasets, and evaluation strategies reported across 60 studies. In addition, we propose a taxonomy for diffusion-based approaches. The analysis reveals a rapid growth of research interest in diffusion-based medical image inpainting, with denoising diffusion probabilistic models and latent diffusion models emerging as the dominant architectures. The reviewed studies mainly focus on artifact removal, data augmentation, pseudo-healthy tissue reconstruction, and anomaly detection, particularly in magnetic resonance imaging and computed tomography imaging. Overall, diffusion models demonstrate strong performance in producing anatomically plausible reconstructions and aiding downstream clinical tasks. However, the review also highlights important challenges, including the lack of standardized benchmarks, limited dataset diversity, and restricted validation procedures across diverse clinical applications and imaging scenarios.

Reliable perception under diverse weather conditions remains a major challenge for autonomous driving systems. A common strategy to improve robustness is either to synthesize adverse weather conditions for training perception models or to apply weather-removal techniques to recover clean inputs. However, existing approaches typically rely on synthetic data augmentation or physics-based, task-specific models that require paired training data and often struggle to generate realistic weather effects or generalize robustly to out-of-domain scenarios. Toward this problem, we present Cyclone, a unified framework for weather editing based on latent diffusion, equipped with cycle-consistent constraints and knowledge from image-text models. Cyclone enables the generation of multiple weather conditions across diverse scenes while eliminating the need for paired data. Experimental results show that our approach produces more realistic, structure-preserving outputs than existing baselines and leads to consistent improvements across several downstream driving perception tasks. Furthermore, we demonstrate that Cyclone can be distilled to a video diffusion model for temporally consistent weather editing.

Existing Stochastic 3D Human Motion Prediction models are fundamentally constrained by hard-coding the skeleton kinematics, severely limiting generalization, preventing cross-dataset training, and requiring complex data retargeting. We introduce EquiFusion, the first kinematics-agnostic model to solve this bottleneck, implementing a latent diffusion model with a permutation equivariant architecture. EquiFusion treats the kinematics' connectivity as an explicit input parameter, ensuring its internal computations are inherently agnostic to joint ordering and graph structure. This novel design enables truly cross-dataset generalization to unseen kinematics and unlocks novel zero-shot directions, such as motion prediction from partial or occluded observations and targeted limb generation. EquiFusion achieves state-of-the-art results on major benchmarks, being up to 75% more compact than previous kinematics-specific methods, while achieving faster training and inference. EquiFusion thus establishes a new, flexible standard for robust human motion prediction. Model and training code are available at https://ceveloper.github.io/publications/equifusion/.

Recent diffusion-based generative models have shown impressive performance in image generation and editing. However, due to memory limitations and the high cost of collecting high-resolution training images, existing methods are typically restricted to inputs with linear resolutions below 1K. In contrast, photos captured by modern mobile devices often reach linear resolutions up to 8K, revealing a significant gap between current capabilities and real-world demands. Simply upscaling low-resolution edited results often results in visually enlarged but blurry images that lack fine details. This paper introduces UltraDiffEdit, a novel, tuning-free image editing framework that extends off-the-shelf latent diffusion models (LDMs) to ultrahigh resolutions. UltraDiffEdit employs a multi-scale progressive editing strategy, iteratively blending high-resolution edited content with unedited areas in a coarse-to-fine manner. We employ multi-patch encoding to preserve both edited and unedited visual details within the latent space. To mitigate editing artifacts, our global-local consistency denoising technique consistently integrates edited and unedited latent features, ensuring smooth transition at editing boundaries from the latent representation to the final image. We also introduce a patch-based hybrid sampling approach that captures local, intermediate, and global features, ensuring semantic coherence and enhancing fine detail during denoising. We conduct extensive experiments demonstrating UltraDiffEdit's superior editing quality and flexibility: it can handle image resolutions up to 8K using only a single NVIDIA GeForce RTX 3090 GPU. The source code is publicly available at https://github.com/LonglongaaaGo/UltraDiffEdit.

We introduce the first multiplayer world model for highly dynamic environments governed by complex physical interactions. Whereas single-player world models treat the other agents as part of the environment, ours conditions on the action streams of multiple agents, learning to attribute changes in the scene to the correct player and to stay coherent under arbitrary combinations of their actions. We study this problem in the game of Rocket League, where players compete and cooperate under fast, tightly coupled dynamics. Trained on 10,000 hours of gameplay collected with publicly available bots, our 5-billion-parameter latent diffusion model generates four-player matches in real time, producing 20 frames per second on a single Nvidia B200 GPU. Although trained only on short clips, its rollouts stay stable far beyond the training horizon: distributional quality holds steady out to five minutes, the longest horizon we measure, and in practice we observe rollouts continuing for hours with no sign of collapse. We systematically investigate the central design choices: the video codec, the generative objective, and the multiplayer conditioning scheme. In addition, we characterize how behavior changes with model and data scale, including the capabilities that emerge and the failure modes that persist. We further develop targeted evaluations that probe the model's physical understanding rather than visual appearance alone. To support continued research on multiplayer world models, we release our dataset, our full training and inference codebase, and a live demo.

Controllable generative models of 3D medical images can synthesize volumes with specified clinical attributes, but this demands samples that are simultaneously high-fidelity, natively 3D, and faithful to the requested conditioning. We present CONFLUX, a latent diffusion model for chest computed tomography (CT): a 3D variational autoencoder compresses each volume, and a rectified-flow transformer generates in the latent space. Generation is conditioned on structured radiological metadata (18 abnormality findings, sex, age, and reconstruction kernel) through adaptive layer normalization. The model leads strong volumetric baselines on tri-planar Frechet distance (FID 32.3 vs. 74.6 for MAISI) while exposing direct control over clinical attributes. To strengthen that control we add an online reinforcement-learning post-training stage (group-relative policy optimization) that rewards how reliably a classifier recovers the requested findings from each generated volume. Judged by a separate, independent classifier, post-training removes 47% of the shortfall relative to real-scan reliability. We release the model and a ~200k synthetic chest-CT dataset with conditioning metadata spanning a wide variety of clinical findings.

High definition map generation is essential for autonomous driving, yet remains a labor-intensive process at scale. We present MapDreamer, a generative diffusion model that synthesizes lane-level vector maps with explicit topology directly from a single aerial image. MapDreamer learns a compact latent representation of lane centerlines and their topological relations using a variational autoencoder and predicts graphs with a transformer-based latent diffusion model. To align generated maps with the observed scene, we condition each denoising step on dense aerial features injected through cross-attention. To handle the varying number of lanes across scenes, we propose a lane cardinality module paired with background ghost lane latents, a learned buffer that prevents slot collapse during diffusion. Furthermore, we introduce a sliding-window global graph aggregation strategy that stitches local tiles into city-scale maps while preserving connectivity through encoded lane boundaries. Experiments on UrbanLaneGraph derived from Argoverse 2 show improved geometric and topological fidelity over non-generative baselines.

We present SynLaD, a latent diffusion framework for small-molecule generation that unifies ligand-based drug design objectives (what to make) with synthetic accessibility (how to make it). Current models typically optimize one objective at the expense of the other, creating a bottleneck for discovering high-scoring and synthesizable molecules. SynLaD combines reaction-constrained generation with pharmacophore-conditioned 3D design by learning a latent space that decodes to both 3D structures and synthesis pathways. An encoder maps molecules to a latent representation used by two decoder heads: (i) a geometric head that reconstructs atom types and coordinates and (ii) an autoregressive synthesis head that outputs synthetic routes in a serialized, reaction-based notation. A diffusion transformer generates novel latents in the learned space, conditioned on pharmacophore profiles. Across analogue generation tasks for bioactive ligands, SynLaD outperforms existing baselines in synthesizable and diverse hit generation, demonstrating that a single model can produce shape-aligned molecules with feasible synthesis plans.

World models can enable Model Predictive Control (MPC), but this requires dynamics prediction that is both fast enough for online use and expressive enough to represent uncertain futures. Diffusion models offer a natural mechanism for modeling uncertain dynamics, yet their iterative inference procedure makes them difficult to use for low-latency latent planning. We bridge this gap with Value Diffusion World Models (Valdi), combining end-to-end online training for MPC with a latent diffusion dynamics model. In preliminary experiments on the CarRacing environment, we show that Valdi, using a single diffusion step at both training and inference, matches a deterministic MLP baseline. Our experiments expose a trade-off between predictive multimodality and control performance in this setup. Code is available at https://github.com/Kit115/ValueDiffusionWorldModels.

Generative image steganography synthesizes stego images directly from secret information to achieve inherent security advantages. Latent Diffusion Models (LDMs) have recently emerged as a fundamental image steganography framework that modulates secret latent representations with text prompts. Limited by the inflexibility of text prompts, these methods still struggle to generate high-quality stego images and accurately recover secret images. In this work, we propose a prompt-free diffusion image steganography framework that integrates style semantic priors to control more robust and reliable stego image generation. Specifically, a Cascaded Affine Coupling Module (CACM) establishes a bijective, deterministic mapping between a secret image and its latent representation. Then, style semantics are integrated into the diffusion process to control latent representation and ensure visual imperceptibility in the generated stego images. To mitigate trajectory deviations stemming from the unconditioned reverse process, a predictor-corrector mechanism is introduced to iteratively refine the generation trajectory via feedback from the current and predicted next states. Extensive experimental results show that the proposed method achieves competitive performance compared to state-of-the-art methods in terms of security, secret image reconstruction accuracy and controllability.

Image-to-image (I2I) translation has achieved strong results in tasks like human relighting and driving scene translation using latent diffusion models (LDMs). However, compact LDMs often struggle to preserve fine-grained structures because the encoder compresses high-resolution inputs into a spatially downsampled latent space. To address this issue, we propose a simple saliency-guided warp-unwarp framework that reallocates spatial representation toward salient regions before encoding, enabling better preservation of structural details without increasing latent resolution. The warped image is processed by the original diffusion model and then mapped back via an inverse warp. In addition, we propose a simple and efficient outpainting-based synthetic data generation pipeline to produce high-quality paired data for image relighting. Our method is model-agnostic, requires no architectural modification, and introduces negligible computational overhead. Experiments on human relighting, driving scene relighting, and translation demonstrate improved structural preservation, lighting faithfulness, and image quality, with our framework extending naturally to video via frame-by-frame application with good temporal stability. Project Webpage: https://shenzheng2000.github.io/WarpI2I.github.io

Recent studies have shown that semantic watermarks, which embed information into the initial noise of latent diffusion models (LDMs), are vulnerable to black-box forgery attacks. However, existing methods primarily rely on empirical evidence and lack a rigorous theoretical understanding of the conditions under which such attacks succeed or fail. To bridge this gap, we rethink the nature of such attacks through the lens of rate-distortion in the latent space. Our analysis identifies an irreducible distortion floor due to structural mismatches between proxy and target models, which fundamentally limits the fidelity of forged watermarks. We further characterize this distortion as structured geometric deviations on the latent manifold, in the form of global drift and local deformation rather than stochastic noise. Leveraging these insights, we propose a scheme-agnostic detection method that distinguishes forged samples before watermark verification. Extensive experiments demonstrate the effectiveness of our method across diverse black-box scenarios, while preserving robustness to common distortions.

Developing robust artificial intelligence models for 4D (3D + time) medical imaging is constrained by limited annotated data, inter-device domain shifts, and privacy restrictions. To address this, we propose a 4D controllable generative framework for anatomically consistent data augmentation. A semi-supervised variational autoencoder learns a compact latent representation of anatomical volumes while jointly predicting aligned segmentation masks in a unified framework. Anatomical structure is then disentangled from temporal dynamics through a cascaded latent diffusion model (LDM). A static LDM generates subject-specific anatomy conditioned on clinical priors (diagnosis and volumes measures) and a subsequent motion LDM estimates residual latent motions, ensuring strict temporal coherence across the 4D sequence. The proposed approach was evaluated on cine cardiac MRI as a representative 4D imaging application. Experiments across multiple datasets demonstrate high controllability of static anatomy (Pearson r > 0.8) and strong temporal coherence (FVD = 288.08). In cross-vendor generalization experiments, augmenting training sets with synthetic 4D sequences significantly improves downstream segmentation performance. Using nnU-Net, the proposed augmentation strategy improves the average Dice score by 1.4% and reduces the Hausdorff Distance by 3.0mm compared to training on real data alone, for the left ventricle, Dice improves by 2.8% with a 5.4mm reduction in boundary error. Overall, this framework provides a scalable and controllable solution for 4D medical image synthesis, supporting the development of more robust models with limited annotations and cross-vendor variability. Code available on https://github.com/cyiheng/4DCardiacMRISynthesis.

Latent diffusion models achieve strong generative performance by operating in a compressed latent space produced by a variational autoencoder (VAE). However, it remains unclear whether all latent channels contribute equally to the diffusion process, or whether significant redundancy exists. We introduce PeLAP-A (Adaptive Latent Pruning for Diffusion), a lightweight framework that augments a standard latent diffusion pipeline with a learnable channel-wise importance predictor. A two-layer MLP operating on globally pooled latent features produces a soft mask that suppresses unimportant latent channels before they enter the denoising UNet. The entire system is trained jointly on CIFAR-10 under a combined diffusion, reconstruction, and sparsity loss. Experiments reveal a striking result: under aggressive sparsity regularization (lambda = 0.01), the importance predictor drives all latent channels to near-zero yet the denoising UNet achieves lower diffusion loss (0.0236 vs. 0.0240) and lower VAE reconstruction MSE (22.59 vs. 24.67) compared to the unpruned baseline. We term this the sparsity collapse phenomenon and provide an analysis of why it occurs and what it reveals about the information requirements of latent diffusion models. These findings constitute an exploratory study of sparsity dynamics in latent diffusion training, and demonstrate that denoising UNets can remain remarkably robust to latent channel suppression even under aggressive regularization. Code is available at: https://github.com/kissasium/PeLAP-A.git.

Training Latent Diffusion Models (LDMs) within Federated Learning (FL) has attracted increasing attention due to its ability to combine the powerful generative capacity of LDMs with the privacy-preserving properties of FL. However, FL requires sharing the global model with multiple participants, which risks unauthorized model distribution or resale by malicious clients. While an intuitive approach is to adopt existing VAE-based watermarking techniques for LDMs in FL, this strategy falls short in addressing such threats due to two fundamental challenges: (1) Existing methods support ownership verification but lack the ability to trace model leakage to a specific malicious client; (2) VAE-based watermarks are vulnerable, as they can be removed simply by replacing the decoder with a clean counterpart. In this paper, we propose FedOT, the first framework for ownership verification and leakage tracing in federated LDMs. Specifically, to address the first challenge, we design a chunked watermark, where the first part is for ownership verification, and the second part is used for client identification. Furthermore, to overcome the second challenge and secure the model against VAE replacement attack, we introduce Latent Vector Transformation (LVT), which strengthens the connection between the VAE and U-Net latent spaces by modifying the original latent distribution of the VAE. Consequently, any attempt to replace the VAE for watermark removal leads to significant image quality degradation, making the LDM model unusable. Extensive experiments demonstrate that FedOT achieves superior performance in both ownership verification and traceability. Project page: https://spyzixuan.github.io/FedOT/.

Most diffusion and flow-matching generators define the prior, probability path, and prediction target in the same representation space. Latent diffusion improves efficiency by moving this path into an autoencoder latent space, but the final sample is still produced by a separately trained decoder. This separation creates a mismatch: the generator is optimized for latent-space prediction, while final quality depends on how the decoder handles generated latents that may differ from clean encoder outputs. We introduce CrossFlow, a cross-space flow formulation that maps noisy latent inputs directly to pixel-space images. The key technical step is a velocity-free one-step objective: the latent trajectory defines the training path, but the supervised prediction is an image rather than a latent displacement. This lets one model act both as a one-step latent-to-pixel generator and as a decoder replacement for latent diffusion pipelines. On class-conditional ImageNet-1k at $256\times256$, CrossFlow-XL achieves 1.62 FID with one function evaluation. Ablations show that the latent encoder and pixel-space perceptual and adversarial losses are important for fidelity. These results indicate that cross-space flow objectives can combine the efficiency of latent representations with direct pixel-space supervision, without requiring a separate decoder at inference.

Latent diffusion models (LDMs) enable efficient image-to-image translation but discard fine spatial details during compression, degrading downstream perception tasks. We identify two bottlenecks: the autoencoder, which loses spatial information, and the conditioning pathway, which further degrades the source signal through naive downsampling. We propose two lightweight, backbone-agnostic fixes: a Source-Conditioned Autoencoder (SCAE) that injects high-resolution source features into the decoder via skip connections, and a Learnable Guidance Encoder (LGE) that replaces naive downsampling with a learned conditioning signal. Evaluated on RGB-to-SWIR translation for driving scenes with two denoiser backbones (U-Net and DiT), our approach improves detection mAP by up to 2x over the latent diffusion baseline, with up to 3.4x gains on small objects (COCO-small, <32^2 px^2), while achieving state-of-the-art FID. We further show that FID and detection performance are poorly correlated, motivating multi-axis evaluation. Results generalise zero-shot to the public RASMD benchmark. We will publicly release test data with annotations, all checkpoints, and training code.

Valuable critique of generative image models within visual culture and the humanities has emphasized the role of datasets in shaping the images they produce. Yet, close studies of the ideological positions embedded into the mechanism of the models have been neglected, leaving them imagined as "black boxes." In a bid to expand, rather than replace, dataset critique, this paper examines the mechanisms of the latent diffusion model in terms of the problems they were brought in to solve on behalf of computer vision engineers, and the decisions each component was tasked with automating. I interpret that ensemble through the histories of its parts and the theory of vision the system inscribes into every generated image. Drawing on Impett and Offert's notion of neural exchange value, I offer this analysis to argue that the model operates as a neural economy: a contained symbolic system that abstracts social communication into commensurable vectors as it transfers the social sphere into parcels for sale. Tracing the training and generation pipelines component by component reveals what each operation displaces, and how it further entrenches the logics of platform and attention economies over social communication. The paper warns that any critique fixated exclusively on copyright and commodity defenses risks reaffirming the very fetishism the model produces, and argues instead for centering social exchange.

We introduce MUNI, an end-to-end multimodal latent diffusion framework for any-to-any generation that unifies subset-conditioned cross-modal generation and unconditional joint sampling through a shared stochastic latent. Existing multimodal generative models are largely LLM-based, which limits leveraging modality-specific generators and requires text-paired data for training. Recent diffusion- and flow-based any-to-any extensions take a different direction but still rely on text-aligned embeddings, fully-paired training, or matched-dimensionality deterministic mappings. MUNI rests on two complementary contributions, one architectural and one in the training objective. First, we extend latent diffusion to multimodal any-to-any generation end-to-end: instead of the standard two-stage recipe that precomputes a frozen latent space and then fits a prior over it, MUNI jointly trains modality-specific encoders, expressive decoders, and a single shared flow-based prior under one objective. Second, we identify that the standard aggregation rules of multimodal variational inference are insufficient once coupled with a learned prior and expressive decoders. A suitable shared latent must simultaneously satisfy coherence across generated modalities, predictive sufficiency of subset latents, and minimality of the latent content. We propose a routed training objective whose structural choices align the latent with these criteria and admit a minimal-sufficiency characterization in the realizable setting. Experiments on PolyMNIST-Quadrant-Labels and a large-scale image-text-audio benchmark show MUNI matching or exceeding the strongest baselines on conditional generation while opening its largest margins on unconditional coherence. Project page: https://muni-proj.github.io/.

Simulation is central to validating autonomous driving systems, yet current pipelines are limited by insufficient scenario diversity due to costly High Definition (HD) map creation. Scaling HD maps requires expensive data collection and manual processing. Moreover, existing generative models lack the fine-grained control necessary to target specific road topologies during generation. This paper presents a data-driven pipeline for controllable HD map generation using latent diffusion and ControlNet for spatial conditioning. To our knowledge, we are the first to inject spatial guidance signals into a diffusion model for HD map synthesis. Furthermore, our model supports adjustable conditioning strength through classifier-free guidance and city-level style transfer via city label conditioning. To complement existing metrics, we introduce two novel metrics to evaluate adherence to the control signal and similarity to ground-truth maps. Experiments demonstrate that our model generates realistic HD maps that faithfully follow input road topologies while accurately preserving city-specific details.

Hematoma expansion (HE) after spontaneous intracerebral hemorrhage (ICH) is a major determinant of acute triage and treatment decisions in neurosurgical care. However, most existing methods provide either a binary expansion risk or a single follow-up volume, limiting uncertainty-aware decisions. We introduce HemExp, a clinically-guided latent diffusion model that generates patient-specific follow-up non-contrast CT images, along with segmentations of intraparenchymal and intraventricular hemorrhage. Generation is conditioned on baseline imaging, clinical variables, and an explicit expansion indicator, enabling controllable simulation of realistic clinical scenarios. HemExp uses a hemorrhage-aware multi-head variational autoencoder and models progression as the difference between baseline and follow-up latent representations with a conditional diffusion model. The model is trained on paired scans from 450 patients across multiple centers and evaluated on 107 patients from a held-out institution. HemExp produces spatial HE probability maps by generating multiple synthetic follow-up images per patient to estimate distributions of plausible follow-up hematoma volumes. Perturbing clinical inputs such as symptom-onset-to-imaging time or anticoagulant status shifts the predicted follow-up volume distribution. HemExp extends binary predictors and demonstrates robust estimation of clinically relevant outcomes in the imaging space, such as hematoma volume, intraventricular involvement, and mass effects. Overall, our results support controllable latent diffusion as a promising direction for uncertainty-aware modeling of early ICH progression.

While Latent Diffusion Models (LDMs) have revolutionized visual synthesis, they are increasingly exploited for unauthorized mimicry of individuals. Existing defenses inject deceptive perturbations to steer the generated images toward irrelevant targets. However, this approach hinges on an ungrounded assumption: subtle perturbations can maintain their deceptive efficacy throughout an LDM's extensive generation process. In reality, the model's innate restoration mechanism will remove such perturbations and cause individual identities to re-emerge in the images generated. We propose VOID, a defense framework that overcomes this conundrum by manipulating an LDM's intrinsic stochasticity. VOID perturbs the diffusion pipeline in two novel ways: 1) amplifying the latent encoding errors to shatter an image's semantic structure, and 2) counteracting the target guidance signals to suppress the model's restoration capabilities. This results in a semantic corruption that thwarts any unauthorized mimicry. Notably, the security gain does not come at the price of visual utility, as VOID simultaneously manages to confine perturbations to human-imperceptible regions of protected images. Our comprehensive evaluation of 24 state-of-the-art defenses against 10 mimicry attacks on 5 datasets demonstrates VOID's unprecedented protection power: it increases the average Frechet Inception Distance (FID) from 113 to 365, a 223% improvement over the strongest defense to date.

Data assimilation (DA) in subsurface flow entails calibrating model parameters to match observed data, typically at wells, while preserving geological realism. Latent diffusion models (LDMs) provide efficient mappings from high-dimensional geological model space to a low-dimensional latent variable, reducing the dimensionality of the inverse problem while maintaining plausibility in posterior geomodels. However, the high nonlinearity in the LDM mapping may degrade the performance of Kalman-gain-based ensemble updates. We present a systematic comparison of DA algorithms applied to large-scale 3D channelized geomodels with hierarchical geological uncertainty. We compare model-space and latent-space DA using the ensemble smoother with multiple data assimilation (ESMDA), and demonstrate a key trade-off: model-space updates achieve significant uncertainty reduction but produce geologically unrealistic posterior models, while latent-space updates preserve realism but exhibit limited uncertainty reduction. Motivated by this, we explore rigorous Markov chain Monte Carlo (MCMC) and Sequential Monte Carlo (SMC) algorithms in the 3D-LDM latent space. To accommodate their high computational demands, we develop a fast surrogate flow model that approximates well-rate responses. MCMC and SMC are evaluated against ESMDA across three synthetic test cases, with DA performed in the LDM latent space. All models maintain geological realism due to the LDM parameterization. MCMC and SMC are consistent with one another and achieve lower data mismatch and more uncertainty reduction than latent-space ESMDA. Our overall results demonstrate that ensemble Kalman methods may provide overestimated posterior uncertainty with highly nonlinear parameterizations, while rigorous Monte Carlo sampling, enabled by fast surrogate models, can provide a more reliable alternative.

3D semantic scene generation is crucial for autonomous driving applications, yet most methods rely on complex 3D-specific architectures such as triplane encoders and adapted diffusion networks, limiting both their simplicity and their editing capabilities. We propose EditSSC, an editing-ready method for 3D semantic scene generation using 2D Bird's Eye View (BEV) representations and off-the-shelf latent diffusion network. Our approach reshapes 3D semantic occupancy grids into multi-channel BEV images and leverages the quantized autoencoder and UNet from Stable Diffusion with minimal modifications. We perform diffusion on the latents after quantization, which enables training-free editing capabilities. By exploiting class-to-code correspondences in the codebook, our method supports sketch-guided generation, inpainting, and outpainting without any retraining. On SemanticKITTI, EditSSC outperforms existing 3D-specific baselines on unconditional generation, demonstrating that well-established 2D architectures can be effectively repurposed for 3D scene generation and editing.

Gaussian-corrupted sentence embeddings have no direct linguistic interpretation, yet continuous diffusion language models can generate fluent text from them. We study this puzzle through Embedded Language Flows (ELF) and identify a decoder-basin mechanism: our evidence suggests that denoising becomes reliable when trajectories reach regions where the native decoder can read stable tokens. We introduce a diagnostic protocol for denoisability, semantic recoverability, order sensitivity, decoder compatibility, and trajectory reliability. It exposes failures hidden by scalar metrics: low mean-squared error can discard linguistic content, low perplexity can reflect low-entropy collapse, and clean latent reconstruction can coexist with a narrow decoder basin. A decoder-margin bound explains why token recovery depends on margin and local decoder sensitivity, not latent error alone. Auditing public ELF checkpoints reveals an interface phase diagram: early predictions are weakly readable, mid-trajectory disagreement marks a competition region, and late predictions enter a high-margin decoder basin. Once inside, token realization is surprisingly simple on generated ELF states: frozen T5 (Text-to-Text Transfer Transformer) token-embedding lookup recovers $93$--$96\%$ of native decoder decisions, and a single linear readout reaches $97.9\%$ agreement at 32k samples, leaving an $\approx1.1$--$1.2$ perplexity gap in a structured residual tail. Under conservative held-out gates, a margin rule exits roughly $17$--$28\%$ earlier in denoising steps under an explicit diagnostic monitor. Boundary checks on LangFlow, BitstreamDiffusion, and the Continuous Latent Diffusion Language Model (Cola-DLM) show that the same interface questions remain meaningful when the state object and decoder change. Continuous and latent diffusion language models should therefore be evaluated as representation-decoder systems.

Diffusion-based visuomotor policies operating directly in raw action spaces conflate scene comprehension with trajectory generation within a single denoising process. The resulting velocity field must simultaneously encode scene information and generate precise trajectories, increasing learning complexity and limiting performance on tasks demanding precise temporal coordination across multiple arms. To simplify this joint learning problem, we introduce Latent Diffusion Policy (LDP), a two-stage framework performing flow matching in a deliberately shaped latent space. By absorbing scene understanding into an observation-conditioned CVAE encoder, LDP concentrates the conditional distribution of each observation. Consequently, the flow model avoids implicitly resolving scene-dependent structures; instead, it generates within a pre-concentrated distribution featuring a smoother velocity field, simplifying learning from limited demonstrations. Furthermore, to capture temporal dependencies among latent tokens, LDP trains with per-token diffusion forcing and employs staircase inference sampling to resolve the resulting distributional mismatch. We also propose reconstruction FID (rFID) as a lightweight proxy predicting downstream task success solely from latent space statistics. On coordination-intensive tasks from RoboTwin 2.0, LDP outperforms DP3 by a substantial margin and transfers effectively to real-world bimanual deployments.

With the growing concerns over copyright infringement in diffusion-based customization, adversarial attacks have emerged as a prominent defense strategy to prevent malicious content forgery in personalized image generation. However, current defenses typically introduce persistent perturbations in the latent space of Latent Diffusion Models (LDMs), which remain susceptible to adaptive bypasses by adversaries. In this paper, we introduce Two-Stage Latent Feature Optimization (TS-LFO), an efficient and effective copyright-stealing attack against protected diffusion-based customization. We begin by observing that existing defenses primarily disrupt the mapping between input images and their latent representations, thereby degrading the model's ability to produce personalized outputs. To counteract this, TS-LFO restores the broken mapping through a two-stage optimization process. In the Latent Denoising Stage, we enhance semantic consistency between latent codes and input images by jointly minimizing a Latent-Image Alignment Loss and a Latent Diffusion Loss with timestep-dependent weights, effectively suppressing the high-frequency noise introduced by defenses. In the Latent Reconstruction Stage, we recover low-frequency semantic information using pixel-level constraints to refine the latent features. Extensive experiments show that TS-LFO consistently bypasses state-of-the-art (SOTA) copyright defenses and outperforms SOTA copyright attacks such as DiffPure, GrIDPure and IMPRESS across diverse settings.

This paper introduces ARAPDiffusion, a latent diffusion model to learn the underlying continuous shape space of a deformation shape collection. The key innovation is in injecting the as-rigid-as-possible (ARAP) deformation model as regularization losses into latent diffusion (LD), releasing the requirement of having abundant 3D training data for learning generative models. In contrast to the standard LD, we show how the ARAP model can be used to improve both the encoder/decoder and the LD model. The training procedure alternates between using the synthetic distribution defined by the LD model to develop a regularization loss that enhances the shape encoder/decoder and using the shape decoder to develop a regularization loss to improve the LD model. We also show the benefit of the LD paradigm in combining a representation-free LD process and an implicit shape decoder that is applicable to unorganized point clouds. The experimental results of unconditional and conditional shape generation demonstrate the advantages of ARAPDiffusion over baseline approaches.

Text-to-Image (TTI) systems are now everyday infrastructure for journalism, education, advertising, and public communication, and the demographic and cultural stereotypes they inherit from training data (rendering women, people of colour, older adults, and non-Western cultures as under-represented or caricatured) become a population-level harm at deployment scale. Existing mitigations either require costly retraining, infeasible for the closed-source backbones that dominate consumer products, or rely on fixed demographic templates that ignore cultural context. We present KG-FairDiff, a model-agnostic, inference-time framework that formalises fairness-aware prompt refinement as a constrained optimisation problem and operationalises it as a closed-loop pipeline: a knowledge graph of ~1,200 culture- and bias-related triples retrieves structured context, an LLM rewriter proposes refinements, and a validator accepts only prompts that reduce a divergence-based fairness loss while preserving semantic fidelity to the user's original intent. We prove a finite-termination bound for the refinement loop, contribute a mathematically consistent evaluation suite linking Bias-P/Bias-W to divergence from target distributions and ENS to KL divergence, and audit eight widely-deployed backbone generators. KG-FairDiff substantially reduces gender, race, age, and intersectional disparities while preserving prompt semantics, offering a practical, deployment-ready route to more equitable generative AI.

Fast and accurate prediction of crystal properties is a central challenge in new materials design. Graph neural networks and Transformer-based models have emerged as powerful tools for this task due to their ability to encode the local structural environment of atoms within a crystal. However, these models are data-hungry, and in practice, labeled data for crystal properties are scarce. Pretraining-finetuning strategies, particularly those based on diffusion models, have shown promise in addressing these limitations. In this work, we introduce a novel latent diffusion based pretraining framework, CrysLDNet, designed to mitigate data scarcity. Our approach integrates a Variational Autoencoder (VAE) with a diffusion model during the pretraining stage. The VAE encoder maps 3D crystal structures into a smooth latent space within which the diffusion process is applied. This latent diffusion pretraining enables the graph encoder to effectively capture structural and chemical semantics from large-scale unlabeled data, which can then be finetuned for specific property prediction tasks. Comprehensive experiments on popular DFT datasets for property prediction reveal that CrysLDNet significantly outperforms both training-from-scratch and pretrained baselines, with improvements of 4.26% and 4.90% on the JARVIS and MP datasets, respectively. Additionally, the learned representations remain robust in sparse-data conditions and are expressive enough to correct DFT errors when finetuned with limited experimental data. Code is available at: https://github.com/shrimonmuke0202/CrysLDNet.git.

Multimodal MRI provides complementary information for neuroimaging analysis, where different imaging modalities capture distinct anatomical, tissue, and pathological features that support the development and evaluation of downstream AI applications. Although large-scale structural MRI resources are increasingly available, their modality coverage is often uneven across public and pooled neuroimaging datasets. This uneven modality coverage is further complicated by heterogeneity across sites, scanners, and acquisition protocols, as well as demographic and clinical variables that are often sparse, inconsistently recorded, or unavailable across studies. Synthetic MRI generation can help address this imbalance by synthesizing target-modality volumes for dataset augmentation and controlled synthetic cohort creation. However, many existing MRI synthesis approaches are trained on narrow modality sets or relatively homogeneous cohorts, limiting their applicability to large pooled neuroimaging resources where modality availability, acquisition protocols, and metadata coverage vary substantially across datasets. Diffusion models have become an attractive approach for MRI synthesis because of their strong sample fidelity and diversity, but sampling directly in 3D voxel space is computationally expensive and slow at inference. Latent diffusion improves practicality by synthesizing MRI in a learned, 3D latent space, although generation quality depends on the autoencoder's reconstruction fidelity and the resulting latent distribution. Our approach combines a Wavelet-Fusion variational autoencoder (WF-VAE) latent compressor with a conditional 3D U-Net diffusion model trained in the learned latent space using explicit modality and metadata conditioning. Our proposed Wavelet-Fusion Diffusion Model (WFDM) achieved the strongest distributional alignment among the evaluated synthetic MRI generators.

We present UNISON, a latent diffusion framework that unifies speech generation, sound generation, and audio editing within a single model. A single model handles text-to-audio, text-to-speech, zero-shot speaker cloning, mixed speech-and-sound generation, scene-level audio editing, speech-in-scene editing, and timed temporal composition, all of which share a single set of weights. Our architecture features two core designs: (1) Layer-wise deep LLM fusion, which injects hidden states from uniformly sampled layers of a frozen MLLM into corresponding MM-DiT blocks via learned projections, providing depth-matched semantic conditioning that improves instruction following over single-layer baselines; and (2) a unified multi-task architecture where task identity is encoded solely by a channel-wise mask and source audio is provided through VAE-encoded channel concatenation. Training is stabilized by an online GPU-side multi-task data synthesis pipeline with task-homogeneous batching and a two-stage curriculum. With 621M--732M trainable parameters, UNISON achieves results competitive with or exceeding task-specialist models across evaluated domains, while being roughly $4\times$ smaller than comparable unified systems.

Cross-modal 2D-3D gait recognition is impeded by inherent domain discrepancies between 2D silhouette and 3D LiDAR range-view representations. While prior methods align only final embeddings, we propose DiffCrossGait, which reformulates cross-modal matching as trajectory-level alignment in an identity-relevant latent diffusion space, rather than assuming full equivalence between 2D and 3D observations. By driving both modalities with shared Gaussian noise within a latent space, we enable continuous alignment throughout the generative evolution. We introduce a Tri-Phase Alignment Strategy that exploits varying noise intensities to enforce identity anchoring, dynamics consistency, and cross-modal structural recoverability, thereby constraining both modalities to share denoising dynamics and bottleneck structure, which promotes modality-invariant gait features. Crucially, our framework decouples generative alignment from the discriminative backbone; the diffusion mechanism serves exclusively as a training objective, ensuring high inference efficiency by eliminating the computational overhead of iterative denoising. Extensive experiments on the SUSTech1K and FreeGait benchmarks demonstrate that DiffCrossGait achieves state-of-the-art performance.

Diffusion models have emerged as powerful generative approaches for missing-data imputation, yet most existing methods operate directly in data space and degrade when training data are heavily incomplete. We investigate whether shifting diffusion to a learned latent representation improves robustness under missing-completely-at-random (MCAR) corruption. To this end, we propose a two-stage framework: a robust VAE-based imputer first learns compact semantic features from incomplete observations, and a diffusion model is then trained in the resulting latent space. Across training missing rates, we perform a controlled comparison against pixel-space diffusion models under the same incomplete-data setting. The latent diffusion model maintains high sample quality and remains stable up to 50% missingness, while pixel-space diffusion degrades progressively as missingness increases. For downstream imputation, latent diffusion also achieves consistently better performance than pixel-space diffusion. These findings indicate that latent-space modeling mitigates artifact amplification from zero-imputed inputs and provides a more robust generative prior for incomplete-data learning. Overall, our results support latent diffusion as a strong and practically useful alternative to pixel-space diffusion for missing-data problems.

Small-molecule drug discovery requires simultaneous optimization of numerous properties of candidate molecules. These properties can be investigated through the analysis of high-dimensional biological signatures, such as cell morphology and transcriptomic perturbations, which provide a rich perspective on the underlying biological mechanisms. However, existing generative methods, which use those signatures for optimization, fail to meet two key requirements: providing precise guidance toward desired phenotypic signatures while maintaining structural proximity to a known hit. We introduce PhAME (Phenotype-Aware Molecular Editing), a latent diffusion framework that overcomes this challenge by recasting molecular optimization as editing in the latent space of a pretrained graph-based VAE. Our central contribution is a compositional classifier-free guidance scheme with two independent scales, one for the phenotype-conditioning and one for similarity to the seed structure, allowing practitioners to control the tradeoff between these two objectives. Empirical evaluations across diverse benchmarks, including docking score optimization and multimodal phenotypic generation, demonstrate that PhAME achieves state-of-the-art results while maintaining high chemical validity and novelty.

Flow matching with clean-data prediction has shown that regressing the clean point can exploit low-dimensional structure more effectively than predicting an ambient noised quantity. We ask whether this principle remains useful after images are mapped into a learned latent space, where compression has already removed much of the raw pixel variability. We introduce JLT, a 130M latent diffusion Transformer over frozen FLUX.2 VAE codes, and compare clean-latent prediction with a matched velocity-prediction DiT under the same representation, backbone, and training settings. Although the three variables x, epsilon, and v are linearly convertible for a fixed corruption time, a local Gaussian analysis shows that velocity regression inherits an isotropic target-covariance floor and amplifies low-variance latent directions, while clean prediction damps them. On ImageNet 256 x 256, JLT-B/1 obtains FID-50K 2.50 with classifier-free guidance, with a large matched-target gap over velocity prediction. These results suggest that prediction targets in latent diffusion are representation-dependent geometric choices, rather than interchangeable algebraic parameterizations.

Energetic-materials performance gains translate directly into reduced propellant mass, smaller warheads, and more efficient civilian gas-generators, yet no new HMX-class compound has been disclosed in fifteen years. Designing one is a sparse-label problem: of ~66 k labelled CHNO molecules only ~3 k carry experimental or DFT-quality measurements, and naive generative models trained on the full mixture either memorise the high-performance tail or extrapolate without calibration. We introduce Domain-Gated Latent Diffusion (DGLD): a label-quality gate at training time, multi-task score-model guidance at sample time, and a four-stage chemistry-validation funnel ending in first-principles DFT audit. The result is 12 DFT-confirmed novel leads. The headline compound, 3,4,5-trinitro-1,2-isoxazole (L1), reaches \r{ho}"cal" =2.09 g/cm3 and D"K-J,cal" =8.25 km/s and is structurally dissimilar from all 65 980 training molecules (nearest-neighbour Tanimoto 0.27). A co-headline lead, E1 (4-nitro-1,2,3,5-oxatriazole), exceeds L1 on calibrated detonation velocity (D_"K-J,cal" =9.00 km/s) from a chemotype family disjoint from L1's. DGLD is the only method to land in the productive quadrant (simultaneously novel and on-target) at DFT level. SMILES-LSTM memorises 18.3% of its outputs exactly; SELFIES-GA's best novel candidate loses 3.5 km/s under DFT audit; REINVENT 4 generates novel high-N heterocycles but peaks at D=9.02 km/s. Code, checkpoints, and 918 mined hard negatives are released on Zenodo (DOI 10.5281/zenodo.19821953); the next compound to enter the HMX-class band can be discovered, validated, and recommended for synthesis at the cost of a few GPU-days.

Most practical high-resolution text-to-image systems, including latent diffusion and autoregressive models, perform generation in a compact latent space, and a decoder maps the generated latents back to pixels. Yet the latent-to-pixel decoder is reconstruction-oriented, optimized to invert the encoder rather than synthesize more details, and becomes increasingly costly at megapixel scale. This drawback calls for a more expressive and efficient decoding paradigm. Motivated by recent progress in scalable pixel-space diffusion, we introduce PiD, a Pixel diffusion Decoder that reformulates latent decoding as conditional pixel diffusion, unifying decoding and upsampling into one generative module. By denoising directly in high-resolution pixel space, PiD synthesizes $4\times$ and even $8\times$ upscaled images with low latency. For latent conditioning, a lightweight sigma-aware adapter injects noise-corrupted latents into the pixel diffusion backbone, enabling PiD to decode partially denoised latents and terminate the latent diffusion process early. To further improve efficiency, we distill the model using DMD2, reducing inference to just 4 steps. PiD applies to both conventional VAE latents and semantic latents (e.g., SigLIP, DINOv2) used in recent RAE-based models. PiD decodes latents of $512 \times 512$ images into $2048 \times 2048$ pixels in under 1 second with 13 GB peak memory on a consumer RTX 5090, and as fast as 210 ms on a GB200 GPU, about $6\times$ faster than cascaded diffusion-based super-resolution pipelines with better visual fidelity.

Representation Autoencoders (RAEs) leverage frozen vision foundation models (VFMs) as tokenizer encoders, providing robust high-level representations that facilitate fast convergence and high-quality generation in latent diffusion models. However, freezing the VFM inherently constrains its spatial reconstruction capacity, limiting fine-grained generation and image editing; in contrast, incorporating reconstruction-oriented signals via fine-tuning disrupts the pretrained semantic space and degrades generative fidelity. To address this trade-off, we propose DecQ, a simple yet effective framework for RAEs. Specifically, DecQ introduces lightweight detail-condensing queries that extract fine-grained information from intermediate VFM features through condenser modules. These queries are incorporated into the decoder to support reconstruction and are jointly generated with patch tokens during generative modeling. By aggregating information from both shallow and deep layers, DecQ effectively mitigates the reconstruction--generation trade-off, improving both reconstruction quality and generative performance. Our experiments demonstrate that: (1) with only 8 additional queries and 3.9% extra computation, DecQ improves reconstruction over the frozen DINOv2-based RAE, increasing PSNR from 19.13 dB to 22.76 dB; and (2) for generative modeling, DecQ achieves 3.3$\times$ faster convergence than RAE, attaining an FID of 1.41 without guidance and 1.05 with guidance.

Foundation video models produce visually impressive results, but their use in embodied AI remains limited because they are primarily trained on natural language rather than low-level control signals. This limitation is especially pronounced for aerial flight, where motion occurs in unconstrained 6-DoF space and small errors in ego-motion can produce large trajectory drift. Generating aerial videos that follow fine-grained inertial actions can support scalable training and evaluation of aerial agents by providing a controllable proxy for real-world or expensive simulation data. To address this problem, we propose \textbf{Aero-World}, a method for converting a pretrained image-to-video diffusion model into a controllable aerial video generator. Aero-World injects sequences of translational acceleration and angular velocity into a pretrained latent diffusion transformer through an action-token stream. A frozen latent-space Physics Probe, trained independently on real video--IMU pairs, provides differentiable inertial-consistency supervision during LoRA finetuning while avoiding computationally expensive video decoding. We further propose \textbf{AeroBench}, a benchmark for evaluating whether generated drone videos adhere to low-level action signals. AeroBench uses Action Alignment Score (AAS) to measure agreement with commanded inertial actions and Physical Consistency Rate (PCR) to measure temporal motion stability. On AeroBench, Aero-World improves mean AAS from 57.7 to 63.6 over action-only finetuning and gives a stronger quality-control trade-off than AirScape, with lower FVD (596.5 vs. 1058.6), higher SSIM (0.595 vs. 0.505), and higher Flow-IMU correlation (0.44 vs. 0.20). These results suggest that frozen Physics Probe supervision is a practical mechanism for adapting pretrained video generators toward more action-aligned aerial motion.

Electrocardiogram (ECG)-based models have achieved strong performance in diagnostic tasks, yet they remain limited in modeling how cardiac dynamics evolve under external interventions. In particular, existing approaches focus primarily on static prediction and lack mechanisms to capture ECG variations under different pharmacological conditions. In this work, we propose an ECG World Model for action-conditioned predictive simulation of cardiac electrophysiology. Moving beyond disjoint pipelines, our framework features a principled integration of physiological ordinary differential equation (ODE) priors into latent diffusion dynamics via energy regularization. This structural constraint enables the synthesis of physiologically plausible post-intervention ECG trajectories while effectively mitigating generative hallucinations. Building on this simulation process, we introduce an uncertainty-aware evaluation strategy that leverages the stochasticity of diffusion sampling to characterize both the expected clinical risk and its variability, allowing a more reliable comparative assessment of candidate interventions. We evaluate our method across diverse settings, including controlled drug-response scenarios and real-world clinical records. Beyond standard waveform metrics, experimental results demonstrate improved risk calibration and strong alignment with expert-informed treatment preferences. These results establish our approach as a robust foundation for safe and intervention-aware clinical decision support.

Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while neglecting a more fundamental bottleneck. We identify and formalize the learnability gap: large-scale pretrained autoencoders faithfully encode discriminative features for medical classification, as evidenced by near-lossless performance in reconstruction space, yet their latent representations are structured in ways that are difficult for classifiers to learn from. Across five autoencoder families and four medical benchmarks spanning chest radiography, dermatoscopy, computed tomography, and echocardiography, we show that this gap persists regardless of architecture, initialization strategy, or hyperparameter tuning, and that medical-domain fine-tuning of the autoencoder does not close it. To probe and partially narrow the gap, we develop noise-conditioned latent classifiers with FiLM layers and image-space distillation that offer 64x throughput and 120x memory gains over image-space models while serving as diagnostic tools for latent space quality. Our analysis provides a new framework for evaluating autoencoder latent spaces and identifies their structure, rather than their fidelity or domain specificity, as the primary obstacle to closing the performance gap between real and synthetic medical training data.