Medical Image Segmentation

Overview

Medical image segmentation assigns labels to pixels or voxels to outline structures such as tumors, organs, vessels, and surgical instruments, enabling quantitative analysis and clinical workflows. Common approaches include U-Net-style convolutional networks, transformers and state-space models, and promptable foundation models; work also uses anatomical and topological priors, text guidance, and generative models. To reduce reliance on dense expert labels, researchers study self-supervised pretraining, semi- and weakly supervised learning, synthetic data, and interactive annotation, while domain adaptation addresses differences across scanners, hospitals, and modalities. A central challenge is making models reliable beyond their training data: high overlap scores can conceal boundary, connectivity, small-lesion, or subgroup failures, so external validation, uncertainty estimates, and clinically relevant metrics remain important.

Latest papers

CardsList

788 papers62 papers in the last four weeks, down 29% on the four weeks before. 0.4% of all new papers.

  1. ResNet-34 with Lightweight Decoder for Accurate and Efficient Segmentation of Fetal Brain MRI

    May 31, 2026Ashiqur Rahman, Muhammad E. H. Chowdhury, Md. Abu Sayed +3Medical Image SegmentationSemantic Segmentation

  2. AMN: An Adaptive Multi-Scale Fusion Network with Boundary and Uncertainty Modeling for Nuclei Segmentation

    May 31, 2026Spoorthi M, Suja PalaniswamyHistopathology Image SegmentationHybrid CNN-Transformer Architectures

  3. Single-Channel Tissue Segmentation via Cross-Modal Distillation from Foundation Models

    May 30, 2026Sakib Mohammad, Jarin Ritu, Md Sakhawat HossainCross-Modal Knowledge DistillationFluorescence Microscopy

  4. Pre-Deployment Robustness Stress Testing for CT Segmentation Systems Using Clinically Motivated Multi-Corruption Augmentation

    May 30, 2026CholMin Kanga, Jonghyun Chung, Amanpreet Kaur +2Image Corruption RobustnessData Augmentation

  5. LegSegNet: A Public Deep Learning System for Lower Extremity CT Tissue Segmentation and Quantification

    May 29, 2026Yuwen Chen, Yaqian Chen, Roy Colglazier +4Medical Image AnalysisMedical Image Segmentation

  6. Geodesics with Unified Tangent-constrained Priors and Curvature Regularization

    May 28, 2026Chong Di, Li Liu, Jinglin Zhang +3Finsler GeometryMedical Image Segmentation

  7. A Novel Global Context-aware Deep Neural Network for Enhanced Brain Tumor Segmentation using Magnetic Resonance Images

    May 28, 2026Sourjya Mukherjee, Ananya Bhattacharjee, R. MuruganU-NetMedical Image Segmentation

  8. SwInception -- Local Attention Meets Convolutions

    May 28, 2026David Hagerman, Roman Naeem, Jakob Lindqvist +3Hybrid CNN-Transformer ArchitecturesEfficient ViTs

  9. Towards the automated segmentation of epicardial and mediastinal fats: A multi-manufacturer approach using intersubject registration and random forest

    May 28, 2026É. O. Rodrigues, A. Conci, F. F. C. Morais +1Medical Image Segmentation

  10. MORI-Seg: Learning Morphological Geometry for Instance Segmentation without Instance Annotations

    May 27, 2026Leiyue Zhao, Tianyu Shi, Daniel Reisenbuchler +12Image SegmentationWeakly Supervised Image Segmentation

  11. SCKAN: Structural Consensus-based KAN Prototype Learning for Semi-Supervised Pancreas Segmentation

    May 26, 2026Yuqi Liu, Yufei Chen, Wei Fu +2Prototype LearningMedical Image Segmentation

  12. Cesarean Scar Defect Segmentation in Transvaginal Ultrasound Images: a Dataset and Benchmark

    May 26, 2026Yuan Tian, Yue Li, Wei Xia +10Ultrasound Image SegmentationUltrasound Imaging

  13. Measuring Prediction Uncertainty in Neural Cellular Automata

    May 26, 2026Ario Sadafi, Michael Deutges, Nassir Navab +1Neural Cellular AutomataImage Segmentation

  14. Attenuation-Resilient Alternating Optimization for Laparoscopic Liver Landmark Detection

    May 26, 2026Lanqing Liu, Ruize Cui, Jialun Pei +4Anatomical Landmark DetectionMedical Image Segmentation

  15. Detail Consistent Stage-Wise Distillation for Efficient 3D MRI Segmentation

    May 25, 2026Mengchen Fan, Baocheng Geng, Xi Xiao +5Image SegmentationMedical Image Segmentation

  16. VesselSim: learning 3D blood vessel segmentation without expert annotations

    May 25, 2026Erin Rainville, Melissa Ananian, Tristan Mirolla +2Synthetic-to-Real Domain AdaptationSynthetic Data Augmentation

  17. MARVEL: Universal Murray's Law-informed Vessel Tree Segmentation and Topology Estimation

    May 25, 2026Yi Zhou, Thiara Sana Ahmed, Jacqueline Chua +7Retinal Vessel SegmentationMedical Image Analysis

  18. ImPartial: Multi-channel Whole-Cell Segmentation using Partial Annotations

    May 22, 2026Gunjan Shrivastava, Saad NadeemImage SegmentationWeakly Supervised Image Segmentation

  19. Exploiting Longitudinal Context in Clinician-Verified Interactive Lesion Tracking

    May 22, 2026Yannick Kirchhoff, Maximilian Rokuss, Daniel Philipp Mertens +5Interactive Medical Image SegmentationMedical Imaging

  20. SegGuidedNet: Sub-Region-Aware Attention Supervision for Interpretable Brain Tumor Segmentation

    May 21, 2026Hasaan Maqsood, Saif Ur Rehman Khan, Sebastian Vollmer +2Image SegmentationBraTS

  21. VEELA: A Clinically-Constrained Benchmark for Liver Vessel Segmentation in Computed Tomography Angiography

    May 21, 2026Ziya Ata Yazıcı, N. Sinem Gezer, İlkay Öksüz +19Medical Image SegmentationComputed Tomography

  22. Robustness of breast lesion segmentation under MRI undersampling improves with k-space-aware deep learning

    May 21, 2026Lukas T. Rotkopf, Marco Schlimbach, Julius C. Holzschuh +3Magnetic Resonance ImagingMedical Image Segmentation

  23. ConvNeXt-FD: A Fractal-Based Deep Model for Robust Biomedical Image Segmentation

    May 21, 2026Joao Batista Florindo, Amanda Pontes de Oliveira OrnelasMedical Image SegmentationConvolutional Neural Networks

  24. An Open Multi-Center Whole-Body FDG PET/CT Foundation Model for Tumor Segmentation

    May 20, 2026Xiaofeng Liu, Qianru Zhang, Thibault Marin +4Cross-Modality Medical Image SegmentationMedical Imaging Foundation Models

  25. Local-sensitive connectivity filter (ls-cf): A post-processing unsupervised improvement of the frangi, hessian and vesselness filters for multimodal vessel segmentation

    May 20, 2026Erick O Rodrigues, Lucas O Rodrigues, João HP Machado +5Retinal Vessel SegmentationMedical Image Segmentation

  26. SpineContextResUNet: A Computationally Efficient Residual UNet for Spine CT Segmentation

    May 20, 2026K S Nithurshen, Saurabh J. ShigwanEfficient Neural Network InferenceU-Net

  27. Gaze into the Details: Locality-Sensitive Enhancement for OCTA Retinal Vessel Segmentation

    May 20, 2026Tuopusen Huang, Ding Ma, Xiangqian WuMedical ImagingRetinal Vessel Segmentation

  28. Uncertainty-Guided Conservative Propagation for Structured Inference in Vessel Segmentation

    May 19, 2026Huan Huang, Michele Esposito, Chen ZhaoImage SegmentationMedical Image Segmentation

  29. Understanding Model Behavior in Monocular Polyp Sizing

    May 19, 2026Xinqi Xiong, Andrea Dunn Beltran, Junmyeong Choi +3EndoscopyMedical Image Classification