Generative Adversarial Networks
Also known as GAN
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9 papers in the last four weeks, up 13% on the four weeks before. 0.1% of all new papers.
Latest papers 96
Modern GANs often introduce adversarial supervision on intermediate generator outputs and interpret the resulting multi-stage synthesis as coarse-to-fine hierarchical generation. In this work, we challenge this interpretation. We argue that standard scale-wise adversarial supervision does not construct a proper coarse-to-fine hierarchy: each intermediate image is independently pushed toward the real distribution at its own resolution, but this scale-wise realism does not ensure that outputs across stages represent the identical generated sample. Moreover, the scale-specific image produced at each stage is not used as an explicit refinement target for the subsequent stage. Therefore, its adversarial loss can improve a scale-specific output without constraining later stages to preserve the same sample trajectory, allowing them to move toward a different sample rather than refine the previous output. We refer to this problem as a cross-scale trajectory misalignment problem. To resolve it, we propose CAT, a Cross-scale Aligned Transformer for multi-scale adversarial generation. CAT keeps the discriminator scale-wise, so each intermediate output is evaluated at its own resolution, while adding a simple generator-side consistency regularization that aligns intermediate outputs with the final output. On class-conditional ImageNet-256, CAT-H/2 achieves an FID-50K of 1.56 with one-step inference after only 60 training epochs, outperforming strong one-step GAN and diffusion/flow baselines.
Do Synthetic Brain MRIs Reliably Improve Tumour Classification? A StyleGAN2-ADA Class-Plane Augmentation Study on BRISC 2025
Generative augmentation is often proposed as a remedy for small medical-image datasets, but synthetic images are only useful when they improve downstream task performance. "Augmentation" here means synthetic supplementation: GAN-generated samples added to the real training pool, not geometric or photometric transforms of existing images. Twelve class-plane StyleGAN2-ADA generators were trained on constrained BRISC 2025 partitions to test whether their output, with or without InceptionV3 feature-space filtering, improves held-out tumour classification across three classifier families: a random forest (RF) on InceptionV3 features, a compact two-headed convolutional neural network (CNN), and MobileViTV2, a mobile hybrid convolutional-transformer. Each was evaluated at 1:1 and 1:2 real-to-synthetic ratios. An independent GPT-5.5 blind test placed gated real-versus-synthetic discrimination at 57.73% (95% CI: 54.48--60.92%) on the model-legible subset -- modestly above chance. The RF classifier did not benefit from the synthetic MRIs. The CNN showed consistent mean gains that did not survive Holm correction. MobileViTV2 showed the clearest benefit: filtered 1:1 augmentation improved tumour classification accuracy by 1.02% absolute (95% CI: 0.54--1.54%; Holm-corrected p = 0.0104). A secondary efficiency analysis found that every augmented CNN condition selected its checkpoint 42--64% earlier than baseline, while compute-matched MobileViTV2 runs reached selection after 50--67% fewer real-data epochs. Overall, augmentation utility was found to be architecture- and ratio-dependent, not guaranteed by visual fidelity alone.
Q-SYNTH: Hybrid Quantum-Classical Adversarial Augmentation for Imbalanced Fraud Detection
Credit card fraud detection is fundamentally challenged by extreme class imbalance, where fraudulent transactions are rare yet operationally critical. This imbalance often biases supervised learners toward the legitimate class, leading to high overall accuracy but weaker fraud-class recall and F1-score. This paper introduces Q-SYNTH, a hybrid classical--quantum generative adversarial framework in which a parameterized quantum circuit serves as the generator and a classical neural network serves as the discriminator. Q-SYNTH is designed for minority-class fraud synthesis in tabular data and is evaluated along two dimensions: statistical fidelity to real fraud samples and downstream performance for fraud detection. To this end, generated samples are assessed using distributional similarity measures based on Kolmogorov-Smirnov statistics and Wasserstein distances, real-vs-synthetic detectability measured by AUC-ROC, and downstream classification performance across both quantum and classical classifiers. Under the reported protocol, Q-SYNTH reduces marginal distribution mismatch relative to a classical GAN baseline while maintaining competitive downstream fraud-detection performance. Although SMOTE achieves the strongest feature-wise similarity and the classical GAN attains the highest downstream performance in several settings, Q-SYNTH offers a favorable compromise between distributional fidelity and downstream performance, supporting the feasibility of hybrid quantum augmentation for imbalanced fraud detection.
Generative Adversarial Learning from Deterministic Processes
Physical AI is being successfully applied to data which does not follow the traditional paradigm of independent and identically distributed (i.i.d.) samples. In fact, physical AI is often trained on data which is not random at all, and is instead derived from chaotic dynamical systems like turbulence. We aim to explain the empirical success of these methods using the example of generative adversarial networks (GANs), whose statistical learning theory under the i.i.d. assumption is generally well understood. We prove that it is possible, using an infinite-dimensional model of generative adversarial learning (GAL), to learn the invariant distribution of a sufficiently chaotic dynamical system from a single deterministically evolving time series of its states or measurements thereof, and give explicit rates for the convergence to the solution in terms of the Jensen-Shannon divergence.
When and Why Adversarial Training Improves PINNs: A Neural Tangent Kernel Perspective
Physics-informed neural networks (PINNs) are powerful surrogates for differential equations but are notoriously difficult to train due to spectral bias, stiffness, and poor accuracy on high-frequency or multiscale solutions. Adversarial training based on generative adversarial networks (GANs) has recently gained surprisingly strong empirical results in improving training, but the underlying mechanisms remain elusive. To this end, we propose a new analysis framework for adversarially trained PINNs, based on the key observation of how the discriminator in GANs can influence the training dynamics of PINNs. The framework first provides a much needed theoretical grounding to why and when adversarial training is effective in PINNs, then presents a unified analysis of GANs variants in such training, and finally leads to a new, practical, efficient training algorithm for PINNs. Empirical results demonstrate that our method can significantly reduce the pathology of PINNs training, thereby providing better models with superior performances, often several magnitudes more accurate than alternative methods.
Generative Deep Learning for Computational Destaining and Restaining of Unregistered Digital Pathology Images
Conditional generative adversarial networks (cGANs) have enabled high-fidelity computational staining and destaining of hematoxylin and eosin (H&E) in digital pathology whole-slide images (WSI). However, their ability to generalize to out-of-distribution WSI across institutions without retraining remains insufficiently characterized. Previously developed cGAN models trained on 102 registered prostate core biopsy WSIs from Brigham and Women's Hospital were evaluated on 82 spatially unregistered WSIs acquired at Stanford University. To mitigate domain shift without retraining, a preprocessing pipeline consisting of histogram-based stain normalization for H&E-stained WSIs and channel-wise intensity calibration for unstained WSIs was developed. Because image registration was intentionally omitted for real-world deployment conditions, the reported quantitative results are conservative lower bounds reflecting both model performance and limited spatial alignment. Under these conditions, virtual destaining achieved a Pearson correlation coefficient (PCC) of 0.854, structural similarity index measure (SSIM) of 0.699, and peak signal-to-noise ratio (PSNR) of 18.41 dB. H&E restaining from computationally destained outputs outperformed direct staining from ground-truth unstained inputs across all metrics (PCC: 0.798 vs. 0.715; SSIM: 0.756 vs. 0.718; PSNR: 20.08 vs. 18.51 dB), suggesting that preprocessing quality may be more limiting than model capacity. Qualitative pathological review indicated preservation of benign glandular structures while showing that malignant glands were often rendered with vessel-like morphologies. These findings support the feasibility of applying cGAN-based computational H&E staining and destaining generative models to external WSI datasets using preprocessing-based adaptation alone while defining specific morphological targets for future domain adaptation.
FSCM: Frequency-Enhanced Spatial-Spectral Coupled Mamba for Infrared Hyperspectral Image Colorization
Thermal infrared imaging is robust to illumination variations and smoke interference, making it important for all-weather perception. However, the lack of natural color and fine texture limits target recognition, human visual interpretation, and the transfer of visible-light models. Existing infrared colorization methods mainly rely on single-band images, where insufficient spectral cues may lead to structural distortion and semantic confusion. Although infrared hyperspectral images provide rich spectral responses and material information, existing single-band frameworks remain limited in modeling spatial-spectral coupling and weak texture details. To address these issues, this paper presents FSCM, a spectral-information-guided GAN framework. Within FSCM, a frequency-enhanced spatial-spectral state-space generator composed of cascaded FSB units is constructed. Each FSB integrates three complementary components: state-space modeling captures global spatial-spectral dependencies; the frequency enhancement module (FEM) combines multi-level wavelet decomposition and Fourier gating to recover structural contours, directional high-frequency details, and global frequency responses; and the dual-stream hybrid gating module (DGM) integrates deformation-aware sampling with sparse attention to enhance effective local structures and suppress background interference. Additionally, an online semantic segmentation-guided loss is introduced to constrain the generated results, improving semantic consistency in complex road scenes. Experiments show that FSCM outperforms existing infrared colorization methods in visual quality and semantic fidelity.
Cross Modality Image Translation In Medical Imaging Using Generative Frameworks
Magnetic Resonance Imaging (MRI), Computed Tomography (CT), and Positron Emission Tomography (PET) provide complementary information about tissues. Medical image-to-image (I2I) translation enables virtual scanning by synthesizing a target modality from a source one without requiring an additional acquisition. Despite growing interest, many methods operate on 2D slices, are evaluated on isolated tasks under different experimental settings, and lack clinically oriented assessment. This work presents a reproducible benchmark for 3D I2I translation in oncological imaging that compares seven generative models: three Generative Adversarial Networks (Pix2Pix, CycleGAN, and SRGAN) and four latent models (Latent Diffusion Model, Latent Diffusion Model+ControlNet, Brownian Bridge, and Flow Matching). The benchmark comprises 77 experiments across eleven configurations drawn from five datasets, covering three anatomical regions (head/neck, lung, and pelvis) and four translation directions (cone-beam CT to CT, MRI to CT, CT to PET, and T2-weighted MRI to T2-FLAIR). Under the evaluated configurations, SRGAN achieves the highest quantitative image fidelity across all tasks, while latent models perform less well, due to information loss introduced by the variational autoencoder. A tumor-level analysis reveals that all models struggle with small lesions and that, in CT to PET synthesis, models reproduce tumor shape more reliably than tracer uptake values. A Visual Turing test involving 17 physicians, including 15 radiologists, shows near-chance classification accuracy (56.7%), suggesting that experts struggle to distinguish real from synthetic volumes under the viewing conditions of the study. Expert preferences do not follow quantitative rankings, exposing a dissociation between quantitative metrics and clinical preference.
Assessment of cloud and associated radiation fields from a GAN stochastic cloud subcolumn generator
Modern Earth System Models (ESMs) operate on horizontal scales far larger than typical cloud features, requiring stochastic subcolumn generators to represent subgrid horizontal and vertical cloud variability. Traditional physically-based generators often rely on analytical cloud overlap paradigms, such as exponential-random decorrelation, which can struggle to capture the complex, anti-correlated behavior of non-contiguous cloud layers. In this study, we introduce a novel two-stage machine learning subcolumn generator for the GEOS atmospheric model, utilizing a Conditional Variational Autoencoder combined with a Generative Adversarial Network (CVAE-GAN) and a U-Net architecture. Trained on a merged CloudSat-CALIPSO height-resolved cloud optical depth dataset, the ML generator creates 56 stochastic subcolumns representing cloud occurrence and optical depth profiles. Evaluated against the established Räisänen, the ML approach accurately reproduces bimodal cloud overlap distributions, significantly reduces biases in grid-mean statistics, and halves the root-mean-square error in ISCCP-style cloud-top pressure and optical thickness joint histograms. The improvements brought by our deep generative models translate into more accurate offline radiative transfer calculations, reducing the global-mean shortwave top-of-atmosphere cloud radiative effect bias by a factor of three. Provided that the generator can be accelerated on CPUs, this offers a practical pathway to reduce structural errors at the cloud-radiation interface.
Extended Wasserstein-GAN Approach to Causal Distribution Learning: Density-Free Estimation and Minimax Optimality
Distributional causal inference requires estimating not only average treatment effects but also interventional outcome distributions, including quantiles, tail risks, and policy-dependent uncertainty. As a method for distributional causal inference, generative adversarial network (GAN)-based counterfactual methods are flexible tools for this task. However, these methods have several limitations. First, the objectives of certain techniques do not coincide with the statistical risk of the identifiable causal target, and therefore provide limited theoretical guarantees regarding estimable counterfactual distributions or optimality. Second, they tend to rely on unstable density-based methods, such as density ratio estimation. In this paper, we propose GANICE (GAN for Interventional Conditional Estimation) with several advantages: it (i) clarifies the conditional interventional distribution for each treatment--covariate state as the causal estimation target; (ii) estimates the conditional distribution such that its averaged Wasserstein risk is minimized; (iii) establishes minimax optimality. GANICE achieves these advantages through the introduction of the extended Wasserstein distance, the incorporation of a cellwise critic in its dual, and an optimality proof based on Besov space theory. Our experiments demonstrate that GANICE consistently outperforms existing methods.
Improving Generative Adversarial Networks with Self-Distillation
In modern GANs, maintaining an Exponential Moving Average (EMA) of the generator's weights is a standard practice, as such an averaged model consistently outperforms the actively trained generator. However, the EMA generator is used for final deployment only and does not influence the training process. To address this missed opportunity, we introduce Self-Distilled GAN (SD-GAN) that employs the EMA generator as a teacher to guide the active generator (student) via perceptual loss. We prove the local asymptotic stability of SD-GAN in the Dirac-GAN setting and show that it dampens the parasitic cycling behavior that plagues the conventional GANs. Empirical evaluations across established architectures and datasets demonstrate that SD-GAN improves the final image quality on several metrics (FID and random-FID in particular), stabilizes the optimization trajectory and provides additional learning guidance that is not trivially correlated with the conventional adversarial loss. It also proves effective for fine-tuning pretrained GAN models.
NeuroGAN-3D: Enhancing Intrinsic Functional Brain Networks via High-Fidelity 3D Generative Super-Resolution
Recent advances in neuroimaging have deepened our understanding of the brain's complex functional and structural organization. Among these, functional Magnetic Resonance Imaging (fMRI) - particularly resting-state fMRI (rs-fMRI) - has emerged as a tool for identifying biomarkers of intrinsic brain connectivity and delineating large-scale neural networks. These networks are typically represented as volumetric spatial maps that capture functionally coherent brain regions and reflect individual differences in brain activity and structure. The spatial resolution of these maps plays an important role, as it determines the ability to localize functional units with precision, perform reliable brain parcellation, and detect subtle, spatially specific neurobiological alterations associated with development, aging, or disease. Therefore, improving the effective resolution of neuroimaging-derived maps holds significant promise for enabling more detailed insights into brain architecture and its relationship to behavior and pathology. To address this need, we propose NeuroGAN-3D, a novel 3D generative super-resolution model tailored to the computational demands of volumetric neuroimaging. Our model leverages a generative adversarial network architecture to enhance the spatial resolution of rs-fMRI spatial maps, significantly outperforming a conventional baseline.
A Paired Point-of-Care Ultrasound Dataset for Image Quality Enhancement and Benchmarking via a cGAN Baseline
Purpose: We aim to enhance the image quality of point-of-care ultrasound (POCUS) devices using deep learning and a novel paired dataset of POCUS and high-end ultrasound images. Approach: We collected the first accurately paired dataset using a custom-built automated gantry system of low-end POCUS and high-end ultrasound images. A conditional generative adversarial network (cGAN) was utilized based on the pix2pix architecture, with a U-Net generator that incorporates both L1 and structural similarity index (SSIM) losses to improve perceptual quality. Pretraining on a simulation dataset further boosts performance. Evaluation was performed on 1064 paired ex vivo tissue and phantom ultrasound image sets. Results: Our approach improves the SSIM from 0.29 to 0.54 and PSNR from 19.16 dB to 22.41 dB. No-reference metrics also indicate substantial enhancement, with the Natural Image Quality Evaluator (NIQE) and Perception-based Image Quality Evaluator (PIQE) scores dropping from 7.95 to 4.44 and 31.12 to 19.99, respectively. Conclusions: This work presents the first publicly available accurately paired dataset of low-end POCUS to high end ultrasound images. Additionally, our results demonstrate the potential of the proposed framework to overcome hardware limitations of handheld POCUS, enhancing its diagnostic value in low-resource and point-of-care settings. The POCUS-IQ Dataset is publicly available at https://github.com/NKI-MedTech-AI/POCUS-IQ.
Hybrid Quantum-Classical GANs for the Generation of Adversarial Network Flows
Classical generative adversarial networks (GANs) have been applied to generate adversarial network traffic capable of attacking intrusion detection systems, but they suffer from shortcomings such as the need for large amounts of high-dimensional datasets, mode collapse, and high computational overhead. In this work, we propose a hybrid quantum-classical GAN (QC-GAN) framework where a variational quantum generator is used to generate synthetic network traffic flows mimicking malicious traffic using latent representations. Instead of sampling classical noise vectors, we encode the latent vector (the hidden features) as a quantum state, which is the basis for claiming more expressive latent representations and reducing computational overhead. A classical discriminator will be trained on real-world datasets (UNSW-NB15) and the proposed QC-GAN-generated fake network flows. In this configuration, the generator aims to minimize the discriminator's ability to distinguish real from fake traffic, while the discriminator aims to maximize its classification accuracy, in an iterative manner. In our attack model, we assume that the attacker is a state actor with access to limited quantum computing power, whereas the discriminator is chosen to be classical, as will likely be the case for most end users and organizations. We test the generated flows using classical intrusion detection system (IDS) models, such as a random forest classifier and a convolutional neural network-based classifier, for their ability to bypass the detection process. This work aims to highlight the possibilities of quantum machine learning as a means of generating advanced attack flows and stress testing classical IDS. Lastly, we further evaluate how hardware-based noise affects these attacks to offer a new perspective on IDS, highlighting the need for a quantum resilient defense system.
3D Ultrasound-Derived Pseudo-CT Synthesis Using a Transformer-Augmented Residual Network for Real-Time Operator Guidance
Computed tomography (CT) is indispensable for clinical diagnosis and image-guided interventions but exposes patients to ionizing radiation, motivating the development of safer imaging alternatives. Ultrasound (US) is non-ionizing and widely accessible; however, it is highly operator dependent and lacks quantitative tissue characterization, often leading to diagnostic uncertainty and unnecessary CT examinations. This work presents a 3D ultrasound-derived pseudo-CT (UD-pCT) framework that generates CT-like anatomical reference volumes inferred from US, without aiming to reproduce physically accurate Hounsfield Units. Paired 3D kidney US and CT volumes from the TRUSTED dataset are first spatially aligned using a landmark-based multimodal registration pipeline, creating high-quality paired inputs for supervised training of an adversarial framework. The proposed Bottleneck Transformer Residual U-Net3D (BT-ResUNet3D) model employs a 3D residual encoder-decoder generator augmented with a transformer bottleneck, enabling effective modeling of fine-grained local anatomical structures as well as long-range volumetric dependencies, while a 3D Conditional PatchGAN discriminator enforces local structural realism in the synthesized pseudo-CT volumes. Quantitative evaluation using PSNR and SSIM demonstrates that the proposed method outperforms established baselines in structural fidelity and perceptual image quality. The UD-pCT volumes provide real-time anatomical reference for operator guidance, potentially reducing acquisition variability and unnecessary CT use. A limitation of this study is the relatively small paired dataset, which may limit the generalizability of the proposed model.
Robustness and Transferability of Pix2Geomodel for Bidirectional Facies Property Translation in a Complex Reservoir
Reservoir geomodeling is central to subsurface characterization, but it remains challenging because conditioning data are sparse, geological heterogeneity is strong, and conventional geostatistical workflows often struggle to capture nonlinear relationships between facies and petrophysical properties. This study evaluates the robustness and transferability of Pix2Geomodel on a different and more complex reservoir dataset with reduced vertical support. The new case includes a heterogeneous reservoir-quality classification and only 54 retained layers, providing a stricter test of whether Pix2Pix-based image-to-image translation can preserve facies-property relationships under constrained data conditions. Facies, porosity, permeability, and clay volume (VCL) were extracted from a reference reservoir model, exported as aligned two-dimensional slices, augmented using consistent geometric transformations, and assembled into paired image datasets. Six bidirectional tasks were evaluated: facies to porosity, facies to permeability, facies to VCL, porosity to facies, permeability to facies, and VCL to facies. The Pix2Pix model, consisting of a U-Net generator and PatchGAN discriminator, was evaluated using image-based metrics, visual comparison, and variogram-based spatial-continuity validation. Results show that the model preserves the dominant geological architecture and main spatial-continuity trends. Facies to porosity achieved the highest pixel accuracy and frequency-weighted intersection over union of 0.9326 and 0.8807, while VCL to facies achieved the highest mean pixel accuracy and mean intersection over union of 0.8506 and 0.7049. These findings show that Pix2Geomodel can transfer beyond its original case study as a practical framework for rapid bidirectional facies-property translation in complex reservoir modeling.
Cross-Domain Adversarial Augmentation: Stabilizing GANs for Medical and Handwriting Data Scarcity
Generative Adversarial Networks (GANs) can help overcome data scarcity in computer vision tasks by generating additional training samples. In this work, we explore generative data augmentation in two low-resource domains: Bangla handwritten character recognition and chest X-ray image analysis. We use DCGAN-based models trained on 64x64 images to generate synthetic samples and evaluate their quality using Inception Score (IS), Fréchet Inception Distance (FID), and visualization methods such as t-SNE and UMAP. To measure practical usefulness, we train image classifiers using real data and a combination of real and synthetic data. Experimental results show that synthetic augmentation improves data diversity and consistently increases classification performance in limited-data settings. We also investigate training stability techniques, including gradient penalty and spectral normalization, and perform ablation studies on synthetic-to-real data ratios and sample filtering strategies. In addition, we discuss challenges related to medical image evaluation, dataset licensing, and privacy concerns of synthetic data. Our approach is simple, reproducible, and provides a strong baseline for generative augmentation in resource-constrained imaging applications.
SRGAN-CKAN: Expressive Super-Resolution with Nonlinear Functional Operators under Minimal Resources
Single-Image Super-Resolution (SISR) aims to reconstruct a High-Resolution (HR) image from a Low-Resolution (LR) observation, a fundamentally ill-posed problem where high-frequency details are severely degraded at large upscaling factors. Recent advances have been driven by transformer-based architectures and diffusion models improve global context modeling and perceptual quality at the cost of increased computational complexity. In contrast, this work focuses on enhancing the expressivity of local operators under minimal resources. We propose SRGAN--CKAN, a hybrid super-resolution framework that integrates Convolutional Kolmogorov--Arnold Networks (CKAN) into an adversarial learning setting reformulating convolution as a nonlinear patch-based transformation. The proposed operator replaces linear local mappings with spline-based functional representations, allowing expressive modeling of complex local structures and high-frequency textures using minimal hardware resources. Experimental results demonstrate that the proposed approach improves perceptual quality while preserving reconstruction fidelity, achieving a favorable balance between distortion-based and perceptual metrics. These results are obtained under constrained computational settings, highlighting the efficiency of the proposed formulation. Overall, this work introduces a complementary direction to existing approaches by improving the representational power of local transformations, providing an efficient and scalable alternative to globally intensive architectures.
Improving Diversity in Black-box Few-shot Knowledge Distillation
Knowledge distillation (KD) is a well-known technique to effectively compress a large network (teacher) to a smaller network (student) with little sacrifice in performance. However, most KD methods require a large training set and internal access to the teacher, which are rarely available due to various restrictions. These challenges have originated a more practical setting known as black-box few-shot KD, where the student is trained with few images and a black-box teacher. Recent approaches typically generate additional synthetic images but lack an active strategy to promote their diversity, a crucial factor for student learning. To address these problems, we propose a novel training scheme for generative adversarial networks, where we adaptively select high-confidence images under the teacher's supervision and introduce them to the adversarial learning on-the-fly. Our approach helps expand and improve the diversity of the distillation set, significantly boosting student accuracy. Through extensive experiments, we achieve state-of-the-art results among other few-shot KD methods on seven image datasets. The code is available at https://github.com/votrinhan88/divbfkd.
Geometry Preserving Loss Functions Promote Improved Adaptation of Blackbox Generative Model
Adaptation of blackbox generative models has been widely studied recently through the exploration of several methods including generator fine-tuning, latent space searches, leveraging singular value decomposition, and so on. However, adapting large-scale generative AI tools to specific use cases continues to be challenging, as many of these industry-grade models are not made widely available. The traditional approach of fine-tuning certain layers of a generative network is not feasible due to the expense of storing and fine-tuning generative models, as well as the restricted access to weights and gradients. Recognizing these challenges, we propose a novel end-to-end pipeline aimed at domain adaptation by leveraging geometry-preserving loss functions in conjunction to pre-trained generative adversarial networks (GANs). Our method rethinks the problem of adaptation by re-contextualizing the role of GAN inversion in obtaining accurate latent space representations. Extending the ability of existing state-of-the-art inverters, we preserve pair-wise distances between tangent spaces to successfully train a latent generative model to produce samples from the target distribution. We evaluate our proposed pipeline on StyleGANs with real distribution shifts and demonstrate that the introduction of the geometry preserving loss function lends to improved adaptation of generative models compared to other traditional loss functions.
A Wasserstein GAN-based climate scenario generator for risk management and insurance: the case of soil subsidence
According to the United Nations Office for Disaster Risk Reduction (2025), the average annual cost of natural catastrophes increased from 70--80 billion USD between 1970 and 2000 to 180--200 billion USD between 2001 and 2020. Reports from organizations such as the IFOA and the WWF highlight the need for the insurance sector to adapt to this rapidly evolving context by developing medium- to long-term strategies that go beyond the one-year horizon of prudential regulations such as Solvency II. This paper introduces an artificial intelligence framework based on Conditional Generative Adversarial Networks (Conditional GANs) to generate future spatio-temporal trajectories of climatic indices. The approach focuses on the Soil Wetness Index (SWI), a key indicator used in France to assess drought severity. Drought accounts for approximately 30% of the indemnities paid under the French natural catastrophe insurance scheme. The proposed model, SwiGAN, simulates plausible drought propagation patterns up to 2050 for a region of France particularly exposed to this hazard. By generating realistic sequences of SWI maps, SwiGAN provides insights into drought dynamics under climate change scenarios and supports the design of adaptive risk management and insurance strategies. The methodology is also generalizable to other climate-related perils and actuarial applications such as economic scenario generation.
MD-Face: MoE-Enhanced Label-Free Disentangled Representation for Interactive Facial Attribute Editing
GAN-based facial attribute editing is widely used in virtual avatars and social media but often suffers from attribute entanglement, where modifying one face attribute unintentionally alters others. While supervised disentangled representation learning can address this, it relies heavily on labeled data, incurring high annotation costs. To address these challenges, we propose MD-Face, a label-free disentangled representation learning framework based on Mixture of Experts (MoE). MD-Face utilizes a MoE backbone with a gating mechanism that dynamically allocates experts, enabling the model to learn semantic vectors with greater independence. To further enhance attribute entanglement, we introduce a geometry-aware loss, which aligns each semantic vector with its corresponding Semantic Boundary Vector (SBV) through a Jacobian-based pushforward method. Experiments with ProGAN and StyleGAN show that MD-Face outperforms unsupervised baselines and competes with supervised ones. Compared to diffusion-based methods, it offers better image quality and lower inference latency, making it ideal for interactive editing.
Pairing Regularization for Mitigating Many-to-One Collapse in GANs
Mode collapse remains a fundamental challenge in training generative adversarial networks (GANs). While existing works have primarily focused on inter-mode collapse, such as mode dropping, intra-mode collapse-where many latent variables map to the same or highly similar outputs-has received significantly less attention. In this work, we propose a pairing regularizer jointly optimized with the generator to mitigate the many-to-one collapse by enforcing local consistency between latent variables and generated samples. We show that the effect of pairing regularization depends on the dominant failure mode of training. In collapse-prone regimes with limited exploration, pairing encourages structured local exploration, leading to improved coverage and higher recall. In contrast, under stabilized training with sufficient exploration, pairing refines the generator's induced data density by discouraging redundant mappings, thereby improving precision without sacrificing recall. Extensive experiments on both toy distributions and real-image benchmarks demonstrate that the proposed regularizer effectively complements existing stabilization techniques by directly addressing intra-mode collapse.
Applications of deep generative models to DNA reaction kinetics and to cryogenic electron microscopy
This dissertation explores how deep generative models can advance the analysis of challenging biological problems by integrating domain knowledge with deep learning. It focuses on two areas: DNA reaction kinetics and cryogenic electron microscopy (cryo-EM). In the first part, we present ViDa, a biophysics-informed framework leveraging variational autoencoders (VAEs) and geometric scattering transforms to generate biophysically-plausible embeddings of DNA reaction kinetics simulations. These embeddings are reduced to a two-dimensional space to visualize DNA hybridization and toehold-mediated strand displacement reactions. ViDa preserves structure and clusters trajectory ensembles into reaction pathways, making simulation results more interpretable and revealing new mechanistic insights. In the second part, we address key challenges in cryo-EM density map interpretation and protein structure modeling. We provide a comprehensive review and benchmarking of deep learning methods for atomic model building, with improved evaluation metrics and practical guidance. We then present Struc2mapGAN, a generative adversarial network that synthesizes high-fidelity experimental-like cryo-EM density maps from protein structures. Finally, we present CryoSAMU, a structure-aware multimodal U-Net that enhances intermediate-resolution cryo-EM maps by integrating density features with structural embeddings from protein language models via cross-attention. Overall, these contributions demonstrate the potential of deep generative models to interpret DNA reaction mechanisms and advance cryo-EM density map analysis and protein structure modeling.
IncepDeHazeGAN: Novel Satellite Image Dehazing
Dehazing is a technique in computer vision for enhancing the visual quality of images captured in cloudy or foggy conditions. Dehazing helps to recover clear, high-quality images from haze-affected remote sensing data. In this study, we introduce IncepDeHazeGAN, a novel Generative Adversarial Network (GAN) involving Inception block and multi-layer feature fusion for the task of single-image dehazing. Utilizing the Inception block allows for multi-scale feature extraction. On the other hand, the multi-layer feature fusion design achieves efficient reuse of features as the features extracted at different convolution layers are fused several times. Grad-CAM XAI technique has been applied to our network, highlighting the regions focused on by the network for dehazing and its adaptation to different haze conditions. Experiments demonstrate that our network achieves state-of-the-art results in several datasets.
Enhancing Hazy Wildlife Imagery: AnimalHaze3k and IncepDehazeGan
Atmospheric haze significantly degrades wildlife imagery, impeding computer vision applications critical for conservation, such as animal detection, tracking, and behavior analysis. To address this challenge, we introduce AnimalHaze3k a synthetic dataset comprising of 3,477 hazy images generated from 1,159 clear wildlife photographs through a physics-based pipeline. Our novel IncepDehazeGan architecture combines inception blocks with residual skip connections in a GAN framework, achieving state-of-the-art performance (SSIM: 0.8914, PSNR: 20.54, and LPIPS: 0.1104), delivering 6.27% higher SSIM and 10.2% better PSNR than competing approaches. When applied to downstream detection tasks, dehazed images improved YOLOv11 detection mAP by 112% and IoU by 67%. These advances can provide ecologists with reliable tools for population monitoring and surveillance in challenging environmental conditions, demonstrating significant potential for enhancing wildlife conservation efforts through robust visual analytics.
Synthetic data in cryptocurrencies using generative models
Data plays a fundamental role in consolidating markets, services, and products in the digital financial ecosystem. However, the use of real data, especially in the financial context, can lead to privacy risks and access restrictions, affecting institutions, research, and modeling processes. Although not all financial datasets present such limitations, this work proposes the use of deep learning techniques for generating synthetic data applied to cryptocurrency price time series. The approach is based on Conditional Generative Adversarial Networks (CGANs), combining an LSTM-type recurrent generator and an MLP discriminator to produce statistically consistent synthetic data. The experiments consider different crypto-assets and demonstrate that the model is capable of reproducing relevant temporal patterns, preserving market trends and dynamics. The generation of synthetic series through GANs is an efficient alternative for simulating financial data, showing potential for applications such as market behavior analysis and anomaly detection, with lower computational cost compared to more complex generative approaches.
HyPER-GAN: Hybrid Patch-Based Image-to-Image Translation for Real-Time Photorealism Enhancement in Game Engines
Generative models are increasingly used in video game engines to enhance the photorealism of rendered images for visual synthetic data generation and simulation applications. However, they often introduce artifacts that alter the content of the original rendered scenes and require high computational resources, which limit their utilization for the photorealism enhancement of training and evaluation data, as well as their integration in the rendering pipelines of game engines. In this paper, we propose Hybrid Patch Enhanced Realism Generative Adversarial Network (HyPER-GAN), a hybrid image-to-image translation framework that is based on a lightweight U-Net-style generator capable of performing real-time inference. The framework is trained using paired rendered and photorealism-enhanced images, complemented by a novel hybrid training strategy that incorporates matched patches from unpaired real-world images to improve content preservation and further enhance the visual realism that can be achieved by the lightweight generator. Experimental results demonstrate that HyPER-GAN achieves a 6x increase in frames per second at 1080p in comparison with state-of-the-art lightweight paired image-to-image translation methods, while also increasing, in both within- and cross-engine evaluations, the photorealism of the rendered images without significantly compromising semantic consistency. Moreover, it is illustrated that HyPER-GAN maintains temporal consistency and that the proposed hybrid training strategy improves content preservation and visual realism in within-engine and increases the robustness in cross-engine evaluations compared to training the framework solely with paired rendered and photorealism-enhanced images. Code and pretrained models are publicly available at: https://github.com/stefanos50/HyPER-GAN
Scaling Quantum Machine Learning without Tricks: Full-Resolution and Diverse Image Generation
Quantum generative modeling is a rapidly evolving discipline at the intersection of quantum computing and machine learning. Contemporary quantum machine learning is generally limited to toy examples or heavily restricted datasets with few elements. This is not only due to the current limitations of available quantum hardware but also due to the absence of inductive biases arising from application-agnostic designs. Current quantum solutions must resort to tricks to scale down high-resolution images, such as relying heavily on dimensionality reduction or utilizing multiple quantum models for low-resolution image patches. Building on recent developments in classical image loading to quantum computers, we circumvent these limitations and train quantum Wasserstein GANs on the established classical MNIST and Fashion-MNIST datasets. Using the complete datasets, our system generates full-resolution images across all ten classes and establishes a new state-of-the-art performance with a single end-to-end quantum generator without tricks. As a proof-of-principle, we also demonstrate that our approach can be extended to color images, exemplified on the Street View House Numbers dataset. We analyze how the choice of variational circuit architecture introduces inductive biases, which crucially unlock this performance. Furthermore, enhanced noise input techniques enable highly diverse image generation while maintaining quality. Finally, we show promising results even under quantum shot noise conditions.
PCP-GAN: Property-Constrained Pore-scale image reconstruction via conditional Generative Adversarial Networks
Obtaining truly representative pore-scale images that match bulk formation properties remains a fundamental challenge in subsurface characterization, as natural spatial heterogeneity causes extracted sub-images to deviate significantly from core-measured values. This challenge is compounded by data scarcity, where physical samples are only available at sparse well locations. This study presents a multi-conditional Generative Adversarial Network (cGAN) framework that generates representative pore-scale images with precisely controlled properties. The framework was trained on thin section samples from four depths (1879.50-1943.50 m) of a carbonate formation, simultaneously conditioning on porosity and depth within a single model. It processes RGB thin section images that preserve critical mineralogical information (anhydrite-dolomite differentiation, grain boundaries, porosity distinctions) lost in conventional grayscale representations, capturing characteristics from grainstone fabrics to crystalline textures with anhydrite inclusions. The model achieved strong porosity control (R^2 = 0.95) across all formations with mean absolute errors of 0.0099-0.0197. Morphological validation confirmed preservation of average pore radius, specific surface area, and tortuosity within acceptable tolerances. Two-point correlation (S2) analysis confirmed that generated images preserve the spatial continuity and characteristic length scales of natural pore networks, with results consistent across the imaging resolutions tested (1.8-3.0 micron/pixel). Validated against core sample properties, generated images showed higher property fidelity with dual-constraint errors of 1.9-12.4% compared to 37.5-713.6% for randomly extracted real sub-images. This capability provides practical tools for subsurface characterization, particularly valuable for carbon storage, geothermal energy, and groundwater management.