Medical Image Segmentation

Overview

Medical image segmentation assigns labels to pixels or voxels to outline structures such as tumors, organs, vessels, and surgical instruments, enabling quantitative analysis and clinical workflows. Common approaches include U-Net-style convolutional networks, transformers and state-space models, and promptable foundation models; work also uses anatomical and topological priors, text guidance, and generative models. To reduce reliance on dense expert labels, researchers study self-supervised pretraining, semi- and weakly supervised learning, synthetic data, and interactive annotation, while domain adaptation addresses differences across scanners, hospitals, and modalities. A central challenge is making models reliable beyond their training data: high overlap scores can conceal boundary, connectivity, small-lesion, or subgroup failures, so external validation, uncertainty estimates, and clinically relevant metrics remain important.

Latest papers

CardsList

788 papers62 papers in the last four weeks, down 29% on the four weeks before. 0.4% of all new papers.

  1. Pixel Wised Lesion Prediction on COVID-19 CT Imagery: A Comparative Analysis of Automated Image Segmentation Architectures

    May 19, 2026Sarmad Khan, Arslan Shaukat, Umer Asgher +1Medical Image SegmentationConvolutional Neural Networks

  2. ELEMENT: Multi-Modal Retinal Vessel Segmentation Based on a Coupled Region Growing and Machine Learning Approach

    May 19, 2026Erick O. Rodrigues, Aura Conci, Panos LiatsisImage SegmentationMedical Imaging

  3. Disentangling Sampling from Training Budget in Class-Imbalanced CT Body Composition Segmentation

    May 19, 2026Iason Skylitsis, Dimitrios Karkalousos, Ivana IšgumClass-Imbalanced LearningImage Segmentation

  4. X-Ray cardiac angiographic vessel segmentation based on pixel classification using machine learning and region growing

    May 19, 2026E O Rodrigues, L O Rodrigues, J J Lima +6Image SegmentationMedical Imaging

  5. Cardiac fat segmentation using computed tomography and an image-to-image conditional generative adversarial neural network

    May 19, 2026Guilherme Santos da Silva, Dalcimar Casanova, Jefferson Tales Oliva +1Medical Image Segmentation

  6. WoundFormer: Multi-Scale Spatial Feature Fusion for Multi-Class Wound Tissue Segmentation

    May 19, 2026Muhammad Ashad Kabir, Rabin DulalMulti-Scale Feature FusionMedical Image Segmentation

  7. WBCAtt+: Fine-Grained Pixel-Level Morphological Annotations for White Blood Cell Images

    May 19, 2026Satoshi Tsutsui, Winnie Pang, Shuting He +1Medical Image AnalysisMedical Image Segmentation

  8. MedFM-Robust: Benchmarking Robustness of Medical Foundation Models

    May 18, 2026Xiangxiang Cui, Tianjin Huang, Yifang Wang +2Multimodal RobustnessNeural Network Robustness

  9. Speech-Guided Multimodal Learning for Vocal Tract Segmentation in Real-Time MRI

    May 18, 2026Daiqi Liu, Lukas Mulzer, Md Hasan +11Cross-Modality Medical Image SegmentationMagnetic Resonance Imaging

  10. Lost in the Folds: When Cross-Validation Is Not a Deep Ensemble for Uncertainty Estimation

    May 18, 2026Tristan Kirscher, Markus Bujotzek, Yannick Kirchhoff +5Deep EnsemblesMedical Image Segmentation

  11. Patch-MoE Mamba: A Patch-Ordered Mixture-of-Experts State Space Architecture for Medical Image Segmentation

    May 18, 2026Diego Adame, Fabian Vazquez, Jose A. Nunez +7MambaImage Segmentation

  12. VISTA: Variance-Gated Inter-Sequence Test-Time Adaptation for Multi-Sequence MRI Segmentation

    May 17, 2026Zhipeng Deng, Jiale Zhou, Wenhan Jiang +4Multi-View ConsistencyTest-Time Adaptation

  13. RadGenome-Anatomy: A Large-Scale Anatomy-Labeled Chest Radiograph Dataset via Physically Grounded Volumetric Projection

    May 17, 2026Shuchang Ye, Mingyuan Meng, Hao Wang +2Medical ImagingMedical Image Segmentation

  14. DepthPolyp: Pseudo-Depth Guided Lightweight Segmentation for Real-Time Colonoscopy

    May 15, 2026Zhuoyu Wu, Wenhui Ou, Lexi Zhang +5EndoscopyImage Segmentation

  15. Segmentation, Detection and Explanation: A Unified Framework for CT Appearance Reasoning

    May 15, 2026Yuyuan Liu, Can Peng, Yingyu Yang +3Image SegmentationMedical VLMs

  16. Semi-MedRef: Semi-Supervised Medical Referring Image Segmentation with Cross-Modal Alignment

    May 15, 2026Yuchen Li, Zhen Zhao, Yi Liu +1Interactive Medical Image SegmentationCross-Modal Alignment

  17. Evaluation of Anatomical Shape Priors in Deep Learning-Based Cardiac Multi-Compartment Segmentation

    May 15, 2026Michael Hudler, Franz Thaler, Martin UrschlerU-NetMedical Image Segmentation

  18. Beyond Instance-Level Self-Supervision in 3D Multi-Modal Medical Imaging

    May 14, 2026Tan Pan, Shuhao Mei, Yixuan Sun +8Representation LearningMultimodal Robustness

  19. Med-DisSeg: Dispersion-Driven Representation Learning for Fine-Grained Medical Image Segmentation

    May 14, 2026Zhiquan Chen, Haitao Wang, Guowei Zou +1Image SegmentationMetric Learning

  20. SpectraFlow: Unifying Structural Pretraining and Frequency Adaptation for Medical Image Segmentation

    May 14, 2026Zhiquan Chen, Haitao Wang, Guowei Zou +1Flow MatchingImage Segmentation

  21. Towards Real-Time Autonomous Navigation: Transformer-Based Catheter Tip Tracking in Fluoroscopy

    May 14, 2026Harry Robertshaw, Yanghe Hao, Weiyuan Deng +6Medical Image SegmentationSemantic Segmentation

  22. Automatic Landmark-Based Segmentation of Human Subcortical Structures in MRI

    May 14, 2026Ahmed Rekik, R. Jarrett Rushmore, Sylvain Bouix +1Image SegmentationAnatomical Landmark Detection

  23. MedCore: Boundary-Preserving Medical Core Pruning for MedSAM

    May 13, 2026Cenwei Zhang, Suncheng Xiang, Lei YouModel CompressionImage Segmentation

  24. Optimization in Sparse 2D to Dense 3D Weakly Supervised Learning: Application to Multi-Label Segmentation of Large ex vivo MRI Data

    May 12, 2026Paul Hoareau, Kuan Yi Wang, Brandon Bujak +6Weakly Supervised Image SegmentationWeakly Supervised Semantic Segmentation

  25. SEMIR: Semantic Minor-Induced Representation Learning on Graphs for Visual Segmentation

    May 12, 2026Luke James Miller, Yugyung LeeGraph Structure LearningImage Segmentation

  26. Vision Transformer-Conditioned UNet for Domain-Adaptive Semantic Segmentation

    May 12, 2026Joel Valdivia Ortega, Tingying Peng, Marion JasninHybrid CNN-Transformer ArchitecturesVision Foundation Model Adaptation

  27. USEMA: a Scalable Efficient Mamba Like Attention for Medical Image Segmentation

    May 11, 2026Elisha Dayag, Nhat Thanh Tran, Jack XinImage SegmentationHybrid CNN-Transformer Architectures