Federated Learning

Federated learning (FL) has gained wide popularity as a collaborative learning paradigm allowing collaborative Artificial Intelligence (AI) in sensitive healthcare applications. Nevertheless, the practical implementation of FL presents technical and organizational challenges, as it generally requires complex communication infrastructures. In this context, consensus-based learning (CBL) may represent a promising alternative for collaborative learning, allowing the combination of local knowledge into a federated decision system, while potentially reducing deployment overhead. Nevertheless, a comprehensive assessment of the viability of consensus-based learning as a cost-effective and sustainable alternative to federated learning has not yet been conducted. In this work we propose an extensive benchmark of the accuracy, cost-effectiveness, and sustainability of a panel of FL and CBL methods in a wide range of collaborative medical data analysis scenarios. The benchmark includes 7 different medical datasets, encompassing 3 machine learning tasks, 8 different data modalities, and multi-centric settings involving 3 to 23 clients. Our results reveal that CBL is a cost-effective and more sustainable alternative to FL. When compared across the panel of medical datasets in the considered benchmark, CBL methods provide equivalent accuracy to the one achieved by FL. Nonetheless, CBL significantly reduces training time and communication cost (resp. 15 fold and 131 fold decrease) (p-value < 0.05). This study opens a novel perspective on the deployment of collaborative AI in real-world applications, whereas the adoption of cost-effective methods is instrumental to achieve sustainability and democratization of AI by alleviating the need for extensive computational resources.

With the rapid development of the Internet of Things (IoT), federated learning (FL) has gained increasing attention for its privacy-preserving use of distributed data. However, conventional two-tier FL architectures are poorly suited to the hierarchical and heterogeneous nature of real-world IoT systems. Hierarchical Federated Learning (HFL) introduces multi-layer aggregation to better match IoT environments, but still suffers from communication inefficiencies and performance limitations caused by large data transfers, non-IID data distributions, and uneven device participation. These challenges hinder the realization of low-latency and high-accuracy training in practical IoT deployments. To address these limitations, we propose H-FedSN for practical IoT environments. H-FedSN leverages a binary mask mechanism with shared and personalized layers to reduce communication overhead by creating a sparse network without altering original weights. To tackle data heterogeneity and imbalanced device distribution, H-FedSN incorporates personalized layers for local data adaptation and employs Bayesian aggregation with cumulative Beta distribution updates at edge and cloud levels, effectively balancing contributions from diverse client groups. Experiments on three real-world IoT datasets and MNIST under non-IID conditions show that H-FedSN reduces communication costs by up to 477 times compared to baseline methods while maintaining high accuracy, making it well-suited for hierarchical FL in IoT deployments.

Federated learning (FL) enables collaborative analysis of biomedical data without exchanging sensitive patient-level information, but its performance in multi-center studies may be compromised by batch effects which can obscure biological signals. Here, we systematically assess the impact of uncorrected batch effects on FL outcomes using four multi-center omics datasets, including transcriptomic, proteomic, and metabolomic data, and two representative algorithms: federated k-means clustering and federated random forest classification. Our results demonstrate that uncorrected batch effects undermine unsupervised FL and can substantially degrade supervised FL performance, indicating that privacy-aware batch-effect correction is essential for reliable FL. To enable privacy-preserving BEC in distributed bulk omics data, we introduce fedRBE ( https://featurecloud.ai/app/fedrbe ), a federated implementation of limma's removeBatchEffect() method enhanced by secure multi-party computation, suitable for datasets with missing values and non-identical feature sets across clients, including proteomics and metabolomics data.

Personalized collaborative learning in federated settings faces a critical trade-off between customization and participant trust. Existing approaches typically rely on centralized coordinators or trusted peer groups, limiting their applicability in open, trust-averse environments. While recent decentralized methods explore anonymous knowledge sharing, they often lack global scalability and robust mechanisms against malicious peers. To bridge this gap, we propose TPFed, a \textit{Trust-free Personalized Decentralized Federated Learning} framework. TPFed replaces central aggregators with a blockchain-based bulletin board, enabling participants to dynamically select global communication partners based on Locality-Sensitive Hashing (LSH) and peer ranking. Crucially, we introduce an ``all-in-one'' knowledge distillation protocol that simultaneously handles knowledge transfer, model quality evaluation, and similarity verification via a public reference dataset. This design ensures secure, globally personalized collaboration without exposing local models or data. Extensive experiments demonstrate that TPFed significantly outperforms traditional federated baselines in both learning accuracy and system robustness against adversarial attacks.

Federated learning (FL) is a machine learning paradigm where clients with different behaviors and preferences can learn collaboratively without compromising data privacy. Typical FL methods often rely on fixed weighting for parameter aggregation, thereby neglecting the mutual influence among clients. In practice, clients with similar preferences or backgrounds may provide more useful knowledge to each other, which can be leveraged to improve local performance. However, how to quantify such cross-client influence and how to exploit it for personalized aggregation remain underexplored. To address this gap, we propose an influence-oriented Federated learning framework which quantitatively measures Client-level and Class-level Influence to realize adaptive parameter aggregation for each client (FedC^2I for short). Our core idea is to explicitly model the inter-client influence within an FL system via the well-crafted influence vector and influence matrix. Specifically, FedC^2I incorporate influence vectors to quantify client-level influence, enables clients to selectively acquire knowledge from others, and guides the aggregation of feature representation layers. Meanwhile, the influence matrix captures class-level influence in a more fine-grained manner to achieve personalized classifier aggregation. We evaluate the performance of FedC^2I against existing federated learning methods under non-IID settings, and the results demonstrate the superiority of our method in terms of effectiveness, robustness, and interpretability.

Federated Learning (FL) emerges as a distributed machine learning approach that addresses privacy concerns by training AI models locally on devices. Decentralized Federated Learning (DFL) extends the FL paradigm by eliminating the central server, thereby enhancing scalability and robustness through the avoidance of a single point of failure. However, DFL faces significant challenges in optimizing security, as most Byzantine-robust algorithms proposed in the literature are designed for centralized scenarios. In this paper, we present a novel Byzantine-robust aggregation algorithm to enhance the security of Decentralized Federated Learning environments, coined WFAgg. This proposal handles adverse conditions and strengthens the robustness of dynamic decentralized topologies at the same time by employing multiple filters to identify and mitigate Byzantine attacks. Experimental results demonstrate the effectiveness of the proposed algorithm in maintaining model accuracy and convergence in the presence of various Byzantine attack scenarios, outperforming state-of-the-art centralized Byzantine-robust aggregation schemes (such as Multi-Krum or Clustering). These algorithms are evaluated on an IID image classification problem in both centralized and decentralized scenarios.

Previous studies on federated learning (FL) often encounter performance degradation due to data heterogeneity among different clients. In light of the recent advances in multimodal large language models (MLLMs), such as GPT-4v and LLaVA, which demonstrate their exceptional proficiency in multimodal tasks, such as image captioning and multimodal question answering. We introduce a novel federated learning framework, named Multimodal Large Language Model Assisted Federated Learning (MLLM-LLaVA-FL), which employs powerful MLLMs at the server end to address the heterogeneous and long-tailed challenges. Owing to the advanced cross-modality representation capabilities and the extensive open-vocabulary prior knowledge of MLLMs, our framework is adept at harnessing the extensive, yet previously underexploited, open-source data accessible from websites and powerful server-side computational resources. Hence, the MLLM-LLaVA-FL not only enhances the performance but also avoids increasing the risk of privacy leakage and the computational burden on local devices, distinguishing it from prior methodologies. Our framework has three key stages. Initially, we conduct global visual-text pretraining of the model. This pretraining is facilitated by utilizing the extensive open-source data available online, with the assistance of MLLMs. Subsequently, the pretrained model is distributed among various clients for local training. Finally, once the locally trained models are transmitted back to the server, a global alignment is carried out under the supervision of MLLMs to further enhance the performance. Experimental evaluations on established benchmarks, show that our framework delivers promising performance in the typical scenarios with data heterogeneity and long-tail distribution across different clients in FL.

Contemporary AI faces the challenge of balancing generality with user-specific personalization. In federated learning (FL), this challenge is amplified by highly heterogeneous client data with complex non-IID patterns beyond standard IID assumptions. Many existing FL methods are designed for relatively restricted heterogeneity settings (e.g., a fixed number of clusters or a fixed form of personalization), limiting their robustness under complex structures. In this work, we study FL from a \emph{multi-level non-IID} perspective, where client similarity is captured by multiple granularities of shared knowledge: global, subgroup, and client-specific components. This view captures coarse-to-fine relationships while requiring less prior knowledge of task boundaries. Building on this insight, we propose \emph{Federated Multi-level Additive Modeling} (FeMAM), which learns multiple levels of shareable models and constructs personalized predictors via additive composition across levels. To move beyond a fixed structure, FeMAM allows models to grow and be pruned dynamically during training, adapting to diverse federated scenarios. Despite employing multiple models, FeMAM remains cost-friendly by unlocking only a small subset (one level) of models for training at a time. Extensive experiments show that FeMAM effectively approximates diverse complex non-IID structures and consistently outperforms representative clustered and personalized FL baselines.

Local SGD is a popular optimization method in distributed learning, often outperforming other algorithms in practice, including mini-batch SGD. Despite this success, theoretically proving the dominance of local SGD in settings with reasonable data heterogeneity has been difficult, creating a significant gap between theory and practice. In this paper, we provide new lower bounds for local SGD under existing first-order data heterogeneity assumptions, showing that these assumptions are insufficient to prove the effectiveness of local update steps. Furthermore, under these same assumptions, we demonstrate the min-max optimality of accelerated mini-batch SGD, which fully resolves our understanding of distributed optimization for several problem classes. Our results emphasize the need for better models of data heterogeneity to understand the effectiveness of local SGD in practice. Towards this end, we consider higher-order smoothness and heterogeneity assumptions, providing new upper bounds that imply the dominance of local SGD over mini-batch SGD when data heterogeneity is low.

Graph clustering, an important unsupervised problem, has been shown to be more resistant to advances in Graph Neural Networks (GNNs). In addition, almost all clustering methods focus on homophilic graphs and ignore heterophily. This significantly limits their applicability in practice, since real-world graphs exhibit a structural disparity and cannot simply be classified as homophily and heterophily. Thus, a principled way to handle practical graphs is urgently needed. To fill this gap, we provide a novel solution with theoretical support. Interestingly, we find that most homophilic and heterophilic edges can be correctly identified on the basis of neighbor information. Motivated by this finding, we construct two graphs that are highly homophilic and heterophilic, respectively. They are used to build low-pass and high-pass filters to capture holistic information. Important features are further enhanced by the squeeze-and-excitation block. We validate our approach through extensive experiments on both homophilic and heterophilic graphs. Empirical results demonstrate the superiority of our method compared to state-of-the-art clustering methods.

Federated learning has emerged as a decentralized approach for training high-performance models without accessing user data. Despite its effectiveness, it is vulnerable to poisoning attacks, where malicious users manipulate the global model by uploading poisoned updates. In this paper, we propose FedReview, a review-based mechanism to identify and dispose the potential poisoned updates in federated learning. Under FedReview, the server randomly assigns a subset of clients as reviewers to evaluate model updates on their training datasets in each round. The reviewers rank the updates based on evaluation results and estimate the number of low-quality updates as potential poisoned ones. Based on the review reports, the server applies a majority voting mechanism to aggregate rankings, which tolerates wrong rankings from malicious reviewers and guides the removal of suspicious updates during model aggregation. In contrast to prior works such as FLTrust, FedReview does not require a server-side validation dataset or prior knowledge of clients, allowing flexible client participation. Extensive experiments demonstrate that FedReview enables the server to learn a well-performing global model in adversarial environments.

There are two categories of methods in Federated Learning (FL) for joint training across multiple clients: (i) parallel FL (PFL), where clients train models in a parallel manner; and (ii) sequential FL (SFL), where clients train models in a sequential manner. In contrast to that of PFL, the convergence theory of SFL on heterogeneous data is still lacking. In this paper, we establish the convergence guarantees of SFL for strongly/general/non-convex objectives on heterogeneous data. The convergence guarantees of SFL are better than that of PFL on heterogeneous data with both full and partial client participation. Experimental results validate the counterintuitive analysis result that SFL outperforms PFL on extremely heterogeneous data in cross-device settings.

Federated Learning (FL) systems are susceptible to adversarial attacks, such as model poisoning attacks and backdoor attacks. Existing defense mechanisms face critical limitations in deployments, such as relying on impractical assumptions (e.g., adversaries acknowledging the presence of attacks before attacking) or undermining accuracy in model training, even in benign scenarios. To address these challenges, we propose CustodianFL, a two-staged anomaly detection method specifically designed for FL deployments. In the first stage, it flags suspicious client activities. In the second stage that is activated only when needed, it further examines these candidates using Three-Sigma Rule to identify and exclude truly malicious local models from FL training. To ensure integrity and transparency within the FL system, CustodianFL integrates zero-knowledge proofs, enabling clients to cryptographically verify the server's detection process without relying on the server's goodwill. CustodianFL operates without unrealistic assumptions and avoids interfering with FL training in attack-free scenarios. It bridges the gap between theoretical advances in FL security and the practical demands of real FL systems. Experimental results demonstrate that CustodianFL consistently delivers performance comparable to benign cases, highlighting its effectiveness in identifying and eliminating malicious models with high accuracy.

Federated learning is a distributed machine learning technology, which realizes the balance between data privacy protection and data sharing computing. To protect data privacy, feder-ated learning learns shared models by locally executing distributed training on participating devices and aggregating local models into global models. There is a problem in federated learning, that is, the negative impact caused by the non-independent and identical distribu-tion of data across different user terminals. In order to alleviate this problem, this paper pro-poses a strengthened federation aggregation method based on adaptive OPTICS clustering. Specifically, this method perceives the clustering environment as a Markov decision process, and models the adjustment process of parameter search direction, so as to find the best clus-tering parameters to achieve the best federated aggregation method. The core contribution of this paper is to propose an adaptive OPTICS clustering algorithm for federated learning. The algorithm combines OPTICS clustering and adaptive learning technology, and can effective-ly deal with the problem of non-independent and identically distributed data across different user terminals. By perceiving the clustering environment as a Markov decision process, the goal is to find the best parameters of the OPTICS cluster without artificial assistance, so as to obtain the best federated aggregation method and achieve better performance. The reliability and practicability of this method have been verified on the experimental data, and its effec-tiveness and superiority have been proved.

Building trustworthy machine learning algorithms for biological applications requires adapting to data heterogeneity from different sources, batches, distributions, or studies. We propose the 'Cross-Cluster Weighted Forest' (CCWF), an ensembling approach that explicitly leverages heterogeneity in the feature distribution to produce more accurate and more generalizable predictors than the standard Random Forest in cases when data can be naturally clustered. CCWF generalizes the RF architecture to an outer unsupervised layer, supervised subtasks, and ensembling. Specifically it involves unsupervised clustering of the training data, fitting a Random Forest on each cluster, and combining the forests via stacked regression weights that reward cross-cluster generalizability. We provide a theoretical analysis of an analytically tractable forest model showing that cluster-based ensembling is asymptotically more accurate than training a single forest on the full data, with the gain driven by bias reduction. In simulations, we find that CCWF is robust across data-generating regimes and outcome models; furthermore, we explore the influence of data partitioning and ensemble weighting strategies on the benefits of our method. Finally, we apply our approach to cancer molecular profiling and gene expression datasets that are naturally divisible into clusters; in both simulations and real data examples, we illustrate that our approach outperforms classic Random Forest by margins of 30-40%, aligning with our theoretical results. Overall, we show that CCWF provides a statistically grounded prediction algorithm for data spanning multiple domains or sub-populations, a structure common in biological applications.

This paper integrates deep neural networks (DNNs) into structural models to increase flexibility and capture rich heterogeneity while preserving interpretability. Economic (or scientific or domain-restricted) structure and machine learning are complements in empirical modeling, not substitutes: DNNs provide the capacity to learn complex, nonlinear heterogeneity, while the structure ensures the estimates remain interpretable and suitable for decision-making and policy analysis. We start with a standard parametric structural model and then enrich its parameters into fully flexible functions, which are estimated using a DNN with the model structure built in. We illustrate our framework with an application to demand estimation in consumer choice. We show that by enriching a demand model we can capture rich heterogeneity exploit it to create personalized pricing. Optimization is not possible without structure, but cannot be heterogeneous without machine learning. The same lessons apply to precision dosing, adaptive treatment, educational testing, and other targeting settings. We provide theoretical justification for our proposed methodology: nonasymptotic bounds and a novel and general influence function for feasible inference via double machine learning, so that the latter can be easily applied in numerous new contexts. These results may be of interest in other contexts as they generalize prior work.

Federated learning (FL) enables collaborative learning of computer vision models, where privacy and regulatory constraints prevent centralizing data across devices or organizations. However, practical FL deployments often exhibit severe class imbalance and label skew, causing standard aggregation protocols to overfit dominant clients and degrade minority-class performance. We propose a data-free, class-wise contribution estimation and aggregation framework based on logit maximization (CELM) that does not require sharing raw data, client metadata, or auxiliary public datasets. The FL server probes client updates to obtain class-wise evidence scores and assembles a cross-client evidence matrix, which quantifies both per-class competence and class coverage. Using this matrix, we compute contribution weights that upweight clients providing strong, discriminative evidence for underrepresented classes. The resulting aggregation is stable due to simplex constraints and momentum smoothing, and it remains compatible with standard FL training pipelines. We evaluate the approach on representative vision benchmarks under controlled non-IID and pathological label splits, demonstrating that CELM-based aggregation improves robustness to imbalance and statistical heterogeneity, while yielding better performance without requiring any additional data exchange.

We study the application of federated learning (FL) to indoor fire detection. Such fire-detection systems use edge cameras that record sensitive footage which cannot easily be collected at a central server. Existing federated solutions leave three practical obstacles unaddressed: limited uplink bandwidth, Byzantine (malicious or faulty) clients, and unconditional trust in a single, permanently fixed aggregation server. Our main contributions address all three. In particular, we provide (i) a curated indoor fire-detection dataset assembled from eight public sources; (ii) an edge-deployable detector whose model updates are compressed up to 10 times with only a small loss in balanced accuracy; and (iii) a semi-decentralized Byzantine-robust FL method that combines history-aware aggregation with a rotating coordinator, evicting stealthy attacks that per-round filters miss while removing the fixed-server single point of failure. On the held-out test set the rotating-coordinator method matches its fixed-server counterpart in accuracy and detection speed, and a physically distributed six-node cloud deployment confirms feasibility.

We study continual pre-training (CPT) as a mechanism for adapting general-purpose large language models to specialized domains: mathematics, instruction, code, and natural text. Using singular value decomposition of weight matrices, we find that CPT leaves singular value spectra largely invariant, with adaptation driven mainly by changes in singular vectors. An analysis of attention-head projection matrices reveals strong, domain-dependent head heterogeneity, which we exploit to define a head importance criterion: up to 60% of head updates can be removed without measurable quality loss. Selectively rewinding low-importance heads to their pre-trained state improves benchmark accuracy by up to 4% versus the fully trained baseline. Finally, we identify domain connectivity - linear interpolation between CPT checkpoints yields smooth domain-quality interpolation without notable degradation on either domain - and release Diffract, an open-source toolkit for scalable spectral analysis of billion-parameter models.