Prototype Learning

Prototype-based explanations offer an intuitive, example-based approach to support the interpretability of machine learning black box classifiers but often lack feature-level granularity. We introduce a framework that integrates feature importance at two levels to address this gap. First, for local explanations, we propose \textit{alike parts}: a method that uses feature importance scores to highlight the most relevant, shared feature subsets between a classified instance and its nearest prototype, guiding user attention. Second, we augment the global prototype selection objective function with a feature importance term to actively promote diversity in the feature attributions of the selected prototypes. Experiments on six benchmark datasets show that this augmented selection process maintains or, in some cases, increases the prediction fidelity of the surrogate model, suggesting that feature diversity does not compromise model fidelity.

Segmenting images is critical for visual understanding but demands extensive pixel-level annotations. Foundational models have enabled new paradigms for predicting new classes guided by textual prompts, without annotations from the target domain. Yet, on specialized target domains, far from the original pre-training, their performance degrades. We study the errors of existing methods under such domain-shift, finding that misclassification rather than mask generation is the main culprit. To address this, we introduce the novel problem of Few-Shot Visual Adaptation for text-prompted Segmentation. This kind of adaptation has been largely studied for image classification, but it remains unexplored for segmentation. We tackle this task with Prototype Adaptation (PrAda), a novel, parameter-efficient method that adapts a frozen text-prompted segmentation model. Our approach learns class-specific prototypes by combining fine-grained pixel features and high-level transformer representations, which are then fused with the original text-based predictions through a learned importance factor. This preserves the model's zero-shot potential while enabling strong adaptation to new domains. Experiments across semantic, instance, and panoptic segmentation on five benchmarks demonstrate that PrAda yields significant improvements over state-of-the-art and proposed baselines.

Cross-view geo-localization (CVGL), which matches an oblique drone view to a geo-referenced satellite tile, has emerged as a key alternative for autonomous drone navigation when GNSS signals are jammed, spoofed, or unavailable. Despite strong recent progress, three limitations persist: (1) global-descriptor designs compress the patch grid into a single vector without separating layout from texture across the view gap; (2) altitude-related scale variation is retained in the learned embedding rather than marginalized; and (3) multi-objective training relies on hand-tuned scalars over losses on incompatible gradient scales. We propose SkyPart, a lightweight swappable head for patch-based vision transformers (ViTs) that institutes explicit part grouping over the patch grid. SkyPart has four theory-grounded components: (i) learnable prototypes competing for patch tokens via single-pass cosine assignment; (ii) altitude-conditioned linear modulation applied only during training, making the retrieval embedding altitude-free at inference; (iii) a graph-attention readout over active prototypes; and (iv) a Kendall uncertainty-weighted multi-objective loss whose stationary points are Pareto-stationary. At 26.95M parameters and 22.14 GFLOPs, SkyPart is the smallest among top-performing methods and sets a new state of the art on SUES-200, University-1652, and DenseUAV under a single-pass, no-re-ranking, no-TTA protocol. Its advantage over the strongest baseline widens under the ten-condition WeatherPrompt corruption benchmark.

Cross-domain few-shot medical image segmentation (CD-FSMIS) requires a model to generalise simultaneously to novel anatomical categories and unseen imaging domains from only a handful of annotated examples. Existing prototypical approaches inevitably entangle anatomical structure with domain-specific appearance variations, and thus lack a stable reference for reliable matching under domain shift. We observe that the geometric structure of human anatomy constitutes a reliable, domain-transferable prior that has been overlooked. Building on this insight, we propose GeoProto, a geometry-aware CD-FSMIS framework that enriches prototypical matching with explicit structural priors. The core component, Geometry-Aware Prototype Enrichment (GAPE), augments each local appearance prototype with a learned geometric offset encoding its ordinal position within the organ's interior topology. This offset is derived from an auxiliary Ordinal Shape Branch (OSB) trained under an ordinally consistent objective that enforces monotonic variation of geometric embeddings across interior strata, requiring no annotation beyond standard segmentation masks. Extensive experiments across seven datasets spanning three evaluation settings (cross-modality, cross-sequence, and cross-context) demonstrate that GeoProto achieves state-of-the-art performance.

In domains where both predictive performance and interpretability are essential, deep neural networks achieve strong results but provide limited insight into how their predictions are made. Projection-based prototype networks address this limitation by grounding predictions in similarity to representative training examples, enabling case-based explanations and global prototype inspection. However, existing approaches rely on label supervision, tying prototypes to a specific task and requiring large labeled datasets. We introduce ProtoSSL, a framework for pretraining a foundational latent prototype bank on unlabeled data and transferring it to downstream tasks to create interpretable, projection-based prototype models. Our key idea is to separate motif discovery from label alignment. ProtoSSL first learns a transferrable prototype bank using a self-supervised objective applied directly to prototype activations, and then aligns these prototypes to downstream tasks through a novel efficient assignment procedure. Across six electrocardiography (ECG) datasets, ProtoSSL improves label efficiency, outperforming supervised prototype baselines in low-data regimes with as few as 256 labeled examples; with fine-tuning, ProtoSSL outperforms supervised prototype baselines at full dataset scale. In a human evaluation study, ProtoSSL produces prototypes and prototype-based explanations that are judged more favorably than those learned with direct label supervision. We further show that the framework extends to audio classification. Thus, ProtoSSL enables both learning foundational prototypes from unlabeled data before the downstream label space is known, and subsequent assignment to new tasks to create interpretable, projection-grounded prototypes.

Open-set supervised anomaly detection (OSAD) aims to identify unseen anomalies using limited anomalous supervision. However, existing prototype-based methods typically model normal data via a unimodal Gaussian prior, failing to capture inherent multi-modality and resulting in blurred decision boundaries. To address this, we propose Mixture Prototype Flow Matching (MPFM), a framework that learns a continuous transformation from normal feature distributions to a structured Gaussian mixture prototype space. Departing from traditional flow-based approaches that rely on a single velocity vector, MPFM explicitly models the velocity field as a Gaussian mixture prior where each component corresponds to a distinct normal class. This design facilitates mode-aware and semantically coherent distribution transport. Furthermore, we introduce a Mutual Information Maximization Regularizer (MIMR) to prevent prototype collapse and maximize normal-anomaly separability. Extensive experiments demonstrate that MPFM achieves state-of-the-art performance across diverse benchmarks under both single- and multi-anomaly settings.

Digital pathology has fundamentally altered diagnostic workflows by enabling the computational analysis of gigapixel Whole Slide Images (WSIs), yet effectively deciphering their complex tumor microenvironments remains a formidable challenge. Existing Multiple Instance Learning (MIL) frameworks typically treat Whole Slide Images as unstructured bags of patches, discarding critical morphological semantics and spatial geometry. This lack of inductive bias often leads to overfitting on background noise and fails to align visual features with high-level diagnostic knowledge. To overcome these limitations, we propose the Hierarchical Prototype-based Domain Priors (HPDP) framework, a unified multimodal approach for joint histopathology diagnosis and prognosis. HPDP mitigates the data-driven "black box" issue by introducing a Morphologically Anchored Prototype System (MAPS), which anchors learning to interpretable morphological clusters, and a Sinusoidal Positional Encoder (SPE) to explicitly model tissue architecture. Furthermore, we bridge the semantic gap via a Hierarchical Cross-Modal Alignment (HCMA) module, using Large Language Model (LLM)-generated descriptions to contextually refine visual representations. Extensive experiments across seven cancer cohorts demonstrate that HPDP consistently achieves state-of-the-art performance with superior robustness and interpretability.

Visible-infrared person re-identification (VI-ReID) enables cross-modality identity matching for all-day surveillance, yet existing methods predominantly focus on the image level or rely heavily on costly identity annotations. While video-based VI-ReID has recently emerged to exploit temporal dynamics for improved robustness, existing studies remain limited to supervised settings. Crucially, the unsupervised video VI-ReID problem, where models must learn from RGB and infrared tracklets without identity labels, remains largely unexplored despite its practical importance in real-world deployment. To bridge this gap, we propose HiTPro (Hierarchical Temporal Prototyping), a prototype-driven framework without explicit hard pseudo-label assignment for unsupervised video-based VI-ReID. HiTPro begins with an efficient Temporal-aware Feature Encoder that first extracts discriminative frame-level features and then aggregates them into a robust tracklet-level representation. Building upon these features, HiTPro first constructs reliable intra-camera prototypes via Intra-Camera Tracklet Prototyping by aggregating features from temporally partitioned sub-tracklets. Through Hierarchical Cross-Prototype Alignment, we perform a two-stage positive mining process: progressing from within-modality associations to cross-modality matching, enhanced by Dynamic Threshold Strategy and Soft Weight Assignment. Finally, {Hierarchical Contrastive Learning} progressively optimizes feature-prototype alignment across three levels: intra-camera discrimination, cross-camera same-modality consistency, and cross-modality invariance. Extensive experiments on HITSZ-VCM and BUPTCampus demonstrate that HiTPro achieves state-of-the-art performance under fully unsupervised settings, significantly outperforming adapted baselines and establishes a strong baseline for future research.

Zero-shot vision-language models (VLMs) have shown promise for chest radiograph classification, but their performance is often limited by confounding label co-occurrence, long-tail class imbalance, and transfer instability under domain shift. We propose ProtoCLIP, a refinement strategy for CLIP-style VLMs that improves zero-shot discrimination through targeted data curation and distilled anchor alignment. Specifically, we construct pathology-focused training subsets with curated negative samples to reduce co-occurrence bias. We also introduce a representation-preserving distillation objective to stabilize adaptation while maintaining semantic structure and improving discrimination of clinically relevant co-occurring pathologies. Evaluated on an unseen dataset VinDr-CXR, ProtoCLIP improves AUC by 2-10 percentage points over a strong CLIP-based baseline across multiple findings. For pneumothorax specifically, ProtoCLIP achieves a state-of-the-art AUC of 0.94. These results demonstrate that anchor-guided refinement, coupled with curated supervision and controlled adaptation, can mitigate common zero-shot transfer failures in medical VLMs without requiring large-scale retraining.

Remote sensing segmentation in real deployment is inherently continual: new semantic categories emerge, and acquisition conditions shift across seasons, cities, and sensors. Despite recent progress, many incremental approaches still treat training steps as isolated updates, which leaves representation drift and forgetting insufficiently controlled. We present ProtoFlow, a time-aware prototype dynamics framework that models class prototypes as trajectories and learns their evolution with an explicit temporal vector field. By jointly enforcing low-curvature motion and inter-class separation, ProtoFlow stabilizes prototype geometry throughout incremental learning. Experiments on standard class- and domain-incremental remote sensing benchmarks show consistent gains over strong baselines, including up to 1.5-2.0 points improvement in mIoUall, together with reduced forgetting. These results suggest that explicitly modeling temporal prototype evolution is a practical and interpretable strategy for robust continual remote sensing segmentation. Open-source code:https://github.com/dudududke/protoflow.

Electroencephalography (EEG)-based emotion recognition remains challenging in cross-subject settings due to severe inter-subject variability. Existing methods mainly learn subject-invariant features, but often under-exploit stimulus-locked group regularities shared across subjects. To address this issue, we propose the Group Resonance Network (GRN), which integrates individual EEG dynamics with offline group resonance modeling. GRN contains three components: an individual encoder for band-wise EEG features, a set of learnable group prototypes for prototype-induced resonance, and a multi-subject resonance branch that encodes PLV/coherence-based synchrony with a small reference set. A resonance-aware fusion module combines individual and group-level representations for final classification. Experiments on SEED and DEAP under both subject-dependent and leave-one-subject-out protocols show that GRN consistently outperforms competitive baselines, while additional analyses confirm the effects of prototype learning, PLV/coherence resonance, and leakage-safe reference construction.

Time series forecasting has witnessed significant progress with deep learning. While prevailing approaches enhance forecasting performance by modifying architectures or introducing novel enhancement strategies, they often fail to dynamically disentangle and leverage the complex, intertwined temporal patterns inherent in time series, thus resulting in the learning of static, averaged representations that lack context-aware capabilities. To address this, we propose the Dual-Prototype Adaptive Disentanglement framework (DPAD), a model-agnostic auxiliary method that equips forecasting models with the ability of pattern disentanglement and context-aware adaptation. Specifically, we construct a Dynamic Dual-Prototype bank (DDP), comprising a common pattern bank with strong temporal priors to capture prevailing trend or seasonal patterns, and a rare pattern bank dynamically memorizing critical yet infrequent events, and then an Dual-Path Context-aware routing (DPC) mechanism is proposed to enhance outputs with selectively retrieved context-specific pattern representations from the DDP. Additionally, we introduce a Disentanglement-Guided Loss (DGLoss) to ensure that each prototype bank specializes in its designated role while maintaining comprehensive coverage. Comprehensive experiments demonstrate that DPAD consistently improves forecasting performance and reliability of state-of-the-art models across diverse real-world benchmarks.

Existing stylized motion generation models have shown their remarkable ability to understand specific style information from the style motion, and insert it into the content motion. However, capturing intra-style diversity, where a single style should correspond to diverse motion variations, remains a significant challenge. In this paper, we propose a clustering-based framework, ClusterStyle, to address this limitation. Instead of learning an unstructured embedding from each style motion, we leverage a set of prototypes to effectively model diverse style patterns across motions belonging to the same style category. We consider two types of style diversity: global-level diversity among style motions of the same category, and local-level diversity within the temporal dynamics of motion sequences. These components jointly shape two structured style embedding spaces, i.e., global and local, optimized via alignment with non-learnable prototype anchors. Furthermore, we augment the pretrained text-to-motion generation model with the Stylistic Modulation Adapter (SMA) to integrate the style features. Extensive experiments demonstrate that our approach outperforms existing state-of-the-art models in stylized motion generation and motion style transfer.

Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which reduces their usefulness in clinical settings. Prototype learning presents a potential solution, yet traditional methods focus on local similarities and static matching, neglecting the broader tumor context and lacking strong semantic alignment with genomic data. To overcome these issues, we introduce an innovative prototype-based multimodal framework, FeatProto, aimed at enhancing cancer survival prediction by addressing significant limitations in current prototype learning methodologies within pathology. Our framework establishes a unified feature prototype space that integrates both global and local features of whole slide images (WSI) with genomic profiles. This integration facilitates traceable and interpretable decision-making processes. Our approach includes three main innovations: (1) A robust phenotype representation that merges critical patches with global context, harmonized with genomic data to minimize local bias. (2) An Exponential Prototype Update Strategy (EMA ProtoUp) that sustains stable cross-modal associations and employs a wandering mechanism to adapt prototypes flexibly to tumor heterogeneity. (3) A hierarchical prototype matching scheme designed to capture global centrality, local typicality, and cohort-level trends, thereby refining prototype inference. Comprehensive evaluations on four publicly available cancer datasets indicate that our method surpasses current leading unimodal and multimodal survival prediction techniques in both accuracy and interpretability, providing a new perspective on prototype learning for critical medical applications. Our source code is available at https://github.com/JSLiam94/FeatProto.

Few-shot 3D point cloud semantic segmentation aims to segment novel categories using a minimal number of annotated support samples. However, prototypes derived from the limited non-structural point cloud support set are often misaligned and have a small capacity, hindering effective gen eralization to novel categories. This stems from two core issues: i) the prototype possess limited representational capacity fails to cover the full intra-class diversity of a novel category, and ii) the prototypes suffer from misalignment with the query space due to the inter-set inconsistency between support and query sets. To address these issues, our work focuses on leveraging the few support samples to construct a well-aligned big-capacity prototype. Motivated by the powerful generative capabilities of diffusion models, we re-purpose its pre-trained conditional encoder to provide rich feature components for prototype ex pansion. Subsequently, a push-pull force aligns this expanded prototype towards the query feature space. Under this setup, we introduce the Prototype Expansion Network (PENet), a framework that constructs aligned big-capacity prototypes from two complementary feature sources. Specifically, PENet employs a dual-stream learner architecture: it retains a conventional fully supervised Intrinsic Learner (IL) to distill representative features, while introducing a novel Diffusion Learner (DL) to provide rich generalizable features. The resulting dual prototypes are then processed by a Prototype Assimilation Module (PAM), which adopts a push-pull attention block to align the prototypes with the query space. Furthermore, a Prototype Calibration Mechanism (PCM) regularizes the final big-capacity prototype to prevent semantic drift. Extensive experiments on the S3DIS and ScanNet datasets demonstrate that PENet outperforms state-of-the-art methods across various few-shot settings.

Anomaly detection in medical images is challenging due to limited annotations and the domain gap. Existing reconstruction-based methods often rely on frozen pre-trained encoders, restricting adaptation to domain-specific patterns and degrading localization accuracy. Meanwhile, prototype-based learning offers interpretable representations but commonly suffers from prototype collapse, where a few prototypes dominate training and reduce diversity. To address these issues, we propose DNP-ConFormer, a unified framework that integrates a trainable encoder with prototype-guided reconstruction and a Diversity-Aware Alignment Loss. A momentum encoder enables stable domain-adaptive representation learning, while a lightweight Prototype Extractor discovers informative normal prototypes and injects them into the decoder via attention to guide reconstruction. The proposed alignment objective further encourages balanced feature-to-prototype assignments, effectively mitigating prototype collapse. Extensive experiments on multiple medical imaging benchmarks demonstrate improved representation quality and anomaly localization compared with prior methods. Visualization and prototype assignment analyses further validate the effectiveness and interpretability of our approach. The code is available at https://github.com/liluhu0/DNP-ConFormer.

Detecting fraudulent credit card transactions remains a significant challenge, due to the extreme class imbalance in real-world data and the often subtle patterns that separate fraud from legitimate activity. Existing research commonly attempts to address this by generating synthetic samples for the minority class using approaches such as GANs, VAEs (Variational Autoencoders), or hybrid generative models. However, these techniques, particularly when applied only to minority-class data, tend to result in overconfident classifiers and poor latent cluster separation, ultimately limiting real-world detection performance. In this study, we propose the Causal Prototype Attention Classifier (CPAC), an interpretable architecture that promotes class-aware clustering and improved latent space structure through prototype-based attention mechanisms and we couple it with the encoder of a Variational Autoencoder-Generative Adversarial Network (VAE-GAN) in order to achieve improved latent cluster separation moving beyond post-hoc sample augmentation. We compared CPAC-augmented models to traditional oversamplers, such as SMOTE, as well as to state-of-the-art generative models, both with and without CPAC-based latent classifiers. Our results show that classifier-guided latent shaping with CPAC delivers superior performance, achieving an F1-score of 93.74% and recall of 92.85%, along with improved latent cluster separation. Further ablation studies and visualizations provide deeper insight into the benefits and limitations of classifier-driven representation learning for fraud detection. The codebase for this work can be found at the following link: https://github.com/claudiunderthehood/VAEGAN-CPAC.git.