Dual-Domain Equivariant Generative Adversarial Network

Brain tumor segmentation remains difficult because enhancing tumor (ET) has low contrast and overlaps surrounding tissue, while scanner and site variation causes domain shift. We propose DE-GAN, a contrast-enhancing conditional GAN that combines input-adaptive dynamic convolutions, style-aware feature mixing, and coordinate encoding to synthesize slice-adaptive FLAIR images. A label-guided, class-conditional target separates tumor-core (TC) and ET intensities while preserving anatomy. The generated FLAIR is concatenated with the original MR modalities and used to train a 3D U-Net. Across BraTS 2015, 2018, and 2019, DE-GAN improves segmentation over the baseline and static EnhGAN replacement on most reported TC/ET metrics, with the largest gains from retaining both original and enhanced FLAIR. Code and pretrained models are available at https://github.com/zkhansuri-ui/DE-GAN.

A vocoder is a pivotal component of modern text-to-speech (TTS) systems. Despite the significant progress of neural network-based vocoders, accurate phase reconstruction remains the main challenge limiting both audio quality and modeling efficiency. We introduce PhaseGAN, a lightweight vocoder that addresses this limitation through a "mel $\rightarrow$ Amplitude $\rightarrow$ Phase" reconstruction pipeline. By reconstructing amplitude and phase spectra via distinct methodologies, the proposed PhaseGAN outperforms state-of-the-art baselines while utilizing fewer model parameters and reduced computational requirements. The compact version generates high-fidelity audio with approximately 500K parameters and 1 GMAC computational load, making it highly suitable for real-time applications on edge devices. In addition, our approach exhibits exceptional musical audio synthesis capabilities despite no training on musical data, illustrating unprecedented cross-domain generalization. See https://github.com/phasegan/phasegan-audio-demo for demos of our work.

In a federated learning setup for GANs, several adversarial attacks are possible. One such attack is label flipping, in which malicious clients deliberately alter label information during local training in order to manipulate the global generator. The objective of this attack is to skew the learned generation distribution so that samples conditioned on a target label are instead mapped to a source class. In this work, we investigate the effectiveness of label flipping attacks in federated GANs through both theoretical analysis and empirical evaluation. We further consider an oversampling based variant, in which malicious clients upweight poisoned samples during local training to amplify their influence on the aggregated global model. We quantify the resulting distributional shift by computing the Kullback Leibler divergence between the clean and poisoned class conditional distributions, and show both analytically and on FEMNIST, MNIST, and CIFAR10 that the semantic damage of the attack grows linearly in the effective poisoning strength while deviation from the true target distribution grows only quadratically, making the attack effective yet difficult to detect from label agnostic metrics.

The emergence of medical deepfakes, i.e., medical images manipulated by deep generative models, poses a significant threat to clinical workflows. However, existing detectors suffer from two critical limitations: poor generalization to unseen generative architectures for manipulation detection and lack of interpretability. In this context, we present HexMIL (Hierarchical EXplainable Multiple Instance Learning), a mask-free medical deepfake detector that simultaneously addresses both limitations using only binary volume-level supervision. HexMIL decomposes each CT volume into a two-level hierarchy of patches and slices, aggregated via independent Gated Attention modules whose weights are directly combined into a full-resolution 3D attention volume that localizes the manipulated sub-region without any pixel-level annotation. Unlike post-hoc methods such as Grad-CAM, HexMIL's attention weights constitute the exact forward computation driving the classification decision, providing ante-hoc and structurally faithful spatial attribution. We evaluate HexMIL on M3DSynth and CT-GAN datasets under a rigorous cross-generator generalization protocol, training on a single generative architecture and testing on unseen ones. HexMIL outperforms all baselines by $+9.1$ AUC and $+9.4$ F1 in out-of-domain classification, and achieves the best average IoU and Pointing Game score in localization. Project page: opontorno.github.io/hexmil.

Generative models learn the statistical properties of their training data, so high-quality generation depends on clean and representative datasets. In scientific imaging, acquisition often yields noisy measurements, while collecting clean references can be costly, impractical or even unattainable. Training directly on these measurements results in a model that reproduces the corrupted data. This can be circumvented by learning the clean population distribution directly from the noisy data. Conditional flow matching (CFM) combines a simple regression objective with stable training, efficient sampling, and strong image-generation performance, making it a natural framework for this setting. We introduce Noise-Robust Conditional Flow Matching (NR-CFM), an unconditional generator that learns from one corrupted observation per image. NR-CFM provides a closed-form clean endpoint correction for additive white Gaussian noise and learns a data-driven correction for general Gaussian corruptions with more complex covariance structure. Across the evaluated corruption settings, NR-CFM outperforms NR-GAN in most cases and remains competitive with Ambient Diffusion in the high-noise regime. We further evaluate NR-CFM on scientific data at signal-to-noise ratios as low as $0.001$, where it generates plausible particle images from severely corrupted measurements.

Validating Explainable Artificial Intelligence (XAI) methods in medical imaging requires ground-truth data with known locations of informative features. However, current approaches rely on expert annotations, which are prone to labeling errors, or on hand-crafted artificial perturbations superimposed onto healthy images to mimic lesions or malignant features, which lack clinical realism. We present Local Label-Informed Feature Transfer (LLIFT), a framework for generating semi-synthetic brain magnetic resonance images with realistic lesions placed in user-controlled regions, which does not require pixel-level lesion annotations during training. We implement LLIFT with two generative paradigms: LLIFT-GAN, a custom GAN that learns pathological features from binary class labels alone, and LLIFT-DM, a diffusion-based inpainting pipeline conditioned on bounding-box masks via ControlNet. Both approaches are evaluated on brain magnetic resonance imaging data derived from the Human Connectome Project. In evaluations, both achieve Fréchet Inception Distance scores, with respect to the real pathological distribution, that are comparable to the inter-class reference between healthy and pathological images in the given dataset. Furthermore, qualitative inspection confirms the realism of lesion structures. The resulting benchmark datasets provide spatially controlled ground truth data for evaluating XAI methods in medical imaging.

Semi-supervised generative adversarial networks (SSL-GANs) can exploit large unlabeled datasets while retaining a classifier in the discriminator, but their training is often unstable. This paper proposes a population-based evolutionary training strategy in which discriminator learning is formulated as a multi-objective optimization problem. Instead of aggregating the supervised and unsupervised components of the SSL objective into a single scalar loss, the method maintains a population of discriminators ranked by Pareto dominance, enabling the exploration of different trade-offs between classification accuracy and real/fake discrimination. This formulation aims to improve both roles of SSL-GANs: learning accurate classifiers and training generators capable of producing realistic samples. We analyze several variants, including an elitist strategy and a mono-objective ablation, to assess the role of multi-objective selection. Experiments on MNIST with limited labels show improved training robustness compared to SSL-GAN and CE-SSL-GAN state-of-the-art baselines, while the elitist variant consistently achieves the highest classification accuracy.

The generation of synthetic relational databases often involves modeling complex temporal dynamics, such as transaction logs or event sequences. A significant challenge in this domain is the handling of categorical time series (e.g., status codes), where standard encoding methods like one-hot encoding fail to capture intrinsic frequency-domain features such as seasonality and cyclicity. In this paper, we introduce Sequential RC-TGAN (Seq. RC-TGAN), a temporal extension of the RC-TGAN framework, equipped with a novel integrated loss function based on the \textit{Spectral Envelope Theory}. This differentiable loss allows the generator to directly optimize the preservation of latent periodic structures via backpropagation. While spectral envelope theory is inherently designed for categorical sequences, we extend this frequency-domain regularization to continuous time series by employing a Variational Gaussian Mixture Model (VGM) discretization strategy. To establish a mathematically rigorous evaluation standard, we simulate categorical time series governed by a parameter $α$, with exactly known theoretical spectral envelopes. Integrating these dynamic sequences into the child tables of a relational database yields a robust ground-truth benchmark for evaluating the frequency-domain fidelity of our generative framework. Furthermore, we address the lack of robust evaluation standards for relational time series by proposing two new metrics: Spectral Density Divergence and Spectral Envelope Divergence. Experimental results on real-world datasets, as well as our simulated benchmarks, demonstrate that our end-to-end approach significantly outperforms state-of-the-art systems in reproducing cyclic patterns and long-term seasonality across both categorical and continuous features.

Neural Architecture Search (NAS) has emerged as a pivotal technique in optimizing the design of Generative Adversarial Networks (GANs), automating the search for effective architectures while addressing the challenges inherent in manual design. This paper provides a comprehensive review of NAS methods applied to GANs, categorizing and comparing various approaches based on criteria such as search strategies, evaluation metrics, and performance outcomes. The review highlights the benefits of NAS in improving GAN performance, stability, and efficiency, while also identifying limitations and areas for future research. Key findings include the superiority of evolutionary algorithms and gradient-based methods in certain contexts, the importance of robust evaluation metrics beyond traditional scores like Inception Score (IS) and Fréchet Inception Distance (FID), and the need for diverse datasets in assessing GAN performance. By presenting a structured comparison of existing NAS-GAN techniques, this paper aims to guide researchers in developing more effective NAS methods and advancing the field of GANs.

Early detection of aphid infestation in crops is essential for preventing yield loss and reducing unnecessary pesticide use. Hyperspectral imaging combined with Spectral Information Divergence (SID) analysis offers a non-destructive approach for monitoring plant health; however, deep learning methods applied to hyperspectral data are often limited by small dataset sizes. In this study, a data-efficient generative adversarial network (FastGAN) was employed to augment a hyperspectral SID dataset of faba bean leaves containing healthy and aphid-infested samples. The trained generator produced 10,000 synthetic images preserving structural and spectral characteristics of real samples. Image quality was evaluated using Frechet Inception Distance (FID), demonstrating stable convergence and realistic reconstruction of leaf morphology and infestation patterns. The augmented dataset was used to train four classification architectures: VGG16, ResNet-50, EfficientNet, and Vision Transformer (ViT). Results showed that dataset augmentation significantly improved classification robustness, with performance progressively increasing from classical convolutional networks to transformer-based models. The ViT model achieved the highest accuracy and F1-scores, while EfficientNet provided strong balanced performance and ResNet-50 showed moderate improvements over VGG16. Confusion matrix analysis confirmed reduced false negatives and improved disease detection when using advanced architectures. The findings demonstrate that FastGAN-based augmentation effectively enhances hyperspectral plant disease classification and that transformer-based models provide the most reliable discrimination between healthy and infested leaves.

We present a Dual-Domain Equivariant Generative Adversarial Network (DDE-GAN) for multimodal CT-PET image synthesis. Traditional GAN-based approaches often operate solely in the spatial domain and ignore geometric consistency, resulting in limited structural fidelity. DDE-GAN addresses these challenges by jointly learning from both spatial and frequency (Fourier) domains, capturing complementary anatomical and spectral information. Furthermore, rotational equivariance embedded in the physics of the CT and PET measurements are integrated into the loss of both the generator and discriminator to ensure consistent responses under rotations, improving anatomical accuracy. A hierarchical dual-domain training strategy enforces intra- and inter-domain consistency through multi-stage loss functions. Evaluated on the HECKTOR 2022 CT-PET dataset, DDE-GAN achieves superior synthesis quality over baseline models for CT-PET image synthesis. The results demonstrate that combining dual-domain learning with geometric equivariance substantially enhances multimodal image synthesis accuracy and robustness, enabling practical applications in PET completion and data augmentation.

Multi-modal MRI brain image translation via available modalities holds significant practical importance in modern medicine, providing robust support for early diagnosis, treatment planning, and outcome assessment of diseases. For this purpose, it is important to ensure the fidelity of the tumor regions after translation. However, existing brain image translation methods ignore the structure information of different tumor regions, which could assist translation models in enhancing the quality and clinical applicability of the translated images. In this work, we propose a novel translation model called HTSCGAN, which is a unified multi-modal brain image translation generative adversarial model integrating the structural information within tumor regions with the aim of improving the quality of brain image translation. Specifically, the generator employs three Patch Contrast Module (PCM) with different patch sizes to capture the hierarchical structural information of the tumor regions. In addition, a pretrained Patch Classifier (PC) and a pretrained Structure-Aware Encoder (SAE) are employed to derive the generated image containing the same tumor region structure as the ground truth image via patch classification loss and tumor perceptual loss, respectively. The experiments on BraTS2020 and BraTS2021 demonstrate strong performance of our model in both translation tasks and down stream segmentation tasks, highlighting its effectiveness in enhancing the quality and clinical relevance of the translated brain images. Our code is available at https://anonymous.4open.science/r/HTSCGAN.

Blind face restoration on consumer devices has to balance image quality against speed and memory. Strong methods such as GFPGAN and CodeFormer give good perceptual quality, but they rely on large pretrained generative priors and on operators such as attention, codebook lookup, and style modulation that are hard to compile and quantize on the small neural processing units (NPUs) used in consumer hardware. Small convolutional restorers run fast enough, but they tend to over-smooth and to leave artifacts around the eyes, nose, and mouth. We present CFRNet, a 2.0,M-parameter ResNet-style restorer for on-device use at $256\times256$, the common face-crop size on consumer NPUs. The main idea is Cycle-Consistent Fixed-Point Training (CCFP). Instead of training the network for one pass and then running it several times by hand, we train it to act as a fixed-point operator, so that applying it again to a restored face does not change the face. CCFP uses three training losses, namely progressive multi-cycle supervision, an idempotence loss, and a re-degradation cycle loss, and it adds no cost at inference. To compare fairly under our deployment limits, we retrain all baselines from scratch at the same $256\times256$ resolution. On a 300-image test set, CFRNet reaches the best perceptual score (LPIPS 0.250 at three cycles, which is 31% lower than one cycle) and also the best PSNR and SSIM at two cycles. It runs in about 23,ms per cycle in INT8 on a HiSilicon Hi3402 NPU, while the same baselines cannot be compiled to that chip. The cycle count $k$ acts as a simple quality knob that needs no retraining: PSNR is best at $k\!=\!2$ and LPIPS keeps improving up to $k\!=\!3$. We further show that the same idea works with a plain CNN that is even easier to deploy, and we run the model in real time on an in-car driver-monitoring board.

Conventional Generative Adversarial Networks (GANs) for Single Image Super-Resolution (SISR) often struggle with hallucinated artifacts, largely because standard discriminators evaluate overall image naturalness rather than strict conditional realism. To address this, we propose MaCo-GAN, a novel manifold-contrastive GAN framework that replaces the conventional adversarial loss with a supervised contrastive objective. A core component of our method is a dynamic fake sample synthesizer that transforms ground truth (GT) data into a spectrum of challenging, perceptually plausible fake images that strictly maintain low-resolution (LR) correspondence. Utilizing these synthesized samples, we establish a robust contrastive minimax game: the generator is trained to attract its predictions toward on-manifold fakes (low distortion) and repel them from off-manifold fakes (high distortion), while the discriminator optimizes the exact opposite. By simply replacing the adversarial loss of a baseline SR model with our proposed objective, we demonstrate consistent improvements in the perception-distortion trade-off across various benchmarks. Extensive ablation studies validate the effectiveness of our framework and provide deep insights into the dynamics of this conditional contrastive game.

We introduce IRIS-GAN, a specialist forensic detector for synthetic face images under cross-generator shift. Rather than addressing universal synthetic-image detection, we focus on faces generated by generative adversarial networks (GANs), which are state-of-the-art in deepfake content, and train the detector through staged exposure to increasingly demanding GAN families while retaining earlier generators. The final model reaches fake-detection rates above 99% across the GAN families considered and classifies an external real-face dataset with 98.9% accuracy. Grad-CAM analysis further reveals measurable generator-dependent spatial response patterns, which remain informative for a secondary heatmap-only classifier. Out-of-family tests on diffusion-generated faces confirm that IRIS-GAN is a specialist detector, with some capability to reach non-GAN deepfakes. These results establish staged training as an effective strategy for robust GAN-face forensics.

Generating high-fidelity synthetic tabular data under formal differential privacy guarantees remains an open challenge. Methods that provide strong theoretical protection typically sacrifice the modeling of inter-feature dependencies required for realistic synthesis, while architectures that excel at capturing complex column relationships offer only empirical privacy guarantees. We present PATE-TabTransGAN, a generative framework that integrates the Private Aggregation of Teacher Ensembles (PATE) mechanism with a Transformer-based student discriminator to jointly address both requirements, and employs a GNMax RDP accountant for numerically stable privacy accounting. An ensemble of Logistic Regression teachers trained on disjoint partitions supervise the student via noisy-aggregated labels, and a residual generator is optimized against this differentially private student, inheriting formal (ε, δ)-DP guarantees by post-processing. PATE-TabTransGAN was compared with PATE-GAN, DP-GAN, and DP-CTGAN, considered state-of-the-art in differentially private tabular synthesis. Experiments conducted on four tabular benchmarks (Adult, Breast, Cardio, Cervical) confirmed the high quality of the proposed method: PATE-TabTransGAN attains the best or tied-best AUROC on all four datasets. On AUCPR it matches the strongest baseline on Cardio, leads on Cervical, and trails on Breast; on Adult, we demonstrate that AUCPR is highly sensitive to positive-class convention, and that the observed gap is consistent with a convention difference between evaluation pipelines rather than a synthesis deficit.

Accurate carbon emission monitoring is critical for climate policy and emerging regulatory mechanisms such as the EU Carbon Border Adjustment Mechanism, yet city-level high-frequency monitoring data remain extremely scarce, severely limiting data-hungry deep learning models. Time series generation is a natural remedy, but existing GAN and diffusion-based generators often provide limited explicit supervision for the domain structure of carbon emission data: they may match marginal distributional statistics while insufficiently preserving cross-variable correlations between CO$_2$ and co-emitted pollutants and meteorological factors, and tend to collapse the first-difference statistics of atmospheric measurements, producing sequences that are smooth on average but lack the realistic step-wise variability of the underlying signals. We propose TriHead-GAN, a Transformer-based adversarial framework whose triple-head discriminator jointly supervises three complementary aspects of the joint distribution: distributional authenticity via a Wasserstein critic, cross-variable dependency via leakage-free regression of the target variable, and step-wise temporal smoothness via adjacent-difference prediction. The generator combines global self-attention with local temporal convolution, per-step noise injection, and an anti-smoothing loss that matches first-difference statistics. Experiments on the self-collected Changsha Carbon dataset, two public carbon datasets (China, US), and the ETTh1 benchmark show that TriHead-GAN achieves favorable performance over mainstream baselines on the vast majority of settings, and that the resulting synthetic windows improve downstream forecasting accuracy in low-resource carbon monitoring scenarios.

Conditional generative adversarial networks (cGANs) have enabled high-fidelity computational staining and destaining of hematoxylin and eosin (H&E) in digital pathology whole-slide images (WSI). However, their ability to generalize to out-of-distribution WSI across institutions without retraining remains insufficiently characterized. Previously developed cGAN models trained on 102 registered prostate core biopsy WSIs from Brigham and Women's Hospital were evaluated on 82 spatially unregistered WSIs acquired at Stanford University. To mitigate domain shift without retraining, a preprocessing pipeline consisting of histogram-based stain normalization for H&E-stained WSIs and channel-wise intensity calibration for unstained WSIs was developed. Because image registration was intentionally omitted for real-world deployment conditions, the reported quantitative results are conservative lower bounds reflecting both model performance and limited spatial alignment. Under these conditions, virtual destaining achieved a Pearson correlation coefficient (PCC) of 0.854, structural similarity index measure (SSIM) of 0.699, and peak signal-to-noise ratio (PSNR) of 18.41 dB. H&E restaining from computationally destained outputs outperformed direct staining from ground-truth unstained inputs across all metrics (PCC: 0.798 vs. 0.715; SSIM: 0.756 vs. 0.718; PSNR: 20.08 vs. 18.51 dB), suggesting that preprocessing quality may be more limiting than model capacity. Qualitative pathological review indicated preservation of benign glandular structures while showing that malignant glands were often rendered with vessel-like morphologies. These findings support the feasibility of applying cGAN-based computational H&E staining and destaining generative models to external WSI datasets using preprocessing-based adaptation alone while defining specific morphological targets for future domain adaptation.

We establish the first population risk bounds for Kolmogorov-Arnold Networks (KANs) trained by mini-batch SGD with gradient clipping, covering non-private SGD as well as differentially private SGD (DP-SGD) with Gaussian perturbations that interpolate between independent and temporally correlated noise. This setting is substantially closer to practice than prior KAN theory along two axes: training is by mini-batch SGD, the standard recipe for modern networks, rather than full-batch gradient descent (GD); and correlated-noise mechanisms have empirically shown a more favorable privacy-utility tradeoff than independent-noise mechanisms. Our results cover the corresponding full-batch GD and independent-noise DP-GD results for KANs by Wang et al. (2026), while yielding sharper fixed-second-layer specializations. The technical core is a new analysis route for correlated-noise DP training in the non-convex regime. Temporal dependence breaks the conditional-centering structure underlying standard one-step SGD arguments, and the projection step obstructs the exact cancellation structure of correlated perturbations. We address these difficulties through an auxiliary unprojected dynamics, a shifted iterate that absorbs the current noise perturbation, and a high-probability bootstrap certifying projection inactivity. Combining this optimization analysis with a stability-based generalization argument yields the stated population risk bounds. To the best of our knowledge, this is the first optimization and population risk analysis of a correlated-noise mechanism for DP training beyond convex learning, in particular for neural networks.

In modern GANs, maintaining an Exponential Moving Average (EMA) of the generator's weights is a standard practice, as such an averaged model consistently outperforms the actively trained generator. However, the EMA generator is used for final deployment only and does not influence the training process. To address this missed opportunity, we introduce Self-Distilled GAN (SD-GAN) that employs the EMA generator as a teacher to guide the active generator (student) via perceptual loss. We prove the local asymptotic stability of SD-GAN in the Dirac-GAN setting and show that it dampens the parasitic cycling behavior that plagues the conventional GANs. Empirical evaluations across established architectures and datasets demonstrate that SD-GAN improves the final image quality on several metrics (FID and random-FID in particular), stabilizes the optimization trajectory and provides additional learning guidance that is not trivially correlated with the conventional adversarial loss. It also proves effective for fine-tuning pretrained GAN models.

Purpose: We aim to enhance the image quality of point-of-care ultrasound (POCUS) devices using deep learning and a novel paired dataset of POCUS and high-end ultrasound images. Approach: We collected the first accurately paired dataset using a custom-built automated gantry system of low-end POCUS and high-end ultrasound images. A conditional generative adversarial network (cGAN) was utilized based on the pix2pix architecture, with a U-Net generator that incorporates both L1 and structural similarity index (SSIM) losses to improve perceptual quality. Pretraining on a simulation dataset further boosts performance. Evaluation was performed on 1064 paired ex vivo tissue and phantom ultrasound image sets. Results: Our approach improves the SSIM from 0.29 to 0.54 and PSNR from 19.16 dB to 22.41 dB. No-reference metrics also indicate substantial enhancement, with the Natural Image Quality Evaluator (NIQE) and Perception-based Image Quality Evaluator (PIQE) scores dropping from 7.95 to 4.44 and 31.12 to 19.99, respectively. Conclusions: This work presents the first publicly available accurately paired dataset of low-end POCUS to high end ultrasound images. Additionally, our results demonstrate the potential of the proposed framework to overcome hardware limitations of handheld POCUS, enhancing its diagnostic value in low-resource and point-of-care settings. The POCUS-IQ Dataset is publicly available at https://github.com/NKI-MedTech-AI/POCUS-IQ.

In this paper, we propose MelShield, a robust, in-generation, keyed audio watermarking framework that embeds identifiable signals into AI-generated audio for copyright protection and reliable attribution. Specifically, MelShield operates in the Mel-spectrogram domain during the generation process, targeting intermediate acoustic representations in Mel-conditioned pipelines for text-to-speech (TTS) generation. The core idea is to treat the intermediate Mel-spectrogram as the host signal and embed a short binary payload via low-energy, keyed spread-spectrum perturbations distributed across carefully selected time-frequency regions prior to waveform synthesis. By performing watermarking before vocoder inference, MelShield remains plug-and-play for Mel-conditioned TTS architectures and does not require modification or retraining of the underlying TTS generation vocoder, such as DiffWave and HiFi-GAN. Moreover, the multi-user keyed construction enables scalable user-specific attribution, while the keyed verification mechanism limits unauthorized decoding, thereby reducing the risk of large-scale extractor probing and adversarial analysis. Extensive experiments on DiffWave and HiFi-GAN demonstrate that MelShield achieves reliable watermark extraction, approaching 100% bit accuracy, even under signal distortions, e.g., compression and additive noise, while preserving high perceptual audio quality.

With the development of deep learning, medical image processing has been widely used to assist clinical research. This paper focuses on the denoising problem of low-dose computed tomography using deep learning. Although low-dose computed tomography reduces radiation exposure to patients, it also introduces more noise, which may interfere with visual interpretation by physicians and affect diagnostic results. To address this problem, inspired by Cycle-GAN for unsupervised learning, this paper proposes an end-to-end unsupervised low-dose computed tomography denoising framework. The proposed framework combines a U-Net structure for multi-scale feature extraction, an attention mechanism for feature fusion, and a residual network for feature transformation. It also introduces perceptual loss to improve the network for the characteristics of medical images. In addition, we construct a real low-dose computed tomography dataset and design a large number of comparative experiments to validate the proposed method, using both image-based evaluation metrics and medical evaluation criteria. Compared with classical methods, the main advantage of this paper is that it addresses the limitation that real clinical data cannot be directly used for supervised learning, while still achieving excellent performance. The experimental results are also professionally evaluated by imaging physicians and meet clinical needs.

Facial attribute editing aims to modify target attributes while preserving attribute-irrelevant content and overall image fidelity. Existing GAN-based methods provide favorable controllability, but often suffer from weak alignment between style codes and attribute semantics. Diffusion-based methods can synthesize highly realistic images; however, their editing precision is limited by the entanglement of semantic directions among different attributes. In this paper, we propose AttDiff-GAN, a hybrid framework that combines GAN-based attribute manipulation with diffusion-based image generation. A key challenge in such integration lies in the inconsistency between one-step adversarial learning and multi-step diffusion denoising, which makes effective optimization difficult. To address this issue, we decouple attribute editing from image synthesis by introducing a feature-level adversarial learning scheme to learn explicit attribute manipulation, and then using the manipulated features to guide the diffusion process for image generation, while also removing the reliance on semantic direction-based editing. Moreover, we enhance style-attribute alignment by introducing PriorMapper, which incorporates facial priors into style generation, and RefineExtractor, which captures global semantic relationships through a Transformer for more precise style extraction. Experimental results on CelebA-HQ show that the proposed method achieves more accurate facial attribute editing and better preservation of non-target attributes than state-of-the-art methods in both qualitative and quantitative evaluations.

A key challenge in segmentation in digital histopathology is inter- and intra-stain variations as it reduces model performance. Labelling each stain is expensive and time-consuming so methods using stain transfer via CycleGAN, have been developed for training multi-stain segmentation models using labels from a single stain. Nevertheless, CycleGAN tends to introduce noise during translation because of the one-to-many nature of some stain pairs, which conflicts with its cycle consistency loss. To address this, we propose the Domain Shift Aware CycleGAN, which reduces the presence of such noise. Furthermore, we evaluate several advances from the field of machine learning aimed at resolving similar problems and compare their effectiveness against DSA-CycleGAN in the context of multi-stain glomeruli segmentation. Experiments demonstrate that DSA-CycleGAN not only improves segmentation performance in glomeruli segmentation but also outperforms other methods in reducing noise. This is particularly evident when translating between biologically distinct stains. The code is publicly available at https://github.com/zeeshannisar/DSA-CycleGAN.

Obtaining truly representative pore-scale images that match bulk formation properties remains a fundamental challenge in subsurface characterization, as natural spatial heterogeneity causes extracted sub-images to deviate significantly from core-measured values. This challenge is compounded by data scarcity, where physical samples are only available at sparse well locations. This study presents a multi-conditional Generative Adversarial Network (cGAN) framework that generates representative pore-scale images with precisely controlled properties. The framework was trained on thin section samples from four depths (1879.50-1943.50 m) of a carbonate formation, simultaneously conditioning on porosity and depth within a single model. It processes RGB thin section images that preserve critical mineralogical information (anhydrite-dolomite differentiation, grain boundaries, porosity distinctions) lost in conventional grayscale representations, capturing characteristics from grainstone fabrics to crystalline textures with anhydrite inclusions. The model achieved strong porosity control (R^2 = 0.95) across all formations with mean absolute errors of 0.0099-0.0197. Morphological validation confirmed preservation of average pore radius, specific surface area, and tortuosity within acceptable tolerances. Two-point correlation (S2) analysis confirmed that generated images preserve the spatial continuity and characteristic length scales of natural pore networks, with results consistent across the imaging resolutions tested (1.8-3.0 micron/pixel). Validated against core sample properties, generated images showed higher property fidelity with dual-constraint errors of 1.9-12.4% compared to 37.5-713.6% for randomly extracted real sub-images. This capability provides practical tools for subsurface characterization, particularly valuable for carbon storage, geothermal energy, and groundwater management.

Recent advances in continuous conditional generative modeling, including Continuous conditional Generative Adversarial Network (CcGAN) and Continuous Conditional Diffusion Model (CCDM), estimate high-dimensional data distributions conditioned on scalar regression labels such as angles, ages, or temperatures. However, fixed-size vicinal training in CcGAN can be sensitive to non-uniform label densities, whereas CCDM relies on computationally expensive iterative sampling. To address these issues, we propose CcGAN-AVAR, an imbalance-aware extension of CcGAN that combines soft/hybrid adaptive vicinity with auxiliary discriminator-guided regularization. The adaptive vicinity constructs a label-dependent local radius according to the available samples around each target condition, and the multi-task discriminator supplies both a regression signal for label consistency and a density-ratio-estimation signal for distribution matching. We further provide a theoretical interpretation characterizing how adaptive vicinal weighting affects the local bias-variance behavior of the discriminator target, how hybrid truncation reduces objective-level cross-condition mixing, and how the density-ratio-based generator penalty approximates a Pearson Chi-square discrepancy up to the estimation error of the density-ratio branch. Extensive experiments on four datasets, including the newly constructed imbalanced RC-49-I, covering resolutions from 64x64 to 256x256 across eleven settings, demonstrate that CcGAN-AVAR obtains strong generation quality and label consistency while preserving the one-step sampling efficiency of GANs, achieving 300x--2000x faster inference than CCDM.

The tabular form constitutes the standard way of representing data in relational database systems and spreadsheets. But, similarly to other forms, tabular data suffers from class imbalance, a problem that causes serious performance degradation in a wide variety of machine learning tasks. One of the most effective solutions dictates the usage of Generative Adversarial Networks (GANs) in order to synthesize artificial data instances for the under-represented classes. Despite their good performance, most of the proposed GAN models do not take into account the vector subspaces of the input samples in the real data space, leading to data generation in arbitrary locations. In addition, the class labels are handled in the same manner as the other categorical variables, so conditional sampling by class is rendered less effective. To overcome these problems, this study presents ctdGAN, a conditional GAN for alleviating class imbalance in tabular datasets. Initially, ctdGAN executes a space partitioning step to assign cluster labels to the input samples. Subsequently, it utilizes these labels to synthesize samples via a novel probabilistic sampling strategy and a new loss function that penalizes both cluster and class mis-predictions. In this way, ctdGAN generates samples in subspaces that resemble those of the original data distribution. We also introduce several other improvements, including a simple, yet effective cluster-wise scaling technique that captures multiple feature modes without affecting data dimensionality. The evaluation of ctdGAN with 14 imbalanced datasets demonstrated its strong ability in generating high fidelity samples and improving classification accuracy.

We present a novel machine-learning (ML) approach (EM-GANSim) for real-time electromagnetic (EM) propagation that is used for wireless communication simulation in 3D indoor environments. Our approach uses a modified conditional Generative Adversarial Network (GAN) that incorporates encoded geometry and transmitter location while adhering to the electromagnetic propagation theory. The overall physically-inspired learning is able to predict the power distribution in 3D scenes, which is represented using heatmaps. We evaluated our method on 15 complex 3D indoor environments, with 4 additional scenarios later included in the results, showcasing the generalizability of the model across diverse conditions. Our overall accuracy is comparable to ray tracing-based EM simulation, as evidenced by lower mean squared error values. Furthermore, our GAN-based method drastically reduces the computation time, achieving a 5X speedup on complex benchmarks. In practice, it can compute the signal strength in a few milliseconds on any location in 3D indoor environments. We also present a large dataset of 3D models and EM ray tracing-simulated heatmaps. To the best of our knowledge, EM-GANSim is the first real-time algorithm for EM simulation in complex 3D indoor environments. We plan to release the code and the dataset.