Multimodal Contrastive Learning

Robust self-supervised learning of multi-modal video representations is critical for real-world applications such as driver distraction detection, where multiple sensors provide complementary but noisy signals. Conventional contrastive objectives, such as InfoNCE, assume all negatives are equally informative and all positives are reliable. However, this assumption is frequently violated in multi-modal data due to viewpoint changes, occlusions, or semantic overlap across modalities. In this work, we propose a novel framework for multi-modal global alignment that addresses these challenges by jointly modeling faulty negatives and unreliable or faulty positives. We introduce soft targets derived from cycle-consistency scores to relax the hard-negative assumption, and a weighting mechanism based on similarity distributions to mitigate the impact of noisy or faulty positives. Our approach extends traditional pairwise alignment to a principled global multi-modal setting, aggregating alignment information across all modality pairs. We evaluate our method on the Drive&Act dataset, demonstrating that it consistently outperforms both pairwise and existing global alignment baselines across RGB, IR, Depth, and Skeleton modalities. Cross-view ablation studies further show strong generalization to unseen camera perspectives, highlighting the robustness of our representations. Overall, our framework provides a scalable and effective solution for self-supervised global multi-modal representation learning, enabling reliable driver distraction detection and pioneering in real-world multi-modal video understanding. Our code will be published on GitHub.

Multimodal data fusion involves integrating and analyzing information from multiple modalities to uncover latent correlations and complementary patterns, thereby enhancing data processing and decision-making. While existing methods for structured multimodal inputs are typically designed around specific tasks and assume fully observed modalities, real-world applications often suffer from uncertain or missing modality inputs due to various factors. Some traditional models overly emphasize local interactions within missing modalities, neglecting the global complementary cues embedded in multimodal representations. To overcome these limitations, we propose a Dynamic Multimodal Data Fusion model based on Contrastive Learning (CL-DMDF). CL-DMDF introduces a novel attention mechanism that operates across both feature and modality dimensions to compute reliable attention scores, effectively reflecting importance at each level. The CL-DMDF further incorporates an entity-centroid contrastive learning module that constructs centroid-based positive samples from entity features to enhance discriminative learning. Additionally, an adaptive fusion module is employed to improve the efficiency and accuracy of dynamic fusion strategies. Extensive experiments conducted on three datasets demonstrate the effectiveness of the CL-DMDF across diverse multimodal fusion tasks.

Open-set 3D recognition requires models that generalize to rare or unseen categories. Recent approaches address this by distilling language-vision knowledge into 3D encoders, typically relying on heavy 2D ViTs and aligning each point cloud with a single image or caption, thus anchoring representations to partial views. We propose aligning each point cloud with multiple images and textual descriptions to capture a more holistic understanding of 3D objects. To realize this idea, it is essential to design a loss function capable of jointly aligning a 3D instance with multiple matched signals, multi-view images and multiple texts, while separating positive aggregation from negative competition. We introduce such a function, termed the decoupled multi-positive contrastive loss. Our formulation enhances the loss's hardness-aware focus on challenging negatives, avoiding the "spotlight crowding" that occurs when many positives share the same softmax with all the negatives. Complementing this, we present a lightweight text adapter applied only to web captions, reducing the domain gap to curated annotations and enabling effective use of large-scale unsupervised text. Our model demonstrates state-of-the-art open-vocabulary performance on long-tail benchmarks, yielding substantial zero-shot improvements while sustaining high frame rates.

Accurate prediction of drug-target interactions (DTI) is critical for drug discovery. Existing methods often rely on single-modal representations (e.g., sequences or graphs) or combine only two modalities, overlooking 3D structural features. To address this challenge, we propose TriMod-DTI, a triple-modal contrastive learning framework that incorporates 1D sequences, 2D graphs, and 3D structures of drugs and proteins, obtaining the universal and complementary feature representations for DTI prediction. We design a Feature Extractor to capture drug and target features across the three modalities, thereby enriching their representations. We further propose a triple-modal contrastive learning strategy to align different modal representations of the same drug or protein in the latent space. By constructing cross-modal positive and negative sample pairs, this approach enhances the model's discriminative ability. Experiments on three benchmark datasets demonstrate that TriMod-DTI outperforms state-of-the-art methods. The ablation studies validate the contributions of each modality. Moreover, case studies highlight its practical potential for DTI prediction and drug discovery.

Contrastive learning is effective for aligning paired views or modalities, but alignment beyond two modalities remains non-trivial and comparatively underexplored. Pairwise CLIP-style losses decompose multi-modal alignment into independent two-way comparisons and therefore do not explicitly model higher-order dependencies among multiple modalities. Recent beyond-pairwise objectives approach this problem from statistical or geometric perspectives, but arbitrary-modality alignment still lacks a principled criterion for defining what each modality should preserve and compress relative to the others. We revisit arbitrary-modality alignment through the Information Bottleneck principle. In multi-modal learning, sufficiency should preserve information predictable from the remaining modalities, while minimality should compress modality-specific information not supported by them. This naturally leads to a One-vs-All view, where each modality is characterized with respect to the remaining modalities. We propose OVA-IB, an Information Bottleneck framework for arbitrary-modality alignment. OVA-IB optimizes a tractable One-vs-All contrastive lower bound for sufficiency connected to a Dual Total Correlation-style objective, uses a parameter-free geometry-aware projection score, and derives a tractable upper-bound regularizer for minimality by bounding each representation's dependence on its own input with representation distributions induced by the remaining modalities. Experiments on classification, regression, modality-agnostic evaluation, and cross-modal retrieval benchmarks demonstrate strong and robust performance.

Contrastive Language-Audio Pretraining (CLAP) models are widely used for audio understanding and support modality-agnostic condition swapping in many zero-shot applications. However, their performance is heavily affected by the modality gap between audio and text embeddings. Existing explanations mainly attribute this gap to the cone effect, treating it as a shift between mean embeddings, yet correcting the mean alone yields only limited improvements. Alternative hypotheses, such as information imbalance and dimensionality collapse, have also been proposed, but they remain insufficiently verified and have not been thoroughly studied in the audio domain. Meanwhile, several works attempt to decompose multimodal contrastive embeddings into interpretable concepts, but none explicitly analyze the modality gap from the perspective of concept decomposition. In this work, we introduce COMET (Concept space Organization and Modality gap Explanation with PLS-SVD Transformation), a novel partial least squares singular value decomposition (PLS-SVD) framework for CLAP that unveils a broader perspective of the modality gap. Our framework reveals that only a small, interpretable subset of axes, which captures shared concepts, contributes substantially to similarity computation, and that the mean component represents only partially the modality gap. Building on this insight, we propose a simple spectral truncation method that mitigates the modality gap in a training-free manner. The method enables zero-shot audio captioning with condition swapping to approach fully supervised performance, without requiring large auxiliary memory banks or expensive computation. At the same time, it achieves substantial embedding dimensionality reduction while preserving strong performance on retrieval and audio captioning tasks.

Mainstream strategies for finetuning pretrained multimodal models often degrade out-of-distribution (OOD) robustness, a phenomenon known as catastrophic forgetting. In this paper, we develop a theoretical framework for multimodal contrastive finetuning, yielding closed-form solutions and a geometric decomposition for each strategy. This framework shows that self-distillation is more effective than other regularization approaches to retain the knowledge of the pretrained model. Our analysis reveals a largely overlooked limitation: standard Exponential Moving Average (EMA) teachers, widely used in robust finetuning, suffer from collapse. To solve this, we prove that a Weighted Moving Average (WMA) teacher maintains a persistent regularizing force over finite horizons and yields bias-free convergence in the task subspace while preserving orthogonal knowledge. These insights motivate TRACER (Trajectory-Robust Anchoring for Contrastive Encoder Regularization), which combines contrastive learning with WMA-guided multi-perspective distillation. Extensive experiments on CLIP finetuning demonstrate consistent OOD accuracy and calibration gains across three backbone architectures, and comprehensive ablations confirm that TRACER is both principled and robust to hyperparameter choices. Code is available at https://github.com/HesamAsad/TRACER.

Product images strongly influence consumer decision-making in online marketplaces. Empowered by multimodal contrastive learning, generative AI can output images that closely align with text prompts. Yet existing generative AI models do not directly optimize marketplace performance. This is a critical gap, since semantic alignment alone does not guarantee that an image will sell. To address this limitation, we propose a \textit{utility-aware multimodal contrastive learning} framework that incorporates consumer demand into a novel Utility-Aware InfoNCE loss. Optimizing this utility-aware objective guides generation toward images that are both semantically coherent and demand-enhancing. This effect arises directly from a shift in the learned image-text representation space toward demand-driven visual cues, which we also validate through the theoretical bound of the proposed objective. In downstream applications on Amazon and Airbnb, product images generated and edited by our method outperform state-of-the-art models in increasing demand and preserving fidelity, while maintaining text-image consistency. Notably, our utility-aware framework preserves inverse U-shaped demand patterns for attributes such as aesthetics and uniqueness, improving demand-based performance while preserving fidelity and semantic consistency. Human-subject experiments further validate its commercial effectiveness. As generative AI technology continues to evolve, our utility-aware component can be flexibly embedded into emerging generative models to improve direct commercial use.

Electrocardiograms (ECGs) are widely used non-invasive measurements of cardiac activity and play a central role in clinical diagnosis. Recent multimodal approaches align ECG signals with clinical reports to incorporate diagnostic semantics, but clinical reports often fail to preserve the rich physiological structure of ECG waveforms, particularly across multiple levels of abstraction ranging from coarse diagnostic categories to fine-grained morphology. To address this limitation, we formulate ECG representation learning from an information-theoretic perspective and derive a tractable objective that jointly preserves signal structure and integrates clinical semantics. Based on this principle, we propose \textbf{MERIT} (Multimodal ECG Representation via Information Theory), a dual-branch pretraining framework combining masked ECG modeling with ECG--text contrastive alignment. Extensive experiments on PTB-XL and additional benchmarks demonstrate consistent improvements over prior methods, including gains exceeding $3$ F1 on PTB-XL All and $5$ F1 on SubClass classification. In zero-shot evaluation, MERIT further improves performance by up to $+2.66\%$ AUC and $+2.11\%$ F1 on PTB-XL SubClass, while also demonstrating robustness under multiple distribution-shift settings. Moreover, leveraging the learned ECG representations for ECG-conditioned clinical text generation with large language models improves text quality across several metrics, including ROUGE and METEOR. Together, these results demonstrate that MERIT learns more informative and clinically meaningful ECG representations, particularly for fine-grained clinical applications.

Electrocardiography (ECG) is central to cardiovascular care, but conventional AI models are often restricted to common arrhythmias and may generalize poorly across populations or clinically subtle diseases. We developed ECG Contrastive Language-Image Pre-training (ECGCLIP), a signal-language contrastive learning framework that aligns ECG waveforms with expert diagnostic reports. ECGCLIP was pre-trained on 2,837,962 ECG studies from 1,324,856 patients and evaluated on a held-out internal test set plus nine independent external cohorts comprising about 1.5 million ECGs. Evaluation covered 89 downstream tasks, including 45 ECG diagnoses, 39 echocardiographic targets, and 5 rare cardiac diseases, using PRAUC as the primary metric. ECGCLIP consistently improved performance over random initialization and Merl-R18 baselines. On the internal test set, ECGCLIP-R34 achieved strong performance for atrial fibrillation (PRAUC 0.900) and ST-segment elevation myocardial infarction (PRAUC 0.383), with robust generalization across all external cohorts. It also improved low-prevalence and diagnostically elusive diseases, including Ebstein anomaly, constrictive pericarditis, dextrocardia, and cardiac amyloidosis, with internal PRAUC values of 0.253, 0.175, 0.121, and 0.201, respectively. ECGCLIP was data efficient, matching or exceeding full-dataset baseline performance with only 10% of training data. Feature visualization and saliency analysis suggested clinically meaningful representations aligned with established electrocardiographic criteria. These findings indicate that large-scale ECG-report contrastive pre-training can expand routine ECG interpretation beyond common arrhythmias toward broad cardiovascular assessment and opportunistic screening of echocardiographic and rare conditions.

In the field of multimodal fact checking, the accuracy of retrieving evidence from different modalities has a significant impact on the downstream claim verification process. Existing general multimodal retrieval methods are often constructed based on semantics, resulting in the retrieved evidence being similar but not relevant to the claim. This paper proposes a \textbf{D}ynamic \textbf{A}daptive \textbf{C}ontrastive \textbf{L}earning method for evidence \textbf{R}etrieval called DACLR to address these issues. DACLR first uses a Multimodal Large Language Model (MLLM) to uniformly convert multimodal evidence and claims into text modalities, and extracts the features of these information at event level. Then, it conducts evidence retrieval through a two-stage retrieval method of recall-rerank. DACLR enhances the model's event perception ability of the retrieval stage by optimizing the contrastive loss and mining hard negative samples. Specifically, DACLR designs three loss functions at two levels (semantic and event) based on the InfoNCE loss.Corresponding to these, three sets of hard negative sample candidates are set up. The model dynamically adjusts the ratio based on the accuracy supervision signal of intra-batch samples, allowing the model to learn the correlation between claims and positive samples at the event level without forgetting the semantic retrieval ability. Extensive comparison and ablation experiments demonstrates the effectiveness of DACLR and its internal optimization methods. Further research also prove the advantages of DACLR in the field of multimodal evidence retrieval.

Coronary artery stenosis is a common cardiovascular disease, with severe, untreated cases posing significant risks of heart attack. Although coronary (X-ray) angiograms remain the standard for stenosis diagnosis, they are invasive, time- and resource-intensive, and therefore only performed on patients with a high probability of disease based on symptoms and prior clinical tests. However, a subset of patients, especially those without symptoms, may remain undiagnosed. Detecting indications of stenosis from ECGs, which are fast, cheap, non-invasive, and thus routinely acquired even in asymptomatic patients, would support early diagnosis. However, as no reliable stenosis-specific signal has been identified in ECGs, they can not currently be used for stenosis risk stratification. To address this, we introduce StenCE, a pretraining framework, allowing stratification of patients based on features derived directly from ECGs. Evaluations across varying stenosis severity thresholds and additional ECG disease classification tasks demonstrate consistent performance improvements across different ECG encoders, outperforming previous work. The obtained models successfully detect signals for stenosis diagnosis in ECGs and are the first to achieve high performance in severe stenosis classification. The source code is available at https://github.com/NikolaCenic/ecg-stenosis-cls.

Visual decoding from brain signals is a key challenge at the intersection of computer vision and neuroscience, requiring methods that bridge neural representations and computational models of vision. We introduce a tri-modal contrastive framework for EEG-based visual decoding that aligns EEG, visual, and textual representations within a unified latent space. Our approach follows a two-stage design. First, we pre-train an EEG encoder via masked reconstruction on unlabeled trials, learning spatio-temporal regularities that transfer robustly to downstream tasks. Second, we jointly align EEG, image, and LLM-generated textual descriptions through contrastive learning, where text supervision acts as a semantic regularizer that injects linguistic structure into the shared space without overwhelming the primary EEG-image signal. The encoder integrates subject-specific adaptation, graph-attention over channels, and temporal-spatial convolutional embeddings. On the Things-EEG2 200-way zero-shot benchmark, our framework achieves 54.1% Top-1 and 83.4% Top-5 accuracy, substantially exceeding the strongest prior baseline (32.4% / 64.0%), with paired Wilcoxon tests confirming significance (p < 0.01) over all in-subject baselines. We validate generalization on Things-MEG. Analysis reveals that compact embedding geometries (CN-CLIP) outperform much larger backbones, and that decoding aligns with established neurophysiology of visual processing. This work is a critical step towards robust, semantically-grounded visual decoding from non-invasive temporal neural signals. The source code is publicly available in https://github.com/anon-eeg/eeg_image_decoding.

Existing language-image pre-training for remote sensing object detection is constrained by Monolithic Label Learning, which relies on exhaustively enumerating open-set categories via black-box data to acquire fine-grained representations, creating a dependency incompatible with the domain's inherent data scarcity. To transcend this bottleneck, we propose SLIP-RS, establishing a Structured-Attribute Decoupling Paradigm that maps the open-ended category space into a finite, physically meaningful attribute space, unlocking fine-grained discriminability via explicit structural logic. This paradigm is realized via two technical pillars: (1) Structured-Attribute Contrastive Learning, which enforces the learning of decoupled intrinsic visual logic via combinatorial attribute augmentation; and (2) Conformal Attribute Reliability Engine, which leverages conformal prediction theory to rigorously distill high-fidelity supervision from noisy sources, yielding RS-Attribute-15M, the largest dataset with over 15 million attribute annotations. Extensive experiments demonstrate that SLIP-RS establishes unprecedented performance in fine-grained detection and cross-domain generalization, validating structured attributes as a vital foundation for remote sensing. Code: https://github.com/facias914/SLIP-RS.

Despite the impressive results achieved by multimodal large language models (MLLMs), their training typically relies on jointly curated multimodal data, requiring substantial human effort to construct multi-way aligned datasets and thereby limiting scalability across domains. In this work, we explore training MLLMs by only leveraging multiple paired modalities as a surrogate for the full joint multimodal distribution. Specifically, we first provide a theoretical analysis of the conditions under which the representations are identifiable with only observing pairwise modalities. Building on this analysis, we propose a representation learning framework for aligning latent representations across modalities using only pairwise data. The framework consists of two stages: latent representation alignment and cross-modal recomposition. Specifically, in the first stage, we learn the shared latent space across modalities by both self-modal reconstruction and pair-wise contrastive learning. We also incorporate an inductive bias in the contrastive learning process by partially aligning and minimal latent specification. In stage two, we integrate the encoder of newly introduced modalities with the decoders of the pre-trained modalities to facilitate cross-modal transfer and generation. We evaluate our method by newly adding 3D point clouds and tactile modalities into pre-trained MLLMs with three modality pairs and show that, by learning an aligned latent representation space, our model achieves strong cross-modal performance.

Collaborative game-based learning environments offer rich opportunities for small-group knowledge construction, yet automatically predicting student collaboration satisfaction remains challenging. A critical barrier is modality degradation: in educational deployments, individual modalities such as eye gaze exhibit inconsistent informativeness across student cohorts, causing implicit attention-based fusion to produce brittle multimodal representations. We propose the Affinity-Aligned Multimodal Learning Analytics (AAMLA) framework, whose core contribution is the Cross-modal Affinity-guided Modality Alignment (CAMA) module, which explicitly models inter-modal relationships via affinity matrices and enforces cross-modal consistency through contrastive learning, enabling adaptive suppression of uninformative modalities without discarding them. AAMLA further applies modality-specific projection layers to map heterogeneous features, including facial action units, head pose, eye gaze, and interaction trace logs, into a unified semantic space prior to alignment. Experiments on 50 middle school students in the EcoJourneys collaborative learning environment demonstrate consistent improvements over unimodal baselines and prior cross-attention approaches under standard and modality degradation conditions, with SHAP and t-SNE analyses confirming that CAMA produces robust, interpretable cross-modal representations for student collaboration modeling.

Medical referring image segmentation (MRIS) requires pixel-level masks aligned with textual descriptions of anatomical locations, making annotation costly in low-label regimes. Semi-supervised learning (SSL) can mitigate this burden by leveraging unlabeled data, but its success hinges on maintaining reliable image-text alignment under perturbations. Most existing SSL-based referred segmentation methods use either independent or simplistic multi-modal perturbations (e.g., left-right flips), without fully addressing cross-modal alignment under strong augmentation, while CutMix, highly effective in single-modal SSL, remains underexplored in multi-modal settings due to its tendency to disrupt image-text coherence. We propose Semi-MedRef, a teacher-student SSL framework designed to explicitly maintain consistency between medical images and positional language through three alignment-preserving components: T-PatchMix, a cross-modal CutMix-style augmentation that synchronizes patch mixing with referring expressions via position-constrained and probability-driven rules; PosAug, a position-aware text augmentation that masks or fuzzes anatomical phrases; and ITCL, a position-guided image-text contrastive learning module, which leverages positional pseudo-labels to construct soft anatomical positives and strengthen medically grounded cross-modal alignment. Experiments on QaTa-COV19 and MosMedData+ demonstrate that Semi-MedRef consistently outperforms both fully supervised and semi-supervised baselines across all label regimes.

Contrastively pre-trained Vision-Language Models (VLMs) serve as powerful feature extractors. Yet, their shared latent spaces are prone to structural anomalies and act as repositories for non-semantic, multi-modal noise. To address this phenomenon, we employ spectral decomposition of covariance matrices to decompose the VLM latent space into a multi-modal semantic signal component and a shared noise subspace. We observe that this noise geometry exhibits strong subgroup invariance across distinct data subsets. Crucially, pruning these shared noise dimensions is mainly harmless, preserving or actively improving downstream task performance. By isolating true semantic signals from artifactual noise, this work provides new mechanistic insights into the representational structure of modern VLMs, suggesting that a substantial fraction of their latent geometry is governed by shared, architecture-level noise rather than task-relevant semantics alone.

Deep learning and multi-modal fusion have demonstrated transformative potential in medical diagnosis by integrating diverse data sources. However, accurate prognosis for ischemic stroke remains challenging due to limitations in existing multi-modal approaches. First, current methods are predominantly confined to dual-modal fusion, lacking a framework that effectively integrates the trifecta of medical images, structured clinical data, and unstructured text. Second, they often fail to establish deep bidirectional interactions between modalities; To address these critical gaps, this paper proposes a novel tri-modal fusion model for ischemic stroke prognosis. Our approach first enriches the data representation by employing a Large Language Model (LLM) to automatically generate semi-structured diagnostic text from brain MRIs. This process not only addresses the scarcity of expert annotations but also serves as a regularized semantic enhancement, improving multimodal fusion robustness. Furthermore, we design a core component termed the Vision-Conditioned Dual Alignment Fusion Module (VDAFM), which strategically uses visual features as a conditional prior to guide fine-grained interaction with the generated text. This module achieves a dynamic and profound fusion through a dual semantic alignment loss, effectively mitigating modal heterogeneity. Extensive experiments on a real-world clinical dataset demonstrate that our model achieves state-of-the-art performance.

Fine-grained Vision-Language Pre-training (FVLP) demonstrates significant potential in 3D medical image understanding by aligning anatomy-level visual representations with corresponding textual descriptions. However, existing FVLP paradigms often suffer from severe representation collapse in the textual embedding space, where text embeddings of distinct anatomical structures become highly clustered and indistinguishable. This distributional degeneracy renders the model hypersensitive to prompt variations, hindering reliable clinical deployment. To address these challenges, we propose a novel Cross-Anatomy Global-Local Contrastive Learning framework (CA-GCL). CA-GCL introduces a global contrastive objective that enforces separation between anatomical categories in the latent space, effectively counteracting the aggregation tendency induced by local alignment. Furthermore, we incorporate a clinical-aware text augmentation strategy based on permutation invariance and partial completeness to enhance robustness against descriptive incompleteness. Extensive evaluations on the CT-RATE and Rad-ChestCT datasets show that CA-GCL achieves comparable zero-shot abnormality detection performance to existing VLP paradigms, while demonstrating substantially better robustness to prompt variations: on canonical templates it obtains higher mean AUC with lower variance, and on non-canonical templates it remains stable whereas baselines degrade markedly. These results validate CA-GCL as an effective framework for robust 3D medical image understanding.

Despite the recent success of Multimodal Foundation Models (FMs), their reliance on massive paired datasets limits their applicability in low-data and rare-scenario settings where aligned data is scarce and expensive. A key bottleneck is the adoption of an instance-level formulation, which learns alignment by maximizing correlation between individual image-text pairs while neglecting the underlying geometric structure across modalities resulting in a modality gap across input modalities. In this paper, we propose a combinatorial paradigm for multimodal alignment that moves beyond pairwise learning and introduce the \emph{Submodular Modality Aligner (SMA)}, which treats multiple augmentations and descriptions of an entity as a set, leveraging multiple descriptions of the data to capture richer cross-modal structure. We instantiate SMA using a principled objective based on Submodular Mutual Information (SMI), which jointly maximizes inter-modality mutual information while reducing cross-modal divergence. This formulation enables the model to effectively utilize multiple positive associations and extract significantly more information from limited data. We evaluate SMA on 14 zero-shot classification and retrieval tasks from the CLIP benchmark and demonstrate consistent gains in the low-data regime. Notably, SMA achieves strong multimodal generalization using only tens of thousands of samples. This is orders of magnitude fewer than standard approaches. Our results highlight the importance of set-based formulations and submodular objectives for data-efficient multimodal learning.

Pertussis booster vaccination produces immune responses that vary widely across individuals in both peak magnitude and long-term durability. These two phases are governed by partly distinct biological compartments:peak reflects acute B-cell activation and antibody secretion, while durability reflects the establishment of long-term humoral memory. Yet most computational models target only one, missing the full boost-and-wane trajectory. Jointly predicting both is non-trivial because the two endpoints are biologically dissociated rather than redundant; samples are small, modalities are heterogeneous with structured missingness, and the two tasks rely on different measurement windows. We propose a multi-task contrastive multimodal fusion architecture combining frozen TabPFN-v2 per-modality encoders, a dual-label supervised contrastive loss that treats two subjects as a positive pair if they agree on the Task 1 label or the Task 2 label, modality dropout calibrated to empirical missingness, and missingness-masked attention fusion. Applied to a curated subset of the CMI-PB pertussis booster dataset (n = 158 subjects, four modalities, 44.9% with at least one modality missing; Spearman r = -0.58 between peak and durability, n = 96), the model achieves test AUROC 0.797 (95% CI [0.621, 0.948]) for peak response and 0.755 (95% CI [0.519, 0.945]) for durability, with both significant under joint label permutation (N = 1000; p = 0.002 and p = 0.045). Across logistic regression, XGBoost, and MLP baselines on raw features and on TabPFN embeddings, the proposed model is the only one whose 95% CIs lie above chance on both tasks simultaneously. Per-modality contribution analyses recover task-specific modality contributions consistent with the underlying immunology: peak prediction is carried by cytokine signatures, while durability is carried by baseline antibody features.

Query-based image retrieval (QBIR) requires retrieving relevant images given diverse and often stylistically heterogeneous queries, such as sketches, artworks, or low-resolution previews. While large-scale vision--language representation models (VLRMs) like CLIP offer strong zero-shot retrieval performance, they struggle with distribution shifts caused by unseen query styles. In this paper, we propose the Hypernetwork-driven Style-adaptive Retrieval (Hystar), a lightweight framework that dynamically adapts model weights to each query's style. Hystar employs a hypernetwork to generate singular-value perturbations ($ΔS$) for attention layers, enabling flexible per-input adaptation, while static singular-value offsets on MLP layers ensure cross-style stability. To better handle semantic confusions across styles, we design StyleNCE as part of Hystar, an optimal-transport-weighted contrastive loss that emphasizes hard cross-style negatives. Extensive experiments on multi-style retrieval and cross-style classification benchmarks demonstrate that Hystar consistently outperforms strong baselines, achieving state-of-the-art performance while being parameter-efficient and stable across styles.

Due to the potential for exploratory reasoning of Latent Visual Reasoning, recent works tend to enable MLLMs (Multimodal Large Language Models) to perform visual reasoning by propagating continuous hidden states instead of decoding intermediate steps into discrete tokens. However, existing works typically rely on hard alignment objectives to force latent representations to match predefined visual features, thereby severely limiting the exploratory of latent reasoning process. To address this problem, we propose CoLVR (Contrastive Optimization for Latent Visual Reasoning). To obtain a more exploratory visual reasoning, CoLVR introduces a latent contrastive training framework. Firstly, CoLVR learns diverse and exploratory representations with a latent contrastive objective guided by angle-based perturbation, which expands the semantic latent space and avoids over-constrained embedding. Then, CoLVR employs a latent trajectory contrastive reward for RL (Reinforcement Learning) post-training to enable fine-grained optimization of latent visual reasoning process and thus fostering diverse reasoning behaviors. Experiments demonstrate that CoLVR significantly enhances the exploratory capability of latent representations, achieving average improvements of 5.83% on VSP and 8.00% on Jigsaw, while also outperforming existing latent models on out of domain benchmarks, with a 3.40% gain on MMStar. The data, codes, and models are released at https://github.com/Oscar-dzy/CoLVR.

Contrastive language-image pretraining (CLIP) suffers from two structural weaknesses: the symmetric InfoNCE loss discards the relative ordering among unmatched in-batch pairs, and global pooling collapses the visual representation into a semantic bottleneck that is poorly sensitive to fine-grained local structure. RANKCLIP partially addresses the first issue with a list-wise Plackett-Luce ranking-consistency loss, but its model is strictly first-order and inherits the second weakness untouched. We propose DINORANKCLIP, a pretraining framework that addresses both jointly. Our principal contribution is injecting a frozen DINOv3 teacher into the contrastive trunk through a dual-branch lightweight student and a multi-scale fusion module with channel-spatial attention, a self-attention refiner, and a conflict-aware gate that preserves the cross-modal alignment up to first order. Complementarily, we introduce a high-order Plackett-Luce ranking model in which the per-position utility is augmented with attention-parameterised pairwise and tuple-wise transition terms; the family contains CLIP and RANKCLIP as nested zero-order and first-order special cases, and the optimal order on every benchmark is $R^*=3$. The full empirical study -- order sweep, Fine-grained Probe on five datasets, four-node Modality-Gap analysis, six-variant Fusion ablation -- fits in 72 hours on a single eight-GPU H100 node and trains entirely on Conceptual Captions 3M. DINORANKCLIP consistently outperforms CLIP, CyCLIP, ALIP, and RANKCLIP under matched compute, with the largest relative gains on the fine-grained and out-of-distribution evaluations that most directly stress local structural reasoning.

The condition monitoring (CM) of synthetic fibre ropes (SFRs) used in offshore, maritime, and industrial settings demands more than a classifier: inspectors need continuous severity estimates, maintenance recommendations, anomaly flags, deterioration timelines, and automated reports, all from a single inspection image. We present DART (Damage Assessment via Rope Transformer), a vision-language foundation model that addresses the full rope inspection workflow through a unified multi-task architecture. DART extends the Joint-Embedding Predictive Architecture (JEPA) to the cross-modal domain by coupling a Vision Transformer (ViT-H/14) with Llama-3.2-3B-Instruct via a Severity-Conditioned Cross-Modal Fusion (SC-CMF) module. Three architectural innovations drive the model's versatility: (1) HD-MASK, a saliency-guided masking strategy that focuses self-supervised reconstruction on damage-dense patches; (2) per-class learnable severity gates that adaptively weight language grounding by damage category; and (3) a Contrastive Damage Disentanglement (CDD) loss that shapes the embedding space to simultaneously encode damage type, severity ordering, and cross-modal semantics. Trained once on 4,270 images spanning 14 fine-grained rope damage classes, the frozen DART backbone supports downstream tasks without any task-specific fine-tuning: damage classification (93.22 % accuracy, 91.04 % macro-F1, +38.5 pp over a vision-only baseline), continuous severity regression (Spearman rho = 0.94, within-1-ordinal accuracy 99.6 %), few-shot recognition (89.2 % macro-F1 at 20 shots). These results demonstrate that DART functions as a general-purpose CM backbone that goes well beyond classification, providing actionable inspection intelligence from a single shared representation.

EEG-based visual neural decoding aims to align neural responses with visual stimuli for tasks such as image retrieval. However, limited paired data and a fundamental mismatch between high-fidelity digital images and biological visual perception - distorted by retinotopic mapping and subject-specific neuroanatomy - severely impede cross-modal alignment. To address this, we propose MB2L, a Multi-Level Bidirectional Biomimetic Learning framework that incorporates structured physiological inductive biases into representation learning. Specifically, we propose Adaptive Blur with Visual Priors to mitigate perceptual-structural mismatch by reweighting visual inputs according to retinotopic priors. We further propose Biomimetic Visual Feature Extraction to learn multi-level visual representations consistent with hierarchical cortical processing, enhancing subject-invariant encoding. These modules are jointly optimized via Multi-level Bidirectional Contrastive Learning, which aligns EEG and visual features in a shared semantic space through bidirectional contrastive objectives. Experiments show MB2L achieves 80.5% Top-1 and 97.6% Top-5 accuracy on zero-shot EEG-to-image retrieval, significantly outperforming prior methods and demonstrating strong generalization across subjects and experimental settings.

Ultrasound foundation models have achieved strong performance on structured prediction tasks but remain exclusively vision-based, limiting zero-shot and few-shot transfer to novel tasks where task-specific annotation is scarce. We address this gap with EchoCare-CLIP, a CLIP-style dual-encoder contrastive framework that aligns ultrasound images with clinical text in a shared embedding space. We curate a multi-organ corpus of over 16K image-text pairs spanning breast, liver, lung, and thyroid, with over 78% of captions derived from expert-annotated reports, and complement the remainder with a three-tier template-based and LLM-based caption generation pipeline. We evaluate model configurations spanning two text encoder families (CLIP, BioClinicalBERT) and two caption strategies (template-based, LLM-generated) against OpenAI CLIP and BiomedCLIP baselines. Our trained models consistently improve cross-modal alignment over baselines, with the best configuration achieving a paired alignment score of 0.682. However, stronger alignment does not guarantee better downstream performance: CLIP-based variants with partial fine-tuning achieve the strongest zero-shot classification on external held-out datasets (0.709 on BUSI; 0.626 on AULI), while full end-to-end fine-tuning degrades transfer due to overfitting. On linear probing and few-shot adaptation, model rankings are dataset-dependent, reflecting a trade-off between domain adaptation and representational generalizability. We further show that template-based captions match or outperform LLM-generated captions, suggesting lexical diversity is not a proxy for caption quality. Taken together, our results demonstrate that ultrasound vision-language alignment is achievable from public data alone, but robust clinical transfer requires careful balancing of domain adaptation, encoder capacity, and caption supervision quality.

Federated Multimodal Learning (FML) trains multimodal models across decentralized clients while keeping their image-text pairs private. However, joint embedding training entangles forgotten knowledge across both modalities and client gradient subspaces, hindering federated unlearning. Previous federated unlearning approaches neither sever the cross-modal reconstruction channel mediated by bilinear coupling nor separate forget-exclusive update directions from those shared with retained clients. We identify an Anchor Principle for federated multimodal contrastive unlearning: forgotten alignments persist through three residual anchors arising from bilinear cross-modal coupling, principal-angle subspace entanglement, and continued federated updates. At the modality level, we show that bilateral displacement of both visual and language branches closes the cross-modal reconstruction channel. Correspondingly, our method addresses subspace entanglement through Cosine--Sine decomposition of client-update subspaces, isolating forget-exclusive directions from retain support. Moreover, we propose a direction-selective Forget Lock that bounds residual drift across rounds. Combining these strategies, we present EASE, an Entanglement-Aware Subspace Excision framework that closes all three anchor channels under a unified design. EASE demonstrates consistent superiority across multiple datasets and unlearning scenarios, for instance, matching the retrain reference to within 0.2 and 4.2 R@1 points on the forget and retain sides under client unlearning on Flickr30K with CLIP-B/32.

Automated pediatric electrocardiogram (ECG) interpretation remains challenging because developmental differences in heart rate, intervals, and waveforms limit the transferability of models trained mainly on adult data, while expert-labeled pediatric ECG cohorts are scarce. We propose PEACE (Pediatric-Adult ECG Alignment via Cross-modal Enhancement), an adult-to-pediatric ECG transfer framework pretrained on MIMIC-IV ECGs and adapted to pediatric targets. PEACE integrates label-specific bidirectional contrastive learning (LSBC) to align ECG representations with diagnostic semantics and curriculum adaptive fusion (CAF) to stabilize optimization under limited pediatric supervision. Label-conditioned short text descriptors provide auxiliary semantic supervision during training, whereas inference requires ECG signals only. On ZZU-pECG, PEACE achieves macro-average AUCs of 59.39%, 81.74%, and 91.56% under zero-shot, 50-shot, and full fine-tuning settings, respectively, outperforming ECG-only, multimodal, and generic domain adaptation baselines including DANN and MMD. On PTB-XL, it reaches 96.90% macro-average AUC after full fine-tuning over nine harmonized labels with nonzero mapped incidence. Gradient-based attention maps show increased saliency around QRS voltage and morphology regions for chamber-related RVH and around QRS-to-T/repolarization intervals for LQTS, broadly consistent with ECG regions commonly inspected during routine interpretation. These results suggest that adult-scale ECG pretraining coupled with rhythm, morphology, and ST-T repolarization semantic descriptors improves transferable pediatric diagnosis under label scarcity while preserving clinically interpretable waveform focus.