Multimodal Disentangled Representation Learning

Multimodal affective computing aims to predict humans' sentiment, emotion, intention, and opinion using language, acoustic, and visual modalities. However, current models often learn spurious correlations that harm generalization under distribution shifts or noisy modalities. To address this, we propose a causal modality-invariant representation (CmIR) learning framework for robust multimodal learning. At its core, we introduce a theoretically grounded disentanglement method that separates each modality into causal invariant representation' and environment-specific spurious representation' from a causal inference perspective. CmIR ensures that the learned invariant representations retain stable predictive relationships with labels across different environments while preserving sufficient information from the raw inputs via invariance constraint, mutual information constraint, and reconstruction constraint. Experiments across multiple multimodal benchmarks demonstrate that CmIR achieves state-of-the-art performance. CmIR particularly excels on out-of-distribution data and noisy data, confirming its robustness and generalizability.

Data collected from the physical world is always a combination of multiple sources: an underlying signal from the physical process of interest and a signal from measurement-dependent artifacts from the sensor or instrument. This secondary signal acts as a confounding factor, limiting our ability to extract information about the physics underlying the phenomena we observe. Furthermore, it complicates the combination of observations in heterogeneous or multi-instrument settings. We propose a deep learning framework that leverages overlapping observations, a dual-encoder architecture, and a counterfactual generation objective to disentangle these factors of variation. The resulting representations explicitly separate intrinsic signals from sensor-specific distortions and noise, and can be used for counterfactual view generation, parameter inference unconfounded by measurement distortions, and instrument-independent similarity search. We demonstrate the effectiveness of our approach on astrophysical galaxy images from the DESI Legacy Imaging Survey (Legacy) and the Hyper Suprime-Cam (HSC) Survey as a representative multi-instrument setting. This framework provides a general recipe for scientific and multi-modal self-supervised pretraining: construct training pairs from overlapping observations of the same physical system, treat sensor- or modality-specific effects as augmentations, and learn invariant representations through counterfactual generation.

Medical foundation models (MFMs) aim to learn universal representations from multimodal medical images that can generalize effectively to diverse downstream clinical tasks. However, most existing MFMs suffer from information ambiguity that blends multimodal representations in a single embedding space, leading to the degradation of modality specificity and diversity. In this paper, we propose M-IDoL, a self-supervised MFM that introduces Information Decomposition for multimodal representation Learning via two objectives: i) maximizing inter-modality entropy by dispersing multimodal representations into separable Mixture-of-Experts (MoE) subspaces to achieve representation specificity across modalities; and ii) minimizing intra-modality uncertainty by performing fine-grained semantic discrimination within each MoE subspace to enrich representation diversity per modality. By pre-training on 1.15 million medical images, M-IDoL i) delivers superior generalization across 21 downstream clinical tasks, outperforming 20 foundation models on five imaging modalities (e.g., X-ray, fundus, OCT, dermoscopy and pathology), and ii) learns modality-specific and diverse representations, showing clearer separation of feature clusters across modalities and finer-grained feature discrimination within each modality.

Multimodal imaging analysis often relies on joint latent representations, yet these approaches rarely define what information is shared versus modality-specific. Clarifying this distinction is clinically relevant, as it delineates the irreducible contribution of each modality and informs rational acquisition strategies. We propose a subspace decomposition framework that reframes multimodal fusion as a problem of orthogonal subspace separation rather than translation. We decompose Prostate-Specific Membrane Antigen (PSMA) PET uptake into an MRI-explainable physiological envelope and an orthogonal residual reflecting signal components not expressible within the MRI feature manifold. Using multiparametric MRI, we train an intensity-based, non-spatial implicit neural representation (INR) to map MRI feature vectors to PET uptake. We introduce a projection-based regularization using singular value decomposition to penalize residual components lying within the span of the MRI feature manifold. This enforces mathematical orthogonality between tissue-level physiological properties (structure, diffusion, perfusion) and intracellular PSMA expression. Tested on 13 prostate cancer patients, the model demonstrates that residual components spanned by MRI features are absorbed into the learned envelope, while the orthogonal residual is largest in tumour regions. This indicates that PSMA PET contains signal components not recoverable from MRI-derived physiological descriptors. The resulting decomposition provides a structured characterization of modality complementarity grounded in representation geometry rather than image translation.

Multimodal representation learning is commonly built on a shared-private decomposition, treating latent information as either common to all modalities or specific to one. This binary view is often inadequate: many factors are shared by only subsets of modalities, and ignoring such partial sharing can over-align unrelated signals and obscure complementary information. We propose Hierarchical Contrastive Learning (HCL), a framework that learns globally shared, partially shared, and modality-specific representations within a unified model. HCL combines a hierarchical latent-variable formulation with structural sparsity and a structure-aware contrastive objective that aligns only modalities that genuinely share a latent factor. Under uncorrelated latent variables, we prove identifiability of the hierarchical decomposition, establish recovery guarantees for the loading matrices, and derive parameter estimation and excess-risk bounds for downstream prediction. Simulations show accurate recovery of hierarchical structure and effective selection of task-relevant components. On multimodal electronic health records, HCL yields more informative representations and consistently improves predictive performance.

Learning a robust Variational Autoencoder (VAE) is a fundamental step for many deep learning applications in medical image analysis, such as MRI synthesizes. Existing brain VAEs predominantly focus on single-modality data (i.e., T1-weighted MRI), overlooking the complementary diagnostic value of other modalities like T2-weighted MRIs. Here, we propose a modality-aware and anatomically grounded 3D vector-quantized VAE (VQ-VAE) for reconstructing multi-modal brain MRIs. Called NeuroQuant, it first learns a shared latent representation across modalities using factorized multi-axis attention, which can capture relationships between distant brain regions. It then employs a dual-stream 3D encoder that explicitly separates the encoding of modality-invariant anatomical structures from modality-dependent appearance. Next, the anatomical encoding is discretized using a shared codebook and combined with modality-specific appearance features via Feature-wise Linear Modulation (FiLM) during the decoding phase. This entire approach is trained using a joint 2D/3D strategy in order to account for the slice-based acquisition of 3D MRI data. Extensive experiments on two multi-modal brain MRI datasets demonstrate that NeuroQuant achieves superior reconstruction fidelity compared to existing VAEs, enabling a scalable foundation for downstream generative modeling and cross-modal brain image analysis.

Learning interpretable multimodal representations inherently relies on uncovering the conditional dependencies between heterogeneous features. However, sparse graph estimation techniques, such as Graphical Lasso (GLasso), to visual-linguistic domains is severely bottlenecked by high-dimensional noise, modality misalignment, and the confounding of shared versus category-specific topologies. In this paper, we propose Cross-Modal Graphical Lasso (CM-GLasso) that overcomes these fundamental limitations. By coupling a novel text-visualization strategy with a unified vision-language encoder, we strictly align multimodal features into a shared latent space. We introduce a cross-attention distillation mechanism that condenses high-dimensional patches into explicit semantic nodes, naturally extracting spatial-aware cross-modal priors. Furthermore, we unify tailored GLasso estimation and Common-Specific Structure Learning (CSSL) into a joint objective optimized via the Alternating Direction Method of Multiplier (ADMM). This formulation guarantees the simultaneous disentanglement of invariant and class-specific precision matrices without multi-step error accumulation. Extensive experiments across eight benchmarks covering both natural and medical domains demonstrate that CM-GLasso establishes a new state-of-the-art in generative classification and dense semantic segmentation tasks.

Multimodal emotion recognition in conversations aims to infer utterance-level emotions by jointly modeling textual, acoustic, and visual cues within context. Despite recent progress, key challenges remain, including redundant cross-modal information, imperfect semantic alignment, and insufficient modeling of high-order speaker interactions. To address these issues, we propose a framework that combines dual-space feature disentanglement with dual-branch graph learning. A shared encoder and modality-specific encoders are used to separate modality-invariant and modality-specific representations. The invariant features are modeled by a Fourier graph neural network to capture global consistency and complementary patterns, with a frequency-domain contrastive objective to enhance discriminability. In parallel, a speaker-aware hypergraph is constructed over modality-specific features to model high-order interactions, along with a speaker-consistency constraint to maintain coherent semantics. Finally, the two branches are fused for utterance-level emotion prediction. Experiments on IEMOCAP and MELD demonstrate that the proposed method achieves superior performance over strong baselines, validating its effectiveness.

Person Re-Identification (ReID) faces severe challenges from modality discrepancy and clothing variation in long-term surveillance scenario. While existing studies have made significant progress in either Visible-Infrared ReID (VI-ReID) or Clothing-Change ReID (CC-ReID), real-world surveillance system often face both challenges simultaneously. To address this overlooked yet realistic problem, we define a new task, termed Cross-Modality Clothing-Change Re-Identification (CMCC-ReID), which targets pedestrian matching across variations in both modality and clothing. To advance research in this direction, we construct a new benchmark SYSU-CMCC, where each identity is captured in both visible and infrared domains with distinct outfits, reflecting the dual heterogeneity of long-term surveillance. To tackle CMCC-ReID, we propose a Progressive Identity Alignment Network (PIA) that progressively mitigates the issues of clothing variation and modality discrepancy. Specifically, a Dual-Branch Disentangling Learning (DBDL) module separates identity-related cues from clothing-related factors to achieve clothing-agnostic representation, and a Bi-Directional Prototype Learning (BPL) module performs intra-modality and inter-modality contrast in the embedding space to bridge the modality gap while further suppressing clothing interference. Extensive experiments on the SYSU-CMCC dataset demonstrate that PIA establishes a strong baseline for this new task and significantly outperforms existing methods.

Molecular property prediction constitutes a cornerstone of drug discovery and materials science, necessitating models capable of disentangling complex structure-property relationships across diverse molecular modalities. Existing approaches frequently exhibit entangled representations--conflating structural, chemical, and functional factors--thereby limiting interpretability and transferability. Furthermore, conventional methods inadequately exploit complementary information from graphs, sequences, and geometries, often relying on naive concatenation that neglects inter-modal dependencies. In this work, we propose DMMRL, which employs variational autoencoders to disentangle molecular representations into shared (structure-relevant) and private (modality-specific) latent spaces, enhancing both interpretability and predictive performance. The proposed variational disentanglement mechanism effectively isolates the most informative features for property prediction, while orthogonality and alignment regularizations promote statistical independence and cross-modal consistency. Additionally, a gated attention fusion module adaptively integrates shared representations, capturing complex inter-modal relationships. Experimental validation across seven benchmark datasets demonstrates DMMRL's superior performance relative to state-of-the-art approaches. The code and data underlying this article are freely available at https://github.com/xulong0826/DMMRL.

Multimodal image registration is a fundamental task and a prerequisite for downstream cross-modal analysis. Despite recent progress in shared feature extraction and multi-scale architectures, two key limitations remain. First, some methods use disentanglement to learn shared features but mainly regularize the shared part, allowing modality-private cues to leak into the shared space. Second, most multi-scale frameworks support only a single transformation type, limiting their applicability when global misalignment and local deformation coexist. To address these issues, we formulate hybrid multimodal registration as jointly learning a stable shared feature space and a unified hybrid transformation. Based on this view, we propose HRNet, a Hybrid Registration Network that couples representation disentanglement with hybrid parameter prediction. A shared backbone with Modality-Specific Batch Normalization (MSBN) extracts multi-scale features, while a Cross-scale Disentanglement and Adaptive Projection (CDAP) module suppresses modality-private cues and projects shared features into a stable subspace for matching. Built on this shared space, a Hybrid Parameter Prediction Module (HPPM) performs non-iterative coarse-to-fine estimation of global rigid parameters and deformation fields, which are fused into a coherent deformation field. Extensive experiments on four multimodal datasets demonstrate state-of-the-art performance on rigid and non-rigid registration tasks. The code is available at the project website.

A recent cutting-edge topic in multimodal modeling is to unify visual comprehension and generation within a single model. However, the two tasks demand mismatched decoding regimes and visual representations, making it non-trivial to jointly optimize within a shared feature space. In this work, we present Cheers, a unified multimodal model that decouples patch-level details from semantic representations, thereby stabilizing semantics for multimodal understanding and improving fidelity for image generation via gated detail residuals. Cheers includes three key components: (i) a unified vision tokenizer that encodes and compresses image latent states into semantic tokens for efficient LLM conditioning, (ii) an LLM-based Transformer that unifies autoregressive decoding for text generation and diffusion decoding for image generation, and (iii) a cascaded flow matching head that decodes visual semantics first and then injects semantically gated detail residuals from the vision tokenizer to refine high-frequency content. Experiments on popular benchmarks demonstrate that Cheers matches or surpasses advanced UMMs in both visual understanding and generation. Cheers also achieves 4x token compression, enabling more efficient high-resolution image encoding and generation. Notably, Cheers outperforms the Tar-1.5B on the popular benchmarks GenEval and MMBench, while requiring only 20% of the training cost, indicating effective and efficient (i.e., 4x token compression) unified multimodal modeling. We will release all code and data for future research.

Although diffusion models have achieved remarkable progress in multi-modal magnetic resonance imaging (MRI) translation tasks, existing methods still tend to suffer from anatomical inconsistencies or degraded texture details when handling arbitrary missing-modality scenarios. To address these issues, we propose a latent diffusion-based multi-modal MRI translation framework, termed MSG-LDM. By leveraging the available modalities, the proposed method infers complete structural information, which preserves reliable boundary details. Specifically, we introduce a style--structure disentanglement mechanism in the latent space, which explicitly separates modality-specific style features from shared structural representations, and jointly models low-frequency anatomical layouts and high-frequency boundary details in a multi-scale feature space. During the structure disentanglement stage, high-frequency structural information is explicitly incorporated to enhance feature representations, guiding the model to focus on fine-grained structural cues while learning modality-invariant low-frequency anatomical representations. Furthermore, to reduce interference from modality-specific styles and improve the stability of structure representations, we design a style consistency loss and a structure-aware loss. Extensive experiments on the BraTS2020 and WMH datasets demonstrate that the proposed method outperforms existing MRI synthesis approaches, particularly in reconstructing complete structures. The source code is publicly available at https://github.com/ziyi-start/MSG-LDM.

Depression is a severe mental disorder, and reliable identification plays a critical role in early intervention and treatment. Multimodal depression detection aims to improve diagnostic performance by jointly modeling complementary information from multiple modalities. Recently, numerous multimodal learning approaches have been proposed for depression analysis; however, these methods suffer from the following limitations: 1) inter-modal inconsistency and depression-unrelated interference, where depression-related cues may conflict across modalities while substantial irrelevant content obscures critical depressive signals, and 2) diverse individual depressive presentations, leading to individual differences in modality and cue importance that hinder reliable fusion. To address these issues, we propose Individual-aware Multimodal Depression-related Representation Learning Framework (IDRL) for robust depression diagnosis. Specifically, IDRL 1) disentangles multimodal representations into a modality-common depression space, a modality-specific depression space, and a depression-unrelated space to enhance modality alignment while suppressing irrelevant information, and 2) introduces an individual-aware modality-fusion module (IAF) that dynamically adjusts the weights of disentangled depression-related features based on their predictive significance, thereby achieving adaptive cross-modal fusion for different individuals. Extensive experiments demonstrate that IDRL achieves superior and robust performance for multimodal depression detection.

Medical image synthesis is crucial for alleviating data scarcity and privacy constraints. However, fine-tuning general text-to-image (T2I) models remains challenging, mainly due to the significant modality gap between complex visual details and abstract clinical text. In addition, semantic entanglement persists, where coarse-grained text embeddings blur the boundary between anatomical structures and imaging styles, thus weakening controllability during generation. To address this, we propose a Visually-Guided Text Disentanglement framework. We introduce a cross-modal latent alignment mechanism that leverages visual priors to explicitly disentangle unstructured text into independent semantic representations. Subsequently, a Hybrid Feature Fusion Module (HFFM) injects these features into a Diffusion Transformer (DiT) through separated channels, enabling fine-grained structural control. Experimental results in three datasets demonstrate that our method outperforms existing approaches in terms of generation quality and significantly improves performance on downstream classification tasks. The source code is available at https://github.com/hx111/VG-MedGen.

RGB-Thermal (RGB-T) semantic segmentation is essential for robotic systems operating in low-light or dark environments. However, traditional approaches often overemphasize modality balance, resulting in limited robustness and severe performance degradation when sensor signals are partially missing. Recent advances such as cross-modal knowledge distillation and modality-adaptive fine-tuning attempt to enhance cross-modal interaction, but they typically decouple modality fusion and modality adaptation, requiring multi-stage training with frozen models or teacher-student frameworks. We present RTFDNet, a three-branch encoder-decoder that unifies fusion and decoupling for robust RGB-T segmentation. Synergistic Feature Fusion (SFF) performs channel-wise gated exchange and lightweight spatial attention to inject complementary cues. Cross-Modal Decouple Regularization (CMDR) isolates modality-specific components from the fused representation and supervises unimodal decoders via stop-gradient targets. Region Decouple Regularization (RDR) enforces class-selective prediction consistency in confident regions while blocking gradients to the fusion branch. This feedback loop strengthens unimodal paths without degrading the fused stream, enabling efficient standalone inference at test time. Extensive experiments demonstrate the effectiveness of RTFDNet, showing consistent performance across varying modality conditions. Our implementation will be released to facilitate further research. Our source code are publicly available at https://github.com/curapima/RTFDNet.

Cross-modal alignment is a crucial task in multimodal learning aimed at achieving semantic consistency between vision and language. This requires that image-text pairs exhibit similar semantics. Traditional algorithms pursue embedding consistency to achieve semantic consistency, ignoring the non-semantic information present in the embedding. An intuitive approach is to decouple the embeddings into semantic and modality components, aligning only the semantic component. However, this introduces two main challenges: (1) There is no established standard for distinguishing semantic and modal information. (2) The modality gap can cause semantic alignment deviation or information loss. To align the true semantics, we propose a novel cross-modal alignment algorithm via Constrained Decoupling and Distribution Sampling (CDDS). Specifically, (1) A dual-path UNet is introduced to adaptively decouple the embeddings, applying multiple constraints to ensure effective separation. (2) A distribution sampling method is proposed to bridge the modality gap, ensuring the rationality of the alignment process. Extensive experiments on various benchmarks and model backbones demonstrate the superiority of CDDS, outperforming state-of-the-art methods by 6.6% to 14.2%.

Despite the exceptional reasoning capabilities of Multimodal Large Language Models (MLLMs), their adaptation into universal embedding models is significantly impeded by task conflict. To address this, we propose TSEmbed, a universal multimodal embedding framework that synergizes Mixture-of-Experts (MoE) with Low-Rank Adaptation (LoRA) to explicitly disentangle conflicting task objectives. Moreover, we introduce Expert-Aware Negative Sampling (EANS), a novel strategy that leverages expert routing distributions as an intrinsic proxy for semantic similarity. By dynamically prioritizing informative hard negatives that share expert activation patterns with the query, EANS effectively sharpens the model's discriminative power and refines embedding boundaries. To ensure training stability, we further devise a two-stage learning paradigm that solidifies expert specialization before optimizing representations via EANS. TSEmbed achieves state-of-the-art performance on both the Massive Multimodal Embedding Benchmark (MMEB) and real-world industrial production datasets, laying a foundation for task-level scaling in universal multimodal embeddings.

While multimodal survival prediction models are increasingly more accurate, their complexity often reduces interpretability, limiting insight into how different data sources influence predictions. To address this, we introduce DIMAFx, an explainable multimodal framework for cancer survival prediction that produces disentangled, interpretable modality-specific and modality-shared representations from histopathology whole-slide images and transcriptomics data. Across multiple cancer cohorts, DIMAFx achieves state-of-the-art performance and improved representation disentanglement. Leveraging its interpretable design and SHapley Additive exPlanations, DIMAFx systematically reveals key multimodal interactions and the biological information encoded in the disentangled representations. In breast cancer survival prediction, the most predictive features contain modality-shared information, including one capturing solid tumor morphology contextualized primarily by late estrogen response, where higher-grade morphology aligned with pathway upregulation and increased risk, consistent with known breast cancer biology. Key modality-specific features capture microenvironmental signals from interacting adipose and stromal morphologies. These results show that multimodal models can overcome the traditional trade-off between performance and explainability, supporting their application in precision medicine.

Tau positron emission tomography supports Alzheimer's disease staging but is difficult to scale because of tracer, scanner, and radiation constraints. Synthesis from structural MRI is therefore attractive, but it is a particularly difficult setting. T1-weighted and FLAIR MRI provide anatomy and disease correlated morphology, but they do not directly measure Tau-PET relevant signal. We introduce SFL-Net, a multi-input synthesis framework that predicts Tau-PET from T1-weighted and FLAIR MRI. SFL-Net factorizes the latent representation into shared, T1-specific, FLAIR-specific, and complementary pathways and preserves anatomical detail through latent structural conditioning rather than direct encoder-decoder connections. We evaluated SFL-Net and baseline models using 605 training and 83 validation subjects from ADNI-3 and OASIS-3 datasets. Evaluation included raw image fidelity, standardized uptake value ratio agreement, high uptake overlap, regional Bland-Altman bias, braak derived stage agreement, non-inferiority sensitivity analysis, and latent component Shapley attribution. SFL-Net performed competitively on both clinically relevant and reconstruction metrics, while also delivering explicit source level auditability that conventional UNet derived models lack.

Accurate interpretation of electrocardiogram (ECG) signals is crucial for diagnosing cardiovascular diseases. Recent multimodal approaches that integrate ECGs with accompanying clinical reports show strong potential, but they still face two main concerns from a modality perspective: (1) intra-modality: existing models process ECGs in a lead-agnostic manner, overlooking spatial-temporal dependencies across leads, which restricts their effectiveness in modeling fine-grained diagnostic patterns; (2) inter-modality: existing methods directly align ECG signals with clinical reports, introducing modality-specific biases due to the free-text nature of the reports. In light of these two issues, we propose CG-DMER, a contrastive-generative framework for disentangled multimodal ECG representation learning, powered by two key designs: (1) Spatial-temporal masked modeling is designed to better capture fine-grained temporal dynamics and inter-lead spatial dependencies by applying masking across both spatial and temporal dimensions and reconstructing the missing information. (2) A representation disentanglement and alignment strategy is designed to mitigate unnecessary noise and modality-specific biases by introducing modality-specific and modality-shared encoders, ensuring a clearer separation between modality-invariant and modality-specific representations. Experiments on three public datasets demonstrate that CG-DMER achieves state-of-the-art performance across diverse downstream tasks.

Multimodal learning aims to capture both shared and private information from multiple modalities. However, existing methods that project all modalities into a single latent space for fusion often overlook the asynchronous, multi-level semantic structure of multimodal data. This oversight induces semantic misalignment and error propagation, thereby degrading representation quality. To address this issue, we propose Cross-Level Co-Representation (CLCR), which explicitly organizes each modality's features into a three-level semantic hierarchy and specifies level-wise constraints for cross-modal interactions. First, a semantic hierarchy encoder aligns shallow, mid, and deep features across modalities, establishing a common basis for interaction. And then, at each level, an Intra-Level Co-Exchange Domain (IntraCED) factorizes features into shared and private subspaces and restricts cross-modal attention to the shared subspace via a learnable token budget. This design ensures that only shared semantics are exchanged and prevents leakage from private channels. To integrate information across levels, the Inter-Level Co-Aggregation Domain (InterCAD) synchronizes semantic scales using learned anchors, selectively fuses the shared representations, and gates private cues to form a compact task representation. We further introduce regularization terms to enforce separation of shared and private features and to minimize cross-level interference. Experiments on six benchmarks spanning emotion recognition, event localization, sentiment analysis, and action recognition show that CLCR achieves strong performance and generalizes well across tasks.

Multimodal Sentiment Analysis (MSA) integrates language, visual, and acoustic modalities to infer human sentiment. Most existing methods either focus on globally shared representations or modality-specific features, while overlooking signals that are shared only by certain modality pairs. This limits the expressiveness and discriminative power of multimodal representations. To address this limitation, we propose a Tri-Subspace Disentanglement (TSD) framework that explicitly factorizes features into three complementary subspaces: a common subspace capturing global consistency, submodally-shared subspaces modeling pairwise cross-modal synergies, and private subspaces preserving modality-specific cues. To keep these subspaces pure and independent, we introduce a decoupling supervisor together with structured regularization losses. We further design a Subspace-Aware Cross-Attention (SACA) fusion module that adaptively models and integrates information from the three subspaces to obtain richer and more robust representations. Experiments on CMU-MOSI and CMU-MOSEI demonstrate that TSD achieves state-of-the-art performance across all key metrics, reaching 0.691 MAE on CMU-MOSI and 54.9% ACC-7 on CMU-MOSEI, and also transfers well to multimodal intent recognition tasks. Ablation studies confirm that tri-subspace disentanglement and SACA jointly enhance the modeling of multi-granular cross-modal sentiment cues.

Multimodal learning seeks to integrate information from heterogeneous sources, where signals may be shared across modalities, specific to individual modalities, or emerge only through their interaction. While self-supervised multimodal contrastive learning has achieved remarkable progress, most existing methods predominantly capture redundant cross-modal signals, often neglecting modality-specific (unique) and interaction-driven (synergistic) information. Recent extensions broaden this perspective, yet they either fail to explicitly model synergistic interactions or learn different information components in an entangled manner, leading to incomplete representations and potential information leakage. We introduce COrAL, a principled framework that explicitly and simultaneously preserves redundant, unique, and synergistic information within multimodal representations. COrAL employs a dual-path architecture with orthogonality constraints to disentangle shared and modality-specific features, ensuring a clean separation of information components. To promote synergy modeling, we introduce asymmetric masking with complementary view-specific patterns, compelling the model to infer cross-modal dependencies rather than rely solely on redundant cues. Extensive experiments on synthetic benchmarks and diverse MultiBench datasets demonstrate that COrAL consistently matches or outperforms state-of-the-art methods while exhibiting low performance variance across runs. These results indicate that explicitly modeling the full spectrum of multimodal information yields more stable, reliable, and comprehensive embeddings.