Nutrient Reasoning

Using food package images to monitor sodium and salt content against South Africa's R214 sodium limits is challenging when screening decisions require product identity, nutrition facts panel evidence, reporting basis, and category-specific thresholds. This study presents a conservative image-based workflow that combines region detection, optical character recognition (OCR), product identity and sodium evidence extraction, R214 category assignment, deterministic threshold comparison, and independent vision language model comparison. The evaluation used 442 packaged food products and 3 929 full package images from a real-world South African food packaging dataset. A YOLO26s small detector generated 4 195 region crops, and strict post-processing produced one sodium evidence row per product. The integrated workflow produced 290 OUTSIDE R214 SCOPE, 139 REVIEW, seven SCREEN-PASS, and six SCREEN-FAIL outcomes. The independent Qwen2.5-VL 7B vision language model workflow produced 387 OUTSIDE R214 SCOPE, 31 REVIEW, twenty SCREEN-PASS, and four SCREEN-FAIL outcomes. The workflows agreed on exact R214 category assignment for 415 of 442 products (93.9%) and on whether the assigned category was within R214 scope for 416 of 442 products (94.1%). Final screening outcome agreement was 307 out of 442 products, or 69.5%. Manual verification on 60 products showed lower strict outcome agreement than regulated status agreement, while all manual INSUFFICIENT DATA cases were kept out of SCREEN-PASS and SCREEN-FAIL by both automated workflows. The findings show that conservative image-based screening can organise package evidence, identify clear cases, and assign uncertain cases to REVIEW rather than forcing SCREEN-PASS or SCREEN-FAIL decisions.

An embodied kitchen assistant must do more than recognize food in isolated frames. It must track ingredient states over time and integrate visual observations with recipe and nutritional knowledge to support constraint-aware decision-making. We formalize this capability as \emph{Embodied Nutrition Management}: perceiving nutrition-relevant events, maintaining a persistent food state, and using it for knowledge-grounded planning. Existing benchmarks evaluate static food understanding or embodied cooking actions, but do not measure whether an agent can continuously update and use nutrition-relevant states in dynamic kitchens. To fill this gap, we introduce \textbf{NutriBench-Kitchen}, a benchmark containing 1,500 manually verified question--answer pairs from 160 cooking videos. It covers five task families: Ingredient Entry, Memory Management, Recipe Query, Long-Term Planning, and Short-Term Planning, spanning food-state construction, maintenance, knowledge retrieval, and decision-making across different planning horizons. Evaluations of proprietary and open-source large vision-language models reveal a substantial gap from human performance, particularly in quantitative ingredient estimation, long-term state tracking, and reasoning under interacting constraints. We further introduce \textbf{Nutri-Vgent}, a diagnostic long-video agent with separate episodic, food-state, and recipe memories. Its consistent improvements demonstrate the value of explicit state representations and structured memory for nutrition management. Together, NutriBench-Kitchen and Nutri-Vgent provide a testbed for studying persistent state tracking and knowledge-grounded reasoning in dynamic kitchens. Code is available at https://github.com/V1ol1n/NutriBench-Kitchen.

Several studies have evaluated the ability of Large Language Models (LLMs) for meal planning, yielding positive outcomes. These models can process natural language inputs and leverage learned knowledge from their pretraining to generate meal plans. In this work, we investigate the ability of LLMs to analyze the suitability of given recipes for diabetes. The primary challenge for LLMs is to retrieve relevant dietary guidelines for diabetes, decompose recipes into ingredients and cooking methods, and apply these guidelines to determine the recipe's suitability. To study these challenges, we employ three kinds of prompts namely, (i) Direct Query Prompt (ii) Context-Guided Prompt, and (iii) Exemplary Context Prompt that incorporate different levels of diabetes dietary guidelines from medical sources. We introduce a benchmark dataset curated for this investigation consisting of 7607 recipes that include 3807 recipes suitable for diabetes and 3800 recipes not suitable for diabetes. Our results demonstrate that most LLMs are cautious in predicting recipes as suitable to prevent detrimental outcomes. Further, the models that can reason using the dietary guidelines performed better in predicting the suitability of recipes for diabetes. Overall, Mistral-7B and Llama 70B showed superior performance to their counterparts.

AI agents can accelerate nutrition research, but their analyses inherit the identity, semantic, and release ambiguities of the underlying data. We present Nutrition Data Service (NDS), source-preserving infrastructure that operationalizes FAIR for automated use: description resolution makes release-specific records findable; typed crosswalks connect independently released resources; machine-readable interfaces expose versioned sources and crosswalks, supporting replayable and auditable analyses. On food-description benchmarks, NDS outperforms the best published language-model result on NutriBench. External and blinded crosswalk evaluations show that its typed contract favors defensible links and rejects unsupported mappings. In a person-level glycemic-index analysis, pinned NDS inputs produce identical outputs across models and repeated runs, while open-web reconstruction remains unstable. Together, these results show that agent-mediated nutrition research requires a new infrastructure that makes data identity, search, and crosswalk policy explicit.

Image based dietary assessment offers a scalable alternative to self reported food diaries, yet fine-grained food recognition remains challenging due to high intra-class variability and visually similar dishes. This study presents OliveGemma, a vision language model for recognising and reasoning about Mediterranean and European cuisine. Built on the open-weight PaliGemma-2-3B architecture, OliveGemma is fine-tuned with LoRA on a unified corpus of 17,340 images from three European research project datasets (MedGR, ODIN, and VIPPSTAR), reconciled into a vocabulary of 216 composed dish categories and paired with 102,642 instruction style question-answer items covering dish recognition, likely and visible ingredients, class boundary discrimination, visual evidence and overall visual food understanding. Under a 3-fold cross-validation scheme, OliveGemma achieves a top-1 accuracy of 92.96% +/- 0.91%, exceeding the strongest CNN baseline (DenseNet-121) by 7.31% and outperforming zero-shot frontier models with exact instructions and bounded classes including Gemini Flash 3 and 3.5, GPT-5.4 Mini, and Claude Haiku 4.6 by 8%, 46%, and 64% respectively. Furthermore, OliveGemma demonstrates competitive performance on Top-3 and Top-5 accuracy, being second best across CNNs and frontier models, surpassed only by DenseNet-121. In addition, OliveGemma achieves 90.79% +/- 1.3% Exact-Set on the likely ingredients of the food categories. These results demonstrate that PEFT adaptation of a small VLM can surpass substantially larger proprietary models on specialised food recognition. The model is publicly available at https://huggingface.co/JamesZar/OliveGemma-3B and the experiments and results can be found at https://github.com/tsiokris/OliveGemma.

The ASNR-MICCAI BraTS Local Synthesis (Inpainting) task asks for the anatomically plausible completion of healthy brain tissue within a masked region of a T1-weighted MRI, providing a tumor-free anatomical reference for downstream analysis. As the task is scored by distortion metrics (SSIM, PSNR, MSE), we build a deterministic regression model and focus on giving it inductive biases tailored to inpainting. Our network follows the U-DiT principle of performing self-attention on a downsampled token grid: a volumetric encoder-decoder imports long-range context through a downsampled global self-attention block with three-dimensional rotary position embeddings, while convolutions and skip connections preserve high-frequency detail. Two ideas drive our results. First, we constrain the attention so that occluded ("void") tokens attend only to known-healthy tokens of the same volume, with a learned bias toward each query's contralateral homologue, forcing the completion to be inferred from observed anatomy rather than from other unknown regions. Second, we add a contralateral-symmetry input that supplies the mirrored healthy hemisphere as a patient-specific prior; since the brain is approximately bilaterally symmetric and lesions are typically unilateral, this prior improves the distortion metrics at matched structural similarity. On the official BraTS-2026 validation leaderboard our submission reaches a mean healthy-region SSIM of $0.864$, PSNR of $24.7$,dB and MSE of $4.6{\times}10^{-3}$ over $219$ cases. We further analyse the residual smoothness inherent to distortion-optimal regression and discuss its implications for anatomical realism.

Computational nutrition needs precise ingredient data, but current databases are incomplete, inconsistent, and built for human reference rather than automated reasoning. LLMs could help fill these gaps, but single-pass outputs are unreliable and can introduce silent errors into downstream computation. We present a quality-controlled LLM pipeline for ingredient data acquisition that combines robust statistical estimation, domain-specific invariant checks, and a web-fetch fallback. An illustrative Heap's Law fit to 233 recipes suggests that unique-ingredient growth is sub-linear and front-loaded: the projected ratio of unique ingredients to recipes falls from 1.74 at 100 recipes to 0.19 at 5,000. For each ingredient attribute, repeated LLM queries are treated as samples from a model-induced answer distribution, and we apply robust point estimators and normalised confidence scores across numerical, Boolean, multiple-choice, open categorical, and optional integer types. An invariant guard layer enforces nutritional and logical self-consistency within each ingredient record. Minor numeric inconsistencies are reconciled via a linear program that minimises worst-case percentage deviation while preserving semantic zeros, and major violations are escalated to web-evidence-grounded repair, then human review only if that fails. On a curated 30-ingredient reference set, the pipeline achieves 98.4% exact match on nutrient flags and cuts median absolute percentage error on nutrient ratios from 31.9% for the median-aggregated baseline to 10.1%, a reduction of 21.8 percentage points, at an API cost of about $1 per ingredient. This frames LLM-assisted database construction as a controlled data-engineering workflow that makes uncertainty operational rather than discarding it.

The dominance of traditional rule-based methods in autonomous driving has gradually been replaced by learning-based approaches. While learning-based planners have achieved considerable success in passenger vehicles, their performance on heavy-duty trucks, particularly modern distributed electric-drive trucks (DETs), remains largely unexplored. To facilitate research and application of learning-based planners in DETs, this letter presents the first high-fidelity benchmark, called nuTruck, designed to support large-scale neural network training and closed-loop evaluation. Given the complex dynamics and high rollover susceptibility of DETs, we first incorporate a highly accurate nonlinear truck dynamical model into the simulation, which enables independent driving and steering of all wheels and captures dynamic load transfer caused by acceleration, deceleration, and cornering, thereby allowing quantitative assessment of rollover risk in closed-loop simulation. Second, we adapt several rule-based and learning-based planners as baselines for DETs and evaluate their performance in closed-loop simulation. Finally, using real-world driving scenarios from the nuPlan dataset, we conduct extensive closed-loop evaluations, analyzing not only conventional collision-free planning performance, but also the dynamical safety of the planned trajectories. The proposed nuTruck benchmark is expected to serve as a new standard for fair and realistic evaluation of autonomous driving planners on DETs.

Multimodal Large Language Models (MLLMs) are increasingly used for dietary assessment from meal images, where retrieval-augmented grounding was shown to sharpen nutrition estimates. However, we find this premise no longer holds for current MLLMs. A modern MLLM's direct estimate now matches or surpasses the full retrieval pipeline. This raises a question: if retrieval no longer improves the overall estimate, can it still deliver the two things clinicians value, accurate portions and a traceable, item-by-item record? We pursue this while preserving what matters for clinical adoption: minimal user burden (a single, unannotated meal image), explainability (an auditable record), and privacy (locally hosted inference). We introduce Open-KNEAD, a knowledge-grounded agentic framework for meal nutrition estimation that is training-free and locally deployable. Each decomposed food item is grounded to a Food and Nutrient Database for Dietary Studies (FNDDS) code via selective, nutrient-aware retrieval, composing an auditable per-item record. Across two open MLLM families and three cuisines, Open-KNEAD improves portion estimates over both prior grounding methods and direct estimation in most backbone-dataset settings. An agent-internal recipe-prior step further recovers the invisible cooking-added energy that biases estimates on non-US cuisine. The advantage is largest on the dietitian-verified ACETADA dataset, where the local open agent surpasses the direct portion estimates of two frontier closed models by roughly $30\%$ and $53\%$, all while keeping every meal image on local hardware. We release the Open-KNEAD framework and its agent-ready FNDDS knowledge base.

The rapid integration of Large Vision-Language Models (VLMs) into critical infrastructure promises to revolutionize personalized healthcare and dietary management. However, in the domain of food systems, autonomous agents face a unique and persistent challenge: the "Systemic Information Asymmetry" between visual appearance and intrinsic nutritional composition. Existing benchmarks primarily focus on coarse-grained classification tasks, such as food category recognition, which fail to evaluate the intricate reasoning chain required for real-world dietary management -- specifically, the ability to traverse from identifying hidden ingredients to estimating physical mass, and finally synthesizing safety-critical medical advice. In this paper, we introduce OmniFood-Bench, a comprehensive benchmark constructed from the MM-Food-100K dataset. Unlike previous works, OmniFood-Bench evaluates VLMs across three progressive capabilities: Basic Perception (Ingredients & Cooking Methods), Quantitative Reasoning (Portion Size & Nutritional Profiling), and Safety-Critical Advisory (Disease-Specific Recommendations). We evaluate six state-of-the-art VLMs, including gpt-5.1, gemini-3-flash, and qwen3-vl-8B. Our extensive experiments reveal a startling "Semantic-Physical Gap": while models achieve near-human accuracy in naming dishes, they exhibit catastrophic failure in mass estimation and frequently hallucinate benign advice for high-risk diabetic profiles. This work establishes a rigorous standard for trustworthiness in autonomous agents deployed for public health. The code and datasets are available in: https://anonymous.4open.science/r/OmniFood-Bench-7D0B

Knowledge Distillation (KD) is widely used to obtain compact models for efficient inference in resource-constrained environments. Yet the computational overhead of the distillation process itself is often overlooked, raising the question of whether a better student model can be obtained with less data and less compute via data pruning. However, existing data pruning methods are not designed for KD: some introduce substantial overhead, such as obtaining training dynamics through retraining, while others rely on heuristic selection rules that fail to capture what KD actually requires, often resulting in suboptimal subsets. To address these issues, we propose IF-Beta, an efficient data pruning framework that combines influence functions with a learnable sampling policy. Empirically, we first demonstrate that influence functions can serve as an effective and efficient estimator of sample impact in KD settings, where only a pretrained teacher is available. Building on this, our sampling policy is specifically parameterized by a Beta distribution, whose highly flexible two-parameter family allows the policy to adapt to diverse pruning regimes rather than being tied to fixed heuristic forms. Next, we formulate KD pruning as optimizing this policy through a bilevel objective, where the inner loop operates in the teacher feature space with a KD-aligned objective, enabling fast proxy training, while the outer loop updates the policy parameters to maximize distillation performance. This design ensures that IF-Beta is both computationally efficient and inherently aligned with the goals of KD. Extensive experiments on CIFAR-10/100 and ImageNet show that IF-Beta consistently outperforms other baselines across a wide range of pruning ratios. Remarkably, IF-Beta enables students trained on less data and less compute to surpass the performance of students distilled on the full dataset.

Food images often contain several visible ingredients, so assigning one dish label to an entire image hides important visual structure. This work studies ingredient-level semantic segmentation on FoodSeg103, where the model predicts an ingredient class for each pixel. Two SegFormer variants were fine-tuned and evaluated under a controlled setup: SegFormer-B0 as the smaller baseline model and SegFormer-B1 as the larger final model. Both models use ImageNet-pretrained MiT backbones with newly initialized 104-class output layers. On the held-out FoodSeg103 test split of 2,135 images, B0 achieved 0.7709 pixel accuracy and 0.2521 mean IoU, while B1 achieved 0.7929 pixel accuracy and 0.3204 mean IoU. B1 improved every saved test metric, including a +0.0683 absolute gain in mean IoU. The system also converts predicted masks into visible ingredient-area percentages, giving a simple visual composition summary of the predicted meal. This summary can serve as a first-pass nutrition-awareness cue by providing a visual alternative to detailed food tracking similar to plate-based meal guidance, but it is not a direct estimate of calories, macronutrients, food mass, volume, density, or true portion size.

Unhealthy dietary behavior continues to be a persistent public health issue in the United States, exacerbated by recommendation systems that prioritize user preference without considering nutritional health. The Multi-Objective Personalized Interpretable Health-aware Food Recommendation System (MOPI-HFRS), from which this work extends, addresses this by jointly optimizing preference, health, and diversity through Pareto-based optimization. However, this approach relies on static, per-step tradeoff solutions that fail to capture the sequential nature of dietary decision-making. We introduce MORL-A2C, a sequential decision-making extension to MOPI-HFRS targeting the health-preference axis. Leveraging frozen GNN embeddings, MORL-A2C formulates recommendation as a K-step reranking problem using an Advantage Actor-Critic algorithm with a scalarized relevance/health reward. The policy is warm-started via behavior cloning against a dot-product ranker derived from frozen embeddings. We also identify and correct a non-trivial bug in the MOPI-HFRS evaluation pipeline that understated baseline performance; all results are reported against the corrected baseline. On the macro-nutrient benchmark, MORL-A2C achieves a modest reduction in ranking quality (Recall@20: 25.64% to 23.61%, NDCG@20: 23.52% to 20.64%) in exchange for a substantial improvement in health alignment (H-Score@20: 46.05% to 69.57%), with consistent trends on the full-nutrient benchmark. These findings validate that policy-driven sequential optimization can effectively navigate the health-preference trade-off in multi-objective food recommendation.

Postprandial hyperglycemia is a key risk factor for metabolic disorders; however, existing dietary guidance is often static, impractical, and insufficiently personalized, providing recommendations that are difficult to follow or not impactful. While recent advances leverage continuous glucose monitoring (CGM) and machine learning to predict glycemic responses, these approaches are largely predictive and lack actionable guidance. Moreover, recommendation systems are often misaligned with user goals and require extensive input. We present MetaPlate, a counterfactual explanation (CF) guided, context-aware decision-support framework that generates personalized meal recommendations to mitigate postprandial glucose excursions in healthy adults. MetaPlate integrates multimodal data, including CGM readings, wearable-derived physiological signals, and user-provided meal inputs from $25$ individuals to model pre-meal context. A machine learning model predicts glucose response, while a CF optimization module adjusts meal composition modifying macronutrient amounts to maintain glucose levels within a target range ($\leq 140$ mg/dL). An LLM-based retrieval-augmented generation (RAG) layer enhances interpretability by producing human-readable recommendations using constrained search of the USDA food database. We evaluate MetaPlate via a structured expert-in-the-loop assessment with registered dietitians (RDs), comparing performance before and after prompt refinement. Results show improvements in meal realism, portion suitability, and recommendation likelihood, with expert feedback indicating a shift from clinically implausible outputs to actionable, contextually appropriate recommendations. Our findings emphasize the importance of domain knowledge and structured constraints in LLM-driven systems and highlight the potential of MetaPlate as a real-time personalized dietary decision-support tool.

Comprehensive estimation of dietary micronutrients from food images could improve clinical nutrition care, but training such models requires large multimodal datasets linking diverse foods to complete nutrient profiles. We first show that existing multimodal large language models (MLLMs), including leading proprietary models, are unreliable for this task. Across five model families and four independent evaluation benchmarks (ASA24, SNAPMe, FNDDS, and NutriBench), models frequently abstained or returned statistically implausible values. To address this gap without costly expert annotation, we repurposed a decade of population-scale 24-hour dietary recalls as structured prompts for text-to-image generation. This pipeline produced a synthetic corpus of about 1.1 million image-description-nutrient triplets, each pairing a generated food image with a complete 65-nutrient label. To our knowledge, this is the largest synthetic food-image corpus with comprehensive micronutrient annotation planned for public release upon publication. Fine-tuning Qwen3-VL (2B/4B/8B/30B) and GLM-4.6V-Flash on this corpus yielded NutriMLLM, the first family of vision-language models specialized for comprehensive dietary micronutrient estimation. We evaluate these models with a four-component framework that separately measures abstention, hallucination, overall usability, and per-nutrient numerical accuracy. On real food images, every NutriMLLM variant achieved near-complete coverage across all 65 nutrients, and the largest variant matched or exceeded proprietary baselines (GPT-5, Gemini 3, and Claude Sonnet 4.5) in accuracy on most nutrients. These results show that recall-driven synthetic supervision can make image-based comprehensive micronutrient estimation a tractable engineering problem and support dietary assessment, personalized nutrition guidance, and population-scale micronutrient surveillance.

Recent studies have explored Vision-Language Models (VLMs) for food analysis. However, most existing methods rely primarily on supervised fine-tuning (SFT), which often limits reasoning and generalization capabilities. Moreover, high-quality large-scale nutritional annotations remain scarce. To address these issues, we introduce CalorieBench-80K, a large-scale benchmark with curated calorie labels and dietary advice annotations. To the best of our knowledge, it is the first food image benchmark to incorporate Chain-of-Thought (CoT) annotations for calorie reasoning. We also propose Food-R1, a unified food VLM trained in a multi-task learning paradigm to equip the model with broad capabilities. Food-R1 undergoes CoT-based cold-start instruction tuning, followed by reinforcement fine-tuning (RFT) using Group Relative Policy Optimization (GRPO) to improve reasoning and performance. Experiments on CalorieBench-80K and representative benchmarks show that Food-R1 consistently outperforms strong baselines across food-related tasks. The code, model weights, and benchmark annotations are available at the project repository.

Can a visually plausible food mesh be trusted to estimate the volume of consumed food? \method investigates this question using selected paired before- and after-consumption states from the MetaFood CVPR 2026 Continuous 3D Reconstruction While Eating Challenge. The submitted workflow follows a curated reconstruction protocol: SAM3 segments the food and plate regions; Hunyuan3D/SAM3D generates a dimensionless food mesh; the plate diameter provides the metric scale; the plate geometry is removed in Blender; and the remaining mesh is hole-filled, made watertight, and integrated to estimate volume. MoGe-2 is used only as an auxiliary cue for initial dish-diameter estimation when direct plate measurement is uncertain; it is not the primary scale source for the reported challenge result. \method ranks first, with an average Chamfer distance of 8.31 across 34 meshes using rigid ICP without scale correction. On 17 before- and after-pairs, it achieves 33.87% state-level volume MAPE and zero monotonicity violations, while consumed-volume MAPE remains 53.74%. The results show that surface reconstruction, metric scale, controlled mesh cleanup, watertight volume integration, and physical depletion consistency should be evaluated separately for dietary assessment. Source code and evaluation scripts will be available at \href{https://github.com/GCVCG/PerBite-CVPR-MetaFood-2026}{github.com/GCVCG/PerBite-CVPR-MetaFood-2026}.

As AI-powered compliance monitoring becomes increasingly important in public governance and industrial safety, the ability to provide verifiable evidence and traceable accountability signals is essential. However, existing video anomaly detection datasets focus on event-level binary classification, lacking the rule-driven, explainable analysis required for real-world compliance scenarios. We introduce FoodMonitor, a benchmark for explainable compliance analysis in commercial kitchen surveillance. FoodMonitor comprises 477 video clips with 3,307 violation annotations across a dual-channel design covering both person-level and environment-level violations. Each annotation specifies which rule was violated, what non-compliant behavior occurred, and who committed it with frame-level bounding boxes. We establish a unified evaluation protocol with a two-stage matching mechanism that separately assesses spatial localization and semantic understanding, along with a composite metric ($C_{\text{score}}$) that balances environment and person detection performance. Systematic evaluation of several state-of-the-art multimodal large language models reveals that the best-performing model achieves only 0.360 $C_{\text{score}}$, with spatial localization and fine-grained rule understanding emerging as the primary bottlenecks. Our analysis identifies two distinct failure modes: localization-dominated errors and semantics-dominated errors, providing diagnostic insights for future model development.

We present Epicure, a family of three sibling skip-gram ingredient embeddings retrained from scratch on a multilingual recipe corpus. We aggregate 4.14M recipes from 11 sources spanning seven languages, English, Chinese, Russian, Vietnamese, Spanish, Turkish, Indonesian, German, and Indian-English, and normalise the raw ingredient strings to 1,790 canonical entries via an LLM-augmented pipeline. A 203,508-edge ingredient-ingredient NPMI graph and an 80,019-edge typed FlavorDB ingredient-compound graph, 2,247 typed compound nodes across 15 categories, seed three Metapath2Vec variants that share architecture and hyperparameters and differ only in the random-walk schema: Cooc walks the co-occurrence graph only, Chem walks the typed compound metapaths only, and Core blends both via injected ingredient-ingredient walks at controlled mixing, placing each model at a distinct point on the chemistry-vs-recipe-context spectrum.

In biomedical Subgroup Discovery, practitioners are interested in discovering interpretable and homogeneous subgroups within a group of patients. In this paper, assuming that healthy subjects (i.e., controls) share common but irrelevant factors of variation with the patients, we motivate and develop a Contrastive Subgroup Discovery method, entitled Deep UCSL. By contrasting patients with controls, Deep UCSL identifies subgroups driven solely by pathological factors, ignoring common variability shared with healthy subjects. Our framework employs a deep feature extractor to learn a discriminative representation space. Mathematically, we derive a novel loss based on the conditional joint likelihood of latent clusters and patient/control labels, optimized via an Expectation-Maximization strategy alternating between subgroup inference and feature encoder updates. A regularization term further encourages representations to capture disease-specific variability while ignoring variability shared with controls. Compared to previous related works, our approach quantitatively improves the quality of the estimated subgroups, as demonstrated on a MNIST example and four distinct real medical imaging datasets. Code and datasets are available at: https://github.com/rlouiset/deep_ucsl.

Make America Healthy Again (MAHA) is a national health movement that encompasses a striking mix of beliefs, from broadly accepted concerns about good diet and exercise to controversial takes on organic and genetically modified food, childhood vaccination, science, and institutions. Various influencers and promoters of the MAHA movement on social media are scattered throughout the online space. Investigating the structure, discourse, and contagion of MAHA beliefs requires large-scale fine-grained digital footprints. Constructing structured data covering different MAHA themes from vast unstructured social media data is challenging. We introduce a Reddit dataset that spans six years (2020-2025), comprising 19.4M posts from 4M users. Containing the natural and thematic context of 12 MAHA-aligned beliefs, this dataset offers researchers from various domains the opportunity to study the dynamics of the MAHA movement, its structural and functional components, and the linguistic and behavioral patterns of its proponents.

Large language model (LLM)-based simulations of clinical patients are increasingly used for research and training, yet their validity requires persona stability: coherent maintenance of an assigned psychological profile across and within conversations. We evaluate this prerequisite using eating disorder personas grounded in five published case vignettes, a dual-assessment framework (self-report + independent observer ratings), and validated psychometric instruments (EDE-Q) with known ground-truth scores. Across six LLMs and two experiments (between-conversation stability (Exp. I) and within-conversation stability (Exp. II)), we find that LLMs are paradoxically too stable and too inaccurate: variability is negligible, yet all models systematically overshoot ground-truth severity by 12-30% of the scale range (0.7-1.8 points on a 0-6 scale). The mechanism is selective stereotyping: models differentiate cases on behavioural items (dietary restraint) but maximise cognitive-affective items (body dissatisfaction, weight preoccupation) at ceiling regardless of case severity. Additional conversational context does not improve accuracy; it compounds the overshoot. LLMs can portray severe eating pathology but lack a representation of moderate clinical presentations, a "missing middle".

Diet quality is a leading determinant of chronic disease risk. Advances in artificial intelligence (AI) have enabled food recommendation systems to adapt suggestions to user preferences and health goals. However, most current systems rely on loosely curated food databases and provide limited connection to a validated index. In this study, we propose a Healthy Eating Index (HEI) informed retrieval-augmented generation (RAG) framework that combines standardized nutrition databases with large language models (LLMs) for personalized food recommendations. Our proposed method anchors retrieval in the National Health and Nutrition Examination Survey (NHANES) and the Food Patterns Equivalents Database (FPED). A food-level embedding space is constructed from FPED-derived textual descriptions. For each entity, the system computes baseline HEI scores, retrieves candidate foods for intake recommendations, and estimates the HEI impact of simple substitutions or additions. A constrained RAG pipeline instantiated with a pretrained OpenAI LLM generates personalized recommendations and sources based on nutrient profiles and HEI contributions. The simulation results showed a mean HEI improvement of 6.45, with the proportion of users HEI over 50 increasing from 45.12 to 61.26. Quantile analysis revealed consistent improved shifts across the HEI distribution. Our findings suggest that the proposed LLM-RAG-based AI systems can support more precise, explainable, and personalized nutrition guidance to improve diet quality.

Clinical dietary assessment can generate detailed but high-dimensional nutrient and food-group information that is difficult to translate quickly into counselling priorities. This paper proposes an explainable unsupervised-to-supervised machine learning framework for discovering, reproducing and interpreting dietary patterns using public UK National Diet and Nutrition Survey data. Adult participants aged 19 years and above from NDNS Years 12-15 were represented using 25 energy-adjusted nutrient and food-group features. K-means, Gaussian Mixture Models and Agglomerative Clustering were compared across k = 2-8, with stability and dietetic interpretability used alongside internal validation metrics. The selected K-means k = 4 solution identified four interpretable dietary patterns: high fat/meat and sodium, higher fibre fruit-vegetable micronutrient, high free-sugar snacks and sugary drinks, and dairy/cereal calcium-rich saturated-fat. A supervised surrogate classifier reproduced held-out cluster membership with high test performance (macro-F1 = 0.963), but was interpreted only as an explanatory surrogate rather than as an independent clinical prediction model. SHAP analysis linked predictions to dietetically meaningful drivers, suggesting potential value for dietitian-in-the-loop assessment, counselling prioritisation and follow-up monitoring.

Doubly Robust (DR) estimation of treatment effect relies on an untestable assumption that is the absence of unobserved confounding. This assumption is par- ticularly problematic in the context of healthcare research, where variables like pre- scription refill rates serve as proxies for unobserved behaviors such as medication adherence. These proxy variables are often endogenous, exhibiting correlation with the regression error term due to unmeasured confounding or measurement error. We propose a copula-corrected doubly robust estimator that addresses endogeneity in both the treatment and outcome models without requiring instrumental variables. Gaussian copulas model the joint distribution of endogenous covariates and the error term, enabling consistent estimation while preserving the doubly robust property that requires correct specification of either the treatment or outcome model, not both. Monte Carlo simulations demonstrate that naive DR estimation exhibits substantial bias under endogeneity, whereas our corrected estimator recovers unbiased treatment effects across different data-generating processes. We apply our method to examine the effect of nutritional counseling on blood pressure using the National Health and Nutrition Examination Survey (NHANES) data. Naive DR estimation suggests counseling is associated with increased blood pressure. After copula correction, this effect becomes statistically insignificant, consistent with literature showing modest effects of nutri- Counseling in reducing blood pressure. Our methodology provides researchers with a practical tool for obtaining treatment effects in the presence of endogeneity.

Public opinion towards the Free Nutritious Meal Program (MBG) on YouTube social media reflects diverse community responses. This study applies the Long Short-Term Memory (LSTM) method to classify sentiments from 7,733 YouTube comments. The results show that the LSTM model achieves 89% accuracy, with strong performance on negative sentiment (F1-score 0.94) but weaker performance on positive sentiment (F1-score 0.55) due to class imbalance, as negative data account for 87.7% of the dataset. These findings confirm the effectiveness of LSTM for sentiment analysis of Indonesian text while highlighting the challenge of imbalanced data. This research contributes to social media-based public policy evaluation

Accurate nutrient estimation from unstructured recipe text is an important yet challenging problem in dietary monitoring, due to ambiguous ingredient terminology and highly variable quantity expressions. We systematically evaluate models spanning a wide range of representational capacity, from lexical matching methods (TF-IDF with Ridge Regression), to deep semantic encoders (DeBERTa-v3), to generative reasoning with large language models (LLMs). Under the strict tolerance criteria defined by EU Regulation 1169/2011, our empirical results reveal a clear trade-off between predictive accuracy and computational efficiency. The TF-IDF baseline achieves moderate nutrient estimation performance with near-instantaneous inference, whereas the DeBERTa-v3 encoder performs poorly under task-specific data scarcity. In contrast, few-shot LLM inference (e.g., Gemini 2.5 Flash) and a hybrid LLM refinement pipeline (TF-IDF combined with Gemini 2.5 Flash) deliver the highest validation accuracy across all nutrient categories. These improvements likely arise from the ability of LLMs to leverage pre-trained world knowledge to resolve ambiguous terminology and normalize non-standard units, which remain difficult for purely lexical approaches. However, these gains come at the cost of substantially higher inference latency, highlighting a practical deployment trade-off between real-time efficiency and nutritional precision in dietary monitoring systems.