Transfer Learning

Existing prompt-based fine-tuning methods typically learn task-specific prompts independently, imposing significant computing and storage overhead at scale when deploying multiple clinical natural language processing (NLP) systems. We present a multitask prompt distillation and decomposition framework that learns a single shared metaprompt from 21 diverse clinical source tasks and adapts it to unseen target tasks with fewer than 0.05% trainable parameters. Evaluated across five clinical NLP task types (named entity recognition, relation extraction, question answering, natural language inference, and summarization) on 10 held-out target datasets using three backbone models (LLaMA 3.1 8B, Meditron3 8B, gpt-oss 20B), our framework consistently outperforms LoRA by 1.51.7% despite using orders of magnitude fewer parameters, and exceeds single-task prompt tuning by 6.16.6%. The gpt-oss 20B model achieves the highest overall performance, particularly on clinical reasoning tasks. The strong zero- and few-shot performance demonstrates better transferability of the shared prompt representation.

Cross-city transfer improves prediction in label-scarce cities by leveraging labeled data from other cities, but it becomes challenging when cities adopt incompatible partitions and no ground-truth region correspondences exist. Existing approaches either rely on heuristic region matching, which is often sensitive to anchor choices, or perform distribution-level alignment that leaves correspondences implicit and can be unstable under strong heterogeneity. We propose SCOT, a cross-city representation learning framework that learns explicit soft correspondences between unequal region sets via Sinkhorn-based entropic optimal transport. SCOT further sharpens transferable structure with an OT-weighted contrastive objective and stabilizes optimization through a cycle-style reconstruction regularizer. For multi-source transfer, SCOT aligns each source and the target to a shared prototype hub using balanced entropic transport guided by a target-induced prototype prior. Across real-world cities and tasks, SCOT consistently improves transfer accuracy and robustness, while the learned transport couplings and hub assignments provide interpretable diagnostics of alignment quality.

Graphs are a central representation in biomedical research, capturing molecular interaction networks, gene regulatory circuits, cell--cell communication maps, and knowledge graphs. Despite their importance, currently there is not a broadly reusable foundation model available for graph analysis comparable to those that have transformed language and vision. Existing graph neural networks are typically trained on a single dataset and learn representations specific only to that graph's node features, topology, and label space, limiting their ability to transfer across domains. This lack of generalization is particularly problematic in biology and medicine, where networks vary substantially across cohorts, assays, and institutions. Here we introduce a graph foundation model designed to learn transferable structural representations that are not specific to specific node identities or feature schemes. Our approach leverages feature-agnostic graph properties, including degree statistics, centrality measures, community structure indicators, and diffusion-based signatures, and encodes them as structural prompts. These prompts are integrated with a message-passing backbone to embed diverse graphs into a shared representation space. The model is pretrained once on heterogeneous graphs and subsequently reused on unseen datasets with minimal adaptation. Across multiple benchmarks, our pretrained model matches or exceeds strong supervised baselines while demonstrating superior zero-shot and few-shot generalization on held-out graphs. On the SagePPI benchmark, supervised fine-tuning of the pretrained backbone achieves a mean ROC-AUC of 95.5%, a gain of 21.8% over the best supervised message-passing baseline. The proposed technique thus provides a unique approach toward reusable, foundation-scale models for graph-structured data in biomedical and network science applications.

We investigate whether post-trained capabilities can be transferred across models without retraining, with a focus on transfer across different model scales. We propose the Master Key Hypothesis, which states that model capabilities correspond to directions in a low-dimensional latent subspace that induce specific behaviors and are transferable across models through linear alignment. Based on this hypothesis, we introduce UNLOCK, a training-free and label-free framework that extracts a capability direction by contrasting activations between capability-present and capability-absent Source variants, aligns it with a Target model through a low-rank linear transformation, and applies it at inference time to elicit the behavior. Experiments on reasoning behaviors, including Chain-of-Thought (CoT) and mathematical reasoning, demonstrate substantial improvements across model scales without training. For example, transferring CoT reasoning from Qwen1.5-14B to Qwen1.5-7B yields an accuracy gain of 12.1% on MATH, and transferring a mathematical reasoning direction from Qwen3-4B-Base to Qwen3-14B-Base improves AGIEval Math accuracy from 61.1% to 71.3%, surpassing the 67.8% achieved by the 14B post-trained model. Our analysis shows that the success of transfer depends on the capabilities learned during pre-training, and that our intervention amplifies latent capabilities by sharpening the output distribution toward successful reasoning trajectories.

While deep learning has achieved remarkable success in medical imaging, the "black-box" nature of backpropagation-based models remains a significant barrier to clinical adoption. To bridge this gap, we propose Aristotelian Rapid Object Modeling (A-ROM), a framework built upon the Platonic Representation Hypothesis (PRH). This hypothesis posits that models trained on vast, diverse datasets converge toward a universal and objective representation of reality. By leveraging the generalizable metric space of pretrained Vision Transformers (ViTs), A-ROM enables the rapid modeling of novel medical concepts without the computational burden or opacity of further gradient-based fine-tuning. We replace traditional, opaque decision layers with a human-readable concept dictionary and a k-Nearest Neighbors (kNN) classifier to ensure the model's logic remains interpretable. Experiments on the MedMNIST v2 suite demonstrate that A-ROM delivers performance competitive with standard benchmarks while providing a simple and scalable, "few-shot" solution that meets the rigorous transparency demands of modern clinical environments.

Detecting cyberattacks in photovoltaic (PV) monitoring and MPPT control signals requires models that are robust to bias, drift, and transient spikes, yet lightweight enough for resource-constrained edge controllers. While deep learning outperforms traditional physics-based diagnostics and handcrafted features, standard fine-tuning is computationally prohibitive for edge devices. Furthermore, existing Parameter-Efficient Fine-Tuning (PEFT) methods typically apply uniform adaptation or rely on expensive architectural searches, lacking the flexibility to adhere to strict hardware budgets. To bridge this gap, we propose Constraint-Driven Warm-Freeze (CDWF), a budget-aware adaptation framework. CDWF leverages a brief warm-start phase to quantify gradient-based block importance, then solves a constrained optimization problem to dynamically allocate full trainability to high-impact blocks while efficiently adapting the remaining blocks via Low-Rank Adaptation (LoRA). We evaluate CDWF on standard vision benchmarks (CIFAR-10/100) and a novel PV cyberattack dataset, transferring from bias pretraining to drift and spike detection. The experiments demonstrate that CDWF retains 90 to 99% of full fine-tuning performance while reducing trainable parameters by up to 120x. These results establish CDWF as an effective, importance-guided solution for reliable transfer learning under tight edge constraints.

Frozen pretrained image representations are widely used for transfer learning: a backbone is kept fixed, feature vectors are extracted, and a lightweight classifier is trained on top. This pipeline usually feeds the full feature vector to the classifier, even when the target task has far fewer classes than the pretraining task. We revisit a classical alternative: supervised dimensionality reduction with Linear Discriminant Analysis (LDA) before linear probing. We evaluate ten dimensionality-reduction strategies on frozen features from six backbones -- ResNet-18, ResNet-50, MobileNetV3-Small, EfficientNet-B0, ViT-B/16, and DINOv2-ViT-S/14 -- across CIFAR-100, Tiny ImageNet, and CUB-200-2011. Under a fixed logistic-regression protocol, LDA improves accuracy over full features in 11 of 12 coarse-grained configurations, with gains up to 4.5 percentage points while reducing feature dimensionality by 48-87%. The same projection consistently hurts on fine-grained CUB-200, where full features win across all six backbones. This establishes a practical boundary condition: LDA is useful when class-level structure is coarse enough to be captured by mean-separating directions, but it can discard subtle cues needed for fine-grained recognition. We also compare LDA with PCA, PCA+LDA, regularized LDA, Local Fisher Discriminant Analysis, Neighbourhood Components Analysis, and three lightweight LDA extensions. The results show that plain LDA offers the best accuracy-cost tradeoff for most coarse-grained settings, while more complex supervised reduction methods rarely justify their additional cost. Overall, the study provides concrete guidance for when post-hoc supervised projection should, and should not, be inserted into frozen-feature image classification pipelines.

Dense retrieval systems increasingly face an asymmetry between complex instruction-like queries and relatively simple, static document collections. While stronger embedders can better understand such queries, re-embedding large corpora or fine-tuning large models is often impractical. We propose Efficient Retrieval Adapter (ERA), a query-side adapter learning framework for re-index-free retrieval adaptation. ERA first aligns the embedding spaces of a strong query embedder and a lightweight document embedder using unlabeled corpus documents, and then adapts the aligned query representation with a small number of labeled query-document pairs. Across 126 MAIR retrieval tasks from six domains, ERA improves average nDCG@10 by up to 8.2 points in symmetric settings and by more than 12 points in asymmetric settings, while using substantially fewer labels than supervised adapter training. These results show that retrieval systems can benefit from stronger query understanding without updating backbone embedders or rebuilding document indexes.

The remarkable success of Convolutional Neural Networks (CNNs) and Vision Transformers (ViTs) in 2D vision has spurred significant research in extending these architectures to the complex domain of 3D analysis. Yet, a core challenge arises from a fundamental dichotomy between the regular, dense grids of 2D images and the irregular, sparse nature of 3D data such as point clouds and meshes. This survey provides a comprehensive review and a unified taxonomy of adaptation strategies that bridge this gap, classifying them into three families: (1) Data-centric methods that project 3D data into 2D formats to leverage off-the-shelf 2D models, (2) Architecture-centric methods that design intrinsic 3D networks, and (3) Hybrid methods, which synergistically combine the two modeling paradigms to benefit from both rich visual priors of large 2D datasets and explicit geometric reasoning of 3D models. Through this framework, we qualitatively analyze the fundamental trade-offs between these families concerning computational complexity, reliance on large-scale pre-training, and the preservation of geometric inductive biases. We discuss key open challenges and outline promising future research directions, including the development of 3D foundation models, advancements in self-supervised learning (SSL) for geometric data, and the deeper integration of multi-modal signals.

We introduce chaos-controlled Reservoir Computing (cc-RC) for living neural cultures: dynamically rich substrates of unique potential for adaptive computation. To account for intrinsic biological variability, cc-RC combines: (i) pre-training identification of each culture's dynamical signature and phase-portrait attractor; (ii) low-power optical chaos control to stabilize spontaneous and stimulus-evoked activity; (iii) readout training within this controlled regime. Across hundreds of neural samples, cc-RC enables robust learning and pattern classification, improving both accuracy and model longevity by approximately 300% over standard RC. We further propose Knowledge Transplant (KT), for which the reservoir map learned by an expert culture is transplanted to an attractor-equivalent student culture, reducing training time to minutes while improving performance. By enabling cross-substrate, reusable learned models, KT paves the way for knowledge accumulation and sharing across neural populations, transcending biological lifespan limits.

Dynamical systems describe how a physical system evolves over time. Physical processes can evolve faster or slower in different environmental conditions. We use time-warping as rescaling the time in a model of a physical system. This thesis proposes a new method of transfer learning for Recurrent Neural Networks (RNNs) based on time-warping. We prove that for a class of linear, first-order differential equations known as time lag models, an LSTM can approximate these systems with any desired accuracy, and the model can be time-warped while maintaining the approximation accuracy. The Time-Warping method of transfer learning is then evaluated in an applied problem on predicting fuel moisture content (FMC), an important concept in wildfire modeling. An RNN with LSTM recurrent layers is pretrained on fuels with a characteristic time scale of 10 hours, where there are large quantities of data available for training. The RNN is then modified with transfer learning to generate predictions for fuels with characteristic time scales of 1 hour, 100 hours, and 1000 hours. The Time-Warping method is evaluated against several known methods of transfer learning. The Time-Warping method produces predictions with an accuracy level comparable to the established methods, despite modifying only a small fraction of the parameters that the other methods modify.

Transfer learning (TL) and deep ensemble learning (DE) have recently been shown to outperform simple machine learning in classifying psychiatric disorders. However, there is still a lack of understanding as to why that is. This paper aims to understand how and why DE and TL reduce the variability of single-subject classification models in bipolar disorder (BD) and schizophrenia (SCZ). To this end, we investigated the training stability of TL and DE models. For the two classification tasks under consideration, we compared the results of multiple trainings with the same backbone but with different initializations. In this way, we take into account the epistemic uncertainty associated with the uncertainty in the estimation of the model parameters. It has been shown that the performance of classifiers can be significantly improved by using TL with DE. Based on these results, we investigate i) how many models are needed to benefit from the performance improvement of DE when classifying BD and SCZ from healthy controls, and ii) how TL induces better generalization, with and without DE. In the first case, we show that DE reaches a plateau when 10 models are included in the ensemble. In the second case, we find that using a pre-trained model constrains TL models with the same pre-training to stay in the same basin of the loss function. This is not the case for DL models with randomly initialized weights.

The ratio of outlier parameters in language pre-training models and vision pre-training models differs significantly, making cross-modality (language and vision) inherently more challenging than cross-domain adaptation. As a result, many prior studies have focused on cross-domain transfer rather than attempting to bridge language and vision modalities, assuming that language pre-trained models are unsuitable for downstream visual tasks due to disparate parameter spaces. Contrary to this assumption, we show that adding a bridge training stage as a modality adaptation learner can effectively align Large Language Model (LLM) parameters with vision tasks. Specifically, we propose a simple yet powerful solution random label bridge training that requires no manual labeling and helps LLM parameters adapt to vision foundation tasks. Moreover, our findings reveal that partial bridge training is often advantageous, as certain layers in LLMs exhibit strong foundational properties that remain beneficial even without fine-tuning for visual tasks. This surprising discovery opens up new avenues for leveraging language pre-trained parameters directly within vision models and highlights the potential of partial bridge training as a practical pathway to cross-modality adaptation.

This paper introduces two transfer learning methodologies for estimating nonparametric Bayesian networks under scarce data. We propose two algorithms, a constraint-based structure learning method, called PC-stable-transfer learning (PCS-TL), and a score-based method, called hill climbing transfer learning (HC-TL). We also define particular metrics to tackle the negative transfer problem in each of them, a situation in which transfer learning has a negative impact on the model's performance. Then, for the parameters, we propose a log-linear pooling approach. For the evaluation, we learn kernel density estimation Bayesian networks, a type of nonparametric Bayesian network, and compare their transfer learning performance with the models alone. To do so, we sample data from small, medium and large-sized synthetic networks and datasets from the UCI Machine Learning repository. Then, we add noise and modifications to these datasets to test their ability to avoid negative transfer. To conclude, we perform a Friedman test with a Bergmann-Hommel post-hoc analysis to show statistical proof of the enhanced experimental behavior of our methods. Thus, PCS-TL and HC-TL demonstrate to be reliable algorithms for improving the learning performance of a nonparametric Bayesian network with scarce data, which in real industrial environments implies a reduction in the required time to deploy the network.

Robust person tracking is a critical capability for autonomous mobile robots operating in diverse and unpredictable environments. While RGB-D tracking has shown high precision, its performance severely degrades under challenging illumination conditions, such as total darkness or intense backlighting. To achieve all-weather robustness, this paper proposes a novel Thermal-Infrared and Depth (TIR-D) tracking architecture that leverages the standard sensor suite of SLAM-capable robots, namely LiDAR and TIR cameras. A major challenge in TIR-D tracking is the scarcity of annotated multi-modal datasets. To address this, we introduce a sequential knowledge transfer strategy that evolves structural priors from a large-scale thermal-trained model into the TIR-D domain. By employing a differential learning rate strategy -- referred to as ``Fine-grained Differential Learning Rate Strategy'' -- we effectively preserve pre-trained feature extraction capabilities while enabling rapid adaptation to geometric depth cues. Experimental results demonstrate that our proposed TIR-D tracker achieves superior performance, with an Average Overlap (AO) of 0.700 and a Success Rate (SR) of 58.7%, significantly outperforming conventional RGB-transfer and single-modality baselines. Our approach provides a practical and resource-efficient solution for robust human-following in all-weather robotics applications.

Training relational foundation models requires learning representations that transfer across tasks, yet available supervision is typically limited to a small number of prediction targets per database. This task scarcity causes learned representations to encode task-specific shortcuts that degrade transfer even within the same schema, a problem we call label leakage. We study this using K-Space, a modular architecture combining frozen pretrained tabular encoders with a lightweight message-passing core. To suppress leakage, we introduce a gradient projection method that removes label-predictive directions from representation updates. On RelBench, this improves within-dataset transfer by +0.145 AUROC on average, often recovering near single-task performance. Our results suggest that limited task diversity, not just limited data, constrains relational foundation models.

In transfer learning, the learner leverages auxiliary data to improve generalization on a main task. However, the precise theoretical understanding of when and how auxiliary data help remains incomplete. We provide new insights on this issue in two canonical linear settings: ordinary least squares regression and under-parameterized linear neural networks. For linear regression, we derive exact closed-form expressions for the expected generalization error with bias-variance decomposition, yielding necessary and sufficient conditions for auxiliary tasks to improve generalization on the main task. We also derive globally optimal task weights as outputs of solvable optimization programs, with consistency guarantees for empirical estimates. For linear neural networks with shared representations of width $q \leq K$, where $K$ is the number of auxiliary tasks, we derive a non-asymptotic expectation bound on the generalization error, yielding the first non-vacuous sufficient condition for beneficial auxiliary learning in this setting, as well as principled directions for task weight curation. We achieve this by proving a new column-wise low-rank perturbation bound for random matrices, which improves upon existing bounds by preserving fine-grained column structures. Our results are verified on synthetic data simulated with controlled parameters.

This paper presents new resources and baselines for Dependency Parsing in Pomak, an endangered Eastern South Slavic language with substantial dialectal variation and no widely adopted standard. We focus on the variety spoken in Turkey (Uzunköprü) and ask how well a dependency parser trained on the existing Pomak Universal Dependencies treebank, which was built primarily from the variety that is spoken in Greece, transfers across dialects. We run two experimental phases. First, we train a parser on the Greek-variety UD data and evaluate zero-shot transfer to Turkish-variety Pomak, quantifying the impact of phonological and morphosyntactic differences. Second, we introduce a new manually annotated Turkish-variety Pomak corpus of 650 sentences and show that, despite its small size, targeted fine-tuning substantially improves accuracy; performance is further boosted by cross-variety transfer learning that combines the two dialects.

Deep learning models for drug-like molecules and proteins overwhelmingly reuse transformer architectures designed for natural language, yet whether molecular sequences benefit from different designs has not been systematically tested. We deploy autonomous architecture search via an agent across three sequence types (SMILES, protein, and English text as control), running 3,106 experiments on a single GPU. For SMILES, architecture search is counterproductive: tuning learning rates and schedules alone outperforms the full search (p = 0.001). For natural language, architecture changes drive 81% of improvement (p = 0.009). Proteins fall between the two. Surprisingly, although the agent discovers distinct architectures per domain (p = 0.004), every innovation transfers across all three domains with <1% degradation, indicating that the differences reflect search-path dependence rather than fundamental biological requirements. We release a decision framework and open-source toolkit for molecular modeling teams to choose between autonomous architecture search and simple hyperparameter tuning.

Recent studies have made notable progress in video representation learning by transferring image-pretrained models to video tasks, typically with complex temporal modules and video fine-tuning. However, fine-tuning heavy modules may compromise inter-video semantic separability, i.e., the essential ability to distinguish objects across videos. While reducing the tunable parameters hinders their intra-video temporal consistency, which is required for stable representations of the same object within a video. This dilemma indicates a potential trade-off between the intra-video temporal consistency and inter-video semantic separability during image-to-video transfer. To this end, we propose the Consistency-Separability Trade-off Transfer Learning (Co-Settle) framework, which applies a lightweight projection layer on top of the frozen image-pretrained encoder to adjust representation space with a temporal cycle consistency objective and a semantic separability constraint. We further provide a theoretical support showing that the optimized projection yields a better trade-off between the two properties under appropriate conditions. Experiments on eight image-pretrained models demonstrate consistent improvements across multiple levels of video tasks with only five epochs of self-supervised training. The code is available at https://github.com/yafeng19/Co-Settle.

Transfer learning and knowledge distillation has recently gained a lot of attention in the deep learning community. One transfer approach, the student-teacher learning, has been shown to successfully create small'' student neural networks that mimic the performance of a much bigger and more complex teacher'' networks. In this paper, we investigate an extension to this approach and transfer from a non-neural-based machine learning pipeline as teacher to a neural network (NN) student, which would allow for joint optimization of the various pipeline components and a single unified inference engine for multiple ML tasks. In particular, we explore replacing the random forest classifier by transfer learning to a student NN. We experimented with various NN topologies on 100 OpenML tasks in which random forest has been one of the best solutions. Our results show that for the majority of the tasks, the student NN can indeed mimic the teacher if one can select the right NN hyper-parameters. We also investigated the use of random forest for selecting the right NN hyper-parameters.

Transfer learning is a crucial concept within deep learning that allows artificial neural networks to benefit from a large pre-training data basis when confronted with a task of limited data. Despite its ubiquitous use and clear benefits, there are still many open questions regarding the inner workings of transfer learning and, in particular, regarding the understanding of when and how well it works. To that extent, we perform a rigorous study focusing on audio-to-audio transfer learning, in which we pre-train various model states on (ontology-based) subsets of AudioSet and fine-tune them on three computer audition tasks, namely acoustic scene recognition, bird activity recognition, and speech command recognition. We report that increasing the number of samples and classes in the pre-training data both have a positive impact on transfer learning. This is, however, generally surpassed by similarity between pre-training and the downstream task, which can lead the model to learn comparable features.

Accurate segmentation of the left atrial (LA) wall in 3D late gadolinium-enhanced MRI (LGE-MRI) is essential for wall thickness mapping and fibrosis quantification, yet it remains challenging due to the wall's thin geometry, complex anatomy, and low contrast. We propose C2W-Tune, a two-stage cavity-to-wall transfer framework that leverages a high-accuracy LA cavity model as an anatomical prior to improve thin-wall delineation. Using a 3D U-Net with a ResNeXt encoder and instance normalization, Stage 1 pre-trains the network to segment the LA cavity, learning robust atrial representations. Stage 2 transfers these weights and adapts the network to LA wall segmentation using a progressive layer-unfreezing schedule to preserve cavity features while enabling wall-specific refinement. On the 2018 LA Segmentation Challenge dataset, C2W-Tune outperformed an architecture-matched baseline trained from scratch. The wall Dice score increased from 0.623 to 0.814, surface Dice at 1 mm increased from 0.553 to 0.731, 95th-percentile Hausdorff distance (HD95) decreased from 2.95 mm to 2.55 mm, and average symmetric surface distance (ASSD) decreased from 0.71 mm to 0.63 mm. Under reduced supervision using 70 training volumes sampled from the same training set, C2W-Tune achieved a Dice of 0.78, remaining competitive with recent multi-class bi-atrial benchmarks, typically 0.6-0.7. These results show that anatomically grounded task transfer with controlled fine-tuning improves accuracy for thin LA wall segmentation in 3D LGE-MRI.

Machine-learned interatomic potentials (MLIPs), particularly graph neural network (GNN)-based models, offer a promising route to achieving near-density functional theory (DFT) accuracy at significantly reduced computational cost. However, their practical deployment is often limited by the large volumes of expensive quantum mechanical training data required. In this work, we introduce a transfer learning framework, Transfer-PaiNN (T-PaiNN), that substantially improves the data efficiency of GNN-MLIPs by leveraging inexpensive classical force field data. The approach consists of pretraining a PaiNN MLIP architecture on large-scale datasets generated from classical molecular simulations, followed by fine-tuning (dubbed autotuning) using a comparatively small DFT dataset. We demonstrate the effectiveness of autotuning T-PaiNN on both gas-phase molecular systems (QM9 dataset) and condensed-phase liquid water. Across all cases, T-PaiNN significantly outperforms models trained solely on DFT data, achieving order-of-magnitude reductions in mean absolute error while accelerating training convergence. For example, using the QM9 data set, error reductions of up to 25 times are observed in low-data regimes, while liquid water simulations show improved predictions of energies, forces, and experimentally relevant properties such as density and diffusion. These gains arise from the model's ability to learn general features of the potential energy surface from extensive classical sampling, which are subsequently refined to quantum accuracy. Overall, this work establishes transfer learning from classical force fields as a practical and computationally efficient strategy for developing high-accuracy, data-efficient GNN interatomic potentials, enabling broader application of MLIPs to complex chemical systems.

Accurate forecasting of state-of-health (SOH) is essential for ensuring safe and reliable operation of lithium-ion cells. However, existing models calibrated on laboratory tests at specific conditions often fail to generalize to new cells that differ due to small manufacturing variations or operate under different conditions. To address this challenge, an uncertainty-aware transfer learning framework is proposed, combining a Long Short-Term Memory (LSTM) model with domain adaptation via Maximum Mean Discrepancy (MMD) and uncertainty quantification through Conformal Prediction (CP). The LSTM model is trained on a virtual battery dataset designed to capture real-world variability in electrode manufacturing and operating conditions. MMD aligns latent feature distributions between simulated and target domains to mitigate domain shift, while CP provides calibrated, distribution-free prediction intervals. This framework improves both the generalization and trustworthiness of SOH forecasts across heterogeneous cells.

Frailty is a condition in aging medicine characterized by diminished physiological reserve and increased vulnerability to stressors. However, frailty assessment remains subjective, heterogeneous, and difficult to scale in clinical practice. Gait is a sensitive marker of biological aging, capturing multisystem decline before overt disability. Yet the application of modern computer vision to gait-based frailty assessment has been limited by small, imbalanced datasets and a lack of clinically representative benchmarks. In this work, we introduce a publicly available silhouette-based frailty gait dataset collected in a clinically realistic setting, spanning the full frailty spectrum and including older adults who use walking aids. Using this dataset, we evaluate how pretrained gait recognition models can be adapted for frailty classification under limited data conditions. We study both convolutional and hybrid attention-based architectures and show that predictive performance depends primarily on how pretrained representations are transferred rather than architectural complexity alone. Across models, selectively freezing low-level gait representations while allowing higher-level features to adapt yields more stable and generalizable performance than either full fine-tuning or rigid freezing. Conservative handling of class imbalance further improves training stability, and combining complementary learning objectives enhances discrimination between clinically adjacent frailty states. Interpretability analyses reveal consistent model attention to lower-limb and pelvic regions, aligning with established biomechanical correlates of frailty. Together, these findings establish gait-based representation learning as a scalable, non-invasive, and interpretable framework for frailty assessment and support the integration of modern biometric modeling approaches into aging research and clinical practice.

Medical imaging models frequently fail when deployed across hospitals, scanners, populations, or imaging protocols due to domain shift, limiting their clinical reliability. While transfer learning and domain adaptation address such shifts statistically, they often rely on spurious correlations that break under changing conditions. On the other hand, causal inference provides a principled way to identify invariant mechanisms that remain stable across environments. This survey introduces and systematises Causal Transfer Learning (CTL) for medical image analysis. This paradigm integrates causal reasoning with cross-domain representation learning to enable robust and generalisable clinical AI. We frame domain shift as a causal problem and analyse how structural causal models, invariant risk minimisation, and counterfactual reasoning can be embedded within transfer learning pipelines. We studied spanning classification, segmentation, reconstruction, anomaly detection, and multimodal imaging, and organised them by task, shift type, and causal assumption. A unified taxonomy is proposed that connects causal frameworks and transfer mechanisms. We further summarise datasets, benchmarks, and empirical gains, highlighting when and why causal transfer outperforms correlation-based domain adaptation. Finally, we discuss how CTL supports fairness, robustness, and trustworthy deployment in multi-institutional and federated settings, and outline open challenges and research directions for clinically reliable medical imaging AI.

Vision-language models (VLMs) have shown remarkable general capabilities, yet embodied agents built on them fail at complex tasks, often skipping critical steps, proposing invalid actions, and repeating mistakes. These failures arise from a fundamental gap between the static training data of VLMs and the physical interaction for embodied tasks. VLMs can learn rich semantic knowledge from static data but lack the ability to interact with the world. To address this issue, we introduce ELITE, an embodied agent framework with {E}xperiential {L}earning and {I}ntent-aware {T}ransfer that enables agents to continuously learn from their own environment interaction experiences, and transfer acquired knowledge to procedurally similar tasks. ELITE operates through two synergistic mechanisms, i.e., self-reflective knowledge construction and intent-aware retrieval. Specifically, self-reflective knowledge construction extracts reusable strategies from execution trajectories and maintains an evolving strategy pool through structured refinement operations. Then, intent-aware retrieval identifies relevant strategies from the pool and applies them to current tasks. Experiments on the EB-ALFRED and EB-Habitat benchmarks show that ELITE achieves 9% and 5% performance improvement over base VLMs in the online setting without any supervision. In the supervised setting, ELITE generalizes effectively to unseen task categories, achieving better performance compared to state-of-the-art training-based methods. These results demonstrate the effectiveness of ELITE for bridging the gap between semantic understanding and reliable action execution.

Retinal diseases remain among the leading preventable causes of visual impairment worldwide. Automated screening based on fundus image analysis has the potential to expand access to early detection, particularly in underserved populations. This paper presents a reproducible deep learning pipeline for binary retinal disease risk classification from publicly available fundus photographs. We implement and compare a baseline convolutional neural network with a transfer learning approach using a pretrained VGG16 backbone and evaluate generalization on held-out data. To address class imbalance, we apply class weighting and report standard classification metrics including accuracy, precision, recall, F1-score, confusion matrices, and ROC-AUC. The VGG16 transfer learning model achieves 90.8% test accuracy with a weighted F1-score of 0.90, substantially outperforming the baseline CNN (83.1% accuracy). Results indicate that transfer learning improves discrimination compared to a baseline CNN, while also revealing remaining challenges in sensitivity to minority disease cases. We discuss practical limitations related to dataset characteristics, class imbalance, and threshold selection, and provide guidance for reproducibility and future improvements for clinically reliable screening

We introduce the Dual-View Pheromone Pathway Network (DPPN), an architecture that routes sparse attention through a persistent pheromone field over latent slot transitions, and use it to discover two independent requirements for persistent structural memory in neural networks. Through five progressively refined experiments using up to 10 seeds per condition across 5 model variants and 4 transfer targets, we identify a core principle: persistent memory requires a stable coordinate system, and any coordinate system learned jointly with the model is inherently unstable. We characterize three obstacles -- pheromone saturation, surface-structure entanglement, and coordinate incompatibility -- and show that neither contrastive updates, multi-source distillation, Hungarian alignment, nor semantic decomposition resolves the instability when embeddings are learned from scratch. Fixed random Fourier features provide extrinsic coordinates that are stable, structure-blind, and informative, but coordinate stability alone is insufficient: routing-bias pheromone does not transfer (10 seeds, p>0.05). DPPN outperforms transformer and random sparse baselines for within-task learning (AULC 0.700 vs 0.680 vs 0.670). Replacing routing bias with learning-rate modulation eliminates negative transfer: warm pheromone as a learning-rate prior achieves +0.003 on same-family tasks (17 seeds, p<0.05) while never reducing performance. A structure completion function over extrinsic coordinates produces +0.006 same-family bonus beyond regularization, showing the catch-22 between stability and informativeness is partially permeable to learned functions. The contribution is two independent requirements for persistent structural memory: (a) coordinate stability and (b) graceful transfer mechanism.