Vision Foundation Models

High-resolution (HR) land-cover mapping is often constrained by the high cost of dense HR annotations. We revisit this problem from the perspective of map super-resolution, which enhances coarse low-resolution (LR) land-cover products into HR maps at the resolution of the input imagery. Existing weakly supervised methods can leverage LR labels, but they typically use them to retrain dense predictors with substantial computational cost. We propose MapSR, a prompt-driven framework that decouples supervision from model training. MapSR uses LR labels once to extract class prompts from frozen vision foundation model features through a lightweight linear probe, after which HR mapping proceeds via training-free metric inference and graph-based prediction refinement. Specifically, class prompts are estimated by aggregating high-confidence HR features identified by the linear probe, and HR predictions are obtained by cosine-similarity matching followed by graph-based propagation for spatial refinement. Experiments on the Chesapeake Bay dataset show that MapSR achieves 59.64% mIoU without any HR labels, remaining competitive with the strongest weakly supervised baseline and surpassing a fully supervised baseline. Notably, MapSR reduces trainable parameters by four orders of magnitude and shortens training time from hours to minutes, enabling scalable HR mapping under limited annotation and compute budgets. The code is available at https://github.com/rikirikirikiriki/MapSR.

Eye tracking (ET) plays a critical role in augmented and virtual reality applications. However, rapidly deploying high-accuracy, on-device gaze estimation for new products remains challenging because hardware configurations (e.g., camera placement, camera pose, and illumination) often change across device generations. Visual foundation models (VFMs) excel on natural-image benchmarks and offer a promising path to rapid training and deployment; yet, we find that off-the-shelf VFMs still struggle to reach high accuracy on specialized near-eye infrared images. To close this gap, we introduce DistillGaze, a framework that distills a VFM using labeled synthetic data and unlabeled real data for rapid, high-accuracy on-device gaze estimation. DistillGaze proceeds in two stages. First, we adapt a VFM into a domain-specialized teacher using synthetic gaze labels and unlabeled real images. Synthetic data provide scalable, high-quality gaze supervision, while unlabeled real data bridges the synthetic-to-real domain gap. Second, we train an on-device student from both teacher guidance and self-training. Evaluated on a large-scale crowd-sourced dataset spanning more than 2,000 participants, DistillGaze reduces median gaze error by 58.6% relative to synthetic-only baselines while maintaining a lightweight 256K-parameter model suitable for real-time on-device deployment. More broadly, DistillGaze offers an efficient path to training and deploying ET models that adapt to hardware changes, and a recipe for combining synthetic supervision with unlabeled real data in on-device regression tasks.

Feed-forward foundation models for multi-view 3-dimensional (3D) reconstruction have been trained on large-scale datasets of perspective images; when tested on wide field-of-view images, e.g., from a fisheye camera, their performance degrades. This degradation arises from changes in spatial arrangements of pixels induced by the non-linear projection model that maps 3D points onto the 2D image plane. While one may surmise that training on fisheye images would resolve this problem, there are far fewer fisheye images with ground truth than perspective images, which limits generalization. To enable inference on imagery exhibiting high radial distortion, we propose \textit{Fisheye3R}, a novel adaptation framework that extends these multi-view 3D reconstruction foundation models to natively accommodate fisheye inputs without performance regression on perspective images. To address the scarcity of fisheye images and ground truth, we introduce flexible learning schemes that support self-supervised adaptation using only unlabeled perspective images and supervised adaptation without any fisheye training data. Extensive experiments across three foundation models, including VGGT, $π^3$, and MapAnything, demonstrate that our approach consistently improves camera pose, depth, point map, and field-of-view estimation on fisheye images. Code is available at https://github.com/android-xr/fisheye3r.

Fine-tuning foundation models for Earth Observation is computationally expensive, with high training time and memory demands for both training and deployment. Parameter-efficient methods reduce training cost but retain full inference complexity, while post-hoc compression optimizes inference only after costly full fine-tuning. We introduce SIMPLER, a pre-fine-tuning architecture selection method that reduces inference and deployment costs by identifying an effective model depth before adaptation. SIMPLER exploits stabilization of representations in deeper layers of pre-trained vision transformers: it computes layer-wise representation similarity on unlabeled task data and applies an automated scoring function to select redundant layers, with no gradients, magnitude heuristics, or hyperparameter tuning required. On Prithvi-EO-2, SIMPLER prunes up to 79% of parameters while retaining 94% of baseline performance, yielding a 2.1x training speedup and 2.6x inference speedup. The method generalizes to TerraMind (a multimodal EO foundation model) and ImageNet-pretrained ViT-MAE, demonstrating applicability across tasks, architectures, and spectral modalities. Code is available at https://gitlab.citius.gal/hpc4rs/simpler.

Deep learning underlies most modern approaches and tools in computer vision, including biomedical imaging. However, for interactive semantic segmentation (often called pixel classification in this context) and interactive object-level classification (object classification), feature-based shallow learning remains widely used. This is due to the diversity of data in this domain, the lack of large pretraining datasets, and the need for computational and label efficiency. In contrast, state-of-the-art tools for many other vision tasks in microscopy - most notably cellular instance segmentation - already rely on deep learning and have recently benefited substantially from vision foundation models (VFMs), particularly SAM. Here, we investigate whether VFMs can also improve pixel and object classification compared to current approaches. To this end, we evaluate several VFMs, including general-purpose models (SAM, SAM2, SAM3, DINOv3) and domain-specific ones ($μ$SAM, PathoSAM, KRONOS), in combination with shallow learning and attentive probing on five diverse and challenging datasets. Our results demonstrate consistent improvements over hand-crafted features and provide a clear pathway toward practical improvements. Furthermore, our study establishes a benchmark for VFMs in microscopy and informs future developments in this area.

Foundation models are used to extract transferable representations from large amounts of unlabeled data, typically via self-supervised learning (SSL). However, many of these models rely on architectures that offer limited interpretability, a critical issue in high-stakes domains such as medical imaging. We propose \model, a foundation model that is interpretable-by-design via a BagNet backbone whose small receptive fields generate class evidence maps that are faithful to the model's decision-making process. Additionally, \model{} incorporates a $2D$ projection layer during pretraining that enables direct visualization of the representation space, providing a dataset-level view of the learned structure including meaningful clinical clusters as well as potential spurious correlations. We trained \model{} on over 800,000 color fundus photographs from various sources to learn generalizable representations for different downstream tasks. Our model achieves performance comparable to RETFound, which has $16\times$ more parameters, while providing interpretable predictions on out-of-distribution data. These results suggest that large-scale SSL pretraining paired with inherent interpretability can lead to robust representations for retinal imaging. Code and pretrained models are available at \href{https://anonymous.4open.science/r/dual-ifm-3D5A/README.md}{www.anonymous.4open.science/dual-IFM}.

Material classification has emerged as a critical task in computer vision and graphics, supporting the assignment of accurate material properties to a wide range of digital and real-world applications. While traditionally framed as an image classification task, this domain faces significant challenges due to the scarcity of annotated data, limiting the accuracy and generalizability of trained models. Recent advances in vision-language foundation models (VLMs) offer promising avenues to address these issues, yet existing solutions leveraging these models still exhibit unsatisfying results in material recognition tasks. In this work, we propose a novel framework that effectively harnesses foundation models to overcome data limitations and enhance classification accuracy. Our method integrates two key innovations: (a) a robust image generation and auto-labeling pipeline that creates a diverse and high-quality training dataset with material-centric images, and automatically assigns labels by fusing object semantics and material attributes in text prompts; (b) a prior incorporation strategy to distill information from VLMs, combined with a joint fine-tuning method that optimizes a pre-trained vision foundation model alongside VLM-derived priors, preserving broad generalizability while adapting to material-specific features. Extensive experiments demonstrate significant improvements on multiple datasets. We show that our synthetic dataset effectively captures the characteristics of real world materials, and the integration of priors from vision-language models significantly enhances the final performance. The source code and dataset will be released.

Medical image segmentation (MIS) is a fundamental component of computer-assisted diagnosis and clinical decision support. Over the past decade, numerous architectures specifically tailored to medical imaging have emerged to address domain-specific challenges such as low contrast, small anatomical structures, and limited annotated data. In parallel, rapid progress in computer vision has produced highly capable general-purpose vision models (GP-VMs) originally designed for natural images. Despite their strong performance on standard vision benchmarks, their effectiveness for MIS remains insufficiently understood. In this controlled empirical study, we examine whether specialized medical segmentation architectures (SMAs) provide systematic advantages over modern GP-VMs for 2D MIS. We compare eleven SMAs and GP-VMs using a unified training and evaluation protocol across three heterogeneous datasets, each covering different 2D imaging modalities, class structures, and data characteristics. Beyond segmentation performance, we employ linear mixed-effects models (LMMs) for statistical assessment and qualitative Grad-CAM visualizations to investigate explainability (XAI)-related model behavior. Our results imply that, for the analyzed settings, GP-VMs achieve performance comparable to that of specialized MIS models. Moreover, XAI analyses indicate that GP-VMs are capable of identifying clinically relevant structures despite the absence of explicit domain-specific architectural priors. These findings suggest that GP-VMs can represent a viable alternative to domain-specific methods for 2D MIS, highlighting the importance of informed model selection. All code and resources are available at GitHub.

Radiology foundation models (RFMs) have largely inherited the scale-first recipe of natural-image vision--language pre-training. This recipe is difficult to deploy in 3D radiology, where training corpora are smaller, reports vary across institutions, and receiving hospitals often need local adaptation under privacy and compute constraints. We ask whether routine radiology reports can instead be converted into auditable diagnostic supervision that shapes the image encoder, text encoder, aligned space, and local-adaptation procedure. We develop GreenRFM, a supervision-centric pre-training framework organized around four empirical principles: More distilled, Ubiquitous, Semantic-enforcing, and Task-aligning (MUST) supervision. These principles convert noisy reports into structured diagnostic signals and use them to learn discriminative unimodal encoders plus an aligned image--text space for diagnosis-centered multimodal use. GreenRFM requires 24 GPU-hours on a single 24GB GPU (lightweight variant: 6GB VRAM, 4~hours) and reaches a zero-shot CT-RATE AUC of 84.8. Evaluations using more than 200,000 volumes from six institutions and two modalities show transfer to private clinical cohorts and to musculoskeletal MRI. On a local institutional cohort, computationally feasible retraining raises macro-AUC from 70.5 to 82.1. The aligned space also improves hepatocellular-carcinoma microvascular-invasion prediction and trans-arterial chemoembolization response analysis over established clinical scores. These results support supervision-centric pre-training as a practical route to resource-efficient, locally adaptable, diagnosis-centered radiology vision--language representations.

Glass surface segmentation from RGB images is a challenging task, with a number of applications in robotics and scene understanding. As glass lacks coherent visual characteristics, rich context and semantic information is crucial for accurate segmentation. Consequently, prior works on the task have explored utilization of foundation models and separate semantic backbones. This paper presents a novel dual-backbone architecture for glass segmentation, applying a frozen foundation model backbone in parallel with a learned backbone trained on task-specific segmentation data. The learned backbone enables the network to specialize to glass related visual clues, while preserving the general visual feature representations of the foundation model. The hierarchical multi-scale features acquired from the dual-backbone are compressed and decoded into segmentation masks. Benchmarking of the architecture was carried out on four commonly used glass segmentation datasets, achieving state-of-the-art results. Ablation studies highlight the performance gains of the dual-backbone design and demonstrate the generalizability of the architecture with different backbone choices. The model also has a competitive inference speed compared to the previous state-of-the-art method, and surpasses it when using a lighter backbone variant. The implementation source code and model weights are available at: https://github.com/ojalar/lgnet.

We present Xray-Visual, a unified vision model architecture for large-scale image and video understanding trained on industry-scale social media data. Our model leverages over 15 billion curated image-text pairs and 10 billion video-hashtag pairs from Facebook and Instagram, employing robust data curation pipelines that incorporate balancing and noise suppression strategies to maximize semantic diversity while minimizing label noise. We introduce a three-stage training pipeline that combines self-supervised MAE, semi-supervised hashtag classification, and CLIP-style contrastive learning to jointly optimize image and video modalities. Our architecture builds on a Vision Transformer backbone enhanced with efficient token reorganization (EViT) for improved computational efficiency. Extensive experiments demonstrate that Xray-Visual achieves state-of-the-art performance across diverse benchmarks, including ImageNet for image classification, Kinetics and HMDB51 for video understanding, and MSCOCO for cross-modal retrieval. The model exhibits strong robustness to domain shift and adversarial perturbations. We further demonstrate that integrating large language models as text encoders (LLM2CLIP) significantly enhances retrieval performance and generalization capabilities, particularly in real-world environments. Xray-Visual establishes new benchmarks for scalable, multimodal vision models, while maintaining superior accuracy and computational efficiency.

While foundation models have advanced surgical video analysis, current approaches rely predominantly on pixel-level reconstruction objectives that waste model capacity on low-level visual details, such as smoke, specular reflections, and fluid motion, rather than semantic structures essential for surgical understanding. We present SurgMotion, a video-native foundation model that shifts the learning paradigm from pixel-level reconstruction to latent motion prediction. Built on the Video Joint Embedding Predictive Architecture (V-JEPA), SurgMotion introduces three key technical innovations tailored to surgical videos: (1) motion-guided latent masked prediction to prioritize semantically meaningful regions, (2) spatiotemporal affinity self-distillation to enforce relational consistency, and (3) spatiotemporal feature diversity regularization (SFDR) to prevent representation collapse in texture-sparse surgical scenes. To enable large-scale pretraining, we curate SurgMotion-15M, the largest surgical video dataset to date, comprising 3,658 hours of video from 50 sources across 13 anatomical regions. Extensive experiments across 17 benchmarks demonstrate that SurgMotion significantly outperforms state-of-the-art methods on surgical workflow recognition, achieving 14.6 percent improvement in F1 score on EgoSurgery and 10.3 percent on PitVis; on action triplet recognition with 39.54 percent mAP-IVT on CholecT50; as well as on skill assessment, polyp segmentation, and depth estimation. These results establish SurgMotion as a new standard for universal, motion-oriented surgical video understanding.

Scaling has powered recent advances in vision foundation models, yet extending this paradigm to metric depth estimation remains challenging due to heterogeneous sensor noise, camera-dependent biases, and metric ambiguity in noisy cross-source 3D data. We introduce Metric Anything, a simple and scalable pretraining framework that learns metric depth from noisy, diverse 3D sources without manually engineered prompts, camera-specific modeling, or task-specific architectures. Central to our approach is the Sparse Metric Prompt, created by randomly masking depth maps, which serves as a universal interface that decouples spatial reasoning from sensor and camera biases. Using about 20M image-depth pairs spanning reconstructed, captured, and rendered 3D data across 10000 camera models, we demonstrate-for the first time-a clear scaling trend in the metric depth track. The pretrained model excels at prompt-driven tasks such as depth completion, super-resolution and Radar-camera fusion, while its distilled prompt-free student achieves state-of-the-art results on monocular depth estimation, camera intrinsics recovery, single/multi-view metric 3D reconstruction, and VLA planning. We also show that using pretrained ViT of Metric Anything as a visual encoder significantly boosts Multimodal Large Language Model capabilities in spatial intelligence. These results show that metric depth estimation can benefit from the same scaling laws that drive modern foundation models, establishing a new path toward scalable and efficient real-world metric perception. We open-source MetricAnything at http://metric-anything.github.io/metric-anything-io/ to support community research.

Visual Foundation Models (VFMs), such as DINO and CLIP, excel in semantic understanding of images but exhibit limited spatial reasoning capabilities, which limits their applicability to embodied systems. As a result, recent work incorporates some 3D tasks (such as depth estimation) into VFM training. However, VFM performance remains inconsistent across other spatial tasks, raising the question of whether these models truly have spatial awareness or overfit to specific 3D objectives. To address this question, we introduce the Spatial Relation Recognition Task (SpaRRTa) benchmark, which evaluates the ability of VFMs to identify relative positions of objects in the image. Unlike traditional 3D objectives that focus on precise metric prediction (e.g., surface normal estimation), SpaRRTa probes a fundamental capability underpinning more advanced forms of human-like spatial understanding. SpaRRTa generates an arbitrary number of photorealistic images with diverse scenes and fully controllable object arrangements, along with freely accessible spatial annotations. Evaluating a range of state-of-the-art VFMs, we reveal significant disparities between their spatial reasoning abilities. Through our analysis, we provide insights into the mechanisms that support or hinder spatial awareness in modern VFMs. We hope that SpaRRTa will serve as a useful tool for guiding the development of future spatially aware visual models.

Despite achieving strong results on standard benchmarks, current point tracking methods rely on feature backbones that are rarely designed with the temporal coherence needed for robust real-world performance. While recent works incorporate powerful visual foundation model (VFM) features into tracking pipelines, no prior work has systematically analyzed which VFM provides the most robust representations for point tracking. We present the first such analysis, evaluating diverse VFMs in a zero-shot setting on both standard and robustness benchmarks for point tracking. Our study reveals that video diffusion transformers (DiTs) consistently yield the most temporally coherent and discriminative features, even surpassing ResNet backbones explicitly supervised on tracking data. We hypothesize this advantage stem from large-scale video pretraining, full 3D spatio-temporal attention, and a diffusion training objective. Motivated by this finding, we propose DiTracker, which integrates video DiT features into existing tracking frameworks through query-key matching cost computation, cost-level fusion with a lightweight ResNet branch, and LoRA adaptation. Under the same tracking head, DiTracker is trained solely on synthetic data with far fewer iterations, yet outperforms CoTracker3 trained with additional real-world videos, with the largest gains under challenging and corrupted scenarios. It further generalizes across tracking heads and scales with backbone size, confirming that generative video pretraining provides real-world priors that reduce the dependence on large-scale real-data supervision.

Foundation models are vital tools in various Computer Vision applications. They take as input a single RGB image and output a deep feature representation that is useful for various applications. However, in case we have multiple views of the same 3D scene, they operate on each image independently and do not always produce consistent features for the same 3D point. We propose a way to convert a Foundation Model into a Multi-View Foundation Model. Such a model takes as input a set of images and outputs a feature map for each image such that the features of corresponding points are as consistent as possible. This approach bypasses the need to build a consistent 3D model of the features and allows direct manipulation in the image space. Specifically, we show how to augment Transformers-based foundation models (i.e., DINO, SAM, CLIP) with intermediate 3D-aware attention layers that help match features across different views. As leading examples, we show surface normal estimation and multi-view segmentation tasks. Quantitative experiments show that our method improves feature matching considerably compared to current foundation models.

Foundation Models (FMs) are increasingly integrated into remote sensing (RS) pipelines. These models include unimodal vision encoders and multimodal architectures. FMs are adapted to diverse perception tasks, such as image classification, change detection, and visual question answering. However, selecting the most suitable remote sensing foundation model (RSFM) for a specific task remains challenging due to scattered documentation, heterogeneous formats, and complex deployment constraints. To address this, we first introduce the RSFM Database (RS-FMD), the first structured and schema-guided resource covering over 160 RSFMs trained on various data modalities, spanning different spatial, spectral, and temporal resolutions, considering different learning paradigms. Built upon RS-FMD, we further present REMSA, a constraint-aware agent that enables automated RSFM selection from natural language queries. REMSA combines structured FM metadata retrieval with a task-driven decision workflow. In detail, it interprets user input, clarifies missing constraints, ranks models via in-context learning, and provides transparent justifications. Our system supports various RS tasks and data modalities, enabling personalized, reproducible, and efficient FM selection. To evaluate REMSA, we construct a benchmark of 100 expert-verified RS query scenarios. Each query is evaluated across 4 systems and 3 LLM backbones, with the top-3 selected models manually assessed by domain experts. This results in 3,000 expert-scored task--system--model configurations under our novel expert-centered evaluation protocol. REMSA outperforms multiple baselines, showing its practical utility in real decision-making applications. REMSA operates entirely on publicly available metadata of open source RSFMs, without accessing private or sensitive data.

While foundation models have emerged as general-purpose visual backbones, their representations are primarily optimized for semantics and lack explicit modeling of physical factors, such as reflectance, hindering their efficacy in tasks requiring explicit material reasoning. We introduce $Φ$eat$, a novel material-grounded visual backbone that encourages a representation sensitive to material identity, including reflectance and mesostructure. Instead of relying on generic data augmentations, we pretrain our model by contrasting observations of the same material under controlled variations in lighting and geometry. This encourages invariance to extrinsic factors while preserving sensitivity to intrinsic material properties. We show that the resulting representation provides strong priors for material-centric tasks, including feature-based material selection and classification. Our results demonstrate that physically inspired weak supervision is an effective strategy for learning representations tailored to material perception.

The data for remote sensing is constantly acquired, and new data comes from a growing number and diversity of satellites, while the vast majority of labeled data comes from older satellites. As remote-sensing foundation models for Earth observation scale up, the cost of (re-)training to support new satellites grows too, so cross-band generalization across sensors and satellites is increasingly important. We introduce GeoCrossBench, an extension of the popular GeoBench benchmark with a new evaluation protocol for cross-band generalization across sensors and satellites: it tests standard in-distribution performance with the same bands for train and test, generalization to inputs with no intersection between train and test; and generalization to test inputs containing a superset of the training bands. We develop $χ$ViT, a self-supervised extension of the band-agnostic ChannelViT, as a supporting baseline for cross-band generalization. We evaluate a representative set of remote-sensing-specific and general-purpose vision models, characterize current performance, and identify directions for improvement through 11,900 H100 GPU-hours of experiments. When averaging dataset-specific metric scores, DOFA leads the in-distribution setting (61.30), frozen Panopticon leads the no-overlap setting (22.75), and ImageNet-pretrained ViT-B leads both the superset setting (56.19) and the overall average across settings (45.27). While top rankings in each setting are close, we clearly see that all models suffer significant performance losses when evaluated on unseen bands. We will publicly release the code and datasets to support the development of more future-proof remote sensing models with stronger cross-band generalization.

Diabetic Macular Edema (DME) is a leading cause of vision loss among patients with Diabetic Retinopathy (DR). While deep learning has shown promising results for automatically detecting this condition from fundus images, its application remains challenging due the limited availability of annotated data. Foundation Models (FM) have emerged as an alternative solution. However, it is unclear if they can cope with DME detection in particular. In this paper, we systematically compare different FM and standard transfer learning approaches for this task. Specifically, we compare the two most popular FM for retinal images-RETFound and FLAIR-and an EfficientNetB0 backbone, across different training regimes and evaluation settings in IDRiD, MESSIDOR-2 and OCT-and-Eye-FundusImages (OEFI). Results show that despite their scale, FM do not consistently outperform fine-tuned CNNs in this task. In particular, EfficientNet-B0 consistently achieves competitive or superior performance across evaluation settings, with FLAIR being the most competitive foundation model, consistently outperforming RETFound. These findings suggest that FMs do not necessarily provide an advantage for fine-grained ophthalmic tasks such as DME detection, even after fine-tuning, highlighting lightweight CNNs as strong baselines in data-scarce environments.

Public datasets of Chest X-Rays (CXRs) have long been a popular benchmark for developing machine learning (ML) computer vision models in healthcare. However, the reported strong average-case performance of these models do not necessarily reflect their actual utility when used in heterogeneous clinical settings, potentially masking weaker performance in medically significant scenarios. In this work we use clinical context to provide a more holistic evaluation of models for CXR diagnosis. In particular, we use discharge summaries, recorded prior to each CXR, to derive a ``pre-CXR'' probability of each CXR label, as a proxy for existing contextual knowledge available to clinicians when interpreting CXRs. We use this measure to probe model performance along two dimensions: First, using a stratified analysis, we show that models tend to have lower performance (as measured by AUROC and other metrics) among individuals with higher pre-CXR probability. Second, by controlling for pre-CXR probability via matching and re-weighting, we demonstrate that performance degrades when the correlation is broken between prior context and the current CXR label, suggesting that model performance is highly sensitive to the underlying distribution of clinical context. Specifically, cases with high pre-test probabilities present a fundamentally more difficult visual classification task, highlighting a gap in clinical utility when models are applied to high-risk cohorts.

The emergence of audio-visual foundation models underscores the importance of reliably assessing their multi-modal understanding. The VGGSound dataset is commonly used as a benchmark for evaluation audio-visual classification. However, our analysis identifies several limitations of VGGSound, including incomplete labelling, partially overlapping classes, and misaligned modalities. These lead to distorted evaluations of auditory and visual capabilities. To address these limitations, we introduce VGGSounder, a comprehensively re-annotated, multi-label test set that extends VGGSound and is specifically designed to evaluate audio-visual foundation models. VGGSounder features detailed modality annotations, enabling precise analyses of modality-specific performance. Furthermore, we reveal model limitations by analysing performance degradation when adding another input modality with our new modality confusion metric.

Artificial intelligence (AI) shows remarkable potential in medical imaging diagnostics, yet most current models require retraining when applied across different clinical settings, limiting their scalability. We developed GlobeReady, a deployment-oriented platform powered by the RetiGlobe foun- dation model and local feature augmentation. RetiGlobe was pretrained in two stages: 1) self-supervised learning using DINOv2 on 38 million synthetic ophthalmic images, and 2) contrastive learning using CLIP on 475,845 real image-text pairs spanning diverse ethnicities, imaging devices, and geographic regions worldwide. We evaluate GlobeReady on 488,448 ophthalmic images, including color fundus photographs (CFPs) and optical coherence tomography scans, from multi-centres in China, Singapore, Vietnam and the UK. Prospective testing included usability assessment with 31 ophthalmologists. Exploratory analyses evaluated domain generalisability, Bayesian uncertainty quantification, out-of-distribution (OOD) detection, and feature-based case retrieval.

Previous studies on federated learning (FL) often encounter performance degradation due to data heterogeneity among different clients. In light of the recent advances in multimodal large language models (MLLMs), such as GPT-4v and LLaVA, which demonstrate their exceptional proficiency in multimodal tasks, such as image captioning and multimodal question answering. We introduce a novel federated learning framework, named Multimodal Large Language Model Assisted Federated Learning (MLLM-LLaVA-FL), which employs powerful MLLMs at the server end to address the heterogeneous and long-tailed challenges. Owing to the advanced cross-modality representation capabilities and the extensive open-vocabulary prior knowledge of MLLMs, our framework is adept at harnessing the extensive, yet previously underexploited, open-source data accessible from websites and powerful server-side computational resources. Hence, the MLLM-LLaVA-FL not only enhances the performance but also avoids increasing the risk of privacy leakage and the computational burden on local devices, distinguishing it from prior methodologies. Our framework has three key stages. Initially, we conduct global visual-text pretraining of the model. This pretraining is facilitated by utilizing the extensive open-source data available online, with the assistance of MLLMs. Subsequently, the pretrained model is distributed among various clients for local training. Finally, once the locally trained models are transmitted back to the server, a global alignment is carried out under the supervision of MLLMs to further enhance the performance. Experimental evaluations on established benchmarks, show that our framework delivers promising performance in the typical scenarios with data heterogeneity and long-tail distribution across different clients in FL.

Efficiently merging several models fine-tuned for different tasks, but stemming from the same pretrained base model, is of great practical interest. Despite extensive prior work, most evaluations of model merging in computer vision are restricted to image classification using CLIP, where different classification datasets define different tasks. In this work, our goal is to make model merging more practical and show its relevance on challenging scenarios beyond this specific setting. In most vision scenarios, different tasks rely on trainable and usually heterogeneous decoders. Differently from previous studies with frozen decoders, where merged models can be evaluated right away, the non-trivial cost of decoder training renders hyperparameter selection based on downstream performance impractical. To address this, we introduce the task alignment proxy, and show how it can be used to speed up hyperparameter selection by orders of magnitude while retaining performance. Equipped with the task alignment proxy, we extend the applicability of model merging to multi-task vision models beyond CLIP-based classification. Project page: https://europe.naverlabs.com/task-alignment

Current methods for multimodal medical image classification (M3IC) face two major challenges. First, the prevailing "fusion after unimodal image embedding" paradigm cannot fully exploit the complementary and correlated information in the multimodal data. Second, the scarcity of labeled multimodal medical images, coupled with their substantial domain shift from natural images, impedes the use of cutting-edge Vision Foundation Models (VFMs) for medical image embedding. To jointly address the challenges, we propose a novel Early Intervention (EI) framework. Treating one modality as target and the rest as reference, EI harnesses high-level semantic tokens from the reference as intervention tokens to steer the target modality's embedding process at an early stage. For parameter-efficient VFM adaptation, we introduce Mixture of varied-rank LoRAs (MoR), which employs a small set of LoRA experts with distinct ranks and a bypass-allowed router. Extensive experiments on three public datasets, covering retinal disease recognition, skin lesion recognition, and knee anomaly classification, verify the effectiveness of the proposed method against a number of competitive baselines.

In the era of information explosion, efficiently leveraging large-scale unlabeled data while minimizing the reliance on high-quality pixel-level annotations remains a critical challenge in the field of medical imaging. Semi-supervised learning (SSL) enhances the utilization of unlabeled data by facilitating knowledge transfer, significantly improving the performance of fully supervised models and emerging as a highly promising research direction in medical image analysis. Inspired by the ability of Vision Foundation Models (e.g., SAM-2) to provide rich prior knowledge, we propose SSS (Semi-Supervised SAM-2), a novel approach that leverages SAM-2's robust feature extraction capabilities to uncover latent knowledge in unlabeled medical images, thus effectively enhancing feature support for fully supervised medical image segmentation. Specifically, building upon the single-stream "weak-to-strong" consistency regularization framework, this paper introduces a Discriminative Feature Enhancement (DFE) mechanism to further explore the feature discrepancies introduced by various data augmentation strategies across multiple views. By leveraging feature similarity and dissimilarity across multi-scale augmentation techniques, the method reconstructs and models the features, thereby effectively optimizing the salient regions. Furthermore, a prompt generator is developed that integrates Physical Constraints with a Sliding Window (PCSW) mechanism to generate input prompts for unlabeled data, fulfilling SAM-2's requirement for additional prompts. Extensive experiments demonstrate the superiority of the proposed method for semi-supervised medical image segmentation on two multi-label datasets, i.e., ACDC and BHSD. Notably, SSS achieves an average Dice score of 53.15 on BHSD, surpassing the previous state-of-the-art method by +3.65 Dice. Code will be available at https://github.com/AIGeeksGroup/SSS.