Conditional Generative Modeling

Overview

Conditional generative modeling studies how to generate plausible data given information such as labels, text, images, measurements, or physical parameters. Common approaches include conditional GANs and VAEs, normalizing flows, diffusion and score-based models, flow matching, and autoregressive or masked models. These methods support tasks such as image reconstruction, time-series forecasting, molecular design, and scientific inverse problems, where many possible outputs may fit the same input. A central challenge is balancing fidelity to the condition and output diversity with fast sampling, reliable uncertainty, and generalization to unseen conditions.

Latest papers

393 papers53 papers in the last four weeks, up 39% on the four weeks before. 0.3% of all new papers.

Mar 3, 2026

COP-GEN: Latent Diffusion Transformer for Copernicus Earth Observation Data

Earth observation applications increasingly rely on data from multiple sensors, including optical, radar, elevation, and land-cover. Relationships between modalities are fundamental for data integration but are inherently non-injective: identical conditioning information can correspond to multiple physically plausible observations, and should be parametrised as conditional distributions. Deterministic models, by contrast, collapse toward conditional means and fail to represent the uncertainty and variability required for tasks such as data completion and cross-sensor translation. We introduce COP-GEN, a multimodal latent diffusion transformer that models the joint distribution of heterogeneous EO modalities at their native spatial resolutions. By parameterising cross-modal mappings as conditional distributions, COP-GEN enables flexible any-to-any conditional generation, including zero-shot modality translation without task-specific retraining. Experiments show that COP-GEN generates diverse yet physically consistent realisations while maintaining strong peak fidelity across optical, radar, and elevation modalities. Qualitative and quantitative analyses demonstrate that the model captures meaningful cross-modal structure and adapts its output uncertainty as conditioning information increases. We release a stochastic benchmark built from multi-temporal Sentinel-2 observations that enables distribution-level comparison of generative EO models. On this benchmark, COP-GEN covers 90% of the real observation manifold and 63% of its per-band reflectance range, while the strongest competing method collapses to 2.8% and 18%, respectively. These results highlight the importance of stochastic generative modeling for EO and motivate evaluation protocols beyond single-reference, pointwise metrics. Website: https://miquel-espinosa.github.io/cop-gen
Mar 3, 2026

Unifying Contrastive and Generative Objectives for Visual Understanding and Text-to-Image Generation

Unifying text-image contrastive learning and text-to-image (T2I) generation in a single end-to-end model is challenging because the two objectives demand opposing masking regimes: contrastive alignment needs near-complete visible tokens, while masked generative modeling needs heavy corruption. We introduce DREAM, a unified framework that resolves this conflict through Masking Warmup, a schedule that shifts the center of the masking distribution over training, so low and high masking ratios coexist at every step. This co-exposure lets a single jointly-trained encoder serve both objectives. The resulting stable optimization unlocks Semantically Aligned Decoding at inference: the text encoder, trained against visual embeddings at all masking ratios, can score partially generated images and select the best trajectory with as little as 12.5% of the image decoded, improving both FID and throughput. DREAM outperforms its single-objective baselines, CLIP and FLUID: on ImageNet linear-probing (+1.1%), 5-shot transfer (+4.1%), ADE20K segmentation (+1.9%), and NYU depth estimation (+6.25%) over CLIP, and on CC12M FID (+6.2%) over FLUID while maintaining CLIP Score. Together, these gains show that text-image contrastive and generative objectives, when properly unified, are synergistic rather than competing.
Mar 1, 2026

Data-Efficient Brushstroke Generation with Diffusion Models for Oil Painting

Many creative multimedia systems are built upon visual primitives such as strokes or textures, which are difficult to collect at scale and fundamentally different from natural image data. This data scarcity makes it challenging for modern generative models to learn expressive and controllable primitives, limiting their use in process-aware content creation. In this work, we study the problem of learning human-like brushstroke generation from a small set of hand-drawn samples (n=470) and propose StrokeDiff, a diffusion-based framework with Smooth Regularization (SmR). SmR injects stochastic visual priors during training, providing a simple mechanism to stabilize diffusion models under sparse supervision without altering the inference process. We further show how the learned primitives can be made controllable through a Bézier-based conditioning module and integrated into a complete stroke-based painting pipeline, including prediction, generation, ordering, and compositing. This demonstrates how data-efficient primitive modeling can support expressive and structured multimedia content creation. Experiments indicate that the proposed approach produces diverse and structurally coherent brushstrokes and enables paintings with richer texture and layering, validated by both automatic metrics and human evaluation.
Feb 24, 2026

BoxSplitGen: A Generative Model for 3D Part Bounding Boxes in Varying Granularity

Human creativity follows a perceptual process, moving from abstract ideas to finer details during creation. While 3D generative models have advanced dramatically, models specifically designed to assist human imagination in 3D creation -- particularly for detailing abstractions from coarse to fine -- have not been explored. We propose a framework that enables intuitive and interactive 3D shape generation by iteratively splitting bounding boxes to refine the set of bounding boxes. The main technical components of our framework are two generative models: the box-splitting generative model and the box-to-shape generative model. The first model, named BoxSplitGen, generates a collection of 3D part bounding boxes with varying granularity by iteratively splitting coarse bounding boxes. It utilizes part bounding boxes created through agglomerative merging and learns the reverse of the merging process -- the splitting sequences. The model consists of two main components: the first learns the categorical distribution of the box to be split, and the second learns the distribution of the two new boxes, given the set of boxes and the indication of which box to split. The second model, the box-to-shape generative model, is trained by leveraging the 3D shape priors learned by an existing 3D diffusion model while adapting the model to incorporate bounding box conditioning. In our experiments, we demonstrate that the box-splitting generative model outperforms token prediction models and the inpainting approach with an unconditional diffusion model. Also, we show that our box-to-shape model, based on a state-of-the-art 3D diffusion model, provides superior results compared to a previous model.
Feb 23, 2026

An LLM-Enabled Frequency-Aware Flow Diffusion Model for Natural-Language-Guided Power System Scenario Generation

Diverse and controllable scenario generation (e.g., wind, solar, load, etc.) is critical for robust power system planning and operation. As AI-based scenario generation methods are becoming the mainstream, existing methods (e.g., Conditional Generative Adversarial Nets) mainly rely on a fixed-length numerical conditioning vector to control the generation results, facing challenges in user conveniency and generation flexibility. In this paper, a natural-language-guided scenario generation framework, named LLM-enabled Frequency-aware Flow Diffusion (LFFD), is proposed to enable users to generate desired scenarios using plain human language. First, a pretrained LLM module is introduced to convert generation requests described by unstructured natural languages into ordered semantic space. Second, instead of using standard diffusion models, a flow diffusion model employing a rectified flow matching objective is introduced to achieve efficient and high-quality scenario generation, taking the LLM output as the model input. During the model training process, a frequency-aware multi-objective optimization algorithm is introduced to mitigate the frequency-bias issue. Meanwhile, a dual-agent framework is designed to create text-scenario training sample pairs as well as to standardize semantic evaluation. Experiments based on large-scale photovoltaic and load datasets demonstrate the effectiveness of the proposed method.
Feb 21, 2026

GenPlanner: From Noise to Plans -- Emergent Reasoning in Flow Matching and Diffusion Models

Path planning in complex environments is one of the key problems of artificial intelligence because it requires simultaneous understanding of the geometry of space and the global structure of the problem. In this paper, we explore the potential of using generative models as planning and reasoning mechanisms. We propose GenPlanner, an approach based on diffusion models and flow matching, along with two variants: DiffPlanner and FlowPlanner. We demonstrate the application of generative models to find and generate correct paths in mazes. A multi-channel condition describing the structure of the environment, including an obstacle map and information about the starting and destination points, is used to condition trajectory generation. Unlike standard methods, our models generate trajectories iteratively, starting with random noise and gradually transforming it into a correct solution. Experiments conducted show that the proposed approach significantly outperforms the baseline CNN model. In particular, FlowPlanner demonstrates high performance even with a limited number of generation steps.
Feb 20, 2026

Narrating For You: Prompt-guided Audio-visual Narrating Face Generation Employing Multi-entangled Latent Space

We present a novel approach for generating realistic speaking and talking faces by synthesizing a person's voice and facial movements from a static image, a voice profile, and a target text. The model encodes the prompt/driving text, the driving image, and the voice profile of an individual and then combines them to pass them to the multi-entangled latent space to foster key-value pairs and queries for the audio and video modality generation pipeline. The multi-entangled latent space is responsible for establishing the spatiotemporal person-specific features between the modalities. Further, entangled features are passed to the respective decoder of each modality for output audio and video generation.
Feb 13, 2026

Native Extrapolation Awareness in Flow-Based Conditional Generation

The ability of Flow Matching (FM) to model complex conditional distributions has established it as the state-of-the-art for prediction tasks (e.g., robotics, weather forecasting). However, deployment in safety-critical settings is hindered by a critical extrapolation hazard: driven by smoothness biases, flow models yield plausible outputs even for off-manifold conditions, resulting in silent failures indistinguishable from valid predictions. In this work, we introduce Diverging Flows, a novel approach that enables a single model to simultaneously perform conditional generation and native extrapolation detection by structurally enforcing inefficient transport for off-manifold inputs. We evaluate our method on synthetic manifolds, cross-domain style transfer, and weather temperature forecasting, demonstrating that it achieves effective detection of extrapolations without compromising predictive fidelity or inference latency. These results establish Diverging Flows as a robust solution for trustworthy flow models, paving the way for reliable deployment in domains such as medicine, robotics, and climate science.
Jan 28, 2026

ECGFlowCMR: Pretraining with ECG-Generated Cine CMR Helps Cardiac Disease Classification and Phenotype Prediction

Cardiac Magnetic Resonance (CMR) imaging provides a comprehensive assessment of cardiac structure and function but remains constrained by high acquisition costs and reliance on expert annotations, limiting the availability of large-scale labeled datasets. In contrast, electrocardiograms (ECGs) are inexpensive, widely accessible, and offer a promising modality for conditioning the generative synthesis of cine CMR. To this end, we propose ECGFlowCMR, a novel ECG-to-CMR generative framework that integrates a Phase-Aware Masked Autoencoder (PA-MAE) and an Anatomy-Motion Disentangled Flow (AMDF) to address two fundamental challenges: (1) the cross-modal temporal mismatch between multi-beat ECG recordings and single-cycle CMR sequences, and (2) the anatomical observability gap due to the limited structural information inherent in ECGs. Extensive experiments on the UK Biobank and a proprietary clinical dataset demonstrate that ECGFlowCMR can generate realistic cine CMR sequences from ECG inputs, enabling scalable pretraining and improving performance on downstream cardiac disease classification and phenotype prediction tasks.
Jan 28, 2026

Parametric and Generative Forecasts of EPEX Day\char45 Ahead Energy Market Curves

We propose two methodologies for modelling aggregated supply and demand curves in the EPEX SPOT Day\char45 Ahead market, emphasizing generative models as a way to recover distributional variability. The first is a low\char45 dimensional parametric representation that yields deterministic point forecasts; the second is a high\char45 dimensional order\char45 level representation that samples from a conditional distribution of plausible curves. Both model the full curve structure, enabling the analysis of price sensitivity, volume sensitivity, and price impact. The parametric representation uses plateau levels, elastic\char45 region boundaries, and polynomial coefficients, forecast with eXtreme Gradient Boosting. The main contribution is the generative representation, which uses price arrivals and volume\char45 increment marks and is implemented with conditional Denoising Diffusion Probabilistic Models. Using French EPEX data from 2021 to 2024, we evaluate both approaches through curve reconstruction and a price\char45 maker storage optimization problem. The parametric implementation provides a deterministic reference, while the diffusion\char45 based implementation produces distributions of plausible curves and achieves higher realized profits and smaller gaps to an oracle benchmark in the storage application.
Dec 17, 2025

NMIRacle: Multi-modal Generative Molecular Elucidation from IR and NMR Spectra

Molecular structure elucidation from spectroscopic data is a long-standing challenge in Chemistry, traditionally requiring expert interpretation. We introduce NMIRacle, a two-stage generative framework that builds upon recent paradigms in AI-driven spectroscopy with minimal assumptions. In the first stage, NMIRacle learns to reconstruct molecular structures from count-aware fragment representations, capturing both fragment identities and their occurrences. In the second stage, a spectral encoder maps input spectra (IR, 1H-NMR, 13C-NMR) into a latent embedding used to condition the pre-trained generator, which is fine-tuned for direct spectra-to-molecule generation. This formulation bridges fragment-level chemical modeling with spectral evidence, yielding accurate molecular predictions. Empirical results demonstrate that NMIRacle outperforms existing baselines on molecular elucidation, while maintaining robust performance across increasing levels of molecular complexity.
Dec 9, 2025

UniLayDiff: A Unified Diffusion Transformer for Content-Aware Layout Generation

Content-aware layout generation is a critical task in graphic design automation, focused on creating visually appealing arrangements of elements that seamlessly blend with a given background image. The variety of real-world applications makes it highly challenging to develop a single model capable of unifying the diverse range of input-constrained generation sub-tasks, such as those conditioned by element types, sizes, or their relationships. Current methods either address only a subset of these tasks or necessitate separate model parameters for different conditions, failing to offer a truly unified solution. In this paper, we propose UniLayDiff: a Unified Diffusion Transformer, that for the first time, addresses various content-aware layout generation tasks with a single, end-to-end trainable model. Specifically, we treat layout constraints as a distinct modality and employ Multi-Modal Diffusion Transformer framework to capture the complex interplay between the background image, layout elements, and diverse constraints. Moreover, we integrate relation constraints through fine-tuning the model with LoRA after pretraining the model on other tasks. Such a schema not only achieves unified conditional generation but also enhances overall layout quality. Extensive experiments demonstrate that UniLayDiff achieves state-of-the-art performance across from unconditional to various conditional generation tasks and, to the best of our knowledge, is the first model to unify the full range of content-aware layout generation tasks.
Dec 8, 2025

Demo: Generative AI helps Radiotherapy Planning with User Preference

Radiotherapy planning is a highly complex process that often varies significantly across institutions and individual planners. Most existing deep learning approaches for 3D dose prediction rely on reference plans as ground truth during training, which can inadvertently bias models toward specific planning styles or institutional preferences. In this study, we introduce a novel generative model that predicts 3D dose distributions based solely on user-defined preference flavors. These customizable preferences enable planners to prioritize specific trade-offs between organs-at-risk (OARs) and planning target volumes (PTVs), offering greater flexibility and personalization. Designed for seamless integration with clinical treatment planning systems, our approach assists users in generating high-quality plans efficiently. Comparative evaluations demonstrate that our method can surpasses the Varian RapidPlan model in both adaptability and plan quality in some scenarios.
Dec 4, 2025

LatentFM: A Latent Flow Matching Approach for Generative Medical Image Segmentation

Generative models have achieved remarkable progress with the emergence of flow matching (FM). It has demonstrated strong generative capabilities and attracted significant attention as a simulation-free flow-based framework capable of learning exact data densities. Motivated by these advances, we propose LatentFM, a flow-based model operating in the latent space for medical image segmentation. To model the data distribution, we first design two variational autoencoders (VAEs) to encode both medical images and their corresponding masks into a lower-dimensional latent space. We then estimate a conditional velocity field that guides the flow based on the input image. By sampling multiple latent representations, our method synthesizes diverse segmentation outputs whose pixel-wise variance reliably captures the underlying data distribution, enabling both highly accurate and uncertainty-aware predictions. Furthermore, we generate confidence maps that quantify the model certainty, providing clinicians with richer information for deeper analysis. We conduct experiments on two datasets, ISIC-2018 and CVC-Clinic, and compare our method with several prior baselines, including both deterministic and generative approach models. Through comprehensive evaluations, both qualitative and quantitative results show that our approach achieves superior segmentation accuracy while remaining highly efficient in the latent space.
Nov 26, 2025

LaGen: Towards Autoregressive LiDAR Scene Generation

Generative world models for autonomous driving (AD) are of great value in applications such as data augmentation, closed-loop simulation, and safety-critical scenario evaluation. Unlike the widely studied image modality, in this work we explore generative world models for LiDAR data. Existing generation methods for LiDAR predominantly focus on single frame generation or lack the capacity for interactive simulation, while existing prediction approaches require multiple frames of historical input and can only deterministically predict multiple frames at once. Both paradigms fail to support long-horizon interactive generation. To this end, we introduce LaGen, which, to the best of our knowledge is the first autoregressive framework capable of generating long-horizon LiDAR scenes in a frame-by-frame, interactive manner. LaGen is able to take a single-frame input as a starting point and effectively utilize bounding box information as conditions to generate high-fidelity 4D scene. In addition, we introduce a scene decoupling estimation module to enhance the model's interactive generation capability for object-level content, as well as a noise modulation module to mitigate error accumulation during long-horizon generation. We extensively evaluate LaGen's performance in controlled data generation and long-horizon scene generation on the nuScenes dataset. The experimental results demonstrate that LaGen achieves state-of-the-art performance, especially on later frames. The code is publicly available at: https://github.com/szzhou88/LaGen.
Nov 8, 2025

AD-DAE: Alzheimer's Disease Progression Modeling with Unpaired Longitudinal MRI using Diffusion Auto-Encoders

Generative modeling frameworks have emerged as an effective approach to capture high-dimensional image distributions from large datasets without requiring domain-specific knowledge, a capability essential for disease progression modeling. Recent generative approaches have attempted to capture progression by mapping images to a latent space and guiding representations to generate follow-up images from previous time points. However, these methods impose constraints on distribution learning, resulting in latent spaces with limited controllability for generating follow-up images without paired subject-specific longitudinal guidance. In order to enable controlled movements in the latent representational space and generate progression images from a previous time-point image without subject-specific guidance, we introduce a conditionable Diffusion Auto-encoder framework that forms a compact latent space capturing high-level semantics and providing means to control generation. Our approach leverages this latent space to condition and apply controlled shifts to the representations of previous time-point images by isolating progression and subject identity information for generating follow-up images. The shifts are implicitly guided by correlating with progression attributes and constraining to Alzheimer's disease specific regions, without paired longitudinal guidance. We validate the generations through image quality metrics, volumetric progression analysis, and downstream tasks in Alzheimer's disease datasets from different sources. This demonstrates the effectiveness of our approach for Alzheimer's progression modeling and longitudinal image generation.
Oct 28, 2025

Causal-Aware Tabular GANs with Reinforcement Learning

Existing tabular data generation methods primarily focus on matching statistical distributions between real and synthetic data, often overlooking the preservation of underlying causal relationships. As a result, generated samples may appear realistic while failing to maintain the causal structure required for reliable downstream analysis. We propose CA-GAN, a causal-aware generative framework for tabular data synthesis that explicitly incorporates causal knowledge into both the training and generation processes. CA-GAN first extracts a causal graph from real data to provide structural prior knowledge, then employs a graph-conditioned Conditional WGAN-GP whose sub-generators model variables according to their causal dependencies. More importantly, we introduce a reinforcement learning-based objective that treats causal graph discrepancy between real and synthetic data as a reward signal, enabling causal consistency to become an explicit optimization target during training rather than an implicit consequence of sampling order. Extensive experiments on 14 synthetic and real-world datasets demonstrate that CA-GAN consistently outperforms seven state-of-the-art baselines in causal preservation while achieving strong downstream utility, privacy preservation, and data quality. These results show that CA-GAN provides an effective and practical solution for generating high-quality synthetic tabular data that better respects underlying causal mechanisms.
Oct 25, 2025

Streaming Generation for Music Accompaniment

Music generation models can produce high-fidelity coherent accompaniment given complete audio input, but are limited to editing and loop-based workflows. We study real-time audio-to-audio accompaniment: as a model hears an input audio stream (e.g., a singer singing), it has to also simultaneously generate in real-time a coherent accompanying stream (e.g., a guitar accompaniment). In this work, we propose a model design considering inevitable system delays in practical deployment with two design variables: future visibility tft_f, the offset between the output playback time and the latest input time used for conditioning, and output chunk duration kk, the number of frames emitted per call. We train Transformer decoders across a grid of (tf,k)(t_f,k) and show two consistent trade-offs: increasing effective tft_f improves coherence by reducing the recency gap, but requires faster inference to stay within the latency budget; increasing kk improves throughput but results in degraded accompaniment due to a reduced update rate. Finally, we observe that naive maximum-likelihood streaming training is insufficient for coherent accompaniment where future context is not available, motivating advanced anticipatory and agentic objectives for live jamming.
Oct 18, 2025

Simulation-free Structure Learning for Stochastic Population Dynamics

Modeling dynamical systems and unraveling their underlying structural dependencies is central to many domains in the natural sciences. Various physical systems, such as those arising in cell biology, are inherently high-dimensional and stochastic in nature, and admit only partial, noisy state measurements. Our primary motivating setting is single-cell biology, where destructive measurements yield unpaired population snapshots rather than longitudinal trajectories of the same cells. This poses a significant challenge for addressing the problems of modeling the underlying dynamics and inferring the network structure of these systems. Existing methods are typically tailored either for structure learning or modeling dynamics at the population level, but are limited in their ability to address both problems together. In this work, we address both problems simultaneously: we present StructureFlow, a novel and principled simulation-free training approach for jointly learning the structure and stochastic population dynamics of physical systems. We showcase the utility of StructureFlow for the tasks of structure learning from interventions and dynamical (trajectory) inference of conditional population dynamics. We empirically evaluate our approach on high-dimensional synthetic systems, a set of biologically plausible simulated systems, and an experimental single-cell dataset. We show that StructureFlow can learn the structure of underlying systems while simultaneously modeling their conditional population dynamics --- a key step toward model-based mechanistic understanding of systems behavior.
Oct 11, 2025

Transport-Coupled Bayesian Flows for Molecular Graph Generation

Molecular graph generation (MGG) is essentially a multi-class generative task, aimed at predicting categories of atoms and bonds under strict chemical and structural constraints. However, many prevailing diffusion paradigms learn to regress numerical embeddings and rely on a hard discretization rule during sampling to recover discrete labels. This introduces a fundamental discrepancy between training and sampling. While models are trained for point-wise numerical fidelity, the sampling process fundamentally relies on crossing categorical decision boundaries. This discrepancy forces the model to expend efforts on intra-class variations that become irrelevant after discretization, ultimately compromising diversity, structural statistics, and generalization performance. Therefore, we propose TopBF, a unified framework that (i) performs MGG directly in continuous parameter distributions, (ii) learns graph-topological understanding through a Quasi-Wasserstein optimal-transport coupling under geodesic costs, and (iii) supports controllable, property-conditioned generation during sampling without retraining the base model. TopBF innovatively employs cumulative distribution function (CDF) to compute category probabilities induced by the Gaussian channel, thereby unifying the training objective with the sampling discretization operation. Experiments on QM9 and ZINC250k demonstrate superior structural fidelity and efficient generation with improved performance.
Oct 3, 2025

What Drives Compositional Generalization in Visual Generative Models? The Importance of Continuous Training Objectives

Compositional generalization, the ability to generate novel combinations of known concepts, is a key ingredient for visual generative models. Yet, not all mechanisms that enable or inhibit it are fully understood. In this work, we conduct a systematic study of which design choices critically determine compositional generalization in image and video generation. By isolating independent design axes, we identify two key factors strongly associated with compositional success: (i) whether the training objective operates on a discrete or continuous distribution, and (ii) the completeness of conditioning information about constituent factors during training. We also show that relaxing the discrete loss with an auxiliary continuous latent objective can partially recover compositional performance in discrete models like MaskGIT. Our findings, corroborated by diverse compositional tasks and preliminary evidence in world models and LLMs, motivate a shift toward continuous objectives for compositional generalization.
Sep 26, 2025

Discovering Phase Space Structure in Learned Hamiltonian Systems

Mechanics-inspired neural dynamical models improve interpretability and physical consistency, but they usually assume a known configuration space, fixed physical parameters, and deterministic prediction from a prescribed initial condition. We introduce Structured Phase Space GAN (SPS-GAN), a conditional generative model that learns structured dynamics from both Cartesian trajectories and video. SPS-GAN combines a port-Hamiltonian backbone with adversarial conditional generation, allowing conservative, dissipative, and forced systems to be represented in a single architecture. To infer latent mechanical structure from raw observations, we use a cyclic-coordinate loss that recovers both the system degrees of freedom and canonical coordinates without access to the true phase space. Experiments on simulated and real-world systems show that SPS-GAN improves trajectory accuracy over supervised dynamics baselines and video consistency over generative baselines, while consistently recovering the correct latent mechanical coordinates across observation modalities and dynamical regimes.
Sep 19, 2025

ArchesClimate: Probabilistic Decadal Ensemble Generation With Flow Matching

Internal variability is a dominant contributor to the uncertainty of predictions at the interannual to decadal timescale. A typical approach to separating the internal variability from forced climate responses is to generate large ensembles of simulations under different initial conditions. Due to the complexity of Earth System Models, generating these large ensembles is computationally expensive. In this work, we present ArchesClimate, a deep learning-based climate model emulator designed to reduce the cost of exploring internal variability at timescales ranging from monthly to decadal. ArchesClimate is trained on decadal hindcasts of the IPSL-CM6A-LR climate model. We train a flow matching model following ArchesWeatherGen, which we adapt to predict near-term climate. Once trained, the model generates states at a one-month lead time from the states of the two preceding months, and can be used to auto-regressively emulate climate model simulations. We show that for up to 10 years, these generations are stable and physically consistent. We also show that for several important climate variables, ArchesClimate generates simulations that are interchangeable with the IPSL model. This work suggests that climate model emulators could reduce the cost of generating large ensembles with climate models.
Sep 13, 2025

Privacy-Preserving Generation of Clinical Narratives from Medical Terminologies

In high-stakes domains such as healthcare, privacy concerns severely limit the use of real-world training data. Differentially private (DP) synthetic data offers a promising alternative with formal privacy guarantees, but achieving strong utility remains challenging for clinical note generation due to domain specificity and long-form text complexity. We present Term2Note, a method for synthesising full-length clinical notes under DP constraints. By structurally separating content and form, Term2Note generates section-wise note content conditioned on medical terms, with terms and notes privatised under separate DP constraints, and applies a DP quality maximiser to improve outputs. Experiments demonstrate that Term2Note produces synthetic notes with statistical properties closely aligned with real clinical notes, and that downstream models trained on these notes achieve performance comparable to those trained on real clinical data. Compared to existing DP text generation baselines, Term2Note substantially improves both fidelity and utility, without relying on label distribution assumptions, highlighting its effectiveness as a practical privacy-preserving alternative to real clinical notes.
Sep 2, 2025

Synthetic data for ratemaking: imputation-based methods vs adversarial networks and autoencoders

Actuarial ratemaking depends on high-quality data, yet access to such data is often limited by the cost of obtaining new data, privacy concerns, etc. In this paper, we explore synthetic-data generation as a potential solution to these issues. In addition to generative methods previously studied in the actuarial literature, we explore and benchmark another class of approaches based on Multivariate Imputation by Chained Equations (MICE). In a comparative study using an open-source dataset, MICE-based models are evaluated against other generative models like Variational Autoencoders and Conditional Tabular Generative Adversarial Networks. We assess how well synthetic data preserves the original marginal distributions of variables as well as the multivariate relationships among covariates. The consistency between Generalized Linear Models (GLMs) trained on synthetic data with GLMs trained on the original data is also investigated. Furthermore, we assess the ease of use of each generative approach and study the impact of generically augmenting original data with synthetic data on the estimation of GLMs for predicting claim counts. Our results highlight the potential of MICE-based methods in creating high-fidelity tabular data while offering lower implementation complexity compared to deep generative models.
Aug 5, 2025

SonicMaster: Towards Controllable All-in-One Music Restoration and Mastering

Music recordings often suffer from audio quality issues such as excessive reverberation, distortion, clipping, tonal imbalances, and a narrowed stereo image, especially when created in non-professional settings without specialized equipment or expertise. These problems are typically corrected using separate specialized tools and manual adjustments. In this paper, we introduce SonicMaster, the first unified generative model for music restoration and mastering that addresses a broad spectrum of audio artifacts with text-based control. SonicMaster is conditioned on natural language instructions to apply targeted enhancements, or can operate in an automatic mode for general restoration. To train this model, we construct the SonicMaster dataset, a large dataset of paired degraded and high-quality tracks by simulating common degradation types with nineteen degradation functions belonging to five enhancements groups: equalization, dynamics, reverb, amplitude, and stereo. Our approach leverages a flow-matching generative training paradigm to learn an audio transformation that maps degraded inputs to their cleaned, mastered versions guided by text prompts. Objective audio quality metrics demonstrate that SonicMaster significantly improves sound quality across all artifact categories. Furthermore, subjective listening tests confirm that listeners prefer SonicMaster's enhanced outputs over other baselines.
Aug 3, 2025

Imbalance-Robust and Sampling-Efficient Continuous Conditional GANs via Adaptive Vicinal Learning and Auxiliary Regularization

Recent advances in continuous conditional generative modeling, including Continuous conditional Generative Adversarial Network (CcGAN) and Continuous Conditional Diffusion Model (CCDM), estimate high-dimensional data distributions conditioned on scalar regression labels such as angles, ages, or temperatures. However, fixed-size vicinal training in CcGAN can be sensitive to non-uniform label densities, whereas CCDM relies on computationally expensive iterative sampling. To address these issues, we propose CcGAN-AVAR, an imbalance-aware extension of CcGAN that combines soft/hybrid adaptive vicinity with auxiliary discriminator-guided regularization. The adaptive vicinity constructs a label-dependent local radius according to the available samples around each target condition, and the multi-task discriminator supplies both a regression signal for label consistency and a density-ratio-estimation signal for distribution matching. We further provide a theoretical interpretation characterizing how adaptive vicinal weighting affects the local bias-variance behavior of the discriminator target, how hybrid truncation reduces objective-level cross-condition mixing, and how the density-ratio-based generator penalty approximates a Pearson Chi-square discrepancy up to the estimation error of the density-ratio branch. Extensive experiments on four datasets, including the newly constructed imbalanced RC-49-I, covering resolutions from 64x64 to 256x256 across eleven settings, demonstrate that CcGAN-AVAR obtains strong generation quality and label consistency while preserving the one-step sampling efficiency of GANs, achieving 300x--2000x faster inference than CCDM.
Aug 1, 2025

A Conditional GAN for Tabular Data Generation with Probabilistic Sampling of Latent Subspaces

The tabular form constitutes the standard way of representing data in relational database systems and spreadsheets. But, similarly to other forms, tabular data suffers from class imbalance, a problem that causes serious performance degradation in a wide variety of machine learning tasks. One of the most effective solutions dictates the usage of Generative Adversarial Networks (GANs) in order to synthesize artificial data instances for the under-represented classes. Despite their good performance, most of the proposed GAN models do not take into account the vector subspaces of the input samples in the real data space, leading to data generation in arbitrary locations. In addition, the class labels are handled in the same manner as the other categorical variables, so conditional sampling by class is rendered less effective. To overcome these problems, this study presents ctdGAN, a conditional GAN for alleviating class imbalance in tabular datasets. Initially, ctdGAN executes a space partitioning step to assign cluster labels to the input samples. Subsequently, it utilizes these labels to synthesize samples via a novel probabilistic sampling strategy and a new loss function that penalizes both cluster and class mis-predictions. In this way, ctdGAN generates samples in subspaces that resemble those of the original data distribution. We also introduce several other improvements, including a simple, yet effective cluster-wise scaling technique that captures multiple feature modes without affecting data dimensionality. The evaluation of ctdGAN with 14 imbalanced datasets demonstrated its strong ability in generating high fidelity samples and improving classification accuracy.
Jun 9, 2025

SIGNER: Temporally Grounded Sign Language Generation via Time-Resolved Conditioning

Sign language generation (SLG), also known as text-to-sign generation, aims to bridge the communication gap between signers and non-signers. Unlike many other generative tasks, SLG must satisfy two fundamental linguistic constraints. First, sign language expresses meaning through a sequence of gestures aligned with word-like units called glosses, and therefore requires correct lexical ordering to preserve intended meaning. Second, each gesture should faithfully reflect the intended gloss (semantic accuracy). Despite recent progress, existing SLG methods frequently produce signs with incorrect lexical order and low semantic accuracy. A common limitation of prior approaches stems from globally fused conditioning strategies, which weaken temporal grounding, the temporal correspondence between glosses and their realized sign segments. This often leads to incorrect lexical order and semantically ambiguous signs. To address this limitation, we propose SIGNER, a SIGN language generation framework with timE-Resolved conditioning to ensure temporal grounding, leveraging a temporal-gloss condition and local temporal fusion (LTF). SIGNER constructs a temporal-gloss condition by estimating a gloss sequence and its durations from input text, and assigning gloss semantics across the temporal dimension. We then introduce LTF, a temporally grounded fusion module that integrates the temporal-gloss condition within a constrained temporal window during denoising. By enforcing temporal locality in condition fusion, LTF preserves temporal grounding, leading to correct lexical ordering and clearer per-gloss semantics. Experiments on Phoenix-2014T and CSL-Daily demonstrate state-of-the-art performance, further supported by motion-smoothness analysis. The project page is available here https://taeryunglee.github.io/projects/signer.
Apr 24, 2025

OmegAMP: Targeted AMP Discovery via Biologically Informed Generation

Deep learning-based antimicrobial peptide (AMP) discovery faces critical challenges such as limited controllability, lack of representations that efficiently model antimicrobial properties, and low experimental hit rates. To address these challenges, we introduce OmegAMP, a framework designed for reliable AMP generation with increased controllability. Its diffusion-based generative model leverages a novel conditioning mechanism to achieve fine-grained control over desired physicochemical properties and to direct generation towards specific activity profiles, including species-specific effectiveness. This is further enhanced by a biologically informed encoding space that significantly improves overall generative performance. Complementing these generative capabilities, OmegAMP leverages a novel synthetic data augmentation strategy to train classifiers for AMP filtering, drastically reducing false positive rates and thereby increasing the likelihood of experimental success. Our in silico experiments demonstrate that OmegAMP delivers state-of-the-art performance across key stages of the AMP discovery pipeline, enabling us to achieve an unprecedented success rate in wet lab experiments. We tested 25 candidate peptides, 24 of them (96%) demonstrated antimicrobial activity, proving effective even against multi-drug resistant strains. Our findings underscore OmegAMP's potential to significantly advance computational frameworks in the fight against antimicrobial resistance.