Multimodal Classification

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23 papers in the last four weeks, up 360% on the four weeks before. 0.2% of all new papers.

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Latest papers 134

Jun 1, 2026cs.CL

FigSIM: A Dataset for Fine-grained Suicide Severity and Figurative Language in Suicide Memes

Suicide memes are memes used to express suicide-related thoughts or comment on suicide-related issues. Suicide memes are increasingly common on social media, yet remain poorly understood and potentially harmful. There is an urgent need to better understand their characteristics and to develop appropriate content moderation strategies that limits users' exposure to potentially harmful content. Currently, the absence of annotated datasets of suicide memes remains a key barrier to developing and evaluating automated moderation approaches. In this paper, we introduce FigSIM, the first dataset designed for fine-grained analysis of suicide memes. The dataset consists of 1049 memes, each annotated for (1) fine-grained suicide severity levels, (2) figurative phenomena (e.g., metaphors), and (3) suicide-related content (e.g., suicide method depiction). We benchmark 16 unimodal and multimodal models across three tasks: figurative language, suicide severity, and suicide-related content detection. Overall, FigSIM demonstrates that suicide memes pose unique challenges for both modeling and content moderation. Analysis revealed biases, such as underprediction of higher suicide severity levels, especially for figurative memes. The dataset (including splits used for analyses) is publicly available. Content Warning: This paper contains suicide-related content that may be triggering.

Liuliu Chen, Elise R. Carrotte, Brian E. Chapman +2

School of Computing and Information Systems, University of Melbourne, Australia · Orygen, The National Centre of Excellence in Youth Mental Health, Australia · Centre for Youth Mental Health, University of Melbourne, Australia +1

Figurative Language Understanding Social Media Analysis Multimodal Classification Content Moderation

Jun 1, 2026cs.CV

Multimodal Approaches for Visually-Rich Document Type Classification: A Comparative Analysis

Document type classification in visually rich documents remains challenging, as relevant information is distributed across textual, visual, and layout modalities. To capture this complexity, current approaches rely on diverse multimodal modeling strategies, resulting in heterogeneous architectures that complicate systematic comparison. This variability is also reflected in existing comparative studies, which often rely on heterogeneous evaluation setups, further complicating systematic comparison and making it difficult to assess progress. To address these limitations, this work provides a structured analysis of multimodal design strategies across transformer- and LLM-based architectures, combined with a controlled empirical comparison within a unified experimental framework. Specifically, four representative models (LayoutLMv3, Donut, Qwen3-VL-32B-Instruct, and Qwen3-32B) are evaluated on the RVL-CDIP benchmark to systematically analyze the contributions of text, image, and layout information for document type classification, with a particular focus on contrasting OCR-dependent and OCR-free approaches. The results show that specialized multimodal Transformers outperform LLM-based approaches on visually rich and layout-intensive documents. Image information contributes most strongly to reliable classification, while OCR-derived text provides useful but secondary support. These findings highlight that multimodal processing remains essential for documents with pronounced layout structure. Overall, the study provides a systematic basis for comparing multimodal architectures and offers practical guidance for selecting effective feature combinations and model designs for document type classification.

Catyana Heyne, Jürgen Frikel, Filippo Riccio

OTH Regensburg, Germany

Document Understanding Multimodal Classification Multimodal Model Evaluation Document Image Understanding

Jun 1, 2026cs.LG

When Tabular Foundation Models Transfer Across Modalities: A Systematic Evaluation Across 95 Datasets, 7 Modalities, and Two Regimes

We present a single classification pipeline that combines an Equiangular Tight Frame (ETF) preprocessing stage with a tabular foundation model for in-context inference, applied identically across modalities once data is mapped to fixed vector representations. We evaluate it on 95 datasets spanning seven signal modalities -- vision, audio, speech, text, molecular, time-series, and tabular. The main methodological contribution is to fix the comparison object: throughout the paper, performance is judged against the strongest lightweight tuned baseline on the same frozen features, while oracle selection, deployed selection, and specialized fine-tuning are reported separately. The pipeline is broadly competitive with strong lightweight tuned baselines on the same frozen features. It does not match the very best specialized models or heavily tuned pipelines on every task, but it stays close, and it runs much faster -- typically 4 to 200 times faster than full backbone fine-tuning, often at comparable quality. We describe how to deploy the pipeline in practice: when to apply ETF preprocessing, how to stop its training without a validation split, how to set up the in-context classifier, and how to calibrate the resulting probabilities. The calibration step is non-cosmetic: TabICL produces well-calibrated probabilities by construction, ETF preprocessing initially disrupts that calibration, and the post-hoc rescaling restores it -- yielding a per-prediction confidence signal that practitioners can use as a trust threshold for confidence-gated deployment. We also report where the pipeline should not be expected to help, and how to identify those cases in advance.

Julien Lafrance

Télécom Paris, Institut Polytechnique de Paris · Palaiseau, France

Cross-Modal Learning Tabular Foundation Models Multimodal Classification Tabular ICL

May 29, 2026cs.LG

SDM-Q: Cost-Aware Staged Decision-Making for Multi-Omics Classification with Deep Q-Learning

Multi-omics data provide complementary molecular characterizations of disease phenotypes and play an important role in disease diagnosis and subtype classification in precision medicine. However, acquiring complete multi-omics profiles is expensive and time-consuming, while most existing deep learning methods assume full modality availability during inference, resulting in substantial redundancy and limited practicality in clinical settings. To address this issue, we propose SDM-Q, a reinforcement learning framework for adaptive and cost-aware multi-omics classification. Specifically, multi-omics diagnosis is reformulated as a finite-horizon sequential decision problem, where the currently acquired omics modalities define the diagnostic state at each stage. An action--value function determines whether to acquire an additional modality or terminate the decision process and output the final prediction. To balance diagnostic utility and acquisition cost, the reward is defined only at the terminal stage and jointly determined by classification correctness and cumulative modality acquisition cost. A backward stage-wise optimization strategy is introduced to improve policy consistency and training stability. Experiments on four public multi-omics datasets, including ROSMAP, LGG, BRCA, and KIPAN, demonstrate that SDM-Q effectively reduces redundant modality acquisition while maintaining competitive classification performance compared with methods using complete multi-omics inputs. In the BRCA and KIPAN datasets, more than 99% and 95% of subjects, respectively, achieve accurate classification using only a single omics modality, while the average number of acquired modalities remains below two for ROSMAP and LGG. These results suggest that cost-aware sequential decision-making provides an effective paradigm for improving the efficiency of precision medicine workflows.

Nan Mu, Yangfan Xiao, Ling Wang +3

College of Computer Science, Sichuan Normal University, Chengdu, Sichuan 610101, China. · Department of Mathematics, College of Science and Mathematics, Kennesaw State University, Kennesaw, GA 30144, USA. · Department of Computer Science, College of Computing and Software Engineering, Kennesaw State University, Marietta, GA 30060, USA.

Cost-Sensitive Learning Deep Q-Learning Multimodal Classification

May 26, 2026cs.MM

MinhwaNet: Faithful but Insufficient Object Grounding in Korean Folk Painting

Korean folk painting (minhwa) is built from a small vocabulary of auspicious symbols, a tiger for protection, a pair of birds for marital harmony, a peony for wealth, that recur across many of its painted genres. This suggests an obvious computational approach, identify which symbols appear in a painting and read the genre from the inventory. Working with a public corpus that pairs whole paintings, eight-field bilingual curatorial captions, and a separate set of expert object crops, we find that this approach does not work. A model given only a list of which symbols a painting contains predicts the genre far worse than a model that fuses the image with the curatorial text, and forcing the genre representation to be object-grounded actively hurts accuracy. The visual evidence on which the genre prediction rests is nonetheless localized and inspectable. A leakage-safe object evidence map projected from a part-level detector is spatially faithful to where curators isolated symbolic objects and to a patch-based surrogate's own gradient saliency. We name this configuration a faithful-but-insufficient dissociation. The part-level explanation is honest about what the part-level model sees, yet the genre target turns on how symbols are arranged rather than on which ones appear. The same lens separates a content label that survives transfer to held-out source institutions, genre, from a style label that does not, era, a prediction we confirm on two further labels in the corpus. We release the multimodal system, a worked-example reading of one painting's evidence map against its catalogue, and a set of evaluation cautions that recur in long-tailed heritage collections.

Joonhyung Bae

Korea Advanced Institute of Science and Technology (KAIST), South Korea · Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea

Multimodal Grounding Multimodal Classification Cultural Heritage Image Classification

May 25, 2026cs.CV

Multi-Modal Building Inspection via Perceiver IO Fusion of Satellite and Street-Level Imagery

We present a multi-modal classification framework that fuses satellite and street-level imagery through a Perceiver IO architecture operating on spatial patch tokens from a shared DINOv2 backbone. The design naturally handles a variable number of street-level views per building without padding or fixed-size pooling, and jointly predicts multi-label roof element and roof material classes. We construct a large-scale dataset of 32,135 buildings (61,672 segments) spanning ten countries, pairing satellite images with up to eight street-level views per segment and evaluating four masking strategies for isolating the target building. We propose an RGB-M masking strategy that appends the building footprint mask as a fourth input channel, providing a soft spatial prior that outperforms hard cropping across both modalities. The Perceiver IO fusion model improves over all other fusion strategies and yields substantial per-class gains for attributes visible from street level (e.g., +11.3 AP for slate, +1.3 AP for dormers), though the satellite-only baseline retains a slight advantage in macro-averaged mAP for classes that are predominantly visible from above. These results establish a scalable, flexible architecture for multi-modal building inspection that can accommodate heterogeneous inputs and multiple output tasks.

Niels Sombekke, Rob G. J. Wijnhoven, Martin R. Oswald

University of Amsterdam (UvA), Amsterdam, The Netherlands · Spotr, The Hague, The Netherlands

Remote Sensing Image Understanding Multi-Source Image Fusion Multimodal Classification Multimodal Fusion Image Classification

May 23, 2026cs.AI

ConceptM $^3$ oE: Concept-Guided Multimodal Mixture of Experts for Interpretable Computational Pathology

Healthcare models are transitioning from unimodal prediction toward multimodal reasoning over heterogeneous diagnostic inputs. In computational pathology, for complex tumor subtypes where morphology alone can be challenging to distinguish, pathology reports and molecular measurements may provide additional diagnostic evidence alongside whole-slide images, yet existing models often fail to clarify how diverse signals assemble into recognizable diagnostic concepts. We propose ConceptM

^3

oE (Concept Multimodal MoE), which embeds concept formation directly within interaction-aware mixture-of-experts (MoE) pathways. The architecture decomposes evidence into modality-specific, redundant, and synergistic experts, which are then projected into structured concept bottlenecks mapping latent features to a hierarchy of morphology and biomarker concepts. To prevent the information loss typical of interpretable bottlenecks, we utilize residual pathways within each expert to allow task-relevant signals to flow both through the concepts and directly to the final task prediction, so that high performance is maintained alongside interpretability. Across an institutional pediatric brain tumor cohort and a public glioma cohort, the framework delivers competitive performance to unconstrained models while producing reasoning traces validated by an independent neuropathologist. In data-limited regimes, ConceptM

^3

oE improves limited-data performance, increasing macro-F1 from 56.41% to 66.70% at small training sizes compared to non-concept-informed baselines, while also showing faster training convergence consistent with the regularizing effect of concept learning. This work offers a scalable path toward high-performance medical AI that is inherently verifiable and better aligned with the complex decision-making of clinical practice.

Xuan Wang, Zhongling Xu, Gopi Kannedhara +13

University of Texas at Austin, Austin, TX, USA · University of North Carolina at Chapel Hill, NC, USA · Dell Children’s Medical Center, Austin, TX, USA +2

Computational Pathology Concept Bottleneck Models Healthcare Interpretable ML Multimodal Classification Oncology+4

May 20, 2026cs.LG

Modular Multimodal Classification Without Fine-Tuning: A Simple Compositional Approach

We introduce CoMET, \textit{\textbf{C}omposing \textbf{M}odality \textbf{E}ncoders with \textbf{T}abular foundation models}, a simple yet highly competitive method for multimodal classification: pass each modality through a frozen pre-trained backbone, compress the resulting embeddings with PCA, and concatenate as input into a Tabular Foundation Model (TFM) for prediction. We show that PCA alone suffices to act as an adaptor yielding strong, robust performance across modalities. When the \texttt{CLS} tokens of the foundation model align poorly with downstream tasks, we propose \textbf{PALPooling}, a lightweight adaptive token pooler that consistently improves representation quality. By composing strong frozen representation learning backbones with TFMs, our approach achieves state-of-the-art results across diverse multimodal benchmarks without any training. On hierarchical tasks with large fine-grained class spaces, our approach enables fast and scalable classification, handling datasets with over 500,000 samples and 2,000 classes without any fine-tuning. Overall, our results show that the composition of foundation models is a simple, yet powerful, out-of-the-box solution for multimodal learning, challenging the necessity of complex, end-to-end training pipelines for new problems.

Herman Bergström, Aditya Mehrotra, Rahul G. Krishnan

Chalmers University of Technology and University of Gothenburg · Vector Institute · University of Toronto

Multimodal Embedding Multimodal Classification Multimodal Foundation Models Multimodal Learning Multimodal Understanding

May 20, 2026cs.CV

QwenSafe: Multimodal Content Rating Description Identification via Preference-Aligned VLMs

Mobile app marketplaces require developers to disclose standardized content rating descriptors (CRDs) to inform users about potentially sensitive or restricted content. Ensuring the accuracy and consistency of these disclosures remains challenging due to the multimodal nature of app content, which spans textual descriptions and visual interfaces. In this paper, we present QwenSafe, a Vision-Language Model (VLM) designed to automatically identify the presence of Apple-defined CRDs by jointly reasoning over app metadata and screenshots. To enable scalable training for this task, we introduce metadata2CRD, a data-construction pipeline that synthesizes descriptor-aligned question-answer pairs by combining app descriptions, screenshots, and formal descriptor definitions. We adapt Qwen3-VL-8B using supervised fine-tuning followed by Direct Preference Optimization (DPO) to align model predictions with descriptor-specific evidence and explanations across visual and textual modalities. We evaluate QwenSafe on 12 Apple-defined content rating descriptors and compare it against state-of-the-art vision-language models, including Qwen3-VL, LLaVA-1.6, and Gemini-2.5-Flash. QwenSafe consistently outperforms all baselines in binary CRD classification, achieving improvements in positive-class recall of 111.8%, 36.1%, and 2.1%, respectively. Our results demonstrate that descriptor-aware multimodal alignment substantially improves automated content classification and highlights the potential of vision-language models to support scalable and consistent content rating in mobile app marketplaces.

Dishanika Denipitiyage, Aruna Seneviratne, Suranga Seneviratne

University of Sydney, Sydney, Australia · University of New South Wales, Australia

Multimodal Classification

May 18, 2026cs.CV

CodeBind: Decoupled Representation Learning for Multimodal Alignment with Unified Compositional Codebook

Multimodal representation alignment is pivotal for large language models and robotics. Traditional methods are often hindered by cross-modal information discrepancies and data scarcity, leading to suboptimal alignment spaces that overlook modality-unique features. We propose CodeBind, a framework that optimizes multimodal representation spaces through a modality-shared-specific codebook design. By incrementally aligning target and bridging modalities, CodeBind bypasses the need for fully paired data. Unlike traditional hard alignment, CodeBind decomposes features into shared components for semantic consistency and specific components for modality-unique details. This design utilizes a compositional vector quantization scheme, where a shared codebook bridges modality gaps and modality-specific codebooks mitigate representation bias by preventing dominant modalities from overshadowing others. Validated across nine modalities (text, image, video, audio, depth, thermal, tactile, 3D point cloud, EEG), CodeBind achieves state-of-the-art performance in multimodal classification and retrieval tasks.

Zeyu Chen, Jie Li, Kai Han

Visual AI Lab, The University of Hong Kong

Cross-Modal Learning Multimodal Disentangled Representation Learning Cross-Modal Alignment Cross-Modal Retrieval Multimodal Classification Multimodal Learning

May 16, 2026cs.AI

A Conflict-aware Evidential Framework for Reliable Sleep Stage Classification

Multi-view learning has been widely applied for sleep stage classification using multi-modal data. However, existing methods typically assume that different modalities are well-aligned, which is often unattainable in real-world scenarios, thereby compromising the reliability of the staging results. In this paper, we propose ConfSleepNet, a conflict-aware evidential framework that dynamically resolves inter-view conflicts. The framework consists of multi-view evidence extraction and conflict-aware aggregation. In the first phase, it learns category-related evidence from different modalities, which represents the degree of support for individual sleep stages. Considering the inherent characteristics of varying modalities, we propose hybrid category structures for different modalities to promote more reasonable evidence learning. In the second phase, view-specific opinions, including prediction results and uncertainty, are constructed from the learned evidence. Notably, we propose a novel conflict-aware aggregation method that integrates these view-specific opinions into a reliable joint decision. This mechanism can effectively resolve conflicts among opinions and synthesize them into a reliable joint decision. Both theoretical analysis and experimental results demonstrate the effectiveness of ConfSleepNet in sleep staging tasks. The code is available at https://github.com/By4te/ConfSleepNet_ICML2026/.

Yunzhi Tian, Dekui Wang, Qirong Bu +3

College of Computer Science, Northwest University, Xi’an, China.

Sleep Stage Classification Evidential Deep Learning Time Series Classification Multi-View Learning Multimodal Classification Multimodal Fusion

May 15, 2026cs.LG

DeepArrhythmia: Segment-Contextualized ECG Arrhythmia Classification via Selective Evidence Acquisition

Beat-level Electrocardiography (ECG) arrhythmia detection aims to assign an arrhythmia class to each beat in a recording, yet many existing systems treat beats as isolated local instances. This is limiting because beat labels often depend on multi-beat rhythm context, including timing, compensatory pauses, and beat-to-beat morphological consistency. We present DeepArrhythmia, a tool-grounded multimodal framework for segment-contextualized beat-level ECG arrhythmia classification. Given a multi-beat ECG segment, DeepArrhythmia combines the raw ECG signal and a rendered waveform image, localizes R peaks to identify beat instances, and produces structured beat-level predictions. The framework decouples physiological measurement from evidence integration using specialized tools for beat localization, numerical rhythm--morphology extraction, and morphology-focused textual analysis. DeepArrhythmia uses segment-level confidence to route between minimal and rich evidence states, since richer physiological evidence is not uniformly useful. This agentic design integrates rhythm context, explicit physiological grounding, and selective evidence acquisition for decision making.

Jiahui Li, Ruili Fang, Zishuai Liu +3

University of Georgia

Electrocardiography Multimodal Classification Electrocardiogram Classification

May 13, 2026cs.LG

Machine Learning-Driven Multimodal Spectroscopic Liquid Biopsy for Early Multicancer Detection

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy has emerged as a promising alternative, as it enables the holistic characterization of biochemical alterations in biological fluids. In this work, we propose a multimodal spectroscopic liquid biopsy framework for multicancer detection based on the combination of Fourier Transform Infrared (FTIR) spectroscopy, Raman spectroscopy, and Excitation-Emission Matrix (EEM) fluorescence spectroscopy together with Machine Learning (ML) methodologies. Serum samples from breast cancer patients, colorectal cancer patients, and healthy controls were analyzed through the three spectroscopic modalities. After modality-specific preprocessing, low-level data fusion (LLDF) was employed to integrate the complementary biochemical information encoded within the different spectroscopic measurements, and classification was performed using XGBoost models. Seven experimental configurations were evaluated, including the three unimodal approaches, all pairwise bimodal configurations, and the full multimodal approach of FTIR, Raman, and EEM fluorescence. The results show that although several individual modalities achieved high discrimination performance, the multimodal fusion provided the most balanced overall results, reaching a ROC-AUC of 0.997 for breast cancer and 0.994 for colorectal cancer, together with highly balanced sensitivity and specificity values.

Alejandro Leonardo García Navarro, Javier Cachón Ortiz, Javier González Colsa +2

Signal Processing Group Gregorio Marañón Health Research Institute Madrid, Spain · Amber Health Solutions Madrid, Spain

Multimodal Classification Oncology Multimodal Fusion

May 12, 2026cs.LG

Resilient Vision-Tabular Multimodal Learning under Modality Missingness

Multimodal deep learning has shown strong potential in medical applications by integrating heterogeneous data sources such as medical images and structured clinical variables. However, most existing approaches implicitly assume complete modality availability, an assumption that rarely holds in real-world clinical settings where entire modalities and individual features are frequently missing. In this work, we propose a multimodal transformer framework for joint vision-tabular learning explicitly designed to operate under pervasive modality missingness, without relying on imputation or heuristic model switching. The architecture integrates three components: a vision, a tabular, and a multimodal fusion encoder. Unimodal representations are weighted through learnable modality tokens and fused via intermediate fusion with masked self-attention, which excludes missing tokens and modalities from information aggregation and gradient propagation. To further enhance resilience, we introduce a modality-dropout regularization strategy that stochastically removes available modalities during training, encouraging the model to exploit complementary information under partial data availability. We evaluate our approach on the MIMIC-CXR dataset paired with structured clinical data from MIMIC-IV for multilabel classification of 14 diagnostic findings with incomplete annotations. Two parallel systematic stress-test protocols progressively increase training and inference missingness in each modality separately, spanning fully multimodal to fully unimodal scenarios. Across all missingness regimes, the proposed method consistently outperforms representative baselines, showing smoother performance degradation and improved robustness. Ablation studies further demonstrate that attention-level masking and intermediate fusion with joint fine-tuning are key to resilient multimodal inference.

Camillo Maria Caruso, Valerio Guarrasi, Paolo Soda

Research Unit of Artificial Intelligence and Computer Systems, Department of Engineering, Università Campus Bio-Medico di Roma, Roma, Italy, Europe · Department of Diagnostics and Intervention, Radiation Physics, Biomedical Engineering, Umeå University, Umeå, Sweden, Europe

Missing-Modality Learning Multimodal Robustness Multimodal Classification Multimodal Fusion Multimodal Learning

May 11, 2026cs.CL

Multi-domain Multi-modal Document Classification Benchmark with a Multi-level Taxonomy

Document classification forms the backbone of modern enterprise content management, yet existing benchmarks remain trapped in oversimplified paradigms -- single domain settings with flat label structures -- that bear little resemblance to the hierarchical, multi-modal, and cross-domain nature of real-world business documents. This gap not only misrepresents practical complexity but also stifles progress toward industrially viable document intelligence. To bridge this gap, we construct the first Multi-level, Multi-domain, Multi-modal document classification Benchmark (MMM-Bench). MMM-Bench includes (1) a deeply hierarchical taxonomy spanning five levels that capture the authentic organizational logic of business documentation; and (2) 5,990 real-world multi-modal documents meticulously curated from 12 commercial domains in Alibaba. Each document is manually annotated with a complete hierarchical path by domain experts. We establish comprehensive baselines on MMM-Bench, which consists of open-weight models and API-based models. Through systematic experiments, we identify four fundamental challenges within MMM-Bench and propose corresponding insights. To provide a solid foundation for advancing research in multi-level, multi-domain document classification, we release all of the data and the evaluation toolkit of MMM-Bench at https://github.com/MMMDC-Bench/MMMDC-Bench.

Denghao Ma, Qing Liu, Zulong Chen +5

Beijing Information Science and Technology University, China · Alibaba Group, China · Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), China +2

Hierarchical Classification Text Classification Multimodal Classification Classification

May 11, 2026cs.CV

Simultaneous Long-tailed Recognition and Multi-modal Fusion for Highly Imbalanced Multi-modal Data

Long-tailed distributions in class-imbalanced data present a fundamental challenge for deep learning models, which tend to be biased toward majority classes. While recent methods for long-tailed recognition have mitigated this issue, they are largely restricted to single-modal inputs and cannot fully exploit complementary information from diverse data sources. In this work, we introduce a new framework for long-tailed recognition that explicitly handles multi-modal inputs. Our approach extends multi-expert architectures to the multi-modal setting by fusing heterogeneous data into a unified representation while leveraging modality-specific networks to estimate the informativeness of each modality. These confidence-guided weights dynamically modulate the fusion process, ensuring that more informative modalities contribute more strongly to the final decision. To further enhance performance, we design specialized training and test procedures that accommodate diverse modality combinations, including images and tabular data. Extensive experiments on benchmark and real-world datasets demonstrate that the proposed approach not only effectively integrates multi-modal information but also outperforms existing methods in handling long-tailed, class-imbalanced scenarios, highlighting its robustness and generalization capability.

Heegeon Yoon, Heeyoung Kim

Department of Industrial and Systems Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea

Class-Imbalanced Learning Long-Tailed Classification Multimodal Classification Multimodal Fusion

May 9, 2026cs.LG

Learning predictive models for combinations of heterogeneous proteomic data sources

Multiple technologies that measure expression levels of protein mixtures in the human body offer a potential for detection and understanding the disease. The recent increase of these technologies prompts researchers to evaluate the individual and combined utility of data generated by the technologies. In this work, we study two data sources to measure the expression of protein mixtures in the human body: whole-sample MS profiling and multiplexed protein arrays. We investigate the individual and combined utility of these technologies by learning and testing a variety of classification models on the data from a pancreatic cancer study. We show that for the combination of these two (heterogeneous) datasets, classification models that work well on one of them individually fail on the combination of the two datasets. We study and propose a class of model fusion methods that acknowledge the differences and try to reap most of the benefits from their combination.

Michal Valko, Richard Pelikan, Miloš Hauskrecht

Computer Science Department University of Pittsburgh, Pittsburgh, Pennsylvania

Medical Diagnosis Multimodal Classification Multimodal Fusion

May 8, 2026cs.CV

Multimodal Stepwise Clinically-Guided Attention Learning for Pathological Complete Response Prediction in Breast Cancer

Pathological complete response (pCR) is a key prognostic factor in breast cancer patients undergoing neoadjuvant therapy, strongly associated with long-term survival and treatment personalization. However, accurate pre-treatment pCR prediction remains challenging due to severe class imbalance and limited generalizability across diverse clinical settings. In this work, we propose a multimodal stepwise clinically-guided attention learning framework for pCR prediction from breast magnetic resonance imaging (MRI), designed to address these limitations through medically grounded spatial guidance and multimodal integration. The approach follows a stepwise training strategy inspired by physician reasoning: the model first learns global discriminative imaging patterns, then attention mechanisms are introduced to constrain the network toward tumor regions, and finally clinical variables are integrated to refine decision-making. This guidance strategy encourages prioritization of task-relevant features, improving identification of responders despite their limited representation in the dataset. Moreover, grounding attention in anatomically consistent tumor regions reduces reliance on dataset-specific patterns, thereby enhancing cross-institutional generalization. The framework is evaluated through external validation across heterogeneous MRI cohorts. Compared to non-guided single-stage baselines, the proposed approach improves sensitivity while maintaining competitive specificity, and produces anatomically coherent attention maps that support interpretation of the model's predictions. These findings highlight the potential of clinically-guided multimodal attention learning for robust and generalizable pCR prediction in breast cancer.

Alice Natalina Caragliano, Valerio Guarrasi, Michela Gravina +2

Unit of Artificial Intelligence and Computer Systems, Department of Engineering, Università Campus Bio-Medico di Roma, Rome, Italy · Department of Electrical Engineering and Information Technology, University of Naples Federico II, Naples, Italy · Department of Diagnostics and Intervention, Radiation Physics, Biomedical Engineering, Umeå University, Umeå, Sweden

Breast Cancer Clinical Outcome Prediction Multimodal Classification Oncology Explainable Medical Image Analysis

May 7, 2026stat.ML

Multimodal Deep Generative Model for Semi-Supervised Learning under Class Imbalance

When modeling class-imbalanced data, it is crucial to address the imbalance, as models trained on such data tend to be biased towards the majority classes. This problem is amplified under partial supervision, where pseudo-labels for unlabeled data are predicted based on imbalanced labeled data, propagating the bias. While recent semi-supervised models address class imbalance, they typically assume single-modal input data. However, with the growing availability of multimodal data, it is essential to leverage complementary modalities. In this article, we propose a multimodal deep generative model for semi-supervised learning under class imbalance. Our approach uses separate encoders for each modality, sharing latent variables across modalities, and simplifies joint posterior computation with a product-of-experts method. To further address class imbalance, we replace typical Gaussian distributions with Student's t-distributions for the prior, encoder, and decoder, better capturing the heavy-tailed latent distributions in imbalanced data. We derive a new objective function for training the proposed model on both labeled and unlabeled data using

γ

-power divergence. Empirical results on benchmark and real-world datasets demonstrate that our model outperforms baseline methods in generalization, achieving superior classification performance for partially labeled multimodal data with imbalanced class distributions.

Heegeon Yoon, Heeyoung Kim

Department of Industrial and Systems Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea

Variational Autoencoders Class-Imbalanced Learning Multimodal Classification Semi-Supervised Learning

May 4, 2026cs.CV

Virtual Scanning for NSCLC Histology: Investigating the Discriminatory Power of Synthetic PET

Accurate histological differentiation between adenocarcinoma (ADC) and squamous cell carcinoma (SCC) is critical for personalized treatment in non-small cell lung cancer (NSCLC). While [

^{18}

F]FDG PET/CT is a standard tool for the clinical evaluation of lung cancer, its utility is often limited by high costs and radiation exposure. In this paper, we investigate the feasibility of "virtual scanning" as a feature-enhancement strategy by evaluating whether synthetic PET data can provide complementary feature representations to supplement anatomical CT scans in histological subtype classification. We propose a framework that leverages a 3D Pix2Pix Generative Adversarial Network (GAN), pretrained on the FDG-PET/CT Lesions dataset, to synthesize pseudo-PET volumes from anatomical CT scans. These synthetic volumes are integrated with structural CT data within the MINT framework, a multi-stage intermediate fusion architecture. Our experiments, conducted on a multi-center dataset of 714 subjects, demonstrate that the inclusion of synthetic metabolic features significantly improves classification performance over a CT-only baseline. The multimodal approach achieved a statistically significant increase in the Area Under the Curve (AUC) from 0.489 to 0.591 and improved the Geometric Mean (GMean) from 0.305 to 0.524. These results suggest that synthetic PET scans provide discriminatory metabolic cues that enable deep learning models to exploit complementary cross-modal information, offering a potential feature-enhancement strategy for clinical scenarios where physical PET scans are unavailable.

Fatih Aksu, Laura Ciuffetti, Francesco Di Feola +6

Università Campus Bio-Medico di Roma · Umeå University · Università Vita-Salute San Raffaele

PET/CT Imaging Multimodal Classification Medical Image Synthesis

May 1, 2026cs.LG

From Static Analysis to Audience Dissemination: A Training-Free Multimodal Controversy Detection Multi-Agent Framework

Multimodal controversy detection (MCD) identifies controversial content in videos and their associated user comments, to support risk management for social video platforms.Prior research frames MCD as a static representation learning task, where features are directly extracted from videos and their accompanying comments. However, these methods fail to capture the diverse perspectives and evaluations from different audience groups. Inspired by the real-world process of content dissemination among audiences, we propose AuDisAgent, a training-free multi-agent framework that reformulates MCD as a dynamic propagation process.Our framework explicitly models audience dissemination through a structured multi-agent system. First, three specialized Screening Agents (Video Agent, Comment Agent, and Interaction Agent) conduct initial assessments from visual, textual, and cross-modal perspectives, respectively. For samples where the three agents cannot reach a consensus, a Viewing Panel Agent is activated to simulate post-screening discussions among audiences with diverse backgrounds and stances. This mechanism models how different audience groups interpret and react to the same content, uncovering latent controversial content that may emerge during the dissemination process. Finally, an Arbitration Agent renders the final judgment based on the complete reasoning chain from the preceding steps.In addition, to address the "cold-start" scenario where newly released videos have few or no comments, we design a Comment Bootstrapping Strategy that leverages historical public comments from semantically similar videos as the initial comment context. Extensive experiments on a public dataset demonstrate that our framework significantly outperforms existing state-of-the-art (SOTA) methods in both rich-comment and limited-comment scenarios.

Zihan Ding, Ziyuan Yang, Yi Zhang

Sichuan University, Chengdu, Sichuan, China · Nanyang Technological University, Singapore

Social Media Analysis Multimodal Classification Multimodal Agents

Apr 30, 2026cs.AI

MM-StanceDet: Retrieval-Augmented Multi-modal Multi-agent Stance Detection

Multimodal Stance Detection (MSD) is crucial for understanding public discourse, yet effectively fusing text and image, especially with conflicting signals, remains challenging. Existing methods often face difficulties with contextual grounding, cross-modal interpretation ambiguity, and single-pass reasoning fragility. To address these, we propose Retrieval-Augmented Multi-modal Multi-agent Stance Detection (MM-StanceDet), a novel multi-agent framework integrating Retrieval Augmentation for contextual grounding, specialized Multimodal Analysis agents for nuanced interpretation, a Reasoning-Enhanced Debate stage for exploring perspectives, and Self-Reflection for robust adjudication. Extensive experiments on five datasets demonstrate MM-StanceDet significantly outperforms state-of-the-art baselines, validating the efficacy of its multi-agent architecture and structured reasoning stages in addressing complex multimodal stance challenges.

Weihai Lu, Zhejun Zhao, Yanshu Li +1

Peking University · Baidu Inc · Brown University +1

Multimodal Reasoning Multimodal Classification Multimodal Agents

Apr 30, 2026cs.CV

JI-ADF: Joint-Individual Learning with Adaptive Decision Fusion for Multimodal Skin Lesion Classification

Skin lesion classification is essential for early dermatological diagnosis, yet many existing computer-aided systems rely primarily on dermoscopic images and underutilize the multimodal evidence routinely available in clinical practice. To address this gap, we propose \textbf{JI-ADF}, a trimodal deep learning framework that integrates dermoscopic images, clinical photographs, and structured patient metadata for clinically grounded skin lesion classification. The proposed architecture combines joint multimodal representation learning with modality-specific auxiliary supervision and an adaptive decision fusion mechanism that dynamically calibrates modality contributions on a per-sample basis. To enhance cross-modal reasoning while preserving modality-specific evidence, we further introduce a multimodal fusion attention (MMFA) module. We evaluate JI-ADF on the large-scale MILK10k benchmark, which reflects real-world clinical acquisition conditions and severe class imbalance. The proposed method demonstrates strong and well-balanced performance across lesion categories, improving sensitivity and Dice score while maintaining high specificity and good calibration. Extensive analyses, including modality ablation, calibration evaluation, and Grad-CAM visualization, further confirm the robustness and clinically meaningful behavior of the model. These results indicate that JI-ADF provides a reliable and practical foundation for multimodal skin lesion classification in real-world clinical settings.

Phan Nguyen, Dat Cao, Hien Kha +4

1KAIST · 2Taipei Medical University · 3Yale University

Skin Lesion Classification Medical Diagnosis Multimodal Classification Medical Image Classification Multimodal Fusion

Apr 29, 2026cs.CV

VTBench: A Multimodal Framework for Time-Series Classification with Chart-Based Representations

Time-series classification (TSC) has advanced significantly with deep learning, yet most models rely solely on raw numerical inputs, overlooking alternative representations. While texture-based encodings such as Gramian Angular Fields (GAF) and Recurrence Plots (RP) convert time series into 2D images, they often require heavy preprocessing and yield less intuitive representations. In contrast, chart-based visualizations offer more interpretable alternatives and show promise in specific domains; however, their effectiveness remains underexplored, with limited systematic evaluation across chart types, visual encoding choices, and datasets. In this work, we introduce VTBench, a systematic and extensible framework that re-examines TSC through multimodal fusion of raw sequences and chart-based visualizations. VTBench generates lightweight, human-interpretable plots -- line, area, bar, and scatter, providing complementary views of the same signal. We develop a modular architecture supporting multiple fusion strategies, including single-chart visual-numerical fusion, multi-chart visual fusion, and full multimodal fusion with raw inputs. Through experiments across 31 UCR datasets, we show that: (1) chart-only models are competitive in selected settings, particularly on smaller datasets; (2) combining multiple chart types can improve accuracy by capturing complementary visual cues; and (3) multimodal models improve or maintain performance when visual features provide non-redundant information, but may degrade accuracy when they introduce redundancy. We further distill practical guidelines for selecting chart types, fusion strategies, and configurations. VTBench establishes a unified foundation for interpretable and effective multimodal time-series classification.

Madhumitha Venkatesan, Xuyang Chen, Dongyu Liu

University of California, Davis Davis, United States

Data Visualization Time Series Classification Multimodal Classification Multimodal Fusion Time Series Representation Learning

Apr 29, 2026cs.CV

A Multimodal Pre-trained Network for Integrated EEG-Video Seizure Detection

Reliable seizure detection in mouse models is essential for preclinical epilepsy research, yet manual review of synchronized video-EEG recordings is labor-intensive and single-modality systems fail for complementary reasons: video-based methods are easily confounded by benign behaviors, whereas EEG-based methods are vulnerable to ictal motion artifacts. We present EEGVFusion, a multimodal framework that combines self-supervised EEG representation learning, spatio-temporal video encoding, optimal-transport alignment, and bidirectional cross-attention to integrate neural and behavioral evidence. We also curate an expert-annotated dataset of synchronized EEG and video recordings comprising 93 sessions from 15 mice for training and evaluation. In the random-session split, EEGVFusion achieved a Balanced Accuracy of 0.9957 with perfect event sensitivity and an Event FAR of 0.6250 FP/h, indicating strong seizure detection performance with a low false-alarm burden. In a single held-out-subject evaluation with Subject 110 reserved for testing, EEGVFusion achieved a Balanced Accuracy of 0.9718 and reduced Event FAR from 2.7250 FP/h for the EEG-only counterpart to 0.4833 FP/h while preserving perfect event sensitivity. Targeted ablations further showed that EEG pre-training and OT alignment help reduce false alarms while preserving event sensitivity.

Tong Lu, Ke Xu, Zimo Zhang +12

Beijing Institute for Brain Research, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 102206, China · Chinese Institute for Brain Research, Beijing, Beijing, 102206, China · Department of Neurosurgery, SanBo Brain Hospital, Capital Medical University, Beijing, 100018, China +4

Electroencephalography EEG Seizure Detection Multimodal Pretraining Multimodal Classification Multimodal Fusion

Apr 29, 2026cs.SD

ASR-Agnostic Multimodal Spectrotemporal Modeling for Early Dementia Detection

Speech recruits the same executive, attentional, and working memory processes underlying instrumental activities of daily living, or IADLs, providing a non-invasive proxy for cognitive assessment. Yet most speech-based dementia detection systems depend on transcription, discard within-recording temporal structure, and are validated on a single English corpus with known recording artifacts. We propose an ASR-agnostic framework operating directly on Mel spectrograms. Our key contribution is extracting spectrotemporal displacement fields from consecutive spectrogram frames, capturing shifting spectral energy patterns as digital biomarkers of cognitive decline. These features are fused with CNN-ConvGRU acoustic embeddings via a learned cross-attention mechanism and aggregated using a Transformer encoder with learnable query pooling. A composite temporal loss enforces smoothness and contrastive coherence across segments. We train independent models on English DementiaBank, Slovak EWA-DB, and Spanish Ivanova corpora, using clinical elicitation protocols taxing IADL-relevant cognitive domains. The Slovak model achieves 83.9% accuracy, and Spanish achieves, while the English baseline yields 53.2%, confirming known artifacts. Cross-lingual ablation studies reveal distinct fusion regimes: removing cross-attention collapses Spanish performance to 53.7%, below unimodal models, while the Slovak audio encoder alone outperforms the full model, 93.7% vs. 83.9%, and all English configurations remain near chance. Thus, multimodal fusion's value is corpus-dependent: essential when signal is distributed across modalities, counterproductive when one dominates, and irrelevant when no signal exists. Auxiliary temporal losses converge to language-invariant values, indicating cross-lingual architectural stability.

Chukwuemeka Ugwu, Oluwafemi Richard Oyeleke

Speech-Based Dementia Detection Speech Processing Audio Understanding Multimodal Classification

Apr 25, 2026cs.CL

DARC-CLIP: Dynamic Adaptive Refinement with Cross-Attention for Meme Understanding

Memes convey meaning through the interaction of visual and textual signals, often combining humor, irony, and offense in subtle ways. Detecting harmful or sensitive content in memes requires accurate modeling of these multimodal cues. Existing CLIP-based approaches rely on static fusion, which struggles to capture fine grained dependencies between modalities. We propose DARC-CLIP, a CLIP-based framework for adaptive multimodal fusion with a hierarchical refinement stack. DARC-CLIP introduces Adaptive Cross-Attention Refiners to for bidirectional information alignment and Dynamic Feature Adapters for task-sensitive signal adaptation. We evaluate DARC-CLIP on the PrideMM benchmark, which includes hate, target, stance, and humor classification, and further test generalization on the CrisisHateMM dataset. DARC-CLIP achieves highly competitive classification accuracy across tasks, with significant gains of +4.18 AUROC and +6.84 F1 in hate detection over the strongest baseline. Ablation studies confirm that ACAR and DFA are the main contributors to these gains. These results show that adaptive cross-signal refinement is an effective strategy for multimodal content analysis in socially sensitive classification.

Qiyuan Jin

The Hong Kong University of Science and Technology

VLM Adaptation Hate Speech Detection Multimodal Classification Cross-Modal Attention Multimodal Fusion

Apr 19, 2026cs.LG

STEP-PD: Stage-Aware and Explainable Parkinson's Disease Severity Classification Using Multimodal Clinical Assessments

Parkinson's disease (PD) is a progressive disorder in which symptom burden and functional impairment evolve over time, making severity staging essential for clinical monitoring and treatment planning. However, many computational studies emphasize binary PD detection and do not fully use repeated follow-up clinical assessments for stage-aware prediction. This study proposes STEP-PD, a severity-aware machine learning framework to classify PD severity using clinically interpretable boundaries. It leverages all available visits from the Parkinson's Progression Markers Initiative (PPMI) and integrates routinely collected subjective questionnaires and objective clinician-assessed measures. Disease severity is defined using Hoehn and Yahr staging and grouped into three clinically meaningful categories: Healthy, Mild PD (stages 1-2), and Moderate-to-Severe PD (stages 3-5). Three binary classification problems and a three-class severity task were evaluated using stratified cross-validation with imbalance-aware training. To enhance interpretability, SHAP was used to provide global explanations and local patient-level waterfall explanations. Across all tasks, XGBoost achieved the strongest and most stable performance, with accuracies of 95.48% (Healthy vs. Mild), 99.44% (Healthy vs. Moderate-to-Severe), and 96.78% (Mild vs. Moderate-to-Severe), and 94.14% accuracy with 0.8775 Macro-F1 for three-class severity classification. Explainability results highlight a shift from early motor features to progression-related axial and balance impairments. These findings show that multimodal clinical assessments within the PPMI cohort can support accurate and interpretable visit-level PD severity stratification.

Md Mezbahul Islam, John Michael Templeton, Christian Poellabauer +1

School of Computing & Information Sciences, Florida International University, Miami, FL, USA · College of AI, Cybersecurity and Computing, University of South Florida, Tampa, FL, USA

Multimodal Classification Clinical Prediction Parkinson's Disease

Apr 18, 2026cs.CV

Multimodal Fusion of Histopathology Images and Electronic Health Records for Early Breast Cancer Diagnosis

Breast cancer is a leading cause of cancer-related mortality worldwide, and timely accurate diagnosis is critical to improving survival outcomes. While convolutional neural networks (CNNs) have demonstrated strong performance on histopathology image classification, and machine learning models on structured electronic health records (EHR) have shown utility for clinical risk stratification, most existing work treats these modalities in isolation. This paper presents a systematic multimodal framework that integrates patch-level histopathology features from the BreCaHAD dataset with structured clinical data from MIMIC-IV. We train and evaluate unimodal image models (a simple CNN baseline and ResNet-18 with transfer learning), unimodal tabular models (XGBoost and a multilayer perceptron), and an intermediate-fusion model that concatenates latent representations from both modalities. ResNet-18 achieves near-perfect accuracy (1.000) and AUC (1.000) on three-class patch-level classification, while XGBoost achieves 98% accuracy on the EHR prediction task. The intermediate fusion model yields a macro-average AUC of 0.997, outperforming all unimodal baselines and delivering the largest improvements on the diagnostically critical but class-imbalanced mitosis category (AUC 0.994). Grad-CAM and SHAP interpretability analyses validate that model decisions align with established pathological and clinical criteria. Our results demonstrate that multimodal integration delivers meaningful improvements in both predictive performance and clinical transparency.

Aditya Shribhagwan Khandelwal, Mohammad Samar Ansari, Asra Aslam

University of Sheffield, UK · University of Chester, UK

Breast Cancer Computational Pathology Multimodal Classification Oncology Histopathology Image Classification Multimodal Fusion

Apr 18, 2026cs.CV

IMA-MoE: An Interpretable Modality-Aware Mixture-of-Experts Framework for Characterizing the Neurobiological Signatures of Binge Eating Disorder

Binge eating disorder (BED) is the most prevalent eating disorder. However, current diagnostic frameworks remain largely grounded in symptom-based criteria rather than underlying biological mechanisms, thereby limiting early detection and the development of biologically-informed interventions. Emerging studies have begun to investigate the neurobiological signatures of BED, yet their findings are often difficult to generalize due to the reliance on hypothesis-driven parametric models, single-modality analyses, and limited data diversity. Therefore, there is a critical need for advanced data-driven frameworks capable of modeling multimodal data to uncover generalizable and biologically meaningful signatures of BED. In this study, we propose the Interpretable Modality-Aware Mixture-of-Experts (IMA-MoE), a novel architecture designed to integrate heterogeneous neuroimaging, behavioral, hormonal, and demographic measures within a unified predictive framework. By encoding each measure as a distinct token, IMA-MoE enables flexible modeling of cross-modal dependencies while preserving modality-specific characteristics. We further introduce a token-importance mechanism to enhance interpretability by quantifying the contribution of each measure to model predictions. Evaluated on the large-scale Adolescent Brain Cognitive Development (ABCD) dataset, IMA-MoE demonstrates superior performance in differentiating BED from healthy controls compared with baseline methods, while revealing sex-specific predictive patterns, with hormonal measures contributing more prominently to prediction in females. Collectively, these findings highlight the promise of interpretable, data-driven multimodal modeling in advancing biologically-informed characterization of BED and facilitating more precise and personalized interventions in neuropsychiatric disorders.

Lin Zhao, Qiaohui Gao, Elizabeth Martin +5

Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, 07102, NJ, USA · College of Engineering, Northeastern University, Boston, 02115, MA, USA · Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, 30602, NY, 10029 +1

Multimodal Classification Mixture-of-Experts Models Multimodal Learning