Muscle Anatomy

The muscles that power insect flight fall into one of two categories: 1) synchronous muscles that contract under direct control from the nervous system, and 2) asynchronous muscles which have an intrinsic stretch activation response that spontaneously generates wingbeats without the need for signaling from the brain. It is thought that the emergent nature of asynchronous wingbeats provides both adaptive and responsive capabilities for flight control. To date, most flying robots use synchronous actuation. In this paper we develop the first flight-capable flapping wing robot that uses asynchronous actuation. We demonstrate that asynchronous actuation allows wings to respond to changes in the resonant mechanics of the body without control input, and wings can react instantaneously to collisions with obstacles with no extrinsic sensing needed. Flight tests within cluttered environments demonstrate that asynchronous actuation significantly improves stability and performance when compared to synchronous actuation. In total this work demonstrates that a flapping wing robot actuation strategy that emulates the asynchronous muscles of flying insects can provide fast, reactive actuation responses before a control system would need to intervene. This partitioning of embodied control to both the low-level actuation dynamics and and high-level sensorimotor system provides a compelling blueprint for new flying robots.

Factory work is a promising early scenario for embodied AI: assigning repetitive manual jobs to robots has clear economic payoff, and a structured station keeps the jobs tractable for current policies. Vision-Language-Action (VLA) models now dominate as the policy paradigm for these robots. The inference latency of VLA models directly affects robot responsiveness and motion smoothness. However, existing VLA inference frameworks do not fully exploit the characteristics of embodied workloads or account for the distinct bottlenecks across different stages of VLA inference. In this paper, we first characterize embodied workloads and identify substantial task similarity across repeated robot executions. We further find that such similarity extends beyond observations and action trajectories to internal model states. Drawing on these observations, we present rMuscle, a real-time VLA inference framework inspired by human muscle memory. It exploits cross-execution similarity through a dual-phase muscle-memory cache. The Context Cache reuses visual-token outputs to reduce computation, while the Action Cache reuses neuron activation patterns to reduce weight accesses. We keep both the cache memory footprint and access overhead low through online cache recomputation, sliding-window cache retrieval, and mask sharing across consecutive denoising steps. rMuscle achieves 1.29-1.42X speedup on RTX 4090 and Jetson Thor across LIBERO, RoboTwin, and physical manipulation tasks, while maintaining the original success rates on real-world robots.

How do elephant trunks generate complex postures without relying solely on fine segmental activation? We propose that part of this complexity arises from a low-dimensional geometric shortcut: dual-helicity coupling between opposite-handed oblique muscles. In a simplified soft-robotic prototype, varying only two geometric parameters generates a broad library of elephant-like postures, suggesting a dual-layer control architecture with implications for continuum robot design and biological hypotheses.

Robotic bioprinting and Direct Ink Writing (DIW) are being explored towards the treatment of Volumetric Muscle Loss (VML). While previous studies have shown the importance of proper parameter selection on the print outcome, existing approaches often rely on time- and material-intensive design of experiments methods, or require large, well-curated datasets for training machine learning models. In this paper, we propose a physics-based closed-loop robotic bioprinting system capable of near real-time parameter adaptation. The system integrates a 3D point cloud camera and fully autonomous vision-based algorithms to provide quantitative evaluation of printed constructs. This evaluation is fed into a controller that adjusts printing parameters to achieve a desired bead thickness. To assess the framework's performance, four experimental configurations were tested, each repeated three times. In these tests, printing began from an arbitrary initial parameter value, and the controller was tasked with adjusting the parameters to reach the desired thickness. The system converged in all trials, achieving a tracking error below 0.5 mm within an average of 5.2 seconds from the start of printing. The low standard deviation of the converged pressure over different tests (0.04 bar on average) demonstrates robustness and repeatability. Additional experiments were conducted with the controller turned off, enabling direct comparison with open-loop DIW bioprinting, further confirming the effectiveness of the proposed closed-loop framework in achieving the desired bead geometry.

Memory for LLM agents has converged on a single architectural pattern: store experience as text, embeddings, reflections, or rules; retrieve at inference time; let a general-purpose orchestrator interpret what to do. This paper argues that the pattern is the wrong default for personalization. We position Muscle Memory - the practice of compiling recurring user intent into purpose-built specialist agents - as a distinct memory paradigm from retrieval, and we argue that compilation is a better fit for the workloads where current assistants impose a multi-turn tax on their users: making them repeatedly correct format, depth, and scope to obtain a domain-appropriate answer. We support the position with a reference implementation and empirical evidence. The implementation is a four-phase pipeline (Harvest $\rightarrow$ Analyze $\rightarrow$ Augment $\rightarrow$ Evaluate) that mines conversational history, separates behavioral from task patterns, and emits quality-gated executable compiled specialists with two-stage trigger matching. On 90 held-out scenarios across five user personas, the augmented assistant wins 32 of 36 cases where a specialist fires, an 88.9% win rate, with a +2.05 personalization gain and only a $-0.28$ accuracy cost on a 1-4 scale. We discuss why compilation is better suited than retrieval in this regime, what the result implies for the broader memory design space, and what open problems remain.

Fine-grained facial expression recognition (FER) hinges on capturing subtle muscular cues that distinguish adjacent emotions. Yet capturing these cues presents a dilemma. Detector-based methods depend on fragile landmark pipelines, whereas we find that directly transferring foundation models such as DINOv3 under conventional global readouts can cause local evidence dilution: early global aggregation washes out sparse muscular signals and leaves persistent confusion between categories such as fear/surprise and sad/neutral. To recover this evidence, we propose SRE-FER, a readout-level regional residual evidence learning framework. Its core module, RERA, adds zero-initialized residual logits that refine class boundaries while preserving the backbone's global prediction. Training-time action unit (AU) guidance steers regional features toward expression-relevant areas using Facial Action Coding System (FACS)-based anatomical priors, without requiring an external facial pipeline at inference. An optional Full setting further routes sample-specific non-redundant tokens. On three benchmarks, SRE-FER attains 92.76% on RAF-DB, 91.32% on FERPlus, and 67.78% on AffectNet-7, demonstrating highly competitive performance compared to existing FER methods.

Engineered Skeletal Muscle Tissues (ESMs) have become a key structure for biomedical disease modeling and pharmacological screening, yet their functional characterization often relies on simplistic metrics like peak force, discarding critical kinetic information. This is partially due to the high level of mathematical complexity which mechanistic models introduce to capture these dynamics. Hence, exactly the complexity prevents scalable application and widespread adaptation in the field. Here we present a Physics-Flavored Neural Network (PFNN) that automates the kinetic phenotyping of ESMs. Our architecture integrates a stretched-exponential physical model into a CNN-Transformer, enabling the extraction of physically meaningful parameters directly from force-time profiles. To address the scarcity of labeled biological data, we employ a hybrid training paradigm: the model develops a "physical intuition" on synthetic data before undergoing unsupervised self-alignment on unlabeled real-world measurements. Our results demonstrate that this physics-flavored approach achieves high-fidelity parameterization across diverse contractile phenotypes and cell lines, including Duchenne Muscular Dystrophy models. Our scalable, self-improving pipeline bridges the gap between idealized biophysics and noisy \emph{in vitro} data, providing a robust tool for high-throughput biophysical research.

Musculoskeletal robots require an internal body schema that remains consistent under a wide range of physical state changes, including abnormalities such as muscle rupture and actuator jamming. Conventional approaches based on autoencoders or variational autoencoders learn average behaviors by projecting sensor and actuator signals into a low-dimensional latent space; however, exploration within the latent space alone has limited capability to handle out-of-distribution or abnormal states that are not included in the training data. To address this limitation, this study proposes a diffusion-based framework for body schema learning in musculoskeletal robots. Unlike generative models that operate through low-dimensional latent spaces, diffusion models can directly and iteratively estimate physically consistent sensor and actuator values in the high-dimensional space through a denoising process, even under partial observations and constraints, without requiring retraining. By formulating body schema adaptation as a gradient-guided denoising process, the proposed method enables adaptive estimation of appropriate muscle lengths and muscle tensions even under abnormal conditions such as muscle rupture and actuator jamming. The validity of the proposed framework is verified through simulation experiments using a musculoskeletal robot model.

FastSAC-style methods significantly reduce humanoid motion training time but often suffer from notable performance degradation compared with PPO in whole-body tracking tasks. We target this speed-performance gap by introducing LooperMuscle, a composed expert policy learning framework that restores tracking quality while preserving high training efficiency. LooperMuscle combines a semantically structured mixture-of-experts actor, an expert-aware distributional critic, and contribution-routed replay with deferred curriculum scheduling. These three components form a closed training loop in which expert contributions guide data routing, routed data shape value learning, and value gradients in turn refine expert specialization. Empirically, our approach substantially outperforms vanilla FastSAC in motion tracking accuracy while requiring far less wall-clock time than PPO: where FastSAC trains in about 15 minutes but underperforms, and PPO achieves stronger results but requires about 6 hours, LooperMuscle recovers a substantial fraction of the remaining gap to PPO in roughly 45 minutes of simulation training, delivering practical efficiency for rapid policy iteration. The code will be released to benefit the research community at https://loopermuscle.github.io/.

Wound rotor synchronous motors have emerged as a strong alternative that eliminates dependence on REEs. However, WRSM design requires the simultaneous optimization of numerous geometric and electromagnetic parameters, and the high computational cost of conventional finite element analysis severely limits the rapid exploration of the large parameter space. Although there are machine-learning-based surrogate modeling studies in the literature, they generally compare only a limited number of models, exclude deep learning architectures, and do not provide a comprehensive benchmark specific to WRSM. In this study, the performance of a total of eight machine learning and deep learning models from four different algorithmic families was systematically compared for the prediction of WRSM torque and motor efficiency. On a dataset of 3351 samples generated using Latin Hypercube Sampling in the Motor-CAD simulation environment, each model was trained with 10 different random seed values and tuned via Optuna hyperparameter optimization. Different from the existing literature, this study jointly offers a broad model spectrum including recent deep learning architectures such as FT Transformer, a multi-seed reproducibility protocol, and a Pareto analysis of the computational cost-accuracy trade-off. The results revealed that neural-network-based models systematically outperform tree-based models. The FT-Transformer model achieved the highest single-model accuracy with R^2 = 0.9928, producing predictions in 0.33 milliseconds and thus obtaining several orders of magnitude speedup compared to FEA. Model performances were evaluated in a multidimensional manner using R^2, MAE, RMSE, and MAPE metrics.

With the growing demand for realistic virtual humans, parametric body models have become a cornerstone of modern medicine, sports, and entertainment applications. However, most of these models are inherently limited: they only capture the 3D surface of the skin, offering no insight into the complex bio-mechanical structures that generate motion. As more applications expand towards biomechanics, the need for virtual human models that go beyond the skin has become increasingly evident. Traditional soft-tissue simulations, such as FEM, are accurate but non-scalable and too computationally expensive for most common applications. Alternatively, existing biomechanical tools can simulate muscular forces and activations, but do not model changes in external shape, restricting how activations correlate with actual observable anatomy. This motivates a novel inverse research problem: recovering muscle deformations directly from visible surface observations - i.e., from the skin, and thus the pose. In this work, we present SOMA (from Surface Observations to Muscle Anatomy), a person-specific model that infers spatio-temporal muscle behavior from surface signals obtained using RGB cameras, and SKIM, a subject-specific soft-tissue deformation dataset. To the best of our knowledge, this is the first method that attempts to recover muscle deformations from multi-view RGB data. We show how our method provides anatomically grounded animations without the complexity of traditional simulations, leading to a scalable and cost-effective solution. Data and code are available.

This paper investigates multi-degrees of freedom (DoF) joint kinematics estimation under partially observed surface electromyography (sEMG), where only a subset of task-relevant muscles can be measured due to anatomical inaccessibility or sensor constraints. A novel musculoskeletal neural network (MSK-NN) is proposed to estimate multi-DoF joint angles while simultaneously inferring activations for both measured and unmeasured muscles. MSK-NN consists of a CNN-based muscle activation estimator and an embedded MSK forward dynamics module, forming a fully differentiable architecture. Unlike existing hybrid neural frameworks that require additional biomechanical labels (e.g., muscle-tendon forces, joint torques), MSK-NN is trained without direct supervision of internal biomechanical variables. A composite physics-physiology loss is designed by incorporating a joint kinematics loss, a data-driven muscle synergy loss, and an anatomy-guided trend loss. The proposed method is evaluated on two-DoF wrist kinematics estimation across three rhythmic motions with unconstrained speed and amplitude, and one random motion. Compared with CNN, Bi-LSTM, CNN-LSTM, and PET baselines, MSK-NN achieves lower normalized root mean square error (NRMSE) and higher coefficient of determination (R2), especially for the random motion. More importantly, the optimized MSK parameters remain within physiological limits, and the estimated activation of an input-excluded muscle exhibits strong temporal agreement with its recorded sEMG envelope, demonstrating the capability of musculoskeletal (MSK)-NN to recover physiologically plausible activations.

Estimating hip muscle forces and joint moments during gait typically relies on musculoskeletal simulation, which is informative but time-consuming and difficult to apply in clinical settings. This study developed a deep learning framework to predict these hip dynamics parameters directly from lower-limb gait kinematics and compared three representative sequence models under a unified protocol. Gait data were collected from 60 healthy adults under three metronome-guided cadence conditions. Ten bilateral lower-limb joint angles were used as inputs, and OpenSim-derived hip muscle forces and hip joint moments were used as reference outputs. Three deep learning models of LSTM, Transformer, and Mamba were trained and evaluated using the same subject-level split, preprocessing pipeline, and metrics. The best model was then directly tested on an external cohort of 9 patients with osteonecrosis of the femoral head (ONFH) without retraining. In the healthy-subject benchmark, Transformer achieved the best subject-level mean performance for both hip muscle force prediction (RMSE = 1.33 N/kg, MAE = 0.57 N/kg, R2 = 0.819) and hip joint moment prediction (RMSE = 0.11 Nm/kg, MAE = 0.07 Nm/kg, R2 = 0.862), with similar advantages across walking cadences. In zero-shot external validation, Transformer retained moderate predictive ability in ONFH for hip muscle force prediction (RMSE = 1.51 N/kg, MAE = 0.70 N/kg, R2 = 0.537) and hip joint moment prediction (RMSE = 0.17 Nm/kg, MAE = 0.12 Nm/kg, R2 = 0.569). These findings support the feasibility of estimating hip dynamics from gait kinematics, identify Transformer as a strong baseline, and highlight the need for broader pathological validation and improved generalization before clinical application.

Contactless diagnosis of musculoskeletal disorders can potentially improve population health as well as robot behaviours in collaborative settings. However, current diagnosis methods require an in-person physical examination in which a trained physician senses, through contact, the force applied by various muscles. Simulation tools exist, but their use for diagnosis with real data is under-explored. In this paper, we propose an algorithm for identifying which upper-limb muscle group is fatigued. Our algorithm compares the realworld free-space motion of the subject with that of a simulated musculoskeletal model, and is therefore contactless: preventing the need for invasive sensing or in-person assessment. Our algorithm simulates various fatigue conditions using a physics-based musculoskeletal model and extracts diagnostic motion features from both real and simulated data, which are compared for diagnosis. Experimental results on real data demonstrate that the proposed method can reliably distinguish between multiple muscle-groups of fatigue. Additionally, through comprehensive performance comparisons, we show how recent advanced musculoskeletal simulators can be properly configured to address the sim-to-real gap in the context of the fatigue diagnosis task. Our approach can potentially spur further research in remote and automated diagnosis, significantly lowering the barrier to large-scale and early detection.

Surface electromyography provides a practical way to infer human movement intention from wearable muscle recordings, but models trained under a single acquisition setting often lose reliability when the user, session, electrode layout, or gesture protocol changes. This paper proposes AEMG, a self-supervised learning approach designed to extract reusable neuromuscular representations from diverse EMG sources. Eight public gesture datasets are first transformed into a shared signal format to reduce discrepancies in channel configuration, sensor topology, and recording protocol. Instead of relying on fixed-length sliding windows, AEMG identifies contraction events from energy variations and represents them as compact neuromuscular tokens, while ordered token groups describe the coordinated activity of multiple muscles during motion. A spatially and temporally conditioned Transformer is then used to encode these token sequences, preserving information about electrode position, activation timing, and sequential structure. For pre-training, the model constructs a discrete library of contraction prototypes through vector-quantized reconstruction and further learns contextual dependencies by recovering masked neuromuscular tokens from surrounding observations. Experiments under leave-one-subject-out and low-label adaptation settings show that the learned representation improves robustness to unseen users and reduces the amount of calibration data required for gesture recognition. These findings suggest that event-level token modeling offers a scalable route toward adaptable and data-efficient EMG-based motor-intent understanding.

Reliable estimation of neuromuscular activation is a key enabler for adaptive and personalized control in wearable robotics. However, surface electromyography (EMG) remains difficult to deploy robustly outside laboratory settings due to electrode sensitivity, signal non-stationarity, and strong subject dependence. In this work, we propose an adaptive IMU-to-EMG learning framework that reconstructs continuous muscle activation envelopes from wearable inertial measurements across heterogeneous movement conditions. The approach combines a Transformer encoder with Gaussian Error Gated Linear Units (GEGLU-Transformer) to enhance cross-subject generalization and enable rapid subject-specific personalization. Under a strict leave-one-subject-out (LOSO) protocol on a multi-condition lower-limb biomechanics dataset, the proposed architecture achieves r = 0.706 +/- 0.139 and R^2 = 0.474 +/- 0.208 without subject-specific adaptation. With only 0.5% adaptation data, performance increases to r = 0.761 +/- 0.030 and R^2 = 0.559 +/- 0.047, demonstrating rapid adaptation and early performance saturation. These results support attention-based architectures combined with lightweight adaptation as a practical and scalable alternative to direct EMG sensing for real-world wearable robotic applications.

We present a data-driven approach for physics-based, muscle-driven dexterous control that enables musculoskeletal hands to perform precise piano playing for novel pieces of music outside the reference dataset. Our approach combines high-frequency muscle-level control with low-frequency latent-space coordination in a hierarchical architecture. At the low level, general single-hand policies are trained via reinforcement learning to generate dynamic muscle-tendon activations while tracking trajectories from a large reference motion dataset. The resulting tracking policies are then distilled into variational autoencoder (VAE) models, yielding smooth and structured latent spaces that abstract away low-level muscle dynamics. For the high level, we train piece-specific policies to operate in this latent space, coordinating bimanual motions based on specific goals, denoted by note events extracted from given musical scores, to synthesize performances beyond the reference data. In addition, we present an enhanced musculoskeletal hand model that supports fine control of fingers for accurate low-level motion tracking and diverse high-level motion synthesis. We evaluate the control pipeline of our approach on a diverse piano repertoire spanning multiple musical styles and technical demands. Results demonstrate that our approach can synthesize coordinated bimanual motions with accurate key presses, and achieve the state-of-the-art performance of piano playing in physics-based dexterous control. We also show that our musculoskeletal hand model demonstrates superior biomechanical stability and tracking precision compared to the existing model, and validate that our musculoskeletal hand model and muscle-driven controller can generate physiologically plausible activation patterns that align with human electromyography (EMG) recordings.