Neuroflex

This paper introduces NeuroSymbEAD, a large-scale neuro-symbolic caption dataset featuring an ego-centric knowledge graph (KG) of static and dynamic objects annotated with classes, categories, heading directions, orientations, and distances from the ego-vehicle. These annotations are used on the KITTI-360 dataset to generate multilevel textual captions representing a lightweight version of an ego-centric scene map. Outdoor scene-map reconstruction, visual recognition, and object grounding establish baselines for driving common sense and traffic/scene understanding. For these purposes, natural language-based grounded captioning of objects and their complex relationships is a widely adopted contextual representation for indoor scene tasks. Neuro-symbolic representations have proven effective in handling structured information for various computer vision and language applications. Our data annotation pipeline allows the generation of varied map segments, populating simulated or real objects within the bounding boxes predicted by any 3D object detection network, and building hierarchical text captions. We benchmark our neuro-symbolic and ontological caption generation using pre-trained grounding and learned auto-regressive captioning networks. By converting 3D driving scenes into structured ego-centric language, NeuroSymbEAD provides a benchmark for vision-language and foundation models for traffic-scene explanation, 3D reasoning, and interpretable autonomous-driving perception.

Pediatric brain tumors are a leading cause of cancer-related mortality in children, and their small, rare, and often low-contrast subregions make accurate manual delineation challenging. Reliable automated segmentation is therefore needed to support diagnosis, treatment planning, and response assessment. Accordingly, we introduce NeuroTS-Net, a three-dimensional encoder-decoder convolutional neural network architecture for multi-class semantic segmentation that incorporates a dual-scale raw-detail stream, adaptive low-resolution context selection, and detail-preserving multipath downsampling. These components preserve fine intensity and boundary information while efficiently modeling broader tumor context. NeuroTS-Net was trained on the BraTS 2026 pediatric dataset without external data or pretrained weights and evaluated against nnU-Net and MedNeXt under the same experimental protocol. NeuroTS-Net outperformed the baseline methods, achieving whole-tumor and tumor-core Dice scores of 0.938 and 0.937 on the internal validation set and 0.927 and 0.926 on the official challenge validation set. The code is open-sourced at: https://github.com/maenstru56/NeuroTS.

Video compression aims to minimize reconstruction distor tion under a constrained bit rate. Existing video implicit neural representations (INRs) often decode frames independently, leaving intermediate features unconditioned on previous reconstructions and content embeddings without explicit temporal prediction. We propose TCNeRV, which exploits reconstructed context in both feature and embedding domains. Its multi-scale temporal-context fusion (MTCF) module injects gated historical features at multiple decoder scales, while temporal embedding-residual coding (TERC) predicts each content embedding and codes only its residual. With approximately 3M parameters, TCNeRV achieves an average PSNR of 36.08 dB on the UVG dataset, outperforming HNeRV-Boost by 2.20 dB. It reduces BD-rate by 22.06%, 66.73%, and 29.85% relative to HM, DCVC, and HiNeRV, respectively, demonstrating competitive rate-distortion performance with limited model capacity.

Sparse DNN accelerators specialize in ANN or SNN execution, leaving energy or latency on the table when workload characteristics vary within a layer. Hybrid accelerator designs that switch modes at layer or tile granularity suffer from low PE utilization since one core type idles whenever the other is active. NeuroFlex is the first accelerator to assign every output element independently to ANN or SNN execution mode with zero accuracy loss. We extend integer-exact ANN-SNN equivalence from layers to individual output elements, thereby enabling mode switching with no conversion error. An offline cost-guided scheduler scores each element by its marginal energy-delay trade-off and packs work across PEs, achieving 97-99% PE utilization compared to 40-45% for layer-wise hybrids. NeuroFlex reduces EDP by 57-67% over a strong ANN-only baseline and delivers up to 2.5x speedup over a dual-sparse SNN-only baseline. Our cost-guided scheduler improves throughput by 16-19% over random element assignment across vision, language, and transformer workloads.

Wearable EEG systems may expose sensitive information beyond their intended health function, creating substantial risks to neuroprivacy. In this work, we show that commonly used EEG features can reveal participant identity and demographic attributes in addition to supporting the intended cognitive task. Wearable EEG is increasingly being explored for cognitive monitoring, neurological assessment, and longitudinal digital-health applications, yet many systems assume that transmitting compact spectral or spatial features instead of raw EEG provides sufficient privacy protection. Using EEGMAT as a motivating case study, we find that compact EEG features achieve a balanced accuracy of 0.788 for cognitive-state classification while enabling gender, age, and subject-identity inference with balanced accuracies of 0.858, 0.789, and 0.692, respectively. We further show that privacy-aware representation learning preserves task performance at 0.781 while reducing these inference accuracies to 0.563, 0.467, and 0.206. These findings motivate purpose-limited representations and explicit privacy auditing in wearable neurohealth systems.

Spiking neural networks (SNNs) offer a promising pathway to energy-efficient AI and brain-inspired computing. However, their widespread adoption is hindered by a lack of fast, accessible, and versatile simulation frameworks. In this paper, we introduce SuperNeuroMAT, an open-source, scalable, and highly efficient Python-based SNN simulator. We devise a novel matrix-based approach to model the leaky integrate-and-fire (LIF) neuron dynamics and natively support dense and sparse execution modes. This enables fast simulation of approximately 10,000 neurons in dense mode and 100,000 neurons in sparse mode on standard laptops and desktops without requiring specialized hardware. We demonstrate that SuperNeuroMAT consistently outperforms four established SNN simulators---NEST, Brian2, BindsNET, and snnTorch---on two performance metrics (execution speed and peak resident memory) and across various network sizes and connection probabilities. Furthermore, we demonstrate SuperNeuroMAT's applicability across a diverse set of problems. SuperNeuroMAT can efficiently handle conventional machine learning benchmarks such as the Digits and citation network datasets as well as neuromorphic event-based vision tasks such as N-CARS and ASL-DVS. Moreover, it can be extended beyond machine learning workloads and facilitate general-purpose workloads. We validated this by implementing the neuromorphic shortest path algorithm and two arithmetic primitives (addition and multiplication). SuperNeuroMAT can be installed via the Python Package Index (PyPI), thereby lowering the barrier to entry into the field of neuromorphic computing and accelerating the broader development of neuromorphic algorithms.

Long-tailed class-incremental learning (LT-CIL) must learn new classes from imbalanced streams while retaining old classes. Existing methods mainly change replay, classifiers, or losses. We study a different factor, namely how strongly the feature representation should be updated at each task boundary. We propose NeuroGuard, an update-control method added to DGR, a replay-based LT-CIL baseline, without adding learnable parameters. NeuroGuard preserves DGR's replay memory, classifier, and set of loss terms. Adaptive Gradient Scaling (AGS) converts teacher uncertainty into one task-wise gradient scale. Confidence-Ranked Knowledge Distillation Reweighting (CRK) gives larger knowledge-distillation weights to replay samples that the teacher predicts less decisively. Fragility-Blended Entropy Gate (FBE) adds old-memory leakage to the scale decision. Across five LT-CIL settings, NeuroGuard improves over DGR in every setting. In the four main benchmark comparisons, it achieves the best task-agnostic accuracy among the compared methods. The gains extend to both old- and new-class accuracy, while medium-frequency accuracy improves consistently across all five settings. Controlled comparisons show that the gain does not come from generic gradient suppression: AGS outperforms a matched fixed-scale control in all five settings, demonstrating that boundary-specific scaling is more effective than applying the same average scale throughout learning.

Headache is the most common neurological disorder in children and substantially affects quality of life. We investigated whether resting-state functional MRI (rs-fMRI) can support pediatric headache classification using machine learning. We encoded rs-fMRI data using NeuroSTORM, a recent foundation model, and fine-tuned it to distinguish healthy controls from children with headache and subsequently classify headache subtypes. We compared NeuroSTORM with a standard neuroscience approach using functional-connectivity (FC) matrices derived from brain activity as predictors. Using 189 rs-fMRI scans from 110 individuals collected across two visits (prevalence of any headache: 74%), NeuroSTORM achieved an area under the receiver operating characteristic curve (AUROC) of 0.82 (95% CI, 0.82-0.82) and an area under the precision-recall curve (AUPRC) of 0.93 (95% CI, 0.93-0.94) for discriminating headache from non-headache. In contrast, models trained on FC matrices showed lower performance (AUROC, 0.67 [95% CI, 0.67-0.67]; AUPRC, 0.85 [95% CI, 0.85-0.85]). In multiclass classification of healthy controls, chronic migraine, and non-chronic headaches (e.g., post-viral headache, new daily persistent headache, post-traumatic headache), NeuroSTORM achieved a macro-AUROC of 0.69 (95% CI, 0.68-0.69). Results suggest that the approach can distinguish chronic migraine but has difficulty differentiating other headache subtypes from chronic migraine. Overall, under limited-data conditions, NeuroSTORM appears to capture latent rs-fMRI representations that transfer to headache-related tasks without relying on FC features. These findings provide proof of concept for fMRI-based prediction of pediatric headache and highlight potential future utility for subtype identification and individualized treatment strategies.

Decoding continuous motor trajectories from neural activity is essential for developing practical brain-computer interfaces (BCIs). However, current neural decoders are constrained by the limited scale and heterogeneity of neural recordings. In contrast, behavioral data can be collected more readily and at substantially larger scale from humans, animals, simulations, and robotic systems. Here, we introduce NeuroPB, a framework that scales neural decoding by transferring knowledge from pretrained behavioral representations. NeuroPB first pretrains a motor encoder on large-scale motor behavior data and then aligns neural activity with the resulting behavioral representation space using a limited set of paired neural-behavioral recordings. A neural encoder and lightweight motor decoder are subsequently optimized to reconstruct continuous movement from the aligned neural representations. Across multiple macaque motor datasets, behavioral pretraining improves trajectory decoding, including an 11% $R^2$ increase on center-out and 8% on random-target compared with training the motor encoder from scratch. Notably, pretraining on robotic trajectories achieves performance comparable to pretraining on macaque trajectories, demonstrating that transferable kinematic structure is shared across biological and artificial models. Moreover, decoding performance improves as the scale and diversity of robotic pretraining data increase, when the amount of neural data is fixed. Pretraining also enhances generalization across recording sessions, subjects, and motor tasks, with only 10% calibration needed to match training from scratch. Overall, these results establish behavioral pretraining as a scalable source for neural decoding and provide a promising route toward high-performance and calibration-efficient BCIs under limited neural data.

Multimodal medical large language models remain structurally weak for neuro-oncology because volumetric evidence is compressed into generic visual tokens and diagnostic conclusions often lack an auditable link to MRI regions. We present NeuroMosaic, a 3D multimodal language model that converts multi-sequence brain MRI into anatomy-indexed regional tokens, aligns them with clinical narrative and molecular concepts, and generates evidence-linked outputs. The architecture combines a multi-resolution volumetric tokenizer, a neuroanatomical graph router, a molecular concept memory, and selective risk control. Across four glioma cohorts, NeuroMosaic achieved an internal subtype macro-F1 of 0.827 and external macro-F1 values of 0.784, 0.761, and 0.742. On UPenn-GBM, it improved over the strongest matched-input baseline by 3.6 percentage points (95% CI: 1.8 to 5.4, adjusted p = 0.0018), with IDH, 1p/19q, and MGMT AUROCs of 0.918, 0.861, and 0.781. Evidence pointing accuracy reached 0.703, and targeted evidence deletion reduced correct-answer probability by 0.187, compared with 0.046 for random deletion. These results establish anatomy-indexed routing as a measurable mechanism for accurate, grounded, and calibrated volumetric medical-language reasoning.

In real-world machine learning applications, incomplete observations create a fundamental challenge. Researchers have come up with several ideas to address this crucial problem. However, current models still face challenges in balancing scalability and structural consistency. This study proposes a feature imputation method, called FILLER, that deliberately searches the two-dimensional latent space produced by a generative model and fills the missing values with appropriate entries. The generative model is trained on fully observed data to generate samples from the latent space, and FILLER uses this trained model to impute the values missing in the corrupted test samples. In this study, G-NeuroDAVIS serves the purpose of the generative model. This work also presents a mathematical proof on the convergence of the iterative search. Finally, FILLER has been evaluated on several image datasets under random and structured missingness patterns with varying levels of imputation complexities. In order to justify the efficacy of FILLER, it has been compared against existing state-of-the-art solution strategies in terms of RMSE, PSNR, and SSIM. In addition, Wilcoxon signed-rank test has been carried out to validate statistical significance. Moreover, downstream analyses (classification and clustering) have also established the quality of imputation in terms of standard metrics.

Artificial Intelligence (AI) systems often perform well on isolated tasks but struggle under continual learning conditions, where training on new tasks can overwrite previously acquired knowledge, a failure mode known as catastrophic forgetting. Biological learning systems reduce this interference through complementary memory processes involving rapid hippocampal encoding and slower cortical consolidation. This study introduces NeuroSynth, a brain-inspired continual reinforcement learning architecture designed to mitigate catastrophic forgetting through a dual-pathway consolidation mechanism. NeuroSynth separates rapid task acquisition from long-term retention using distinct "plan" and "habit" pathways combined with replay and knowledge distillation. NeuroSynth was evaluated against Proximal Policy Optimization (PPO) and Elastic Weight Consolidation (EWC) across three sequential navigation tasks with changing goal locations in a non-revisitation continual learning setting. Across six independent seeds, NeuroSynth preserved substantially more early-task knowledge than PPO after sequential training, achieving 18.00% Task A success rate compared to 0.33% for PPO (p = 0.014929, Cohen's d = 1.49) and 35.33% Task B success rate compared to 0.00% for PPO (p = 0.002376, Cohen's d = 2.31). NeuroSynth also demonstrated higher final Task C performance than EWC, achieving 9.00% compared to 2.00% (p = 0.226643, Cohen's d = 0.56), indicating a moderate but not statistically significant advantage. These findings suggest that biologically inspired consolidation mechanisms may improve the stability-plasticity balance in continual reinforcement learning systems.

We study the expressivity of shallow polynomial neural networks (PNNs) with monomial activation functions over finite fields. For a given architecture, we define a neuromanifold as the image of the map from all possible network weights into the product of polynomial rings. We quantify the expressivity by the cardinality of the neuromanifold, and derive a natural lower and upper bound. This leads to counting rational points over finite fields, a problem closely linked to the Weil conjectures. Finally, we present an architecture that exhibits a striking difference in the neuromanifolds when considered over a characteristic zero versus a finite-characteristic field, illustrating the critical role of field characteristic in the notion of expressivity.

Seizure diagnosis from EEG signals is a critical yet persistently challenging task, due to the complicated neural dynamics and the spurious connections in inter-channel modeling. While spatial-temporal graph neural networks (STGNNs) have advanced EEG brain network representation learning, the resulting graph structures suffer from low clinical plausibility and limited interpretability due to their purely data-driven nature. To this end, we introduce NeuroGRIP, a retrieval-augmented graph refinement framework that incorporates external medical knowledge to calibrate noisy EEG graphs. We first construct a large-scale, domain-specific knowledge base derived from authoritative clinical guidelines. Leveraging large language models, we extract structured biomedical entities and relations to form a textual knowledge graph (KG), which serves as external knowledge source of clinical priors. Our framework performs alignment-aware query construction by projecting STGNN-generated EEG node embeddings into the semantic space of KG. Semantic queries are then executed via FAISS-based similarity search over knowledge triplets to retrieve relation evidence. Each predicted edge is assigned a confidence score based on retrieved similarity, relation type, and source reliability, enabling us to prune medically implausible edges from the originally predicted graph. Extensive experiments on TUSZ and CHB-MIT demonstrate that NeuroGRIP not only improves seizure detection accuracy but also enhances interpretability by grounding each prediction in clinically validated knowledge. This work provides the first unified framework that tightly couples brain dynamics with external medical expertise via retrieval-augmented reasoning, paving the way for knowledge-enhanced, explainable clinical diagnosis. The code is available at: https://github.com/LincanLi-X/NeuroGRIP.

In this paper, we propose deep learning based NeuroMem-FHP framework for estimating the parameters of the fractional Hawkes process (FHP), a self-exciting point process that captures long-range dependence through a fractional Mittag-Leffler excitation kernel. Two neural architectures, namely a Long Short-Term Memory (LSTM) network and a Transformer, are developed to estimate the model parameters $(μ,γ,α,β)$ directly from sequences of inter-arrival times without requiring computationally intensive likelihood optimization. Experiments on synthetic data that both neural models significantly outperform the classical Maximum Likelihood Estimation (MLE) method, with the Transformer achieving the highest estimation accuracy (MSE = $0.1634$), followed by the LSTM (MSE = $0.1752$), compared to MLE (MSE = $2.8032$). An ablation study further examines the effects of key hyperparameters on model performance. The proposed framework is also on two real-world high-frequency datasets, namely AAPL NBBO transaction data and Montgomery County 911 emergency call records. Using a predictive validation approach, event sequences simulated from the estimated parameters closely reproduce the empirical distribution, tail behavior, and temporal dependence structure of the observed data. These results demonstrate that Transformer-based parameter estimation provides an accurate and efficient alternative to conventional estimation techniques for FHP and offers a promising framework for modeling event-driven systems with long-memory dynamics.

Neuromorphic visuo-tactile sensing offers a promising paradigm for low-latency and low-power robotic perception. However, existing systems still rely heavily on a host computer for event readout, preprocessing, or relaying prior to chip inference. This paper presents GelNeuro, a fully integrated sensing-computing visuo-tactile system that directly pairs a GelSight Mini-based optical tactile front end with the Speck2f neuromorphic system-on-chip (SoC). Contact-induced marker motions are captured as dynamic vision sensor (DVS) events and routed through the on-chip network to a spiking convolutional neural network (SCNN) classifier. To mitigate accuracy degradation during 8-bit deployment, a hardware-aware weight clamping strategy is introduced. Evaluated on a 15-class natural texture recognition task, hardware-in-the-loop testing on the physical chip achieves a 96.3% accuracy within an 80 ms inference window. Notably, the system consumes only 19.6 mW of board-level active power-over three orders of magnitude lower than conventional CPU/GPU baselines on the same benchmark. GelNeuro also exhibits robust generalization across unseen contact depths, demonstrating the viability of direct sensor-to-chip tactile recognition on edge neuromorphic hardware.

Safe landing-site assessment in unstructured environments remains a key challenge for autonomous UAV deployment, as vision-only learning approaches often degrade under terrain variability and provide limited transparency in safety decisions. We present NEUROSYMLAND, a neuro-symbolic landing-site assessment system that integrates lightweight perception with explicit safety reasoning. The framework constructs a probabilistic semantic scene graph from onboard visual input and evaluates candidate landing regions using symbolic constraints capturing terrain flatness, obstacle clearance, and spatial consistency, enabling structured reasoning under perceptual uncertainty while maintaining edge-feasible execution. Across 72 simulated landing scenarios spanning diverse terrains, NEUROSYMLAND achieves 61 successful assessments, outperforming four competitive baselines (37-57 successes). To evaluate deployability, we further conduct 100 hardware-in-the-loop trials with randomized initial poses, profiling end-to-end latency, stage-wise execution time, and system-level metrics including CPU/GPU utilization, memory footprint, and power consumption. Results demonstrate improved robustness and interpretability with bounded edge-resource usage. Profiling shows that symbolic reasoning contributes only a small fraction of end-to-end latency, while the main computational cost arises from perception and PSSG construction. These results demonstrate the feasibility of deploying the landing-site assessment stack on edge-constrained UAV hardware, and all source code, datasets, prompts, and symbolic rule refinement examples are released in an open-source repository

Monitoring cognitive load during online learning could help instructors identify content that learners find difficult, but remote settings remove the visual cues that support this judgement in a classroom. We study whether a single-channel, consumer-grade EEG device (the NeuroSky MindWave Mobile 2) can distinguish easy from difficult educational-video content, using the publicly available dataset of Wang et al. [24] (ten learners, one excluded for excessive noise, leaving nine). We implement a hybrid CNN+LSTM+Attention model that combines the raw waveform with band-power features. In a within-subject setting, the model reaches up to 78.5% accuracy, compared with 55% for conventional feature-based classifiers; regularization (dropout and L2) closes the large gap between training and validation accuracy that we observe without it, keeping validation accuracy stable at roughly 68-73%. We are deliberately cautious about these numbers: with only nine subjects, within-subject evaluation is optimistic, and we argue that subject-independent evaluation -- in which no learner appears in both training and test data -- should be the standard for this task. To that end we release a reproducible evaluation pipeline. We frame the work as a feasibility study rather than a deployable system, and pair it with an open, notebook-based tool that records EEG, runs inference, and visualizes estimated cognitive load as a heatmap over the video timeline to help educators locate potentially challenging segments.

INTRODUCTION: Accurate MRI-based identification of Alzheimer's disease (AD), mild cognitive impairment (MCI), and related dementias remains challenging because disease-related structural changes are often subtle and heterogeneous. We developed NeuroBridge, a clinically guided multi-task MRI framework for neurodegenerative disease diagnosis. METHODS: NeuroBridge integrates large-scale self-supervised MRI pretraining with hippocampal segmentation, hippocampal atrophy classification, and reconstruction objectives, followed by gated fusion fine-tuning. Performance was evaluated across ADNI and OASIS cohorts, including cross-cohort transfer, probability-based analysis, and opportunistic screening. RESULTS: NeuroBridge achieved the highest performance across evaluated classification tasks, reaching 88.17% accuracy for AD versus cognitively normal controls in ADNI and 82.78% in OASIS. The largest gains occurred in MCI-related and mixed-diagnosis settings. The framework demonstrated strong cross-cohort generalization, systematic associations between predicted-class probability and accuracy, and the feasibility of probability-based opportunistic screening. DISCUSSION: Clinically guided multi-task representation learning improves neurodegenerative MRI diagnosis beyond conventional single-task approaches. NeuroBridge provides a robust and scalable framework for dementia assessment and MRI-based opportunistic screening.

Reconstructing continuous speech from scalp electroencephalography (EEG) remains fundamentally challenging. EEG provides a weak, spatially diffuse, and highly variable measurement of distributed cortical activity, whereas speech is organized as a coherent acoustic trajectory with strong harmonic and temporal structure. The resulting mismatch makes waveform regression unstable and causes stochastic multi-step generation to be sensitive to artifact-dependent conditioning and subject variability. We introduce NeuroSonic, a conditional flow-matching framework for EEG-to-speech reconstruction. Instead of predicting waveforms directly or refining them through stochastic denoising, NeuroSonic learns a deterministic probability-flow velocity field that transports a noise-corrupted acoustic state toward clean speech under EEG conditioning. EEG and audio are embedded into a shared token space and processed by a time-conditioned gated Transformer that parameterizes the transport ordinary differential equation. This formulation models trajectory evolution explicitly while avoiding iterative stochastic sampling. We evaluate NeuroSonic on the CineBrain and EAV benchmarks under cross-subject evaluation. Across both datasets, the proposed method improves distributional realism, spectral fidelity, and perceptual quality over representative GAN-, diffusion-, and mean-flow baselines, with up to a 26.3% gain in overall perceptual quality. The performance gap is most evident in artifact-heavy segments, where conditioning variability is strongest. These findings indicate that deterministic conditional transport provides a stable and effective formulation for EEG-driven speech reconstruction. Code is available at https://github.com/Y-Research-SBU/NeuroSonic/ .

Electroencephalography (EEG) foundation models increasingly rely on multi-dataset training and evaluation, yet public EEG datasets still lack a shared task specification layer that can turn heterogeneous recordings into reusable benchmark units. Existing standards organize files, metadata, and provenance, but they do not specify EEG tasks under a common language and rulebook, leaving critical task semantics scattered across papers, code, and manual interpretation. We investigate whether heterogeneous public EEG datasets can be standardized through a structured task specification language paired with a shared rulebook. Our methodology represents each benchmark entry as a task document synchronized with an executable task kernel, with the rulebook defining task fields, evidence requirements, document-kernel alignment, review states, and machine-checkable constraints. Using this methodology, we release a community-reviewed EEG benchmark corpus centered on 53 completed and reviewed entries with 245 task definitions spanning diverse paradigms, and we introduce NeuroDoc and NeuroAudit as the operational support layer for rulebook-guided drafting, upgrading, review, amendment, and release management. We further examine whether the resulting benchmark units can be instantiated in a shared downstream setting across four EEG foundation model backbones, providing execution-based evidence for reusable, auditable, and executable EEG benchmarking infrastructure.

A central challenge in EEG authentication is that models are typically tied to the acquisition settings in which they are trained. In particular, variations in headset hardware, channel layout, and signal duration create heterogeneous recordings that existing models are not designed to handle, causing each new headset or dataset to be treated as a separate model-development problem. This fragmentation limits multi-dataset learning, hinders knowledge transfer, and reduces model reusability. To address this limitation, we present NeuroShield, a reusable foundation model for EEG authentication that learns identity-discriminative embeddings from variable-channel and variable-length EEG recordings through a dual-stage transformer architecture. We pretrain NeuroShield on three public EEG datasets comprising 15{,}762 subjects and 28{,}116 sessions, and evaluate transfer on two unseen downstream datasets. Our evaluations show that, after fine-tuning, NeuroShield reduces equal error rate by 0.44--8.06 percentage points relative to the state of the art. NeuroShield further generalizes to segments longer than those seen during training and operates across channel layouts not encountered during pretraining. These results establish NeuroShield as a reusable and adaptable EEG identity encoder across heterogeneous recording settings. We release NeuroShield as open source to support reproducibility and community adoption.

Event-based tactile sensing offers low-latency signal acquisition for contact-rich robotic interaction. This paper investigates contact-angle estimation using event streams from an event-based tactile sensor (NeuroTac) and compares three event-derived spatial contour representations: a dynamic representation capturing recent event activity, a static representation recovering a more persistent contact state, and their combined representation. Across the evaluated motion scenarios, all representation pipelines exhibited P99 processing latency below 10 ms at all tested sampling intervals, demonstrating their potential for high-frequency event-based tactile angle estimation in robotic manipulation. The static representation consistently achieved marginally better performance than the dynamic and combined representations under scenario-specific training, yielding a mean overall MAE of 0.160° during continuous sensor rolling and a stop-phase mean MAE of 0.251° during randomly inserted motion interruptions. It also exhibited smaller performance fluctuations across speed and indentation depth variations than the other two representations.

Large language models remain vulnerable to jailbreak attacks that hide harmful intent behind seemingly ordinary requests such as role-play, translation, encoding, adversarial suffixes, and multi-turn buildup. Existing defenses still struggle to handle these attacks without over-blocking benign but sensitive requests, partly because they often apply the same action to every prompt and therefore fail to balance safety and helpfulness. We propose NeuroArmor, a white-box runtime defense that uses prompt-specific safe variants as a local safety reference for deciding when intervention is needed and, once triggered, as safe targets for intervention. For each prompt, NeuroArmor builds K safe variants, compares the prompt state against this local safe reference in hidden-state space, and routes anomalies either to a refusal branch for malicious prompts or to a helpful recovery branch for borderline benign prompts. On Llama-3-8B-Instruct, NeuroArmor reduces malicious attack success rate (ASR) from 41.56% to 1.57% while lowering benign false positive rate (FPR) on the shared benign pool from 30.26% to 22.05%; matched baselines remain substantially weaker on this trade-off. External-judge and manual behavioral evaluations further show that the remaining non-blocked outputs are much less likely to be operationally harmful. Overall, NeuroArmor provides a more effective runtime strategy for jailbreak defense by combining prompt-specific consistency checking, routing, and selective intervention.

High-density electromyography (HD-EMG) has emerged as a powerful modality for decoding fine-grained neuromuscular activity, enabling real-time neural-machine interfaces (NMIs) for applications such as prosthetic control, rehabilitation, and augmented interaction. While deep learning approaches such as convolutional neural networks (CNNs)have demonstrated high classification accuracy for EMG-based gesture recognition, their deployment on embedded hardware remains a major challenge due to computational and memory constraints. This paper presents NeuroEdge, a real-time HD EMG-based NMI system that performs gesture recognition entirely on resource-constrained microcontrollers. The system features two custom-designed modules: the HD-EMG StreamBridge, a wireless communication interface that streams raw HD-EMG data from a Quattrocento amplifier to an ESP32 microcontroller; and the EdgeDL Inference Engine, a lightweight deep learning framework executing on a Sony Spresense microcontroller. A compact 1-dimensional CNN optimized for embedded inference processes, sliding windows of EMG data in real time. Data streaming and inference are pipelined and synchronized through an architecture that utilizes Direct Memory Access (DMA) for data transfer and Serial Peripheral Interface (SPI) burst communication between the ESP32 and Spresense, ensuring low-latency performance. Experimental results show that NeuroEdge achieves a real-time classification accuracy of 90% across seven hand gestures, with a total average latency of 83 ms using 192 channels of HD-EMG recorded from the forearm. Our system demonstrates the feasibility of deploying complex HD-EMG-based gesture recognition on microcontroller-based edge devices, bridging the gap between high-resolution biosignal acquisition and deep learning-based embedded inference for next-generation NMIs.

We present NeuroQA, a large-scale benchmark for visual question answering in 3D brain magnetic resonance imaging (MRI), with 56,953 QA pairs from 12,977 subjects across 12 datasets. It spans ages 5-104 and five clinical domains: Alzheimer's, Parkinson's, tumors, white matter disease, and neurodevelopment. Unlike prior medical Visual Question Answering (VQA) efforts that operate on 2D slices or rely on narrow diagnostic labels, NeuroQA pairs every item with a full 3D volume. It evaluates 11 clinically grounded reasoning skills across Yes/No, multiple-choice, and open-ended formats. Of the 203 templates, 131 are image-grounded (answerable from a 3-plane viewer) and 72 are image-informed (ground truth from quantitative volumetry or clinical instruments). To remove text-only shortcuts, we apply answer-distribution refinement, reducing closed-format text-only accuracy from $>$80% to 44.6%; image necessity is assessed separately through an image-grounding protocol released with the benchmark. A 38-rule deterministic pipeline and two rounds of expert review verify every QA pair against FreeSurfer measurements, metadata, or radiology report fields, with zero same-subject contradictions across templates. We conduct a clinician evaluation in which two clinicians independently assess 100 frozen test items on a three-plane viewer. On closed-format (Yes/No + multiple-choice) test-public items, the best zero-shot vision-language model and a supervised 3D CNN baseline reach 47.5% and 43.7% accuracy respectively, both below the 49.4% text-only majority-template floor. NeuroQA adopts a two-tier release with public QA pairs for open-access datasets and reproducible generation scripts for datasets restricted by data use agreements (DUAs), plus subject-level splits, a held-out private test set, and an online leaderboard.

Multi-agent language systems are often built as hand-designed workflows, where agents are assigned semantic roles and communication protocols are specified in advance. We propose NeuroMAS, a method that first treats a multi-agent language system as a trainable and scalable neural-network-like architecture with LLM agents as nodes and intermediate textual signals as edges. In NeuroMAS, agent nodes are role-free but structure-aware: the topology only determines how information can flow in general, while reinforcement learning training determines how nodes communicate, specialize, and coordinate. This formulation shifts multi-agent design from workflow engineering toward architecture design, where depth, width, connectivity, and growth protocol become scalable sources of capability. Further, we provide a theoretical perspective showing why such modular textual computation is more parameter-efficient when tasks admit hierarchical decompositions. Experiments show that NeuroMAS improves significantly over both inference-time and trained multi-agent baselines. We further find that organizational scaling is path-dependent: larger systems can be challenging to train from scratch, but become feasible when grown progressively from smaller trained systems. These results suggest that learned neural multi-agent systems are a promising scaling axis for LLMs.

Neural ordinary differential equations (Neural ODEs) often fit training trajectories while generalizing poorly to unseen initial conditions and long horizons. We propose MPINeuralODE, which combines a soft physics-informed residual with a Multiple-Initial-Condition (MIC) multiple-shooting curriculum whose ingredients are structurally complementary: the physics term anchors the vector-field magnitude on the support that MIC enlarges. We evaluate along three axes: out-of-sample error, long-horizon stability, and Hamiltonian drift, which together expose whether the learned dynamics recover the underlying vector field. On Lotka-Volterra, MPINeuralODE achieves the lowest out-of-sample and long-horizon MSE among data-driven methods, with a 24% reduction over the baseline Neural ODE, while essentially matching the PINN ablation on Hamiltonian drift.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and a major cause of dementia. Structural MRI is widely used to analyze AD-related brain atrophy; however, most deep learning methods rely on computationally expensive 3D convolutional neural networks (CNNs), limiting deployment in resource-constrained settings. This work introduces two main contributions. First, we propose a pipeline that converts T1-weighted MRI into anatomically informed 2D point clouds using Anatomical Priority Sampling (APS), producing ADNI-2DPC, the first neuroanatomically labeled MRI-derived point cloud dataset. Second, we present NeuroAPS-Net, a lightweight geometric deep learning model that incorporates anatomical priors via region-aware feature encoding and ROI token aggregation. Experiments on ADNI-2DPC demonstrate that NeuroAPS-Net achieves competitive classification accuracy while significantly reducing inference latency and GPU memory compared to state-of-the-art point cloud methods. These results highlight the potential of anatomically guided point cloud learning as an efficient and interpretable alternative to voxel-based CNNs for AD classification.

Visual speaker recognition based on lip motion offers a silent, hands-free, and behavior-driven biometric solution that remains effective even when acoustic cues are unavailable. Compared to traditional methods that rely heavily on appearance-dependent representations, lip motion encodes subject-specific behavioral dynamics driven by consistent articulation patterns and muscle coordination, offering inherent stability across environmental changes. However, capturing these robust, fine-grained dynamics is challenging for conventional frame-based cameras due to motion blur and low dynamic range. To exploit the intrinsic stability of lip motion and address these sensing limitations, we propose NeuroLip, an event-based framework that captures fine-grained lip dynamics under a strict yet practical cross-scene protocol: training is performed under a single controlled condition, while recognition must generalize to unseen viewing and lighting conditions. NeuroLip features a 1) Temporal-aware Voxel Encoding module with adaptive event weighting, 2) Structure-aware Spatial Enhancer that amplifies discriminative behavioral patterns by suppressing noise while preserving vertically structured motion information, and 3) Polarity Consistency Regularization mechanism to retain motion-direction cues encoded in event polarities. To facilitate systematic evaluation, we introduce DVSpeaker, a comprehensive event-based lip-motion dataset comprising 50 subjects recorded under four distinct viewpoint and illumination scenarios. Extensive experiments demonstrate that NeuroLip achieves near-perfect matched-scene accuracy and robust cross-scene generalization, attaining over 71% accuracy on unseen viewpoints and nearly 76% under low-light conditions, outperforming representative existing methods by at least 8.54%. The dataset and code are publicly available at https://github.com/JiuZeongit/NeuroLip.

Sparse DNN accelerators specialize in ANN or SNN execution, leaving energy or latency on the table when workload characteristics vary within a layer. Hybrid accelerator designs that switch modes at layer or tile granularity suffer from low PE utilization since one core type idles whenever the other is active. NeuroFlex is the first accelerator to assign every output element independently to ANN or SNN execution mode with zero accuracy loss. We extend integer-exact ANN-SNN equivalence from layers to individual output elements, thereby enabling mode switching with no conversion error. An offline cost-guided scheduler scores each element by its marginal energy-delay trade-off and packs work across PEs, achieving 97-99% PE utilization compared to 40-45% for layer-wise hybrids. NeuroFlex reduces EDP by 57-67% over a strong ANN-only baseline and delivers up to 2.5x speedup over a dual-sparse SNN-only baseline. Our cost-guided scheduler improves throughput by 16-19% over random element assignment across vision, language, and transformer workloads.

For deep learning problems on graph-structured data, pooling layers are important for down sampling, reducing computational cost, and to minimize overfitting. We define a pooling layer, nervePool, for data structured as simplicial complexes, which are generalizations of graphs that include higher-dimensional simplices beyond vertices and edges; this structure allows for greater flexibility in modeling higher-order relationships. The proposed simplicial coarsening scheme is built upon partitions of vertices, which allow us to generate hierarchical representations of simplicial complexes, collapsing information in a learned fashion. NervePool builds on the learned vertex cluster assignments and extends to coarsening of higher dimensional simplices in a deterministic fashion. While in practice the pooling operations are computed via a series of matrix operations, the topological motivation is a set-theoretic construction based on unions of stars of simplices and the nerve complex.