Overview

Diffusion models learn a data distribution by gradually corrupting examples with noise and training a denoiser to reverse that process. Major approaches include DDPMs and score-based SDEs, latent diffusion and diffusion Transformers, flow and consistency methods, and discrete masked or continuous-time Markov diffusion; conditioning and guidance adapt them to specific tasks. They are used for images, video, audio, language, molecules, and scientific forecasting, with evaluations ranging from ImageNet FID to language perplexity and domain-specific measures of accuracy and uncertainty. A central tension is how to make sampling faster and generation more controllable without sacrificing quality, calibration, or diversity, while theory and ongoing audits address generalization, memorization, and privacy.

Latest papers

1,192 papers152 papers in the last four weeks, up 77% on the four weeks before. 0.9% of all new papers.

Mar 2, 2026

DreamReader: An Interpretability Toolkit for Text-to-Image Models

Despite the rapid adoption of text-to-image (T2I) diffusion models, causal and representation-level analysis remains fragmented and largely limited to isolated probing techniques. To address this gap, we introduce DreamReader: a unified framework that formalizes diffusion interpretability as composable representation operators spanning activation extraction, causal patching, structured ablations, and activation steering across modules and timesteps. DreamReader provides a model-agnostic abstraction layer enabling systematic analysis and intervention across diffusion architectures. Beyond consolidating existing methods, DreamReader introduces three novel intervention primitives for diffusion models: (1) representation fine-tuning (LoReFT) for subspace-constrained internal adaptation; (2) classifier-guided gradient steering using MLP probes trained on activations; and (3) component-level cross-model mapping for systematic study of transferability of representations across modalities. These mechanisms allows us to do lightweight white-box interventions on T2I models by drawing inspiration from interpretability techniques on LLMs. We demonstrate DreamReader through controlled experiments that (i) perform activation stitching between two models, and (ii) apply LoReFT to steer multiple activation units, reliably injecting a target concept into the generated images. Experiments are specified declaratively and executed in controlled batched pipelines to enable reproducible large-scale analysis. Across multiple case studies, we show that techniques adapted from language model interpretability yield promising and controllable interventions in diffusion models. DreamReader is released as an open source toolkit for advancing research on T2I interpretability.
Mar 1, 2026

Data-Efficient Brushstroke Generation with Diffusion Models for Oil Painting

Many creative multimedia systems are built upon visual primitives such as strokes or textures, which are difficult to collect at scale and fundamentally different from natural image data. This data scarcity makes it challenging for modern generative models to learn expressive and controllable primitives, limiting their use in process-aware content creation. In this work, we study the problem of learning human-like brushstroke generation from a small set of hand-drawn samples (n=470) and propose StrokeDiff, a diffusion-based framework with Smooth Regularization (SmR). SmR injects stochastic visual priors during training, providing a simple mechanism to stabilize diffusion models under sparse supervision without altering the inference process. We further show how the learned primitives can be made controllable through a Bézier-based conditioning module and integrated into a complete stroke-based painting pipeline, including prediction, generation, ordering, and compositing. This demonstrates how data-efficient primitive modeling can support expressive and structured multimedia content creation. Experiments indicate that the proposed approach produces diverse and structurally coherent brushstrokes and enables paintings with richer texture and layering, validated by both automatic metrics and human evaluation.
Mar 1, 2026

LLaDA-o: An Effective and Length-Adaptive Omni Diffusion Model

We present LLaDA-o, an effective and length-adaptive omni diffusion model for multimodal understanding and generation. LLaDA-o is built on a Mixture of Diffusion (MoD) framework that decouples discrete masked diffusion for text understanding and continuous diffusion for visual generation, while coupling them through a shared, simple, and efficient attention backbone that reduces redundant computation for fixed conditions. Building on MoD, we further introduce a data-centric length adaptation strategy that enables flexible-length decoding in multimodal settings without architectural changes. Extensive experiments show that LLaDA-o achieves state-of-the-art performance among omni-diffusion models on multimodal understanding and generation benchmarks, and reaches 87.04 on DPG-Bench for text-to-image generation, supporting the effectiveness of unified omni diffusion modeling. Code is available at https://github.com/ML-GSAI/LLaDA-o.
Mar 1, 2026

BadRSSD: Backdoor Attacks on Regularized Self-Supervised Diffusion Models

Self-supervised diffusion models learn high-quality visual representations via latent space denoising. However, their representation layer poses a distinct threat: unlike traditional attacks targeting generative outputs, its unconstrained latent semantic space allows for stealthy backdoors, permitting malicious control upon triggering. In this paper, we propose BadRSSD, the first backdoor attack targeting the representation layer of self-supervised diffusion models. Specifically, it hijacks the semantic representations of poisoned samples with triggers in Principal Component Analysis (PCA) space toward those of a target image, then controls the denoising trajectory during diffusion by applying coordinated constraints across latent, pixel, and feature distribution spaces to steer the model toward generating the specified target. Additionally, we integrate representation dispersion regularization into the constraint framework to maintain feature space uniformity, significantly enhancing attack stealth. This approach preserves normal model functionality (high utility) while achieving precise target generation upon trigger activation (high specificity). Experiments on multiple benchmark datasets demonstrate that BadRSSD substantially outperforms existing attacks in both FID and MSE metrics, reliably establishing backdoors across different architectures and configurations, and effectively resisting state-of-the-art backdoor defenses.
Mar 1, 2026

Mobile-VTON: High-Fidelity On-Device Virtual Try-On

Virtual try-on (VTON) has recently achieved impressive visual fidelity, but most existing systems require uploading personal photos to cloud-based GPUs, raising privacy concerns and limiting on-device deployment. To address this, we present Mobile-VTON, a high-quality, privacy-preserving framework that enables fully offline virtual try-on on commodity mobile devices using only a single user image and a garment image. Mobile-VTON introduces a modular TeacherNet-GarmentNet-TryonNet (TGT) architecture that integrates knowledge distillation, garment-conditioned generation, and garment alignment into a unified pipeline optimized for on-device efficiency. Within this framework, we propose a Feature-Guided Adversarial (FGA) Distillation strategy that combines teacher supervision with adversarial learning to better match real-world image distributions. GarmentNet is trained with a trajectory-consistency loss to preserve garment semantics across diffusion steps, while TryonNet uses latent concatenation and lightweight cross-modal conditioning to enable robust garment-to-person alignment without large-scale pretraining. By combining these components, Mobile-VTON achieves high-fidelity generation with low computational overhead. Experiments on VITON-HD and DressCode at 1024 x 768 show that it matches or outperforms strong server-based baselines while running entirely offline. These results demonstrate that high-quality VTON is not only feasible but also practical on-device, offering a secure solution for real-world applications. Code and project page are available at https://zhenchenwan.github.io/Mobile-VTON/.
Feb 28, 2026

Stroke outcome and evolution prediction from CT brain using a spatiotemporal diffusion autoencoder

Stroke is a major cause of death and disability worldwide. Accurate outcome and evolution prediction has the potential to revolutionize stroke care by individualizing clinical decision-making leading to better outcomes. However, despite a plethora of attempts and the rich data provided by neuroimaging, modelling the ultimate fate of brain tissue remains a challenging task. In this work, we apply recent ideas in the field of diffusion probabilistic models to generate a self-supervised semantically meaningful stroke representation from Computed Tomography (CT) images. We then improve this representation by extending the method to accommodate longitudinal images and the time from stroke onset. The effectiveness of our approach is evaluated on a dataset consisting of 5,824 CT images from 3,573 patients across two medical centers with minimal labels. Comparative experiments show that our method achieves the best performance for predicting next-day severity and functional outcome at discharge.
Feb 28, 2026

Efficient Long-Sequence Diffusion Modeling for Symbolic Music Generation

Symbolic music generation is a challenging task in multimedia generation, involving long sequences with hierarchical temporal structures, long-range dependencies, and fine-grained local details. Though recent diffusion-based models produce high quality generations, they tend to suffer from high training and inference costs with long symbolic sequences due to iterative denoising and sequence-length-related costs. To deal with such problem, we put forth a diffusing strategy named SMDIM to combine efficient global structure construction and light local refinement. SMDIM uses structured state space models to capture long range musical context at near linear cost, and selectively refines local musical details via a hybrid refinement scheme. Experiments performed on a wide range of symbolic music datasets which encompass various Western classical music, popular music and traditional folk music show that the SMDIM model outperforms the other state-of-the-art approaches on both the generation quality and the computational efficiency, and it has robust generalization to underexplored musical styles. These results show that SMDIM offers a principled solution for long-sequence symbolic music generation, including associated attributes that accompany the sequences. We provide a project webpage with audio examples and supplementary materials at https://3328702107.github.io/smdim-music/.
Feb 28, 2026

Jano: Adaptive Diffusion Generation with Early-stage Convergence Awareness

Diffusion models have achieved remarkable success in generative AI, yet their computational efficiency remains a significant challenge, particularly for Diffusion Transformers (DiTs) requiring intensive full-attention computation. While existing acceleration approaches focus on content-agnostic uniform optimization strategies, we observe that different regions in generated content exhibit heterogeneous convergence patterns during the denoising process. We present Jano, a training-free framework that leverages this insight for efficient region-aware generation. Jano introduces an early-stage complexity recognition algorithm that accurately identifies regional convergence requirements within initial denoising steps, coupled with an adaptive token scheduling runtime that optimizes computational resource allocation. Through comprehensive evaluation on state-of-the-art models, Jano achieves substantial acceleration (average 2.0 times speedup, up to 2.4 times) while preserving generation quality. Our work challenges conventional uniform processing assumptions and provides a practical solution for accelerating large-scale content generation. The source code of our implementation is available at https://github.com/chen-yy20/Jano.
Feb 28, 2026

Roots Beneath the Cut: Uncovering the Risk of Concept Revival in Pruning-Based Unlearning for Diffusion Models

Pruning-based unlearning has recently emerged as a fast, training-free, and data-independent approach to remove undesired concepts from diffusion models. It promises high efficiency and robustness, offering an attractive alternative to traditional fine-tuning or editing-based unlearning. However, in this paper we uncover a hidden danger behind this promising paradigm. We find that the locations of pruned weights, typically set to zero during unlearning, can act as side-channel signals that leak critical information about the erased concepts. To verify this vulnerability, we design a novel attack framework capable of reviving erased concepts from pruned diffusion models in a fully data-free and training-free manner. Our experiments confirm that pruning-based unlearning is not inherently secure, as erased concepts can be effectively revived without any additional data or retraining. Extensive experiments on diffusion-based unlearning based on concept related weights lead to the conclusion: once the critical concept-related weights in diffusion models are identified, our method can effectively recover the original concept regardless of how the weights are manipulated. Finally, we explore potential defense strategies and advocate safer pruning mechanisms that conceal pruning locations while preserving unlearning effectiveness, providing practical insights for designing more secure pruning-based unlearning frameworks.
Feb 27, 2026

Do Diffusion Models Dream of Electric Planes? Discrete and Continuous Simulation-Based Inference for Aircraft Design

In this paper, we generate conceptual engineering designs of electric vertical take-off and landing (eVTOL) aircraft. We follow the paradigm of simulation-based inference (SBI), whereby we look to learn a posterior distribution over the full eVTOL design space. To learn this distribution, we sample over discrete aircraft configurations (topologies) and their corresponding set of continuous parameters. Therefore, we introduce a hierarchical probabilistic model consisting of two diffusion models. The first model leverages recent work on Riemannian Diffusion Language Modeling (RDLM) and Unified World Models (UWMs) to enable us to sample topologies from a discrete and continuous space. For the second model we introduce a masked diffusion approach to sample the corresponding parameters conditioned on the topology. Our approach rediscovers known trends and governing physical laws in aircraft design, while significantly accelerating design generation.
Feb 27, 2026

GeoDiff4D: Geometry-Aware Diffusion for 4D Head Avatar Reconstruction

Reconstructing photorealistic and animatable 4D head avatars from a single portrait image remains a fundamental challenge in computer vision. While diffusion models have enabled remarkable progress in image and video generation for avatar reconstruction, existing methods primarily rely on 2D priors and struggle to achieve consistent 3D geometry. We propose a novel framework that leverages geometry-aware diffusion to learn strong geometry priors for high-fidelity head avatar reconstruction. Our approach jointly synthesizes portrait images and corresponding surface normals, while a pose-free expression encoder captures implicit expression representations. Both synthesized images and expression latents are incorporated into 3D Gaussian-based avatars, enabling photorealistic rendering with accurate geometry. Extensive experiments demonstrate that our method substantially outperforms state-of-the-art approaches in visual quality, expression fidelity, and cross-identity generalization, while supporting real-time rendering.
Feb 27, 2026

Ordinal Diffusion Models for Color Fundus Images

Generative image models such as diffusion models can improve performance on clinically relevant tasks by offering deep learning models supplementary training data. However, most conditional diffusion models treat disease stages as independent classes, ignoring the continuous nature of disease progression. This mismatch is problematic in medical imaging because continuous pathological processes are typically only observed through coarse, discrete but ordered labels as in ophthalmology for diabetic retinopathy (DR). We propose an ordinal latent diffusion model for generating color fundus images that explicitly incorporates the ordered structure of DR severity into the generation process. Instead of categorical conditioning, we used a scalar disease representation, enabling a smooth transition between adjacent stages. We evaluated our approach using visual realism metrics and classification-based clinical consistency analysis on the EyePACS dataset. Compared to a standard conditional diffusion model, our model reduced the Fréchet inception distance for four of the five DR stages and increased the quadratic weighted κκ from 0.79 to 0.87. Furthermore, interpolation experiments showed that the model captured a continuous spectrum of disease progression learned from ordered, coarse class labels. Code available at https://github.com/berenslab/OrdinalDiffusionModels.
Feb 27, 2026

Diffusion Probe: Generated Image Result Prediction Using CNN Probes

Text-to-image (T2I) diffusion models lack an efficient mechanism for early quality assessment, leading to costly trial-and-error in multi-generation scenarios such as prompt iteration, agent-based generation, and flow-grpo. We reveal a strong correlation between early diffusion cross-attention distributions and final image quality. Based on this finding, we introduce Diffusion Probe, a framework that leverages internal cross-attention maps as predictive signals. We design a lightweight predictor that maps statistical properties of early-stage cross-attention extracted from initial denoising steps to the final image's overall quality. This enables accurate forecasting of image quality across diverse evaluation metrics long before full synthesis is complete. We validate Diffusion Probe across a wide range of settings. On multiple T2I models, across early denoising windows, resolutions, and quality metrics, it achieves strong correlation (PCC > 0.7) and high classification performance (AUC-ROC > 0.9). Its reliability translates into practical gains. By enabling early quality-aware decisions in workflows such as prompt optimization, seed selection, and accelerated RL training, the probe supports more targeted sampling and avoids computation on low-potential generations. This reduces computational overhead while improving final output quality. Diffusion Probe is model-agnostic, efficient, and broadly applicable, offering a practical solution for improving T2I generation efficiency through early quality prediction. Code: https://github.com/Alibaba-VELLDEPTH/DiffusionProbe
Feb 27, 2026

Selective Denoising Diffusion Model for Time Series Anomaly Detection

Time series anomaly detection (TSAD) has been an important area of research for decades, with reconstruction-based methods, mostly based on generative models, gaining popularity and demonstrating success. Diffusion models have recently attracted attention due to their advanced generative capabilities. Existing diffusion-based methods for TSAD rely on a conditional strategy, which reconstructs input instances from white noise with the aid of the conditioner. However, this poses challenges in accurately reconstructing the normal parts, resulting in suboptimal detection performance. In response, we propose a novel diffusion-based method, named AnomalyFilter, which acts as a selective filter that only denoises anomaly parts in the instance while retaining normal parts. To build such a filter, we mask Gaussian noise during the training phase and conduct the denoising process without adding noise to the instances. The synergy of the two simple components greatly enhances the performance of naive diffusion models. Extensive experiments on five datasets demonstrate that AnomalyFilter achieves notably low reconstruction error on normal parts, providing empirical support for its effectiveness in anomaly detection. AnomalyFilter represents a pioneering approach that focuses on the noise design of diffusion models specifically tailored for TSAD.
Feb 27, 2026

BuildAnyPoint: 3D Building Structured Abstraction from Diverse Point Clouds

We introduce BuildAnyPoint, a novel generative framework for structured 3D building reconstruction from point clouds with diverse distributions, such as those captured by airborne LiDAR and Structure-from-Motion. To recover artist-created building abstraction in this highly underconstrained setting, we capitalize on the role of explicit 3D generative priors in autoregressive mesh generation. Specifically, we design a Loosely Cascaded Diffusion Transformer (Loca-DiT) that initially recovers the underlying distribution from noisy or sparse points, followed by autoregressively encapsulating them into compact meshes. We first formulate distribution recovery as a conditional generation task by training latent diffusion models conditioned on input point clouds, and then tailor a decoder-only transformer for conditional autoregressive mesh generation based on the recovered point clouds. Our method delivers substantial qualitative and quantitative improvements over prior building abstraction methods. Furthermore, the effectiveness of our approach is evidenced by the strong performance of its recovered point clouds on building point cloud completion benchmarks, which exhibit improved surface accuracy and distribution uniformity.
Feb 26, 2026

SALIENT: Frequency-Aware Paired Diffusion for Controllable Long-Tail CT Detection

Detection of rare lesions in whole-body CT is fundamentally limited by extreme class imbalance and low target-to-volume ratios, producing precision collapse despite high AUROC. Synthetic augmentation with diffusion models offers promise, yet pixel-space diffusion is computationally expensive, and existing mask-conditioned approaches lack controllable attribute-level regulation and paired supervision for accountable training. We introduce SALIENT, a mask-conditioned wavelet-domain diffusion framework that synthesizes paired lesion-masking volumes for controllable CT augmentation under long-tail regimes. Instead of denoising in pixel space, SALIENT performs structured diffusion over discrete wavelet coefficients, explicitly separating low-frequency brightness from high-frequency structural detail. Learnable frequency-aware objectives disentangle target and background attributes (structure, contrast, edge fidelity), enabling interpretable and stable optimization. A 3D VAE generates diverse volumetric lesion masks, and a semi-supervised teacher produces paired slice-level pseudo-labels for downstream mask-guided detection. SALIENT improves generative realism, as reflected by higher MS-SSIM (0.63 to 0.83) and lower FID (118.4 to 46.5). In a separate downstream evaluation, SALIENT-augmented training improves long-tail detection performance, yielding disproportionate AUPRC gains across low prevalences and target-to-volume ratios. Optimal synthetic ratios shift from 2x to 4x as labeled seed size decreases, indicating a seed-dependent augmentation regime under low-label conditions. SALIENT demonstrates that frequency-aware diffusion enables controllable, computationally efficient precision rescue in long-tail CT detection.
Feb 26, 2026

Face Time Traveller : Travel Through Ages Without Losing Identity

Face aging, an ill-posed problem shaped by environmental and genetic factors, is vital in entertainment, forensics, and digital archiving, where realistic age transformations must preserve both identity and visual realism. However, existing works relying on numerical age representations overlook the interplay of biological and contextual cues. Despite progress in recent face aging models, they struggle with identity preservation in wide age transformations, also static attention and optimization-heavy inversion in diffusion limit adaptability, fine-grained control and background consistency. To address these challenges, we propose Face Time Traveller (FaceTT), a diffusion-based framework that achieves high-fidelity, identity-consistent age transformation. Here, we introduce a Face-Attribute-Aware Prompt Refinement strategy that encodes intrinsic (biological) and extrinsic (environmental) aging cues for context-aware conditioning. A tuning-free Angular Inversion method is proposed that efficiently maps real faces into the diffusion latent space for fast and accurate reconstruction. Moreover, an Adaptive Attention Control mechanism is introduced that dynamically balances cross-attention for semantic aging cues and self-attention for structural and identity preservation. Extensive experiments on benchmark datasets and in-the-wild testset demonstrate that FaceTT achieves superior identity retention, background preservation and aging realism over state-of-the-art (SOTA) methods.
Feb 26, 2026

Causal Motion Diffusion Models for Autoregressive Motion Generation

Recent advances in motion diffusion models have substantially improved the realism of human motion synthesis. However, existing approaches either rely on full-sequence diffusion models with bidirectional generation, which limits temporal causality and real-time applicability, or autoregressive models that suffer from instability and cumulative errors. In this work, we present Causal Motion Diffusion Models (CMDM), a unified framework for autoregressive motion generation based on a causal diffusion transformer that operates in a semantically aligned latent space. CMDM builds upon a Motion-Language-Aligned Causal VAE (MAC-VAE), which encodes motion sequences into temporally causal latent representations. On top of this latent representation, an autoregressive diffusion transformer is trained using causal diffusion forcing to perform temporally ordered denoising across motion frames. To achieve fast inference, we introduce a frame-wise sampling schedule with causal uncertainty, where each subsequent frame is predicted from partially denoised previous frames. The resulting framework supports high-quality text-to-motion generation, streaming synthesis, and long-horizon motion generation at interactive rates. Experiments on HumanML3D and SnapMoGen demonstrate that CMDM outperforms existing diffusion and autoregressive models in both semantic fidelity and temporal smoothness, while substantially reducing inference latency.
Feb 25, 2026

Absorbing Discrete Diffusion for Speech Enhancement

Inspired by recent developments in neural speech coding and diffusion-based language modeling, we tackle speech enhancement by modeling the conditional distribution of clean speech codes given noisy speech codes using absorbing discrete diffusion. The proposed approach, which we call ADDSE, leverages both the expressive latent space of neural audio codecs and the non-autoregressive sampling procedure of diffusion models. To efficiently model the hierarchical structure of residual vector quantization codes, we propose RQDiT, which combines techniques from RQ-Transformer and diffusion Transformers for non-autoregressive modeling. Results show competitive performance in terms of non-intrusive objective metrics on two datasets, especially at low signal-to-noise ratios and with few sampling steps. Code and audio examples are available online.
Feb 25, 2026

Probing the Geometry of Diffusion Models with the String Method

Understanding the geometry of learned distributions is fundamental to improving and interpreting diffusion models, yet systematic tools for exploring their landscape remain limited. Standard latent-space interpolations fail to respect the structure of the learned distribution, often traversing low-density regions. We introduce a framework based on the string method that computes continuous paths between samples by evolving curves under the learned score function. Operating on pretrained models without retraining, our approach interpolates between three regimes: pure generative transport, which yields continuous sample paths; gradient-dominated dynamics, which recover minimum energy paths (MEPs); and finite-temperature string dynamics, which compute principal curves -- self-consistent paths that balance energy and entropy. We demonstrate that the choice of regime matters in practice. For image diffusion models, MEPs contain high-likelihood but unrealistic ''cartoon'' images, confirming prior observations that likelihood maxima appear unrealistic; principal curves instead yield realistic morphing sequences despite lower likelihood. For protein structure prediction, our method computes transition pathways between metastable conformers directly from models trained on static structures, yielding paths with physically plausible intermediates. Together, these results establish the string method as a principled tool for probing the modal structure of diffusion models -- identifying modes, characterizing barriers, and mapping connectivity in complex learned distributions.
Feb 25, 2026

Learning Quantum Data Distribution via Chaotic Quantum Diffusion Model

Generative models for quantum data pose significant challenges but hold immense potential in fields such as chemoinformatics and quantum physics. Quantum denoising diffusion probabilistic models (QuDDPMs) enable efficient learning of quantum data distributions by progressively scrambling and denoising quantum states. However, existing implementations typically rely on circuit-based random unitary dynamics, which can be costly to implement and sensitive to control imperfections, particularly on analog quantum hardware. We propose the chaotic quantum diffusion model, a framework that generates projected ensembles via chaotic Hamiltonian time evolution, providing a flexible and hardware-compatible diffusion mechanism. Requiring only global, time-independent control, our approach substantially reduces implementation overhead across diverse analog quantum platforms while achieving accuracy comparable to QuDDPMs. This method improves trainability and robustness, broadening the applicability of quantum generative modeling.
Feb 25, 2026

EndoDDC: Learning Sparse to Dense Reconstruction for Endoscopic Robotic Navigation via Diffusion Depth Completion

Accurate depth estimation plays a critical role in the navigation of endoscopic surgical robots, forming the foundation for 3D reconstruction and safe instrument guidance. Fine-tuning pretrained models heavily relies on endoscopic surgical datasets with precise depth annotations. While existing self-supervised depth estimation techniques eliminate the need for accurate depth annotations, their performance degrades in environments with weak textures and variable lighting, leading to sparse reconstruction with invalid depth estimation. Depth completion using sparse depth maps can mitigate these issues and improve accuracy. Despite the advances in depth completion techniques in general fields, their application in endoscopy remains limited. To overcome these limitations, we propose EndoDDC, an endoscopy depth completion method that integrates images, sparse depth information with depth gradient features, and optimizes depth maps through a diffusion model, addressing the issues of weak texture and light reflection in endoscopic environments. Extensive experiments on two publicly available endoscopy datasets show that our approach outperforms state-of-the-art models in both depth accuracy and robustness. This demonstrates the potential of our method to reduce visual errors in complex endoscopic environments. Our code will be released at https://github.com/yinheng-lin/EndoDDC.
Feb 25, 2026

The Design Space of Tri-Modal Masked Diffusion Models

Discrete diffusion models have emerged as strong alternatives to autoregressive language models, with recent work initializing and fine-tuning a base unimodal model for bimodal generation. Diverging from previous approaches, we introduce the first tri-modal masked diffusion model pretrained from scratch on text, image-text, and audio-text data. We systematically analyze multimodal scaling laws, modality mixing ratios, noise schedules, and batch-size effects, and we provide optimized inference sampling defaults. Our batch-size analysis yields a novel stochastic differential equation (SDE)-based reparameterization that eliminates the need for tuning the optimal batch size as reported in recent work. This reparameterization decouples the physical batch size, often chosen based on compute constraints (GPU saturation, FLOP efficiency, wall-clock time), from the logical batch size, chosen to balance gradient variance during stochastic optimization. Finally, we pretrain a preliminary 3B-parameter tri-modal model on 6.4T tokens, demonstrating the capabilities of a unified design and achieving strong results in text generation, text-to-image tasks, and text-to-speech tasks. Our work represents the largest-scale systematic open study of multimodal discrete diffusion models conducted to date, providing insights into scaling behaviors across multiple modalities.
Feb 24, 2026

RelA-Diffusion: Relativistic Adversarial Diffusion for Multi-Tracer PET Synthesis from Multi-Sequence MRI

Multi-tracer positron emission tomography (PET) provides critical insights into diverse neuropathological processes such as tau accumulation, neuroinflammation, and ββ-amyloid deposition in the brain, making it indispensable for comprehensive neurological assessment. However, routine acquisition of multi-tracer PET is limited by high costs, radiation exposure, and restricted tracer availability. Recent efforts have explored deep learning approaches for synthesizing PET images from structural MRI. While some methods rely solely on T1-weighted MRI, others incorporate additional sequences such as T2-FLAIR to improve pathological sensitivity. However, existing methods often struggle to capture fine-grained anatomical and pathological details, resulting in artifacts and unrealistic outputs. To this end, we propose RelA-Diffusion, a Relativistic Adversarial Diffusion framework for multi-tracer PET synthesis from multi-sequence MRI. By leveraging both T1-weighted and T2-FLAIR scans as complementary inputs, RelA-Diffusion captures richer structural information to guide image generation. To improve synthesis fidelity, we introduce a gradient-penalized relativistic adversarial loss to the intermediate clean predictions of the diffusion model. This loss compares real and generated images in a relative manner, encouraging the synthesis of more realistic local structures. Both the relativistic formulation and the gradient penalty contribute to stabilizing the training, while adversarial feedback at each diffusion timestep enables consistent refinement throughout the generation process. Extensive experiments on two datasets demonstrate that RelA-Diffusion outperforms existing methods in both visual fidelity and quantitative metrics, highlighting its potential for accurate synthesis of multi-tracer PET.
Feb 24, 2026

The Diffusion Duality, Chapter II: ΨΨ-Samplers

Uniform-state discrete diffusion models excel at few-step generation and guidance due to their ability to self-correct, making them preferred over autoregressive or Masked diffusion models in these settings. However, their sampling quality plateaus with ancestral samplers as the number of steps increases. We introduce a family of Predictor-Corrector (PC) samplers for discrete diffusion that generalize prior methods and apply to arbitrary noise processes. When paired with uniform-state diffusion, our samplers outperform ancestral sampling on both language and image modeling, achieving lower generative perplexity at matched unigram entropy on OpenWebText and better FID/IS scores on CIFAR10. Crucially, unlike conventional samplers, our PC methods continue to improve with more sampling steps. Taken together, these findings call into question the assumption that Masked diffusion is the inevitable future of diffusion-based language modeling. Beyond sampling, we develop a memory-efficient curriculum for the Gaussian relaxation training phase, reducing training time by 25% and memory by 33% compared to Duo while maintaining comparable perplexity on OpenWebText and LM1B and strong downstream performance. We release code, checkpoints, and a video-tutorial on: https://s-sahoo.com/duo-ch2
Feb 24, 2026

OrthoDiffusion: A Generalizable Multi-Task Diffusion Foundation Model for Musculoskeletal MRI Interpretation

Musculoskeletal disorders represent a significant global health burden and are a leading cause of disability worldwide. While MRI is essential for accurate diagnosis, its interpretation remains exceptionally challenging. Radiologists must identify multiple potential abnormalities within complex anatomical structures across different imaging planes, a process that requires significant expertise and is prone to variability. We developed OrthoDiffusion, a unified diffusion-based foundation model designed for multi-task musculoskeletal MRI interpretation. The framework utilizes three orientation-specific 3D diffusion models, pre-trained in a self-supervised manner on 15,948 unlabeled knee MRI scans, to learn robust anatomical features from sagittal, coronal, and axial views. These view-specific representations are integrated to support diverse clinical tasks, including anatomical segmentation and multi-label diagnosis. Our evaluation demonstrates that OrthoDiffusion achieves excellent performance in the segmentation of 11 knee structures and the detection of 8 knee abnormalities. The model exhibited remarkable robustness across different clinical centers and MRI field strengths, consistently outperforming traditional supervised models. Notably, in settings where labeled data was scarce, OrthoDiffusion maintained high diagnostic precision using only 10% of training labels. Furthermore, the anatomical representations learned from knee imaging proved highly transferable to other joints, achieving strong diagnostic performance across 11 diseases of the ankle and shoulder. These findings suggest that diffusion-based foundation models can serve as a unified platform for multi-disease diagnosis and anatomical segmentation, potentially improving the efficiency and accuracy of musculoskeletal MRI interpretation in real-world clinical workflows.
Feb 24, 2026

Sample-efficient evidence estimation of score based priors for model selection

The choice of prior is central to solving ill-posed imaging inverse problems, making it essential to select one consistent with the measurements yy to avoid severe bias. In Bayesian inverse problems, this could be achieved by evaluating the model evidence p(y∣M)p(y \mid M) under different models MM that specify the prior and then selecting the one with the highest value. Diffusion models are the state-of-the-art approach to solving inverse problems with a data-driven prior; however, directly computing the model evidence with respect to a diffusion prior is intractable. Furthermore, most existing model evidence estimators require either many pointwise evaluations of the unnormalized prior density or an accurate clean prior score. We propose DiME, an estimator of the model evidence of a diffusion prior by integrating over the time-marginals of posterior sampling methods. Our method leverages the large amount of intermediate samples naturally obtained during the reverse diffusion sampling process to obtain an accurate estimation of the model evidence using only a handful of posterior samples (e.g., 20). We also demonstrate how to implement our estimator in tandem with recent diffusion posterior sampling methods. Empirically, our estimator matches the model evidence when it can be computed analytically, and it is able to both select the correct diffusion model prior and diagnose prior misfit under different highly ill-conditioned, non-linear inverse problems, including a real-world black hole imaging problem.
Feb 24, 2026

LESA: Learnable Stage-Aware Predictors for Diffusion Model Acceleration

Diffusion models have achieved remarkable success in image and video generation tasks. However, the high computational demands of Diffusion Transformers (DiTs) pose a significant challenge to their practical deployment. While feature caching is a promising acceleration strategy, existing methods based on simple reusing or training-free forecasting struggle to adapt to the complex, stage-dependent dynamics of the diffusion process, often resulting in quality degradation and failing to maintain consistency with the standard denoising process. To address this, we propose a LEarnable Stage-Aware (LESA) predictor framework based on two-stage training. Our approach leverages a Kolmogorov-Arnold Network (KAN) to accurately learn temporal feature mappings from data. We further introduce a multi-stage, multi-expert architecture that assigns specialized predictors to different noise-level stages, enabling more precise and robust feature forecasting. Extensive experiments show our method achieves significant acceleration while maintaining high-fidelity generation. Experiments demonstrate 5.00x acceleration on FLUX.1-dev with minimal quality degradation (1.0% drop), 6.25x speedup on Qwen-Image with a 20.2% quality improvement over the previous SOTA (TaylorSeer), and 5.00x acceleration on HunyuanVideo with a 24.7% PSNR improvement over TaylorSeer. State-of-the-art performance on both text-to-image and text-to-video synthesis validates the effectiveness and generalization capability of our training-based framework across different models. Our code is available at https://github.com/caipeiliang2004/LESA.
Feb 23, 2026

Mean-Field Path-Integral Diffusion: From Samples to Interacting Agents

Independent sample generation is the prevailing paradigm in modern diffusion-based generative models of AI. We ask a different question: can samples coordinate through shared population statistics to transport probability mass more efficiently? We introduce Mean-Field Path-Integral Diffusion (MF-PID), a framework in which samples are promoted to interacting agents whose drift depends self-consistently on the evolving population density. The coupling converts distribution matching into a McKean--Vlasov extension of the stochastic optimal transport problem, unifying generative modeling and multi-agent control under the same Hamilton--Jacobi--Bellman/Kolmogorov--Fokker--Planck duality. We identify two analytically tractable regimes: a Linear--Quadratic--Gaussian (LQG) benchmark in which the infinite-dimensional mean-field system reduces to a finite set of Riccati and linear ODEs, and a Gaussian-mixture regime governed by a piecewise-constant protocol that preserves closed-form solvability. For a quadratic interaction potential with schedule βtβ_t and zero base drift we prove that the self-consistent MF guidance is the exact linear interpolant between initial and target global means -- a result that holds for arbitrary initial and target densities and any βtβ_t. Applied to demand-response control of energy systems, where agents aggregated into an ensemble are energy consumers (e.g.\ thermal zones within a building), MF-PID achieves 19--24% reductions in cumulative control energy over independent-agent baselines while matching the prescribed terminal distribution exactly, and reveals how coordination redistributes actuation effort across heterogeneous sub-populations.
Feb 23, 2026

Discrete Diffusion with Sample-Efficient Estimators for Conditionals

We study a discrete denoising diffusion framework that integrates a sample-efficient estimator of single-site conditionals with round-robin noising and denoising dynamics for generative modeling over discrete state spaces. Rather than approximating a discrete analog of a score function, our formulation treats single-site conditional probabilities as the fundamental objects that parameterize the reverse diffusion process. We employ a sample-efficient method known as Neural Interaction Screening Estimator (NeurISE) to estimate these conditionals in the diffusion dynamics. Controlled experiments on synthetic Ising models, MNIST, and scientific data sets produced by a D-Wave quantum annealer, synthetic Potts model and one dimensional quantum systems demonstrate the proposed approach. On the binary data sets, these experiments demonstrate that the proposed approach outperforms popular existing methods including ratio-based approaches, achieving improved performance in total variation, cross-correlations, and kernel density estimation metrics.