Image Segmentation
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13 papers in the last four weeks, up 44% on the four weeks before. 0.1% of all new papers.
Latest papers 305
Accurate medical image segmentation requires both long-range contextual reasoning and precise boundary delineation, a task where existing transformer- and diffusion-based paradigms are frequently bottlenecked by quadratic computational complexity and prohibitive inference latency. We propose RF-HiT, a Rectified Flow Hierarchical Transformer that integrates an Hourglass Transformer backbone with a multi-scale hierarchical encoder for anatomically guided feature conditioning. Unlike prior diffusion-based approaches that rely on hundreds of denoising steps, RF-HiT leverages rectified flow with efficient transformer blocks, achieving linear complexity and requiring only a few discretization steps. The model further fuses conditioning features at each resolution via learnable interpolation, enabling effective multi-scale feature integration with minimal computational overhead. As a result, RF-HiT achieves a strong efficiency-performance trade-off, requiring only 10.14 GFLOPs, 13.6M parameters, and inference in as few as 3 steps. Despite its compact design, RF-HiT attains 91.27% mean Dice on ACDC and 87.40% on BraTS 2021, achieving performance comparable to or exceeding that of significantly more intensive architectures. These results suggest that RF-HiT is a promising, computationally efficient foundation for clinical image segmentation.
CrossPan: A Comprehensive Benchmark for Cross-Sequence Pancreas MRI Segmentation and Generalization
Automatic pancreas segmentation is fundamental to abdominal MRI analysis, yet deep learning models trained on one MRI sequence often fail catastrophically when applied to another-a challenge that has received little systematic investigation. We introduce CrossPan, a multi-institutional benchmark comprising 1,386 3D scans across three routinely acquired sequences (T1-weighted, T2-weighted, and Out-of-Phase) from eight centers. Our experiments reveal three key findings. First, cross-sequence domain shifts are far more severe than cross-center variability: models achieving Dice scores above 0.85 in-domain collapse to near-zero (<0.02) when transferred across sequences. Second, state-of-the-art domain generalization methods provide negligible benefit under these physics-driven contrast inversions, whereas foundation models like MedSAM2 maintain moderate zero-shot performance through contrast-invariant shape priors. Third, semi-supervised learning offers gains only under stable intensity distributions and becomes unstable on sequences with high intra-organ variability. These results establish cross-sequence generalization-not model architecture or center diversity-as the primary barrier to clinically deployable pancreas MRI segmentation. Dataset and code are available at https://crosspan.netlify.app/.
Colour Extraction Pipeline for Odonates using Computer Vision
The correlation between insect morphological traits and climate has been documented in physiological studies, but such studies remain limited by the time-consuming nature of the data analysis. In particular, the open source datasets often lack annotations of species' morphological traits, making dedicated annotations campaigns necessary; these efforts are typically local in scale and costly. In this paper, we propose a pipeline to identify and segment body parts of Odonates (dragonflies and damselflies) using deep neural networks, with the ultimate goal of extracting body parts' colouration. The pipeline is trained on a limited annotated dataset and refined with pseudo supervised data. We show that, by using open source images from citizen science platforms, our approach can segment each visible subject (Odonates) into head, thorax, abdomen, and wings and then extract a colour palette for each body part. This will enable large-scale statistical analysis of ecological correlations (e.g., between colouration and climate change, habitat loss, or geolocation) which are crucial for quantifying and assessing ecosystem biodiversity status.
AnchorSeg: Language Grounded Query Banks for Reasoning Segmentation
Reasoning segmentation requires models to ground complex, implicit textual queries into precise pixel-level masks. Existing approaches rely on a single segmentation token , whose hidden state implicitly encodes both semantic reasoning and spatial localization, limiting the model's ability to explicitly disentangle what to segment from where to segment. We introduce AnchorSeg, which reformulates reasoning segmentation as a structured conditional generation process over image tokens, conditioned on language grounded query banks. Instead of compressing all semantic reasoning and spatial localization into a single embedding, AnchorSeg constructs an ordered sequence of query banks: latent reasoning tokens that capture intermediate semantic states, and a segmentation anchor token that provides explicit spatial grounding. We model spatial conditioning as a factorized distribution over image tokens, where the anchor query determines localization signals while contextual queries provide semantic modulation. To bridge token-level predictions and pixel-level supervision, we propose Token--Mask Cycle Consistency (TMCC), a bidirectional training objective that enforces alignment across resolutions. By explicitly decoupling spatial grounding from semantic reasoning through structured language grounded query banks, AnchorSeg achieves state-of-the-art results on ReasonSeg test set (67.7% gIoU and 68.1% cIoU). All code and models are publicly available at https://github.com/rui-qian/AnchorSeg.
DSA-CycleGAN: A Domain Shift Aware CycleGAN for Robust Multi-Stain Glomeruli Segmentation
A key challenge in segmentation in digital histopathology is inter- and intra-stain variations as it reduces model performance. Labelling each stain is expensive and time-consuming so methods using stain transfer via CycleGAN, have been developed for training multi-stain segmentation models using labels from a single stain. Nevertheless, CycleGAN tends to introduce noise during translation because of the one-to-many nature of some stain pairs, which conflicts with its cycle consistency loss. To address this, we propose the Domain Shift Aware CycleGAN, which reduces the presence of such noise. Furthermore, we evaluate several advances from the field of machine learning aimed at resolving similar problems and compare their effectiveness against DSA-CycleGAN in the context of multi-stain glomeruli segmentation. Experiments demonstrate that DSA-CycleGAN not only improves segmentation performance in glomeruli segmentation but also outperforms other methods in reducing noise. This is particularly evident when translating between biologically distinct stains. The code is publicly available at https://github.com/zeeshannisar/DSA-CycleGAN.
AgentRVOS for MeViS-Text Track of 5th PVUW Challenge: 3rd Method
This report describes a Ref-VOS pipeline centered on Sa2VA and organized with explicit agent roles. The key idea is that Sa2VA should provide the first dense semantic hypothesis, while an agent loop decides whether that hypothesis should be accepted, revised, or refined. The pipeline starts with a target-presence judgment stage. If the referred object does not exist in the video, the system directly outputs zero masks. Otherwise, Sa2VA receives the video and referring prompt and produces a coarse mask trajectory over the full video. This trajectory is treated as a semantic prior rather than a final answer. A planner agent decomposes the query, temporal partition agents identify informative blocks, scout agents search for anchor frames, and refinement agents convert reliable Sa2VA masks into boxes and points for SAM3 propagation. A critic scores candidate trajectories, a reflection controller repairs weak hypotheses, and a collaboration controller reconciles multiple agent branches. The result is a Ref-VOS system in which Sa2VA is responsible for dense grounded understanding, while the agent layer handles presence verification, temporal search, confidence-aware revision, and final mask refinement.
Is SAM3 ready for pathology segmentation?
Is Segment Anything Model 3 (SAM3) capable in segmenting Any Pathology Images? Digital pathology segmentation spans tissue-level and nuclei-level scales, where traditional methods often suffer from high annotation costs and poor generalization. SAM3 introduces Promptable Concept Segmentation, offering a potential automated interface via text prompts. With this work, we propose a systematic evaluation protocol to explore the capability space of SAM3 in a structured manner. Specifically, we evaluate SAM3 under different supervision settings including zero-shot, few-shot, and supervised with varying prompting strategies. Our extensive evaluation on pathological datasets including NuInsSeg, PanNuke and GlaS, reveals that: (1) text-only prompts poorly activate nuclear concepts; (2) performance is highly sensitive to visual prompt types and budgets; (3) few-shot learning offers gains, but SAM3 lacks robustness against visual prompt noise; and (4) a significant gap persists between prompt-based usage and task-trained adapter-based reference. Our study delineates SAM3's boundaries in pathology image segmentation and provides practical guidance on the necessity of pathology domain adaptation.
Sharpening Lightweight Models for Generalized Polyp Segmentation: A Boundary Guided Distillation from Foundation Models
Automated polyp segmentation is critical for early colorectal cancer detection and its prevention, yet remains challenging due to weak boundaries, large appearance variations, and limited annotated data. Lightweight segmentation models such as U-Net, U-Net++, and PraNet offer practical efficiency for clinical deployment but struggle to capture the rich semantic and structural cues required for accurate delineation of complex polyp regions. In contrast, large Vision Foundation Models (VFMs), including SAM, OneFormer, Mask2Former, and DINOv2, exhibit strong generalization but transfer poorly to polyp segmentation due to domain mismatch, insufficient boundary sensitivity, and high computational cost. To bridge this gap, we propose \textit{\textbf{LiteBounD}, a \underline{Li}gh\underline{t}w\underline{e}ight \underline{Boun}dary-guided \underline{D}istillation} framework that transfers complementary semantic and structural priors from multiple VFMs into compact segmentation backbones. LiteBounD introduces (i) a dual-path distillation mechanism that disentangles semantic and boundary-aware representations, (ii) a frequency-aware alignment strategy that supervises low-frequency global semantics and high-frequency boundary details separately, and (iii) a boundary-aware decoder that fuses multi-scale encoder features with distilled semantically rich boundary information for precise segmentation. Extensive experiments on both seen (Kvasir-SEG, CVC-ClinicDB) and unseen (ColonDB, CVC-300, ETIS) datasets demonstrate that LiteBounD consistently outperforms its lightweight baselines by a significant margin and achieves performance competitive with state-of-the-art methods, while maintaining the efficiency required for real-time clinical use. Our code is available at https://github.com/lostinrepo/LiteBounD.
SegTTA: Training-Free Test-Time Augmentation for Zero-Shot Medical Imaging Segmentation
Increasingly advanced data augmentation techniques have greatly aided clinical medical research, increasing data diversity and improving model generalization capabilities. Although most current basic models exhibit strong generalization abilities, image quality varies due to differences in equipment and operators. To address these challenges, we present SegTTA, a framework that improves medical image segmentation without model retraining by combining four augmentations (Gamma correction, Contrast enhancement, Gaussian blur, Gaussian noise) with weighted voting across multiple MedSAM2 checkpoints. Experiments demonstrate consistent improvements across three diverse datasets: healthy uterus segmentation, uterine myoma detection, and multi class hepatic structure segmentation. Ablation studies reveal that large organs benefit from intensity augmentations while small lesions require noise augmentations. The voting threshold controls the coverage precision trade off, enabling task specific optimization for different clinical requirements. Ultimately, on a multiclass hepatic vessel dataset, compared to MedSAM2 baselines, our method achieves an increase of 1.6 in mIoU and 1.9 in aIoU, along with a reduction of approximately 2.0 in HD95. Code will be available at https://github.com/AIGeeksGroup/SegTTA.
SGP-SAM: Self-Gated Prompting for Transferring 3D Segment Anything Models to Lesion Segmentation
Large segmentation foundation models such as the Segment Anything Model (SAM) have reshaped promptable segmentation in natural images, and recent efforts have extended these models to medical images and volumetric settings. However, directly transferring a 3D SAM-style model to lesion segmentation remains challenging due to (i) weak spatial representational capacity for small, irregular targets in intermediate features, and (ii) extreme foreground-background imbalance in 3D volumes.We propose SGP-SAM, a self-gated prompting framework for efficient and effective transfer to 3D lesion segmentation. Our key component, the Self-Gated Prompting Module (SGPM), performs conditional multi-scale spatial enhancement: a lightweight multi-channel gating unit predicts whether the current features require additional multi-scale fusion, and only then activates a Multi-Scale Feature Fusion Block to enrich spatial context. To further address small-lesion learning, we design a Zoom Loss that up-weights lesion-focused supervision by combining Dice and a voxel-balanced focal term.Experiments on MSD Liver Tumor and MSD Brain Tumor (enhancing tumor) show consistent gains over strong transfer baselines based on SAM-Med3D. On MSD Liver Tumor, SGP-SAM improves mDice by 7.3% over fine-tuning.
NTIRE 2026 Rip Current Detection and Segmentation (RipDetSeg) Challenge Report
This report presents the NTIRE 2026 Rip Current Detection and Segmentation (RipDetSeg) Challenge, which targets automatic rip current understanding in images. Rip currents are hazardous nearshore flows that cause many beach-related fatalities worldwide, yet remain difficult to identify because their visual appearance varies substantially across beaches, viewpoints, and sea states. To advance research on this safety-critical problem, the challenge builds on the RipVIS benchmark, evaluating both detection and segmentation. The dataset is diverse, sourced from more than countries, with camera orientations and diverse beach and sea conditions. This report describes the dataset, challenge protocol, evaluation methodology, final results, and summarizes the main insights from the submitted methods. The challenge attracted registered participants and produced valid test submissions across the two tasks. Final rankings are based on a composite score that combines , , , and . Most participant solutions relied on pretrained models, combined with strong augmentation and post-processing design. These results suggest that rip current understanding benefits strongly from the robust general-purpose vision models' progress, while leaving ample room for future methods tailored to their unique visual structure.
Adverse-to-the-eXtreme Panoptic Segmentation: URVIS 2026 Study and Benchmark
This paper presents the report of the URVIS 2026 challenge on adverse-to-extreme panoptic segmentation. As the first challenge of its kind, it attracted 17 registered participants and 47 submissions, with 4 teams reaching the final phase. The challenge is based on the MUSES dataset, a multi-sensor benchmark for panoptic segmentation in adverse-to-extreme weather, including RGB frame camera, LiDAR, radar, and event camera data. Weighted Panoptic Quality (wPQ) is designed and adopted as the official ranking metric for fair evaluation across weather conditions. In this report, we summarise the challenge setting and benchmark results, analyse the performance of the submitted methods, and discuss current progress and remaining challenges for robust multimodal panoptic segmentation. Link: https://urvis-workshop.github.io/challenge-Muses.html
Channel Attention-Guided Cross-Modal Knowledge Distillation for Referring Image Segmentation
Referring image segmentation (RIS) requires accurate segmentation of target regions in images according to language descriptions, which is a cross-modal task integrating vision and language. Existing RIS methods typically employ large-scale vision and language encoding models to improve performance, but their enormous parameter size severely restricts deployment in scenarios with limited computing resources. To solve this problem, this paper proposes a channel attention-guided cross-modal knowledge distillation method, which transfers the high-order fine-grained correlations between vision and language learned by the teacher network, as well as the correlations between semantic components represented by each channel, to the student network. Compared with the traditional pixel-wise relational distillation, this method not only enables the student to learn the knowledge of the teacher, but also retains part of its independent learning ability, alleviating the transfer of learning bias. Experimental results on two public datasets show that the proposed distillation method does not introduce additional parameters during inference and can achieve significant performance improvement for the student model.
TwinTrack: Post-hoc Multi-Rater Calibration for Medical Image Segmentation
Pancreatic ductal adenocarcinoma (PDAC) segmentation on contrast-enhanced CT is inherently ambiguous: inter-rater disagreement among experts reflects genuine uncertainty rather than annotation noise. Standard deep learning approaches assume a single ground truth, producing probabilistic outputs that can be poorly calibrated and difficult to interpret under such ambiguity. We present TwinTrack, a framework that addresses this gap through post-hoc calibration of ensemble segmentation probabilities to the empirical mean human response (MHR) -the fraction of expert annotators labeling a voxel as tumor. Calibrated probabilities are thus directly interpretable as the expected proportion of annotators assigning the tumor label, explicitly modeling inter-rater disagreement. The proposed post-hoc calibration procedure is simple and requires only a small multi-rater calibration set. It consistently improves calibration metrics over standard approaches when evaluated on the MICCAI 2025 CURVAS-PDACVI multi-rater benchmark.
SegMix:Shuffle-based Feedback Learning for Semantic Segmentation of Pathology Images
Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data requires significant workload demands from experienced pathologists, limiting the application of deep learning. To overcome this challenge, relaxing the label conditions to image-level classification labels allows for more data to be used and more scenarios to be enabled. One approach is to leverage Class Activation Map (CAM) to generate pseudo pixel-level annotations for semantic segmentation with only image-level labels. However, this method fails to thoroughly explore the essential characteristics of pathology images, thus identifying only small areas that are insufficient for pseudo masking. In this paper, we propose a novel shuffle-based feedback learning method inspired by curriculum learning to generate higher-quality pseudo-semantic segmentation masks. Specifically, we perform patch level shuffle of pathology images, with the model adaptively adjusting the shuffle strategy based on feedback from previous learning. Experimental results demonstrate that our proposed approach outperforms state-of-the-arts on three different datasets.
PixDLM: A Dual-Path Multimodal Language Model for UAV Reasoning Segmentation
Reasoning segmentation has recently expanded from ground-level scenes to remote-sensing imagery, yet UAV data poses distinct challenges, including oblique viewpoints, ultra-high resolutions, and extreme scale variations. To address these issues, we formally define the UAV Reasoning Segmentation task and organize its semantic requirements into three dimensions: Spatial, Attribute, and Scene-level reasoning. Based on this formulation, we construct DRSeg, a large-scale benchmark for UAV reasoning segmentation, containing 10k high-resolution aerial images paired with Chain-of-Thought QA supervision across all three reasoning types. As a benchmark companion, we introduce PixDLM, a simple yet effective pixel-level multimodal language model that serves as a unified baseline for this task. Experiments on DRSeg establish strong baseline results and highlight the unique challenges of UAV reasoning segmentation, providing a solid foundation for future research.
Perturbation-Regularized Open-Vocabulary Remote Sensing Segmentation with Unified Multi-Domain Evaluation
Open-vocabulary remote sensing image segmentation (OVRSIS) aims to segment text-specified categories beyond a fixed label space. Its key challenge is to maintain reliable pixel--text correspondence under substantial appearance variation in remote-sensing imagery. Existing methods often rely on specialized vision--language representations or complex adaptation mechanisms, yet still perform deterministic matching between fixed text prototypes and individual visual features. We instead formulate OVRSIS as a \emph{distributional pixel--text alignment} problem and propose \textbf{Pi-Seg}, a lightweight perturbation-based framework. Pi-Seg introduces learnable variations into textual prototypes and dense visual features before alignment. Segmentation supervision encourages perturbations that enlarge the target-to-distractor margin while suppressing harmful feature shifts. Pi-Seg consistently improves performance under the existing \textit{single-source} OVRSISBench protocols. To evaluate OVRSIS beyond source-specific training settings, we further introduce a unified \textit{multi-source} protocol and construct \textbf{GlobalRSOV95K}, containing approximately 95K densely annotated images and 35 semantic categories. Models are trained on this shared dataset and evaluated on an image-disjoint suite of 10 downstream datasets. The complete benchmark covers more than 170K images and 122 categories. Experiments under both single-source and multi-source protocols show that Pi-Seg improves cross-dataset transfer and generalizes effectively to practical geospatial segmentation tasks, while GlobalRSOV95K provides a common foundation for transferable OVRSIS research. \footnote{https://github.com/LiBingyu01/Pi-Seg}
CTSCAN: Evaluation Leakage in Chest CT Segmentation and a Reproducible Patient-Disjoint Benchmark
Reported chest CT segmentation performance can be strongly inflated when train and test partitions mix slices from the same study. We present CTSCAN, a reproducible multi-source chest CT benchmark and research stack designed to measure what survives under patient-disjoint evaluation. The current four-class artifact aggregates 89 cases from PleThora, MedSeg SIRM, and LongCIU, and we show that the original slice-PNG workflow induces near-complete case reuse across train, validation, and test. Using the playground environment, we run a multi-seed protocol sweep with the same FPN plus EfficientNet-B0 control configuration under slice-mixed and case-disjoint evaluation. Across 3 seeds and 12 epochs per seed, the slice-mixed protocol reaches 0.6665 foreground Dice and 0.5031 foreground IoU, whereas the case-disjoint protocol reaches 0.2066 Dice and 0.1181 IoU. Removing patient reuse therefore reduces foreground Dice by 0.4599 absolute (69.00% relative) and foreground IoU by 0.3850 absolute (76.52% relative). CTSCAN packages the corrected benchmark with deterministic split manifests, explicit weak-supervision controls, a scripted multi-seed protocol sweep, and reproducible figure generation, providing a reusable basis for patient-disjoint chest CT evaluation.
UA-Net: Uncertainty-Aware Network for TRISO Image Semantic Segmentation
Tristructural isotropic (TRISO)-coated particle fuels undergo dimensional changes and chemical reactions during high-temperature neutron irradiation. Post-irradiation materialography helps understand processes that impact fuel performance, such as coating integrity and fission product retention. Conventionally, experts manually evaluate features in thousands of cross sections of sub-mm-sized samples, which is tedious and subjective. In this work, we propose UA-Net, a deep learning framework that segments five characteristic regions of TRISO fuel micrographs and generates an uncertainty map for predictions. The model uses a multi-stage pretraining strategy, starting with general image representations learned from ImageNet, followed by fine-tuning on TRISO micrographs from various irradiation experiments and AGR-5/6/7 particle cross sections. A meta-model for uncertainty prediction is integrated to identify small defects in TRISO images. UA-Net was evaluated on a test set of 102 images, achieving mean Intersection over Union (mIoU) and mean Precision (mP) of 95.5% and 97.3%, respectively. The meta-model achieved a specificity of 91.8% and sensitivity of 93.5%, demonstrating strong performance in detecting misclassifications. The model was also applied to new TRISO images for qualitative evaluation, showing high accuracy in extracting layer regions.
SegWithU: Uncertainty as Perturbation Energy for Single-Forward-Pass Risk-Aware Medical Image Segmentation
Reliable uncertainty estimation is critical for medical image segmentation, where automated contours feed downstream quantification and clinical decision support. Many strong uncertainty methods require repeated inference, while efficient single-forward-pass alternatives often provide weaker failure ranking or rely on restrictive feature-space assumptions. We present , a post-hoc framework that augments a frozen pretrained segmentation backbone with a lightweight uncertainty head. SegWithU taps intermediate backbone features and models uncertainty as perturbation energy in a compact probe space using rank-1 posterior probes. It produces two voxel-wise uncertainty maps: a calibration-oriented map for probability tempering and a ranking-oriented map for error detection and selective prediction. Across ACDC, BraTS2024, and LiTS, SegWithU is the strongest and most consistent single-forward-pass baseline, achieving AUROC/AURC of , , and , respectively, while preserving segmentation quality. These results suggest that perturbation-based uncertainty modeling is an effective and practical route to reliability-aware medical segmentation. Source code is available at https://github.com/ProjectNeura/SegWithU.
Efficient Search of Implantable Adaptive Cells for Medical Image Segmentation
Purpose: Adaptive skip modules can improve medical image segmentation, but searching for them is computationally costly. Implantable Adaptive Cells (IACs) are compact NAS modules inserted into U-Net skip connections, reducing the search space compared with full-network NAS. However, the original IAC framework still requires a 200-epoch differentiable search for each backbone and dataset. Methods: We analyzed the temporal behavior of operations and edges within IAC cells during differentiable search on public medical image segmentation benchmarks. We found that operations selected in the final discrete cell typically emerge among the strongest candidates early in training, and their architecture parameters stabilize well before the final epoch. Based on this, we propose a Jensen--Shannon-divergence-based stability criterion that tracks per-edge operation-importance distributions and progressively prunes low-importance operations during search. The accelerated framework is called IAC-LTH. Results: Across four public benchmarks (ACDC, BraTS, KiTS, AMOS), several 2-D U-Net backbones, and a 2-D nnU-Net pipeline, IAC-LTH discovers IAC cells whose patient-level segmentation performance matches and sometimes slightly exceeds that of cells found by the original full-length search, while reducing wall-clock NAS cost by 3.7x to 16x across datasets and backbones. These results are consistent across architectures, benchmarks, and both non-augmented and augmented training settings, while preserving the gains of IAC-equipped U-Nets over strong attention-based and dense-skip baselines. Conclusion: Competitive IAC architectures can be identified from early-stabilizing operations without running the full search, making adaptive skip-module design more practical for medical image segmentation under realistic computational constraints.
From Boundaries to Semantics: Prompt-Guided Multi-Task Learning for Petrographic Thin-section Segmentation
Grain-edge segmentation (GES) and lithology semantic segmentation (LSS) are two pivotal tasks for quantifying rock fabric and composition. However, these two tasks are often treated separately, and the segmentation quality is implausible albeit expensive, time-consuming, and expert-annotated datasets have been used. Recently, foundation models, especially the Segment Anything Model (SAM), have demonstrated impressive robustness for boundary alignment. However, directly adapting SAM to joint GES and LSS is nontrivial due to 1) severe domain gap induced by extinction-dependent color variations and ultra-fine grain boundaries, and 2) lacking novel modules for joint learning on multi-angle petrographic image stacks. In this paper, we propose Petro-SAM, a novel two-stage, multi-task framework that can achieve high-quality joint GES and LSS on petrographic images. Specifically, based on SAM, we introduce a Merge Block to integrate seven polarized views, effectively solving the extinction issue. Moreover, we introduce multi-scale feature fusion and color-entropy priors to refine the detection.
Data Synthesis Improves 3D Myotube Instance Segmentation
Myotubes are multinucleated muscle fibers serving as key model systems for studying muscle physiology, disease mechanisms, and drug responses. Mechanistic studies and drug screening thereby rely on quantitative morphological readouts such as diameter, length, and branching degree, which in turn require precise three-dimensional instance segmentation. Yet established pretrained biomedical segmentation models fail to generalize to this domain due to the absence of large annotated myotube datasets. We introduce a geometry-driven synthesis pipeline that models individual myotubes via polynomial centerlines, locally varying radii, branching structures, and ellipsoidal end caps derived from real microscopy observations. Synthetic volumes are rendered with realistic noise, optical artifacts, and CycleGAN-based Domain Adaptation (DA). A compact 3D U-Net with self-supervised encoder pretraining, trained exclusively on synthetic data, achieves a mean IPQ of 0.22 on real data, significantly outperforming three established zero-shot segmentation models, demonstrating that biophysics-driven synthesis enables effective instance segmentation in annotation-scarce biomedical domains.
ProtoFlow: Mitigating Forgetting in Class-Incremental Remote Sensing Segmentation via Low-Curvature Prototype Flow
Remote sensing segmentation in real deployment is inherently continual: new semantic categories emerge, and acquisition conditions shift across seasons, cities, and sensors. Despite recent progress, many incremental approaches still treat training steps as isolated updates, which leaves representation drift and forgetting insufficiently controlled. We present ProtoFlow, a time-aware prototype dynamics framework that models class prototypes as trajectories and learns their evolution with an explicit temporal vector field. By jointly enforcing low-curvature motion and inter-class separation, ProtoFlow stabilizes prototype geometry throughout incremental learning. Experiments on standard class- and domain-incremental remote sensing benchmarks show consistent gains over strong baselines, including up to 1.5-2.0 points improvement in mIoUall, together with reduced forgetting. These results suggest that explicitly modeling temporal prototype evolution is a practical and interpretable strategy for robust continual remote sensing segmentation. Open-source code:https://github.com/dudududke/protoflow.
PRUE: A Practical Recipe for Field Boundary Segmentation at Scale
Large-scale maps of field boundaries are essential for agricultural monitoring tasks. Existing deep learning approaches for satellite-based field mapping are sensitive to illumination, spatial scale, and changes in geographic location. We conduct the first systematic evaluation of segmentation and geospatial foundation models (GFMs) for global field boundary delineation using the Fields of The World (FTW) benchmark. We evaluate 18 models under unified experimental settings, showing that a U-Net semantic segmentation model outperforms instance-based and GFM alternatives on a suite of performance and deployment metrics. We propose a new segmentation approach that combines a U-Net backbone, composite loss functions, and targeted data augmentations to enhance performance and robustness under real-world conditions. Our model achieves a 76% IoU and 47% object-F1 on FTW, an increase of 6% and 9% over the previous baseline. Our approach provides a practical framework for reliable, scalable, and reproducible field boundary delineation across model design, training, and inference. We release all models and model-derived field boundary datasets for five countries.
LoGSAM: Parameter-Efficient Cross-Modal Grounding for MRI Segmentation
Precise localization and delineation of brain tumors using magnetic resonance imaging (MRI) are essential for planning therapy and guiding surgical decisions. To address this, we propose LoGSAM, a parameter-efficient, detection-driven framework that transforms radiologist dictation into text prompts for foundation-model-based localization and segmentation. Radiologist speech is first transcribed and translated using a pretrained Whisper ASR model, followed by negation-aware clinical NLP to extract tumor-specific textual prompts. These prompts guide text-conditioned tumor localization via a LoRA-adapted vision-language detection model, Grounding DINO (GDINO). The predicted bounding boxes are used as prompts for MedSAM to generate pixel-level tumor masks without any additional fine-tuning. On BRISC 2025, LoGSAM attains a Dice score of 80.32%, reaching 98.6% of a fully fine-tuned GDINO + MedSAM baseline while training fewer than 5% of its parameters, indicating a favorable accuracy/parameter trade-off. In addition, we evaluate the full pipeline using German dictations from a board-certified radiologist on unseen MRI scans, achieving 91.7% case-level class-extraction accuracy. These results highlight the feasibility of constructing a modular speech-to-segmentation pipeline from pretrained foundation models with minimal parameter updates.
GP-VMSMA: Benchmarking General-Purpose Vision Models and Specialized Architectures for 2D Medical Image Segmentation
Medical image segmentation (MIS) is a fundamental component of computer-assisted diagnosis and clinical decision support. Over the past decade, numerous architectures specifically tailored to medical imaging have emerged to address domain-specific challenges such as low contrast, small anatomical structures, and limited annotated data. In parallel, rapid progress in computer vision has produced highly capable general-purpose vision models (GP-VMs) originally designed for natural images. Despite their strong performance on standard vision benchmarks, their effectiveness for MIS remains insufficiently understood. In this controlled empirical study, we examine whether specialized medical segmentation architectures (SMAs) provide systematic advantages over modern GP-VMs for 2D MIS. We compare eleven SMAs and GP-VMs using a unified training and evaluation protocol across three heterogeneous datasets, each covering different 2D imaging modalities, class structures, and data characteristics. Beyond segmentation performance, we employ linear mixed-effects models (LMMs) for statistical assessment and qualitative Grad-CAM visualizations to investigate explainability (XAI)-related model behavior. Our results imply that, for the analyzed settings, GP-VMs achieve performance comparable to that of specialized MIS models. Moreover, XAI analyses indicate that GP-VMs are capable of identifying clinically relevant structures despite the absence of explicit domain-specific architectural priors. These findings suggest that GP-VMs can represent a viable alternative to domain-specific methods for 2D MIS, highlighting the importance of informed model selection. All code and resources are available at GitHub.
Bi-CamoDiffusion: A Boundary-informed Diffusion Approach for Camouflaged Object Detection
Bi-CamoDiffusion is introduced, an evolution of the CamoDiffusion framework for camouflaged object detection. It integrates edge priors into early-stage embeddings via a parameter-free injection process, enhancing boundary sharpness and preventing structural ambiguity. An optimization objective that unifies spatial accuracy, structural constraints, and uncertainty supervision is also proposed, allowing the model to capture of both the object's global context and its intricate boundary transitions. Evaluations across the CAMO, COD10K, and NC4K datasets show that Bi-CamoDiffusion surpasses the baseline, delivering sharper delineation of thin structures and protrusions while also minimizing false positives. The model consistently outperforms existing state-of-the-art methods across all evaluated metrics, including , , , and , demonstrating a more precise object-background separation and sharper boundary recovery. Code available at: https://github.com/plsuarez/Bi-CamoDiffusion
StructSAM: Structure- and Spectrum-Preserving Token Merging for Segment Anything Models
Recent token merging techniques for Vision Transformers (ViTs) provide substantial speedups by reducing the number of tokens processed by self-attention, often without retraining. However, their direct application to the Segment Anything Model (SAM) family is nontrivial: SAM's image encoder mixes windowed and global attention, and its mask decoder relies on dense, prompt-conditioned features for precise boundary prediction. We systematically evaluate representative token-merging methods on SAM and Medical SAM in a strict off-the-shelf setting, and find that existing destination-selection heuristics can erode boundaries and leak prompt information as merge rates increase. We propose \textbf{StructSAM}, a resolution-preserving merge-unmerge framework tailored to SAM. StructSAM computes a lightweight token-energy score from first-order feature gradients, uses grid-based flatness screening to protect boundary and prompt regions, and merges tokens within flat areas toward low-energy destinations with explicit token recovery. We further provide a spectral graph coarsening view showing that score-guided merging yields bounded Laplacian spectral distortion compared to random or window-restricted baselines. Across eight natural and medical benchmarks, StructSAM reduces encoder FLOPs by 25-30% (up to 40%+ with prompt-aware merging) with minor drops in mIoU/Dice, consistently outperforming ToMe, PiToMe, ToMeSD, VidToMe, and ALGM at the same compute.
LAW & ORDER: Adaptive Spatial Weighting for Medical Diffusion and Segmentation
Medical image analysis depends on accurate segmentation and controllable synthesis, but both tasks face severe spatial imbalance: lesions occupy small regions against large backgrounds. We study adaptive spatial weighting as a task-level design principle and instantiate it in two adapters. LAW learns per-pixel loss weights for mask-conditioned diffusion by modulating a ratio prior with a feature-dependent delta map, with normalization, clamping, and Dice regularization for stability. ORDER improves lightweight segmentation by adding selective bidirectional skip attention with stage-wise confidence gating. On held-out diffusion test sets, LAW lowers FID from 158.130.15 to 108.430.71 on Polyps, from 144.130.31 to 89.510.96 on KiTS19, and from 139.220.38 to 112.580.68 on BRISC, while improving held-out mask-recovery Dice from 0.6810.013 to 0.8250.003 on Polyps. When the resulting images are added to nnUNet training, downstream Polyps mDice rises from 71.70.4 to 74.10.8. On the cleaned Polyps segmentation protocol, the reported ORDER configuration reaches 76.31.9 mDice and 67.22.0 mIoU at 42K parameters and 0.11 GFLOPs, versus 70.31.5 mDice and 59.91.7 mIoU for matched MK-UNet. On BRISC under the same training recipe, ORDER reaches 77.40.8 mDice and 68.10.7 mIoU. These results position adaptive spatial weighting as a practical design idea for both medical diffusion and efficient segmentation.