Wireless Foundation Models

Wireless foundation models are rapidly emerging as a key enabler of AI-native communication systems, yet a fundamental question remains unanswered: how large should these models be? We present a principled, physics-grounded answer, showing that the intrinsic dimensionality (dNL, the nonlinear manifold dimension of the channel) acts as the fundamental bottleneck, defining the scaling ceiling once a data-sufficient regime is reached. This dimensionality is not a design choice but a physical constraint: Maxwell's equations, finite scatterers, and antenna aperture inherently constrain wireless propagation environments to a limited number of degrees of freedom -- spanning 5-35 across both real-world OTA measurements and 3GPP-standardized channel models we evaluate -- orders of magnitude below the ~1,000-dimensional semantic space of language. As a consequence, we propose a scaling framework for wireless AI: taking NTN satellite channels as a representative case (dNL ~= 14), scaling gains diminish rapidly beyond ~30 million parameters, entering a stochastic asymptote above 70M where a further 1.6x increase (96M->150M) yields only 0.52 dB. Beyond this ceiling, inference-time adaptation via pilot-aided test-time training (TTT) is far more effective: a compact 12M-parameter model surpasses a static 96M model by 9.9 dB (NMSE, SNR = 20 dB) / 7.6 dB (MCM, SNR = 10 dB) at one-eighth the parameters. With dNL distributions validated across real-world indoor massive MIMO measurements, our scaling laws and TTT gains are demonstrated through NTN satellite simulations, reframing wireless AI design: channel geometry -- not model size -- fundamentally governs the scaling laws of physical-layer wireless AI.

Foundation models (FMs) have shown great promise in medical imaging, but most FMs are trained on unimodal data within isolated domains, such as brain MRI alone. Human aging and disease arise through coordinated biological processes across organs, therefore motivating multimodal FMs that learn whole-body representations. A key challenge, however, is that real-world multimodal biomedical data are often missing not at random, which can reduce power, limit generalizability, and introduce bias. We propose Pan-FM, a pan-organ foundation model pre-trained on imaging from seven organs (Brain, Heart, Adipose, Liver, Kidney, Spleen, and Pancreas) under realistic missing-organ scenarios. Pan-FM uses a unified backbone that handles organ missingness during both training and inference, and is pre-trained with masking-based self-distillation. We find that naive multimodal pre-training leads to dominant-organ shortcut learning bias, with the model over-relying on dominant organs such as adipose and heart. To address this, we introduce Saliency-Guided Masking (SGM), which uses the model attention distribution to adaptively mask dominant organs during pre-training, thus encouraging more balanced cross-organ, whole-body learning. Notably, SGM introduces negligible computational overhead and can be seamlessly integrated into existing self-supervised learning frameworks to improve multi-organ representation learning. On the UK Biobank, Pan-FM achieves stronger prediction across 13 disease categories and 14 single disease entities than single-organ and multi-organ baselines, with improved robustness under missing-organ settings. Pan-FM serves as a scalable solution to realistic modality-missingness in multimodal learning in system neuroscience and as a step toward more generalizable whole-body FMs.

Foundation models (FMs) are increasingly deployed in open-world settings where distribution shift is the rule rather than the exception. The out-of-distribution (OOD) phenomena they face -- knowledge boundaries, capability ceilings, compositional shifts, and open-ended task variation -- differ in kind from the settings that have shaped prior OOD research, and are further complicated because the pretraining and post-training distributions of modern FMs are often only partially observed. Our position is that OOD for foundation models is a structurally distinct problem that cannot be solved within the prevailing model-centric paradigm, and that agentic systems constitute the missing paradigm required to address it. We defend this claim through four steps. First, we give a stage-aware formalization of OOD that accommodates partially observed multi-stage training distributions. Second, we prove a parameter coverage ceiling: there exist practically relevant inputs that no model-centric method (training-time or test-time) can handle within tolerance $\varepsilon$, for reasons intrinsic to parameter-based representation. Third, we characterize agentic OOD systems by four structural properties -- perception, strategy selection, external action, and closed-loop verification -- and show that they strictly extend the reachable set beyond the ceiling. Fourth, we respond to seven counterarguments, conceding two, and outline a research agenda. We do not claim that agentic methods subsume model-centric ones; we argue that the two are complementary, and that progress on FM-OOD requires explicit recognition of the agentic paradigm as a first-class research direction.

We propose an architecture that augments the Flux Neural Operator (Flux NO), which combines the classical finite volume method (FVM) with neural operators, with ViT-based context injection. Our model is formulated as a hypernetwork: it extracts solution dynamics over a finite temporal window, encodes them with a recurrent Vision Transformer, and generates the parameters of a context-conditioned neural operator. This enables the model to infer and solve conservation laws without explicit access to the governing equation or PDE coefficients. Experimentally, we show that the proposed method preserves the robustness, generalization ability, and long-time prediction advantages of Flux NO over standard neural operators, while delivering reliable numerical solutions across a broad range of conservative systems, including previously unseen fluxes. Our code is available at https://github.com/xx257xx/CONTEXT_FLUX_NO.

Wildfire burned-area mapping is essential for damage assessment, emissions modeling, and understanding fire-climate interactions across diverse ecological regions. Recent geospatial foundation models provide strong general-purpose representations for satellite imagery, yet there is still no clear understanding of how to efficiently adapt these models for downstream Earth observation tasks, particularly under geographic and temporal domain shift. This study evaluates three state-of-the-art Geospatial Foundation Models (GFMs) - Terramind, DINOv3, and Prithvi-v2 - for burned-area mapping across the United States and Canada using Sentinel-2 data. Leveraging 3,820 wildfire events from 2017-2023, we conduct spatial and temporal generalization tests across diverse biomes. We systematically compare full fine-tuning, decoder-only fine-tuning, and Low-Rank Adaptation (LoRA) for adapting each model. Across all experiments, LoRA provides the strongest cross-domain generalization while updating less than 1% of parameters, demonstrating a favorable trade-off between accuracy and efficiency. Prithvi-v2 with LoRA achieves the highest overall accuracy and the largest improvement compared to full fine-tuning. These findings indicate that geospatial foundation models, when adapted using lightweight parameter-efficient methods such as LoRA, offer a robust and scalable solution for large-scale burned-area mapping. Code is available at https://github.com/alishibli97/wildfire-lora-gfm.

Inductive Logic Programming (ILP) learns interpretable logical rules from data. Existing methods are transductive: their learned parameters are bound to specific predicates and require retraining for each new task. We introduce Neural Rule Inducer (NRI), a pretrained model for zero-shot rule induction. Rather than encoding literal identities, NRI represents literals using domain-agnostic statistical properties such as class-conditional rates, entropy, and co-occurrence, which generalize across variable identities and counts without retraining. The model consists of a statistical encoder and a parallel slot-based decoder. Parallel decoding preserves the permutation invariance of logical disjunction; an autoregressive decoder would instead impose an arbitrary clause order. Product T-norm relaxation makes rule execution differentiable, allowing end-to-end training on prediction accuracy alone. We evaluate NRI on rule recovery, robustness to label noise and spurious correlations, and zero-shot transfer to real-world benchmarks, and we believe this work opens up the possibility of foundation models for symbolic reasoning. Code and the reference checkpoint are available at https://github.com/phuayj/neural-rule-inducer.

Unlike vision and language domains, graph learning lacks a shared input space, as input features differ across graph datasets not only in semantics, but also in value ranges and dimensionality. This misalignment prevents graph models from generalizing across datasets, limiting their use as foundation models. In this work, we propose ALL-IN, a simple and theoretically grounded method that enables transferability across datasets with different input features. Our approach projects node features into a shared random space and constructs representations via covariance-based statistics, thus eliminating dependence on the original feature space. We show that the computed node-covariance operators and the resulting node representations are invariant in distribution to permutations of the input features. We further demonstrate that the expected operator exhibits invariance to general orthogonal transformations of the input features. Empirically, ALL-IN achieves strong performance across diverse node- and graph-level tasks on unseen datasets with new input features, without requiring architecture changes or retraining. These results point to a promising direction for input-agnostic, transferable graph models.

Mechanical equipment forms the critical backbone of modern industrial production, yet domain shift severely limits the generalization of deep learning based fault diagnosis models across different equipment and operating conditions.Inspired by the success of foundation models in achieving zero-shotgeneralization, we propose YOTOnet (You Only Train Once), a novel architecture specifically designed for cross-domain fault diagnosis in mechanical equipment.YOTOnet comprises three core components: (1) a physics-aware Invariant Feature Distiller that extracts domain-agnostic representations using multi-scale dilated convolutions and FFT-based time-frequency fusion,(2) Domain-Conditioned Sparse Experts (DC-MoE) that adaptively route inputs to specialized processors via learned gating without external meta-data, and (3) a dual-head classification system with auxiliary supervision.Extensive validation on five public bearing datasets (CWRU, MFPT, XJTU,OTTAWA, HUST) through 30 cross-dataset protocols demonstrates the superiority of YOTOnet compared with other state-of-the-art methods. Critically, we observe a clear scaling effect-average test F1 improves from 0.5339(1 training dataset) to 0.705 (4 datasets), with a clear gain when moving from 3 to 4 datasets. These findings provide empirical evidence that foundation model principles can enable robust, train-once deployment for industrial fault diagnosis.

Medical foundation models pre-trained on large-scale datasets have shown powerful versatile performance. However, when adapting medical foundation models for specific medical scenarios, it remains the inevitable challenge due to the gap induced by the discrepancy between pre-training and downstream tasks, the real-world computation, and speed constraints. Relevant techniques that probably handle this challenge more or less suffer from some intrinsic limitations. For example, knowledge distillation (KD) assumes that teacher and student models share the same task, training strategy, and model structure family, while prevalent parameter-efficient fine-tuning (PEFT) fails to achieve personalized and lightweight deployment. Even the combination of PEFT and KD still struggles to resolve model structures and training strategies inconsistencies between teacher and student models, leading to inefficient knowledge transfer. In this study, we propose a novel framework called Deep Reprogramming Distillation (DRD) to combat the general adaptation challenge. Specifically, DRD introduces the novel reprogramming module that on the one side overcomes the domain and task discrepancy between pretraining and downstream scenarios, and on the other side builds the student-friendly efficient distillation from foundation models to lightweight downstream models. Furthermore, to mitigate variability under different training conditions, we design a centered kernel alignment (CKA) distillation method to promote robust knowledge transfer. Empirical results show that DRD surpasses previous PEFT and KD methods across 18 medical downstream tasks under different foundation models, covering various scenarios including 2D/3D classification and 2D/3D segmentation.

Audio-Visual Intelligence (AVI) has emerged as a central frontier in artificial intelligence, bridging auditory and visual modalities to enable machines that can perceive, generate, and interact in the multimodal real world. In the era of large foundation models, joint modeling of audio and vision has become increasingly crucial, i.e., not only for understanding but also for controllable generation and reasoning across dynamic, temporally grounded signals. Recent advances, such as Meta MovieGen and Google Veo-3, highlight the growing industrial and academic focus on unified audio-vision architectures that learn from massive multimodal data. However, despite rapid progress, the literature remains fragmented, spanning diverse tasks, inconsistent taxonomies, and heterogeneous evaluation practices that impede systematic comparison and knowledge integration. This survey provides the first comprehensive review of AVI through the lens of large foundation models. We establish a unified taxonomy covering the broad landscape of AVI tasks, ranging from understanding (e.g., speech recognition, sound localization) to generation (e.g., audio-driven video synthesis, video-to-audio) and interaction (e.g., dialogue, embodied, or agentic interfaces). We synthesize methodological foundations, including modality tokenization, cross-modal fusion, autoregressive and diffusion-based generation, large-scale pretraining, instruction alignment, and preference optimization. Furthermore, we curate representative datasets, benchmarks, and evaluation metrics, offering a structured comparison across task families and identifying open challenges in synchronization, spatial reasoning, controllability, and safety. By consolidating this rapidly expanding field into a coherent framework, this survey aims to serve as a foundational reference for future research on large-scale AVI.

Semantic segmentation provides pixel-level scene understanding essential for autonomous driving and fine-grained perception tasks. However, training segmentation models requires costly, labor-intensive annotations on real-world datasets. Unsupervised Domain Adaptation (UDA) addresses this by training models on labeled synthetic data and adapting them to unlabeled real images. While conceptually simple, adaptation is challenging due to the domain gap, i.e., differences in visual appearance and scene structure between synthetic and real data. Prior approaches bridge this gap through pixel-level mixing or feature-level contrastive learning. Yet, these techniques suffer from two major limitations: (1) reliance on high-confidence pseudo-labels restricts learning to a subset of the target domain, and (2) prototype-based contrastive methods initialize class prototypes from source-trained models, yielding biased and unstable anchors during adaptation. To address these issues, we propose a dual-foundation UDA framework that leverages two complementary foundation models. First, we employ the Segment Anything Model (SAM) with superpixel-guided prompting to enable learning from a broader range of target pixels beyond high-confidence predictions. Second, we incorporate DINOv3 to construct stable, domain-invariant class prototypes through its robust representation learning. Our method achieves consistent improvements of +1.3% and +1.4% mIoU over strong UDA baselines on GTA-to-Cityscapes and SYNTHIA-to-Cityscapes, respectively.

Automatic modulation classification (AMC) in real-world deployments demands robustness to distribution shifts arising from hardware impairments, unseen propagation environments, and recording conditions never encountered during training. Although wireless foundation models offer a promising starting point for robust RF representation learning, an important open question is how to adapt them efficiently to out-of-distribution (OOD) downstream tasks without overwriting the structure learned during large-scale pre-training. In this paper, we investigate prompt-based adaptation as a general mechanism for OOD transfer in wireless foundation models. We propose RFPrompt, a parameter-efficient framework that introduces learnable deep prompt tokens while keeping the pretrained backbone frozen, enabling task-specific adaptation with minimal trainable parameters. We instantiate and evaluate this approach on the Large Wireless Model (LWM), a mixture-of-experts wireless foundation model, and study its behavior under both standard and OOD modulation-classification settings. Results show that prompt-based adaptation consistently improves robustness under distribution shift and limited supervision, particularly on real-world over-the-air IQ data, while preserving strong parameter efficiency. These findings suggest that prompt learning is a practical and effective strategy for adapting wireless foundation models to challenging downstream RF environments.

This paper introduces the ensemble directional Kalman filter (EnDKF), an ensemble-based Kalman filtering approach for pose tracking that jointly estimates an object's position and attitude using ideas from directional statistics. The EnDKF integrates a unit-quaternion attitude representation to move beyond canonical Kalman filter mean and covariance assumptions that poorly capture directional uncertainty. Experiments on a synthetic constant-velocity constant-angular-velocity system and a digital-twin head-tracking scenario using the FoundationPose algorithm demonstrate a significant reduction in error as opposed to merely using measurements.

We present an experimental study of energy-to-solution (ETS) of hybrid quantum-classical applications, enabled by direct instrumentation of power consumption of a Forte Enterprise trapped-ion quantum processor. We apply this methodology to a hybrid quantum-classical pipeline for quantum fine-tuning of foundational AI models, and validate the approach end-to-end on quantum hardware. Despite noise and limited qubit counts, the resulting models achieve accuracy competitive with and exceeding classical baselines such as logistic regression and support vector classifiers. Our results show that QPU energy consumption scales approximately linearly with qubit number for shallow circuits, while classical simulation exhibits exponential scaling, indicating a break-even for ETS around 34 qubits. The classification error improvement of the best quantum fine-tuned model over the best classical fine-tuned model considered in this study is around 24%. We further contextualize these findings with comparisons to tensor network methods. This work establishes energy-to-solution as a measurable and scalable metric for evaluating quantum applications and provides experimental evidence of favorable energy-accuracy trade-offs.

Sleep foundation models have recently demonstrated strong performance on in-domain polysomnography tasks, including sleep staging, apnea detection, and disease risk prediction. In this work, we investigate whether sleep biosignals can serve as an effective pretraining distribution for learning representations that transfer beyond sleep to adjacent domains. Following sleep foundation models, we perform sleep-only multimodal contrastive pretraining (with a leave-one-out objective) and evaluate transfer to non-sleep EEG and ECG, two well-benchmarked biosignal modalities with heterogeneous datasets and clinically meaningful downstream tasks. Across eight downstream tasks spanning multiple EEG and ECG datasets, sleep pretraining consistently improves performance relative to training from scratch. Moreover, on several tasks, we achieve performance competitive with or surpassing prior specialized state-of-the-art and foundation models.

Emerging multi-modal world models attempt to jointly generate videos across diverse modalities (e.g., RGB, depth, and mask), yet they fail to fully exploit the rich priors of existing foundation models. We propose $M^2$-REPA, the first representation alignment method tailored for multi-modal video generation. Our key insight is that foundation models trained on different modality spaces naturally capture distinct domain-specific priors, acting as complementary "experts." Specifically, we first decouple modality-specific features from the diffusion model's intermediate representations, then align each with its corresponding expert foundation model. To this end, we design two synergistic objectives: a multi-modal representation alignment loss that enforces feature-to-expert matching, and a modality-specific decoupling regularization that encourages complementarity across different modalities. This design enables joint optimization, fully exploiting priors from multiple foundation models. Extensive experiments demonstrate that our method significantly outperforms baselines in visual quality and long-term consistency.

Wireless foundation models (WFMs) have emerged as a promising paradigm for unified channel state information (CSI) acquisition across diverse tasks in sixth-generation (6G) networks. Although WFMs significantly outperform task-specific small models, their zero-shot cross-scenario generalization still remains limited for real-world applications. Existing positional embeddings, the sole interface through which self-attention perceives the temporal-frequency-antenna 3D physical coordinates of CSI, fail to capture the highly dynamic and axis-dependent coherence inherent in wireless channels. This paper proposes Adaptive 3D-RoPE, a channel-driven 3D rotary positional embedding framework for WFMs to dynamically align the 3D positional embeddings with the instantaneous coherence state of heterogeneous CSI. The design proceeds in three stages: first, an axis-wise learnable rotary prior independently preserves the temporal, frequency, and antenna coordinate structures; second, a feature-guided rotary modulation module maps the feature-wise standard deviation of visible CSI tokens to compact, sample-adaptive scales; third, identical coordinate offsets induce dynamically adjusted query-key interactions tailored to the instantaneous channel state. Extensive experiments on both simulated and measured datasets validate the effectiveness of Adaptive 3D-RoPE across three complementary dimensions. It reduces NMSE by 10.14, 6.25, and 4.61 dB relative to baselines under antenna, temporal, and frequency scaling, respectively. It transfers effectively to real-world measured CSI and remains robust under imperfect CSI. Finally, it transfers to the independently designed LWM backbone and beam-prediction task, improving zero-shot Top-1 accuracy by 8.03 percentage points.

Deep learning in \emph{de novo} protein design has achieved atomic-level fidelity. However, existing models remain largely non-deliberative: they directly synthesize molecular geometries without explicitly reasoning about which residues or interactions are functionally essential. As a result, design decisions are entangled with continuous sampling dynamics, limiting interpretability, controllability, and systematic reuse of biochemical knowledge. We introduce \textbf{Proteo-R1}, a reasoning-guided protein design framework that explicitly decouples \emph{molecular understanding} from \emph{geometric generation}. Proteo-R1 adopts a dual-expert architecture in which a multimodal large language model (MLLM) serves as an \emph{understanding expert}, analyzing protein sequences, structures, and textual context to identify key functional residues that govern binding and specificity. These residue-level decisions are then passed as hard constraints to a separate diffusion-based \emph{generation expert}, which performs conditional co-design while respecting the fixed interaction anchors. This factorization mirrors how human experts approach molecular engineering: first, reasoning about critical interactions, then optimizing geometry subject to those constraints. By operationalizing reasoning as explicit residue-level commitments rather than latent textual guidance, Proteo-R1 achieves stable, interpretable, and modular integration of LLM reasoning with state-of-the-art geometric generative models. Code, data, and demos are available at https://smiles724.github.io/r1/.

Foundation models are deep neural networks (such as GPT-5, Gemini3, and Opus4) trained on large datasets that can perform diverse downstream tasks -- text and code generation, question answering, summarization, image classification, and so on. The philosophy of foundation models is to put effort into a single, large (${\sim}10^{12}$-parameter) general-purpose model that can be adapted to many downstream tasks with no or minimal additional training. We argue that the rise of foundation models presents an opportunity for hardware engineers: in contrast to when different models were used for different tasks, it now makes sense to build special-purpose, fixed hardware implementations of neural networks, manufactured and released at the roughly 1-year cadence of major new foundation-model versions. Beyond conventional digital-electronic inference hardware with read-only weight memory, we advocate a more radical re-thinking: hardware in which the neural network is realized directly at the level of the physical design and operates via the hardware's natural physical dynamics -- \textit{Physical Foundation Models} (PFMs). PFMs could enable orders-of-magnitude advantages in energy efficiency, speed, and parameter density. For ${\sim}10^{12}$-parameter models, this would both reduce the high energy burden of AI in datacenters and enable AI in edge devices that today are power-constrained to far smaller models. PFMs could also enable inference hardware for models much larger than current ones: $10^{15}$- or even $10^{18}$-parameter PFMs seem plausible by some measures. We present back-of-the-envelope calculations illustrating PFM scaling using an optical example -- a 3D nanostructured glass medium -- and discuss prospects in nanoelectronics and other physical platforms. We conclude with the major research challenges that must be resolved for trillion-parameter PFMs and beyond to become reality.

Agentic large language model systems have demonstrated strong capabilities. However, their reliance on language as the universal interface fundamentally limits their applicability to many real-world problems, especially in scientific domains where domain-specific foundation models have been developed to address specialized tasks beyond natural language. In this work, we introduce Eywa, a heterogeneous agentic framework designed to extend language-centric systems to a broader class of scientific foundation models. The key idea of Eywa is to augment domain-specific foundation models with a language-model-based reasoning interface, enabling language models to guide inference over non-linguistic data modalities. This design allows predictive foundation models, which are typically optimized for specialized data and tasks, to participate in higher-level reasoning and decision-making processes within agentic systems. Eywa can serve as a drop-in replacement for a single-agent pipeline (EywaAgent) or be integrated into existing multi-agent systems by replacing traditional agents with specialized agents (EywaMAS). We further investigate a planning-based orchestration framework in which a planner dynamically coordinates traditional agents and Eywa agents to solve complex tasks across heterogeneous data modalities (EywaOrchestra). We evaluate Eywa across a diverse set of scientific domains spanning physical, life, and social sciences. Experimental results demonstrate that Eywa improves performance on tasks involving structured and domain-specific data, while reducing reliance on language-based reasoning through effective collaboration with specialized foundation models.

Training stable biological foundation models requires rethinking attention mechanisms: we find that using sigmoid attention as a drop in replacement for softmax attention a) produces better learned representations: on six diverse single-cell datasets, sigmoid achieves 25% higher cell-type separation, better cell-type cohesion metrics, and lower validation loss, b) faster training, models with sigmoid attention train up to 10% faster than their softmax counterparts, and c) more stable training by eliminating inherent sources of instability in softmax attention. We establish that sigmoid attention has globally bounded derivatives ($\leq 0.25$) as opposed to softmax, and a diagonal Jacobian structure in contrast with softmax's dense coupling, which together help alleviate training instabilities. In stress tests on 160M-parameter bidirectional attention models trained without gradient clipping on 8K-token sequences, softmax diverges catastrophically, with gradients exploding by four orders of magnitude, while sigmoid remains stable. Finally, we implement and open-source TritonSigmoid, an efficient GPU kernel that achieves 515 TFLOPS on H100 GPUs, outperforming both FlashAttention-2 and FlashSigmoid, with native padding support, which is essential for biological sequences. Our results establish sigmoid attention as both theoretically grounded and empirically superior for biological foundation models. Code is available at https://github.com/MSDLLCpapers/triton-sigmoid

Recent advances in 4D content generation have attracted increasing attention, yet creating high-quality animated 3D models remains challenging due to the complexity of modeling spatio-temporal distributions and the scarcity of 4D training data. We present AnimateAnyMesh++, a feed-forward framework for text-driven animation of arbitrary 3D meshes with substantial upgrades in data, architecture, and generative capability. First, we expand the DyMesh-XL dataset by mining dynamic content from Objaverse-XL, increasing the number of unique identities from 60K to 300K and substantially broadening category and motion diversity. Second, we redesign DyMeshVAE-Flex with power-law topology-aware attention and vertex-normal enhanced features, which significantly improves trajectory reconstruction, local geometry preservation, and mitigates trajectory-sticking artifacts. Third, we introduce architectural changes to both DyMeshVAE-Flex and the rectified-flow (RF) generator to support variable-length sequence training and generation, enabling longer animations while preserving reconstruction fidelity. Extensive experiments demonstrate that AnimateAnyMesh++ generates semantically accurate and temporally coherent mesh animations within seconds, surpassing prior approaches in quality and efficiency. The enlarged DyMesh-XL, the upgraded DyMeshVAE-Flex, and variable-length RF together deliver consistent gains across benchmarks and in-the-wild meshes. We will release code, models, and the expanded DyMesh-XL upon acceptance of this manuscript to facilitate research in 4D content creation.

Mobile agent systems are emerging as a key paradigm for enabling intelligent applications on edge devices and in AIoT ecosystems. However, their scalability is fundamentally constrained by limited on-device computation and fragmented intelligence across devices. In this work, we propose a unified research agenda for scaling mobile agent systems along two complementary dimensions: (1) improving capability density of individual agents through compact foundation model design and compression, and (2) enabling collective intelligence via communication-rich multi-agent collaboration. Building on recent model and infrastructure advances, this vision aims to transform isolated mobile agents into a distributed intelligent system that is efficient and scalable.

Foundation models of brain activity promise a new frontier for in silico neuroscience by emulating neural responses to complex stimuli across tasks and modalities. A natural next step is to ask whether these models can also be used in reverse. Can we recover a stimulus or its properties from synthetic brain activity? We study this question in a proof-of-concept setting using TRIBEv2. We pair the brain emulator with large language models (LLMs) that generate news headlines from linguistic parameters such as valence, arousal, and dominance. We then use simulation-based inference to learn a probabilistic mapping from brain maps to latent stimulus parameters. Our results show that these parameters can be recovered from predicted brain maps, validating the quality of neural encodings. They also show that LLMs can serve as controllable stimulus generators for simulated experiments. Together, these findings provide a step toward decoding and inverse design with foundation brain models.

Deploying machine learning models across diverse well portfolios requires generalisation to wells with design parameters outside the training distribution. Current data-driven approaches to virtual flow metering (VFM) and bottomhole estimation typically treat each well independently or ignore the influence of well design on operational behaviour. We present WISE (Well Intelligence and Systems Engineering Foundation Model), a design-aware, physics-informed multi-task model that integrates three complementary mechanisms: Feature-wise Linear Modulation (FiLM) and cross-modal attention to condition operational embeddings on well design parameters; multi-task learning for simultaneous prediction of flow rates, bottomhole conditions, and flow regime classification; and structural mass conservation with soft physics constraints derived from well engineering principles. Evaluation on the ManyWells benchmark (2000 simulated wells, $10^6$ data points) demonstrates that design-aware models reduce VFM prediction error by up to $13\times$ compared to design-unaware baselines, and that physics constraints reduce negative flow predictions by 65%. Flow regime classification achieves 97.7% bottomhole accuracy, providing continuous well integrity monitoring without additional sensors. The methodology transfers to real operational data from five Equinor Volve producers (oil rate $R^2 = 0.89$, bottomhole pressure $R^2 = 0.98$, water rate $R^2 = 0.97$). The trained model additionally serves as a fast surrogate for integrity-aware well design optimisation over a 24-dimensional design space, with more than $1000\times$ speedup over drift-flux simulations. These results demonstrate that design awareness, physics enforcement, and multi-task learning are essential and complementary ingredients for foundation models intended to operate across large well portfolios.

Scaling EEG foundation models requires pooling data across heterogeneous electrode montages, a prerequisite both for larger pretraining corpora and for downstream deployment. We present the first systematic comparison of four channel adaptation methods (Conv1d projection, spherical spline interpolation (SSI), source-space decomposition, and Riemannian re-centering) across five pretrained EEG foundation models (5M--157M parameters), five downstream tasks, and two training regimes with 10--15 random seeds each. We find that rigid-montage models (BENDR, Neuro-GPT) require external adaptation, while flexible models (EEGPT, CBraMod) match or exceed it natively when fine-tuned but benefit from external methods under frozen-encoder deployment. A probe-SFT asymmetry exists: external adaptation can cause severe negative transfer during fine-tuning of flexible models. The optimal method is architecture-dependent (Conv1d for BENDR, SSI/Riemannian for Neuro-GPT, source-space decomposition for depression detection), and 5M-parameter CBraMod outperforms models up to 31$\times$ larger on 4/5 datasets, consistent with independent findings that compact EEG-specific architectures can match larger models.

Embodied foundation models have achieved significant breakthroughs in robotic manipulation, yet they still depend heavily on large-scale robot demonstrations. Although recent works have explored leveraging human data to alleviate this dependency, effectively extracting transferable knowledge remains a significant challenge due to the inherent embodiment gap between human and robot. We argue that the intention underlying human actions can serve as a powerful intermediate representation for bridging this gap. In this paper, we introduce a novel framework that explicitly learns and transfers human intention to facilitate robotic manipulation. Specifically, we model intention through gaze, as it naturally precedes physical actions and serves as an observable proxy for human intent. Our model is first pretrained on a large-scale egocentric human dataset to capture human intention and its synergy with action, followed by finetuning on a small set of robot and human data. During inference, the model adopts a Chain-of-Thought reasoning paradigm, sequentially predicting intention before executing the action. Extensive evaluations in simulation and real-world settings, across long-horizon and fine-grained tasks, and under few-shot and robustness benchmarks, show that our method consistently outperforms strong baselines, generalizes better, and achieves state-of-the-art performance. Project page: https://gazevla.github.io .

The emergence of large-scale pretrained foundation models has transformed computer vision, enabling strong performance across diverse downstream tasks. However, their potential for physics-based inverse problems, such as accelerated cardiac MRI reconstruction, remains largely underexplored. In this work, we investigate whether natural-domain foundation models can serve as effective image priors for accelerated cardiac MRI reconstruction, and compare the performance obtained against domain-specific counterparts such as BiomedCLIP. We propose an unrolled reconstruction framework that incorporates pretrained, frozen visual encoders, such as CLIP, DINOv2, and BiomedCLIP, within each cascade to guide the reconstruction process. Through extensive experiments, we show that while task-specific state-of-the-art reconstruction models such as E2E-VarNet achieve superior performance in standard in-distribution settings, foundation-model-based approaches remain competitive. More importantly, in challenging cross-domain scenarios, where models are trained on cardiac MRI and evaluated on anatomically distinct knee and brain datasets--foundation models exhibit improved robustness, particularly under high acceleration factors and limited low-frequency sampling. We further observe that natural-image-pretrained models, such as CLIP, learn highly transferable structural representations, while domain-specific pretraining (BiomedCLIP) provides modest additional gains in more ill-posed regimes. Overall, our results suggest that pretrained foundation models offer a promising source of transferable priors, enabling improved robustness and generalization in accelerated MRI reconstruction.

Clinical risk prediction using longitudinal medical data supports individualized care. Self-supervised foundation models have emerged as a promising approach for leveraging large-scale unlabeled healthcare records. In natural language processing, scaling laws suggest that larger models achieve predictably lower pretraining losses, supporting the foundation model paradigm. However, for structured medical data, characterized by a limited vocabulary and sparse observations, whether increasing model size consistently improves downstream predictions is unclear, as most studies evaluate only a single model scale. In this study, we evaluated the relationship between model scale and downstream task performance for structured medical foundation models. Using a random sample (2.3 million patients, 32 hospitals) from a nationwide 519-hospital Japanese claims database, we pretrained encoder-only Transformers at five scales (2.2M-101M parameters) for disease incidence and medication prediction. Downstream performance saturated at task-dependent thresholds: disease prediction benefited from larger models (32M-101M), whereas medication prediction saturated at 11M, reducing pretraining time by 178 h. Across all tasks, the best-performing model consistently outperformed a Light Gradient Boosting Machine baseline in the area under the precision-recall curve. These findings indicate that, unlike the monotonically decreasing pretraining loss, the optimal model size varied depending on task characteristics. This task-dependent saturation provides practical guidance for balancing predictive performance and computational cost in structured medical foundation models.

Driven by the transition towards a climate-neutral energy system, accurate energy time series forecasting is critical for planning and operation. Yet, it remains largely a dataset-specific task, requiring comprehensive training data, limiting scalability, and resulting in high model development and maintenance effort. Recently, foundation models that aim to learn generalizable patterns via extensive pretraining have shown superior performance in multiple prediction tasks. Despite their success and strong potential to address challenges in energy forecasting, their application in this domain remains largely unexplored. We address this gap by presenting the Foundation Models in Energy Time Series Forecasting (FETS) benchmark. We (1) provide a structured overview of energy forecasting use cases along three main dimensions: stakeholders, attributes, and data categories; (2) collect and analyze 54 datasets across 9 data categories, guided by typical stakeholder interests; (3) benchmark foundation models against classical machine learning approaches across different forecasting settings. Foundation models consistently outperform dataset-specific optimized machine learning approaches across all settings and data categories, despite the latter having seen the full historic target data during training. In particular, covariate-informed foundation models achieve the strongest performance. Further analysis reveals a strong correlation between predictive performance and spectral entropy, performance saturation beyond a certain context length, and improved performance at higher aggregation levels such as national load, district heating, and power grid data. Overall, our findings highlight the strong potential of foundation models as scalable and generalizable forecasting solutions for the energy domain, particularly in data-constrained and privacy-sensitive settings.

We propose Mochi, a Graph Foundation Model that addresses task unification and training efficiency by adopting a meta-learning based training framework. Prior models pre-train with reconstruction-based objectives such as link prediction, and assume that the resulting representations can be aligned with downstream tasks through a separate unification step such as class prototypes. We demonstrate through synthetic and real-world experiments that this procedure, while simple and intuitive, has limitations that directly affect downstream task performance. To address these limitations, Mochi pre-trains on few-shot episodes that mirror the downstream evaluation protocol, aligning the training objective with inference rather than relying on a post-hoc unification step. We show that Mochi, along with its more powerful variant Mochi++, achieves competitive or superior performance compared to existing Graph Foundation Models across 25 real-world graph datasets spanning node classification, link prediction, and graph classification, while requiring 8$\sim$27 times less training time than the strongest baseline.

Autonomous medical robots hold promise to improve patient outcomes, reduce provider workload, democratize access to care, and enable superhuman precision. However, autonomous medical robotics has been limited by a fundamental data problem: existing medical robotic datasets are small, single-embodiment, and rarely shared openly, restricting the development of foundation models that the field needs to advance. We introduce Open-H-Embodiment, the largest open dataset of medical robotic video with synchronized kinematics to date, spanning more than 50 institutions and multiple robotic platforms including the CMR Versius, Intuitive Surgical's da Vinci, da Vinci Research Kit (dVRK), Rob Surgical BiTrack, Virtual Incision's MIRA, Moon Surgical Maestro, and a variety of custom systems, spanning surgical manipulation, robotic ultrasound, and endoscopy procedures. We demonstrate the research enabled by this dataset through two foundation models. GR00T-H is the first open foundation vision-language-action model for medical robotics, which is the only evaluated model to achieve full end-to-end task completion on a structured suturing benchmark (25% of trials vs. 0% for all others) and achieves 64% average success across a 29-step ex vivo suturing sequence. We also train Cosmos-H-Surgical-Simulator, the first action-conditioned world model to enable multi-embodiment surgical simulation from a single checkpoint, spanning nine robotic platforms and supporting in silico policy evaluation and synthetic data generation for the medical domain. These results suggest that open, large-scale medical robot data collection can serve as critical infrastructure for the research community, enabling advances in robot learning, world modeling, and beyond.

Training large foundation models for agentic tasks is increasingly impractical due to the high computational costs, long iteration cycles, and rapid obsolescence as new models are continuously released. Instead of post-training massive models for every new task or domain, we propose Supplement Generation Training (SGT), a more efficient and sustainable strategy. SGT trains a smaller LLM to generate useful supplemental text that, when appended to the original input, helps the larger LLM solve the task more effectively. These lightweight models can dynamically adapt supplements to task requirements, improving performance without modifying the underlying large models. This approach decouples task-specific optimization from large foundation models and enables more flexible, cost-effective deployment of LLM-powered agents in real-world applications.

Scaling humanoid foundation models is bottlenecked by the scarcity of robotic data. While massive egocentric human data offers a scalable alternative, bridging the cross-embodiment chasm remains a fundamental challenge due to kinematic mismatches. We introduce UniT (Unified Latent Action Tokenizer via Visual Anchoring), a framework that establishes a unified physical language for human-to-humanoid transfer. Grounded in the philosophy that heterogeneous kinematics share universal visual consequences, UniT employs a tri-branch cross-reconstruction mechanism: actions predict vision to anchor kinematics to physical outcomes, while vision reconstructs actions to filter out irrelevant visual confounders. Concurrently, a fusion branch synergies these purified modalities into a shared discrete latent space of embodiment-agnostic physical intents. We validate UniT across two paradigms: 1) Policy Learning (VLA-UniT): By predicting these unified tokens, it effectively leverages diverse human data to achieve state-of-the-art data efficiency and robust out-of-distribution (OOD) generalization on both humanoid simulation benchmark and real-world deployments, notably demonstrating zero-shot task transfer. 2) World Modeling (WM-UniT): By aligning cross-embodiment dynamics via unified tokens as conditions, it realizes direct human-to-humanoid action transfer. This alignment ensures that human data seamlessly translates into enhanced action controllability for humanoid video generation. Ultimately, by inducing a highly aligned cross-embodiment representation (empirically verified by t-SNE visualizations revealing the convergence of human and humanoid features into a shared manifold), UniT offers a scalable path to distill vast human knowledge into general-purpose humanoid capabilities.

Modern artificial intelligence remains fundamentally divided between the continuous, probabilistic spaces of Foundation Models and the discrete, deterministic structures of Knowledge Graphs. While Retrieval-Augmented Generation (RAG) attempts to connect them by serializing graph data into text, we argue this lexical bridging is merely a superficial patch. In this paper, we formalize the underlying structural and geometric friction as the \textit{Impedance Mismatch}. By categorizing current neuro-symbolic integration strategies into a three-tiered hierarchy, we demonstrate that neither surface-level prompt injection nor continuous representation alignment can preserve the strict logical motifs required for reliable multi-hop reasoning. We define the specific mathematical limits, such as the Lexical Bottleneck and Topological Collapse, that show current architectures will eventually hallucinate or conflate semantic nodes. To achieve true semantic fusion, we propose a rigorous theoretical roadmap. We advocate for natively internalizing discrete symbolic structures through Structured Residual Streams, utilizing Vector Symbolic Architectures for latent sub-graph injection, and performing model updates via Orthogonal Subspace Editing. This actionable framework paves the way for models that seamlessly fuse the precision of symbolic logic with the expressivity of parametric memory.

Transformer-based scientific foundation models are increasingly deployed in high-stakes settings, but current architectures give deterministic outputs and provide limited support for calibrated predictive uncertainty. We propose Stochastic Attention, a sample average lightweight inference-time modification that randomizes attention by replacing softmax weights with normalized multinomial samples controlled by a single concentration parameter, and produces predictive ensembles without retraining. To set this parameter, we introduce a calibration objective that matches the stochastic attention output with the target, yielding an efficient univariate post-hoc tuning problem. We evaluate this mechanism on scientific foundation models for weather and time-series forecasting, as well as several regression tasks. Across benchmarks against uncertainty-aware baselines, we find that Sample Average Stochastic Attention achieves the strongest native calibration and the sharpest prediction intervals at comparable calibration, with adaptation costs nearly three orders of magnitude lower than the next-best baseline.

Source-free domain adaptation (SFDA) provides a practical solution to cross-subject EEG decoding by adapting source-pretrained models to unlabeled target domains without accessing source data. However, existing SFDA methods rely solely on the limited internal knowledge of source-pretrained models, leading to inferior cross-domain generalization and unreliable pseudo-labels. Although EEG Foundation Models (FMs) pretrained on large-scale data exhibit strong generalizability, their potential in SFDA remains largely unexplored. To this end, we propose FUSED, a Foundation-guided Source-free EEG Decoding framework that integrates a large-scale FM with a compact Specialist Model (SM) via dual-branch co-adaptation. Specifically, we introduce a Co-adaptation mechanism equipping both branches with linear and prototype views, enabling cross-branch pseudo-label generation. Additionally, we design a Consensus Filtering Mechanism that exploits the FM's inherent stability to identify high-quality samples, along with a Two-Stage Pseudo-Label Refinement scheme to suppress error accumulation through cross-branch arbitration. Finally, we calibrate the FM's decision boundaries via mutual information maximization with the SM, followed by knowledge distillation from FM to SM, forming a principled calibrate-then-distill pipeline. To our knowledge, FUSED is the first work to leverage EEG FMs within the SFDA framework for cross-subject EEG decoding. Extensive experiments across three EEG paradigms, including motor imagery, emotion recognition, and SSVEP, demonstrate consistent state-of-the-art performance, validating the effectiveness of foundation-guided synergy for robust and privacy-preserving EEG decoding.

Extracting standardized metallurgical metrics from microscopy images remains challenging due to complex grain morphology and the data demands of supervised segmentation. To bridge foundational computer vision with practical metallurgical evaluation, we propose an automated pipeline for dense instance segmentation and grain size estimation that adapts Cellpose-SAM to microstructures and integrates its topology-aware gradient tracking with an ASTM E112 Jeffries planimetric module. We systematically benchmark this pipeline against a classical convolutional network (U-Net), an adaptive-prompting vision foundation model (MatSAM) and a contemporary vision-language model (Qwen2.5-VL-7B). Our evaluations reveal that while the out-of-the-box vision-language model struggles with the localized spatial reasoning required for dense microscopic counting and MatSAM suffers from over-segmentation despite its domain-specific prompt generation, our adapted pipeline successfully maintains topological separation. Furthermore, experiments across progressively reduced training splits demonstrate exceptional few-shot scalability; utilizing only two training samples, the proposed system predicts the ASTM grain size number (G) with a mean absolute percentage error (MAPE) as low as 1.50%, while robustness testing across varying target grain counts empirically validates the ASTM 50-grain sampling minimum. These results highlight the efficacy of application-level foundation model integration for highly accurate, automated materials characterization. Our project repository is available at https://github.com/mueez-overflow/ASTM-Grain-Size-Estimator.

Vision-Language-Action (VLA) models drive next-generation autonomous systems, but training them requires scalable, high-quality annotations from complex environments. Current cloud pipelines rely on generic vision-language models (VLMs) that lack geometric reasoning and domain semantics due to their 2D image-text pretraining. To address this mismatch, we propose XEmbodied, a cloud-side foundation model that endows VLMs with intrinsic 3D geometric awareness and interaction with physical cues (e.g., occupancy grids, 3D boxes). Instead of treating geometry as auxiliary input, XEmbodied integrates geometric representations via a structured 3D Adapter and distills physical signals into context tokens using an Efficient Image-Embodied Adapter. Through progressive domain curriculum and reinforcement learning post-training, XEmbodied preserves general capabilities while demonstrating robust performance across 18 public benchmarks. It significantly improves spatial reasoning, traffic semantics, embodied affordance, and out-of-distribution generalization for large-scale scenario mining and embodied VQA.

Indoor robot navigation is often compromised by glass surfaces, which severely corrupt depth sensor measurements. While foundation models like Depth Anything 3 provide excellent geometric priors, they lack an absolute metric scale. We propose a training-free framework that leverages depth foundation models as a structural prior, employing a robust local RANSAC-based alignment to fuse it with raw sensor depth. This naturally avoids contamination from erroneous glass measurements and recovers an accurate metric scale. Furthermore, we introduce \ti{GlassRecon}, a novel RGB-D dataset with geometrically derived ground truth for glass regions. Extensive experiments demonstrate that our approach consistently outperforms state-of-the-art baselines, especially under severe sensor depth corruption. The dataset and related code will be released at https://github.com/jarvisyjw/GlassRecon.

With the rapid advancement of artificial intelligence, multi-agent systems (MASs) are evolving from classical paradigms toward architectures built upon large foundation models (LFMs). This survey provides a systematic review and comparative analysis of classical MASs (CMASs) and LFM-based MASs (LMASs). First, within a closed-loop coordination framework, CMASs are reviewed across four fundamental dimensions: perception, communication, decision-making, and control. Beyond this framework, LMASs integrate LFMs to lift collaboration from low-level state exchanges to semantic-level reasoning, enabling more flexible coordination and improved adaptability across diverse scenarios. Then, a comparative analysis is conducted to contrast CMASs and LMASs across architecture, operating mechanism, adaptability, and application. Finally, future perspectives on MASs are presented, summarizing open challenges and potential research opportunities.

Synthetic Aperture Radar (SAR) plays a critical role in maritime surveillance, yet deep learning for SAR analysis is limited by the lack of pixel-level annotations. This paper explores how general-purpose vision foundation models can enable zero-shot ship instance segmentation in SAR imagery, eliminating the need for pixel-level supervision. A YOLOv11-based detector trained on open SAR datasets localizes ships via bounding boxes, which then prompt the Segment Anything Model 2 (SAM2) to produce instance masks without any mask annotations. Unlike prior SAM-based SAR approaches that rely on fine tuning or adapters, our method demonstrates that spatial constraints from a SAR-trained detector alone can effectively regularize foundation model predictions. This design partially mitigates the optical-SAR domain gap and enables downstream applications such as vessel classification, size estimation, and wake analysis. Experiments on the SSDD benchmark achieve a mean IoU of 0.637 (89% of a fully supervised baseline) with an overall ship detection rate of 89.2%, confirming a scalable, annotation-efficient pathway toward foundation-model-driven SAR image understanding.

Recent generative AI models have achieved remarkable breakthroughs in language and visual understanding. However, although these models can generate realistic visual content, their spatial scale remains confined to bounded environments, preventing them from capturing how geographic environments evolve across thousands of kilometers or from modeling the spatial structure of the large-scale physical world. This limitation poses a critical challenge for ultra-wide-area spatial intelligence in Earth observation and simulation, revealing a deeper gap in generative AI: progress has relied primarily on scaling model parameters and training data, while overlooking spatial scale as a core dimension of intelligence. Here, motivated by this missing dimension, we investigate spatial scale as a new scaling axis in foundation models and present MetaEarth3D, the first generative foundation model capable of spatially consistent generation at the planetary scale. Taking optical Earth observation simulation as a testbed, MetaEarth3D enables the generation of multi-level, unbounded, and diverse 3D scenes spanning large-scale terrains, medium-scale cities, and fine-grained street blocks. Built upon 10 million globally distributed real-world training images, MetaEarth3D demonstrates both strong visual realism and geospatial statistical realism. Beyond generation, MetaEarth3D serves as a generative data engine for diverse virtual environments in ultra-wide spatial intelligence. We argue that this study may help empower next-generation spatial intelligence for Earth observation.

Industrial CAD workflows require robust, generalizable 3D geometric representations supporting accuracy and explainability. We introduce Shape, a self-supervised foundation model converting surface meshes into dense per-token embeddings. Shape combines a structured 3D latent grid, a multi-scale geometry-aware tokenizer (MAGNO) with cross-attention, and a transformer processor using grouped-query attention and RMSNorm. A learned reconstruction prior enables per-region attribution for explainable predictions. Pretraining uses masked-token reconstruction of normalized geometry statistics and multi-resolution contrastive consistency. The 10.9M-parameter backbone is pretrained on 61,052 CAD meshes from Thingi10K, MFCAD, and Fusion360. On a held-out split of 2,983 meshes, Shape achieves reconstruction R2 = 0.729 and 98.1% top-1 retrieval under the Wang-Isola protocol, with near-zero reconstruction train/val gap (contrastive scores use a larger evaluation pool). A 2x2 ablation on loss type and target-space normalization shows per-dimension normalization is critical: without it, performance collapses (R2 < 0.14, top-1 < 88%); with it, both losses succeed (R2 > 0.70, top-1 > 96%). Smooth-L1 offers secondary stability. Code, embeddings, and an interactive demo are released at https://github.com/simd-ai/shape.

The success of large foundation models is catalyzing a new paradigm for AI-native 6G network design: wireless foundation models for physical-layer design. However, existing models often operate on channel state information (CSI) in the spatial-temporal-frequency (STF) domain, where multipath components are superimposed and structurally entangled. This hinders the learning of a universal channel representation. Their reliance on global attention also incurs prohibitive overhead. In this paper, we propose AirFM-DDA, an Air-interface Foundation Model in the Delay-Doppler-Angle (DDA) domain. AirFM-DDA reparameterizes CSI into the DDA domain to resolve multipath components along physically meaningful axes and employs window-based attention with frame-structure-aware positional encoding. Extensive experiments demonstrate transferability across scenarios, tasks, datasets, and antenna configurations. For channel prediction and estimation, AirFM-DDA generalizes zero-shot to unseen cities, achieving average normalized mean-square error (NMSE) gains of 4.9-8.5 dB over the strongest baselines. With only 10% labeled data, it achieves average gains of 12.0 percentage points in Top-1 accuracy for beam prediction and 3.4 percentage points in F1 score for line-of-sight (LoS) identification. It further transfers across simulated datasets and adapts to measured data and different antenna arrays. Compared with global attention, window-based attention reduces training and inference costs by nearly an order of magnitude.

Non-stationary sequences arise naturally in control, forecasting, and decision-making. The data-generating process shifts at unknown times, and models must detect the change, discard or downweight obsolete evidence, and adapt to new dynamics on the fly. Transformer-based foundation models increasingly rely on in-context learning for time series forecasting, tabular prediction, and continuous control. As these models are deployed in non-stationary environments, understanding their ability to detect and adapt to regime shifts is important. We formalize this as an in-context change-point detection problem and formally establish the existence of transformer models that solve this problem. Our construction demonstrates that model complexity, in layers and parameters, depends on the level of information available about the change-point location, from no knowledge to knowing exact timing. We validate our results with experiments on synthetic linear regression and linear dynamical systems, where trained transformers match the performance of optimal baselines across information levels. We also show that encoding and incorporating changepoint knowledge indeed improves the real-world performance of a pretrained foundation models on infectious disease forecasting and on financial volatility forecasting around Federal Open Market Committee (FOMC) announcements without retraining, demonstrating practical applicability to real-world regime changes.

We present a Mixture-of-Experts-based foundation model applied to the GlueX DIRC detector at Jefferson Lab, demonstrating its utility as a unified framework for fast simulation, particle identification, and hit-level noise filtering of Cherenkov photons. By leveraging a single shared transformer backbone across all tasks, the approach eliminates the fragmentation of task-specific pipelines while maintaining competitive-and in several cases superior-performance relative to established methods. The model operates directly on low-level detector inputs, performing hit-by-hit autoregressive generation over split spatial and temporal vocabularies with continuous kinematic conditioning, and supports class-conditional generation of pions and kaons through its Mixture-of-Experts architecture. We benchmark against the standard geometrical reconstruction and prior deep learning methods across the full kinematic phase space of the GlueX DIRC, demonstrating that the foundation model framework transfers effectively to this detector without architectural modification. This work positions the foundation model as a practical and scalable alternative to the suite of task-specific models currently proposed for GlueX DIRC analysis.

Landslide detection from high resolution satellite imagery is a critical task for disaster response and risk assessment, yet the relative effectiveness of modern segmentation architectures and finetuning strategies for this problem remains insufficiently understood. In this work, we present a systematic benchmarking study of convolutional neural networks, transformer based segmentation models, and large pre-trained foundation models for landslide detection. Using the Globally Distributed Coseismic Landslide Dataset (GDCLD) dataset, we evaluate representative CNN- and transformer-based segmentation models alongside large pretrained foundation models under consistent training and evaluation protocols. In addition, we compare full fine-tuning with parameter-efficient fine-tuning methods, including LoRA and AdaLoRA, to assess their performance efficiency tradeoffs. Experimental results show that transformer-based models achieve strong segmentation performance, while parameter efficient finetuning reduces trainable parameters by up to 95% with comparable accuracy to full finetuning. We further analyze generalization under distribution shift by comparing validation and held-out test performance.

We introduce neuralCAD-Edit, the first benchmark for editing 3D CAD models collected from expert CAD engineers. Instead of text conditioning as in prior works, we collect realistic CAD editing requests by capturing videos of professional designers, interacting directly with CAD models in CAD software, while talking, pointing and drawing. We recruited ten consenting designers to contribute to this contained study. We benchmark leading foundation models against human CAD experts carrying out edits, and find a large performance gap in both automatic metrics and human evaluations. Even the best foundation model (GPT 5.2) scores 53% lower (absolute) than CAD experts in human acceptance trials, demonstrating the challenge of neuralCAD-Edit. We hope neuralCAD-Edit will provide a solid foundation against which 3D CAD editing approaches and foundation models can be developed. Code/data: https://autodeskailab.github.io/neuralCAD-Edit

Oil and gas drilling operations generate extensive time-series data from surface sensors, yet accurate real-time prediction of critical downhole metrics remains challenging due to the scarcity of labelled downhole measurements. This systematic mapping study reviews thirteen papers published between 2015 and 2025 to assess the potential of Masked Autoencoder Foundation Models (MAEFMs) for predicting downhole metrics from surface drilling data. The review identifies eight commonly collected surface metrics and seven target downhole metrics. Current approaches predominantly employ neural network architectures such as artificial neural networks (ANNs) and long short-term memory (LSTM) networks, yet no studies have explored MAEFMs despite their demonstrated effectiveness in time-series modeling. MAEFMs offer distinct advantages through self-supervised pre-training on abundant unlabeled data, enabling multi-task prediction and improved generalization across wells. This research establishes that MAEFMs represent a technically feasible but unexplored opportunity for drilling analytics, recommending future empirical validation of their performance against existing models and exploration of their broader applicability in oil and gas operations.

EEG foundation models (EFMs) achieve strong cross-subject and cross-task generalization through large-scale pretraining and downstream fine-tuning. Through empirical analysis, we observe that (i) task-adapted EFMs provide strong decoding performance but incur substantial overhead when retained as inference backbones, making knowledge distillation a natural route for optimizing compact students; and (ii) direct distillation from a fixed teacher representation underutilizes EFM knowledge, as task-discriminative information is distributed across intermediate layers rather than concentrated in the final layer. These observations motivate DLink (Distilling Layer-wise and Dominant Knowledge), a spectrally guided distillation framework with input-conditioned layer routing for transferring EFM knowledge into compact students. DLink uses a lightweight router to aggregate teacher layers for each input, and aligns magnitude and phase spectra to mitigate compression-induced spectral distortion in learned representations. The routed teacher knowledge is internalized by a project-then-compress student; the teacher and router are used only during training. Experiments on four EEG benchmarks show that DLink improves matched compact students and remains competitive with lightweight baselines, narrowing the gap to fine-tuned EFMs while substantially reducing parameters, FLOPs, and CPU-only inference latency.

Foundation models are used to extract transferable representations from large amounts of unlabeled data, typically via self-supervised learning (SSL). However, many of these models rely on architectures that offer limited interpretability, a critical issue in high-stakes domains such as medical imaging. We propose \model, a foundation model that is interpretable-by-design via a BagNet backbone whose small receptive fields generate class evidence maps that are faithful to the model's decision-making process. Additionally, \model{} incorporates a $2D$ projection layer during pretraining that enables direct visualization of the representation space, providing a dataset-level view of the learned structure including meaningful clinical clusters as well as potential spurious correlations. We trained \model{} on over 800,000 color fundus photographs from various sources to learn generalizable representations for different downstream tasks. Our model achieves performance comparable to RETFound, which has $16\times$ more parameters, while providing interpretable predictions on out-of-distribution data. These results suggest that large-scale SSL pretraining paired with inherent interpretability can lead to robust representations for retinal imaging. Code and pretrained models are available at \href{https://anonymous.4open.science/r/dual-ifm-3D5A/README.md}{www.anonymous.4open.science/dual-IFM}.

Recent depth foundation models trained on perspective imagery achieve strong performance, yet generalize poorly to 360$^\circ$ images due to the substantial geometric discrepancy between perspective and panoramic domains. Moreover, fully fine-tuning these models typically requires large amounts of panoramic data. To address this issue, we propose RePer-360, a distortion-aware self-modulation framework for monocular panoramic depth estimation that adapts depth foundation models while preserving powerful pretrained perspective priors. Specifically, we design a lightweight geometry-aligned guidance module to derive a modulation signal from two complementary projections (i.e., ERP and CP) and use it to guide the model toward the panoramic domain without overwriting its pretrained perspective knowledge. We further introduce a Self-Conditioned AdaLN-Zero mechanism that produces pixel-wise scaling factors to reduce the feature distribution gap between the perspective and panoramic domains. In addition, a cubemap-domain consistency loss further improves training stability and cross-projection alignment. By shifting the focus from complementary-projection fusion to panoramic domain adaptation under preserved pretrained perspective priors, RePer-360 surpasses standard fine-tuning methods while using only 1% of the training data. Under the same in-domain training setting, it further achieves an approximately 20% improvement in RMSE. The code is available at https://github.com/munimo/RePer360.

General-purpose large language models (LLMs) that rely on in-context learning do not reliably deliver the scientific understanding and performance required for drug discovery tasks. Simply increasing model size or introducing reasoning tokens does not yield significant performance gains. To address this gap, we introduce the MMAI Gym for Science, a one-stop shop molecular data formats and modalities as well as task-specific reasoning, training, and benchmarking recipes designed to teach foundation models the 'language of molecules' in order to solve practical drug discovery problems. We use MMAI Gym to train an efficient Liquid Foundation Model (LFM) for these applications, demonstrating that smaller, purpose-trained foundation models can outperform substantially larger general-purpose or specialist models on molecular benchmarks. Across essential drug discovery tasks - including molecular optimization, ADMET property prediction, retrosynthesis, drug-target activity prediction, and functional group reasoning - the resulting model achieves near specialist-level performance and, in the majority of settings, surpasses larger models, while remaining more efficient and broadly applicable in the domain.

Generalist pathology foundation models (PFMs), pretrained on large-scale multi-organ datasets, have demonstrated remarkable predictive capabilities across diverse clinical applications. However, their proficiency on the full spectrum of clinically essential tasks within a specific organ system remains an open question due to the lack of large-scale validation cohorts for a single organ as well as the absence of a tailored training paradigm that can effectively translate broad histomorphological knowledge into the organ-specific expertise required for specialist-level interpretation. In this study, we propose BRIGHT, the first PFM specifically designed for breast pathology, trained on over 51,000 breast whole-slide images derived from a cohort of over 40,000 patients across 19 hospitals. BRIGHT employs a collaborative generalist-specialist framework to capture both universal and organ-specific features. To comprehensively evaluate the performance of PFMs on breast oncology, we curate the largest multi-institutional cohorts to date for downstream task development and evaluation, comprising over 25,000 WSIs across 10 hospitals. The validation cohorts cover the full spectrum of breast pathology across 25 distinct clinical tasks spanning diagnosis, biomarker prediction, treatment response and survival prediction. Extensive experiments demonstrate that BRIGHT outperforms five leading generalist PFMs, achieving state-of-the-art (SOTA) performance in 25 of 25 internal validation tasks and in 4 of 11 external validation tasks with excellent heatmap interpretability. By evaluating on large-scale validation cohorts, this study not only demonstrates BRIGHT's clinical utility in breast oncology but also validates a collaborative generalist-specialist paradigm, providing a scalable template for developing PFMs on a specific organ system, accelerating the translation of foundation models into ...

Polysomnography (PSG) provides the gold standard for sleep assessment but suffers from substantial heterogeneity across recording devices and cohorts. There have been growing efforts to build general-purpose foundation models (FMs) for sleep physiology, but lack an in-depth understanding of the pre-training process and scaling patterns that lead to more generalizable sleep FMs. To fill this gap, we curate a massive corpus of 166,500 hours of sleep recordings from nine public sources and establish SleepBench, a comprehensive, fully open-source benchmark. Leveraging SleepBench, we systematically evaluate four families of self-supervised pre-training objectives and uncover three critical findings: (1) existing FMs fail to generalize to missing channels at inference; (2) channel-invariant feature learning is essential for pre-training; and (3) scaling sample size, model capacity, and multi-source data mixture consistently improves downstream performance.With an enhanced pre-training and scaling recipe, we introduce OSF, a family of sleep FMs that achieves state-of-the-art performance across nine datasets on diverse sleep and disease prediction tasks. Further analysis of OSF also reveals intriguing properties in sample efficiency, hierarchical aggregation, and cross-dataset scaling.

Artificial intelligence built on large foundation models has transformed language understanding, computer vision, and reasoning, yet these systems remain isolated and cannot readily share their capabilities. Coordinating the complementary strengths of independently developed, black-box foundation models is essential for trustworthy intelligent systems, yet no established method exists. Here we show that such coordination can be achieved through a meta-ensemble framework termed StackingNet, which aggregates the output predictions of independent models at inference. StackingNet improves accuracy, reduces individual-model error and group-wise disparities, ranks model reliability, and identifies or prunes models that degrade performance, all without access to internal parameters or training data. Across language comprehension, visual attribute estimation, and academic paper rating, it consistently outperforms individual models and classic ensembles, with gains that persist when the base models are uniformly strong. These gains stem from variance reduction and consensus alignment among independent models rather than from any emergent group cognition, and they widen as the model pool grows more diverse. By turning model diversity from a source of inconsistency into a resource for cooperation, StackingNet offers a practical path toward coordinated artificial intelligence, where progress emerges not only from larger single models but from principled cooperation among many specialized ones.

Although foundation models have achieved remarkable success in general domains, applying them to electroencephalography (EEG) analysis is constrained by substantial data requirements and large parameter counts, which incur prohibitive computational costs and impede deployment in resource-constrained clinical environments. General-purpose automated machine learning frameworks are likewise ill-suited to this domain, since exploration within an unbounded programmatic space fails to incorporate essential neurophysiological priors and frequently yields neuroscientifically implausible solutions. We therefore propose NeuroWeaver, a unified autonomous evolutionary agent that generalizes across diverse EEG datasets and tasks by reformulating pipeline engineering as a discrete constrained optimization problem solved through large language model (LLM)-driven generation of executable code. A Domain-Informed Subspace Initialization confines the search to a neuroscientifically plausible manifold, while a Multi-Objective Evolutionary Optimization dynamically balances performance, novelty, and efficiency via self-reflective refinement. Across five heterogeneous benchmarks, NeuroWeaver synthesizes lightweight pipelines that outperform state-of-the-art task-specific methods on nearly all metrics and attain accuracy comparable to large-scale foundation models, even surpassing them on the HMC and Workload benchmarks with only $0.18$M and $0.011$M parameters, respectively.

Entity alignment (EA) is critical for knowledge graph (KG) fusion. Existing EA models lack transferability and are incapable of aligning unseen KGs without retraining. While using graph foundation models (GFMs) offer a solution, we find that directly adapting GFMs to EA remains largely ineffective. This stems from a critical "reasoning horizon gap": unlike link prediction in GFMs, EA necessitates capturing long-range dependencies across sparse and heterogeneous KG structuresTo address this challenge, we propose a EA foundation model driven by a parallel encoding strategy. We utilize seed EA pairs as local anchors to guide the information flow, initializing and encoding two parallel streams simultaneously. This facilitates anchor-conditioned message passing and significantly shortens the inference trajectory by leveraging local structural proximity instead of global search. Additionally, we incorporate a merged relation graph to model global dependencies and a learnable interaction module for precise matching. Extensive experiments verify the effectiveness of our framework, highlighting its strong generalizability to unseen KGs.

Foundation models have transformed machine learning for language and vision, but achieving comparable impact in physical simulation remains a challenge. Data heterogeneity and unstable long-term dynamics inhibit learning from sufficiently diverse dynamics, while varying resolutions and dimensionalities challenge efficient training on modern hardware. Through empirical and theoretical analysis, we incorporate new approaches to mitigate these obstacles, including a harmonic-analysis-based stabilization method, load-balanced distributed 2D and 3D training strategies, and compute-adaptive tokenization. Using these tools, we develop Walrus, a transformer-based foundation model developed primarily for fluid-like continuum dynamics. Walrus is pretrained on nineteen diverse scenarios spanning astrophysics, geoscience, rheology, plasma physics, acoustics, and classical fluids. Experiments show that Walrus outperforms prior foundation models on both short and long term prediction horizons on downstream tasks and across the breadth of pretraining data, while ablation studies confirm the value of our contributions to forecast stability, training throughput, and transfer performance over conventional approaches. Code and weights are released for community use.