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AI evaluation results are produced at scale but reported inconsistently across leaderboards, model cards, benchmark papers, and company blogs. The cost is interpretive: readers cannot reliably compare results across sources, identify what a report omits, or trace an aggregate claim to its underlying evidence. Recent efforts address isolated components but leave three gaps: they cover only narrow slices of the evaluation lifecycle and do not compose into a single interpretable record; they specify static representations that do not differentiate the questions different stakeholders bring to the same evidence; and they remain proposals on paper, lacking the extraction infrastructure required for adoption at scale. We present \EvalCards{}, an operational reporting layer that composes benchmark metadata, evaluation run data, and model metadata into a unified record. We (1) derive a reporting schema from a structured review of 52 papers and 10 stakeholder interviews, (2) implement four interpretive signals (reproducibility, documentation completeness, provenance and risk, and score comparability), rendered through reader modes calibrated to research and non-research audiences, and (3) deploy a monitoring tool that applies \EvalCards{} across 5,816 models, 635 benchmarks, and 101,843 results, surfacing systematic gaps in current reporting practice.

We propose a unified mathematical framework for a geometric understanding of concept learning and neuron interpretation in sparse autoencoders (SAEs). While SAEs improve interpretability of neural networks by learning sparse feature representations, a principled definition of ''concept'' and ''learning'' remains unclear. We formalize concepts as sets of data points and cast concept learning as a set-alignment problem between human-defined and model-induced concepts. This formulation distinguishes three increasingly strong notions of learning -- detection, separation, and approximation -- and yields geometric conditions, error bounds, and capacity constraints for when concepts can be represented by individual neurons or multi-neuron units. It also provides a set-theoretic account for common SAE phenomena, including feature splitting, feature absorption, feature families, and hierarchical concepts. Finally, we connect concept learning and neuron interpretation through formal concept analysis, showing that the two directions need not agree and that their many-to-many structure can be organized by concept lattices. Experiments on synthetic data with ReLU and Top-$K$ SAEs illustrate the theory and reveal the effects of SAE size and sparsity on concept learning.

A central goal of cognitive neuroscience is to characterize the features that are represented by human language cortex. Artificial language models (LMs) have emerged as a powerful tool to address this challenge, but studies relating biological and artificial representations are often criticized as relating one black box to another. The present work introduces Augmented Sparse Encoding Models, an encoding framework that replaces dense LM hidden states with hierarchically-organized sparse autoencoder (SAE) features, while explicitly including surprisal as a predictor. Using this approach, we (i) produce interpretations of neural responses and (ii) test whether model-brain alignment reflects primary or idiosyncratic variation in LM representations. Using a high-field 7T fMRI dataset of eight participants listening to 200 linguistically diverse sentences, we first validate our modeling framework by recovering previous interpretations of voxel populations tuned to processing difficulty and meaning abstractness. We then interpret a previously-uncharacterized (but reliable) voxel population and find that it is tuned to people-related content. Next, we show that the fronto-temporal human language network is predicted by a common set of features across its constituent regions, but find that frontal regions are relatively well-explained by surprisal alone, even in the absence of LM-based features. Finally, we show that brain responses during language processing are not merely predictable from an arbitrary set of LM features. Rather, brain responses are best explained by the features that tend to capture the most general information encoded in LM representations, suggesting a nontrivial correspondence between brain and LM language representation.

Style representation learning is a powerful tool for authorship analysis and modeling writing style, yet the latent nature of learned representations makes them difficult to interpret. Recent work has attempted to explain these representations by generating natural language descriptions with large language models (LLMs) conditioned on input text. However, such descriptions are often prone to the LLM's biases and hallucinations, and they lack an explicit objective and practical utility. In this work, we propose a novel framework for interpreting style representations through style-eliciting prompts: natural language instructions designed to steer LLMs to generate text that reflects specific stylistic attributes. We curate 1,010 distinct style features spanning 26 stylistic categories and construct a dataset by prompting an LLM to generate text conditioned on these features. Using this data, we train a decoder to generate a style prompt from the style representation of the generated text. We evaluate our approach on three tasks: (1) recovering original style prompts from generated text, (2) generating text in the same style using the recovered prompts, and (3) steering LLM outputs to match the style of human-written texts. Experiments demonstrate that our method consistently outperforms strong baselines that directly prompt LLMs with target text, achieving superior performance in both style description and style imitation. These results highlight that style-eliciting prompts can provide a practical and interpretable interface to stylistic information encoded in style representations.

Sparse autoencoder (SAE) features are increasingly used to interpret language models, with auto-generated natural-language labels serving as the primary interface for understanding what each feature represents. We ask whether these labels generalize: does a feature labeled for a concept actually track that concept across languages and scripts? Using Serbian digraphia as a controlled testbed--the same language written in both Latin and Cyrillic via deterministic transliteration--we first find that SAE feature sets activated by the same content in different languages, scripts, and wordings share substantial overlap (mean Jaccard 0.39 vs. 0.13 random baseline, peaking at 0.57), suggesting genuine cross-lingual semantic features. We then test whether auto-interpretation labels keep pace. They often do not: features whose labels describe semantic content miss the same meaning in Serbian up to 4x more often thanwithin English, and miss Serbian Cyrillic more than Serbian Latin--two scripts that are deterministic transliterations of each other--suggesting the failures align with how well each form is represented in training. The gap grows with network depth, yet the labels give no indication that they fail. These results suggest that auto-interpretation labels may reflect a feature's behavior on well-represented inputs rather than the concept itself.

This study examines how persona prompting shapes language generated by two multimodal large language models in urban perception, a setting for examining subjective interpretations of shared visual evidence. We organize outputs into three functional layers: descriptive grounding (captions), intermediate semantic layer (perception tags), and interpretive framing (justifications). Using approximately 60,000 persona-conditioned annotations from each of two MLLMs, Qwen3-VL and Gemma4, we find that captions converge strongly across persona profiles and show only small attribute-associated differences. Justifications vary substantially more: economic status produces the largest difference in both models, with political orientation and personality also prominent. Paired image-level comparisons confirm larger justification than caption differences for these three attributes. For perception tags, personas sharing the same attribute level produce more similar tag sets than personas with different attribute levels, with the largest separation observed for economic status. Exploratory topic analysis further suggests persona-specific evaluative emphasis. Across models, profile-pair similarity patterns are strongly correlated for all three output types, although agreement is lowest for justifications. Overall, persona prompting affects interpretive framing more strongly than descriptive grounding.

Recent advances in deep learning have enabled increasingly accurate electroencephalography (EEG)-based classification of Major Depressive Disorder (MDD), but the decision-making processes of high-capacity models remain difficult to interpret. This study investigates multiple post-hoc explainability methods applied to an InceptionTime architecture trained for EEG-based MDD detection. The analysis includes Shapley-based, gradient-based, and perturbation-based attribution approaches: DeepSHAP, Integrated Gradients, GradCAM, Occlusion, and Permutation Feature Importance. Explainability analysis was performed within a subject-level stratified 5-fold cross-validation framework using global attribution aggregation across EEG segments and subjects. The evaluated methods revealed partially convergent attribution patterns, with recurring emphasis on frontal, temporal, and posterior EEG regions, particularly in the right hemisphere. Quantitative comparison demonstrated substantial agreement between gradient- and perturbation-based approaches, while DeepSHAP produced comparatively distinct attribution distributions. At the same time, variability between explainability methods highlighted the influence of methodological assumptions on the resulting explanations. Overall, the results suggest that different post-hoc explainability approaches capture partially overlapping relevance structures in EEG-based deep learning models for depression detection. Although the observed attribution patterns are broadly consistent with several previous EEG studies of MDD, the analysis should be interpreted as exploratory rather than evidence of definitive neurophysiological biomarkers or clinical applicability. The study highlights both the usefulness and limitations of post-hoc explainability for interpreting black-box EEG classifiers in psychiatric applications.

An agent must act on the situation before it, learn what it cannot yet represent, and model other agents well enough to coordinate. These faculties are usually realized by separate mechanisms, yet they share a failure mode: the situation can exceed what the agent can currently represent, and the honest response is then a principled refusal that says what was missing. We develop a small cognitive architecture in which these limits arise from a single quantity. An Interpretation-Decision Unit (IDU) interprets a content vector through a family of regimes - local representational frames with private bases - and decides which actions it licenses; a scalar residual of the content against the active regimes' representational scope drives the unit. Low residual with a clean licensing emits an action; otherwise the unit re-interprets, attempts a description-length-justified expansion, or halts with a typed, witnessed terminal. We prove the unit is total and deterministic: for any content and fixed configuration it halts in finitely many bounded-cost steps with a unique terminal witness, so abstention carries its cause by construction. By binding the architecture's open parameters without changing its mechanics, the same residual-against-scope constraint recovers three documented phenomena at three scopes: the typology of not-knowing (typed abstention); a forced misunderstanding between agents, localized to one shared concept and invisible to the agent committing it (bounded empathy); and prerequisite dependence in learning derived from a bounded focus window rather than posited (developmental prerequisites). Each instantiation is worked for a natural and an artificial agent and states a falsifiable prediction, so one constraint can model limits in both human and machine cognition. The account contributes a unification and a notion of accountable abstention, typed and witnessed by construction.

Chain-of-Thought (CoT) prompting has shown promise in enhancing the reasoning capabilities of large language models (LLMs) on text-attributed graphs (TAGs). This work reframes CoT-based graph learning through the principle of clustering as reasoning, offering a $k$-means interpretation of how iterative reasoning operates over graph-structured data. We observe that existing graph CoT methods rely on disjoint architectures and fixed graph representations, limiting step-by-step semantic-topological interaction and interpretability. To overcome this limitation, we propose a unified framework named KCoT that integrates CoT reasoning with graph representation learning. Our key theoretical result reveals a formal mathematical correspondence between a Transformer block and the $k$-means algorithm, allowing reasoning to be interpreted as iterative assignment and update steps. Based on this insight, we introduce a Semantic Discriminating Prompt that explicitly formulates these steps as structured CoT reasoning, together with a structure-grounded alignment strategy to fuse topological priors with evolving thought-conditioned representations. Experiments on standard benchmarks demonstrate consistent improvements over state-of-the-art methods, validating clustering as a principled mechanism for CoT-based graph learning.

Large language models can consult information that fixed static analyzers cannot, such as documentation, current security advisories, version-specific metadata, and informal API contracts. This makes LLMs a compelling option for program analyses that depend on information beyond the source program, or that are otherwise not amenable to conventional static analyzers. However, directly asking an LLM for a one-shot whole-program analysis is brittle because it compresses many evidence-dependent judgments into a single opaque answer, rather than exposing which conclusions are supported or disputed and using intermediate findings to guide later, more focused searches. In this paper, we propose agentic interpretation, a framework that brings the discipline of lattice-based static analysis to LLM-driven program reasoning. At a high level, agentic interpretation decomposes a high-level analysis goal into localized claims, and tracks the LLM's judgment about each claim in a finite-height lattice. A worklist algorithm governs how claims and their judgments evolve during the analysis. We introduce a formal model of agentic interpretation, explore the design space it opens, and illustrate the approach with a worked example analyzing code that depends on opaque third-party components.

Protein language models such as ESM-2 learn rich residue representations that achieve strong performance on protein function prediction, but their features remain difficult to interpret as structural $\&$ evolutionary signals are encoded in dense latent spaces. We propose a plug-$\&$-play framework that projects ESM-2 representations onto protein contact graphs $\&$ applies $\textbf{SoftBlobGIN}$, a lightweight Graph Isomorphism Network with differentiable Gumbel-softmax substructure pooling, to perform structure-aware message passing $\&$ learn coarse functional substructures for downstream prediction tasks. Across enzyme classification, SoftBlobGIN achieves 92.8% accuracy $\&$ 0.898 macro-F1. Unlike post hoc analysis of protein language models alone, our method produces directly auditable structural explanations: GNNExplainer recovers biologically meaningful active-site residues, spatially localized functional clusters, $\&$ catalytic contact patterns. On binding-site detection, SoftBlobGIN improves residue AUROC from $0.885$ using an ESM-2 linear probe to $0.983$, indicating that these structural explanations are not recoverable from language-model features alone. Learned blob partitions provide an additional layer of interpretability by automatically grouping residues into functional substructures, with blobs containing annotated active-site residues showing $1.85\times$ higher importance than other blobs ($ρ{=}0.339$, $p{=}0.009$), without any active-site supervision. Our framework requires no retraining of the language model, adds only $\sim$1.1M parameters, $\&$ generalises across ProteinShake tasks, achieving $F_{\max}$ of $0.733$ on Gene Ontology prediction $\&$ AUROC of $0.969$ on binding-site detection. We position this as an interpretable structural companion to protein language models that makes their predictions more transparent $\&$ auditable.

Modern searches for physics beyond the Standard Model produce rapidly expanding literature containing heterogeneous information, including textual analyses, numerical datasets, and graphical exclusion limits. Integrating these distributed sources remains a time-consuming and manual process for physicists. We present HEP-CoPilot, a retrieval-augmented multi-agent AI framework for the exploration and interpretation of high-energy physics literature. The system unifies textual information from publications, structured experimental data from HEPData, and reconstructed physics plots within a multimodal retrieval and reasoning architecture. By combining retrieval-augmented language models with coordinated agent workflows, it enables evidence-grounded reasoning over experimental analyses and structured interpretation of collider results. We evaluate the framework on recent CMS searches for physics beyond the Standard Model. Case studies show that HEP-CoPilot can retrieve relevant measurements, reconstruct exclusion limits directly from HEPData records, and perform cross-paper comparisons of experimental constraints. This enables consistent, physics-aware comparison across analyses without manual data integration. These results demonstrate that retrieval-augmented AI systems can function as scientific co-pilots for particle physics, facilitating navigation of complex literature, structuring heterogeneous evidence, and accelerating the interpretation pipeline for new physics searches.

Ultrasound interpretation requires both precise lesion localization and holistic clinical reasoning, yet existing methods typically excel at only one of these capabilities: specialized detectors offer strong localization but limited reasoning, whereas multimodal large language models (MLLMs) provide flexible reasoning but weak grounding in specialized medical domains. We present Echo-α, an agentic multimodal reasoning model for ultrasound interpretation that unifies these strengths within an invoke-and-reason framework. Echo-α is trained to coordinate organ-specific detector outputs, integrate them with global visual context, and convert the resulting evidence into grounded diagnostic decisions beyond detector-only inference. This behavior is established through a nine-task supervised curriculum and then refined by sequential reinforcement learning under different reward trade-offs, yielding Echo-α-Grounding for lesion anchoring and Echo-α-Diagnosis for final diagnosis. On multi-center renal and breast ultrasound benchmarks, Echo-α outperforms competitive baselines on both grounding and diagnosis. In particular, on cross-center test sets, Echo-α-Grounding attains 56.73%/43.78% F1@0.5 and Echo- α-Diagnosis reaches 74.90%/49.20% overall accuracy on renal/breast ultrasound. These results suggest that agentic multimodal reasoning can turn specialized detectors into verifiable clinical evidence, offering a practical route toward ultrasound AI systems that are more accurate, interpretable, and transferable. The repository is at https://github.com/MiliLab/Echo-Alpha.

Privacy policies are essential for users to understand how service providers handle their personal data. However, these documents are often long and complex, as well as filled with technobabble and legalese, causing users to unknowingly accept terms that may even contradict the law. While summarizing and interpreting these privacy policies is crucial, there is a lack of high-quality English parallel corpus optimized for legal clarity and readability. To address this issue, we introduce APPSI-139, a high-quality English privacy policy corpus meticulously annotated by domain experts, specifically designed for summarization and interpretation tasks. The corpus includes 139 English privacy policies, 15,692 rewritten parallel corpora, and 36,351 fine-grained annotation labels across 11 data practice categories. Concurrently, we propose TCSI-pp-V2, a hybrid privacy policy summarization and interpretation framework that employs an alternating training strategy and coordinates multiple expert modules to effectively balance computational efficiency and accuracy. Experimental results show that the hybrid summarization system built on APPSI-139 corpus and the TCSI-pp-V2 framework outperform large language models, such as GPT-4o and LLaMA-3-70B, in terms of readability and reliability. The source code and dataset are available at https://github.com/EnlightenedAI/APPSI-139.

Shared accountability records are often used by parties who may never agree about causation, responsibility, or normative interpretation. For such records, neutrality cannot be achieved by omitting contested information, because accountability requires preserving the claims parties made, with their sources and provenance. Nor can neutrality be achieved by asserting one contested interpretation as the shared base. This paper defines a neutral substrate as a shared representational layer that provides stable reference while making no object-level substrate-layer commitments to causal or normative propositions. The central design constraint is that, when causal and normative propositions are contestable across admissible frameworks and the substrate's referential commitments are common ground, the substrate's neutrality is guaranteed at design time if and only if its foundational layer is restricted to those referential commitments and attribution propositions whose attributional basis is fixed by them. Causal and normative content may still be represented, but not as object-level foundational-layer commitments: it may appear there only as the content of attributed assertions with provenance, made by some identified framework, source, agent, institution, record, or document. The representational machinery used here is standard: reification, attribution, and provenance. The contribution is the constraint: a checkable condition on the foundational layer of a shared record, stated together with the assumptions it depends on and the boundary condition under which the constraint does not apply. A neutral substrate says enough to preserve accountability, but it does not turn one party's interpretation into an object-level substrate-layer commitment. The constraint does not apply at that layer when the referential regime or attributional basis is contested among the frameworks in play.

Chest X-ray (CXR) plays a pivotal role in clinical diagnosis, and a variety of task-specific and foundation models have been developed for automatic CXR interpretation. However, these models often struggle to adapt to new diagnostic tasks and complex reasoning scenarios. Recently, LLM-based agent models have emerged as a promising paradigm for CXR analysis, enhancing model's capability through tool coordination, multi-step reasoning, and team collaboration, etc. However, existing agents often rely on a single diagnostic pipeline and lack mechanisms for assessing tools' reliability, limiting their adaptability and credibility. To this end, we propose CXRAgent, a director-orchestrated, multi-stage agent for CXR interpretation, where a central director coordinates the following stages: (1) Tool Invocation: The agent strategically orchestrates a set of CXR-analysis tools, with outputs normalized and verified by the Evidence-driven Validator (EDV), which grounds diagnostic outputs with visual evidence to support reliable downstream diagnosis; (2) Diagnostic Planning: Guided by task requirements and intermediate findings, the agent formulates a targeted diagnostic plan. It then assembles an expert team accordingly, defining member roles and coordinating their interactions to enable adaptive and collaborative reasoning; (3) Collaborative Decision-making: The agent integrates insights from the expert team with accumulated contextual memories, synthesizing them into an evidence-backed diagnostic conclusion. Experiments on various CXR interpretation tasks show that CXRAgent delivers strong performance, providing visual evidence and generalizes well to clinical tasks of different complexity. Code and data are valuable at this \href{https://github.com/laojiahuo2003/CXRAgent/}{link}.

Medical report understanding from real-world document images is essential for generating patient-facing explanations and enabling structured information exchange in clinical systems. Existing VLMs and LLMs have shown strong performance on document understanding, but structured understanding of medical reports remains insufficiently benchmarked. Therefore, we introduce MedRepBench, a benchmark with 1,925 de-identified Chinese medical report images spanning diverse departments, patient demographics, and acquisition formats. In MedRepBench, we mainly focus on report-grounded interpretation rather than evaluating diagnostic reasoning, treatment recommendation, or the integration of patient history. The interpretation is defined as structured extraction of report fields (e.g., item, value, unit, reference range, abnormal flag) plus a patient-facing explanation grounded strictly in the report content. The benchmark primarily evaluates end-to-end VLMs, and also includes a controlled text-only setting (high-quality OCR + LLM) to approximate an upper bound when character recognition errors are minimized. Our evaluation framework provides two complementary protocols: (1) an objective protocol measuring field-level recall of structured items, and (2) an automated subjective protocol that uses an LLM-based judge to score factuality, interpretability, and reasoning quality under a fixed prompt. Using the objective metric as a reward signal, we also provide a lightweight GRPO-based alignment baseline for a mid-sized VLM, which improves field-level recall by up to 6%. Finally, we analyze practical limitations of OCR+LLM pipelines, including layout-related errors and additional system latency, showing the need for robust end-to-end vision-based medical report understanding. The dataset and evaluation resources are publicly available on https://huggingface.co/datasets/MedRepBench/MedRepBench.

Understanding the internal representations of large language models (LLMs) is a central challenge in interpretability research. Existing feature interpretability methods often rely on strong structural assumptions--such as linearity or sparsity--that may not hold in practice. In this work, we introduce InverseScope, an assumption-light and scalable framework for interpreting neural activations via input inversion. Given a target activation, InverseScope characterizes its encoded information by generating natural-language inputs that produce nearby activations, grounding abstract internal states in concrete language. To overcome the prohibitive cost of sampling in high-dimensional activation spaces, we propose a novel control-layer conditioning architecture that substantially improves sample efficiency compared to prior token-prepending approaches. We demonstrate that InverseScope reveals rich geometric structure in LLM representation spaces, including sentence-level linear analogies. The framework scales to state-of-the-art open-source models of up to 14B parameters and generalizes to out-of-distribution inputs, enabling systematic analysis of activation neighborhoods.

Mechanistic interpretability seeks to make verifiable statements about the internal behavior of large language models (LLMs). Many interpretability techniques struggle to scale with the increasing size and depth of architectures. Our solution to this is to introduce smaller models with structures that lend themselves to interpretability. In this work, we introduce the Stream Recursion Model (SRM), a modification of the Hierarchical Reasoning Model (HRM) designed to expose internal computational structure while remaining scalable. SRM organizes computation into multiple interacting latent streams that are updated through recursive refinement, enabling direct analysis of stream dynamics, causal contribution, and routing behavior. SRM achieves performance comparable to GPT-2 on a per-parameter basis. Our analysis reveals consistent and distinct behavior across streams, indicating structured specialization and interaction. These results suggest that SRM provides a practical architectural foundation for scalable mechanistic interpretability and opens up promising avenues for future research in both reasoning performance and interpretability.

Random forests (RFs) predict well but are opaque, whereas single decision trees are interpretable but unstable. Artificial representative trees (ARTs) were developed as interpretable surrogate models for RFs, but their use as standalone prediction models with uncertainty quantification has not been systematically investigated. We combine ARTs with leaf-wise Mondrian conformal predictive systems (CPS), enabling a single tree to provide continuous predictions, prediction intervals, and probabilities of exceeding arbitrary thresholds. We compared ARTs with CPS against decision trees with CPS and separate regression and probability trees across five simulation scenarios, 21 benchmark datasets, and a cross-sectional NHANES example data set. Repeated cross-validation assessed predictive performance, interpretability, and stability. ARTs with CPS yield compact, structurally stable trees with substantially more reproducible split-variable selection than decision trees across benchmark datasets and NHANES. Decision trees showed slightly better predictive performance and narrower prediction intervals, while coverage was broadly comparable. CPS-based trees generally achieved lower and less variable Brier scores than multi-model approaches. Combining ARTs with CPS therefore provides a single, interpretable, and stable model for continuous predictions and calibrated probabilities, balancing predictive performance with reproducibility and transparency in settings where stability and interpretability are essential.

Interpreter agents built on machine translation (MT) increasingly mediate live conversation between people who do not share a language, yet we still evaluate them with metrics built for isolated sentences, which measure fidelity rather than whether communication succeeds. We introduce a reusable three-layer checklist-and-judge framework that evaluates interpreter-mediated conversation across semantic, pragmatic, and cultural-social dimensions, covering the naturalness, intent, and social appropriateness that fidelity metrics leave unmeasured. It runs in both single-turn and interactive multi-turn settings, where simulated users reply to translated messages as the conversation unfolds and each turn is scored alongside the conversation as a whole. We extensively validate it through controlled perturbations, cross-judge comparisons, and human annotations. Our main single-turn benchmark evaluates 10 interpreter setups across Arabic, Bengali, Indonesian, and Korean from 5,624 OpenSubtitles-derived scenarios spanning 12 translation directions, and our multi-turn study covers all 6 language pairs in scripted and live modes. Results show a consistent decline from semantic to pragmatic and cultural-social success, while conventional MT metrics overlook failures among stronger interpreters, and prompt ablations show that scenario context, structured instructions, and cultural context improve communicative success, although gains vary across setups. Our work thus provides an evaluation framework and benchmark for interpreter agents in conversation, and highlights the importance of communicative success alongside existing translation metrics.

Genetic Programming and its variants, such as grammatical evolution, are widely used in Symbolic Regression to derive mathematical expressions from multivariate data. In addition to predictive accuracy, models are appreciated for their potential to provide interpretability, offering explicit equations that relate input variables to outcomes. However, achieving interpretability and plausibility remains challenging, as evolved models may be complex or scientifically inconsistent. In this study, we explore whether Large Language Models, can assist in improving the explainability of Symbolic Regression models generated by evolutionary computation methods. Building upon our previous work on estimating body fat percentage using grammar-based Genetic Programming , we investigate the use of LLMs as post-processing tools to analyze and rank evolved expressions according to their interpretability and medical plausibility. Four symbolic expressions are analysed by three LLMs over three repeated runs, and the resulting interpretations and rankings are assessed by a panel of three clinicians. Across the three LLMs, comparative model-ranking outputs received more favorable clinician assessments than isolated term-level interpretations. However, the LLMs also produced physiologically and mathematically questionable explanations, indicating that they are better suited to comparative auditing under expert oversight than to autonomous validation.\blfootnote{The present work is an extended version of a paper submitted into a journal.

As machine learned models increase in complexity and expressive power, features of simpler models, such as interpretability and control over the shape of the modeled function are lost. On the one edge of the spectrum we have simple linear models are transparent and possess good interpretability and explainability properties, but have a limited expressive power. On the other edge we have neural networks, that have expressive power that improves with scaling, but are mostly opaque. In this work we develop the \emph{spectral neuron} concept: a scalar model given by $f(\vx)=λ_k \left(A_0+\sum_{i=1}^n x_i A_i\right)$, with learned real symmetric matrices $A_0,\ldots,A_n$. The input enters the model through an affine matrix function, but the prediction is obtained by reading one of its eigenvalues. Thus, the model is nonlinear, but the source of nonlinearity is still mathematically explicit. This gives us a useful middle ground: the model can become more expressive as the matrix dimension grows, while retaining a degree of structural interpretability through the learned matrices. For example, extremal eigenvalues yield convex or concave functions, semidefinite constraints on the coefficient matrices impose monotonicity, and the associated eigenspaces characterize local feature sensitivity. We study the robustness, structural interpretability, and shape-control properties of this model family, and then test whether it can be learned and scaled in practice. We develop a systematic study of this model family, bringing together spectral results from several mathematical literatures to characterize its expressivity, robustness, interpretability, and shape-control properties.

Electronic Health Records (EHRs) are widely used for clinical risk prediction using machine learning. International Classification of Diseases (ICD) codes provide structured information about patient diagnoses, but representing them effectively remains challenging. Existing approaches often face a trade-off between predictive performance and interpretability: grouping-based representations are interpretable but may lose information, while embedding-based representations achieve strong predictive performance but are difficult to interpret. We propose Explainable Representation of Multiple ICD Codes (xMICD), a method for constructing low-dimensional patient representations from sets of ICD codes. xMICD combines clinically meaningful diagnostic groupings with similarity in a pre-trained ICD embedding space. Instead of using binary group membership, the method assigns codes to groups via similarity-based relative assignments, yielding features that reflect how closely a patient's diagnoses align with each clinical group. Experiments on large-scale EHR datasets demonstrate that xMICD achieves predictive performance comparable to embedding-based representations such as ICD2Vec across multiple clinical prediction tasks. At the same time, the resulting features remain clinically interpretable because each dimension corresponds to a recognizable diagnostic group. xMICD therefore provides a practical way to integrate embedding-based semantic relationships into interpretable clinical feature spaces for machine learning models.

Post-training quantization (PTQ) has become a practical solution for deploying deep learning models on resource-constrained edge devices by compressing high-precision floating-point weights into low-precision representations without requiring retraining. Past research has demonstrated that quantization largely preserves classification accuracy; however, whether it also preserves the model's internal reasoning remains an open question. This study presents a systematic evaluation on how static PTQ affects the interpretability / explainability of five widely used CNN architectures: VGG19, ResNet18, EfficientNet-B0, DenseNet161, and MobileNetV2 at INT8 and INT4 precision. We employ a dual interpretability framework that combines Grad-CAM for spatial attention analysis with LIME for input-level feature attribution, and systematically compare full-precision and quantized models on two binary classification datasets. Interpretability is evaluated using three complementary metrics: the Pearson correlation coefficient, structural similarity index, and top-20% IoU to capture distributional and structural variations in model explanations, supplemented by deletion/insertion faithfulness analysis. The results show that classification accuracy is not a reliable indicator of interpretability stability under reduced precision. DenseNet161 maintains strong feature consistency across both precision levels, whereas EfficientNet-B0, despite achieving competitive spatial attention and classification accuracy at INT8 precision, exhibits a substantial degradation in input-level feature attribution. These findings have direct implications for the trustworthy deployment of quantized models in applications with high interpretability requirements, demonstrating that architecture selection is as important as the quantization strategy.

Ultrasound image classification is essential for computer-aided diagnosis. However, current methods often neglect clinical priors, leading to poor generalization in challenging scenarios and a lack of interpretability that limits clinical adoption. To address these issues, we aim to develop a medical-prior module that can be seamlessly integrated into existing pipelines to enhance both diagnostic performance and interpretability. In this paper, we propose an attribute-guided dual-branch framework for ultrasound classification that introduces domain-agnostic medical attribute priors, improving generalization while offering interpretable evidence. Specifically, a baseline branch follows conventional architectures and predicts image categories via a fully connected classifier. An attribute-guided branch injects domain-agnostic attributes as priors and produces human-interpretable decision cues. Finally, an adaptive decision module fuses the two branches in a data-dependent manner to yield the final prediction. Experiments across diverse ultrasound classification tasks demonstrate that our approach can be integrated into multiple backbones and state-of-the-art methods with low overhead, consistently improving accuracy and interpretability. Code is available at: https://github.com/zhaobo253-crypto/AttrGuide.

Given the widespread prevalence of depression and its consequential impact on individuals and society, it is crucial to obtain objective measures for early diagnosis and intervention. As a multidisciplinary topic, these objective measures should be interpretable and accessible to health care professionals, ensuring effective collaboration and treatment planning in the realm of mental health care. Even though current automated depression diagnosis approaches improved over the last decade, a critical gap exists as they often lack affect-specificity and interpretability, limiting their practical application and potential impact on mental health care. In particular, interpretability from temporal activities from videos when deep models are used is not fully explored. In this study, we present a novel framework for analyzing Deep Neural Networks' decisions when trained on facial videos, specifically focusing on automatic depression severity diagnosis. By fine-tuning Deep Convolutional Neural Networks (DCNN) pre-trained on Action Recognition datasets on depression severity facial videos from AVEC depression dataset, our framework is able to interpret the model's saliency maps by examining face regions and temporal expression semantics. Our approach generates both visual and quantitative explanations for the model's decisions, providing greater insight into its reasoning. In addition to this interpretability, our video-based modeling has improved upon previous single-face benchmarks for visual depression diagnosis, resulting in enhanced predictive performance. Overall, our work demonstrates the successful development of a framework capable of generating hypotheses from a facial model's decisions while simultaneously improving depression's predictive capabilities.

Autonomous driving has shifted towards end-to-end policy learning, where reliable, interpretable policy evaluation is a fundamental challenge as driving quality is highly context-dependent. Commonly used rule-based driving metrics like EPDMS are interpretable but lack context-awareness, while recent VLMbased evaluations are context-aware but limited by ambiguous VLM outputs and weak physical grounding. To evaluate driving in a manner that is both interpretable and context-aware, we introduce DriveJudge. DriveJudge is a driving evaluation agent that combines rule-grounded evaluation with Vision-Language Model (VLM) reasoning and selectively invokes physically-grounded deterministic rule functions after interpreting the environmental context. To train and evaluate DriveJudge, we curate a large-scale dataset of 33,577 challenging driving samples with human annotations on whether the driving behavior is reasonable in the given scenario. With this dataset, we address the underexplored problem of driving metric evaluation, and introduce two human-aligned benchmark tasks: Driving Quality Classification and Trajectory Preference Selection. DriveJudge outperforms EPDMS for driving quality classification by 21.23 AUC, and the recent VLM-based DriveCritic for trajectory preference selection by 6.5%, setting a new standard for interpretable and precise driving evaluation.

Learning systems based on IF-THEN rule representations readily offer interpretability, making them a crucial focus in contemporary AI research. A key objective for such rule sets is to achieve both high discriminative power and interpretability. While existing state-of-the-art algorithms implicitly prioritize predictive accuracy, they often fall short on one or more quality metrics that ensure interpretability, such as coverage and parsimony of rule sets. Motivated by this, this paper propose the development of CDPR, which aims to create highly accurate and interpretable rule sets for classification problems. To the best of our knowledge, this represents the first attempt to establish such an approach. In this study, we introduce two algorithms rooted in submodular maximization, which not only provide provable guarantees on coverage but also yield rule sets that are both discriminative and parsimonious. We empirically demonstrate that rule sets learned through our approaches achieve higher accuracy and interpretability and has more than a 2.5-fold improvement in average coverage rates when compared to the next best algorithm.

Information lattice learning (ILL) learns interpretable rules of a signal by alternately projecting the signal onto a partition lattice that encodes a hierarchy of abstractions and lifting selected rules back to the signal domain. When the signal is a probability mass function, we show the probabilistic rules learned by ILL admit a natural probabilistic graphical model (PGM) interpretation and develop this interpretation in detail. A partition in ILL induces a deterministic quotient variable, and a rule is the marginal law of that quotient variable. A rule set is therefore a collection of marginal constraints over interpretable abstractions. General lifting is the feasible family of all joint distributions satisfying those constraints, while special lifting chooses a maximum-ignorance reconstruction, implemented in ILL by an L2 uniformity principle closely related to maximum entropy. Under a Shannon-entropy lifting, the same constraints yield a log-linear factor graph whose factors are indexed by learned abstractions. The information lattice itself, however, is not a Bayesian network: its edges encode refinement and coarsening of abstractions, not conditional dependence. Thus ILL is best viewed as structure learning for interpretable constraint-based factor graphs over quotient variables. This view clarifies how ILL relates to graphical models and maximum entropy models, while suggesting new directions for inference, identifiability, and hybrid symbolic-probabilistic learning.