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Achieving cultural alignment in Large Language Models (LLMs) increasingly depends on synthetic data generation. For such synthesis, the most vital initial step is seed curation; however, current methods lack quantifiable standards for selecting these seeds. Existing approaches rely on unscalable manual curation or bias-prone LLM extraction, treating cultural specificity as an abstract concept rather than a measurable signal. In this paper, we address this "quantification gap" by proposing C-Mining, an unsupervised framework that transforms the discovery of cultural seeds from a subjective selection process into a computable data mining formulation. Our approach exploits a novel geometric insight, leveraging the cross-lingual misalignment of cultural concepts within pre-trained embedding spaces as a quantifiable discovery signal. By systematically identifying these regions characterized by pronounced linguistic exclusivity and geometric isolation, while actively filtering out noise, C-Mining automatically extracts high-fidelity Culture Points (CPs) from raw multilingual corpora without reliance on human or LLM supervision, reducing preparation costs by more than 150-fold. We further leverage the mined knowledge to steer the synthesis of diverse instruction-tuning datasets. Extensive experiments demonstrate that this seed-centric approach significantly enhances cultural understanding and reasoning capabilities, achieving a +6.03 point improvement on CulturalBench-Hard and surpassing state-of-the-art baselines, providing a scalable, quantifiable solution for high-quality cultural data synthesis.

Evaluating AI tutor responses requires more than factual correctness: tutors must identify mistakes, locate errors, provide guidance, and offer actionable next steps. We present GRADE, a systematic study of open-source models for pedagogical ability assessment in student-tutor dialogues. Building on the BEA 2025 TutorMind setting, we evaluate 120 configurations across five language models, zero-shot inference, LoRA fine-tuning, synthetic augmentation, CoT+Reasoning, and single-task versus multitask formulations. Gemma3-12B performs best for single-task evaluation, while Gemma3-27B in 8-bit precision is more reliable for multitask prediction. We find that augmentation helps models that struggle with the original data, verification adds limited gains despite higher cost, and CoT+Reasoning is more useful for synthetic data generation than direct classification. We further show that LoRA fine-tuning on structured classification objectives interferes with instruction-following behavior under thinking mode, redirecting generation away from the required evaluation format. Carbon analysis shows that model choice and reasoning mode substantially affect emissions. Overall, GRADE shows that carefully selected open-source LoRA pipelines can match or surpass proprietary and ensemble-based systems on key pedagogical dimensions, with code and data available at https://github.com/pvbgeek/GRADE.

Diffusion generative models have demonstrated immense potential for synthetic medical image generation. However, these models often struggle to capture complex morphological characteristics of heterogeneous tumors with irregular boundaries, limiting their utility for downstream clinical tasks such as segmentation. This limitation stems from the standard denoising objective: minimizing a per-pixel error, which smooths high-variance irregular structures characteristic of tumors. To address this, we propose finetuning these generative models with Fréchet Distance loss (FD-loss). FD-loss aligns the first and second order feature statistics of real and generated images in a pretrained encoder space, encouraging the generator to capture complex structural variations characteristic of heterogeneous tumors. We integrate FD-loss across diverse architectural settings, using both natural- and medical-image encoders on multiple liver and brain cancer datasets spanning CT and MRI modalities. Downstream segmentation networks trained on our FD-regularized synthetic data consistently achieve superior performance, improving tumor DSC by >$$5\% over unregularized synthetic augmentation alone. Qualitative analysis suggests these gains are associated with more faithful tumor synthesis and fewer segmentation hallucinations. Our results show FD-loss as an effective regularizer for medical image generative models to improve clinical workflows.

Generative models in finance face the dual challenge of producing realistic data while satisfying strict regulatory and economic objectives, a requirement that standard tabular diffusion models cannot provide. To address this difficulty, we introduce Constrained Tabular Diffusion for Finance (CTDF), a novel integration of sampling-time feasibility operations with mixed-type tabular diffusion in financial applications. By incorporating a training-free feasibility operator into the reverse-diffusion sampling loop, CTDF enforces hard constraints for applications such as simulation, legal compliance, and extrapolation. Extensive experiments on large-scale financial datasets demonstrate zero constraint violations and improvement in scarce data utility. CTDF establishes a robust method for generating trustworthy and compliant synthetic data, opening new avenues for rigorous generative modeling and analysis in the financial domain.

Sensors are critical components of modern intelligent devices. The proliferation of the Internet of Things (IoT) and wearable mobile devices has enabled the integration of such sensors to monitor the environment and enable users to take predictive actions. Human activity recognition (HAR) is a popular application in which Inertial Measurement Unit (IMU)-based sensors, such as accelerometers and gyroscopes, are used to provide insights into health, training, and medical diagnosis. However, the accuracy of such a model is hindered by the lack of data. The diffusion model-based technique has proven successful in generating synthetic data for training HAR models. In this paper, we propose a backdoor training technique, IMU-DM-CLIP, that leverages a diffusion model to enable trigger-based attacks on HAR models. Our empirical analysis shows that the attack is successful even with a very small backdoor injection rate of 10% and 10% of the data guided for the diffusion model.

Background: External validation is essential for assessing the transportability of predictive models. However, its interpretation is often confounded by differences between external and development populations. This study introduces a framework to distinguish model deficiencies from case-mix effects. Method: We propose a framework that quantifies each external patient's similarity to the development data and measures performance in subgroups with varying levels of alignment to the development distribution. We use generative models, specifically autoencoders, to estimate similarity, offering a more flexible alternative to traditional linear approaches and enabling validation without sharing the original development data. The utility of autoencoder-based similarity measure is demonstrated using synthetic data, and the framework's application is illustrated using data from the Netherlands Heart Registration (NHR) to predict mortality after transcatheter aortic valve implantation. Results: Our framework revealed substantial variation in model performance across similarity-defined subgroups, differences that remain hidden under conventional external validation yet can meaningfully alter conclusions. In several settings, conventional external validation suggested poor overall performance. However, after accounting for differences in patient characteristics, for some sub-groups, the model performance was consistent with internal validation results. Conversely, apparently acceptable overall performance could mask clinically relevant performance deficits in specific subgroups. Conclusion: The proposed framework enhances the interpretability of external validation by linking model performance to population alignment with the development data. This provides a more principled basis for deciding whether a model is transportable and to which patients it can be safely applied.

While recent self-training approaches have reduced reliance on human-labeled data for aligning LLMs, they still face critical limitations: (i) sensitivity to synthetic data quality, leading to instability and bias amplification in iterative training; (ii) ineffective optimization due to a diminishing gap between positive and negative responses over successive training iterations. In this paper, we propose Team-based self-Play with dual Adaptive Weighting (TPAW), a novel self-play algorithm designed to improve alignment in a fully self-supervised setting. TPAW adopts a team-based framework in which the current policy model both collaborates with and competes against historical checkpoints, promoting more stable and efficient optimization. To further enhance learning, we design two adaptive weighting mechanisms: (i) a response reweighting scheme that adjusts the importance of target responses, and (ii) a player weighting strategy that dynamically modulates each team member's contribution during training. Initialized from a SFT model, TPAW iteratively refines alignment without requiring additional human supervision. Experimental results demonstrate that TPAW consistently outperforms existing baselines across various base models and LLM benchmarks. Our code is publicly available at https://github.com/lab-klc/TPAW.

Current large language models reason in isolation. Although it is common to sample multiple reasoning paths in parallel, these trajectories do not interact, and often fail in the same redundant ways. We introduce LACE, a framework that transforms reasoning from a collection of independent trials into a coordinated, parallel process. By repurposing the model architecture to enable cross-thread attention, LACE allows concurrent reasoning paths to share intermediate insights and correct one another during inference. A central challenge is the absence of natural training data that exhibits such collaborative behavior. We address this gap with a synthetic data pipeline that explicitly teaches models to communicate and error-correct across threads. Experiments show that this unified exploration substantially outperforms standard parallel search, improving reasoning accuracy by over 7 points. Our results suggest that large language models can be more effective when parallel reasoning paths are allowed to interact.

Gesture recognition research, unlike NLP, continues to face acute data scarcity, with progress constrained by the need for costly human recordings or image processing approaches that cannot generate authentic variability in the gestures themselves. Recent advancements in image-to-video foundation models have enabled the generation of photorealistic, semantically rich videos guided by natural language. These capabilities open up new possibilities for creating effort-free synthetic data, raising the critical question of whether video Generative AI models can augment and complement traditional human-generated gesture data. In this paper, we introduce and analyze prompt-based video generation to construct a realistic deictic gestures dataset and rigorously evaluate its effectiveness for downstream tasks. We propose a data generation pipeline that produces deictic gestures from a small number of reference samples collected from human participants, providing an accessible approach that can be leveraged both within and beyond the machine learning community. Our results demonstrate that the synthetic gestures not only align closely with real ones in terms of visual fidelity but also introduce meaningful variability and novelty that enrich the original data, further supported by superior performance of various deep models using a mixed dataset. These findings highlight that image-to-video techniques, even in their early stages, offer a powerful zero-shot approach to gesture synthesis with clear benefits for downstream tasks.

Multi-view reasoning in coronary X-ray angiography is inherently a cross-projection geometric problem, yet automated report generation in this setting remains largely unexplored. The 3D vascular topology leads to projection-dependent branch overlap and foreshortening, rendering single-view modeling fundamentally incomplete and unstable for lesion localization and stenosis grading. Although multi-view fusion appears promising, learning anatomically consistent fusion from real angiograms is impeded by a critical limitation: cross-view alignment is unobservable and cannot be explicitly supervised. Consequently, conventional fusion relies on implicit correlations rather than verified anatomical correspondence. We address this by reformulating multi-view stenosis reporting as an alignment-constrained aggregation problem. A controllable synthetic angiography generation strategy is introduced to expose geometry-derived patch-level correspondence supervision unavailable in real data. An anatomy-correspondence module learns cross-view correspondence matrices that explicitly align auxiliary features within the main-view coordinate space prior to fusion, thereby constraining evidence aggregation to anatomically consistent regions. Experiments on synthetic data and zero-shot transfer to real angiograms show that this alignment-constrained design improves correspondence consistency and structured stenosis reporting compared to single-view modeling and conventional multi-view fusion methods. The code will be publicly available upon publication.

AI-based scientific automation is increasingly possible by using agents to generate hypotheses, design experiments, and analyze data. Data collection is a major bottleneck in this pipeline, however. Psychology, and computational cognitive science in particular, is well-positioned to benefit from AI experimentation because theories are often represented as code and crowdsourcing platforms enable programmatic human data collection at scale. Here, we apply automated discovery techniques to the project of generating theories in computational cognitive science, with an agent-based system collecting human data independently through crowdsourced survey experiments. As a testbed, we use a classic case study from cognitive psychology: judging which sequences of coin flips seem subjectively more random. Our system, auto-psych, uses nested agent-based discovery loops to generate explanatory theories of human behavior. The inner loop conjectures, fits, and critiques probabilistic cognitive models; the outer loop designs experiments to test these models, launches them online, and analyzes the data. This system can quickly and reliably recover ground-truth theories from synthetic data via systematic experimentation, but the nested structure is critical to model performance. Further, in three independent sequences of human experiments, the system finds theories that fit the data better than theories generated from the scientific literature. This work thus demonstrates the feasibility of automated data collection and theory discovery in computational cognitive science.

Finding the source of failures, known as Root Cause Analysis (RCA), is essential for identifying the root causes of anomalies and maintaining the reliability of complex systems. While causal theory has advanced data-driven RCA, existing frameworks assume causal sufficiency, failing to account for the unobserved latent variables prevalent in real-world environments. To address this gap, we propose PAG-RCA. This framework models system failures as parametric interventions over Partial Ancestral Graphs (PAGs) to perform RCA in the presence of latent variables. We use standard causal identification algorithms to find the source of failures by quantifying causal effects over the PAG. When an effect is identifiable, candidate root causes are ranked based on their exact intervention effects. When effects are structurally unidentifiable, our framework (for the first time in the RCA literature) integrates partial identification to evaluate and score candidates using analytical causal bounds. By integrating latent variables and partial identification at once our framework ensures robust RCA even under data scarcity and latent-variable scenarios where traditional methods degrade. Evaluations on synthetic data, microservice anomaly benchmarks and power-grid cascading failures demonstrate that PAG-RCA consistently outperforms state-of-the-art data-driven baselines. By improving data-driven RCA performance under data scarcity, this methodology advances reliable automated diagnostics in partially observable complex networks.

Despite the fact that experimental neural scaling laws have substantially guided empirical progress in large-scale machine learning, no existing theory can quantitatively predict the exponents of these important laws for any modern LLM trained on any natural language dataset. We provide the first such theory in the case of data-limited scaling laws. We isolate two key statistical properties of language that alone can predict neural scaling exponents: (i) the decay of pairwise token correlations with time separation between token pairs, and (ii) the decay of the next-token conditional entropy with the length of the conditioning context. We further derive a simple formula in terms of these statistics that predicts data-limited neural scaling exponents from first principles without any free parameters or synthetic data models. Our theory exhibits a remarkable match with experimentally measured neural scaling laws obtained from training GPT-2 and LLaMA style models from scratch on two qualitatively different benchmarks, TinyStories and WikiText.

In visual localization, Absolute Pose Regression (APR) enables real-time 6-DoF camera pose inference from single images, yet critically depends on fine-tuning data quality and coverage. While recent methods leverage 3D Gaussian Splatting (3DGS) for novel view synthesis-based data augmentation, random sampling generates redundant views and noisy samples from poorly reconstructed regions. To mitigate this research gap, we propose PoseCompass, an intelligent pose selection pipeline for 3DGS-based APR. PoseCompass formulates synthetic pose selection and derives a value-based pose ranking mechanism to identify informative poses. The ranking integrates three dimensions: Localization Difficulty, favoring challenging regions; Coverage Novelty, exploring under-sampled areas; and Rendering Observability, filtering artifacts and noise. PoseCompass then generates trajectory-constrained candidates, selects the top-K ranked poses, and synthesizes views using 3DGS with lightweight diffusion-based alignment. Finally, the pose regressor is fine-tuned on mixed real and synthetic data. We evaluate PoseCompass on 7-Scenes, where it reduces adaptation time from 15.2 to 5.1 minutes, a 3x speedup, while cutting median pose errors by 53.8 percent and significantly outperforming random baselines.

Advances in language modeling have been driven by scaling pretraining on ever more data. Yet, the training data is still largely curated on the model's behalf. A more general approach to pretraining would let the model learn to generate the data most useful for its own improvement. This would provide an effectively unbounded source of training data, limited by compute rather than human knowledge. We introduce Self-Play Pretraining with Zero Data, an initial proof-of-concept towards realizing this vision. Our procedure casts synthetic data generation as a search over the space of all computable structure, taking inspiration from Solomonoff induction. Starting from random initialization, two models learn in tandem: a generator proposes programs interpreted by a universal Turing machine, generating byte sequences, while a learner autoregressively predicts these byte sequences. The learner is trained with standard cross-entropy, while the generator is trained with reinforcement learning to produce sequences at the frontier of the learner's capabilities, yielding an adaptive curriculum. A universal Turing machine gives us a search space over all computable data-generating processes, imposing little domain-specific structure, and self-play searches over this space for useful training data. We test whether zero-shot performance on natural data improves predictably with self-play compute; this is a clean test of transfer since neither generator nor learner is trained on natural data. Across several natural datasets, zero-shot loss exhibits predictable scaling in compute. The models also exhibit in-context learning, and discover recognizable mathematical sequences during training.

Engineered Skeletal Muscle Tissues (ESMs) have become a key structure for biomedical disease modeling and pharmacological screening, yet their functional characterization often relies on simplistic metrics like peak force, discarding critical kinetic information. This is partially due to the high level of mathematical complexity which mechanistic models introduce to capture these dynamics. Hence, exactly the complexity prevents scalable application and widespread adaptation in the field. Here we present a Physics-Flavored Neural Network (PFNN) that automates the kinetic phenotyping of ESMs. Our architecture integrates a stretched-exponential physical model into a CNN-Transformer, enabling the extraction of physically meaningful parameters directly from force-time profiles. To address the scarcity of labeled biological data, we employ a hybrid training paradigm: the model develops a "physical intuition" on synthetic data before undergoing unsupervised self-alignment on unlabeled real-world measurements. Our results demonstrate that this physics-flavored approach achieves high-fidelity parameterization across diverse contractile phenotypes and cell lines, including Duchenne Muscular Dystrophy models. Our scalable, self-improving pipeline bridges the gap between idealized biophysics and noisy \emph{in vitro} data, providing a robust tool for high-throughput biophysical research.

Real-world tasks often lack large labeled datasets, motivating extensive work on learning in low-data regimes. However, existing approaches such as few-shot prompting, instruction tuning, and synthetic data generation, continue to treat labeled or pseudo-labeled data as the primary learning signal. In contrast, human practitioners acquire expertise through repeated, self-directed interaction with the open web, progressively refining both domain knowledge and search strategies. We propose MEMENTO, a framework that treats the web as a learning signal rather than a stateless retrieval interface. MEMENTO operates at two levels: within each session, it conducts iterative web exploration via an Adaptive Exploration Tree (AET) that decomposes tasks into evolving questions and reflects on intermediate findings; across sessions, it accumulates experience through dual-channel memory, separating declarative knowledge (facts) from procedural knowledge (search strategies). This design enables agents to learn reusable research strategies and domain expertise from trajectories of web interaction without additional model training. We evaluate MEMENTO on two low-data professional domains: sales automation and legal research. Our empirical results show consistent improvements in performance over ReAct based baselines (+25.6% on sales automation and 36.5% on legal research), demonstrating that the web can serve as a scalable learning source for acquiring task-specific expertise in data-scarce settings.

Adapting large language models (LLMs) to a targeted task efficiently and effectively remains a fundamental challenge. Such adaptation often requires iteratively improving the model toward a targeted task, yet collecting high-quality human-labeled data to support this process is costly and difficult to scale. As a result, synthetic data generation has emerged as a flexible and scalable alternative. One straightforward approach is through an iterative generation-training loop, where candidate data are synthesized through an external generator, the model is updated using these data and the process is repeated over iterations. However, generated samples can be noisy, highly redundant, or even misaligned with the targeted task distribution. Training indiscriminately on such data can dilute useful learning signals and even degrade model performance. To address this, we introduce a refined paradigm, namely an iterative generation-selection-training loop, which incorporates a selection step prior to model updates. Building on this paradigm, we propose EvoSelect, a data-efficient framework to evolve LLM effectively. Given candidate samples produced by the data generator, EvoSelect selects training data by jointly modeling targeted task alignment and diversity. We estimate task relevance through optimal transport with proxy gradient representations, which quantifies how well candidate samples align with the targeted task distribution. To mitigate redundancy, we incorporate a diversification mechanism that promotes coverage of complementary training samples. By interleaving alignment and diversification, EvoSelect enables progressive LLM evolution toward targeted tasks. Extensive experiments on various benchmarks demonstrate that with either weak or strong data generators, EvoSelect consistently improves adaptation efficacy over existing data selection methods.

Unified multimodal generation architectures that jointly produce text and images have recently emerged as a promising direction for text-to-image (T2I) synthesis. However, many existing systems rely on explicit modality switching, generating reasoning text before switching manually to image generation. This separate, sequential inference process limits cross-modal coupling and prohibits automatic multimodal generation. This work explores post-training to achieve fully unified text-image generation, where a model autonomously transitions from textual reasoning to visual synthesis within a single inference process. We study this on BAGEL, a 14B mixture-of-transformers model that pairs autoregressive text generation with flow-matching image synthesis. We examine the impact of joint text-image generation on T2I performance and the relative importance of each modality during post-training. We additionally explore different post-training data strategies, showing that a targeted dataset addressing specific limitations achieves superior results compared to broad image-caption corpora or benchmark-aligned data. Using offline, reward-weighted post-training with fully self-generated synthetic data, our approach enables improvements in multimodal image generation across four diverse, independent T2I benchmarks, demonstrating the effectiveness of reward-weighting both modalities and strategically designed post-training data.

Structured data is widely used in domains such as healthcare, finance, and scientific data management. Recent studies on structured data foundation models (SFMs) aim to support data analysis and mining tasks over such data, but still face scalability and generalization challenges when applied to real-world enterprise databases. First, many SFMs rely on full self-attention, which introduces an O(N^2) computational bottleneck and limits the number of tuples that can be processed jointly. Second, directly replacing attention with linear-complexity sequence models may conflict with the permutation-invariant nature of structured data, introducing artificial order bias and degrading representation quality. Moreover, models trained only on synthetic data may struggle to generalize to the heavy-tailed and heterogeneous distributions commonly found in real-world databases. To address these challenges, we propose FEAT, a linear-complexity foundation model for extremely large structured data. FEAT replaces quadratic attention with a multi-layer dual-axis encoding architecture. It integrates an adaptive-fusion bidirectional state-space model (AFBM) with convolutional gated linear attention (Conv-GLA), enabling cross-tuple contextualization in O(N) time while supporting permutation-invariant representation learning. To improve robustness under real-world data skewness, FEAT further adopts a hybrid structural causal pre-training pipeline with a robust reconstruction objective. Experiments on 12 real-world database benchmarks show that FEAT consistently outperforms representative SFMs on zero-shot tasks and scales linearly with structured-data sample length, achieving up to 50x faster inference latency.

We present our solution to the LUMPI track of the UCF UrbanTwin Sim2Real LiDAR Challenge at the 6th DriveX Workshop, ECCV 2026. The detector must be trained only on synthetic data and is evaluated on 50 held-out real LiDAR frames; a separate 50-frame synthetic submission is evaluated for point-cloud realism. Our method addresses the Sim2Real gap at three levels. First, we align synthetic scans to the 50k-point test density and build a 30k-record training pool using UT-LUMPI geometry, RangeLDM-based sampling diversification, rare-class copy-paste, and pedestrian-oriented augmentation. Second, complementary DSVT detectors and Car/Bus PointPillars specialists are trained under the same synthetic-only constraint. Third, predictions are integrated by class-aware routing, asymmetric agreement fusion, constrained residual-recall supplementation, class-coverage auditing, and selective box-size calibration. The realism branch is optimized independently with radial-density matching, weak affine calibration, and calibrated set mixing. The final submission obtains a Combined Score of 0.4692, a Detection Score of 0.1797, a Realism Score of 0.9035, and 3D mAP@0.5 of 0.1258.

Dataset condensation aims to construct compact datasets from real data via synthesis or selection. However, existing approaches are ill-suited for diffusion model training: synthetic data generation often yields low-fidelity samples unsuitable for authentic modeling, while real subset selection typically fails to preserve the distributional geometry required by diffusion likelihood objectives. To address this, we propose to reformulate real subset selection as a geometry-aware distribution alignment problem. By incorporating one-sided partial optimal transport, our method selectively aligns a compact subset with the full data distribution while allowing unmatched mass in low-density regions, ensuring the preserved geometric structure necessary for effective diffusion model training. To further ensure distributional fidelity, we complement geometric alignment with lightweight feature-statistics and semantic consistency regularization. An efficient two-stage discrete optimization strategy is proposed to achieve this alignment objective. Extensive experiments across diffusion variants, subset sizes, image resolutions, and training rounds show that our method achieves superior fidelity and distributional coverage in diffusion model training. Codes are available at https://github.com/2018cx/GADC.

Critical transitions - abrupt, often irreversible changes in system dynamics - arise across human and natural systems, often with catastrophic consequences. Real-world observations of such shifts remain scarce, preventing the development of reliable early warning systems. Conventional statistical and spectral indicators, such as increasing variance, tend to fail under realistic conditions of limited data and correlated noise, whereas existing deep learning classifiers do not extrapolate beyond their training data distribution. In this work, we introduce TipPFN, an in-context learning (ICL) framework that uses a prior-data fitted network to infer a system's proximity to a critical transition. Trained on our novel synthetic data generator, which is based on canonical bifurcation scenarios coupled to diverse, randomized stochastic dynamics, TipPFN flexibly capitalizes on contexts of various sizes, complexity and dimensionalities. We demonstrate robust, state-of-the-art early detection of critical transitions in previously unseen tipping regimes, sim-to-real examples, and real-world observations in both ICL and zero-shot settings.

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image translation, which can distort tissue structures and compromise model accuracy. In this work, we propose a semi-supervised domain adaptation (SSDA) framework that utilizes a latent diffusion model trained on unlabeled data from both the source and target domains to generate morphology-preserving and target-aware synthetic images. By conditioning the diffusion model on foundation model features, cohort identity, and tissue preparation method, we preserve tissue structure in the source domain while introducing target-domain appearance characteristics. The target-aware synthetic images, combined with real, labeled images from the source cohort, are subsequently used to train a downstream classifier, which is then tested on the target cohort. The effectiveness of the proposed SSDA framework is demonstrated on the task of lung adenocarcinoma prognostication. The proposed augmentation yielded substantially better performance on the held-out test set from the target cohort, without degrading source-cohort performance. The approach improved the weighted F1 score on the target-cohort held-out test set from 0.611 to 0.706 and the macro F1 score from 0.641 to 0.716. Our results demonstrate that target-aware diffusion-based synthetic data augmentation provides a promising and effective approach for improving domain generalization in computational pathology.

In recent years, autonomous driving has significantly in creased the demand for high-quality data to train 2D and 3D perception models for safety-critical scenarios. Real world datasets struggle to meet this demand as require ments continuously evolve and large-scale annotated data collection remains costly and time-consuming making syn thetic data a scalable, practical and controllable alterna tive. Pedestrian detection is among the most safety-critical tasks in autonomous driving. In this paper, we propose a simple yet effective method for scaling variability in 3D pedestrian assets for synthetic scene generation. Starting from a single 3D base asset, we generate multiple distinct pedestrian instances by synthesizing diverse facial textures and identity-level appearance variations using StyleGAN2 and automatically mapping them onto 3D meshes. This ap proach enables scalable appearance-level asset diversifica tion without requiring the design of new geometries for each instance. Using the assets, we construct synthetic datasets and study the impact of mixing real and synthetic data for RGB-based object detection. Through complementary ex periments, we analyze geometry-driven distribution shifts in point cloud perception for 3D object detection. Our findings demonstrate that controlled synthetic diversifica tion improves robustness in 2D detection while revealing the sensitivity of 3D perception models to geometric domain gaps. Overall, this work highlights how generative AI en ables scalable, simulation-ready pedestrian diversification through controlled facial texture synthesis, along with the benefits and limitations of cross-domain training strategies in autonomous driving pipelines.

Passive acoustic sensing is an attractive modality for counter-unmanned aerial system (counter-UAS) defence: it is covert, low-cost, and effective against drones with small radar cross-sections or minimal radio emissions. We present EchoHawk, an open and fully reproducible reference pipeline that detects a drone from its rotor harmonics, estimates its blade-passing frequency, and localises it with a microphone array via classical wideband beamforming (delay-and-sum, MVDR, MUSIC) and time-delay processing (GCC-PHAT, SRP-PHAT), followed by temporal tracking. We evaluate the system on a physically transparent synthetic benchmark that pits drones against hard low-frequency harmonic confusers, such as ground vehicles, and on real recorded audio. Our central methodological contribution is a documented case of session-level data leakage in a widely used public dataset: because its recordings are pre-segmented into short clips, naive clip-level splits place adjacent slices of the same continuous recording in both training and test sets, inflating reported performance. Enforcing recording-session-grouped cross-validation reduces, for example, a random-forest baseline's detection probability at a 1% false-alarm rate from 0.796 to 0.745, yielding honest numbers. All code, figures, and a synthetic data generator are released so that every result runs without any download.

Learning disentangled representations is a key requirement for developing versatile, general-purpose, and sustainable models in multi-modal wearable computing. However, existing approaches do not operate as full-stack wearable processors, i.e., they do not simultaneously address task-specific classification performance, disentangled and interpretable representation learning, fusion, and generative modeling of highly heterogeneous multi-modal time series. To address this gap, we introduce Omni-modal Variational Decomposition Autoencoders (OmniDecVAEs), a framework that efficiently learns multi-purpose representations in a unified and scalable manner from arbitrarily many modalities. OmniDecVAEs extend DecVAEs by learning modality-conditioned time-frequency latent subspaces through a multi-view self-supervised decomposition loss and a shared asymmetric autoencoder (AE) architecture. Results on a challenging omni-modal human activity recognition (HAR) setting with up to thirty modalities, demonstrate the ability of OmniDecVAEs to learn full-stack wearable representations. When compared to transformer-based and VAE-based methods, OmniDecVAEs full-stack disentangled representation properties lead to accuracy improvements of 1.01% and 6.75% in activity and identity recognition, respectively. Furthermore, OmniDecVAEs synthesize realistic omni-modal time-frequency data that manifest with enhanced reconstructions (mean absolute error improves by 76.84%) and distributional similarity between real and synthetic data (maximum mean discrepancy improves by 13.85%). Our results highlight OmniDecVAEs potential as a lightweight model suitable for intelligent edge wearables and clinical healthcare, unifying processing requirements and abilities in a single model, through its enhanced representational capacity, modality-invariant spatial complexity (4.1M parameters), and real-time latency.

In astronomical imaging, the low photon count of exposures necessitates extensive post-processing steps, including contamination removal and denoising. This paper evaluates deep-learning denoising methods that can be trained without clean ground-truth images and assesses their utility for detection11 oriented analysis of astronomical data. We adapt and compare Noise2Noise, Stein's Unbiased Risk Estimator, and blind-spot-based methods using synthetic data and real observations from the Hubble Space Telescope (HST) and the Canada-France-Hawaii Telescope (CFHT). Performance is evaluated using object-detection metrics, including correct detection rate and false alarm rate, together with image-based metrics and pixel-distribution diagnostics. The results show that these methods can improve faint-source detectability relative to the original noisy images, with encouraging gains on HST data after domain-consistent initialization, while transfer to CFHT data is more limited, highlighting the importance of instrument/domain similarity for unsupervised adaptation.

AIGC has shown remarkable success in CV and NLP, and has recently demonstrated promising potential in the wireless domain. However, significant data imbalance exists across RF modalities, with abundant WiFi data but scarce mmWave and RFID data due to high acquisition cost. This makes it difficult to train high-quality generative models for these data-scarce modalities. In this work, we propose RF-CMG, a diffusion-based cross-modal generative method that leverages data-rich WiFi signals to synthesize high-fidelity RF data for scarce modalities including mmWave and RFID. The key insight of RF-CMG is to decouple cross-modal generation into high-frequency guidance and low-frequency constraint, which respectively learn high-frequency distribution from limited target modality data and preserve the underlying physical structure via low-frequency constraints during generation. On this basis, we introduce a Modality-Guided Embedding (MGE) module to steer the reverse diffusion trajectory toward the target high-frequency distribution, and a Low-Frequency Modality Consistency (LFMC) module to progressively enforce low-frequency constraints to suppress the accumulation of source-modality structural biases during inference, enabling high-quality target-modality generation. Performance comparison with several prevalent generative models demonstrates that RF-CMG achieves superior performance in synthesizing RFID and mmWave signals. We further showcase the effectiveness of the data generated by RF-CMG in gesture recognition tasks, and analyze the impact of the proportion of synthetic data on downstream performance.

Neonatal jaundice (hyperbilirubinemia) is one of the most common conditions affecting newborns worldwide, with India alone recording roughly 15 million cases per year. Early detection is critical, yet standard diagnosis requires blood tests that are often impractical in rural clinics where laboratory facilities are limited. This paper presents NeoJaundice-AI, a smartphone-based screening system that uses photographs of a baby's skin and sclera (eye white) to estimate jaundice severity and predict serum bilirubin levels in under three seconds without requiring internet connectivity. The proposed system is built on a dual-branch EfficientNet-B0 architecture that independently processes skin and sclera images. Deep features are fused with handcrafted YCbCr color statistics to jointly perform four-class severity classification and continuous bilirubin regression. A key contribution is a synthetic jaundice generation method that simulates bilirubin-induced yellowing through controlled YCbCr channel modifications on normal neonatal skin images. This approach addresses data scarcity, particularly for severe jaundice cases and darker Indian skin tones (Fitzpatrick Types IV to VI). In addition, a skin-tone normalization module improves prediction consistency across diverse neonatal complexions. Experimental results demonstrate an overall classification accuracy of 91.8 percent, a clinical sensitivity of 93.5 percent, and a bilirubin mean absolute error of 1.4 mg/dL. After INT8 quantization and ONNX conversion, the model size is reduced to 8.3 MB while maintaining inference times below three seconds on standard Android devices. To the best of our knowledge, this is the first India-focused neonatal jaundice AI system that combines multimodal image fusion, skin-tone adaptation, synthetic data augmentation, and fully offline mobile deployment within a single framework.