Interpretable ML

Understanding and monitoring human behavior in metro stations play an important role in supporting suicide prevention efforts, where early identification of high-risk situations can enable timely intervention. This requires assessing suicide risk from a surveillance video by jointly reasoning about the behavior of each passenger, his/her spatial context, and temporal dynamics. However, this assessment using videos captured by surveillance cameras is challenging, as it demands accurate perception of human motion, understanding of platform geometry, and aggregation of heterogeneous behavioral cues over time. In this work, we formalize the task of Suicide Risk Assessment (SRA) in metro stations and introduce the first interpretable framework that addresses this challenge. Unlike approaches that focus on isolated subtasks or attempt to infer intent directly, our formulation assesses suicide risk from accumulated evidence by incorporating person tracking, activity recognition, semantic segmentation of the platform, and trajectory-driven risk heatmap modeling. By formalizing SRA as a distinct task and benchmarking a complete operational pipeline achieving 83.2% ROC-AUC on real surveillance data, this work highlights the complexity of suicide risk assessment and opens new directions for research on interpretable AI systems for social good.

Statistical decision algorithms are increasingly deployed in domains where ground-truth labels are hard to obtain, such as hiring, university admissions, and content moderation. In these settings, models are typically trained on historical human evaluations -- for example, using past hiring decisions as a proxy for true applicant quality. However, if past evaluations unjustly favor certain groups, models trained on these labels may inherit those biases. To address this problem, we propose basing predictions on rubric embeddings, a representation framework that replaces standard black-box embeddings with features derived from expert-defined criteria that align with the underlying construct of interest. By anchoring predictions to semantically meaningful dimensions, this approach guards against biased proxy signals. We provide both theoretical and empirical evidence that rubric embeddings mitigate label bias under plausible conditions. Empirically, we evaluate our method on a novel dataset of applications to a large master's program. We find that models trained on rubric embeddings reduce group disparities while improving measures of cohort quality. Our results suggest that basing predictions on interpretable, domain-grounded representations offers a practical approach to learning in the presence of biased labels.

Interpretable text representations should expose coordinates that are not only predictive, but also meaningful enough for independent auditors to apply. Existing discriminative representations often use anonymous embedding directions, while concept-bottleneck and LLM-assisted methods attach natural-language names to features without ensuring that those definitions are reproducible or distinct from the target label. We propose an operational criterion for interpretable discriminative text representations: each coordinate should satisfy conceptual clarity, measured by chance-adjusted agreement between independent annotators applying the feature definition, and label disentanglement, meaning the feature should not merely paraphrase the prediction target. We instantiate this criterion in LLM-assisted Feature Discovery (LFD), an iterative method that proposes lexical and semantic features from contrastive outcome-opposed text pairs, screens candidates using cross-LLM Cohen's $κ$, and selects features by residual held-out predictive gain. A stylized analysis connects the $κ$ screen to a per-feature annotation-noise bound, formalizing agreement as a reliability check. Across ten text-classification tasks spanning seven corpora, LFD matches the predictive performance of a strong text bottleneck baseline while producing substantially clearer and less label-entangled features. Human audits with 232 raters show that LFD features achieve higher human--human and human--LLM agreement than baseline concepts, and raters consistently judge them as less label-leaking. These results suggest that agreement-tested, label-disentangled coordinates provide a practical auditability standard for interpretable text classification.

Non-destructive testing of aerospace SiC/SiC composites via X-ray computed tomography (XCT) relies on expert visual assessment, with current workflows offering limited traceability for accept/reject decisions. Deep convolutional networks can automate defect detection, yet their black-box nature conflicts with the transparency that industrial inspection practice demands. To close this gap, we introduce p-ResNet-50, a convolutional framework extended with a prototype layer that couples high detection accuracy with case-based explanations. Six learned prototypes are explicitly aligned with expert-defined semantic categories-healthy matrix, matrix--air interfaces, pores, line-like defects, and mixed morphologies-so that every classification is traceable to a physically meaningful reference. Two novel regularisation terms, anchor-based and medoid-based, tether prototypes to expert-selected patches and prevent prototype collapse, addressing a known limitation of prototype networks. Latent-space analysis via UMAP delineates semantically coherent sub-domains and maps zones of uncertainty where misclassifications concentrate, giving inspectors an explicit picture of where the model is-and is not-reliable. The framework is validated on an XCT patch dataset of approximately 12,000 patches extracted from four defect-rich SiC/SiC laboratory specimens. Taking a black-box ResNet-50 as a baseline (ROC-AUC = 0.991), the prototype extension achieves comparable performance (accuracy 0.957 vs. 0.959; ROC-AUC 0.994 vs. 0.993) while trading a slight reduction in sensitivity for higher precision and specificity. Each decision is backed by representative evidence patches, and the model explicitly flags its uncertainty regions. Beyond defect mapping, the framework establishes a reusable methodology for embedding domain-expert knowledge into prototype networks, applicable to other XCT inspection scenarios requiring traceable, auditable decisions.

Accurate disease risk prediction is challenged by heterogeneous features, limited data, and class imbalance. This study presents yvsoucom-iterkit, a deterministic AutoML framework that models pipeline optimization as a configuration-level system with full reproducibility and traceable execution logs, enabling systematic analysis of component attribution, interactions, similarity, and cross-seed robustness. Experiments on the Pima Indians Diabetes and Stroke datasets across more than 18,000 pipeline configurations reveal a structured yet partially redundant search space, where performance is dominated by a small subset of interacting components. Ensemble models achieve stable performance, reaching a Weighted-F1 of 0.89 on Pima and 0.94 on Stroke. Macro-F1 reaches approximately 0.88 on Pima but drops to 0.6560 on Stroke due to severe imbalance. Cross-seed experiments show that ensembles reduce variance compared to single models. Friedman testing ($p < 0.05$) confirms significant ranking differences across configurations. Based on analysis of component attribution, interaction, and similarity, optimal configuration design reveals dataset-dependent behavior. For the Pima dataset, computational efficiency benefits from simplified search spaces where redundant components can be removed, with split ratio playing a key role. In contrast, the Stroke dataset requires enhanced imbalance-aware strategies, where RandomOverSampler improves Macro-F1 from 0.6560 to 0.6766. These findings demonstrate that effective AutoML optimization is achieved through optimal configuration design, where carefully constraining the search space to high-impact components can improve performance, stability, and interpretability while reducing unnecessary search complexity.

Discovering shapelets -- i.e., discriminative temporal patterns within time series -- has been widely studied to address the inherent complexity of time-series classification (TSC) and to make model decision-making processes more transparent. However, existing methods primarily focus on population-level shapelets optimized across the entire dataset, which leads to two fundamental limitations: (i) population-level patterns often misalign with instance-specific features, resulting in suboptimal performance and potentially misleading interpretations, and (ii) most methods treat shapelets as independent entities, overlooking important temporal dependencies and interactions among multiple patterns. To address these limitations, we propose INSHAPE, an interpretable TSC framework that discovers variable-length, discriminative temporal patterns specific to each time series. INSHAPE identifies these patterns as non-overlapping segments and models their temporal dependencies, thereby providing clear instance-level interpretations while achieving strong predictive performance. Furthermore, INSHAPE bridges local and global interpretability through a bottom-up approach, aggregating instance-level shapelets into prototypical (population-level) shapelets. Extensive experiments on 128 UCR and 30 UEA benchmark datasets show that INSHAPE consistently outperforms state-of-the-art shapelet-based methods while providing more intuitive and interpretable insights.

Automated sleep staging is commonly approached as a supervised machine learning problem, with deep learning methods dominating recent research. While machine learning models achieve near-human level agreement with human-scored reference sleep stages, their decisions are typically opaque and not designed to follow clinical scoring rules. We propose a transparent alternative: a deterministic, rule-based sleep staging method that explicitly operationalizes the American Academy of Sleep Medicine's (AASM) scoring logic as executable code, coupled with epoch-level natural-language justifications derived from an explanation trace. We evaluate the approach on 50 polysomnography recordings with a 10-scorer majority-vote consensus as reference. Across all recordings, the method agreed with the majority-vote reference in 60.5% of epochs ($κ=0.42$), with substantially higher agreement on a dataset used during development (77.1%, $κ=0.61$). Agreement with the reference was highest for sleep stage N2 (recall 83.5%) and moderate for sleep stage R (recall 68.7%), while Wake and N1 recall were low. Despite lower agreement with the reference than contemporary deep learning models, the method provides deterministic decisions and natural language explanations aligned with AASM scoring rules, making it a complementary tool for auditing, debugging, and governing deep learning-based sleep staging.

Many clinical risk scores are deployed as additive rules with nonnegative integer points assigned to relevant binary predictive features. These integer weights not only make the score easier to use in practice but also promote sparsity in the resulting prediction model. Such risk scores are often derived by first fitting a regression model and then rounding the estimated coefficients to the nearest integer after appropriate scaling. This approach is computationally fast but does not guarantee optimality of the resulting score. Alternatively, one may search over all possible integer weights to directly optimize a value function by posing the problem as an integer programming task. However, the associated computational burden can be substantial, especially when the value function is nonconcave or even discontinuous. In this paper, we develop new machine learning algorithms that employ a flexible greedy optimization strategy to learn such additive scoring directly under explicit and sensible optimality objectives. We apply the proposed method to a large electronic health record (EHR) cohort in Epic Cosmos to construct an integer-weighted comorbidity score for measuring the risk of post-discharge mortality. We also conduct a simulation study to examine the finite-sample operating characteristics.

Virtually all aspects of many-body atomic physics are challenging: experiments are technically demanding, datasets have become enormous, and the memory and CPU requirements for classical simulation of generic quantum systems often scale exponentially with system size. Machine learning (ML) methods are already assisting in each of these areas and are poised to become transformative. Here, we focus on two specific applications of ML to cold-atom-based quantum simulators. These devices generally generate data in the form of images; we first showcase denoising of raw images and then identify solitonic waves in Bose-Einstein condensates. In both of these examples, we comment on the interplay between performance, model complexity, and interpretability.

Deep reinforcement learning (DRL) has recently emerged as a promising approach to solve combinatorial optimization problems such as job shop scheduling. However, the policies learned by DRL are typically represented by deep neural networks (DNNs), whose opaque neural architectures and non-interpretable policy decisions can lead to critical trust and usability concerns for human decision makers. In addition, the computational requirements of DNNs can further hinder practical deployment in resource constrained environments. In this work, we propose ProRL, a novel interpretable programmatic reinforcement learning framework that achieves high-performance scheduling with human-readable and editable programmatic policies (i.e., programs). We first introduce a domain-specific language for scheduling (DSL-S) to represent scheduling strategies as structured programs. ProRL then explores the program space defined by DSL-S using local search to identify incomplete programs, which are subsequently completed by learning their parameters via Bayesian optimization. ProRL learns which scheduling heuristic rules to select, and hence, it naturally incorporates existing heuristics already used in industrial scenarios. Experiments on widely used benchmark instances demonstrate the strong performance of ProRL against existing heuristics and DRL baselines. Furthermore, ProRL performs well under strongly constrained computational resources, such as training with only 100 episodes. Our code is available at https://github.com/HcPlu/ProRL.

The functional ANOVA, or Hoeffding decomposition, provides a principled framework for interpretability by decomposing a model prediction into main effects and higher-order interactions. For independent inputs, this classical decomposition is explicit. It is closely connected to SHAP values, generalized additive models, and orthogonal polynomial expansions, and therefore constitutes a fundamental tool for additive explainability. In the more general and realistic dependent setting, however, obtaining a tractable representation and estimating the decomposition from data remain challenging. In this work, we address this problem for continuous inputs. By combining Hilbert space methods with the generalized functional ANOVA, we build an explicit decomposition Riesz Basis allowing to easily compute the decomposition. Our formulation recovers the classical independent case and its associated orthogonal decomposition. Building on this representation, we propose a simple but mighty algorithm to estimate the decomposition from a data sample in a model-agnostic setting and we compare it empirically with several state-of-the-art explanation methods, demonstrating the power of the approach.

Deep learning-based methods have become the de facto standard for industrial defect detection. However, their data-hungry nature and inherent "black-box" characteristics often lead to performance bottlenecks and limited trustworthiness in real-world applications. To address these challenges, this paper proposes a novel knowledge-guided loss function that seamlessly integrates model interpretability into the training process without incurring any additional inference cost. Our method operates in two phases: first, a primary classification network is trained, and its explanations, in the form of saliency maps, are generated as prior knowledge. Second, a multi-task learning framework is established, where the main task performs classification, and an auxiliary task imposes consistency between the saliency maps of the final model and the primary model. This consistency is enforced by a dedicated knowledge-guided loss term, effectively acting as a powerful regularizer to steer the model towards robust feature representations. Extensive experiments on multiple public defect datasets demonstrate that our approach consistently enhances the performance of baseline models in terms of accuracy and AP. Moreover, visual analysis reveals that the proposed method yields more concentrated and human-intelligible saliency maps. This work presents a simple yet effective paradigm for bridging the gap between model performance and interpretability, paving the way for more reliable and high-performing vision systems in industrial quality inspection.

This paper presents an interpretable closed-loop Intelligent Tutoring System (ITS) that supports feedback-guided practice for developing on-camera oral presentation skills at scale. The system operationalizes a seven-dimensional Behaviorally Anchored Rating Scale (BARS) and implements a three-layer interpretable feedback architecture that connects rubric-aligned multimodal scoring, audience-perceived expressive diagnostics, and retrieval-augmented conversational coaching to support deliberate practice. Built on an XGBoost backbone, the ITS maps multimodal inputs (facial, vocal, textual, and oculomotor features) into evidence-based feedback that can be traced back to observable performance cues. Trained on 10,360 Massive Open Online Course (MOOC) video segments, the system achieved rubric-aligned scoring with performance levels comparable to expert ratings (R2 = 0.48-0.61, Spearman's rho = 0.69-0.78, MAE = 0.43-0.57). In a pre-post validation study with 204 adult learners over a 30-day practice window, participants demonstrated significant improvements across all seven BARS dimensions (Cohen's d = 0.39-0.90), with practice frequency showing a strong positive association with posttest performance after controlling for baseline scores and demographics. The results demonstrate how multimodal analytic outputs can be systematically transformed into observable behavioral change through an integrated feedback architecture, advancing explainable and pedagogically grounded ITS design for performance-based competencies.

The rapid evolution of digital health technologies is redefining healthcare services worldwide. The integration of wireless communication and Internet-enabled medical devices within Internet of Medical Things (IoMT) networks enables continuous, real-time patient monitoring. However, this increased connectivity raises cybersecurity and patient safety risks due to increasingly sophisticated cyberattacks. This paper proposes a novel on-device, interpretable Tsetlin Machine (TM)-based Intrusion Detection System (IDS) to identify various phases of cyberattacks in IoMT environments. The TM is a rule-driven and transparent machine learning (ML) approach that represents attack patterns using propositional logic. Extensive evaluations on the MedSec-25 dataset, encompassing various phases of realistic cyberattacks, show that the proposed model outperforms ML models, attaining an F1-score (macro) of 97.83%. Moreover, the proposed model offers explicit explanations of its decisions to enhance transparency using feature-level contributions, class-wise vote scores, and clause activation heatmaps. Edge deployment (Raspberry Pi) further supports real-time on-device inference and intrusion detection. The combination of interpretability and high performance makes the proposed model well-suited for IoMT healthcare, where trust, reliability, safety, and timely decision-making are critical.

Every day, users generate digital traces (e.g., social media posts, chats, and online interactions) that are inherently timestamped and may reflect aspects of their mental state. These traces can be organized into temporal trajectories that capture how a user's mental health signals evolve, including phases of improvement, deterioration, or stability. In this work, we propose an explainable framework for detecting and analyzing depression-related status shifts in user digital traces. The approach combines multiple BERT-based models to extract complementary signals across different dimensions (e.g., sentiment, emotion, and depression severity). Such signals are then aggregated over time to construct user-level trajectories that are analyzed to identify meaningful change points. To enhance interpretability, the framework integrates a large language model to generate concise and human-readable reports that describe the evolution of mental-health signals and highlight key transitions. We evaluate the framework on two social media datasets. Results show that the approach produces more coherent and informative summaries than direct LLM-based reporting, achieving higher coverage of user history, stronger temporal coherence, and improved sensitivity to change points. An ablation study confirms the contribution of each component, particularly temporal modeling and segmentation. Overall, the method provides an interpretable view of mental health signals over time, supporting research and decision making without aiming at clinical diagnosis.

Graph Neural Networks (GNNs) have advanced significantly in handling graph-structured data, but a comprehensive framework for evaluating explainability remains lacking. Existing evaluation frameworks primarily involve post-hoc explanations, and operate in the setting where multiple methods generate a suite of explanations for a single model. This makes comparison of explanations across models difficult. Evaluation of inherently interpretable models often targets a specific aspect of interpretability relevant to the model, but remains underdeveloped in terms of generating insight across a suite of measures. We introduce AIM, a comprehensive framework that addresses these limitations by measuring Accuracy, Instance-level explanations, and Model-level explanations. AIM is formulated with minimal constraints to enhance flexibility and facilitate broad applicability. Here, we use AIM in a pipeline, extracting explanations from inherently interpretable GNNs such as graph kernel networks (GKNs) and prototype networks (PNs), evaluating these explanations with AIM, identifying their limitations and obtaining insights to their characteristics. Taking GKNs as a case study, we show how the insights obtained from AIM can be used to develop an updated model, xGKN, that maintains high accuracy while demonstrating improved explainability. Our approach aims to advance the field of Explainable AI (XAI) for GNNs, providing more robust and practical solutions for understanding and improving complex models.

Pattern discovery in data plays a crucial role across diverse domains, including healthcare, risk assessment, and machinery maintenance. In contrast to black-box deep learning models, symbolic rule discovery emerges as a key data mining task, generating human-interpretable rules that offer both transparency and intuitive explainability. This paper introduces the Optimal Pattern Detection Tree (OPDT), a rule-based machine learning model based on novel mixed-integer programming to discover a single optimal pattern in data through binary classification. To incorporate prior knowledge and compliance requirements, we further introduce the Branching Structure Constraints (BSC) framework, which enables decision makers to encode domain knowledge and constraints directly into the model. This optimization-based approach discovers a hidden underlying pattern in datasets, when it exists, by identifying an optimal rule that maximizes coverage while minimizing the false positive rate due to misclassification. Our computational experiments show that OPDT discovers a pattern with optimality guarantees on moderately sized datasets within reasonable runtime.

Predictive maintenance in complex systems is often complicated by the heterogeneity and redundancy of monitored variables,which can obscure fault-relevant information and reduce model interpretability. This work proposes a semantic feature segmentation framework that decomposes the monitored feature space into a canonical component,expected to retain the dominant predictive information, and a residual component containing structurally peripheral signals. The segmentation is defined through domain informed criteria and sets up monitoring variables into functional groups reflecting operational mechanisms such as throughput,latency,pressure,network activity,and structural state. To evaluate the effectiveness of this decomposition, we adopt a predictive perspective in which expected predictive risk is used as an operational proxy for task-relevant information. Experimental results obtained through time-aware cross-validation show that the canonical space consistently achieves lower predictive risk than the residual space across multiple temporal configurations, indicating that the semantic segmentation concentrates the most relevant information for fault anticipation. In addition, the canonical segments exhibit significantly stronger intra-segment coherence than inter-segment dependence, and this structural organization remains stable after redundancy reduction. When compared with the full feature space and with a Principal Component Analysis (PCA) representation, the canonical space carries out comparable predictive performance and furthermore preserves the semantic meaning of the original variables. These findings suggest that semantic feature segmentation provides an interpretable and information-preserving decomposition of monitoring signals, enabling competitive predictive performance without sacrificing the operational interpretability required in predictive maintenance applications.

While interpretable prototype networks offer compelling case-based reasoning for clinical diagnostics, their raw continuous outputs lack the semantic structure required for medical documentation. Bridging this gap via standard Retrieval-Augmented Generation (RAG) routinely triggers ``retrieval sycophancy,'' where Large Language Models (LLMs) hallucinate post-hoc rationalizations to align with visual predictions. We introduce ProtoMedAgent, a framework that formalizes multimodal clinical reporting as an iterative, zero-gradient test-time optimization problem over a strict neuro-symbolic bottleneck. Operating on a frozen prototype backbone, we distill latent visual and tabular features into a discrete semantic memory. Online generation is strictly constrained by exact set-theoretic differentials and a reflective Scribe-Critic loop, mathematically precluding unsupported narrative claims. To safely bound data disclosure, we introduce a semantic privacy gate governed by $k$-anonymity and $\ell$-diversity. Evaluated on a 4,160-patient clinical cohort, ProtoMedAgent achieves 91.2% Comparison Set Faithfulness where it fundamentally outperforms standard RAG (46.2%). ProtoMedAgent additionally leverages a binding $\ell$-diversity phase transition to systematically reduce artifact-level membership inference risks by an absolute 9.8%.

Explainability methods have progressed rapidly, but global explanations for time-series models remain underdeveloped, with most approaches focusing on local, instance-level attributions. We introduce INSIGHTS, a model-agnostic, user-centric approach for providing global explanations of time series models. Our approach prioritizes simplicity, efficiency, and transparency in its design, ensuring that stakeholders can readily adopt its outputs. While current methods focus on local explanations, INSIGHTS generates sample summaries that offer a comprehensive overview of model behavior. It balances the importance and diversity of time series samples to create informative subsets using utility functions that capture domain-specific aspects of time series behavior, such as exceeding domain norms. We evaluate INSIGHTS through experiments, interviews, and a user study. Our results indicate INSIGHTS effectively constructs comprehensive, diverse time series subsets, producing summaries manageable for individual evaluation. It is preferred by domain experts for its ability to provide a stable understanding of model behavior and the quality of the samples identified. Moreover, user study participants presented with INSIGHTS-based summaries exhibit an enhanced understanding of the model's overall behavior.

Interpretable machine learning aims to provide transparent models whose decision-making processes can be readily understood by humans. Recent advances in rule-based approaches, such as expressive Boolean formulas (BoolXAI), offer faithful and compact representations of model behavior. However, for non-technical stakeholders, main challenges remain in practice: (i) selecting semantically meaningful features and (ii) translating formal logical rules into accessible explanations. In this work, we propose BoolXLLM , as a hybrid framework that integrates Large Language Models (LLMs) into the end-to-end pipeline of Boolean rule learning. We augment BoolXAI , an expressive Boolean rule-based classifier, with LLMs at three critical stages: (1) feature selection, where LLMs guide the identification of domain-relevant variables; (2) threshold recommendation, where LLMs propose semantically meaningful discretization strategies for numerical features; and (3) rule compression and interpretation, where Boolean rules are translated into natural language explanations at both global and local levels. This integration bridges formal, faithful explanations with human-understandable narratives. This allows build an explainable AI system that is both theoretically grounded and accessible to non-experts. Early empirical results demonstrate that LLM-assisted pipelines improve interpretability while maintaining competitive predictive performance. Our work highlights the promise of combining symbolic reasoning with language-based models for human-centered explainability.

The EU Artificial Intelligence Act (Regulation 2024/1689), fully applicable to high-risk systems from August 2026, creates urgent demand for AI architectures that are simultaneously trustworthy, transparent, and feasible to deploy on resource-constrained edge devices. Brain-like neural networks built on the Bayesian Confidence Propagation Neural Network (BCPNN) formalism have re-emerged as a credible alternative to backpropagation-driven deep learning. They deliver state-of-the-art unsupervised representation learning, neuromorphic-friendly sparsity, and existing FPGA implementations that target edge deployment. Despite this momentum, no systematic framework exists for explaining BCPNN decisions -- a gap the present paper fills. We argue that BCPNN is, in the sense of Rudin's interpretable-by-design agenda, an inherently transparent model whose architectural primitives map directly onto established explainable-AI (XAI) families. We make four contributions. First, we propose the first XAI taxonomy for BCPNN. It maps weights, biases, hypercolumn posteriors, structural-plasticity usage scores, attractor dynamics, and input-reconstruction populations onto attribution, prototype, concept, counterfactual, and mechanistic explanation modalities. Second, we introduce sixteen architecture-level explanation primitives (P1--P16), several without analogue in standard ANNs. We provide closed-form algorithms for computing each from quantities the model already maintains. Third, we introduce five design-time Configuration-as-Explanation primitives (Config-P1 to Config-P5) that treat BCPNN hyperparameter choices as an auditable pre-deployment explanation artifact. Fourth, we sketch a roadmap for integration into industrial IoT deployments and discuss EU AI Act alignment, edge feasibility, and Industry 5.0 implications.

Existing granular-ball classification methods are often driven by handcrafted quality measures, neighborhood rules, or heuristic splitting and stopping criteria, which may reduce the transparency of local construction decisions and hinder explicit modeling of boundary-sensitive regions. To address this issue, this paper proposes a Minimum Description Length based Granular-Ball Classifier (MDL-GBC), a boundary-aware non-parametric and interpretable granular-ball classifier. MDL-GBC formulates class-conditional granular-ball construction as a local model selection problem under the Minimum Description Length principle. For each class, samples from the target class provide positive class evidence, while samples from the remaining classes provide negative boundary evidence. For each current granular ball, three candidate explanations are compared under a unified description-length criterion: a single-ball model, a two-ball model, and a core-boundary model. The selected model determines whether the ball is retained, geometrically split, or refined into core and boundary-sensitive child balls, thereby making local construction decisions consistent with the MDL-based classification mechanism. During prediction, a class-level mixture coding rule aggregates stable granular balls of the same class and assigns the test sample by comparing class-wise coding costs. Experiments on 18 benchmark datasets show that MDL-GBC achieves competitive classification performance against classical classifiers and representative granular-ball-based methods, obtaining the best average Accuracy, Macro-F1, and average rank. These results indicate that MDL-GBC provides an effective and interpretable alternative to conventional heuristic granular-ball classification strategies.

Automated ASD screening tools remain limited by single-architecture evaluations, axis-restricted assessment, and near-exclusive focus on adult cohorts, obscuring age-specific diagnostic patterns critical for early intervention. We introduce ASD-Bench, a systematic tabular benchmark evaluating ML, deep learning, and foundation model configurations across three age cohorts (children 1-11 yr, adolescents 12-16 yr, adults 17-64 yr) on four axes: predictive performance, calibration, interpretability, and adversarial robustness. Applied to a curated v3 dataset of 4,068 AQ-10 records, our benchmark spans classical models (XGBoost, AdaBoost, Random Forest, Logistic Regression), neural networks (MLP), deep tabular transformers (TabNet, TabTransformer, FT-Transformer), and TabPFN v2. We introduce the Heuristic Aggregate Penalty (HAP): a cost-sensitive metric penalising false negatives more heavily and incorporating cross-validation variance for deployment stability. Adult classification yields high performance (10/17 models achieve perfect F1 and AUC), while adolescents present a harder task (F1 ceiling 0.837 vs. 0.915 for children). Feature hierarchies shift across cohorts: A9 (social motivation) dominates for children, A5 (pattern recognition) leads for adolescents, and adults exhibit a flatter importance profile consistent with developmental social masking. Accuracy and calibration are dissociated: AdaBoost achieves F1=1.000 on adults with ECE=0.302, confirming single-metric evaluation is insufficient for clinical AI. Cohort-specific deployment recommendations are provided. All findings should be interpreted as proof-of-concept evidence on questionnaire-derived labels rather than clinically validated diagnostic performance.

Knowledge Tracing (KT) models students' knowledge states based on learning interactions to predict performance. While deep learning-based KT models have boosted predictive accuracy, most models rely on deterministic vector embeddings and opaque latent state transitions, limiting interpretability regarding how specific past behaviors influence predictions. To address this limitation, we propose Probabilistic Logical Knowledge Tracing (PLKT), an interpretable KT framework that formulates prediction as a goal-conditioned evidence reasoning process over historical learning behaviors. Instead of representing knowledge states as deterministic vector embeddings, PLKT employs robust Beta-distributed probabilistic embeddings to represent student knowledge states. This probabilistic foundation allows us to model the uncertainty of historical behaviors and perform explicit logical operations (e.g., conjunction), constructing transparent reasoning paths that reveal how specific past interactions contribute to the prediction. Extensive experiments show that PLKT outperforms state-of-the-art KT methods while achieving superior interpretability. Our code is available at https://anonymous.4open.science/r/PLKT-D3CE/.

Multiphoton photoreduction enables high-fidelity fabrication of complex 3D microstructures, yet reliable process-structure-property (PSP) prediction remains difficult because the available data are sparse, heterogeneous, and interaction-dominated. In this regime, conventional feature-vector models are statistically underdetermined, making them prone to spurious correlations, poor regime transfer, and unstable post hoc explanations, whereas mechanistic pipelines depend on calibrated submodels that are rarely available during early process development. We present PSP-HDC, a graph-structured hyperdimensional computing framework that encodes a directed PSP graph as an internal prior for representation, inference, and explanation. A trainable scalar-to-hypervector encoder learns parameter-specific embeddings on a fixed hyperdimensional basis to accommodate heterogeneous scales and noise. Sample representations are then composed through graph-aligned binding and bundling along directed PSP dependencies, and prediction is performed by associative-memory retrieval against class prototypes. Because the same prototype memories support both decision making and attribution, PSP-HDC provides intrinsic explanations at the parameter, group, and within-group levels, while memory alignment and separation quantify prototype formation during training. On sheet-resistance regime prediction for the 3D platform, PSP-HDC achieves an accuracy of 0.910 +/- 0.077 over 1000 random splits and 0.896 under process-fold generalization, outperforming strong baselines.

Relational learning is a challenging problem that has motivated a wide range of approaches, including graph-based models (e.g., graph neural networks, graph transformers), tabular methods (e.g., tabular foundation models), and sequence-based approaches (e.g., large language models), each with its own advantages and limitations. We propose RelAgent, an LLM-based autonomous data scientist for relational learning, which operates in two phases. In the search phase, an LLM agent uses database, validation, and evaluation workspace tools to construct SQL feature programs and select a predictive model. In the inference phase, the resulting program is executed without further LLM calls. The final predictor consists of SQL queries and a classical model, enabling fast, deterministic, and intrinsically interpretable predictions: features are human-readable queries, and predictions depend only on the resulting query-defined feature map, enabling scalable deployment using standard database systems.

Decision Trees (DTs) are widely used in safety-critical domains such as medical diagnosis, valued for their interpretability and effectiveness on tabular data. However, training accurate oblique DTs is challenging due to complex optimization landscapes and overfitting risks, particularly in regression. Recent advances have introduced differentiable formulations that enable gradient-based training and joint optimization of decision boundaries and leaf regressors. Yet, existing approaches typically rely on approximations, either through probabilistic softening of boundaries (soft DTs) or quantized gradients such as the Straight-Through Estimator (STE). To overcome these limitations, we propose DTSemNet, a novel, semantically equivalent, and invertible representation of hard oblique DTs as neural networks. DTSemNet enables end-to-end training with standard gradient descent, eliminating the need for approximations in both classification and regression. While classification aligns naturally with this formulation, regression remains challenging due to the joint optimization of internal nodes and leaf regressors. To address this, we analyze the limitations of STE and introduce an annealed Top-k method that provides accurate gradient signals without approximation. Extensive experiments on classification and regression benchmarks show that DTSemNet-trained oblique DTs outperform state-of-the-art differentiable DTs. Furthermore, we demonstrate that DTSemNet can serve as programmatic DT policies in reinforcement learning environments, thereby broadening their applicability.

Skeleton-based human activity recognition has achieved strong empirical performance, yet most existing models remain black boxes and difficult to interpret. In this work, we introduce a neurosymbolic formulation of skeleton-based HAR that reframes action recognition as concept-driven first-order logical reasoning over motion primitives. Our framework bridges representation learning and symbolic inference by grounding first-order logic predicates in learnable spatial and temporal motion concepts. Specifically, we employ a standard spatio-temporal skeleton encoder to extract latent motion representations, which are then mapped to interpretable concept predicates via a spatio-temporal concept decoder that explicitly separates pose-centric and dynamics-centric abstractions. These concept predicates are composed through differentiable first-order logic layers, enabling the model to learn human-readable logical rules that govern action semantics. To impose semantic structure on the learned concepts, we align skeleton representations with LLM-derived descriptions of atomic motion primitives, establishing a shared conceptual space for perception and reasoning. Extensive experiments on NTU RGB+D 60/120 and NW-UCLA demonstrate that our approach achieves competitive recognition performance while providing explicit, interpretable explanations grounded in logical structure. Our results highlight neurosymbolic reasoning as an effective paradigm for interpretable spatio-temporal action understanding. Code: https://github.com/Mr-TalhaIlyas/REASON

In domains where both predictive performance and interpretability are essential, deep neural networks achieve strong results but provide limited insight into how their predictions are made. Projection-based prototype networks address this limitation by grounding predictions in similarity to representative training examples, enabling case-based explanations and global prototype inspection. However, existing approaches rely on label supervision, tying prototypes to a specific task and requiring large labeled datasets. We introduce ProtoSSL, a framework for pretraining a foundational latent prototype bank on unlabeled data and transferring it to downstream tasks to create interpretable, projection-based prototype models. Our key idea is to separate motif discovery from label alignment. ProtoSSL first learns a transferrable prototype bank using a self-supervised objective applied directly to prototype activations, and then aligns these prototypes to downstream tasks through a novel efficient assignment procedure. Across six electrocardiography (ECG) datasets, ProtoSSL improves label efficiency, outperforming supervised prototype baselines in low-data regimes with as few as 256 labeled examples; with fine-tuning, ProtoSSL outperforms supervised prototype baselines at full dataset scale. In a human evaluation study, ProtoSSL produces prototypes and prototype-based explanations that are judged more favorably than those learned with direct label supervision. We further show that the framework extends to audio classification. Thus, ProtoSSL enables both learning foundational prototypes from unlabeled data before the downstream label space is known, and subsequent assignment to new tasks to create interpretable, projection-grounded prototypes.