Cross-Modal Alignment

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Overview

Cross-modal alignment studies how to connect information from different data types, such as images and text, audio and video, or brain signals and visual features, so models can retrieve, interpret, or generate across them. Common approaches use contrastive learning and shared embedding spaces, alongside optimal transport, prototypes, geometric mappings, and local or temporal correspondence; some methods rely on weakly paired or unpaired data. Work is evaluated on tasks such as image-text retrieval, grounding, zero-shot transfer, and multimodal generation, including in medical and scientific settings. A central tension is how to align shared meaning without erasing useful modality-specific information, since stronger alignment scores do not always translate into better downstream performance or consistent behavior across tasks.

Latest papers

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446 papers47 papers in the last four weeks, up 4% on the four weeks before. 0.3% of all new papers.

May 19, 2026

Precise and Simple Audio-to-Score Alignment

Audio-to-score alignment is a long-standing challenge in music information retrieval and arguably the most widely applicable alignment task for music research. Alignment algorithms match two versions of a piece of music, and for this to work these versions need to be in comparable formats. Audio-to-audio alignment matches audio features; when matching audio files to scores, they must either synthesize the score or derive audio-like features by means of piano rolls or similar feature sequences. Symbolic alignment, by contrast, matches symbolically encoded notes; in an audio-to-score scenario these would be obtained by a transcription of the audio file. In this article, we present an algorithm that bridges audio-like and symbol-level features directly. Sequential audio features encoding onset and spectral activation are matched to score positions by a bespoke dynamic programming-based matching algorithm derived from symbolic alignment methods. The resulting method is both precise - surpassing widely used audio-to-audio approaches based on synthesized scores -, and remains flexible in its digital signal processing components, i.e., the method is adaptable to diverse timbral characteristics without requiring a separate transcription model. Furthermore it inherits some of the symbolic alignment runtime advantages with an algorithmic complexity that is at worst linear in the length of the (typically short) symbolic score and (typically long) audio feature sequence. In the following sections, we provide a detailed algorithm description and evaluate its alignment quality on a large-scale dataset of solo piano recordings.

Silvan Peter, Patricia Hu, Gerhard Widmer

Institute of Computational Perception, Johannes Kepler University, Linz, Austria · LIT AI Lab, Linz Institute of Technology, Linz, Austria

Cross-Modal AlignmentMusic Information RetrievalSequence Alignment
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May 19, 2026

MSAlign: Aligning Molecule and Mass Spectra Foundation Models for Metabolite Identification

Accurately identifying metabolites i.e. small molecules from mass spectrometry data remains a core challenge in metabolomics, with broad applications in drug discovery, environmental analysis, and clinical research. We address the Molecule Retrieval task, which consists in recovering the chemical structure of a metabolite from its MS/MS spectrum given a set of candidate molecules. While the recent release of benchmark datasets such as MassSpecGym and Spectraverse has considerably accelerated the development of novel machine learning approaches, the complexity of data preprocessing pipelines and the lack of unified implementations make methods and results difficult to reproduce and compare. We make three contributions. First, we propose a unified framework encompassing recent approaches based on representation alignment and contrastive learning. Second, we introduce MSAlign, inspired by multimodal alignment in vision-language models, which learns a shared representation space by aligning two frozen foundation models (DreaMS for mass spectra and ChemBERTa for molecules) through lightweight MLP projections trained with a candidate-based contrastive objective. MSAlign is simple to implement, fast to train and consistently outperforms existing approaches across all benchmarks. Third, we investigate a long-standing evaluation problem: data splitting strategies in molecule retrieval implicitly trade off data leakage against domain shift. We formalize this tension by introducing a quantitative measure of distribution shift, and use it to evaluate splitting strategies in existing benchmarks. All datasets, splits, candidate sets, and a unified implementation of MSAlign and baselines are publicly released to support reproducible research.

Paul Krzakala, Gabriel Melo, Camille Lançon +4

LTCI, Télécom Paris & CMAP, Ecole Polytechnique, Institut Polytechnique de Paris · LTCI, Télécom Paris, Institut Polytechnique de Paris · CEA, INRAE, MetaboHUB, Université Paris-Saclay +1

Distribution ShiftCross-Modal AlignmentCross-Modal RetrievalMass Spectrometry
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May 19, 2026

Tango3D: Towards Alignment for Global and Local 2D-3D Correspondence

Existing 3D foundation models typically align point clouds to frozen vision-language spaces like CLIP, which achieve strong cross-modal retrieval by compressing 3D shape into a global vector. However, this global-only alignment cannot establish fine-grained pixel-to-point correspondence. To solve this, we present Tango3D, a foundation model that unifies dense correspondence and global retrieval. We use a geometry-aware 2D visual backbone and a pretrained 3D VAE to encode images into 2D patches and point clouds into 3D tokens. These are mapped into a single shared space to achieve both local pixel-to-point alignment and global semantic alignment. To stabilize the joint learning of dense and global objectives, we introduce a three-stage progressive training strategy. Experiments show our model successfully achieves object-level pixel-to-point alignment while maintaining competitive global retrieval, a joint capability not offered by existing 3D foundation models. By establishing a fine-grained alignment feature space, Tango3D injects rich semantics into purely geometric 3D tokens, paving the way for a wide range of dense 3D downstream tasks.

Zebin He, Mingxin Yang, Shuhui Yang +4

1HKUST · 2Tencent Hunyuan

3D Foundation ModelsCross-Modal Alignment3D Representation Learning3D VLMs
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May 18, 2026

Semantic Generative Tuning for Unified Multimodal Models

Unified multimodal models (UMMs) strive to consolidate visual understanding and visual generation within a single architecture. However, prevailing training paradigms independently optimize understanding via sparse text signals and generation through dense pixel objectives. Such a decoupled strategy yields misaligned representation spaces, isolating visual understanding from generation and hindering their mutual reinforcement. This work presents the first systematic investigation into generative post-training, where we formulate hierarchical visual tasks as generative proxies to bridge the isolation in UMMs. Our empirical investigation reveals that high-level semantic tasks, particularly image segmentation, serve as optimal proxies. Unlike low-level tasks that distract models with texture details, segmentation provides structural semantics that significantly enhance both vision-centric perception and generative layout fidelity. Building upon these insights, we introduce Semantic Generative Tuning (SGT), a novel paradigm that leverages segmentation as a generative proxy to align and synergize multimodal capabilities. Mechanistic analyses further demonstrate that SGT fundamentally improves feature linear separability and optimizes visual-textual attention allocation pattern. Extensive evaluations show that SGT consistently improves both multimodal comprehension and generative fidelity across mainstream benchmarks. Our code is available on the https://song2yu.github.io/SGT/.

Songsong Yu, Yuxin Chen, Ying Shan +1

Shanghai Jiao Tong University · Tencent ARCLab

Image SegmentationUnified Multimodal ModelsCross-Modal AlignmentMultimodal GenerationMultimodal Understanding
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May 18, 2026

S2Aligner: Pair-Efficient and Transferable Pre-Training for Sparse Text-Attributed Graphs

Pre-training on text-attributed graphs (TAGs) is central to building transferable graph foundation models, where LLM-as-Aligner methods align graph and text representations through the semantic knowledge of large language models. However, these methods usually assume that node texts provide sufficient and reliable supervision, an assumption often violated in real-world sparse TAGs. When textual anchors are missing, noisy, or uneven across domains, graph structures must be aligned with weak semantic evidence, leading to unreliable structure-semantics correspondence and sparsity-induced transfer bias. This paper presents S2Aligner, a sparsity-aware and structure-enhanced LLM-as-Aligner framework for graph-text pre-training on sparse TAGs. The key idea is to decouple semantic alignment from structural modeling, allowing topology-aware signals to enhance alignment without contaminating the shared semantic space. Specifically, S2Aligner decomposes graph-text representations into semantic and structural components, uses structure-oriented reconstruction with consistency control to inject reliable topology cues into text representations, and suppresses inconsistent structural signals under textual sparsity. Moreover, S2Aligner introduces sparsity-aware cross-domain risk balancing, which calibrates domain risks through a global-domain density ratio and downweights unreliable sparse samples via graph reliability estimation. Theoretical analysis shows that this objective reduces cross-domain generalization gaps by controlling domain risk discrepancy. Extensive experiments across diverse graph domains, sparsity levels, and downstream tasks demonstrate that S2Aligner consistently outperforms existing baselines.

Yuhan Wang, Haopeng Zhang, Yibo Ding +6

Beihang University, Beijing, China · Tianjin University, Tianjin, China

Cross-Modal AlignmentText-Attributed Graph LearningCross-Domain Transfer LearningGraph Foundation Models
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May 18, 2026

CodeBind: Decoupled Representation Learning for Multimodal Alignment with Unified Compositional Codebook

Multimodal representation alignment is pivotal for large language models and robotics. Traditional methods are often hindered by cross-modal information discrepancies and data scarcity, leading to suboptimal alignment spaces that overlook modality-unique features. We propose CodeBind, a framework that optimizes multimodal representation spaces through a modality-shared-specific codebook design. By incrementally aligning target and bridging modalities, CodeBind bypasses the need for fully paired data. Unlike traditional hard alignment, CodeBind decomposes features into shared components for semantic consistency and specific components for modality-unique details. This design utilizes a compositional vector quantization scheme, where a shared codebook bridges modality gaps and modality-specific codebooks mitigate representation bias by preventing dominant modalities from overshadowing others. Validated across nine modalities (text, image, video, audio, depth, thermal, tactile, 3D point cloud, EEG), CodeBind achieves state-of-the-art performance in multimodal classification and retrieval tasks.

Zeyu Chen, Jie Li, Kai Han

Visual AI Lab, The University of Hong Kong

Cross-Modal LearningMultimodal Disentangled Representation LearningCross-Modal AlignmentCross-Modal RetrievalMultimodal ClassificationMultimodal Learning
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May 18, 2026

Brain-to-Image Retrieval and Reconstruction via Multimodal EEG Alignment

We present a brain-to-image system that decodes visual stimuli from EEG signals recorded during natural image viewing. Our system addresses two tasks: (1) EEG-to-image retrieval, which ranks the correct stimulus image among 200 candidates given an EEG segment, and (2) EEG-to-image reconstruction, which generates an image consistent with the perceived stimulus. For retrieval, we implement a multi-level blurring approach improved with biologically inspired EVNet features and trained with the InfoNCE loss. Evaluated over 10 random seeds for a single subject, the retrieval model achieves a mean final-epoch Top-1 accuracy of 86.30% and Top-5 accuracy of 98.55%. For reconstruction, we implement CognitionCapturerPro, which aligns EEG representations to multi-modal CLIP embeddings, including image, text, depth, and edge embeddings, and synthesizes images with SDXL-Turbo conditioned via IP-Adapter. Averaged over 10 seeds, the reconstruction model achieves a CLIP score of 0.903 using ViT-H-14, a CLIP score of 0.870 using ViT-L/14, and an SSIM of 0.409. These results demonstrate the feasibility of decoding rich visual representations from EEG signals using modern multi-modal alignment and generative modeling techniques.

Chi Kit Wong, Yan Liu, Haowen Yan

EEG-Based Visual DecodingCross-Modal AlignmentImage ReconstructionCross-Modal Retrieval
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May 18, 2026

LatentUMM: Dual Latent Alignment for Unified Multimodal Models

Unified multimodal models (UMMs) achieve strong performance in both understanding and generation by learning a shared latent space, yet they often exhibit functional inconsistency between these two capabilities. We observe that this issue does not stem from a lack of shared representations, but from the absence of explicit alignment between the transformations that map into and out of the latent space. As a result, generation and re-encoding can follow inconsistent trajectories, leading to semantic drift under modality transitions. In this work, we propose LatentUMM, a framework that constructs an enhanced shared latent space to explicitly align these transformations and improve cross-modal consistency. LatentUMM consists of two stages. First, dual latent alignment enforces consistency at both the modality and capacity levels: cross-modal alignment uses a stronger embedding model to impose structured cross-modal semantics, while dual capacity alignment enforces bidirectional consistency under generation and re-encoding. Second, latent dynamics stabilization improves robustness via stochastic latent rollouts and preference optimization, favoring trajectories that better preserve semantic consistency. Experiments show that LatentUMM consistently improves multimodal consistency across diverse architectures. Code is available at: https://github.com/AIFrontierLab/TorchUMM/tree/main/src/umm/post_training/LatentUMM.

Yinyi Luo, Wenwen Wang, Hayes Bai +2

Carnegie Mellon University · William & Mary

Cross-Modal LearningUnified Multimodal ModelsCross-Modal AlignmentMultimodal Foundation ModelsLatent Space AlignmentMultimodal Understanding
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May 16, 2026

Multilingual and Multimodal LLMs in the Wild: Building for Low-Resource Languages

Multimodal LLMs are evolving from vision-language to tri-modality that see, hear, and read, yet pipelines and benchmarks remain English-centric and compute-heavy. The tutorial offers an overview of this emerging research area for multilingual multimodality across text, speech, and vision under limited data/compute budgets, synthesizing foundations, recent multilingual models (PALO, Maya), speech-text LLMs. We cover low-cost data creation/curation; adapter stacks for tri-modal alignment; culture-aware evaluation beyond English and hands on resources for fine-tuning a compact multilingual VLM and wiring a speech->text->LLM pipeline. The content will be delivered as an interactive half-day tutorial, designed for researchers and practitioners working on multilingual, multimodal AI in low-resource language settings.

Firoj Alam, Shammur Absar Chowdhury, Enamul Hoque Prince

Qatar Computing Research Institute, HBKU, Qatar · York University, Canada

Cross-Modal AlignmentMultimodal Large Language ModelsMultimodal Foundation ModelsLow-Resource Language ProcessingMultimodal LearningMultimodal Understanding
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May 16, 2026

Controlling Decision Drift in Multimodal Sentiment Analysis with Missing Modalities

Multimodal sentiment analysis relies on textual, acoustic, and visual signals, yet real-world data often suffer from modality missing and quality imbalance. Existing methods generate features for modality missing from available ones, but differences in expression mechanisms and sentiment dynamics across modalities may cause the generated features to deviate from true distributions and mislead prediction. In addition, unreliable modalities may dominate fusion, resulting in representation shift across modality combinations and unstable sentiment representations. To address these challenges, we propose a two-level reference alignment framework. The framework introduces stable references at the feature representation and sentiment decision levels to improve robustness under modality missing. First-level reference alignment leverages complete-modality samples to constrain representations and align different modality combinations into a shared sentiment space. Second-level reference alignment enforces cross-modal consistency at the decision level by suppressing unreliable modalities through prototype retrieval and voting. As a result, the framework maintains stable and reliable sentiment predictions under diverse missing-modality patterns. Experiments on CMU-MOSI and CMU-MOSEI show consistent improvements across various missing-modality settings. Under full-modality input, the proposed method achieves state-of-the-art performance, with ACC of 86.28% and 85.88%, and F1 of 86.24% and 85.86%.

Chenglizhao Chen, Yuchen Cao, Xinyu Liu +3

Qingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China) · Shandong Key Laboratory of Intelligent Oil & Gas Industrial Software · The Hong Kong University of Science and Technology (Guangzhou)

Missing-Modality LearningMultimodal RobustnessCross-Modal AlignmentSentiment AnalysisMultimodal Sentiment Analysis
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May 16, 2026

Learning Relative Representations for Fine-Grained Multimodal Alignment with Limited Data

Multimodal pre-training demonstrates strong generalization performance, but this paradigm is often impractical in domains where paired data are scarce. A promising alternative is post-hoc multimodal alignment, which aligns separately pre-trained unimodal encoders using a limited number of paired examples. However, existing methods focus primarily on aligning global representations, missing patch-token relations. This may hinder transfer to tasks that require fine-grained cross-modal matching beyond coarse sample-level semantics. To address this issue, we propose a post-hoc alignment method that learns token-level cross-modal structure using relative representations. Specifically, we represent images and texts through their token-level similarities to a set of learnable anchors in each modality space, which are trained to induce consistent cross-modal similarity patterns for matched pairs. Despite learning only the anchors without heavy projection layers, our approach consistently outperforms existing methods in zero-shot classification, cross-modal retrieval, and zero-shot segmentation by a substantial margin. This highlights the importance of modeling fine-grained cross-modal structure for effective post-hoc multimodal alignment with limited paired data.

Shiwon Kim, Yu Rang Park

Yonsei University

Cross-Modal LearningRepresentation LearningCross-Modal Representation LearningCross-Modal AlignmentCross-Modal Feature Matching
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May 16, 2026

Cross-modal Affinity-aligned Multimodal Learning Analytics for Predicting Student Collaboration Satisfaction in Game-Based Learning

Collaborative game-based learning environments offer rich opportunities for small-group knowledge construction, yet automatically predicting student collaboration satisfaction remains challenging. A critical barrier is modality degradation: in educational deployments, individual modalities such as eye gaze exhibit inconsistent informativeness across student cohorts, causing implicit attention-based fusion to produce brittle multimodal representations. We propose the Affinity-Aligned Multimodal Learning Analytics (AAMLA) framework, whose core contribution is the Cross-modal Affinity-guided Modality Alignment (CAMA) module, which explicitly models inter-modal relationships via affinity matrices and enforces cross-modal consistency through contrastive learning, enabling adaptive suppression of uninformative modalities without discarding them. AAMLA further applies modality-specific projection layers to map heterogeneous features, including facial action units, head pose, eye gaze, and interaction trace logs, into a unified semantic space prior to alignment. Experiments on 50 middle school students in the EcoJourneys collaborative learning environment demonstrate consistent improvements over unimodal baselines and prior cross-attention approaches under standard and modality degradation conditions, with SHAP and t-SNE analyses confirming that CAMA produces robust, interpretable cross-modal representations for student collaboration modeling.

Wen-Hsin Tsai, Chia-Ming Lee, Yuk-Ying Tung

Institute of Education, National Cheng Kung University · Institute of Intelligent System, National Yang Ming Chiao Tung University · Department of Computer Science, University at Albany, State University of New York

Cross-Modal LearningMultimodal RobustnessCross-Modal AlignmentEducational TechnologyGame-Based LearningMultimodal Contrastive Learning+1
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May 16, 2026

Cross-Domain Molecular Relational Learning: Leveraging Chemical Structure-Activity Analysis

Recent advances in molecular representation integrates molecular topological and visual modalities, opening new avenues for precise Molecular Relational Learning (MRL). Existing MRL methods focus on intra-domain modeling, and their inherent domain-closed effect limits applicability to molecular science, particularly in elucidating cross-domain interaction mechanisms. Consequently, the imperative for Cross-Domain Molecular Relational Learning has become increasingly pressing. Benefiting from structure-activity analysis, we propose the Domain Adversarial Training Network with Structural-Semantic Transfer Discrepancy (DisTrans) to optimize cross-domain adaptive representation for molecular structures and visual images. 1) We employ the gradient reversal strategy based on substructure topological discrepancies between domains to learn the domain dependence of molecular structures. This strategy guides the model to adapt to the structural adjacency patterns in the target domain, generating domain-separable structural representations. 2) We apply the cross-domain representation guidance mechanism to align the functional-group semantic information between the source and target domains, learning cross-domain consistency information. The experimental results in two typical cross-domain strategies demonstrate that DisTrans outperforms 16 baseline methods, maintaining satisfactory performance even under pronounced inter-domain discrepancy.

Peiliang Zhang, Jingling Yuan, Shiqing Wu +4

Wuhan University of Technology Wuhan, Hubei, China · Hubei Key Laboratory of Transportation Internet of Things State Key Laboratory of Silicate Materials for Architectures Wuhan University of Technology Wuhan, Hubei, China · Yonsei University Seoul, Republic of Korea +3

Domain-Adversarial LearningCross-Modal Representation LearningUnsupervised Domain AdaptationCross-Modal AlignmentMolecular Representation Learning
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May 15, 2026

Controlla: Learning Controllability via Graph-Constrained Latent Geometry

Controllable multimodal generation is commonly formulated as an inference-time conditioning problem using prompts, guidance, or auxiliary modules. While effective, such approaches do not explicitly structure how semantic attributes evolve, which can lead to identity drift and inconsistent cross-modal behavior. We propose Controlla, a modular factorized-control framework that treats controllability as a property of structured latent geometry. Controlla learns identity and attribute factors from multimodal inputs and aligns them with graph priors using graph-constrained optimal transport, encouraging attributes to follow graph-consistent trajectories while preserving reference identity. To evaluate this setting, we construct AffectHuman-43K, a leakage-aware multimodal benchmark for reference-grounded affective control, and introduce geometry-aware metrics for trajectory consistency and latent disentanglement. Experiments show consistent improvements in controllability, identity preservation, and cross-modal alignment, with additional analyses on graph sensitivity, extensibility, and robustness.

Jamuna S. Murthy, Amin Karimi Monsefi, Rajiv Ramnath

Ramaiah Institute of Technology · The Ohio State University

Disentangled Representation LearningMultimodal Disentangled Representation LearningCross-Modal AlignmentMultimodal Generation
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May 15, 2026

SOLAR: Self-supervised Joint Learning for Symmetric Multimodal Retrieval

In this work, we address the critical yet underexplored challenge of symmetric multimodal-to-multimodal (MM2MM) retrieval, where queries and contexts are interchangeable. Existing universal multimodal retrieval works struggle with this task, as they are constrained by the labeled asymmetric datasets used. We produce SOLAR (Self-supervised jOint LeArning for symmetric multimodal Retrieval), a novel two-stage self-supervised framework that leverages readily available unlabeled web-scale image-text pairs. Based on the observation that both semantic alignment and discrepancies exist between two modalities, in the first stage, we learn the intersection mask of image-text pair, allowing us to align intersection while preserving semantic of difference. In the second stage, the learned mask is further utilized to construct positive and hardnegative samples via masking different parts of image/text, which enable us to conduct self-supervised multimodal embedding learning. Complementing this framework, we present a new benchmark featuring high-quality human-verified positive and hard-negative pairs to evaluate symmetric MM2MM retrieval under realistic conditions, as well as the corresponding pipeline. Extensive experiments against ten SOTA methods show SOLAR surpasses the strongest supervised VLM by 7.08 points on this benchmark, with over 50x fewer model parameters and a 5x smaller embedding dimension. Code, model and benchmark are available at https://github.com/codefuse-ai/SOLAR.

Wenjie Yang, Hang Yu, Yuyu Guo +1

Ant Group

Cross-Modal LearningMultimodal IRSelf-Supervised LearningCross-Modal AlignmentMultimodal EmbeddingCross-Modal Retrieval+1
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May 15, 2026

Cross-Modal Registration Between 3D and 2D Fingerprints via Pose-Aware Unwrapping and Point-Cloud Fusion

Three-dimensional (3D) fingerprints preserve global finger geometry and local ridge structure while avoiding contact-induced deformation, but they remain difficult to integrate with legacy two-dimensional (2D) fingerprint systems. This paper addresses the intermediate stage between 3D acquisition and cross-modal matching, and presents a unified framework for 3D fingerprint preprocessing and registration across contactless and contact-based 2D modalities. The framework combines four components: 1) a nonparametric visualization and unwrapping method that converts a 3D fingerprint point cloud into a rolled-equivalent 2D representation without relying on a global finger-shape model; 2) a point-cloud fusion pipeline that registers and mosaics multiple partial 3D captures into a more complete fingerprint model; 3) an ellipse-based pose normalization method for canonical finger alignment; and 4) a pose-aware cross-modal registration strategy that improves compatibility between 3D fingerprints and both contactless and contact-based 2D fingerprints. Experiments on a self-collected multimodal fingerprint database containing 150 fingers show that the proposed framework achieves ridge-level 3D registration accuracy, robust pose estimation, and consistent gains in 2D compatibility. In particular, the 3D fusion error is concentrated around 0.09 mm, contactless 2D--3D registration reaches ridge-scale projection accuracy, and pose-aware unwrapping improves genuine matching scores relative to generic 3D unwrapping. These results support the use of 3D fingerprints as an effective geometric bridge across heterogeneous fingerprint modalities. The baseline implementation has been publicly released at https://github.com/XiongjunGuan/3DFpVisual.

Xiongjun Guan, Jianjiang Feng, Jie Zhou

Department of Automation, Tsinghua University, Beijing 100084, China

Biometric IdentificationCross-Modal AlignmentPoint Cloud RegistrationFingerprint Identification
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May 15, 2026

GOMA: Toward Structure-Driven Multimodal Alignment from a Graph Signal Smoothing Perspective

Multimodal retrieval uses images, text, and object relationships to answer different questions about the same collection. A query may seek an object's paired description, another object in the same category, or an object connected by an observed relationship. These goals rely on different notions of relevance. Paired matching requires object-specific distinctions, whereas cross-object retrieval benefits from relational agreement. Existing methods learn strong cross-modal correspondence or propagate information over a graph, but a shared output regularized toward neighbors can weaken identity distinctions. Moreover, gains from graph regularization can diminish after uniform graph propagation. We introduce Graph-Optimized Multimodal Alignment (GOMA), which assigns these roles to two connected embeddings. Each modality produces a content embedding directly supervised for paired identity and a semantic embedding jointly trained with cross-modal pairs and observed relationships. For complete records, both embeddings form an initial fused representation, semantic agreement sets positive weights on observed edges, and restart graph propagation reinjects this initial signal. This design lets a jointly trained model support single-modality and dual-attribute retrieval through a task-specific readout. Across six datasets and four tasks, GOMA achieves state-of-the-art performance on all 14 primary measures against 14 external methods. Controlled comparisons further show how separate supervision, graph regularization, and semantic-guided graph propagation shape the final representation and align the learned signal with each retrieval target.

Xu Wang, Xunkai Li, Yinlin Zhu +2

School of Airspace Science and Engineering, Shandong University, WeiHai, China · Department of Computer Science, Beijing Institute of Technology, Beijing, China · School of Computer Science and Engineering, Sun Yat-sen University, GuangZhou, China

Cross-Modal LearningMultimodal IRGraph Signal ProcessingCross-Modal AlignmentMultimodal EmbeddingCross-Modal Retrieval+1
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May 15, 2026

Semi-MedRef: Semi-Supervised Medical Referring Image Segmentation with Cross-Modal Alignment

Medical referring image segmentation (MRIS) requires pixel-level masks aligned with textual descriptions of anatomical locations, making annotation costly in low-label regimes. Semi-supervised learning (SSL) can mitigate this burden by leveraging unlabeled data, but its success hinges on maintaining reliable image-text alignment under perturbations. Most existing SSL-based referred segmentation methods use either independent or simplistic multi-modal perturbations (e.g., left-right flips), without fully addressing cross-modal alignment under strong augmentation, while CutMix, highly effective in single-modal SSL, remains underexplored in multi-modal settings due to its tendency to disrupt image-text coherence. We propose Semi-MedRef, a teacher-student SSL framework designed to explicitly maintain consistency between medical images and positional language through three alignment-preserving components: T-PatchMix, a cross-modal CutMix-style augmentation that synchronizes patch mixing with referring expressions via position-constrained and probability-driven rules; PosAug, a position-aware text augmentation that masks or fuzzes anatomical phrases; and ITCL, a position-guided image-text contrastive learning module, which leverages positional pseudo-labels to construct soft anatomical positives and strengthen medically grounded cross-modal alignment. Experiments on QaTa-COV19 and MosMedData+ demonstrate that Semi-MedRef consistently outperforms both fully supervised and semi-supervised baselines across all label regimes.

Yuchen Li, Zhen Zhao, Yi Liu +1

The University of Sydney, Sydney, NSW 2006, Australia · Shanghai Artificial Intelligence Laboratory, Shanghai, China · Changzhou University, Changzhou, China

Interactive Medical Image SegmentationCross-Modal AlignmentReferring Image SegmentationSemi-Supervised Medical Image SegmentationMedical Image SegmentationMultimodal Contrastive Learning
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May 14, 2026

Text Knows What, Tables Know When: Clinical Timeline Reconstruction via Retrieval-Augmented Multimodal Alignment

Clinical language models increasingly operate over electronic health records (EHRs), yet patient records are not stored as temporally grounded trajectories. Clinical notes describe symptoms, assessments, and disease progression, but often compress or narratively reorder events. Structured EHR rows provide timestamps for labs, medications, vitals, and procedures, but capture only part of the clinical story. We formulate clinical timeline reconstruction as retrieval-augmented temporal grounding: constructing a patient trajectory by using narrative text for event semantics and structured rows as partial temporal evidence. We introduce a scaffolded workflow that extracts central narrative events, builds an initial temporal scaffold, attaches non-central events, and calibrates timestamps using retrieved structured EHR rows. We evaluate on 40 discharge summaries, including 15 i2b2-derived and 25 MIMIC-IV summaries, each with manual gold-standard timelines and aligned structured EHR data. Across models, multimodal calibration left event match rates largely unchanged and generally improved temporal performance: mean paired case-level multimodal-unimodal differences were positive in 7 of 12 model-metric comparisons across concordance and AULTC, with none negative. However, uncertainty was substantial given the 40-case sample; paired case-level bootstrap intervals excluded zero only for the DeepSeek V3.2 AULTC improvement. A gap analysis shows that 35.1% of text-derived events have no structured counterpart. These findings support treating structured EHR data as partial temporal evidence for narrative-derived patient trajectories.

Sayantan Kumar, Shahriar Noroozizadeh, Juyong Kim +1

Division of Intramural Research National Library of Medicine, National Institutes of Health Bethesda, MD, USA

Multimodal RAGHealthcareCross-Modal AlignmentLongitudinal EHR ModelingElectronic Health Records
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May 14, 2026

Vision-Core Guided Contrastive Learning for Balanced Multi-modal Prognosis Prediction of Stroke

Deep learning and multi-modal fusion have demonstrated transformative potential in medical diagnosis by integrating diverse data sources. However, accurate prognosis for ischemic stroke remains challenging due to limitations in existing multi-modal approaches. First, current methods are predominantly confined to dual-modal fusion, lacking a framework that effectively integrates the trifecta of medical images, structured clinical data, and unstructured text. Second, they often fail to establish deep bidirectional interactions between modalities; To address these critical gaps, this paper proposes a novel tri-modal fusion model for ischemic stroke prognosis. Our approach first enriches the data representation by employing a Large Language Model (LLM) to automatically generate semi-structured diagnostic text from brain MRIs. This process not only addresses the scarcity of expert annotations but also serves as a regularized semantic enhancement, improving multimodal fusion robustness. Furthermore, we design a core component termed the Vision-Conditioned Dual Alignment Fusion Module (VDAFM), which strategically uses visual features as a conditional prior to guide fine-grained interaction with the generated text. This module achieves a dynamic and profound fusion through a dual semantic alignment loss, effectively mitigating modal heterogeneity. Extensive experiments on a real-world clinical dataset demonstrate that our model achieves state-of-the-art performance.

Liren Chen, Lidong Sun, Mingyan Huang +5

School of Information Science and Engineering, East China University of Science and Technology, Shanghai, 200237, PR China

Cross-Modal AlignmentClinical Outcome PredictionMultimodal Contrastive LearningMultimodal Fusion
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May 14, 2026

Beyond Instance-Level Self-Supervision in 3D Multi-Modal Medical Imaging

Self-supervised pre-training methods in medical imaging typically treat each individual as an isolated instance, learning representations through augmentation-based objectives or masked reconstruction. They often do not adequately capitalize on a key characteristic of physiological features: anatomical structures maintain consistent spatial relationships across individuals (instances), such as the thalamus being medial to the basal ganglia, regardless of variations in brain size, shape, or pathology. We propose leveraging this cross-instance topological consistency as a supervisory signal. The challenge arises from the inherent variability in medical imaging, which can differ significantly across instances and modalities. To tackle this, we focus on two alignment regimes. (i) Intra-instance: with pixel-level correspondences available, a cross-modal triplet objective explicitly preserves local neighborhood topology. (ii) Inter-instance: without such supervision, we derive pseudo-correspondences to control partial neighborhood alignment and prevent topology collapse across modalities. We validate our approach across 7 downstream multi-modal tasks, achieving average improvements of 1.1% and 5.94% in segmentation and classification tasks, respectively, and demonstrating significantly better robustness when modalities are missing at test time.

Tan Pan, Shuhao Mei, Yixuan Sun +8

Fudan University, China · Shanghai Academy of AI for Science, China · Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore +2

Representation LearningMultimodal RobustnessSelf-Supervised Pre-TrainingCross-Modal AlignmentMedical Image SegmentationTopological Representation Learning
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May 14, 2026

UniTriGen: Unified Triplet Generation of Aligned Visible-Infrared-Label for Few-Shot RGB-T Semantic Segmentation

RGB-T semantic segmentation requires strictly aligned VIS-IR-Label triplets; however, such aligned triplet data are often scarce in real-world scenarios. Existing generative augmentation methods usually adopt cascaded generation paradigms, decomposing joint triplet generation into local conditional processes. As a result, consistency among VIS, IR, and Label in spatial structure, semantic content, and cross-modal details cannot be reliably maintained. To address this issue, we propose UniTriGen, a unified triplet generation framework that directly generates spatially aligned, semantically consistent, and modality complementary VIS-IR-Label triplets under the guidance of text prompts. UniTriGen first introduces a unified triplet generation mechanism, where VIS, IR, and Label are jointly encoded into a shared latent space and modeled with a diffusion process to enforce global cross-modal consistency. Lightweight modality-specific residual adapters are further integrated into this mechanism to accommodate modality-specific imaging characteristics and output formats. To mitigate generation bias caused by imbalanced scene and class distributions in limited paired triplets, UniTriGen also employs a scene-balanced and class-aware few-shot sampling strategy, which induces a more balanced sampling distribution and enhances the scene and class diversity of generated triplets. Experiments show that UniTriGen generates high-quality aligned triplets from limited real paired data, thereby achieving consistent performance improvements across various RGB-T semantic segmentation models.

Ping Zhou, Haoyu Wang, Mengmeng Zheng +4

School of Computer Science, Northwestern Polytechnical University · School of Computer Science & Technology, Xi’an University of Posts & Telecommunications · MMLab, The Chinese University of Hong Kong

Cross-Modal AlignmentMultimodal GenerationDiffusion-Based Image GenerationSemantic Segmentation
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May 14, 2026

Neural Visual Decoding via Cognitive guided Adaptive Blurring and Information Constrained Alignment

EEG-based visual decoding aims to establish a mapping between neural signals and visual semantics. However, it remains constrained by the dual challenges of severe information granularity mismatch and the low signal-to-noise ratio (SNR) of EEG signals. Existing approaches typically treat visual features as static, ignoring the dynamic selectivity of human vision and the frequency specificity of neural oscillations. To bridge this gap, we propose CAIA, a Cognitive-guided Adaptive blurring with Information-Constrained Alignment framework for Neural-Visual decoding. On the visual side, it simulates selective attention to adaptively reduce redundancy. Meanwhile, on the EEG side, it combines neural oscillation priors with an information-bottleneck-inspired spectral sparsity regularizer to enhance SNR. Specifically, we devise a cognitive-dynamics-based adaptive blurring mechanism that dynamically integrates center-biased and saliency-guided visual cues via cross-modal attention. Furthermore, we introduce a distribution-aware boundary calibration loss to robustly rectify alignment bias caused by outlier samples. Moreover, a cognitively guided information-screening method is proposed to select task-relevant EEG oscillations. Extensive experiments demonstrate that CAIA improves both subject-dependent and subject-independent average Top-1 and Top-5 accuracy in zero-shot brain-to-image retrieval, significantly outperforming prior methods. Our work validates that optimizing visual information density to match neural granularity offers a more interpretable and robust pathway for neural decoding.

Fan Yin, Chuhang Zheng, Peiliang Gong +2

Department of Artificial Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China · Department of Electrical and Information Engineering, Tianjin University, Tianjin, China

EEG-Based Visual DecodingCross-Modal AlignmentCross-Modal Retrieval
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May 14, 2026

Let Robots Feel Your Touch: Visuo-Tactile Cortical Alignment for Embodied Mirror Resonance

Observing touch on another's body can elicit corresponding tactile sensations in the observer, a phenomenon termed mirror touch that supports empathy and social perception. This visuo-tactile resonance is thought to rely on structural correspondence between visual and somatosensory cortices, yet robotic systems lack computational frameworks that instantiate this principle. Here we demonstrate that cortical correspondence can be operationalized to endow robots with mirror touch. We introduce Mirror Touch Net, which imposes semantic, distributional and geometric alignment between visual and tactile representations through multi-level constraints, enabling prediction of millimetre-scale tactile signals across 1,140 taxels on a robotic hand from RGB images. Manifold analysis reveals that these constraints reshape visual representations into geometry consistent with the tactile manifold, reducing the complexity of cross-modal mapping. Extending this alignment framework to cross-domain observations of human hands enables tactile prediction and reflexive responses to observed human touch. Our results link a neural principle of visuo-tactile resonance to robotic perception, providing an explainable route towards anticipatory touch and empathic human-robot interaction. Code is available at https://github.com/fun0515/Mirror-Touch-Net.

Tianfang Zhu, Ning An, Rui Wang +4

Institute for AI Industry Research, Tsinghua University, Beijing, China. · MoE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, China. · School of New Media Art and Design, Beihang University, Beijing, China. +1

Vision-Based Tactile SensingVisual-to-Tactile PredictionCross-Modal AlignmentRobotic Tactile SensingRobotic Perception
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May 13, 2026

PRA-PoE: Robust Multimodal Alzheimer's Diagnosis with Arbitrary Missing Modalities

Missing modalities are prevalent in real-world Alzheimer's disease (AD) assessment and pose a significant challenge to multimodal learning, particularly when the distribution of observed modality subsets differs between training and deployment. Such missingness pattern mismatch induces a conditional representation shift across modality subsets. Existing approaches that rely on implicit imputation or modality synthesis often fail to explicitly model modality availability and uncertainty, leading to overconfident dependence on synthesized features, reduced robustness, and miscalibrated uncertainty estimates. To address these limitations, we propose PRA-PoE, an incomplete multimodal learning framework that is equipped with Prototype-anchored Representation Alignment (PRA) and an Uncertainty-aware Product of Experts (UA-PoE) fusion mechanism. First, PRA uses learnable global prototypes and availability-conditioned tokens to encode modality availability, distinguish observed from missing modalities, re-synthesize features for missing modalities, and adaptively refine observed representations to align latent spaces across modality subsets, with the goal of reducing representation shift under varying missingness patterns. Second, UA-PoE models each modality as a Gaussian expert and performs closed-form Product of Experts fusion, where experts with higher uncertainty are automatically down-weighted via lower precision, improving uncertainty reliability. We evaluate PRA-PoE under a clinically realistic protocol by training with naturally missing data and testing on all non-empty modality combinations. PRA-PoE consistently outperforms the state-of-the-art across datasets, achieving a 5.4% relative improvement in average accuracy on ADNI and a 10.9% relative gain in average F1 on OASIS-3 over the strongest baseline across all non-empty modality subsets.

Guangqian Yang, Ye Du, Wenlong Hou +2

Department of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong SAR, China · Department of Technology Management for Innovation, The University of Tokyo,2026 Japan · Department of Data Science and Artificial Intelligence, The Hong Kong Polytechnic University, Hong Kong SAR, China

Missing-Modality LearningAlzheimer's DiseaseMultimodal RobustnessMedical DiagnosisCross-Modal AlignmentLearning with Missing Data+2
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May 13, 2026

SMA: Submodular Modality Aligner For Data Efficient Multimodal Learning

Despite the recent success of Multimodal Foundation Models (FMs), their reliance on massive paired datasets limits their applicability in low-data and rare-scenario settings where aligned data is scarce and expensive. A key bottleneck is the adoption of an instance-level formulation, which learns alignment by maximizing correlation between individual image-text pairs while neglecting the underlying geometric structure across modalities resulting in a modality gap across input modalities. In this paper, we propose a combinatorial paradigm for multimodal alignment that moves beyond pairwise learning and introduce the Submodular Modality Aligner (SMA), which treats multiple augmentations and descriptions of an entity as a set, leveraging multiple descriptions of the data to capture richer cross-modal structure. We instantiate SMA using a principled objective based on Submodular Mutual Information (SMI), which jointly maximizes inter-modality mutual information while reducing cross-modal divergence. This formulation enables the model to effectively utilize multiple positive associations and extract significantly more information from limited data. We evaluate SMA on 14 zero-shot classification and retrieval tasks from the CLIP benchmark and demonstrate consistent gains in the low-data regime. Notably, SMA achieves strong multimodal generalization using only tens of thousands of samples. This is orders of magnitude fewer than standard approaches. Our results highlight the importance of set-based formulations and submodular objectives for data-efficient multimodal learning.

Truong Pham, Anay Majee, Rishabh Iyer

The University of Texas at Dallas

Cross-Modal LearningCross-Modal AlignmentMultimodal Foundation ModelsMultimodal Contrastive LearningData-Efficient LearningMultimodal Understanding
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May 12, 2026

Lifelong Learning in Vision-Language Models: Enhanced EWC with Cross-Modal Knowledge Retention

Large language-vision models (LVLMs) such as CLIP, Flamingo, and BLIP have revolutionized AI by enabling understanding across textual and visual modalities. These models excel at tasks like image captioning, visual question answering, and cross-modal retrieval. However, they face catastrophic forgetting when learning new tasks sequentially, particularly challenging in multi-modal settings where preserving cross-modal alignments adds complexity to the learning process. This paper presents a comprehensive continual learning framework for LVLMs that combines enhanced Elastic Weight Consolidation (EWC) with parameter-efficient fine-tuning techniques. We integrate multi-modal Fisher Information Matrix calculation, consistency preservation across modalities, and adaptive regularization that considers dependencies across visual and textual encoders. The framework achieves a 78% reduction in forgetting rates relative to naive sequential training approaches through extensive evaluation testing. The framework also preserves alignment between modalities during sequential learning with only 15% additional computational cost. This work advances the state of the art in lifelong learning for multi-modal AI systems, with direct applications to autonomous driving, intelligent robotic assistants, and adaptive robotic systems that must continuously learn in dynamic real-world environments.

Hamza Ahmed Durrani, Rafay Suleman Durrani

Sejong University, Computer Science Engineering · Technische Universität Ilmenau, Computer Engineering

Vision-Language ModelsCross-Modal AlignmentElastic Weight ConsolidationContinual Learning for VLMs
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May 12, 2026

Cross-Modal-Domain Generalization Through Semantically Aligned Discrete Representations

Multimodal learning seeks to integrate information across diverse sensory sources, yet current approaches struggle to balance cross-modal generalizability with modality-specific structure. Continuous (implicit) methods preserve fine-grained priors but render generalization challenging, while discrete (explicit) approaches enforce shared prototypes at the expense of modality specificity. We introduce CoDAAR (Cross-modal Discrete Alignment And Reconstruction), a novel framework that resolves this long-standing trade-off by establishing semantic consensus across modality-specific codebooks through index-level alignment. This design uniquely allows CoDAAR to preserve modality-unique structures while achieving generalizable cross-modal representations within a unified discrete space. CoDAAR combines two complementary mechanisms: Discrete Temporal Alignment (DTA), which enables fine-grained temporal quantization, and Cascading Semantic Alignment (CSA), which promotes progressive cross-modal semantic agreement. Together, they establish a competition-free unified representation space. Trained with self-supervised reconstruction objectives on paired multimodal sequences, CoDAAR demonstrates robust cross-modal and cross-domain generalization. Across Cross-Modal Generalization benchmarks, including event classification, localization, video segmentation, and cross-dataset transfer, CoDAAR achieves state-of-the-art performance, establishing a new paradigm for discrete and generalizable multimodal representation learning.

Souptik Sen, Raneen Younis, Zahra Ahmadi

Peter L. Reichertz Institute for Medical Informatics, Hannover Medical School, Germany · Lower Saxony Center for AI and Causal Methods in Medicine (CAIMed), Hannover, Germany

Multimodal LearningRepresentation LearningCross-Modal Representation LearningMultimodal Domain GeneralizationCross-Modal AlignmentMultimodal SSL+3
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May 12, 2026

Towards Visually Grounded Multimodal Summarization via Cross-Modal Transformer and Gated Attention

Multimodal summarization requires models to jointly understand textual and visual inputs to generate concise, semantically coherent summaries. Existing methods often inject shallow visual features into deep language models, leading to representational mismatches and weak cross-modal grounding. We propose a unified framework that jointly performs text summarization and representative image selection. Our system, SPeCTrA-Sum (Sampler Perceiver with Cross-modal Transformer and gated Attention for Summarization), introduces two key innovations. First, a Deep Visual Processor (DVP) aligns the visual encoder with the language model at corresponding depths, enabling hierarchical, layer-wise fusion that preserves semantic consistency. Second, a lightweight Visual Relevance Predictor (VRP) selects salient and diverse images by distilling soft labels from a Determinantal Point Processes (DPP) teacher. SPeCTrA-Sum is trained using a multi-objective loss that combines autoregressive summarization, cross-modal alignment, and DPP-based distillation. Experiments show that our system produces more accurate, visually grounded summaries and selects more representative images, demonstrating the benefits of depth-aware fusion and principled image selection for multimodal summarization.

Abid Ali, Diego Molla-Aliod, Usman Naseem

School of Computing, Macquarie University, Sydney, Australia

Cross-Modal AlignmentDeterminantal Point ProcessMultimodal GenerationMultimodal Fusion
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May 12, 2026

TB-AVA: Text as a Semantic Bridge for Audio-Visual Parameter Efficient Finetuning

Audio-visual understanding requires effective alignment between heterogeneous modalities, yet cross-modal correspondence remains challenging when temporally aligned audio and visual signals lack clear semantic correspondence. We propose to use text as a semantic anchor for audio-visual representation learning. To this end, we introduce a parameter-efficient adaptation framework built on frozen audio and visual encoders, centered on Text-Bridged Audio-Visual Adapter (TB-AVA), which enables text-mediated interaction between audio and visual streams. At the core of TB-AVA, Gated Semantic Modulation (GSM) selectively modulates feature channels based on text-inferred semantic relevance. We evaluate the proposed approach on multiple benchmarks, including AVE, AVS, and AVVP, where the proposed framework achieves state-of-the-art performance, demonstrating text as an effective semantic anchor for parameter-efficient fine-tuning (PEFT) in audio-visual learning.

Seongah Kim, Dinh Phu Tran, Hyeontaek Hwang +3

AI2 Lab, KAIST

Audio-Visual UnderstandingAudio-Visual Representation LearningCross-Modal AlignmentAdapter TuningParameter-Efficient Fine-Tuning
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