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31 papers in the last four weeks, down 11% on the four weeks before. 0.4% of all new papers.

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Latest papers 284

Jul 10, 2026stat.ML

Influence Diagnostics in High-dimensional M-estimation: Precise Asymptotics

The impact of a given training point on a statistical model is classically measured through its leave-one-out influence, which quantifies the effect of its removal from the training set on the model accuracy. While the statistics of leave-one-out influences are well understood in the low-dimensional, large sample limit

n\to \infty, d=O(1)

, they become more intricate in high dimensions, as the influence of a given sample develops non-trivial dependencies on all other training samples. For convex M-estimation under Gaussian design, in the high-dimensional limit

n\asymp d

, we show that the distribution of the influences across the training set converges to a limiting measure which we sharply characterize. Building on these results, we provide evidence that influential samples tend to lie close to the decision boundary, thereby making contact with a standard data selection heuristic in active learning.

Hugo Cui

Université Paris-Saclay, CNRS, Laboratoire de mathématiques d’Orsay, 91405, Orsay, France

Influence Function High-Dimensional Influence Decision Boundaries Finite Time Analysis Active Learning+1

Jul 9, 2026cs.AI

A safety-oriented hypothetico-deductive framework for AI-assisted differential diagnosis

Diagnostic error is a major threat to patient safety, yet current large language model (LLM) systems often treat diagnosis as a one-shot prediction task, lacking safeguards against missed high-risk alternatives or rigorous verification of their reasoning. Here, we present AegisDx, a safety-oriented framework for hypothetico-deductive clinical reasoning. AegisDx coordinates specialized LLM components through role-specific contracts, structured intermediate outputs, evidence-retrieval interfaces, and verification gates to generate broad differential diagnoses, enforce explicit screening for dangerous "must-not-miss" conditions, verify reasoning against grounded medical evidence, and structure actionable next steps. We evaluated AegisDx across three layers. On literature-derived case reports from NEJM and JAMA, with GPT-oss-120B as the shared backbone, Top-3 diagnostic accuracy was 59.9% versus 52.1% for the standalone LLM on JAMA cases and 62.7% versus 51.4% on NEJM cases. On cases from Annals of Emergency Medicine, Top-3 accuracy was 85.7% versus 68.6%; against physician-consensus must-not-miss diagnosis sets, AegisDx captured at least one such condition among its top three diagnoses in 78.0% of cases versus 52.0%. In a blinded physician evaluation of 43 real-world emergency department notes from the Yale New Haven Health System compared against GPT-5, AegisDx improved the physician-rated composite safety score from 4.31 to 4.55 on a 5-point scale (adjusted p = 2.1x10^-4), with qualitative gains in must-not-miss identification and reasoning safety. Our findings suggest that engineering diagnostic AI as a safety-oriented reasoning framework, rather than optimizing raw predictive accuracy alone, can provide a safer, more transparent, and clinically meaningful layer of bedside decision support for acute care workflows.

Fan Ma, Mauro Giuffrè, Donald Wright +12

Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, USA · Department of Medical, Surgical and Health Sciences, Università degli Studi di Trieste, Trieste, Italy · Department of Emergency Medicine, Yale School of Medicine, Yale University, New Haven, USA +3

Clinical Reasoning Training Diagnosis

Jul 8, 2026cs.AI

Aligning Clinical Needs and AI Capabilities: A Survey on LLMs for Medical Reasoning

Large language models (LLMs) have emerged as important tools in healthcare, showing growing potential for clinical reasoning and patient care. This survey examines recent progress in medical LLMs, focusing on reasoning applications and requirements. We present a dual-view approach that connects clinical practice with computational methods. On the clinical side, we establish a five-level competency scheme following Miller's Pyramid, progressing from knowledge recall to dynamic case management. On the computational side, we link deductive, inductive, and abductive reasoning patterns to common medical goals and tasks. We also introduce a benchmark dataset spanning five levels of medical reasoning capability and report results on 18 state-of-the-art models, revealing that medical specialist models excel in diagnosis-centric tasks while general models lead in decision support and dialogue. We conclude by discussing current progress and open challenges, including data limitations, hallucination, and grounding issues, and outline directions toward safer, more reliable, and workflow-ready systems.

Qi Peng, Jiatong Li, Sirui Huang +10

1The Hong Kong Polytechnic University, Hong Kong, China. · 2Hong Kong University, Hong Kong, China. · 3South China University of Technology, Guangzhou, China. +3

Clinical Reasoning Training LLM Reasoning Strategies Reasoning Skills Diagnosis Abductive Reasoning Artificial Intelligence Systems

Jul 8, 2026cs.LG

A Transdiagnostic Space of Disorder Like Phenotypes in Reinforcement Learning Agents

Modelling psychological disorders in artificial agents offers both a testbed for computational psychiatry and a lens on the failure modes of affective control. Prior work induces one or two disorders in a reinforcement learning (RL) agent by hand-tuned reward shaping, labels the behaviour post hoc, and reports single runs. We recast disorder modelling as dose-controllable manipulation of cognitive appraisal signals in an appraisal-guided PPO agent, expressing seven disorders (anxiety, mania, obsessive-compulsive checking, depression, impulsivity, addiction, and post-traumatic stress) each as a single knob grounded in a computational psychiatry account, with each symptom measured by a preregistered assay mapped to a recognised paradigm. Across more than a thousand runs (10 seeds, four controls, 95% confidence intervals) every disorder shows a graded, monotone dose-response that no control reproduces. Beyond these induced effects, three findings emerge that were not written into the reward: the disorders self-organise into a two-dimensional affective space in which mania mirrors anxiety; removing a knob remits reward distortion disorders (mania, checking, addiction) but not avoidance disorders (anxiety, PTSD), which instead recover under a graded exposure curriculum; and two simultaneous knobs interact nonadditively, yielding testable comorbidity predictions. Appraisal weights thus parameterise a controllable space of affective phenotypes in which the same knobs that induce a disorder can model its treatment. We also show that three disorder knobs (depression, addiction, anxiety) transfer to a three-dimensional pixel environment (MiniWorld) with a standard convolutional agent and no appraisal critic, with cross-assay dissociation confirmed across both domains, indicating the framework is not specific to grid worlds or to PPO's appraisal critic.

Hari Prasad

Offline Reinforcement Learning Mental Health Phenotypes Diagnosis

Jul 7, 2026cs.RO

Imagined Rollouts are Kinematic, Not Dynamic: A Diagnosis of Long-Horizon World-Model Failure

Long-horizon failure in world models is conventionally attributed to compounding error, a generic framing that does not distinguish what kind of error compounds. We propose a kinematic-vs-dynamic reframing: world models tend to imagine kinematically rather than dynamically. We operationalize this as the imagined Kinematic-Consistency Error, a per-step diagnostic that measures how far a rollout departs from a closed-form kinematic null, paired with a perturbation protocol that tests whether iKCE responds when physical conditions cross a regime boundary. We instantiate the diagnostic on a released DreamerV3 checkpoint trained on DMC walker-walk, where imagined iKCE runs roughly two orders of magnitude above that of matched real-physics rollouts. Across a friction sweep that crosses the gait-collapse boundary, the model's iKCE stays statistically flat even as the trained policy's reward collapses through the same range, providing the kinematic-not-dynamic signature. The diagnostic distinguishes kinematic from dynamic imagination at horizons longer than the embodiment's gait period.

Finn Rasmus Schäfer, Korbinian Moller, Yuan Gao +3

Autonomous Vehicle Systems Lab Technical University of Munich, Garching b. München, Germany · Data Analytics and Machine Learning Group Technical University of Munich, Garching b. München, Germany

Long-Horizon Inference World Models Kinematics Imagination Gait Dynamics Diagnosis

Jul 6, 2026cs.SE

EvalLoop: A Methodology for Evaluation-Driven Iterative Improvement of Business AI Systems

Teams deploying large language models in business contexts need evaluation systems, yet most treat evaluation as static model selection: run benchmarks, rank models, deploy the winner. This framing misses evaluation's primary value for production systems--diagnosing why a system underperforms and guiding what to fix. We present EvalLoop, a methodology for evaluation-driven iterative improvement. EvalLoop organizes evaluation around three mechanisms: (1) dimensional metric grouping that decomposes quality into business-relevant dimensions enabling orthogonal failure diagnosis; (2) failure mode classification that categorizes why outputs fail within weak dimensions, bridging diagnosis to action; and (3) a structured iteration workflow where each evaluation run varies one system variable and compares dimensional profiles before and after. We validate EvalLoop through a case study on sales intelligence briefing generation (10 models, 3 providers, 18 metrics, 5 dimensions, 3 iterations). Dimensional diagnosis identified that 69% of hallucination failures were prompt-induced interpretation errors--invisible in aggregate scoring. A targeted prompt fix improved the best model from 82.6% to 94.6% overall, with improvement concentrated in diagnosed dimensions (Content Accuracy +16.8pp, Synthesis Power +26.4pp). An undirected configuration change in a prior iteration produced zero impact, illustrating the cost of iterating without diagnosis. We additionally demonstrate that dimensional profiling enables deployment-specific model selection, and that a one-time blind human gate on a finalist panel (4 models, 16 cases) confirms dimensional rankings while resolving multi-criteria deployment trade-offs--a 94% reduction in review burden compared to evaluating the full design. EvalLoop is packaged as reusable artifacts (playbook, agent specification, template repository) for adoption by other teams.

Kenneth Benavides, Josh Fleischer, Danti Chen

Robert Half

Loop Methodology Model Selection Diagnosis

Jul 6, 2026cs.CL

FormalRx: Rectify and eXamine Semantic Failures in Autoformalization

The veracious semantic alignment in autoformalization is significant for formal mathematical reasoning. However, existing evaluations provide only opaque binary verdicts or scalar scores, offering no interpretable insight into where or why translations fail. This opacity severely limits both human understanding and automated system improvement. To bridge this gap, we introduce FormalRx, a comprehensive diagnostic evaluation framework that transforms autoformalization assessment from black-box judgments into actionable feedback. At its core is SCI Error Taxonomy, a hierarchical classification scheme decomposing autoformalization errors into 28 distinct categories with strict priority ordering. Building on this taxonomy, FormalRx provides four critical diagnostic capabilities: alignment verdicts, error categorization, error localization, and correction. We instantiate the framework with a diagnostic model FormalRx-8B, trained on 56,287 NL-FL pairs with fine-grained diagnostic annotations, and release FormalRx-Test as the first fine-grained diagnostic benchmark. FormalRx-8B achieves F1-scores of 0.88 (verdict) and 0.71 (categorization), along with accuracies of 0.75 (localization) and 0.73 (correction), substantially outperforming both general-purpose LLMs and specialized baselines. By connecting evaluation with actionable insights, FormalRx enables systematic diagnosis and improvement of autoformalization systems.

Haocheng Wang, Baiyu Huang, Yingjia Wan +4

LARK Lab, HKUST(GZ) · ETH Zurich · UCLA +3

Autoformalization Formalization Diagnosis Hierarchical Semantic Alignment Auto Research Localization

Jul 5, 2026cs.AI

Measuring Harness-Induced Belief Divergence in Multi-Step LLM Agents

Software-agent benchmarks usually report whether an agent solves a task, but the agent reaches that outcome through a harness that controls what it sees, which actions it can take, which failures are repaired, which states are verified, and which evidence is logged. We show that this harness can change the agent's multi-step beliefs even when the task, environment, and base LLM are fixed. We introduce a belief-rollout diagnostic that elicits structured K-step trajectories over progress, risk, recoverability, constraints, failure mode, uncertainty, future success, repair cost, and next action under alternative harnesses. We define a cross-harness belief divergence and decompose it into an arrival term for immediate interface shifts and a growth term for horizon-dependent belief changes. On controlled coding tasks and public-benchmark stress tests, blocked actions, compressed repairs, selective verification, and cost-aware evidence pruning often preserve terminal success while changing the beliefs that drive later decisions. We further introduce BIWM, a no-training protocol that canonicalizes observations, logs censored branches, expands repair traces, records verification masks, executes risky branches in shadow, and aligns belief trajectories across harness views. The results suggest that harness design is an experimental variable in agent evaluation, not an implementation detail. Our code is available at https://github.com/Hik289/Harness-induce-bias.git.

Haiwen Yi, Xinyuan Song

University of Toronto · Emory University

Agent Harness Large Language Model Agents Diagnosis

Jul 5, 2026physics.plasm-ph

Benchmarking Sensor Robustness in Plasma Diagnostic Models: A Systematic Evaluation on TokaMark

Plasma diagnostic models for tokamak fusion devices are almost universally evaluated on clean, complete sensor data. In practice, fusion diagnostics fail regularly: acquisition systems start late, individual sensors die, and signal dropouts cluster precisely when a plasma disruption is approaching. We present the first systematic robustness benchmark for plasma diagnostic ML using the TokaMark dataset of 11,573 MAST shots, evaluating XGBoost, LSTM, Transformer, and the TokaMark CNN baseline across six physically-grounded failure scenarios and three imputation strategies. We introduce the Robustness Score (RS) for standardized cross-architecture comparison. Our central finding is that disruption-proximate sensor failure (corruption injected in the final window timesteps) collapses sequence model performance (LSTM +212% NRMSE) while a statistical feature model remains comparatively stable (XGBoost +37%). Forward-fill imputation eliminates nearly all degradation from random dropout for sequence models (LSTM +57% to ~0%), but offers little help when the end of the window is corrupted. Shot-level alarm evaluation using ground-truth disruption timestamps reveals that LSTM alarm detection collapses to TPR=0.00 under proximate sensor failure, while mean-fill imputation recovers it to TPR=1.00, a reversal of the pattern observed in NRMSE. Plasma current emerges as the single most critical diagnostic across all architectures (+73% to +140% upon removal). Code, data, and trained checkpoints are available at https://github.com/Neerav-Gupta/tokamark-robustness.

Neerav Gupta

Independent Researcher

Robustness Verification Diagnosis Convolutional Neural Networks

Jul 5, 2026cs.IR

Submitted and Diagnostic Analysis of Full-Text Temporal Retrieval for LongEval-Sci

LongEval-Sci evaluates scientific retrieval under collection change, where a system should be effective on the current corpus and remain usable as documents accumulate over time. This paper reports both official Task 1 results and development diagnostics for LongEval-Sci 2026. We compare the official PyTerrier BM25 and Qwen3 dense baselines with full-text BM25, additive and router variants, temporal full-text retrieval, temporal+citation retrieval, RM3 query expansion, cross-encoder reranking, and reciprocal rank fusion (RRF). In the official DCTR evaluation, the temporalized full-text runs are our strongest submissions: FT BM25+temporal and FT BM25+temporal+citation obtain the best ARP on all three snapshots (0.285, 0.267, and 0.180 nDCG@10) and reduce snapshot-3 relative change from 0.481 for the BM25 pivot to 0.368. Citation features match the temporal-only variant but do not provide a measurable additional gain in the official summary. Our internal snapshot-1 diagnostics show a complementary pattern: full-text BM25 is the strongest single development retriever (DCTR nDCG@10 = 0.3302, MAP = 0.2853), RRF gives the best deep recall (Recall@1000 = 0.9667), and some uncalibrated overlays can sharply degrade top-rank quality. We therefore conclude that full-text retrieval is the strongest foundation, temporal integration can improve official longitudinal effectiveness when applied to that foundation, and citation evidence still requires cleaner ablation and calibration. Beyond ranking, we also report a qualitative weekly IR-system update-monitoring analysis based on ingestion velocity and stale-coverage drift.

Yingdong Yang, Haijian Wu

Jena, Germany

Retrievers Citations Precision Recall Scientific Discovery Diagnosis

Jul 4, 2026eess.IV

Cross-Modal Fusion of OCT and OCT angiography enface for Improved Diagnostics of Diabetic Retinopathy

Diabetic retinopathy (DR) is a leading cause of vision impairment worldwide, highlighting the need for accurate and accessible screening tools. Optical Coherence Tomography (OCT) provides high-resolution structural information of the retina, whereas OCT angiography (OCTA) offers complementary vascular information that is highly relevant for DR diagnosis. In this study, we propose a cross-modal fusion of OCT B-scans with single-channel en face OCTA using a bidirectional cross-modal attention network for automated DR classification. Two independent datasets, OCT500 and UIC, comprising 730 subjects in total, were utilized to evaluate performance under within-dataset, combined-dataset, and cross-dataset generalization settings. A ConvNeXt V2 model trained solely on OCT images served as the unimodal baseline. In addition to ground-truth (GT) OCTA, we explored the use of translated (TR) OCTA generated from OCT scans, eliminating the requirement for dedicated OCTA hardware. Experimental results demonstrate that cross-modal fusion consistently outperforms unimodal OCT classification across all evaluation scenarios. Fusion with GT OCTA improved classification accuracy and discriminative performance, while TR OCTA achieved comparable or superior results in most settings. Furthermore, TR OCTA improved sensitivity and cross-dataset generalization, indicating enhanced robustness to domain shifts. These findings demonstrate that attention-based OCT-OCTA en face fusion provides clinically meaningful improvements for DR detection and suggest that computationally generated OCTA can serve as a practical, low-cost alternative to hardware-acquired OCTA, enabling broader deployment of high-performance retinal screening systems in resource-limited clinical environments.

Rashadul Hasan Badhon, Atalie Carina Thompson, Jennifer I. Lim +2

Optical Coherence Tomography Glaucoma Detection Coronary Angiography Cross-Modal Fusion Cross-Modal Attention Diagnosis

Jul 3, 2026eess.AS

An Intervention-Based Framework for Shortcut Diagnosis in Spoofing Countermeasures

While deepfake audio detection systems achieve high performance in controlled benchmarks, their reliability often diminishes in the wild. Prior work shows that dataset-specific artifacts contribute to this gap. Yet, systematic tools to identify which acoustic properties a model exploits as shortcuts remain limited. We propose an intervention-based diagnostic framework, grounded in a directed graphical model, that formally distinguishes confound-driven shortcut dependencies from legitimate domain shift. We operationalise this through controlled acoustic perturbations targeting non-speech structure, spectral content, and signal energy, complemented by corpus-level distributional analysis. Evaluating XLS-R-300M with RawGAT-ST across ASVspoof challenges datasets, we quantify model sensitivity to specific intervention types. Results reveal that non-speech interventions produce the largest performance shifts, confirming non-speech intervals as a dominant shortcut.

Santiago Rubio, Pilar Bello, Dayana Ribas +3

ViVoLab, Arag´on Institute for Engineering Research (I3A), University of Zaragoza, Spain · BTS, Business Telecommunications Services, Spain

Deepfake Detection Acoustic Diagnosis Latent Confounders

Jul 3, 2026cs.AI

Reinforcement Learning for Evidence-Seeking Diagnostic Reasoning with Large Language Models

Recent reasoning-centric Large Language Models (LLMs) have made significant strides, yet they predominantly operate on a passive-inference pattern that assumes complete information. In contrast, real-world clinical intelligence is inherently an iterative investigative process requiring strategic evidence acquisition. To bridge this gap, we formalize medical diagnosis as an Iterative Evidence-Seeking Task. We leverage Reinforcement Learning with Verifiable Rewards (RLVR) to elicit intrinsic reasoning within a closed-loop environment, guided by a novel suite of rewards that enforce diagnostic precision and examination consistency. To facilitate this, we introduce the Retrieval-Augmented Generation-based Examination Simulator (RAGES), a high-fidelity clinical oracle that provides realistic, knowledge-grounded follow-up evidence. Empirical results across diverse datasets demonstrate that our framework enables LLMs to transition from passive responders to autonomous assistants. Notably, our model demonstrates comparable performance to larger and reasoning-enhanced baselines, while RAGES proves superior to vanilla LLMs in generating biologically plausible clinical feedback.

Shengyi Hua, Kangzhe Hu, Conghui He +2

Qing Yuan Research Institute, Shanghai Jiao Tong University · Shanghai AI Laboratoty · Shanghai Innovation Institute

LLM Reasoning Strategies Diagnosis

Jul 1, 2026cs.LG

Aionoscope: Debugging Latent-State Accessibility in Time-Series Representations

Time-series models are often evaluated by what they can forecast or classify, but those scores do not show whether their representations preserve the process state a user may want to inspect: event timing, phase, amplitude, frequency, or regime variables. We introduce Aionoscope, a generator-based diagnostic tool for debugging latent-state accessibility in frozen time-series representations. Aionoscope separates process generation from observation rendering, producing seeded synthetic streams with exact categorical and dense labels across mixture complexity and nuisance variation. We instantiate Aionoscope as Primitive Process Mixtures and evaluate 37 model-plus-adapter systems with a common pooled linear-probe protocol. The main result is a mismatch between coarse and fine-grained accessibility. Most systems make component presence easy to recover, but expose dense process state much less reliably: the highest observed dense-probe row reaches 0.689 mean masked

R^2

, while a dense-feature oracle reaches 0.999. This is the failure mode Aionoscope is designed to surface: a representation can look informative at the level of "what kind of signal is present" while hiding the timing, phase, amplitude, frequency, or regime variables needed for debugging.

Alexander Chemeris, Ming Jin, Randall Balestriero

Langotime South Africa · Griffith University Australia · Brown University United States

Latent States Time Series Diagnosis Dense

Jul 1, 2026cs.CL

What Survives Into Context: A Diagnostic for Budget-Constrained Multi-Hop RAG and When Submodular Evidence Packing Improves It

Retrieval-augmented generation (RAG) under a fixed reader-context budget forces a selection problem: of the evidence retrieved, only a fraction can be shown to the reader. We argue that document recall -- the standard retrieval metric -- is the wrong quantity to optimize in this regime, and we make two contributions. First, as a general contribution, we introduce answer-in-context, a diagnostic that measures whether a gold answer survives as a contiguous span in the packed reader context (not the retrieved set). It predicts answer F1 better than recall (r=0.39-0.55 vs. about 0.31), separates answer quality roughly five-fold (0.60 vs. 0.12 on HotpotQA), and carries information beyond retrieval: it adds Delta R squared=0.17 over recall and shows a 4.6x EM gap even among questions where all gold was retrieved. We also confirm it interventionally: on 2WikiMultiHopQA a packing change that raises coverage but not answer-in-context yields no accuracy gain. Second, as a conditional contribution, we cast reader-context construction as budgeted monotone submodular maximization and build a packer that jointly optimizes relevance, query coverage, representativeness, and diversity. On HotpotQA with a 160-token budget and a 3B reader it beats a strong focused heuristic, MMR, and naive packing -- by up to +5.1 F1 at equal-or-lower token cost, across three seeds. Crucially, we map the scope of this win honestly: it requires the conjunction of (i) multi-hop complementary structure, (ii) retrieval that surfaces the evidence, (iii) a binding but not extreme budget, and (iv) a reader weak enough that evidence density, not reading capacity, is the bottleneck. A quantization-controlled reader-scale ladder (3B to 7B to 14B) shows the edge over the heuristic is absorbed by 7B and significantly reverses by 14B, while the diagnostic explains every boundary with a single variable.

Ananto Nayan Bala

Ahsanullah University of Science and Technology

Answer Factual Recall Token Budget Allocation Submodular Functions Diagnosis

Jun 29, 2026cs.CV

GRAPE: Graph-Augmented Prototype Explanations for Interactive Medical Image Diagnosis

Prototype-based medical image classifiers present three clinical limitations: they treat findings as independent, silently amplify unsafe physician feedback, and require full retraining whenever a new finding is needed. We present GRAPE (Graph-Augmented Prototype Explanations), a unified architecture that addresses all three challenges. First, a Graph Attention Task Head models anatomical concept co-occurrence, boosting macro-F1 by +13.8,pp over the prototype baseline on TBX11K. Second, a Concept-Mismatch Safety Check - the first such mechanism in prototype-based medical classifiers - warns when the model's dominant finding inside a doctor-drawn region conflicts with the claimed label, catching 85% of erroneous annotations versus 51% for MC-Dropout with no extra inference cost. Third, Open-Vocabulary Prototype Anchoring aligns visual prototypes to clinical text, allowing a new finding to be added from a single labeled image without modifying any other component. On NIH ChestX-ray14, one Effusion example recovers full-supervision localization accuracy; on TBX11K, prototype maps achieve 2.6x better lesion localization than end-to-end baselines. All three capabilities add only +1~ms latency at interactive batch size. The project page is https://github.com/KurbanIntelligenceLab/GRAPE.

Rasul Khanbayov, Erchin Serpedin, Hasan Kurban

1Hamad Bin Khalifa University · 2Texas A&M University

Lesion Diagnosis Explainable AI Methods Token Co-Occurrence Graphs

Jun 29, 2026cs.LG

From Failure Taxonomy to Intervention: A Diagnostic Methodology for Industry-Scale AVLM in Video and Live-Streaming Platform Moderation

Industry-scale video and live-streaming moderation imposes requirements that are difficult to satisfy with generic pretrained public models or external APIs, including adaptation to platform-specific data distributions, policy-specific objectives, and product-level safety constraints. As a result, platforms must undertake internal model development, naturally turning to shared public research for guidance. However, existing multimodal foundation-model studies primarily report architectures, training recipes, data scaling strategies, and benchmark results, but provide less systematic guidance on how failures should be localized and translated into targeted model-development interventions. Interventions are essential because deployment failures are rarely self-explanatory. Similar failures can originate from different causes. Without targeted interventions, improvement reduces to heuristic trial-and-error, where benchmark improvements are weakly attributable, and failures are difficult to trace to their underlying causes. To address this gap, we present a diagnostic methodology for industry-scale Audio-Visual-Language Models AVLM development. The methodology maps model failures into a taxonomy of observable failure signatures and links each class of failure to an intervention space. We instantiate this methodology across the development and alignment lifecycle of an AVLM foundation model for a large-scale video and live-streaming platform. The resulting system supports over 100 regions and is designed for noisy, ambiguous, and highly diverse content drawn from global platform traffic.

Shuchang Ye, Jinqiang Yu, Zhujun Xiao +6

1TikTok

Content Moderation Streaming Video Violation Methodology Large Audio Language Models Diagnosis

Jun 29, 2026cs.IR

Diagnosing and Mitigating Retrieval Bottlenecks in LLM-Based Cold-Start Recommendation

Large language models (LLMs) are increasingly used as rerankers in recommender systems, with the expectation that semantic understanding will help in cold-start and long-tail regimes. We test this assumption with a five-domain benchmark that explicitly separates reranking quality from retrieval coverage. In a positive-controlled regime where the gold item is guaranteed present, calibrated LLM rerankers fail to consistently outperform strong collaborative and content baselines under natural traffic, and within-family scaling from Qwen3-8B to Qwen3-32B narrows but does not close the gap on most domains. In a retrieval-realistic regime where the gold item is not injected, the bottleneck is more severe: standard single retrievers place the gold item in a 200-item pool only 4.6-22.9% of the time, largely because 32-91% of cold-start targets are brand-new items with no training interactions. We introduce LHF, a validation-trained learned hybrid fusion layer over a multi-retriever union pool, as a retrieval-side realizability baseline. LHF is the only combiner we test that beats every single retriever on all five domains and recovers 17-61% of oracle coverage headroom on content-rich domains, but only 5-7% on collaboratively strong domains. End-to-end experiments reveal the remaining mismatch: learned non-LLM ranking exploits the LHF pool, while prompt-level LLM reranking often degrades it. LLMs exhibit pockets of semantic cold-start advantage, especially in text-rich domains when the item is already present, but this advantage is largely unreachable in current retrieve-then-rerank pipelines. We release the benchmark protocol, splits, prompts, evaluation tooling, and archived reproducibility artifacts: data at https://doi.org/10.5281/zenodo.20991039 and code at https://doi.org/10.5281/zenodo.20993306.

Zhe Dong, Fang Qin, Manish Shah +1

University of Maine at Presque Isle · Stanford University · 2Stanford University +2

Reranking Cold-Start Large-Scale Benchmark Bottlenecks Diagnosis

Jun 29, 2026cs.CL

Clinical Reasoning Graphs: Structured Evaluation of LLM Diagnostic Reasoning Reveals Competence Without Consistency

Modern large language models (LLMs) reach 60-70% diagnostic accuracy on complex clinical case benchmarks, but accuracy alone cannot distinguish stable clinically-grounded reasoning from pattern matching. We introduce clinical reasoning graphs, structured graph representations extracted from free-text LLM diagnostic traces using a domain-grounded ontology with 5 node types and 7 edge types. We apply this pipeline to 750 traces from five LLMs across 50 New England Journal of Medicine Clinicopathological Conference cases and three prompt conditions, and test whether diagnostic traces show stable structured reasoning patterns, or diagnostic schemas, for clinically similar cases. We operationalize this as higher graph similarity among clinically similar cases than among clinically dissimilar ones. Across 15 model-condition comparisons, within-cluster and between-cluster composite similarity are nearly equal, and no comparison survives multiple-testing correction; a component-level analysis finds any residual content signal far below schema scale. Graph similarity is also nearly identical for pairs of models that are both correct (0.488) and both incorrect (0.484), suggesting that graph structure captures a dimension not reflected in diagnostic accuracy. Structured reflection prompting increases explicit discriminating-feature analysis within traces (+33%) but does not increase cross-case consistency. These results show diagnostic competence without schema-scale reasoning consistency, and indicate that final-answer accuracy should be complemented by process-level evaluation. We release the ontology, extraction pipeline, validation protocol, and the extracted reasoning graphs and similarity artifacts as resources for structured evaluation of LLM clinical reasoning.

Nisarg A. Patel

University of California, San Francisco · Department of Oral and Maxillofacial Surgery, University of California, San Francisco, CA, USA · Department of Medicine, Division of Clinical Informatics and Digital Transformation, University of California, San Francisco, CA, USA

Reasoning Graphs Diagnosis Tool-Grounded Reasoning Ontology

Jun 26, 2026cs.LG

What Was That Again? Certified Robustness for Automatic Speech Recognition

Automatic Speech Recognition systems are notoriously both sensitive to adversarial and benign perturbations. While this has been repeatedly demonstrated using reference datasets, detecting such behaviors in deployed systems is incredibly challenging, due to the absence of oracle knowledge of the true transcription. We demonstrate that employing a certification-inspired mechanism can significantly decrease WER, increase recall, and decrease the Spearman correlation between confidence and WER. We achieve this through a dual-gate diagnostic pipeline: a Two-Sided Atomic Audit that accumulates statistical wealth to certify both token existence and adversarial exclusion, and a Rank-Based Tournament that selects the winning sequence. Our evaluations across four diverse architectures demonstrate up to a 55% relative reduction in Word Error Rate, while also providing granular word- and sentence-level certifications to enhance acoustic security.

Andrew C. Cullen, Neil G. Marchant, Jiani Xie +2

University of Melbourne · DST Group, Adelaide

Automatic Speech Recognition Acoustic Diagnosis

Jun 25, 2026cs.CV

MedDiffuseMix: Preserving Diagnostic Evidence with Saliency-Aware Diffusion Medical Image Data Augmentation

Limited data availability, class imbalance, and domain variability remain major barriers to reliable medical image classification. Conventional augmentation can improve training diversity but may distort diagnostically informative structures, whereas unconstrained generative augmentation may introduce label-inconsistent content. This paper proposes MedDiffuseMix, a saliency-guided diffusion mixing framework for controlled medical image augmentation. The method uses classifier-derived saliency maps to separate high-saliency diagnostic regions from low-saliency background areas and applies diffusion-guided mixing mainly to regions with lower diagnostic importance. Adaptive mixing, Gaussian boundary blending, and a saliency-preservation constraint reduce semantic distortion and reject or attenuate samples that shift model attention away from clinically relevant evidence. The framework is evaluated on four public benchmarks: the Radiological Society of North America pneumonia chest radiography dataset, Musculoskeletal Radiographs, PatchCamelyon, and the Breast Cancer Histopathological Image Classification dataset. Experiments with convolutional and transformer-based classifiers show that MedDiffuseMix improves accuracy, F1-score, and area under the receiver operating characteristic curve compared with standard augmentation, Mixup, GenMix, SaliencyMix, and diffusion-based augmentation baselines. Ablation studies confirm the importance of saliency guidance, adaptive region mixing, and smooth boundary blending. Visual attribution analysis further indicates that MedDiffuseMix better preserves diagnostically salient regions. These results suggest that saliency-guided diffusion mixing is an effective augmentation strategy for limited-data medical image classification.

Teerath Kumar, Raja Vavekanand, Muhammad Turab

School of Computing, Atlantic Technological University, Letterkenny, Ireland. · Department of Information Technology, Benazir Bhutto Shaheed University Lyari, Karachi, 75660, Pakistan. · School of Computing, Dublin City University, Dublin, Ireland.

Medical Image Classification Data Augmentation Diagnosis Query Image

Jun 23, 2026q-bio.GN

DeepBD: A Grounded Agentic Workflow for Variant Prioritization and Diagnosis of Genetic Birth Defects

Birth defects are a major cause of fetal loss, neonatal morbidity and long-term disability. In the subset with suspected genetic etiologies, exome and genome sequencing have moved many cases from variant detection to post-sequencing interpretation: clinicians must rank patient-specific candidate variants under incomplete fetal or infant phenotypes and heterogeneous evidence from population genetics, variant-effect prediction, gene-disease validity, phenotype ontologies, cellular and pathway context, protein structure and clinical literature. We present DeepBD, a grounded agentic workflow for variant prioritization and diagnostic interpretation of genetic birth defects. DeepBD organizes the workflow into LLM-assisted case structuring, a pretrained evidence engine, specialist evidence modules and a grounded diagnostic review layer. The evidence engine learns patient-specific variant scores from structured rule evidence, sequence and variant-effect representations and phenotype-conditioned biological context, whereas specialist modules and the agentic layer provide tool-based refinement, candidate-pool review and diagnosis-oriented synthesis from ranked candidates. Developed using an in-house fetal and infant cohort comprising 18,622 cases, DeepBD achieved Recall@1/3/5/10 of 0.658/0.882/0.912/0.929 on an internal held-out solved-case benchmark, outperforming standalone Exomiser, DeepRare and prompted LLM reranking baselines evaluated on Exomiser-derived top-20 candidate variants. Ablation and overlap analyses show that rule evidence, mechanistic context, and specialist refinement provide complementary signals. These findings support a grounded agentic workflow that separates evidence integration, tool-based refinement, and LLM-assisted diagnostic review for retrospective variant prioritization in genetic birth defects.

Shiyu Li, Ziqi Yan, Zhihao Wu +7

College of Computer Science and Technology, Zhejiang University, Hangzhou, China

Diagnosis Prioritization Agentic Workflows

Jun 23, 2026cs.AI

Diagnosing and Mitigating Compounding Failures in Agentic Persuasion via Taxonomic Strategy Retrieval

Foundation-model agents in multi-step, open-ended environments frequently suffer from compounding errors, where early mistakes contaminate long-horizon trajectories. While Multi-Agent Debate (MAD) succeeds in deterministic domains, agents in subjective tasks like persuasion experience severe problem drift and sycophantic conformity. We identify semantic leakage in standard Retrieval-Augmented Generation (RAG) as a reproducible trigger for these failures, as standard RAG prioritizes vocabulary overlap over logical necessity. To eliminate this leakage, we introduce Taxonomic Strategy RAG (TS-RAG), a systems intervention that routes strategies through a discrete categorical bottleneck to decouple argumentative structure from topical content. Zero-shot, cross-domain evaluations demonstrate that TS-RAG significantly improves the transfer of abstract logic where standard semantic retrieval collapses. Crucially, TS-RAG acts as a "capability bridge" in asymmetric deployments, empowering lightweight persuaders to consistently defeat parametrically superior opponents (improving win rates from 70.5 to 78.5) and accelerating argumentative efficiency. Finally, we introduce trace-level diagnostics via a turn-by-turn Debate State Representation (DSR), demonstrating the necessity of strict constraints to prevent evaluation collapse via default agentic sycophancy.

Sana Ayromlou, Purvi Sehgal, Pradyumna Narayana

Google

Multi-Agent Debate Persuasion Agentic Retrieval-Augmented Generation Systems Argumentation Frameworks Taxonomy Diagnosis+1

Jun 23, 2026eess.AS

A Fusion-Aware Two-Stage Framework for Mispronunciation Detection and Diagnosis in Low-Resource Modern Standard Arabic

Accurate phoneme recognition is pivotal for mispronunciation detection and diagnosis (MDD) in modern standard Arabic (MSA), yet remains constrained by data scarcity and the synthetic-real domain gap. This work proposes a two-stage end-to-end framework. It integrates a pre-trained encoder with causal dilated temporal convolutional networks to preserve fine-grained phonetic variations. A hierarchical two-stage strategy first learns general mappings from native/synthetic corpora, then adapts to scarce real learner data to mitigate domain shift without over-correction. Prediction stability is further enhanced via multi-checkpoint ensemble inference with N-gram rescoring. Evaluated on the QuranMB.v2 test set, our system achieves an F1-score of

0.7201

, a

63.1

% relative improvement over baseline (

0.4414

). This performance ranks at the top of the IqraEval.2 Challenge, establishing a new state-of-the-art for low-resource MSA in MDD.

Jing Yang, Shuqing Zhang, Yongyi Deng +5

School of Electronic Information, Wuhan University, Wuhan Hubei, 430072, China · School of Computing and Information Systems, University of Melbourne, Melbourne, Australia · Northwestern Polytechnical University +1

Arabic Natural Language Processing Arabic Synthetic-To-Real Domain Gap Unigram Tokenizer Diagnosis Temporal Convolutional Networks

Jun 22, 2026eess.IV

E-MRL: Cross-view Aligned Evidence-driven Multimodal Reinforcement Learning for Reliable 3D Tumor Analysis

While Vision-Language Models (VLMs) show great promise in volumetric medical report generation, they frequently suffer from visual hallucinations and a lack of grounding in 3D CT data. Current Supervised Fine-Tuning (SFT) and Reinforcement Learning (RL) strategies typically optimize text fidelity alone, essentially rewarding correct diagnoses derived from language priors rather than genuine visual perception. To address this, we propose cross-view aligned Evidence-driven Multimodal Reinforcement Learning (Evidence-MRL, noted as E-MRL), a reliable RL reasoning framework that formulates the generation process as a Markov Decision Process of "diagnosis-localization-verification". Unlike standard approaches, our model is explicitly trained to identify a "key evidence slice" alongside the global diagnostic report, grounding its findings in verifiable visual evidence. Crucially, we introduce a novel cross-view consistency reward, which validates the semantic alignment between the golden-standard report and a local visual re-query of the selected key slice, providing additional rewards for correctly-localized reasoning. Experiments on large-scale 3D CT tumor datasets demonstrate that E-MRL significantly reduces hallucinations and improves diagnostic accuracy compared to SFT and RL baselines, offering a clinically interpretable solution for visually-grounded and tumor analysis.

Sijing Li, Zhongwei Qiu, Zhuoya Wang +6

Zhejiang University · DAMO Academy, Alibaba Group · Hupan Lab +3

Medical Vision-Language Models Multimodal Clinical Data Longitudinal Imaging Cross-View Diagnosis Visual Hallucinations

Jun 20, 2026eess.AS

Using Phonological-Level Wav2Vec2 for Mandarin Automatic Mispronunciation Detection and Diagnosis

Automatic mispronunciation detection and diagnosis (MDD) plays a crucial role in L2 Mandarin pronunciation learning. While end-to-end (E2E) based MDD methods have substantially improved phoneme-level detection accuracy, diagnostic feedback remains limited, as segmental and tonal errors are not explicitly separated. In this paper, we propose a phonological feature-based MDD framework that models both segmental and tonal attributes within a unified Wav2Vec2 CTC architecture. Experimental results show that the proposed method reduces the False Acceptance Rate (FAR) by 10.1% and the Diagnostic Error Rate (DER) by 23.6% compared with the phoneme-only baseline system. By decomposing phonemes into low-level phonological components, the proposed approach enables more detailed and interpretable diagnostic feedback for L2 learners.

Jinghao Chen, Mostafa Shahin, Beena Ahmed

School of Electrical Engineering and Telecommunications, UNSW, Australia

Grapheme-To-Phoneme Wav2Vec Mandarin Diagnosis

Jun 19, 2026cs.LG

Objective-Behavior Alignment: Diagnostics for MORL Policy Selection

Real-world decision-making often requires optimizing multiple competing objectives simultaneously. In reinforcement learning (RL), this is typically addressed by combining reward signals into a single scalar objective via a scalarization function, which can be fragile: small changes in the weights can induce drastically different policies. Multi-objective reinforcement learning (MORL) instead produces sets of policies that explicitly represent trade-offs between objectives. However, these policies are typically presented to the decision maker only through their value vectors, which can obscure substantial behavioral variation: policies that induce distinct trajectories may appear indistinguishable when evaluated solely by expected returns. We propose an exploratory diagnostic workflow that automatically highlights behavioral variation along the Pareto front that objective values alone do not reveal, providing both quantitative and visual tools to support policy inspection. We validate our approach on simple grid examples and scale it to continuous control benchmarks, demonstrating that it remains effective as problem complexity increases.

Antonio Mone, Zuzanna Osika, Florian Felten +4

Delft University of Technology, the Netherlands · ETH Zurich, Switzerland & herve.review, Belgium · ETH Zurich, Switzerland

Multi-Objective Reinforcement Learning Behavioral Divergence Diagnosis Inspection

Jun 18, 2026cs.SE

A Unified Framework for Runtime Verification and Model-Based Diagnosis in LOLA

We present an integrated framework that unifies runtime verification and model-based diagnosis within the stream specification language LOLA. By encoding system descriptions, component health states, and observations into a single stream-based formalism, the approach enables continuous, online fault localization directly alongside fault detection, without requiring separate toolchains. The framework supports both time-invariant and transient faults, and naturally accommodates nondeterministic observations.

Raik Hipler, Martin Leucker, Patrick Rodler

University of Luebeck, Luebeck, Germany · University of Klagenfurt, Klagenfurt, Austria

Fault Diagnosis Runtime Enforcement Diagnostic Framework Diagnosis Unified Framework

Jun 17, 2026cs.SE

JustDiag!: A Diagnostic Justification Engine for Accountable Root Cause Analysis

Large language models can produce fluent root cause analyses, but fluent final answers alone are insufficient evidence for accountability in high-stakes operations. In real incident response, engineers need to know what evidence supported a diagnosis, which alternatives were considered, where contradictions remained, and whether the system resolved the case or preserved uncertainty. We address this gap with JustDiag, a diagnostic justification engine for RCA that maintains an explicit process state over evidence, findings, competing hypotheses, conflicts, and next checks. We evaluated the system on 66 real-world incidents using a two-layer protocol that separately scores final-answer quality and process quality. Relative to a matched control without diagnostic justification, JustDiag achieved stronger outcome and process scores, while accepting slightly lower terminal completion due to more calibrated non-closure. These results suggest that accountable RCA requires explicit diagnostic justification artifacts and process-aware evaluation, not only fluent final answers.

Tingzhu Bi, Xinrui Jiang, Xun Zhang +5

Peking University · University of Edinburgh · Beijing University of Posts and Telecommunications

Root Cause Analysis Diagnosis Incident Response

Jun 17, 2026cs.CV

Benchmarking Large Vision-Language Models on Fine-Grained Image Tasks: From Evaluation to Diagnosis

Recent advancements in Large Vision-Language Models (LVLMs) have demonstrated remarkable multimodal perception and reasoning capabilities. While numerous benchmarks have evaluated LVLMs from holistic or task-specific perspectives, their capabilities on fine-grained image tasks-fundamental to computer vision-remain insufficiently understood. To address this gap, we introduce FG-BMK, a comprehensive fine-grained evaluation benchmark containing 1.01 million questions and 0.28 million images, covering diverse scenarios from common object-centric domains to specialized domains. FG-BMK jointly evaluates dialogue-level fine-grained semantic recognition and feature-level visual discriminability through human-oriented and machine-oriented paradigms, enabling diagnostic analysis of whether LVLM failures arise from insufficient visual representations, weak visual-to-semantic grounding, or limited fine-grained knowledge. Through extensive experiments on a diverse set of representative LVLMs/VLMs, we find that current LVLMs remain inadequate fine-grained recognizers, with failures arising from intertwined bottlenecks in visual representations, semantic grounding, modality alignment, and category-level knowledge. We further analyze training design factors for improving fine-grained capabilities and examine how visual and linguistic perturbations affect LVLM predictions. These findings provide diagnostic insights into the limitations of current LVLMs and offer guidance for future data construction and model design in developing more reliable LVLMs for fine-grained visual tasks. Our code is open-source and available at https://fg-bmk.github.io/.

Hong-Tao Yu, Chen-Wei Xie, Yuxin Peng +2

School of Computer Science and Engineering, Southeast University, China · Alibaba Group · Wangxuan Institute of Computer Technology, National Key Laboratory for Multimedia Information Processing, Peking University, China +2

Fine-Grained Perception Multimodal Benchmarks Diagnostic Benchmark Weak Visual Grounding Diagnosis

Jun 17, 2026cs.LG

Zero-Shot Active Feature Acquisition via LLM-Elicitation

Active feature acquisition (AFA) sequentially selects which features to observe to reach a classification or ranking decision. Its central limitation is reliance on large amount of labeled data to fit probabilistic models guiding acquisition. Large language models (LLMs) supply unsupervised domain knowledge, but are poor sequential planners. Asking one to both know and decide conflates capabilities best kept separate. Here, we develop a framework for zero-shot AFA through disciplined elicitation: asking the LLM only for what it can be trusted to return, the unary deviations and pairwise co-variations that are the sufficient statistics of a Markov random field (MRF). We apply our framework to two settings: binary classification and top-

k

identification. In practice, the LLM reliably returns only discriminative statistics, what distinguishes the classes rather than each class in isolation, which precludes classical AFA. We apply a maximum-entropy closure that resolves this gauge ambiguity. We evaluate on a cohort of Inflammatory Bowel Disease (IBD) patients, an active clinical setting where diagnostic ambiguity and patient heterogeneity obstruct stable treatment strategies. Our framework outperforms the LLM both on real labels and on its own extracted beliefs. Where it matters most, on the hardest patients, our top-

k

acquisition policy markedly outperforms all existing methods.

Binyamin Perets, Natalie Mendelson, Shiran Vainberg +3

Faculty of Medicine, Technion. · NVIDIA

Pool-Based Active Learning Feature Engineering Acquisition Diagnosis Elicitation

Jun 16, 2026cs.CV

Beyond Visual Cues: CoT-Enhanced Reasoning for Semi-supervised Medical Image Segmentation

Semi-supervised medical image segmentation has emerged as a dominant research problem in medical image analysis, mitigating annotation scarcity by leveraging consistency regularization on unlabeled data. However, existing approaches operate predominantly via visual pattern matching, relying heavily on pixel-level similarities. This visual-centric dependency often falters in clinical scenarios characterized by the visual-semantic mismatch, where visually similar lesions warrant distinct diagnostic conclusions, thus failing to capture the underlying diagnostic logic used by experts. To address this, we move beyond visual cues and propose CERS (CoT-Enhanced Reasoning Segmentation), a framework that integrates Chain-of-Thought (CoT) reasoning to distinguish pathologically distinct cases. Specifically, we construct a knowledge pool enriched with linguistic reasoning descriptions generated by large language models (LLMs). A semantic-aware reference selection strategy is introduced to identify historical evidence, filtering candidates first by morphology, and then refining them via CoT consistency to eliminate hard negatives. Furthermore, a multi-scale coordinate attention module (MCAM) is designed to effectively fuse this reasoning-derived context into the decoding process. Extensive experiments demonstrate the superiority of CERS against state-of-the-art approaches, particularly in resolving boundary ambiguities and semantic inconsistencies. The code is available at https://github.com/cymasuna/CERS.

Yuming Chen, Yuxin Xie, Tao Zhou +1

School of Computer Science and Engineering, Southeast University, Nanjing, China · Key Laboratory of New Generation Artiﬁcial Intelligence Technology and Its Interdisciplinary Applications, Ministry of Education, Nanjing, China · Nanjing University of Science and Technology, Nanjing, China

Semi-Supervised Medical Image Segmentation Diagnosis Visual Cues

Jun 16, 2026cs.AI

DiagFlowBench: Evaluating How Language Models Handle Off-Procedure Inputs in Grounded Diagnostic Dialogue

Language models increasingly serve as advisory systems in maintenance operations. To prevent hallucination, recent systems ground these models in procedural documentation to constrain them to approved steps. In practice, however, operator queries frequently stray from this path, requiring models to recognise out-of-scope inputs mid-conversation, a dynamic that current benchmarks rarely prioritise. We introduce DiagFlowBench, a dataset of 50 industrial diagnostic flowcharts from a consumer manufacturer converted into 1,676 multi-turn conversations that contrast compliant with out-of-scope utterances. Evaluating a panel of ten commercial and open-weight models reveals high variability in abstention rates, with models commonly selecting a real but contextually inadequate step rather than fabricating facts. The inherent plausibility and authority of this mapped but wrong advice exposes a challenging vulnerability for grounding systems.

Guillermo Gil de Avalle, Laura Maruster, Shaina Raza +1

University of Groningen, PO Box 72, 9700 AB Groningen, The Netherlands · Vector Institute for Artificial Intelligence, MaRS Centre, Toronto, ON, Canada

Diagnosis Large Language Models Fail Tool-Grounded Reasoning Advice

Jun 16, 2026cs.LG

TuneAhead: Predicting Fine-tuning Performance Before Full Training Begins

Fine-tuning large language models (LLMs) is compute-intensive and error-prone: model performance depends sensitively on data quality and hyperparameter choices, and naïve runs can even degrade model performance. This raises a practical question:can we predict fine-tuning performance before committing to a full training run? We present TUNEAHEAD, a lightweight framework for pre-hoc prediction of fine-tuning performance. TUNEAHEAD encodes each candidate run as a meta-feature vector that combines static dataset descriptors with dynamic probe features from a short standardized probe. A predictor maps these features to performance estimates, while SHAP-based attributions provide interpretable diagnostics that reveal which specific features drive the prediction. Across 1,300+ fine-tuning runs on Qwen2.5-7B-Instruct, TUNEAHEAD consistently outperforms strong baselines such as Early-Stop Extrapolation and ProxyLM. On a held-out test set of 370 runs, TUNEAHEAD achieves an RMSE of 1.47 percentage points and places 95.1% of predictions within +3/-3 percentage points of the true score. These accurate continuous predictions support practical go/no-go screening policies that can reduce unnecessary full fine-tuning while retaining most promising runs.

Yuxiang Luo, Haonan Long, Chen Wang +6

The Hong Kong University of Science and Technology (Guangzhou) · Huawei Technologies Ltd.

Model Fine-Tuning Tuning Diagnosis

Jun 16, 2026cs.CL

Scaling Enterprise Agent Routing: Degradation, Diagnosis, and Recovery

Production LLM assistants route user requests to growing libraries of specialized tools, but how does routing accuracy degrade as the catalog scales? We study single-step routing on a 110-agent, 584-tool catalog from a deployed enterprise productivity assistant, evaluating three frontier models from 10 to 110 agents. Routing F1 on under-specified requests drops 16--23 percentage points across models. An oracle analysis decomposes the degradation into a \emph{retrieval} gap (the model cannot surface the right tool) and a \emph{confusion} gap (even with perfect retrieval, the oracle ceiling drops 10pp). Embedding-based shortlisting recovers +10--11pp F1 at full scale across all three models and two providers. A production annotation study (1,435 human-labeled utterances, three annotators) confirms the recovery on real traffic at +10--17pp despite 10--15pp lower absolute performance.

Kellen Gillespie, Robyn Perry

Superhuman, Inc.

Large Language Model Routing Diagnosis Degradation

Jun 14, 2026cs.CV

NeRD: Neuro-Symbolic Rule Distillation for Efficient Ontology-Grounded Chain-of-Thought in Medical Image Diagnosis

Interpretability is essential for trustworthy medical image diagnosis. However, existing concept-driven interpretable methods have key limitations: Concept Bottleneck Models (CBMs) require scoring all predefined concepts at inference time and for manual intervention, imposing a substantial burden on clinicians, while rationale-based generative approaches often select concepts by class discriminability, which can drift from diagnostic ontologies. To address these issues, we propose Neuro-Symbolic Rule Distillation (NeRD), a framework that produces efficient, ontology-grounded reasoning chains that are sufficient yet non-redundant, without manually crafting diagnostic rules. Experiments on two skin datasets demonstrate strong diagnostic performance and interpretability, and blinded expert evaluation confirms the clinical plausibility of NeRD rationales. Our method further enables a first expert-in-the-loop study for Multimodal Chain-of-Thought-based diagnosis, achieving efficient and effective concept-level intervention.

Hongxi Yang, Yiwen Jiang, Siyuan Yan +8

Department of Data Science & AI, Faculty of Information Technology, Monash University, Melbourne, Australia · AIM for Health Lab, Faculty of Information Technology, Monash University, Melbourne, Australia · Faculty of Engineering, Monash University, Melbourne, Australia +2

Diagnosis Interpretability Medical Ontology Neuro-Symbolic Framework Chain-of-Thought Reasoning

Jun 14, 2026cs.SE

SDVDiag: Multimodal Causal Discovery for Online Diagnosis in Software-defined Vehicles

The transition toward software-defined vehicles concentrates an increasing share of vehicle functionality into distributed software services, where failures propagate through service dependencies and the surface symptom is often several causal hops away from the underlying defect. Existing approaches to causal root-cause analysis in such systems address this only partially: they typically reason over a single observability modality and operate in an offline, operator-driven mode that does not match the demands of continuous vehicle operation. This paper presents SDVDiag, a multimodal causal-discovery pipeline that fuses log-based and metric-based service representations into a shared embedding space before graph construction, coupled with an anomaly-driven trigger that converts the diagnostic platform from a manually operated batch tool into a continuously running online system. Evaluation on an Autonomous Valet Parking testbed shows that the multimodal pipeline produces sparser causal graphs than a metrics-only baseline (134 vs. 182 edges on average) and consistently outperforms it in edge-weighted reward against an expert knowledge graph at every stage of human-feedback refinement, showing a 2.4-fold improvement over the baseline after 60 feedback queries. An end-to-end fault-injection scenario further demonstrates that the integrated trigger correctly recovers a true root cause located two causal hops upstream of the observable symptom.

Matthias Weiß, Athreya Hosahalli Prakash, Falk Dettinger +2

Institute of Industrial Automation and Software Engineering (IAS) University of Stuttgart Pfaffenwaldring 47, 70550 Stuttgart, Germany

Root Cause Analysis Real-World Cloud Fault Injection Dataset Diagnosis Causal

Jun 13, 2026cs.CL

Prior over Evidence: Stereotype-Driven Diagnosis in LLM-Based L2 Pronunciation Feedback

Large language models are increasingly deployed for written pronunciation feedback in second-language (L2) English learning, under the assumption that their diagnoses are grounded in the supplied speech evidence rather than in priors from pretraining. This assumption is tested on 1,800 L2-Arctic utterances spanning six L1 backgrounds, three audio-capable LLMs, four pronunciation dimensions, and five evidence conditions ranging from a text-only baseline to numeric acoustic features and raw audio. Each (utterance x model x condition x dimension) cell is scored on three metrics: Rating Accuracy (RA) against gold labels, Evidence Coherence (EC) assessing internal consistency without ground truth, and Grounded Correctness (GC) evaluated against gold evidence. Results show three findings across models. First, rating accuracy and grounded reasoning decouple: 39.6% of judged cells contain internally coherent reasoning that supports a wrong rating, against only 15.8% where the reasoning supports a correct rating. Second, phoneme-level feedback converges to a fixed inventory of L2-English difficulty phones that recurs across all six L1 backgrounds and all evidence conditions. Third, acoustic evidence improves the rating only when the supplied feature directly probes the target dimension: textualised F0 range raises pitch-variation grounding from (0.18-0.19) to (0.45-0.62) across all three models, while stress and phoneme correctness, which require target-to-realisation alignment, remain ungrounded. The same audio waveform without textualised F0 values does not reproduce this improvement. These findings indicate that current general-purpose LLMs are more reliable as verbalisers of externally computed pronunciation evidence than as standalone diagnostic engines.

Rong Wang, Kun Sun

University of Tuebingen, Tuebingen, Germany · Tongji University, Shanghai, China

Pronunciation Assessment Linguistics Grapheme-To-Phoneme Diagnosis L2 Ground Truth

Jun 13, 2026cs.LG

Diagnosing Shape-Prior Shortcuts in Long-Range Single-Shot Fringe Projection Profilometry

Learning-based single-shot fringe projection profilometry (FPP) has been studied almost entirely at close range, and the networks used are evaluated only on aggregate error, leaving open whether they recover depth from fringe phase or from object-level shape cues that correlate with depth. This paper diagnoses that question mechanistically in the long-range regime (standoff beyond 1 m). Using FPP-ML-Bench, an open photorealistic synthetic benchmark (15,600 fringe images, 50 objects at 1.5--2.1 m), we first formalize why the single-shot fringe-to-depth mapping is more severely ill-posed at long range: it is non-injective without fringe-order information, and the depth error from an incorrect fringe order grows as

Z^2

in the working distance. Systematic ablations, extended with a multi-frame study, establish a best UNet baseline at 14.54 mm object mean absolute error (MAE), 18% of the 80 mm object depth range, with only a 1.9

\times

spread across four architectures, indicating a representational rather than a capacity-bound limit. A mechanistic interpretability study, the first applied to an FPP network, localizes the cause: linear probing shows edges are 2.82

\times

more decodable than depth, Grad-CAM shows attention favoring boundaries over fringes by 1.28

\times

, and an in-range flat-plane test collapses a featureless plane to background depth despite valid fringes. The baseline solves the task via object-boundary shape priors rather than fringe-phase decoding. Because the shortcut is a hypothesis-space property, additional data or larger models will not remove it, motivating an architectural repair that removes the shape-prior solution by construction.

Adam Haroon, Anush Lakshman, Cody Fleming +1

Department of Mechanical Engineering, Iowa State University, 2529 Union Drive, Ames, 50011, Iowa, USA · College of Engineering, University of Georgia, 597 D. W. Brooks Drive, Athens, 30602, Georgia, USA

Vision-Language Reprojection Consistency 3D Priors Signal-To-Noise Ratio Diagnosis

Jun 12, 2026cs.CV

Encoder Winners Do Not Reliably Transfer Across VLA Backbone Scale: A Frozen-Backbone Grafting Diagnostic

Vision-language-action (VLA) policies typically inherit their vision encoder from upstream VLM releases, but it is unclear whether an encoder choice validated on a small VLA transfers to a larger backbone. We introduce a frozen-backbone grafting diagnostic: the vision tower of a released VLA is replaced by a candidate encoder under a fixed protocol (adaptive average pooling, LayerNorm, and a single trainable linear projector), with the language model and action expert frozen. Across four encoders, two LIBERO suites, two backbones (SmolVLA-450M and

π_{0.5}

-3.3B), and two-to-three seeds per cell (40 main grafting runs plus native, LoRA, pooling, and zero-/shuffled-image controls, all scored by offline action MSE), the small-backbone winner does not reliably select the large-backbone top tier: SigLIP is best on SmolVLA across both suites, while on

π_{0.5}

DINOv2-small leads the spatial suite and the object suite is a seed-sensitive near-tie band; three of the four backbone-suite comparisons (and 11 of 12 seed-level cells) support backbone-dependent rankings. The grafting wrapper is itself non-neutral with opposite sign across backbones (+45-56% MSE on the SmolVLA native tower, -50-52% on

π_{0.5}

), so all conclusions are conditional on the fixed grafting protocol. We position frozen grafting as a cheap target-backbone diagnostic to run before committing to an encoder at scale, not as a closed-loop deployment claim.

Qingping Zeng, Fei She

Tsinghua University

Sentence Encoders Encoders Diagnosis

Jun 11, 2026eess.IV

Full-Self Diagnostics (FSD): Physics-Grounded Visual Biomarker Inference from Smartphone Video via Inverse Problems and Operator Learning

We present Full-Self Diagnostics (FSD), a unified mathematical framework for recovering latent physiological states from unconstrained 9-second facial videos captured by consumer smartphones. The approach integrates five mutually reinforcing components: (1) a physics-based forward model derived from the radiative transfer equation and chromophore absorption that maps camera observables to biomarker concentrations; (2) an information-theoretic observability theory proving that multi-channel visual signals (spectral, pulse, respiratory, micro-expression, and oculomotor) contain strictly increasing mutual information with physiological state; (3) a stable, Tikhonov-regularized inverse problem with domain-uniform identifiability guarantees; (4) an operator-learning formulation that enables generalization across devices, resolutions, and populations; and (5) a supervised learning procedure, interpretable as stochastic variational inference, that continuously refines the model from paired biosensor ground truth with performance improving proportionally to one over the square root of the number of paired observations. Empirical validation on 38812 real-world paired scans across 59 subjects demonstrates practical performance. Self-collected data from the lead author (glucose range 35-550 mg/dL) yields MARD of 29.86 percent with 97.57 percent of predictions in Clarke Error Grid Zones A+B and only 0.27 percent in the dangerous Zone E. A well-managed diabetic participant achieves MARD of 17 percent in the narrower 70-180 mg/dL band. These results confirm that consumer-grade facial video encodes sufficient structured information for clinically relevant, non-invasive biomarker inference under fully unconstrained conditions, with performance scaling predictably as more paired data becomes available.

Jonathan Thomas, Harsh Thaker

Algomash® (Algorithmic Mashup Inc.)

Physiological Data Biomarker Smartphone Photographs Diagnosis Inverse Problem Variational Inference

Jun 9, 2026cs.CV

FADA: Accessible fetal ultrasound interpretation and annotation with a selectively distilled unified vision-language model

A global shortage of trained sonographers limits prenatal ultrasound screening in low- and middle-income countries, where over half of pregnant women receive no skilled sonography. Current deep learning approaches address detection, segmentation, or classification in isolation, each demanding a separate model and expert-specified labels at inference. We present FADA, a unified vision-language model built on Qwen3.5-VL that performs clinical interpretation, classification, detection, and segmentation through a single interpretation-first pipeline without external labels. FADA distills knowledge from four domain-specific foundation models (FetalCLIP, UltraSAM, USF-MAE, UltraFedFM) via offline pre-computed feature caching. Selective distillation, which applies feature alignment only to annotation tasks while interpretation relies on standard fine-tuning, consistently outperforms full distillation across most evaluation axes. The recommended variant, FADA-SKD, achieves 0.8820 mean Dice for segmentation, 0.7671 mAP@0.50 for detection, and 100% structured interpretation compliance. Expert sonographer validation across 237 images confirms clinically acceptable outputs in both autonomous and human-in-the-loop modes, with 73.5% of interpretations scoring perfectly under clinician guidance. The system is trainable on a single consumer GPU and deployable without cloud connectivity. We validate edge deployment by running the compressed 0.8B model on a commodity smartphone (Qualcomm Snapdragon 7 Gen 1, 12 GB RAM) using llama.cpp with GGUF quantization, completing the full 5-phase pipeline in approximately 60 seconds entirely offline. This establishes a practical pathway for integrating AI-assisted fetal assessment with portable ultrasound devices, directly addressing diagnostic access gaps in resource-constrained settings. Code, models, and data are available at https://github.com/mahmoodphd/FADA.

Mahmood Alzubaidi, Uzair Shah, Raden Muaz +6

College of Science and Engineering , Hamad Bin Khalifa University,2026 Doha, Qatar. · Center for Clinical Precision Medicine and Genomics, HMC, Doha, Qatar.Jun · 3Advanced AlRazi Diagnostic Center, Al-Hodeidah, Yemen. +1

Prenatal Ultrasound Fundus Images Recent Vision-Language Models Diagnosis Deep Learning Annotations+1

Jun 9, 2026eess.AS

Optimizing 2D Input Representations and Sub-phase Fusion Strategies for Differential Diagnosis of Asthma and COPD Using CNN- and GRU-Based Networks

This study aims to explore the performance of the VAR model in comparison with mel-frequency cepstral coefficient (MFCC) matrices and log-mel spectrograms using deep learning. In pulmonary sound classification, spectrogram-based representations suffer from inconsistent temporal dimensions due to varying respiratory cycle durations. Along with traditional trimming/zero-padding, adaptive-length windowing was presented to fix their temporal dimensions. Their spectral and temporal dimensions were optimized by testing a range of parameters. Different convolutional neural network (CNN) architectures were employed to extract features from the two-dimensional representations obtained over the sub-phases. The extracted sub-phase features were then fused using various strategies including direct concatenation, gated recurrent unit (GRU) network and GRU with attention mechanism. Model performances were assessed through respiratory cycle-based evaluation and subject-based evaluation comprising multiple respiratory cycles. Several data augmentation techniques were also studied to cope with limitations in data size. The best cycle-based F1-score (0.877) was obtained using the MFCC matrices with thirteen coefficients and 64-point time resolution per sub-phase representation followed by direct feature concatenation, and the best subject-based F1-score (0.855) was obtained using the MFCC matrices with thirteen coefficients and 256-point time resolution per full-cycle representation, both obtained by adaptive-length windowing. Augmentation degraded the performance of models overall, yet mixup augmentation was the best among the methods tested. MFCC outperformed log-mel spectrogram and VAR model in differentiation of asthma and COPD. Sophisticated fusion strategies did not improve the diagnosis. Augmentation did not contribute, demonstrating the significance of authentic data in pulmonary sound studies.

Ipek Sen, Ozgur Ozdemir, Elena Battini Sonmez

Dept. Electrical and Electronics Engineering Istanbul Bilgi University, Turkey · Dept. Computer Engineering Istanbul Bilgi University, Turkey

Respiratory Sound Classification Spectral Features Direct Feature Fusion Visual Autoregressive Models Diagnosis

Jun 9, 2026cs.CV

Patient-Level Diagnosis of Acute Myeloid Leukemia via Deep Learning Analysis of Bone Marrow Smear

Bone marrow smear review remains important for acute myeloid leukemia (AML) assessment, but manual single-cell interpretation is labor-intensive and patient-level diagnosis requires aggregation of many cellular observations. We present a cell-to-patient deep learning pipeline for AML-assisted diagnosis from bone marrow smear images. The study included 258 patients from six anonymized centers, including a main cohort of 169 patients from Centers 1-3 and an external validation cohort of 89 patients from Centers 4-6. A 16-category cell annotation vocabulary was used to describe the global cellular composition, including granulocytic, monocytic, erythroid, lymphoid, eosinophilic, and other cells. Rather than identifying strict AML blasts or leukemic blasts, the model targets an expert-defined composite category termed Composite Blast-like Cells (CBLC), comprising N, N1, M, M1, R, R1, J, and J1 according to the project-wide morphological standard. A fixed YOLO-based segmentation module detected cells, predicted contours were matched to expert polygon annotations by contour IoU, and standardized single-cell crops were generated. An EfficientNet-B0 classifier was trained through a two-stage GT-to-YOLO and YOLO-to-YOLO strategy with class-imbalance correction, center-border regularization, and morphology-assisted supervision. Cell-level predictions were aggregated into patient-level CBLC ratios for AML-oriented diagnostic support. The pipeline achieved stable internal validation and maintained external generalization, with ensemble weighted F1-scores of 0.9076, 0.8696, and 0.9124 on Centers 4, 5, and 6, respectively.

Yuqi Ma, Tianyi Wang, Weihua Meng +6

State Key Laboratory of Nuclear Physics and Technology, School of Physics, Peking University, Beijing 100871, China. · Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing 100044, China. · Shanghai Dishuo Beiken Biotechnology Co., Ltd., Building 9-10, No. 3377 Kangxin Highway, Pudong New Area, Shanghai 201315, China.

Acute Myeloid Leukemia Cancer Detection Diagnosis

Jun 8, 2026cs.LG

When Do Local Score Models Extrapolate Across Size? A Diagnostic Theory and Benchmark

Scientific generative modeling often requires size transfer, where models trained on small systems are evaluated on larger ones. While translation-invariant architectures enable this evaluation, we show that architectural locality alone does not guarantee stable size extrapolation. Instead, stable extrapolation is governed by the quasi-locality of the Gaussian-smoothed score. Through Tweedie's formula, far-away perturbations can influence local score components via posterior covariance, meaning a local model succeeds only if its receptive field covers the smoothed score's response range. We formalize this mechanism, proving a size-uniform comparison theorem for local marginals under reverse diffusion. We also introduce Finite-Depth Local Flow (FDLF), a white-box diagnostic benchmark with exact scores, densities, and controllable response ranges. Empirically, we validate the interplay between spatial mixing, smoothed-score quasi-locality, and model receptive fields. Under spatial mixing, the smoothed score remains quasi-local relative to the receptive field, enabling stable extrapolation. Conversely, when spatial mixing weakens, the score's locality rapidly degrades, causing size transfer to fail.

Wenjie Xi

Department of Physics and HK Institute of Quantum Science & Technology The University of Hong Kong, Pokfulam Road, Hong Kong, China

Model Size Extrapolation Model Evaluation Generative Models Multiscale Scores+1

Jun 8, 2026cs.CL

LexRubric: A Rubric-Guided Diagnostic Benchmark for Open-Ended Legal Tasks

As large language models (LLMs) are increasingly applied to real-world legal tasks, evaluating the reliability of their open-ended legal responses has become essential. These tasks require context-sensitive answers and allow little room for error, motivating fine-grained and diagnostic evaluation that can identify specific sources of response quality failures. We introduce LexRubric, a rubric-based benchmark for evaluating open-ended Chinese legal tasks. LexRubric contains 649 instances from legal consultation and judicial examination, which reflect both everyday legal needs and professional legal reasoning and cover 14 legal scenarios. It further includes 12,337 expert-written atomic scoring criteria organized under a unified six-dimensional framework, enabling accurate evaluation and diagnostic analysis across tasks and evaluation dimensions. To validate the reliability of the evaluation, we test multiple judge models and compare model-based judgments with human judgments. We further evaluate 18 recent general and legal-domain LLMs on LexRubric. Results show that different models exhibit distinct capability profiles, and that open-ended legal tasks remain challenging for current LLMs. Data is available at: https://github.com/foggpoy/LexRubric.

Yifan Chen, Haitao Li, Yiran Hu +6

1Beijing University of Posts and Telecommunications · 2Tsinghua University · University of Waterloo +1

Legal Reasoning Tasks Task-Specific Rubrics Diagnostic Benchmark Diagnosis

Jun 8, 2026cs.CL

PACT: Learning Diverse Diagnostic Strategies via Privileged Synthesis and Branch Consensus

Clinical diagnosis requires flexible use of multiple reasoning paradigms under incomplete patient information. Existing LLM-based medical agents show strong medical reasoning ability, but single-paradigm or naively mixed dialogue supervision makes these paradigms difficult to learn without interference. We propose \textbf{PACT} (Periodic Anchor Consensus Training), a framework that couples supervised multi-paradigm dialogue synthesis with consensus-based Branch training. At the data level, \textbf{DPS} (Doctor-Patient-Supervisor) uses complete electronic medical records (EMRs) for quality control while keeping the doctor agent restricted to patient-visible information. This produces validated dialogues under four diagnostic reasoning paradigms without leaking hidden clinical answers. At the training level, PACT trains one paradigm-specific LoRA Branch per paradigm and periodically aggregates Branches into a shared Anchor through sign consensus. We further construct a dynamic multi-turn Chinese medical diagnosis benchmark for interactive consultation. Experiments show that PACT achieves state-of-the-art performance among compared proprietary, medical-specialized, and task-adapted baselines on diagnostic outcome and consultation-process metrics.

Gen Li, Yuanze Hu, Zhichao Yang +10

Beihang University · Baidu · ByteDance +2

Diagnosis Privileged Context Synthesis

Jun 8, 2026cs.CV

A multi-agent system for spine MRI report generation from multi-sequence imaging

Spinal pathology is a leading cause of pain and disability worldwide. Spine MRI is central to clinical evaluation, yet its interpretation remains complex and time-consuming, requiring integration of information across multiple imaging sequences and anatomical regions. Despite recent advances in automated MRI analysis, effectively combining multi-sequence data while preserving sequence-specific diagnostic information remains an open challenge. Here we present SpineAgent, a multi-agent framework for spine MRI report generation built upon a multi-sequence foundation model trained on routine clinical data from 32,047 patients and 453,683 MRI series, comprising a total of 13,441,191 MRI slices. To accommodate diverse modalities of sequences, we first pre-train two DINOv3-based encoders separately on T1- and T2-weighted sequences. We then introduce a continual training strategy that learns a synthesizer to embed images of other sequences using the T1 and T2 encoders, producing patient-level embedding that integrates various signals across MRI sequences. Using these embeddings, SpineAgent achieves state-of-the-art performance, and demonstrates strong generalizability under cross-manufacturer and cross-cohort evaluation. Beyond classification, SpineAgent enables pathology localization by identifying findings-relevant slices and segmenting pathological regions. It also supports multimodal image-report retrieval, providing a solid foundation for scalable and explainable MRI report generation. We further integrate these validated capabilities of SpineAgent into 37 specialized agents. Finally, we incorporate their outputs as structured tokens within a Medical Report Agent trained end-to-end for report generation. Through both automated metrics and expert evaluation by five radiologists, SpineAgent achieves leading performance in spine MRI report generation.

Zhiping Xiao, Junwei Yang, Gongbo Sun +12

1Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA, USA · School of Computer Science, Peking University, Beijing, China · Department of Computer Sciences, University of Wisconsin–Madison, Madison, WI, USA +3

Magnetic Resonance Imaging Dataset Multimodal Clinical Data Report Diagnosis Digital Pathology Encoders

Jun 7, 2026cs.SE

Auditable Graph-Guided Root Cause Analysis for Kubernetes Incidents

Kubernetes incidents are diagnosed reliably only when a root-cause system's reported gains come from incident evidence rather than scenario-specific shortcuts. We present Graph Traversal Agent, a graph-guided RCA agent that combines LLM reasoning with specialized tools. The model reasons over a typed evidence graph, while deterministic graph and tool operations collect evidence, bound the search, and check proposed verdicts. We map operational constraints, including read-only evidence collection, propagation-aware diagnosis, bounded execution, and independently validated verdicts, to a typed incident graph, a LangGraph traversal state machine, and a separate validation stage. On ITBench snapshots scored by one fixed qwen-plus judge, the audited system raises root-cause-entity F1 over an earlier iteration of the same system from 0.6087 to 0.9130 on a 23-scenario common subset. A prompt-level ablation separates prompt-tuned gains from gains that survive once scenario-specific hints are removed: the stripped-prompt configuration retains 0.6958 F1 on a 19-scenario subset. The surviving gain concentrates on ChaosMesh scenarios whose ground-truth root cause is the injected fault object already present in the evidence graph, so we report it as benchmark-coupled rather than broad cross-cluster RCA evidence. Lightweight checks, including same-judge comparison, prompt-level ablation, cascade-source checking, and a telemetry no-leak test, mark claims as supported, pending, or out of scope. We scope the work to ITBench OpenTelemetry-demo snapshots. Live-cluster trials served as an engineering stress test, but alert state and trace availability did not stay stable enough for controlled scoring, so we make no production-readiness or mean-time-to-repair claim.

Anastasiia Kuvshinova, Seungmin Jin

HSE University Moscow, Russia

Root Cause Analysis Reasoning Graphs Causal Graph Multivariate Telemetry Data Diagnosis

Jun 5, 2026cs.CL

Beyond English benchmarks: clinical llm evaluation in Brazilian Portuguese

Large Language Models are transforming the support for clinical decision and their application in real scenarios. Yet, most benchmarks are conducted in English, and cross-lingual evaluation is needed to tackle the language gaps in global access. We introduce ClinicalBr, the first bilingual benchmark for clinical decision built from real Brazilian case reports. The corpus contains 2,892 cases drawn from 28 SciELO medical journals, spanning 18 specialties, and is structured as parallel Portuguese-English pairs. Each case supports four evaluation tasks: diagnosis retrieval, differential diagnosis, exam recommendation, and treatment planning. We evaluate four models: MedGemma-27B, Sabiá-4, DeepSeek-R1, and o3-mini, across both languages. The central finding is that the Portuguese-English performance gap is task-dependent, not general. In diagnosis retrieval, English yields a consistent advantage across all models, with +7.5-12.1 accuracy points. This advantage disappears in differential diagnosis, exam recommendation, and treatment planning, where confidence intervals cross zero for most models and Portuguese completeness scores are marginally higher. Brazilian-endemic conditions proved easier than the full corpus, not harder, indicating that tropical presentations are adequately represented in current pre-training. Exam recommendation was the hardest task across all models and both languages, with F1 scores below 0.10, well below the differential diagnosis ceiling of 0.20-0.27.

Giordano de Pinho Souza, Glaucia Melo, Josefino Cabral Melo Lima +1

Federal University of Rio de Janeiro · Toronto Metropolitan University Toronto, CA

Portuguese Multilingual Benchmark Diagnosis Large Language Models(Llms

Jun 5, 2026cs.LG

When Attribution Patching Lies: Diagnosis and a Second-Order Correction

A central goal of mechanistic interpretability is to identify which internal components causally drive a language model's behavior. Because these importance estimates serve as the evidence for identifying circuits, systematic errors can lead to the misidentification of the underlying mechanisms. While activation patching provides a gold-standard causal metric, its computational cost is prohibitive at scale. Practitioners instead rely on attribution patching, a gradient-based, first-order approximation whose reliability remains poorly understood. In this work, we characterize the source of this unreliability, demonstrating that the dominant error stems from the non-linearities in the downstream network rather than local curvature at the patched component. This insight yields three practical tools: (i) a reliability score to detect untrustworthy estimates, (ii) error bounds quantifying potential attribution mis-specifications, and (iii) a Hessian-vector-product (HVP) correction that eliminates the leading-order error with only one additional backward pass. In evaluations across five model families (124M-9B parameters) and both random-token and naturalistic (name-swap) perturbations, HVP is the only second-order correction feasible at larger scale, where standard baselines like Integrated Gradients become computationally prohibitive. In comparative experiments, a multi-step HVP variant matches or exceeds the accuracy of Integrated Gradients at significantly lower compute, outperforming prior second-order baselines. These improvements lead to higher-fidelity circuit recovery on standard benchmarks and support a Screen-Flag-Fix workflow that targets computational effort only toward the components flagged as unreliable.

Luyang Zhang, Jialu Wang

1Carnegie Mellon University · University of California, Santa Cruz

Mechanistic Interpretability Correction Diagnosis

Jun 5, 2026cs.LG

Evidence-Grounded Ensemble Diagnosis of 802.11 Packet Captures: A Multi-Stage Pipeline with Deterministic Reliability Scoring

Diagnosing 802.11 packet captures requires expert protocol knowledge, is slow, inconsistent across engineers, and unscalable. LLM-based approaches sound plausible but fabricate protocol events absent from captures (especially truncated traces), produce uncalibrated confidence scores, and suffer evaluation bias when golden references are co-produced by the model under test. We introduce PROBE (Protocol Reasoning Over evidence-Based Ensembles), a multi-stage pipeline addressing all three failures. It integrates (i) deterministic PCAP-to-text normalization with frame-level verifiability, (ii) multi-run, multi-candidate ensembles with optional cross-model second opinion and progressive obfuscation, (iii) a verdict-aware evidence framework treating absence of failure evidence as contributing evidence, and (iv) a fully deterministic composite reliability score from evidence validity, run-to-run stability, and cross-model agreement without LLM self-assessment. On 87 enterprise Wi-Fi captures (104 capture-reviewer pairs), single-pass LLM analysis raises weighted evidence F1 from 0.871 (expert baseline) to 0.912 but misses critical frames in 35% of cases. Naive ensemble voting drops below baseline (0.842) as majority voting amplifies conservative verdicts: 50% of confirmed failures are misclassified as 'no issue' or 'insufficient evidence.' Adding evidence-grounded reconciliation achieves 0.957 F1, a 96% auto-accept rate, and a worst-case floor above 0.70. LLM self-reported confidence clusters at 0.95 regardless of difficulty (71% report exactly 0.95), confirming it is uninformative. We also introduce a model-agnostic evaluation framework using per-field assertion matching, eliminating circular bias from model-co-produced golden references.

Jerome Henry, Swadhin Pradhan, Miroslav Popovic

Cisco Systems

Capture Protocol Evaluation Protocols Diagnosis Wifi Ensemble

Jun 4, 2026cs.CL

Diagnosing Evidence Utilization in Long-Context and Retrieval-Augmented Language Models under Matched Evidence Conditions

Final-answer accuracy, retrieval recall, and citation overlap do not reveal how much answer advantage a long-context or retrieval-augmented language model actually recovers from supplied evidence. A model may answer from parametric priors, fail to use evidence that is present, or cite relevant text without converting it into the final answer. This paper introduces a four-condition diagnostic protocol for evidence-utilization evaluation under matched examples, models, prompts, and scoring rules. The protocol compares no-evidence, full-context, retrieved-evidence, and oracle-evidence reference conditions, and uses Oracle-Reference Normalized Context Utilization (ONCU) as a denominator-valid estimate of recovered oracle-reference evidence advantage. The empirical study evaluates five local open-weight models from the Qwen, Gemma, Llama, and Mistral families over Controlled-ONCU-safe16K, HotpotQA-ONCU, and 2WikiMultiHopQA-ONCU, comprising 18,000 ONCU-compatible predictions. Results show a task-dependent diagnostic pattern: controlled synthetic settings expose reduced recovery when the same evidence is embedded in long input rather than supplied compactly, while realistic multi-hop reconstructions show that full-context inputs outperform the tested retrieved inputs in denominator-free answer and evidence metrics, with ONCU supporting the same direction on oracle-improving groups. Sensitivity audits with stronger retrieval settings narrow some gaps but do not overturn the scoped interpretation. The main contribution is therefore not a single utilization ratio, but a matched diagnostic protocol that separates no-evidence answerability, oracle-evidence recoverability, full-context recovery, retrieval-conditioned recovery, denominator validity, and companion answer/evidence diagnostics.

Haizhou Xia

University of Western Ontario, Canada

Question-Answering Benchmarks Answer Diagnosis

Jun 4, 2026cs.AI

Integrating Mechanistic and Data-Driven Models for Neurological Disorders through Differentiable Programming

Advances in computational modeling, neuroimaging, and artificial intelligence are revolutionizing the modeling of neurological disorders for improved diagnostics, prognosis, and treatment planning. Mechanistic models provide valuable scientific insight into the disorders, but in practice they are often simplified with assumptions or computationally expensive and slow to solve. However, while purely data driven approaches provide speed and scalability, they require large, high quality data to train and generally suffer from interpretability and generalization issues. This perspective paper presents a structured overview of hybrid modeling strategies, which combine deep learning models with physics based solvers, and are categorized into parallel, series, and parallel-series architectures. Three main approaches that have been emphasized are residual modeling for missing or incomplete physics, Neural Ordinary Differential Equations (NODEs) for continuous time dynamics approximation, and solver in the loop that accelerates traditional solvers with neural approximations. These hybrid models integrate the governing differential equation based formulations and deep learning to characterize the evolution of neurological disorders, and promise advanced personalized neurological modeling. In addition, the study explores and proposes different hybrid configurations to improve diagnosis accuracy, predict disease progression, and inform treatment strategies across a range of neurological disorders. These capabilities outperform standalone mechanistic or purely data driven approaches, making hybrid modeling a powerful tool, especially in applications involving modeling the progression and treatment responses in neurological conditions such as brain tumors, Alzheimer's disease, and stroke.

Shah Pallav Dhanendrakumar, Saikat Pal, Sitikantha Roy

Department of Applied Mechanics, Indian Institute of Technology Delhi, New Delhi-110016, India · Yardi School of Artificial Intelligence, Indian Institute of Technology Delhi, New Delhi-110016, India

Data-Driven Diagnosis Treatment

Jun 4, 2026cs.CV

UltraVR: A Diagnostic Ultra-Resolution Image-VQA Benchmark for Evidence-Grounded Reasoning

Vision-language models (VLMs) excel on visual question answering and multimodal reasoning benchmarks. Yet their capability on ultra-resolution images - where critical evidence is tiny, subtle, spatially distant, or distributed - remains unclear. Existing evaluations largely report final-answer accuracy, offering limited insight into whether models acquire and integrate the necessary visual evidence. We introduce UltraVR, a diagnostic benchmark for evidence-grounded visual reasoning over ultra-resolution images. UltraVR spans four high-value scenarios: CCTV surveillance, remote sensing (RS), whole-slide image (WSI) pathology, and industrial anomaly detection (AD). These domains pose complementary challenges: fine-grained object grounding in crowded CCTV scenes, long-range spatial comparison in RS, multi-scale evidence navigation in WSI, and subtle irregularity detection in repetitive industrial layouts. Beyond standard QA triples, each instance includes a structured ground-truth chain of thought with step-level questions, intermediate answers, and reasoning labels. These labels decompose reasoning into evidence grounding, local perception, quantification, evidence integration, and decision inference, enabling process-level diagnosis over black-box scoring. Using UltraVR, we evaluate frontier VLMs and show that current models remain far from reliable on ultra-resolution reasoning. Importantly, the structured annotations allow us to localize failures across the visual-to-decision pipeline: errors concentrate in evidence grounding and local perception, while downstream inference often recovers when intermediate visual facts are supplied. These findings demonstrate UltraVR as a diagnostic testbed for measuring not only whether VLMs answer correctly, but where their ultra-resolution reasoning process breaks.

Gexin Huang, Yanting Yang, Myeongkyun Kang +6

University of British Columbia, Vancouver, BC, Canada · Vector Institute, Toronto, ON, Canada · The Hong Kong Polytechnic University, Hong Kong SAR, China +1

Multimodal Reasoning Benchmarks Visual Reasoning Ultrafast Diagnosis

Jun 4, 2026cs.CL

Domain-Aware Mispronunciation Detection and Diagnosis Using Language-Specific Statistical Graphs

Mispronunciation Detection and Diagnosis (MDD) has gained increasing importance in computer-assisted language learning and speech technology in recent years. In this paper, we propose a method for constructing statistical graphs that enable models to learn phoneme confusion patterns represented as directed graphs. Furthermore, we introduce a language-specific strategy to capture systematic pronunciation differences across various native language (L1) backgrounds. The effectiveness of our approach is demonstrated through extensive experiments on the L2-ARCTIC benchmark, where it achieves an F1-score of 59.52%, outperforming several competitive baselines.

Huu Tuong Tu, Hanh Nguyen, Thien Van Luong +3

1Hanoi University of Science and Technology · 2VNPT AI, VNPT Group · 3National Economics University

Pronunciation Assessment Grapheme-To-Phoneme Diagnosis Chart

Jun 3, 2026cs.DC

Ekka: Automated Diagnosis of Silent Errors in LLM Inference

LLM serving frameworks are quickly evolving with a complex software stack and a vast number of optimizations. The rapid development process can introduce silent errors where output quality silently degrades without any explicit error signals. Diagnosing silent errors is notoriously difficult due to the substantial semantic gap between the high-level symptoms and the low-level root causes. We observe that diagnosis of silent errors can be effectively framed as a differential debugging problem by leveraging the existence of semantically correct reference implementations. We propose Ekka, an automated diagnosis system that identifies root causes by systematically aligning and comparing intermediate execution states between a target and a reference framework. We constructed a benchmark of real-world silent errors from popular serving frameworks, where Ekka shows 80% pass@1 diagnosis accuracy and 88% pass@5 diagnosis accuracy, outperforming state-of-the-art systems. Ekka also diagnoses 4 new silent errors from serving frameworks, all of which have been confirmed by the developers.

Yile Gu, Zhen Zhang, Shaowei Zhu +4

University of Washington · 2Amazon Web Services.

Diagnosis Large Language Models(Llms Intermediate States

Jun 3, 2026cs.CV

Motion-Guided Causal Disentanglement for Robust Multi-View Cine Cardiac MRI Diagnosis

Multi-view cardiac magnetic resonance (CMR) imaging provides complementary anatomical information and is widely used for noninvasive disease assessment. Recent transformer-based models have demonstrated strong representation learning capabilities for CMR analysis; however, they typically learn unified latent embeddings that entangle view-specific anatomical variations with disease-related features. Such entanglement biases classifiers toward structural attributes rather than view-invariant pathological patterns. This issue is exacerbated in low-data regimes, particularly for underrepresented cardiac conditions, where limited samples increase the susceptibility to shortcut learning and view-dependent decision boundaries. To address this, we propose a Motion-Guided View--Disease Disentanglement framework MoViD built upon a ViT-MAE backbone. The model explicitly factorizes latent representations into view-specific and disease-discriminative components using dual-branch supervised contrastive objectives and a gradient-reversal adversarial constraint that minimizes disease leakage into the view embedding. Additionally, an annotation-free temporal motion feature, derived from inter-frame difference maps, is introduced to localize the beating heart region and suppress background artifacts. A focal reweighting mechanism is incorporated into the contrastive loss to mitigate class imbalance. We evaluate the framework on a private clinical venous thrombosis dataset and two public benchmarks (M&Ms, M&Ms2). Across disease classification and cardiac segmentation tasks, our approach consistently outperforms standard transformer baselines and demonstrates competitive performance against large-scale pretrained foundation models, validating the efficacy of structural disentanglement in medical image analysis.

Chuankai Xu, Cristiane De Carvalho Singulane, Mohammad Abuannadi +10

University of Virginia, Charlottesville, VA, USA · University of Chicago, Chicago, IL, USA · Ohio State University, Columbus, OH, USA +5

Cardiac Magnetic Resonance Imaging Echocardiography Multi-View Contrastive Loss Diagnosis Causal

Jun 2, 2026cs.AI

Gender-Dependent Diagnostic Substitution in LLM Medical Triage: Same Symptoms, Unequal Urgency

We investigate whether large language models produce different medical triage recommendations for identical neurological symptoms when only the patient's stated gender and age vary. Using three model families--Gemini 3.5 Flash, Claude Sonnet 4.6, and GPT-5.4-mini--we present a standardized symptom profile (persistent headache, blurred vision, morning nausea, visual disturbances) across seven demographic conditions: three age groups (25, 38, 65) x two genders (male, female), plus a gender-unspecified baseline (n = 30 per condition per model, 630 total trials). We find a stark, systemic gender-dependent triage disparity: young women receive significantly lower emergency room (ER) referral rates than age-matched men (Gemini: 0% vs. 23.3%; Claude: 6.7% vs. 96.7%; GPT: 6.7% vs. 66.7%, all p < 0.001). The disparity disappears at age 65 for all models. The primary mechanism is diagnostic substitution: the models anchor on a gender-associated diagnosis, preferentially classifying young women with Idiopathic Intracranial Hypertension (IIH)--a condition epidemiologically linked to women of childbearing age--while diagnosing men with generic increased intracranial pressure with space-occupying lesions in the differential. This diagnostic closure routes female patients to lower-urgency care (outpatient doctor appointments) despite comparable severity ratings (7-9/10). Our findings demonstrate that clinical LLMs replicate documented human clinical biases by using epidemiological priors to suppress triage urgency, suggesting that AI triage engines must decouple urgency assessment from probabilistic diagnostic priors. We release all code, prompts, and raw results.

Qi Han Wong

Triage Diagnosis Disparities Age Epidemiological Models

Jun 2, 2026cs.LG

Analyzing Stream Collapse in Hyper-Connections: From Diagnosis to Mitigation

Hyper-Connections (HC) replace the single Transformer residual stream with multiple streams, introducing a permutation symmetry over stream indices. We study how this symmetry is resolved in practice: whether streams specialize in a balanced way or exhibit dominant-stream usage. Using fine-grained diagnostics for HC-based language models, we trace how multi-stream representations are actually used. We find that after an early seeding stage, residual mixing often remains close to identity, limiting a core HC mechanism for exchanging information between streams. Moreover, both signal and interpretable features concentrate in a dominant stream, and the nominally multi-stream residual connection can underutilize its capacity, behaving closer to a single-stream residual pathway. Finally, we show that breaking symmetry at stream initialization reduces dominant behavior and improves performance across \textit{m}HC variants. Our code is publicly available.

Ekaterina Alimaskina, Gleb Molodtsov, Aleksandr Beznosikov

1MIRAI, Moscow, Russia · 2BRAIn Lab, Moscow, Russia · 3Yandex Research, Moscow, Russia +1

Text Dominance Diagnosis