Transmissive X-Ray Imaging

X-ray is medicine's most widely used imaging modality, yet remains among its least quantitative. Unlike volumetric modalities like CT or MRI, X-ray collapses 3D anatomy into a 2D projection, causing structures to overlap and anatomical boundaries to be ambiguous, even to experts. As a result, labeling X-ray databases for training general-purpose segmentation systems is impractical, leaving morphometric and functional X-ray analysis confined to narrow anatomical regions and applications. To this end, we present FleXray, a generalist model for anatomical segmentation across the entire body in clinical X-rays. Instead of curating large, manually annotated X-ray datasets, we build a scalable, physics-based generative X-ray data engine. Using existing 3D whole-body CT segmentation datasets and generative image-editing models, we simulate fully-annotated 2D X-rays with diverse appearances, physiological properties, and imaging geometries. Trained on these simulations, FleXray accurately segments 60 anatomical structures across unseen research datasets and in-the-wild X-rays. We further show that FleXray makes X-rays directly amenable to quantitative analysis, enabling automated measurements for disease grading, robust navigation during X-ray-guided interventions, and data-efficient learning of pathological targets. We release the model, code, a full-body X-ray segmentation dataset, and a local, easy-to-use browser-based tool at https://flexray.csail.mit.edu .

Prohibited-item detection in X-ray imagery remains challenging due to object superposition, weak texture, and material clutter which obscure both semantic appearance and object boundaries. We propose \textbf{DERA}, a \textbf{D}etached \textbf{E}dge-\textbf{R}esidual \textbf{A}daptation framework for prohibited item detection under X-ray imagery. DERA combines hierarchical visual features with a parallel pixel-difference edge pyramid and learns an object-specific boundary prior from training-time contours of the instance masks. The detached prior gates edge-sensitive features, which are injected into the early visual stages through residual heads. This staged design preserves the foundation detector at the start of adaptation, isolates boundary supervision from semantic feature learning, and restricts the final adaptation stage to only $14.7$K trainable parameters. Evaluated on PIDray, CLCXray, and STCray, DERA improves the baseline by \textbf{3.1}, \textbf{1.6}, and \textbf{2.4} AP points, respectively.

Sparse-view X-ray 3D reconstruction is essential for reducing radiation exposure, but recovering a density field from a handful of X-ray projections is severely ill-posed. Recently, 3D Gaussian Splatting has achieved state-of-the-art performance in sparse-view reconstruction by representing the volume using explicit, optimized primitives, but it requires dozens of projected views. With fewer views, reconstruction quality degrades severely since the explicit primitives are optimized freely without any anatomical information. Anatomical structures, in contrast, share similar geometry and density across a population. Their variations are bounded within a limited range that statistical shape models can capture. This paper proposes a shape-guided Gaussian splatting framework for sparse-view X-ray 3D reconstructions. Our contribution lies in driving Gaussian positions toward anatomically valid configurations, alongside atlas-based density regularization. Our method ensures anatomically consistent reconstruction and improves PSNR by 2.83 dB over a state-of-the-art Gaussian splatting baseline with as few as 5 views. Code Available: https://github.com/polyshape-lab/ShapeGuidedGaussian

Three-dimensional femoral reconstruction from radiographs supports surgical planning, implant sizing, and post-operative follow-up, but remains ill-posed as X-ray projections discard depth information. Existing methods often incorporate a 3D statistical shape model (SSM) as a shape prior to guide reconstructions toward anatomically plausible shapes, relying on iterative 3D-to-2D projection matching. Yet, these approaches are computationally expensive and constrain their SSM to a single dimensionality, leaving the statistical relationship between 2D observations and 3D geometry largely unexploited and unexplored. We instead propose a joint 2D-3D SSM that explicitly captures the co-variation between 2D and 3D segmentations in a shared latent space. During training, 2D and 3D segmentations are registered to a common 3D template and its corresponding 2D projections, and the resulting stationary velocity fields are jointly decomposed using principal component analysis (PCA). This joint modeling allows the 2D-to-3D mapping to be learned directly from data rather than computing correspondences at inference time. For unseen subjects, the 3D shape is recovered directly by lifting the 2D latent coordinates to the 3D PCA subspace, thereby eliminating the need for iterative 3D-to-2D projection. Experiments on NMDID demonstrate that the proposed joint 2D-3D SSM outperforms a widely-used 3D-only SSM baseline while achieving inference approximately 4 times faster, at under 3 seconds per subject. The code is available at: https://github.com/florence-dellaniello-picard/joint2d3d-ssm.

Non-destructive X-ray and computed tomography (CT) testing are essential for ensuring the dimensional accuracy of manufactured components with complex internal structures, such as the cooling channels in gas turbine blades, which directly affect thermal performance and service life. This study presents a multipart 3D-2D rigid registration approach for aligning CAD models with X-ray projections as an alternative to CT reconstruction for part inspection and measurement. A greedy registration algorithm sequentially aligns the blade's exterior before registering its internal components by maximizing the mutual information between simulated and acquired X-ray images. This stepwise approach reduces problem complexity and improves alignment accuracy. View angles are optimized using a greedy method that iteratively selects angles to minimize dimensional measurement errors. The results indicate that a small number of oblique views provides the best accuracy, although a broad range of angles yields acceptable results. The method achieves subpixel registration accuracy, with errors below one-fifth of the magnified detector-pixel pitch. Image noise and defects reduce registration precision, but direct registration in projection space mitigates these effects compared with CT reconstruction. Appropriate view selection can therefore preserve acceptable subpixel accuracy in the presence of image noise and defects.

Cone-beam computed tomography (CBCT) enables volumetric reconstruction from X-ray projections, but suffers from severe artifacts--especially beam hardening--when imaging materials with high attenuation such as metals. These artifacts arise from the polychromatic nature of X-rays and are not properly addressed by conventional monochromatic reconstruction algorithms. While recent neural representation-based methods offer improved reconstruction quality, they are computationally expensive and often impractical for deployment. We propose a novel physics-inspired, self-calibrating metal artifact reduction method that efficiently reconstructs 3D CBCT volumes while correcting beam hardening artifacts. Our method integrates a polychromatic X-ray projection model, material-dependent attenuation profiles, and system response modeling into a Gaussian Splatting framework. Unlike prior work, we eliminate the need for manual metal masks or strong prior assumptions, and we optimize both reconstruction parameters and X-ray spectral characteristics jointly during training. We further introduce a high-fidelity synthetic CBCT dataset generation pipeline validated on Monte-Carlo x-ray simulation toolbox and release new datasets with severe metal-induced artifacts to support the community. This is the first splat-based method for reducing beam hardening in CBCT. Extensive experiments on both synthetic and real-world datasets demonstrate that our method outperforms state-of-the-art approaches in artifact suppression and reconstruction accuracy.

Non-destructive X-ray imaging can reveal internal hazelnut defects that are difficult to detect by external inspection alone; however, automated interpretation remains challenging because of subtle radiographic differences among classes, marked class imbalance, and limited annotated data. Here, we present a benchmark for binary hazelnut quality classification (healthy versus defective) based on 799 segmented single-kernel X-ray images (224 x 224 pixels, grayscale), grouped into 101 acquisition units. Seven single-model configurations and ten probability-aggregation ensembles were evaluated using a group-wise split-rotation protocol across five data splits generated using different random seeds. Decision thresholds were selected on the validation set, and performance was assessed deterministically on validation and test sets. Under the expert-reassessed annotation condition, the average-probability ensemble of the binary cross-entropy-trained convolutional neural network and frozen Swin Transformer achieved the highest mean balanced accuracy (86.3% +/- 1.8%, five seeds), with several other ensembles providing comparable performance. Across methods, substantial split-to-split variability was observed, indicating that multi-split evaluation is essential for reliable model comparison at this dataset scale. Expert reassessment of ambiguous samples improved the performance of all 17 evaluated methods by 2.8-8.1 percentage points, while having only a limited effect on cross-split variance. The results highlight both the potential of deep learning for automated X-ray-based hazelnut quality assessment and the importance of rigorous evaluation and label curation in small, imbalanced agricultural imaging datasets.

Multimodal industrial anomaly detection has largely focused on discrete products using strongly correlated RGB and 3D observations, leaving continuous process manufacturing and weakly correlated sensing modalities underexplored. We introduce LIBAD, the first multimodal anomaly detection benchmark for Li-ion battery electrode manufacturing. Collected from real roll-to-roll production lines, LIBAD provides aligned double-sided visible-light imaging, high-resolution X-ray radiography, and inline-compatible low-resolution X-ray radiography. Electrode patches in LIBAD exhibit highly homogeneous material appearance, while defect evidence can be strong in one modality but weak or absent in another, resulting in pronounced cross-modal anomaly inconsistency. Benchmarks of representative methods under the inline-compatible visible-light and low-resolution X-ray setting exhibit limited transferability and consistently high false-positive rates. We therefore propose DA-Core, a memory-based method that jointly considers feature-space coverage and local density of normal features during coreset selection, allowing compact memory banks to better preserve fine-grained normal variations. With a coreset ratio of 0.05, DA-Core reduces FPR95 from 60.4% to 54.3% compared with standard farthest point sampling. At this ratio, DA-Core also outperforms the best standard coreset result (obtained at 0.20) while reducing inference time by 43.9%. These results suggest that both the data distribution of normal features and the modality relationship itself require explicit consideration when designing anomaly detection methods for process manufacturing.

Time-varying implicit neural representations (INRs) provide a compact representation of scientific volumes and, for modalities such as dynamic X-ray computed tomography (CT), are often the only practical way to represent the data. However, interactive volume rendering of INRs is challenging, as cheap memory lookups are replaced by expensive neural inferences, hindering the performance. Therefore, conventional volume rendering methods such as ray marching with dense sampling are often impractical. While resampling, caching, and retraining can mitigate this cost, they compromise convenience and accuracy and become impractical for time-varying data. We tackle these challenges using a query-efficient stochastic volume rendering framework based on delta tracking. Our system employs a four-stage pipeline that exploits heterogeneous parallelism, using ray tracing cores for traversal and tensor cores for batched neural evaluation. Furthermore, we present strategies to reduce INR queries via ray budgeting and query pruning, thereby increasing per-frame performance. Using our renderer, many time-varying INRs can be rendered directly from their original representation. The system achieves ~30-40 FPS at 1024x1024 resolution on an RTX 4090 GPU and converges to high-fidelity images. Moreover, the system enables interactive temporal exploration of the continuous domain, with timestep updates taking approximately 1-2 ms.

With the increase in the number of cases related to respiratory diseases, there is an urgent need to detect them early and diagnose them accurately. Convolutional neural networks have given promising results when used for diagnosing diseases using imaging tests. In this study, we investigate the potential of applying deep learning algorithms such as VGG16, VGG19, and ResNet50 for classification of lung ailments based on X-ray images. A detailed analysis of the aforementioned models' performances was conducted to assess how well they can classify various types of lung ailments, including pneumonia, tuberculosis, lung cancer, and normal lungs. In order to do that, these deep learning models were trained on a vast amount of X-ray images. The results of our study show that while all three models provide good results, ResNet-50 performs best in comparison with other models due to its efficiency and high level of accuracy. We believe that these deep learning models can be successfully implemented in the practice of diagnosing pulmonary diseases in the future. It helps with early disease detection and improves patient outcomes.

Background. Pediatric musculoskeletal trauma represents up to 18% of pediatric ED visits, yet diagnosis still depends on ionizing radiography. Cumulative low-dose radiation in early life raises lifetime leukemia and brain malignancy risk, motivating radiation-free triage alternatives. Objective. To synthesize evidence for a hybrid framework coupling broad-spectrum infrared (IR) imaging with deep-learning cross-modal translation to generate clinically interpretable synthetic-radiograph reconstructions from non-ionizing data. Approach. We review five IR spectral windows spanning 650 nm to 1 mm - NIR-I, NIR-II, SWIR, MIR/LWIR, and THz - and how dual-geometry (transmission/reflection) acquisition exploits wavelength-specific tissue depth and biochemical sensitivity. We summarize image-to-image translation networks (Pix2Pix, CycleGAN, Swin-Unet) and feature-matching algorithms (SuperPoint, SuperGlue, ALIKED, LightGlue) used to align and fuse IR data into radiograph-equivalent reconstructions. Implications. Pediatric anatomy - smaller cross-sections, thinner cortical bone - favors IR penetration, enabling compact, portable, non-ionizing triage hardware. Feasibility is grounded in fNIRS and transcranial photobiomodulation evidence: near-infrared light passes through skin, skull, and cortex with sufficient signal for hemodynamic monitoring - a longer, more attenuating path than through a pediatric forearm or distal leg. Key barriers: paired IR/X-ray dataset construction, AI-as-medical-device regulatory pathways, generalization across body habitus and skin pigmentation, and acquisition-protocol standardization. Conclusions. Integrated multi-spectral IR+AI imaging is a promising radiation-free complement to pediatric skeletal radiography. Progress requires multi-center paired datasets, externally validated models, and IR source safety qualification under IEC 60825-1.

Recovering the 6-DoF pose of the knee bones from a plain radiograph, given the patient's segmented pre-operative CT, turns a routine low-dose image into a quantitative measurement of joint geometry, without the added dose of a repeat CT or a fixed biplanar rig. Classic solutions align a rendered bone silhouette to image edges; recent alternatives refine pose by backpropagating an image-similarity loss through a differentiable X-ray renderer. Both operate one patient at a time and are fragile under a single view. Silhouettes are depth-ambiguous, and differentiable-rendering refinement has a narrow capture range at substantial per-iteration cost. We instead learn an amortized, subject-agnostic dense 2D-3D correspondence, supervised solely by projection geometry. One shared-weight model per bone, trained across 758 patients, registers patients unseen during training. The pose then follows in closed form from a global, initialization-free, render-free PnP+RANSAC solve. Because X-ray formation is transmissive, our correspondence target is transmission-aware rather than tied to a single surface. Though trained only to register, the representation is anatomically semantic: a simple classifier reads a landmark's anatomical region from its embedding across held-out patients, and the same features separate the knee's bones into a 2D-3D-consistent identity learned without any bone label. On a large single-institution cohort the model generalizes well to held-out patients.

Radiative Gaussian splatting reconstructs sparse-view CT fast and accurately, and recent work attaches per-Gaussian posteriors to yield per-voxel uncertainty maps. We ask what such a map actually measures: posterior variance is a data-constraint map, not an error map -- its alarms are trustworthy, its all-clears are not. Exploiting the strict linearity of X-ray rendering in the per-Gaussian densities, we derive a clamp-aware closed form that the unchanged rasterizer evaluates exactly in one forward pass, in volume and projection space: the infinite-sample limit of the sampling estimator of concurrent work, at ~8x lower cost. On the official 15-scene benchmark this uncertainty ranks true error on 14 of 15 scenes. Restricted to the object interior -- the tissue a clinician reads -- the ranking collapses (median Spearman 0.11, 0/15 pass), identically for a deep ensemble and for a strictly positive log-normal posterior: three constructions, two estimator families, no survivors. The mechanism is structural: about 90% of in-object error is bias that reproduces across retrainings, invisible to model disagreement; 73-81% of the full-volume correlation is carried by object/surround contrast; and an exactly solvable control puts the observed in-object ranking 4-5x below what a perfectly calibrated posterior with the same sigma-spread would score. The error scale, by contrast, is an engineering problem, and we solve it: reparameterizing the posterior contracts the cross-scene temperature spread from 19.3x to 2.6x, one scene-agnostic temperature transfers to unseen scenes (10/15 leave-one-scene-out), and the repaired scale tracks photon count at the Poisson-predicted -1/2 power. We distill evaluation practice that would have caught the illusion -- masked calibration, seed-wise bias decomposition, an exact-posterior reference -- and release all protocols, seeds and per-run evidence.

Achieving optimal screw placement for orthopedic surgeries requires frequent alignment checks and multiple anatomical views under X-ray -- a process known as "fluoro-hunting" that increases radiation exposure to patients and surgical teams. This work introduces X-GuideAR, an augmented reality (AR) framework for identifying optimal X-ray views, aimed at reducing radiation exposure while ensuring accurate screw placement. To exemplify the benefits of X-GuideAR, we focus on S2 alar-iliac (S2AI) screw placement. Our system provides radiation-free guidance for view acquisition and drilling by generating synthetic X-ray previews that accelerate fluoro-hunting. Once the required anatomical views are identified using these previews, a real X-ray is acquired, and the preview of the drilling trajectory is augmented onto it, facilitating precise screw placement with minimal additional radiation. A preliminary study involving eight S2AI trajectories performed by an expert spine surgeon demonstrated a 62.3% reduction in the number of X-rays. Post-procedure evaluations showed that trajectories done with X-GuideAR supported an average safe screw diameter of 12.95 mm compared to 5.9 mm under the conventional workflow, suggesting improved bony containment and potential biomechanical benefit. X-GuideAR shows great potential to reduce radiation exposure and streamline S2AI screw placement, offering a promising direction toward safer and more efficient surgeries.

We present a framework to cross-match sources from the Chandra Source Catalog (CSC v2.1) with optical sources from Gaia Data Release 3. Unlike purely spatial approaches, we use source properties such as magnitudes, colors, and distances to identify true counterparts, detect chance coincidences, and resolve ambiguities when multiple plausible candidates exist. We define a training set of high-confidence matches using NWAY, a Bayesian cross-matching framework that accounts for positional errors and source densities. We train a gradient-boosted classifier (LightGBM) on a variety of features from both catalogs. Of the ~$254$k unique X-ray sources, we find counterparts for ~$113$k sources, of which plausible multiple counterparts are found for ~$7$k. We find no counterparts for ~$20$k sources for which separation-based cross-matching does find a match, and attribute half of these to chance coincidences. We validate the pipeline on the Chandra Orion Ultradeep Project (COUP), where the machine-learning matches reproduce 95% of NWAY cross-matches without using any positional information. We release a catalog of the ~$113$k Chandra-Gaia counterparts, together with ~$7$k alternative matches and ~$20$k ambiguous NWAY associations, supporting future population studies of sources detectable by both Chandra and Gaia. We discuss limitations and provide a generalization of the framework that is applicable in other cross-matching scenarios.

The need for detecting and sorting batteries is drastically increasing for many applications. This study proves the potential of transfer learning in predicting whether the image contains a battery or not, the location and identifying three types of batteries, namely: prismatic, pouch, and cylindrical Lithium-Ion Batteries (LIB). Particularly, it focuses on the transfer learning method in two applications: Training a large-scale dataset to detect electronic devices using a pre-trained YOLOv5m, then using these latter trained weights to detect and classify the batteries. The precision of battery detection achieves 94%, which outperforms the pretrained YOLOv5m weights with 5%, in 22 ms inference time.

The state-of-the-art generative models, such as CycleGAN, Pix2Pix, and diffusion models have demonstrated remarkable performance in the face generation task. However, they fail to effectively capture cross-modality semantic information in craniofacial reconstruction when translating from the skull (x-ray) to the face (optical) domain, due to a mismatch in the alignment of structural identity across modalities. To address this issue, we propose Cranio-Diff, a diffusion-based framework for cross-domain cranio-facial reconstruction from 2D X-ray skull images. The proposed approach integrates skull-conditioned structural guidance through ControlNet with biometric text conditioning to generate a face which is more semantically and structurally aligned with the given skull. The proposed Cranio-diff method is evaluated on skull-face dataset obtained from X-ray scans of 120 subjects in lateral and frontal views. To enable controlled evaluation, each face image is synthesised across three age groups (25, 45, 65) and three BMI variations of -10%, baseline and +10%, yielding 4320 paired samples. To the best of our knowledge, this is the only X-ray-face dataset with this magnitude. Extensive experiments showed that the proposed method outperforms recent existing approaches in both generated image quality and retrieval task. Finally, to evaluate the performance of our proposed method, we have evaluated the quality of the generated image using FID, IS, SSIM, LPIPS, PSNR and ArcFace score. Additionally, retrieval performance is evaluated using recall@k, mAP@k and MRR@k. Obtained experimental results demonstrate that the proposed method can be used as an alternate tool in providing aid in forensic investigations.

Measuring the angle between bone structures is a routine task in medical image analysis and provides a key quantitative parameter for diagnosis and treatment planning. Automated methods can reduce time and cost while improving reproducibility. In this work, we address automatic bone pose estimation using a learning-based point candidate proposal followed by a line model to extract axis parameters. Since conventional line models such as least squares are sensitive to outliers, we incorporate false-positive reduction strategies and robust fitting techniques, such as RANSAC and Hough transforms, to improve robustness. We evaluate our method on three clinically relevant paediatric angle estimation tasks: fracture fragment assessment in radiographs and ultrasound and developmental dysplasia of the hip evaluation in ultrasound using the Graf method. Our approach achieves mean errors of $4.1^\circ$, $5.4^\circ$, and $5.51^\circ$, respectively, not only remaining within the expected clinical observer variability, but also significantly outperforming landmark-based methods. Our code and annotations for fracture angle assessment in radiographs are publicly available on GitHub.

We identify and resolve a previously unreported failure mode in TensoRF when applied to X-ray attenuation fields: the default density shift of -10, originally introduced for RGB scene reconstruction, suppresses density gradients and prevents sparse-view medical reconstruction regardless of learning rate or regularization strategy. Setting the density shift to zero restores gradient flow and enables stable volumetric reconstruction of pulmonary nodules from only three orthogonal X-ray projections. Building on this, we propose AReT, an anatomy-regularized tensorial radiance field framework for lung nodule reconstruction using coronal, sagittal, and axial projections from the LIDC-IDRI dataset (19 patients, radiologist-annotated nodules). Unlike existing NeRF approaches requiring dense multi-view acquisition, AReT is designed for sparse-view thoracic imaging and incorporates chest-anatomy-aware regularization combining L1 sparsity and total variation smoothness. A systematic comparison across 11 reconstruction strategies shows anatomy-aware regularization consistently outperforms generative-prior-guided approaches. Evaluated against radiologist consensus segmentations, AReT achieves Pearson r=0.983 (p<0.0001) for clinically actionable nodules >=10 mm (n=14), median absolute volumetric error of 11.4%, near-zero systematic bias of -77.3 mm^3, and 8.4x improvement over spherical volume approximation.

Reliable identification of fracture origins in alumina matrix composite hip and knee implants is critical for quality assurance and patient safety, yet current fractographic workflows are time-consuming, partly subjective, and reliant on high-magnification scanning electron microscopy (SEM). We present an interpretable vision-transformer (ViT) workflow for automated classification of fracture causes in an alumina matrix composite (BIOLOX delta, CeramTec GmbH) widely used in total joint replacements. A dataset of 8,493 SEM images (50x-10,000x) was curated from five years of in-production burst and proof tests and annotated into three defect categories defined along the manufacturing chain: green body, hard machining, and material defects. Under severe class imbalance, the fine-tuned ViT reached an accuracy of 0.907 and a macro-F1 of 0.888 in stratified five-fold cross-validation, with a two-stage perceptual-hash/SSIM leakage audit confirming negligible specimen overlap. Notably, performance at low magnification (50x) was comparable to that at high magnification (1k-10kx), indicating that macro-scale features - mirror geometry and hackle line fields - already encode sufficient diagnostic signal. Grad-CAM attributions consistently localised on canonical fractographic cues (mirrors, hackles, pores, machining marks), aligning with established fractographic criteria. Together, these results position interpretable ViTs as a complementary tool for ceramic-implant quality assurance, enabling low-magnification pre-screening and reducing reliance on time-intensive high-magnification inspection.

Vision foundation models pretrained on web-scale data have recently shown strong transfer capabilities on many downstream tasks, but their effectiveness for industrial visual inspection remains unclear. Industrial data differ substantially from web-data and often require fine-grained dense prediction, raising the question of whether modern self-supervised pretraining can improve over the conventional transfer-learning paradigm based on supervised ImageNet initialization. In this work, we compare ConvNeXt backbones pretrained with supervised ImageNet classification or DINOv3 distillation, and relate them to the conventional ResNet-50 baseline. We evaluate semantic segmentation, instance segmentation, and object detection across four downstream datasets spanning RGB surface-defect inspection and X-ray defect detection. We further study both frozen and fully finetuned adaptation regimes. Our results show that DINOv3 offers no clear advantage in frozen transfer, but provides a stronger initialization after full finetuning on RGB tasks, yielding faster convergence and better final performance. Under X-ray modality shift, however, supervised ImageNet pretraining remains more effective in both frozen and finetuned settings. Overall, our findings suggest that modern vision foundation models are promising for supervised RGB industrial inspection, but their transferability is strongly conditioned by downstream adaptation and target modality.

Accurate segmentation of maxillary sinus in panoramic X-ray images is essential for dental diagnosis and surgical planning; however, this task remains relatively underexplored in dental imaging research. Structural overlap, ambiguous anatomical boundaries inherent to two-dimensional panoramic projections, and the limited availability of large scale clinical datasets with reliable pixel-level annotations make the development and evaluation of segmentation models challenging. To address these challenges, we propose a semi-supervised segmentation framework that effectively leverages both labeled and unlabeled panoramic radiographs, where knowledge distillation is utilized to train a student model with reliable structural information distilled from a teacher model. Specifically, we introduce a weighted knowledge distillation loss to suppress unreliable distillation signals caused by structural discrepancies between teacher and student predictions. To further enhance the quality of pseudo labels generated by the teacher network, we introduce SinusCycle-GAN which is a refinement network based on unpaired image-to-image translation. This refinement process improves the precision of boundaries and reduces noise propagation when learning from unlabeled data during semi-supervised training. To evaluate the proposed method, we collected clinical panoramic X-ray images from 2,511 patients, and experimental results demonstrate that the proposed method outperforms state-of-the-art segmentation models, achieving the Dice score of 96.35% while reducing boundary error. The results indicate that the proposed semi-supervised framework provides robust and anatomically consistent segmentation performance under limited labeled data conditions, highlighting its potential for broader dental image analysis applications.

X-Ray Computed Tomography (XCT) is a compelling tool in experimental mechanics, capable of non-destructively extracting information pertaining to the internal morphology of materials. For materials with random heterogeneous morphology such as concrete, such information is of particular relevance since it allows for studies of morphology-related behaviour and for predictive modelling. Nevertheless, XCT images require semantic segmentation for practical usage. Here, concrete poses a unique challenge due to the similar X-ray attenuation coefficients of aggregates and mortar, which result in low contrast between the two phases in the ensuing XCT images. As such, purely intensity-dependent semantic segmentation tools remain unfeasible. While vision transformers (ViTs) and convolutional neural networks (CNNs) are proven techniques for semantic segmentation in such challenging cases, they typically require labelled training data, which is often unavailable for concrete or resource-intensive to obtain, thereby limiting their relevance. To address this challenge, a self-annotation technique is presented here that leverages superpixel algorithms to identify perceptually similar local regions in an image and relates them to the global context by utilizing the receptive field of a CNN-based model. This enables the model to learn a global-local relationship in the images and facilitates the identification of semantically similar structures. When evaluated against manually annotated ground truth on out-of-distribution data, the proposed methodology consistently outperformed direct greyscale thresholding across all pertinent metrics, demonstrating improved discernibility between aggregates and mortar, and providing the most favourable balance of sensitivity and precision for aggregate-phase identification.

We present Xray-Visual, a unified vision model architecture for large-scale image and video understanding trained on industry-scale social media data. Our model leverages over 15 billion curated image-text pairs and 10 billion video-hashtag pairs from Facebook and Instagram, employing robust data curation pipelines that incorporate balancing and noise suppression strategies to maximize semantic diversity while minimizing label noise. We introduce a three-stage training pipeline that combines self-supervised MAE, semi-supervised hashtag classification, and CLIP-style contrastive learning to jointly optimize image and video modalities. Our architecture builds on a Vision Transformer backbone enhanced with efficient token reorganization (EViT) for improved computational efficiency. Extensive experiments demonstrate that Xray-Visual achieves state-of-the-art performance across diverse benchmarks, including ImageNet for image classification, Kinetics and HMDB51 for video understanding, and MSCOCO for cross-modal retrieval. The model exhibits strong robustness to domain shift and adversarial perturbations. We further demonstrate that integrating large language models as text encoders (LLM2CLIP) significantly enhances retrieval performance and generalization capabilities, particularly in real-world environments. Xray-Visual establishes new benchmarks for scalable, multimodal vision models, while maintaining superior accuracy and computational efficiency.

X-ray micro-computed tomography (micro-CT) provides non-destructive three-dimensional (3D) imaging of porous material microstructures. In situ experiments, including mechanical loading and reactive transport, increasingly require dynamic four-dimensional (4D) imaging with volumes repeatedly acquired during experiments. However, rapid acquisition typically requires fewer projections, shorter exposures, or reduced fields of view, producing reconstructions with noise, blur, and artifacts that obscure pores, microcracks, and interfaces. To address this challenge, this study introduces InSituRes, a physics-informed same-grid volumetric enhancement framework for fast dynamic X-ray micro-CT imaging of temporally evolving materials. InSituRes maps fast-acquisition volumes to higher-quality long-acquisition reconstructions using paired scans of the same specimens. The model integrates 3D convolutional feature extraction with slice-wise transformer attention to capture local and broader in-plane context. A learnable forward degradation model approximates rapid acquisition effects, including spatial blurring, intensity scaling differences, and signal-dependent noise. During training, reconstructed volumes should match high-quality reference scans and reproduce observed fast acquisition data after propagation through the forward model, imposing a physics-guided consistency constraint. Experiments on unseen micro-CT datasets demonstrate improved reconstruction fidelity and enhanced visibility of fine microstructural features relative to conventional interpolation and learning-based enhancement approaches. The framework supports quantitative interpretation of fast 4D X-ray micro-CT scans of evolving materials.

Computed Tomography (CT) is essential for diagnosing pediatric craniofacial abnormalities, yet poses radiation risks to developing anatomies. Reconstructing 3D CT from sparse bi-planar X-rays offers a low-dose alternative but is severely ill-posed. Existing methods employ geometry-agnostic feature lifting, naively projecting 2D features into 3D without explicit spatial modeling, causing depth ambiguity and degraded osseous boundaries. We present PSCT-Net, a geometry-aware framework with differentiable back-projection. Differentiable back-projection establishes a spatially faithful volumetric prior, alleviating depth ambiguity. An Attention-Guided Projection (AGP-3D) module then learns non-linear voxel-wise correspondences between 2D regions and 3D locations. A Bidirectional Mamba (BiM-3D) module captures long-range volumetric dependencies with linear complexity. We further curate a private institutional pediatric skull CT cohort, PedSkull-CT, comprising normal and pathological cases for internal evaluation, addressing the gap in adult-centric, trunk-focused datasets. Project page and code are available at https://dydevelop.github.io/PSCT-Net/.