Quantum Machine Learning

Classical simulation remains essential for developing and validating quantum algorithms, but its cost grows rapidly with circuit size. Tensor-network contraction can reduce this cost by exploiting circuit structure, although its efficiency depends strongly on the chosen contraction plan. On GPUs, plans with similar theoretical complexity may perform very differently because execution also depends on parallelism, reduction structure, memory traffic, and contraction geometry. We present a learning-to-rank framework for selecting efficient contraction plans before executing them. Each plan is represented by structural features derived directly from its sequence of pairwise contractions, and gradient-boosted rankers are trained from GPU measurements using listwise and pairwise objectives. We evaluate the resulting models on diverse circuit families, using separate in-distribution and circuit-family-shift test sets, and compare them with random and MinFill-based baselines. The learned rankers generally identify better plans, with the listwise model providing the strongest overall decision quality. We also study backend shift by comparing empirical plan orderings on two GPU architectures and evaluating the source-trained models on the second device without retraining. The rankings remain substantially, though not perfectly, stable across GPUs, and the models retain useful decision quality. These results support Learning to Rank as a practical way to reduce contraction-plan search, while showing that performance remains partly backend dependent.

Quantum error correction protects logical information only when every physical operation remains below the fault-tolerance threshold, a condition that must be maintained continuously rather than only at the initial calibration. In practice, however, analog control parameters inevitably drift because of environmental fluctuations. As future fault-tolerant quantum computations are expected to run for days or even months, interrupting computation for repeated recalibration becomes fundamentally impractical. A promising alternative is to integrate calibration directly into computation by repurposing syndrome measurements as a calibration signal (Sivak et al, Nature 2026), but whether such self-calibration can be achieved with provable efficiency remains an open question. Here we establish a theoretical framework for self-calibrating quantum fault tolerance. We prove that, for a broad class of control-induced errors, the detection rate defines a locally strongly convex surrogate objective for analog calibration with high probability. This geometric property enables efficient online optimization using only syndrome measurements collected during normal error correction. We prove convergence to an $\varepsilon$ detection rate within $O(1/\varepsilon^2)$ epochs for time-independent drifts and also establish guarantees for time-dependent drifts. We further show that the convergence rate is independent of the code distance for quantum low-density parity-check (LDPC) codes. Pulse-level simulations of neutral-atom arrays and large-scale circuit-level Clifford simulations confirm these theoretical predictions. Our results establish self-calibrating fault tolerance as a provably efficient paradigm in which the same syndrome measurements simultaneously protect logical information and stabilize the underlying hardware.

Exact QAOA simulation spans several computational representations whose useful regions differ sharply across graph structure, circuit depth, precision, and available memory. Choosing only a backend name hides these differences: an executable choice also fixes the representation, adapter, precision mode, and memory policy. We introduce RASP-QAOA, a per-instance selector over ten such actions. It first removes actions that cannot implement the requested QAOA semantics or execution requirements, then orders the remaining actions using instance features; actions outside learned support are handled by analytical work estimates. On a content-disjoint 60-request H200 evaluation, RASP-QAOA succeeds on all 31 requests for which at least one admissible action completes and validates. Within this set it reaches 27/31 top-1 and 31/31 top-2 selection, with 1.051 geometric-mean regret. Its failure-penalized PAR10 score is 0.0396 times that of development-selected CUAOA (95% interval: 0.0085-0.1644). A separate 30-request crossover shows that graph structure changes 16 decisions and improves the paired penalized score, while a depth-1 stump matches gradient boosting. The evidence supports resource-aware representation selection at n <= 35, p <= 5, with gains driven by representation features rather than classifier complexity.

QAOA training repeatedly queries an objective and all shared gradients, making exact evaluation a feasibility bottleneck even when QUBO terms have bounded causal cones. Building on established causal-cone restriction and adjoint differentiation, LC-Implicit-QAOA profiles cone structure and induced-edge counts before local-amplitude and named-workspace allocation, then jointly selects equal-size microbatches and checkpoint schedules under a named active-evaluator workspace budget. "Implicit" means omitting both global state and global cost table, not implicit differentiation; infeasible requests are rejected before those allocations. An independently implemented complex128/float64 dense adjoint agrees with LC over 1,800 graph-angle comparisons, with a worst relative gradient error of 1.56 x 10^-13. LC completes all 104 target requests in a p=2 bounded-cone grid; under a prespecified n <= 24 validation cap, the matched state-plus-cost reference is executed for 28 requests and deliberately not run on 76. Across 80 budgeted requests, measured allocated evaluator memory stays within budget, reaching at most 0.797 of it. On 3-regular n=512, p=2, the adjoint reaches the same finite-budget endpoint in 101 objective-equivalent calls and 189 s, versus 909 calls and 1,565 s for central differences. LC targets fixed-depth one- and two-local diagonal QUBO costs with a transverse-field mixer; it provides neither global states, sampling, nor a hardware-independent fastest-backend rule.

Circuit cutting lets a large quantum neural network (QNN) run as independent subcircuits on small devices, but rebuilding its outputs by reconstruction carries a classical sampling overhead exponential in the number of cuts - the dominant runtime cost in prior work. We ask whether, for machine-learning tasks, this step is necessary, and replace it with late fusion: each subcircuit is trained and measured independently, and a small classical head combines their outputs - a linear-cost, decision-level combination borrowed from multimodal learning. To characterize the trade-off we introduce a quantumness dial $Q$, a tunable reconstruction budget interpolating from pure fusion to full reconstruction, and a cut-entanglement diagnostic that indicates how much reconstruction a task needs (Spearman $ρ=0.59$ over $104$ runs). Across synthetic and standard datasets, independently trained late fusion matches full reconstruction accuracy within $0.04$ at every point of the controlled sweep and on every classical benchmark, at exponentially lower cost; it is also markedly more robust to shot and device noise. Controlled entangled-data experiments locate the boundary where fusion must fail. We do not claim advantage over classical machine learning - consistent with recent benchmarking, quantum offers no accuracy edge on these datasets. Late fusion is thus an efficient, noise-robust, self-characterizing alternative to reconstruction for circuit-cutting QML.

World models learn latent states that summarize interaction histories, evolve over time, and support prediction, simulation, or planning. Most existing world models represent these states using classical vectors, probability distributions, recurrent hidden states, or transformer activations. In this paper, we introduce Quantum-Structured World Models (QSWMs), a quantum-inspired framework for predictive world modeling with structured latent states, latent transition operators, and measurement-inspired decoding maps. We study whether mathematical structures inspired by quantum theory, such as complex-valued representations and density-matrix-like latents, provide useful inductive biases for world modeling. We establish three foundational properties: classical inclusion, predictive sufficiency, and structured compactness. We then instantiate complex-valued and density-matrix-like QSWM variants and evaluate them on elementary cellular automata against strong classical baselines. Results show promising local predictive potential for complex-valued QSWMs, while also revealing limitations in long-horizon rollout, density-matrix variants

Near-term quantum hardware limits circuit depth and often imposes geometrically local connectivity for quantum generative models, restricting the output distributions accessible to shallow unitary Born models. Introducing stochasticity into a unitary quantum Born model can improve the empirical generative performance of the resulting channel model and, for a restricted small-scale architecture, has been proven to represent a strictly larger family of distributions than its unitary counterpart. However, whether such randomness provides a provable separation at fixed shallow depth for arbitrarily large systems has remained open. Here, we show that shared classical randomness, a comparatively weak resource from entanglement theory, is sufficient to establish such a strict scalable representational separation over the corresponding shallow unitary Born model. More specifically, we augment bounded-connectivity shallow unitary circuits, followed by computational-basis measurements, with spatially separated local Pauli operations, whose joint application is controlled by a single classically sampled random bit. The resulting shallow-depth channel model generates long-range correlations in the classical output distribution that no purely unitary shallow-depth model with bounded connectivity can reproduce. For one-dimensional nearest-neighbour architectures, reproducing such distributions with a purely unitary model can require depth $Ω(N)$ in the worst case. We further show that measurement-based quantum computation (MBQC) provides a natural implementation of the required shared classical randomness through suitable adaptation of the random measurement outcomes. Numerical experiments on MBQC-based generative models support the analytical results.

One-bit post-training quantization represents each weight using only its sign, requiring all deployment contexts to share the same binary weight matrix even when their activation statistics favor different sign patterns. We study this shared-sign constraint and introduce Quantum Random Access Quantization (QRAQ). This framework encodes context-dependent signs in a quantum random-access code and retrieves them via context-matched Pauli measurements. Under an explicit fresh-copy logical readout model, QRAQ produces an unbiased, context-specific binary surrogate with a tractable shot-noise penalty. We prove a row-wise separation from shared-sign one-bit PTQ with signed per-row scales. When the optimal context-wise signs are incompatible, QRAQ achieves a strictly lower ideal reconstruction risk. We also derive finite-shot and calibrated-noise conditions under which this separation is retained. Fixed-readout quantum schemes are classically simulable, so the relevant resource in this model is measurement incompatibility rather than quantization alone. Finally, we characterize the role of scale granularity, provide finite-sample certificates, and evaluate the predicted ideal, finite-shot, noisy, and multi-context regimes in simulator experiments.

We propose a method to optimize the correlation among convolutional neural network (CNN) features that are used as inputs to quantum neural network (QNN) to enhance image classification accuracy. Unlike prior approaches that employ orthogonal decomposition as preprocessing, we intentionally introduce correlated features that are more physically compatible with QNN. This design leverages the QNN's inherent ability to exploit quantum entanglement for representing correlated states-an advantage unavailable to classical neural networks. We hypothesize that aligning feature correlations with the entanglement structure of QNN improves binary classification performance. Based on a mathematical derivation of QNN outputs, Monte Carlo simulations indicate that an average correlation between features of 0.5 yields optimal classification accuracy. To validate this finding, we evaluate a quantum-classical hybrid model on three tasks: CIFAR-10 (automobile vs. truck), Fashion-MNIST (shirt vs. coat), and radar micro-Doppler signatures (robotic dogs vs. non-robots). To regulate feature correlations, we introduce a correlation-regularization term on the outputs of the CNN, driving the off-diagonal entries of the feature correlation matrix toward a target constant. Across all datasets, inducing intermediate correlation consistently improved accuracy compared to low, high, or unregulated correlations, while also reducing classification accuracy variance. These results demonstrate that imposing moderate feature correlations-without modifying the quantum circuit-enhances classification accuracy and stability by aligning feature statistics with the QNN's entanglement structure. This study highlights the potential of QNN to surpass the performance of classical classifiers as more qubits become available.

The dynamical Lie algebraic (DLA) theory of variational quantum algorithms (VQAs) predicts commonplace exponentially vanishing loss and gradient variances for sufficiently deep parametrized circuits. In this work, we show that these predictions fail dramatically in the shallow-circuit (and particularly constant-depth) regime for the Quantum Approximate Optimization Algorithm (QAOA) applied to the maximum independent set (MIS) problem. In a large-scale numerical study across $\sim$23,000 problem instances, we find that barren plateaus are rare, while landscapes whose variances polynomially increase with system size---which we term "cragged terrains"---are common across graph families. This aggregate polynomial growth persists both for generic, low-symmetry random graphs and for highly symmetric vertex-transitive graphs, indicating that DLA-based variance predictions do not describe landscape scaling in this regime. As a stopgap alternative to the theory, we train empirical hardness models to predict instance-wise hardness metrics for QAOA-MIS. While these models generalize poorly, they nonetheless recover the correct landscape scaling class (barren plateau vs. cragged terrain) with high fidelity. Taken together, our results identify shallow QAOA for MIS as a prototypical setting in which asymptotic, unitary-design-centric predictions may be fundamentally insufficient to describe shallow variational quantum algorithms more broadly, emphasizing the need for more empirically-informed models of VQA loss landscapes.

Modern large language models - transformers and diffusion language models - are built around two canonical algorithmic tasks: prediction and generation. We prove unconditional separations between low-depth quantum computation and the corresponding bounded-resource classical language-model architectures in both regimes. Concretely, we exhibit the following: 1. Distributional separation. We give a distribution that is sampleable by $\textsf{QNC}^0$ circuits (i.e., a family of constant-depth quantum circuits consisting of bounded fan-in gates) that no constant-round diffusion language model ($\textsf{DLM}$) with shallow scheduling and denoising can sample within constant distance, even when allowed sublinear chain-of-thought and output-token revision/remasking events, the very features modern $\textsf{DLM}$s rely on. 2. Functional separation. We exhibit a function computable in $\land \circ \textsf{QNC}^0[\log\log n]$ (i.e., a family of O$(\log\log n)$-depth $\textsf{QNC}^0$ circuits, where $n$ is the input length, followed by a single classical $\mathsf{AND}$ gate) such that any constant-depth decoder-only transformer computing the function must be large: it would have to have width $n^{Ω(1)}$. Together, our work initiates the study of quantum advantage in the era of large language models.

The performance of Support Vector Machines (SVMs) critically depends on the kernel function choice, which enables implicit mapping of data into high-dimensional feature spaces. While classical kernels like Radial Basis Function (RBF) remain popular, orthogonal polynomial kernels offer mathematically interpretable alternatives that can incorporate structured prior knowledge. This work extends the orthogonal polynomial kernel paradigm by introducing a novel family based on discrete $q$-Hermite I polynomials, a class of $q$-orthogonal polynomials that generalize classical Hermite polynomials through a deformation parameter $q$. We formally define the q-Hermite kernel and establish its validity under Mercer's theorem. The kernel's inherent boundedness properties naturally prevent annihilation and explosion effects without requiring explicit scaling mechanisms. Extensive experiments across 20 benchmark datasets demonstrate that the proposed kernel achieves competitive performance compared to both classical kernels and other orthogonal polynomial kernels, while offering advantages in numerical stability and computational simplicity. Our results confirm that $q$-orthogonal polynomials constitute a promising direction for kernel design, bridging mathematical elegance with practical machine learning applications, that provides conceptual and algorithmic resources that may be further extended to emerging quantum computing paradigms. To facilitate full reproducibility, we provide the complete implementation and experimental pipeline in an open-access GitHub repository at https://github.com/Kokechacho/SVMs-QSVMs.

The minimum change principle provides an information-theoretic characterization of the Bayes reversal channel in classical probability theory and has recently been proposed as a framework for extending Bayes' rule to quantum information theory. Using quantum relative entropy, we investigate a minimum change principle for the setting of quantum statistical inference. Specifically, we consider a forward process based on a classical-to-quantum preparation channel and a reverse process based on a quantum-to-classical measurement channel. We establish a closed-form characterization of measurements that are optimal for this principle, and this optimal measurement can be found via a dual formulation involving a single unconstrained Hermitian variable. This perspective allows us to recover some notable measurements within the same framework, including pretty good measurements and Fermi-Dirac thermal measurements, and we use it to discover a novel family that we call softmin thermal measurements. We further show that softmin thermal measurements arise as optimal solutions to entropy-regularized semidefinite optimization problems, demonstrating that they play a role for measurements analogous to that of thermal states in statistical mechanics. Finally, we prove an additivity property for the relative-entropy minimum change principle and investigate the performance of Fermi-Dirac thermal measurements for quantum hypothesis testing.

Conventional BB84 Quantum Key Distribution (QKD) systems rely on a fixed 11% Quantum Bit Error Rate (QBER) threshold to detect eavesdropping. However, stealthy attacks can remain below this threshold while still compromising channel security. This paper proposes a temporal QBER based machine learning framework for detecting and classifying eavesdropping attacks in BB84 QKD systems. Rather than relying on average session level QBER, the framework extracts 63 physics-informed temporal features capturing burst behavior, temporal instability, basis dependent asymmetry, and QBER loss interactions. Random Forest, XGBoost, and Support Vector Machine with a Radial Basis Function kernel (SVM-RBF) classifiers are evaluated on seven eavesdropping attacks and a normal channel scenario under noisy and lossy conditions. Averaged over ten independent runs, XGBoost achieves the best performance with 88.01% (0.47%) accuracy and a macro F1 score of 0.8803, while SVM-RBF performs comparably, confirming the robustness of the proposed features. Evaluated as a binary attack-versus-normal detector for comparison with conventional monitoring, a fixed 11% QBER threshold achieves only 25.82% accuracy with a False Negative Rate (FNR) of 0.8477, whereas the proposed framework reduces the FNR to 0.0198, substantially improving detection of stealthy attacks that evade threshold-based monitoring. SHapley Additive exPlanations based (SHAP) explainability shows that physics-informed temporal and channel derived features are highly discriminative for identifying eavesdropping strategies. These results demonstrate that temporal QBER driven machine learning provides an accurate, explainable, and practical framework for multi attack security monitoring in BB84 QKD systems.

Reinforcement learning is a subfield of machine learning that studies how an agent interacts with an environment in order to extract as large a reward as possible. A standard approach to study such interaction is through Markov Decision Processes (MDPs) and the task of choosing an optimal policy --- a function that tells the agent which action to take. In this work, we study two types of MDPs --- finite-horizon and infinite-horizon discounted --- and propose new quantum algorithms for computing approximate optimal policies. Our quantum algorithms are based on a new combination of standard value iteration and quantum subroutines like quantum mean estimation and quantum maximum finding, overall enhanced with techniques from sample-optimal classical algorithms. Our resulting query complexities improve upon previous works, thus approaching already established quantum lower bounds.

Classical neural networks frequently produce overconfident predictions on ambiguous or out-of-distribution (OOD) data, a liability that grows with each AI system deployed in safety-critical real-world scenarios. Bayesian neural networks (BNNs) provide a principled framework for uncertainty-aware prediction by replacing deterministic parameters with probability distributions, but repeated sampling increases latency, memory traffic, and energy consumption. Photonic probabilistic computing offers a promising alternative by exploiting intrinsic optical stochasticity for fast and parallel sampling. However, photonic BNNs are not ideal samplers: analog constraints on quantization, programming error, dynamic range, and representable mean and variance restrict the variational families that can be implemented in hardware. In this work, we study which hardware-imposed constraints limit scalable photonic BNN inference, how these constraints can be represented, and which ranges can be tolerated by photonic BNNs beyond small proof-of-concept networks. We formulate photonic BNN inference as constrained stochastic variational inference and perform a systematic ablation study over stochasticity location, stochasticity modality, quantization, programming error, and mean/variance bounds. From these results, we derive concrete co-design guidelines that distinguish hardware constraints that can be compensated by training from those requiring hardware or architecture intervention. We validate these guidelines under coupled, hardware-realistic constraints on Dirty-MNIST, CIFAR-10, and CINIC-10, using Fashion-MNIST and SVHN as OOD benchmarks, showing that hardware-aware training recovers predictive performance and uncertainty quality whenever the required variational family remains representable, whereas violations of representational limits require targeted hardware modifications.

Bosonic quantum systems provide a hardware-efficient platform for quantum information processing but remain challenging to characterise due to their large Hilbert space and the high measurement cost of state tomography. Existing approaches estimate the fidelity with respect to a single target state, making them unsuitable for applications in which physically equivalent states differ by phase space translations, rotations, or other transformations. Here, we introduce an adaptive reconstruction technique that estimates the fidelity with respect to a family of bosonic states while reconstructing the underlying Wigner function from a small number of measurements. The method combines a physics-informed parametric model with Bayesian inference, bootstrap, and active learning to iteratively select the most informative phase space sampling points. We implement the approach on a circuit quantum electrodynamics platform and benchmark it on Schrödinger cat states with amplitudes $α\in[1,3]$. The reconstruction yields reproducible fidelity estimates within a few minutes, remains robust to substantial displacements and rotations in phase space despite using a mismatched prior, and is sensitive to subtle state imperfections. We further compare the adaptive strategy with existing Wigner function sampling protocols experimentally, demonstrating the advantage of adaptive sampling for measurement-efficient fidelity estimation with respect to a family of cat states. Finally, we incorporate the reconstructed fidelity into the figure of merit used in a proof-of-principle closed-loop quantum optimal control experiment, demonstrating the applicability of the method to autonomous optimisation of bosonic quantum states.

Normally the statistical mechanics of learning treats constraints on weight distributions as restrictions that shrink the space of possible solutions. Therefore, it reduces model capacity. In this paper we would like to take a contrary approach, which, however, is based on the earlier work on distribution-constrained perceptrons. Rather than treating a prescribed weight distribution as a mere restriction, we propose that it defines the intrinsic geometry upon which learning naturally unfolds. We formulate both deep neural networks and variational quantum circuits as gradient flows on a product of Wasserstein manifolds -- one classical Wasserstein space for each layer and one quantum Wasserstein space for the circuit parameters. Within this geometry, the capacity reduction, which was previously associated with distributional constraints, appears as the metric structure of the constraint manifold itself. We develop a hierarchical mean-field description for deep networks, extend the framework to the quantum setting using the quantum Wasserstein distance of order 1, and introduce two such practical algorithms, Hierarchical DisCo-SGD and Quantum DisCo, that follow approximate geodesics on the manifold of the product itself. Experiments on teacher-student problems, standard image classification tasks, and small variational quantum classifiers show that respecting these distributional geometries improves generalization, stabilizes training, and reduces the severity of barren plateaus compared with unconstrained and purely norm-based baselines. This approach firstly reframes structural constraints as geometric priors and suggests a route for incorporating biological, spectral, or hardware-derived distributional information into both learning systems, viz., classical and quantum learning.

Artificial intelligence has been transformed by deep neural networks, yet the search for new learning architectures continues. Quantum machine learning offers one such direction, and hybrid quantum neural networks, which combine classical neural-network components with quantum information processing units, have emerged as a practical framework for near-term quantum technologies. However, the rapid development of the field across diverse architectures, benchmarks and hardware assumptions makes it difficult to assess the utility of various proposals, identify where genuine advantages may arise, and determine how practitioners can use these models. While recent benchmarks caution that such gains have not yet been demonstrated at scale, theoretical work has identified tasks on which quantum models hold provable advantages, and hybrid approaches have delivered promising results on practical problems using deliberately compact quantum components and substantially fewer trainable parameters. Here, we review hybrid quantum neural networks for the machine-learning and quantum-machine-learning communities. We summarize their main theoretical and methodological foundations, survey some of the most promising architectures developed so far, and examine their implementation challenges and reported performance. By consolidating these perspectives, this review provides a structured view of the state of the field and helps identify promising paths for future research and application-driven development.

Physics-informed neural networks (PINNs) have emerged as a versatile approach for solving nonlinear partial differential equations (PDEs), yet achieving high accuracy efficiently using these techniques remains challenging for high-dimensional or multiscale systems. Here, we present a hybrid quantum-classical framework that enhances Quantum PINNs (QPINNs) through adaptive collocation point sampling and loss-aware attention mechanisms. By dynamically prioritizing points in regions with large PDE residuals or steep solution gradients, our method mitigates the spectral bias inherent in conventional PINNs. Current Quantum Physics-Informed Neural Networks are commonly assumed to be limited by the expressive power of quantum circuits. In our work, we observed that, across diverse differential equations, optimization - not only expressivity - can be an important bottleneck. Furthermore, a trainable loss-weighting scheme balances contributions from physics residuals, boundary conditions, and data fidelity during training. Integrating these strategies with quantum computing techniques (including variational quantum circuits and quantum gradient estimation) can yield at least a 60% improvement in solution accuracy under specific regimes for benchmark fluid flows and reaction-diffusion systems. Finally, we argue that merely increasing model expressivity is insufficient for resolving complex PDEs via QPINNs, as they remain constrained by the structural optimization limitations of classical PINNs. This framework provides a scalable pathway for quantum-enhanced scientific machine learning, bridging physics-based modeling with emerging quantum computational capabilities.

Reinforcement-learning-based quantum architecture search (RL-QAS) repeatedly optimizes a variational quantum eigensolver (VQE) after extending a circuit, although circuit construction and action legality are deterministic and known. We introduce DreamQAS, a model-based RL framework that preserves these exact circuit dynamics and learns only the expensive post-VQE feedback. A recurrent randomized-prior ensemble predicts an oracle-free score relative to an empirical energy frontier and supports multi-step imagined policy learning over explicit legal circuits. Ranking-based activation, uncertainty-aware pessimism and truncation, and selective real-VQE verification form a reliability-controlled learning loop. Under a common 15,000-episode budget and frozen evaluation for the RL methods, DreamQAS has the lowest mean frozen-policy energy error on four of five molecular tasks and the second-lowest on one. At fine-error targets reached by all seeds of both methods, it uses 1.6x to 2.0x fewer real VQE calls on four tasks and 10.6x fewer on BeH2-8q. Counterfactual action-ranking utility increases across all five tasks, with a mean increase of 0.346 and a 95 percent confidence interval of [0.185, 0.507], while direct greedy and beam use of the same model does not recover the gains of imagined policy learning. Ensemble disagreement also improves risk-coverage over random rejection on all three probed tasks. These results establish a world-model design for QAS whose value lies in decision-useful feedback rather than exact energy prediction.

Quantum software engineering is an emerging research field focusing on efficiently embedding the quantum programming paradigm into existing software ecosystems. A key aspect of this field is the realization of quantum algorithms using gate-based programming and the subsequent low-level optimization of the resulting quantum circuits, a process that is commonly performed by so-called transpilation pipelines. One significant challenge in these pipelines is determining which optimizations to apply to a given circuit. This decision is usually based on fixed default configurations that are uniformly applied to all circuits, frequently resulting in missed opportunities for more aggressive circuit optimization. In this work, we tackle this challenge by applying autotuning with supervised machine learning to develop an automated method for selection of transpiler passes. To train our machine-learning models, we employ feature-model based sampling to generate a representative dataset that examines how different combinations of Qiskit transpiler passes perform across thousands of circuits drawn from the state-of-the-art benchmarking suite MQT Bench. Using these data, we build a predictive model extension for the Qiskit transpilation pipeline that uses a machine learning model to automatically select combinations of transpiler passes aiming to achieve a maximum reduction in two-qubit gates. Our empirical evaluation shows that the combinations selected by our model are never outperformed by Qiskit's optimization levels, achieve on average an additional 19.1$\%$ - 32.4$\%$ reduction in two-qubit gates, and for some circuits finds reductions of up to $95.8\%$ in cases where Qiskit achieves no reduction at all.

Recent work suggests that relational database management systems (RDBMSs) can execute quantum circuit simulation by compiling the simulation into SQL workloads (primarily join-and-aggregate tensor contractions). While early results are promising, they largely focus on a narrow set of highly structured circuits and offer limited support for systematic database research, such as query optimization, physical design, and engine-level evaluation across a broad range of circuits. We present InferQ, a database-oriented benchmark for quantum circuit simulation. InferQ generates general, compositional circuits by assembling subcircuits from a set of circuit templates, emits each simulation task as an RDBMS-ready SQL workload, and extracts circuit and query features (static, graph, SQL, and dynamic) for workload characterization. InferQ also releases a large dataset of 202,975 circuits online, with a web-based viewer to support searching, filtering, and downloading circuits and feature records. In experiments across RDBMS engines (PostgreSQL, SQLite, DuckDB, and Umbra) and the widely used Qiskit Aer simulator, we find that RDBMSs achieve better peak memory usage than Qiskit Aer on more than 50% of the circuits generated by InferQ. Moreover, using InferQ features, lightweight machine learning models (linear and tree-based models) can accurately predict when SQL execution is preferable (with accuracy up to 95.6% for runtime and 97.4% for memory), enabling data-centric simulator selection and opening the door to principled optimization of SQL-based quantum circuit simulation.

Molecular optimization is commonly performed under a limited oracle budget, which makes deciding what to evaluate as important as deciding what to generate. We introduce short-term graph memory, a plug-in module that preserves the generator architecture and native update rule while learning from previously evaluated molecules to prioritize subsequent oracle queries. The module maintains an online graph neural surrogate that pre-screens each round's candidate pool, so the fixed oracle budget is spent on molecules with higher predicted utility. Applied to a fragment-based generator on a standard molecular optimization benchmark, it improves the mean top-10 score at no extra oracle cost and never falls behind the base on any oracle; the gain extends to all four generators we tested at a tight budget of one thousand calls. We then analyze how surrogate-guided selection interacts with the exploration and exploitation behavior of different generators. Its benefit at larger budgets is consistent with two properties of the backbone: how broadly it searches, and how effectively its native search already exploits oracle feedback. We provide a simple way to spend a fixed oracle budget more selectively, and evidence on which generators benefit from it.

Fault-tolerant quantum computing (FTQC) relies on quantum error correction to suppress physical errors and preserve logical information at scale. In practice, however, performance is constrained not only by physical noise but also by the latency of classical decoders processing rapidly generated syndrome data. This challenge is exacerbated by hardware noise that is strong, heterogeneous, and nonstationary, as well as by the simulation-to-hardware distribution shift that can substantially degrade fixed neural decoders. We present QAdapt, a noise-adaptive neural pre-decoding framework for surface-code quantum error correction. QAdapt captures local spatiotemporal correlations in syndrome data, sequentially adapts to evolving noise conditions while mitigating catastrophic forgetting, and forwards the residual syndrome to a conventional global decoder. Across 110 synthetic out-of-distribution noise configurations for rotated surface-code memory circuits, QAdapt consistently reduces the logical error rate relative to the neural pre-decoding baseline. On Google's Willow benchmark data, without target-domain fine-tuning, it achieves reductions of up to 5.79 percent in logical error rate and 9.32 percent in backend decoding latency on the residual syndrome. These results demonstrate that QAdapt provides a practical and decoder-compatible approach to improving the robustness and backend decoding efficiency of quantum error correction under evolving hardware noise.

Sequence models must decide what to write into memory and what to retain. In quantum and quantum-inspired sequence learning, nonlinear recurrent updates often require repeated circuit evaluations and sequential backpropagation through time, making long contexts costly. Gated fast-weight programmers (FWPs) based on quantum-inspired Kolmogorov-Arnold networks (QKANs) alleviate this bottleneck by storing context in time-varying fast parameters. However, their scalar gate applies one retention-write balance to every fast-state coordinate, forcing all parameters to share a memory timescale. We introduce Self-Modulating QKAN-based FWPs, which replace this broadcast gate with low-rank-generated element-wise modulation of the new-proposal branch, a bounded old-state branch, or both. We further propose Complementary Matrix Gating (CMG), which uses one sigmoid matrix gate to retain the old state and its complement to write the new proposal. CMG provides coordinate-wise memory control while preserving the bounded convex update and affine prefix-scan structure of scalar gating, at the modulation-head cost of a single-branch rule. We compare four self-modulating rules with scalar gating across four FWP architectures combining classical and QKAN-based slow and fast programmers. Across seven single-step forecasting benchmarks and five sequence lengths, CMG gives the most consistent improvements for architectures whose fast programmer incorporates a QKAN-based module. In direct multi-step forecasting of Jaynes-Cummings and transmon-resonator dynamics simulated with CUDA-Q Dynamics, CMG models maintain mean-squared errors on the order of 0.001 or lower across forecasting horizons of 4, 8, and 16 steps, while improving on their scalar-gated counterparts by at least 91.2%. These results establish coordinate-wise complementary modulation as a stable and effective update for QKAN-based FWPs.

Recent advances in quantum computing are opening new possibilities for Earth Observation (EO) data analysis. Quantum machine learning (QML) approaches offer novel ways to process information by exploiting quantum phenomena such as superposition and entanglement. These capabilities have motivated the exploration of whether quantum-enhanced models can address long-standing challenges in satellite remote sensing, where complex spectral and spatial signals often require sophisticated feature extraction. Among various fields of application, EO data allow the global monitoring of volcanic clouds and are crucial for aviation safety, hazard assessment, real-time eruption response, and evaluation of volcanic impacts on climate. Yet accurate detection of volcanic clouds remains difficult due to their similarity with meteorological clouds, the variability of eruption signatures, and the coarse spectral sampling of geostationary sensors. In this work, the potential of hybrid quantum convolutional neural networks (QCNNs) for the classification of satellite images containing volcanic clouds was investigated. These architectures integrate quantum computational layers into a classical convolutional framework. Two QCNN variants (with 2 and 4 qubits) have been considered to evaluate their ability to classify a dataset of SEVIRI images, including scenes with volcanic clouds (composed of ash, $SO_2$, or mixed components) as well as non-volcanic backgrounds. Finally, the performance of the hybrid QCNN models was compared with that of purely classical architectures.

As Earth Observation (EO) enters the Big Data era, the exponential volume of daily satellite imagery poses significant computational and storage challenges for classical Deep Learning (DL) models. Moreover, current approaches often struggle to generalize across heterogeneous sensors and volcanic environments while requiring large labeled datasets and substantial computational resources. These limitations are particularly critical for emerging On-Board Processing (OBP) applications, where memory, computational power, and annotated data are inherently limited. This work proposes a Hybrid Quantum AlexNet architecture for cross-sensor recognition of volcanic thermal activity at the global scale. The proposed model combines a classical convolutional backbone for high-level spatial features extraction with a parameterized quantum circuit (PQC) acting as a variational layer. By embedding high-level image representations into a high-dimensional Hilbert space, the quantum layer learns task-specific representations that enhance feature discrimination. Experimental results demonstrate that the proposed hybrid quantum model learns more discriminative feature representations, leading to improved cross-sensor transferability and robustness across heterogeneous volcanic environments using fewer trainable parameters and reduced training data than its classical counterpart.

Variational quantum algorithms often encounter barren plateaus, where cost gradients decay rapidly with increasing circuit depth, undermining the trainability of parameterized quantum circuits. This paper evaluates AdaInit (Adaptive Initialization), proposed by Zhuang and Cunningham, which uses large language models to propose initial parameters for quantum neural networks. We study a simplified single-query AdaInit variant paired with GPU-accelerated simulation in NVIDIA CUDA-Q and apply it to binary classification on the DMR-IR mammography dataset. AdaInit delivers 14.6 times higher gradient variance at initialization than random initialization (0.0095 vs. 0.0006), producing 160 times faster convergence (1.1s vs. 176 s) while maintaining the same classification accuracy of 61.4 percent. We provide theoretical analysis grounded in the geometry of parameterized circuit landscapes and show empirically that LLM-guided initialization places the optimizer in trainable regions of parameter space. Beyond performance, our results indicate that a single LLM query can yield informative parameters without iterative refinement, suggesting a low-overhead path to improved trainability. The findings validate AdaInit in a medical imaging setting and demonstrate its compatibility with GPU-accelerated quantum backends for practical speedups.

Quantum error correction (QEC) is indispensable for scalable fault-tolerant quantum computing. However, discovering QEC codes that remain effective is challenging, as logical performance depends on the interplay between code structure, hardware, syndrome extraction, and decoding, which often impose competing requirements. Here we introduce OmniQEC, an efficient AI scientist for discovering QEC codes suited to deployment on modern quantum processors. OmniQEC formulates QEC design as an iterative discovery process in which an orchestrator, implemented by advanced large language models (LLMs), coordinates code generation, code-level screening, syndrome-extraction synthesis, and decoder-based circuit evaluation. At its core, OmniQEC combines a self-evolving reasoning mechanism with a slow--fast synergistic workflow: a fast loop explores candidates using inexpensive code-level proxies, whereas a slow loop performs physically grounded circuit-level evaluation and feeds the resulting evidence back into the search. We evaluate OmniQEC across four qLDPC construction families, three LLM backends, and $14$ total-physical-qubit budgets per backend. The discovered codes show steadily improving logical-error suppression with increasing physical-qubit budgets and outperform the BB codes with $[\![72,12,6]\!]$ and $[\![144,12,12]\!]$ under complete-implementation budgets of 98 and 240 physical qubits, respectively. The discovered codes are hardware-friendly and may be of independent interest for practical QEC implementation. These findings pave the way towards LLM-assisted QEC discovery grounded in physically informed code--circuit--decoder co-design.

Quantum computers are moving from research laboratories to industrial machines accessible via the cloud and integrated into high-performance computing facilities. However, translating theoretical quantum protocols into hardware experiments remains a major bottleneck, requiring expertise across protocol design, compilation, simulation, and cloud execution. Here, we introduce an agentic workflow that automates this pipeline on neutral-atom quantum processors (here two Pasqal QPUs available on the cloud) while keeping the researcher in the loop for critical validation. In three case studies from many-body physics and optimization, the agent went from published paper or patent to a QPU campaign run overnight. In particular, human intervention was crucial to ensure scientific validity: the agent selected an inadequate observable in one experiment and constructed a plausible but incorrect hardware diagnosis in another, with both failures detected only through domain-expert review. Finally, we use a second agent to classify a corpus of 633 Rydberg-array arXiv papers and show that nearly half are implementable on present-day QPUs while identifying specific hardware upgrades needed for the rest. Together, these results demonstrate that agentic workflows provide a practical bridge between theoretical ideas and physical hardware, opening quantum experimentation to a much broader scientific community.

As quantum computing continually improves, ensuring the reliability and correctness of quantum libraries has become increasingly critical. To this end, many LLM-based fuzzing approaches towards quantum libraries have been proposed to uncover potential bugs. However, these methods still suffer from limitations such as insufficient flexibility and low efficiency, which hinder the progress of the quantum computing field. To address these challenges, we propose KQFuzz, a novel knowledge-guided fuzzer for quantum libraries. It leverages comprehensive codebase knowledge to ground LLM-based test generation, synergizing this with fitness-guided evaluation and two-level mutations to explore complex execution paths and trigger potential bugs. Firstly, KQFuzz introduces a novel prompting scheme tailored to quantum programs, which strategically incorporates knowledge of the codebase to efficiently generate high-quality quantum seed programs. Moreover, we develop evaluation and mutation strategies to handle the generated seed programs, facilitating efficient fuzzing execution while further enriching the diversity of the resulting test cases. We implement KQFuzz and conduct fuzzing on three popular quantum libraries, including Qiskit, PennyLane, and Cirq. Experimental results demonstrate that our approach significantly outperforms other state-of-the-art methods, with coverage improved by up to 18.44%. During the development of KQFuzz, we discovered 13 bugs, all of which have been confirmed and 12 have already been fixed by the developers.

We study stochastic optimization with heavy-tailed gradient noise. We first propose a novel quantum mean estimator for multivariate heavy-tailed random variables that achieves lower query complexity than optimal classical estimators in the low-dimensional regime. We further develop an unbiased quantum mean estimator by applying a generalized multi-level Monte Carlo technique. We prove quantum lower bounds showing that, when the dimension $d$ of the random vector is small and can be viewed as a constant, our quantum estimators are optimal up to logarithmic factors. We further derive stronger dimension-dependent lower bounds for tail index $p>4/3$, showing that a nontrivial dependence on the dimension is unavoidable in the low-dimensional regime. Based on these estimators, we propose a quantum normalized stochastic gradient descent method ($\texttt{QNSGD}$), which finds an $ε$-stationary point using $\tilde{\mathcal{O}}\big(\sqrt d\,ε^{-\frac{5p-4}{2p-2}}\big)$ queries to the quantum stochastic gradient oracle. For a convex objective function, we propose a quantum projected stochastic gradient descent method ($\texttt{QPSGD}$), which computes a solution with $ε$-optimal solution using $\tilde{\mathcal{O}}\big(\sqrt d\,ε^{-\frac{3p-2}{2p-2}}+ε^{-2}\big)$ queries in expectation. These sharper bounds improve upon the classical lower bounds $Ω\big(ε^{-\frac{3p-2}{p-1}}\big)$ for nonconvex problems and $Ω\big(ε^{-\frac{p}{p-1}}\big)$ for convex problems in the low-dimensional regimes $d\lesssimε^{-\frac{p}{p-1}}$ and $d\lesssimε^{-\frac{2-p}{p-1}}$, respectively.

Variational quantum circuits have been central to many proposed near-term applications of quantum computing, but a growing body of evidence suggests that trainability and quantum advantage are fundamentally at odds: ansätze expressive enough to resist efficient classical simulation tend to exhibit barren plateaus, while structures that provably rule out barren plateaus typically render them classically simulable. We propose a stacked linear combination of unitaries (S-LCU) as a variational ansatz which provides a tunable trade-off between barren plateaus and classical simulability. Using a diagrammatic analysis, we bound the loss-landscape variance of the Free Fermion S-LCU, whose elements are fermionic Gaussian unitaries. We prove a variance lower bound of $Ω(1/(n k^{3l}))$, with a simulation cost of $O(k^{2l} n^3)$ using the best known classical algorithm, compared to a quantum gate complexity of only $O(lkn^2)$. The number of layers $l$ serves as a single dial that trades computational complexity against the rate of cost concentration. This offers practitioners a systematic method for constructing ansätze with a complexity-trainability trade-off that best suits their application and hardware.

Multivariate time series forecasting (MTSF) predicts future values of multiple variables from historical data. While quantum neural networks have been increasingly applied to this task, they typically rely on fixed local measurements, which restrict their expressivity. We propose MTSF-ANO, a simple hybrid model for MTSF that integrates variational quantum circuits with adaptive non-local observables (ANO). On the four ETT datasets, MTSF-ANO ranks first or second in MSE in 17 of 20 settings, improving over the strongest baseline by up to 20% on ETTh1, and outperforms or matches its fixed local observable counterpart across all settings. Our ablations show how the quantum circuit design and ANO non-locality affect performance. These results suggest that ANO is a promising direction for quantum time series forecasting.

Quadratic unconstrained binary optimization (QUBO) has emerged as a powerful framework for medical computing problems. Binary decision variables naturally represent clinical choices, making QUBO formulations well-suited for quantum annealing hardware. However, a fundamental scalability challenge limits practical deployment: problem size grows rapidly with input dimensionality, creating computational bottlenecks that restrict applications to simplified scenarios. This paper addresses this challenge through hierarchical problem reduction, as demonstrated in medical image segmentation, where pixel-level QUBO formulations create over 65,000 variables for a 256x256 image, forcing existing approaches to downsample to 42x42 resolution and discard 97% of pixel information. A superpixel-based QUBO framework is proposed using simple linear iterative clustering (SLIC) to group pixels into perceptually meaningful regions, then formulate segmentation as QUBO over a region adjacency graph (RAG) combining min-cut and smoothness objectives. Validation on INbreast mammography breast cancer images demonstrates a 4.2% improvement in segmentation quality (mean IoU 0.76 vs 0.73) with 33 computational speedup (0.67s vs 21.97s) and a 97.3% reduction in problem size (1764 to 48 variables), all achieved while processing full-resolution images rather than downsampled versions. The reduced problem size also fits well within current quantum annealer connectivity limits, removing the embedding overhead that has historically blocked direct deployment of pixel-level QUBO segmentation on quantum hardware.

In this study, we developed and evaluated four conditional energy-based forecasting architectures: a classical Gaussian-Bernoulli CRBM, a hybrid quantum-classical QCRBM, a full-register QQRBM, and a lag-feature QFeatureQRBM with complete derivations of their conditional distributions, Contrastive-Divergence gradients, and hybrid training, bridging the energy-based formulation and the implementation-level quantum computation. Unlike prior comparisons, our evaluation enforces symmetric hyperparameter optimisation: classical and quantum-specific hyperparameters receive an equally thorough grid search across thirteen structured experiments. We test on two data classes, a Gaussian-process dataset (GP) generated with real financial data and the input-driven NARMA-10 nonlinear benchmark. Across both regimes we find no systematic evidence of a quantum advantage at the available sample size: no quantum architecture improves on the best classical baseline. The fully quantum QQRBM and QFeatureQRBM are significantly worse, whereas the hybrid QCRBM is statistically indistinguishable from the strongest classical CRBM on both datasets. A power analysis bounds this null result: at n = 12 only medium-to-large effects are detectable, so small advantages cannot be excluded. An iso-parameter (matched-budget) comparison reaches the same conclusion: the classical CRBM is lowest at three of the four budgets and no CRBM-vs-QCRBM difference is significant at any budget.

Short-term disturbances at major passenger railway stations alter train arrival and departure times as well as the release sequence of station resources. Effective recovery therefore requires coordinated adjustment of arrival-departure track allocation, station resource occupation, and train retiming. This study represents the station resources involved in train arrival, track occupancy, and departure operations as zone-level resource-occupation intervals. An arrival-departure track allocation adjustment model is formulated. Resource compatibility is imposed as the feasibility condition, while train delays and resource reassignment costs are jointly considered. A quantum-inspired evolutionary algorithm combined with neighborhood search (QEA-NS) is proposed to solve the model. Perturbation instances are constructed using GTFS timetable data from Frankfurt Hauptbahnhof, Germany. QEA-NS is compared with CP-SAT under the same candidate resource set and feasibility criteria. Both methods generate solutions satisfying the modeled resource compatibility constraints. QEA-NS yields a total delay of 388 min, compared with 519 min for CP-SAT, representing a reduction of 25.2%. The mean delay of delayed trains decreases from 4.99 to 3.73 min, although QEA-NS requires a longer solution time. Across 10 random perturbation instances, QEA-NS achieves lower total delay in every case. Its mean total delay and standard deviation are 390.5 min and 35.945 min, respectively, compared with 673.8 min and 105.739 min for CP-SAT. The results indicate that, under the adopted resource representation and constraints, QEA-NS improves the delay performance of recovery plans. Its computational efficiency, however, requires further improvement.

Communication complexity provides a natural framework for quantifying the classical resources required to reproduce quantum statistics. In the qubit prepare-and-measure scenario, two classical bits have been shown to be necessary and sufficient to simulate arbitrary qubit states and arbi- trary quantum measurements exactly. However, this result does not exclude the possibility that restricted families of measurements may admit accurate 1-bit classical approximations. We use a neural network procedure to demonstrate that a single bit can achieve high average accuracy for specific measurement families. A performance analysis of our neural network reveals that symmet- ric measurements with uniformly weighted elements, such as those forming regular polyhedra, are particularly amenable to this restricted communication. By analyzing the patterns learned by the neural network, we derive an analytical protocol that is extremely accurate for finite information- ally complete symmetric configurations and becomes exact in the limit of a continuous isotropic measurement.

Photonic-crystal surface-emitting lasers (PCSELs) can combine high-power operation with narrow-divergence surface emission, but optimizing coupled parameters requires costly full-wave simulations. Deep Q-network (DQN) optimization can reuse simulated transitions to guide edits, yet which value-learning mechanisms remain reliable under tight simulation budgets is unknown. We address this gap by comparing baseline DQN and six value-based variants for a seven-variable PCSEL design under a shared objective, simulator, 83-call budget, and four matched initializations. Beyond endpoints, we analyze sample efficiency, policy behavior, and physical response to separate learning gains from favorable starts or exploratory jumps. Dueling DQN is the only variant to improve all four seeds. Relative to the first evaluated designs, its selected structures increase the mean quality factor () from to (), reduce wavelength error by 64%, and increase upward power by 47%; compared with baseline DQN, they achieve a higher mean under the same budget. Other variants yield no consistent improvement; Double DQN reproduces baseline trajectories, while Rainbow-lite shows high upside but strong seed dependence. These results identify Dueling DQN as the most reliable configuration tested for simulation-budget-limited PCSEL inverse design and provide a reproducible framework for attributing algorithmic gains in scientific optimization. The source code is publicly available at https://github.com/Longying-Wen/PCSEL-RL.

Quantum devices are open systems whose dynamics interleave coherent evolution with dissipation, and benchmarking, error mitigation, and error correction all rest on a faithful model of both. Existing characterization protocols either assume prior knowledge of the interaction and noise structure, or demand ancillas, entangled probes, or mid-circuit control, or capture only the Pauli-diagonal part of the noise. Here, we present a protocol that reconstructs an arbitrary sparse Markovian generator, including every Hamiltonian together with the jump operator coefficients, using only product Pauli state preparation, single uninterrupted forward evolutions, and product Pauli measurements. Given a sparsity budget $M_0$ and a strength bound $Γ$ of the Lindbladian, every coefficient is learned to precision $ε$ from $\widetilde{O}(Γ^2M_0^2/ε^4)$ experiments and $\widetilde{O}(ΓM_0^2/ε^2)$ total evolution time, with both supports identified from data without locality assumptions. The protocol runs at a logarithmic number of positive evolution times on a hardware clock lattice and is provably robust to calibrated state-preparation and measurement errors.

We introduce a new class of fully-quantum Metropolis walks in which both the proposal and acceptance steps are intrinsically quantum. Unlike standard quantum walks obtained by quantizing classically efficient Markov chains, our algorithm employs Hamiltonian simulation as a quantum-native proposal mechanism, enlarging the class of quantum walks beyond classical counterparts. We target the problem of sampling from the low-temperature Gibbs distribution of classical dense Ising models, within a fixed error in total variation distance. This approach achieves about a cubic polynomial asymptotic advantage over previous quantum-walks, resulting in a total sixth-degree polynomial queries speedup compared to the best classical walk. This shows that speedups beyond the widely assumed quadratic limit are possible within the quantum walk formalism. We perform a complete fault-tolerant compilation of all algorithmic primitives and benchmark against CPU, GPU, and FPGA implementations of the best classical Markov chain. Under identical hardware assumptions, the resulting advantage runtime crossover is reduced from approximately $10^3$ years for conventional quantum walks to less than one day. These results identify fully-quantum Markov chains as a promising route toward practical quantum advantage.

A central design principle in modern machine learning and artificial intelligence is to align a model's inductive bias with the structure of its input data. For matrix-valued inputs, relevant matrix-level relationships can be characterised through spectral values and spectral subspaces; however, common coordinate-wise rotation-gate data-encoding unitaries used in most quantum machine learning models do not explicitly construct such a matrix-level representation. We introduce Quantum Spectral Models (QSMs), in which we construct the generator of the data-encoding unitary directly from each input matrix. We study three QSM variants based on symmetric, global block, and non-overlapping patch-local block Hamiltonians. Their outputs admit truncated Fourier representations in which input-dependent spectral gaps supply candidate phase carriers, while spectral subspaces help determine their coefficients. We evaluate the QSMs and comparison quantum models on two matrix representations of Pendigits and two controlled synthetic tasks defined by spectral statistics. At the largest evaluated circuit depth, QSM variants lead the tested quantum models in mean test accuracy across all four benchmarks. The patch-local QSM leads on Pendigits, whereas the global block-Hamiltonian QSM leads on the controlled spectral tasks. Ablations show a task-dependent reversal: subspace-preserving controls perform better on Pendigits, whereas spectral-value-only controls lead among the tested ablations on the synthetic tasks. Together, these results shed new light on quantum machine-learning model design by showing how input-conditioned spectral representations can provide an analysable inductive bias, while offering a broader perspective on structure-aware model design in machine learning and artificial intelligence.

Volatility forecasting is dominated by persistence and measurement noise, leaving limited residual structure for nonlinear models to exploit. We introduce Susceptible Architectures (SUSA), a reservoir-design principle for volatility forecasting, and its two concrete implementations, based on complex-valued open-chain and periodic reservoirs and regime-conditioned experts to interpret reservoir features across calm, onset, recovery, and persistent-stress states. We also implement open-system $q$-qubit counterparts in Qiskit while retaining a common AR-Ridge anchor and a bounded residual correction trained under QLIKE. We evaluate models on 16 U.S. equity and exchange-traded-fund series using three disjoint chronological training, validation, and test folds, a 12-observation input window, and a five-observation forecast horizon. The proposed models perform competitively with GARCH, achieving statistically significant QLIKE improvements for specific assets (IWM, XLP). Also models' forecasts complement HARQ-style predictions: a stacked ensemble improves mean QLIKE by 0.0116 over its strongest constituent and wins in 75% of test scenarios.

Quantum state preparation is a key component of many quantum algorithms. Performing this step efficiently is essential for realizing practical quantum advantage in quantum chemistry applications. Iterative algorithms like ADAPT-VQE can produce shallow ground-state preparation circuits, but become computationally prohibitive for the larger molecules relevant to materials science and pharmaceutical development. Here, we introduce ADAPT-GQE, a generative AI framework that learns to synthesize ground-state preparation circuits for electronic structure calculations. We first use ADAPT-VQE to generate high-quality reference circuits, which are then used as targets for training models for circuit generation. Once trained, the model can efficiently propose and score circuits, enabling reinforcement learning (RL) to drive circuit generation accuracy beyond the accuracy of the ADAPT-VQE training data. This pipeline achieves order-of-magnitude reductions in circuit generation time relative to ADAPT-VQE while maintaining comparable or improved state-preparation accuracy. We demonstrate ADAPT-GQE on imipramine, a well-established tricyclic antidepressant that serves as a representative, challenging target for computational modelling in drug stability protocols. We execute generated circuits on Quantinuum Helios-1, representing a milestone for AI-generated quantum chemistry circuits on state-of-the-art quantum hardware. These results establish a pathway toward automated quantum circuit synthesis for utility-scale quantum computational chemistry.

A central challenge in quantum machine learning is understanding the scaling behavior of parameterized quantum circuits (PQCs). In particular, it remains unclear how their performance on unseen data changes as the number of trainable parameters increases. Prior works have derived formal generalization guarantees for quantum models, but it is well-known that many such results do not fully characterize generalization behavior in practice. In this work, we show that gradient-based PQCs can exhibit improved performance on unseen data as model size increases, displaying the phenomenon of double descent. This contrasts with the traditional view that larger models lead to degraded generalization. We provide analytical results rigorously underpinning this behavior by leveraging add-one-in perturbation techniques and spectral properties of random matrices. We support these results with numerical experiments on re-uploading PQCs across several data sets and training set sizes, consistently observing the predicted double descent behavior. While other obstacles on the path toward practical quantum machine learning remain, our finding that deeper parameterized quantum circuits do not necessarily exhibit degraded performance provides reasons for cautious optimism.

Machine-learning surrogates of physical systems face a paradox: explainable models facing the challenge of expressivity to capture complex nonlinear flows, whereas expressive deep surrogates match high-fidelity simulations only through massive parameterisations that turn the learned dynamics into a black box. Here, we introduce quantum-compressed machine learning (QCML), which resolves this tension by compressing the latent propagator of a flow surrogate from $524{,}288$ trainable parameters to no more than $8$. This parameter reduction brings the learned dynamical law to the parameter scale of a physical constitutive relation rather than a black-box neural network, making the surrogate directly interpretable and controllable without sacrificing expressivity. The compression is realised by a structured quantum circuit whose unitary propagator constrains the latent spectrum to the unit circle exactly and by construction, replacing exponential error growth with linear accumulation over autoregressive rollouts. Classical regularisation only approximates this constraint: even a quantum-inspired classical baseline penalised towards unitarity collapses within one Lyapunov time on turbulent channel flow, whereas QCML remains stable over the full rollout. Shared phase and coupling angles parameterising the circuit correspond directly to modal frequencies and inter-mode interactions, giving the learned dynamics a physical interpretation in spectral space. On two patient-specific cardiovascular benchmarks, the structured QCML propagator matches the predictive accuracy of its classical counterpart on surface pressure spectra, pressure drop, and wall shear stress. These results establish QCML as a working component of scientific machine learning and a concrete contribution towards practical quantum advantage in real-world prediction.

Numerous studies have analyzed the use of hybrid quantum-classical convolutional neural networks as a promising alternative to classical deep learning. However, network components on quantum hardware impose fundamental limitations, while the scalability of quantum circuits leads to trainability issues. In this work, we investigate whether small, classically-emulated quantum circuit components can play a meaningful role within complex models, offering an alternative to purely classical convolutional architectures. To this end, we present a systematic study of the effectiveness of a Hybrid Quantum-inspired Convolutional Neural Network (HQiCNN) compared with a parameter-matched classical Convolutional Neural Network (CNN) that differs only in an intermediate dense neural layer. Both models are evaluated on two real-world medical datasets while systematically varying the different hyperparameters, ensuring a fair model comparison that is both dataset and hyperparameter independent. The results show that no architecture consistently dominates the other: the HQiCNN achieves its largest gains in intermediate-data regimes, whereas the CNN reaches the highest accuracies for the largest training sets in both datasets. Furthermore, removing entanglement produces comparable performance while enabling substantially better scalability of quantum simulations, and richer observable sets become beneficial only when sufficient training data are available. Finally, we propose two SHAP-based explainability tools for comparing the predictions between both models, $|SHAP|$IoU and $EMD_{pos}$ metric, to demonstrate that both architectures consistently attend to anatomically plausible regions. Thus, we provide a comprehensive benchmark showing that, under certain conditions, hybrid quantum-inspired models are an alternative that can offer benefits in practical tasks such as medical image classification.

Neural Radiance Fields (NeRF) have revolutionized novel view synthesis, yet their classical implementations remain computationally intensive for high-fidelity rendering. QNeRF recently demonstrated the feasibility of training NeRF on gate-based quantum computers by combining amplitude embedding, parameterized quantum circuits (PQCs), parity-based measurements, and volumetric rendering. However, QNeRF relies on classical sinusoidal positional encoding for spatial coordinates, which scales poorly with scene complexity and resolution. In this work, we replace the sinusoidal positional encoding for spatial coordinates with the multiresolution hash encoding from Instant-NGP while keeping the view-direction encoding, amplitude MLP, quantum circuit, parity measurement, output scaling, and volumetric rendering pipeline unchanged. This hybrid design, Hash-QNeRF, retains the quantum radiance prediction step while benefiting from the fast convergence and memory efficiency of learnable hash grids. On a synthetic Blender scene, we achieve a final training loss of 0.003534, corresponding to approximately 24.5 dB PSNR on the fitted batch. Noise resilience experiments using Qiskit FakeKyiv and FakeTorino backends yield state fidelities of 0.93 to 0.98, indicating that hash encoding does not degrade the quantum circuit's noise tolerance.

In this work, a quantum architecture search framework for approximate quantum state preparation (QSP) is proposed. QSP is a challenging task, since the search space grows exponentially with the number of qubits, making the identification of the optimal circuit non-trivial. To address this problem, deep reinforcement learning is employed through an agent based on proximal policy optimization. The objective of the agent is to identify the best possible approximation of the target state while simultaneously minimizing the number of gates used. At each step, the agent appends a new gate to the circuit and recomputes the fidelity between the approximated state and the target states. Various experiments have been performed from 2 to 5 qubits. Both predefined states, such as Bell, GHZ, W, and Dicke states, and completely random states are considered. The proposed framework is able to achieve approximation errors of $10^{-14}$.

Quantum Phase Estimation (QPE) is a foundational algorithm for molecular ground-state energy estimation, but its deep circuit requirements make direct hardware execution impractical on Noisy Intermediate-Scale Quantum (NISQ) devices. We present an analytically grounded variational surrogate framework in which a shallow Variational Quantum Circuit (VQC) is trained to reproduce the QPE measurement distribution without any quantum circuit simulation. The training target is computed entirely classically via the Dirichlet kernel, evaluated directly from the Full Configuration Interaction (FCI) ground-state energy, the ancilla qubit count, and the time evolution parameter, eliminating the exponentially scaling simulation bottleneck of prior surrogate approaches. We apply this framework to the hydrogen molecule (H$_2$) with a symmetry-tapered Hamiltonian, conducting a four-stage experimental investigation on IBM Quantum hardware. Stage 1 compares linear and full entangler topologies for the $R_Y$-$R_Z$-$CZ$ ansatz, with and without XpXm Dynamical Decoupling (DD), across four distributional metrics (Hellinger distance, fidelity error, total variation distance, Jensen-Shannon divergence), identifying the linear entangler as optimal. Stage 2 varies VQC layers ($p=1$ to $5$) for the linear-entangler ansatz, identifying single-layer depth as optimal under hardware noise. Stage 3 applies this configuration to the reduced $R_Y$-$CZ$ ansatz, comparing ideal and noisy simulator-trained parameters. A supplementary noise analysis at $p \in \{8,64\}$ characterizes the depth-dependent interplay between circuit depth and DD effectiveness. The framework enables faithful QPE mimicry using a linearly scaling VQC, recovering the ground-state energy within the chemical accuracy threshold (1 kcal/mol), constituting a scalable, hardware-efficient paradigm for QPE-based molecular energy estimation on NISQ devices.

Scaling semiconductor quantum dot arrays toward fault-tolerant quantum computing requires efficient tuneup of spin qubits, a process that depends on the analysis of charge stability maps (CSMs) and remains largely manual. While machine learning has been widely applied to CSM analysis in reservoir-coupled devices, automated tuning in the increasingly important isolated-mode regime has received limited attention. In isolated-mode CSMs, charge transitions appear as near-vertical lines, making them well suited to compact, task-specific models. We present two convolutional neural networks with fewer than one million parameters, trained on CSMs collected from 32 silicon metal-oxide-semiconductor (SiMOS) double-quantum-dot devices measured at approximately 1 K using an automated cryogenic probing system. Sixteen devices were used for training and sixteen were held out to evaluate cross-device generalization against hand-labeled ground truth. CSMClassifier identifies charge instability and sensor artifacts, achieving 94% macro-averaged accuracy across three quality classes on 2,407 held-out images. ChargeLineNet localizes charge-transition lines and determines electron occupancy, achieving 95.3% exact line-count accuracy on 1,131 held-out images. Combined into a single pipeline, the models correctly determine electron occupancy for 93.8% of clean held-out images. Pre-training on synthetic images substantially improves label efficiency. Fine-tuning the pre-trained model on limited experimental data maintains over 90% accuracy, whereas training from scratch degrades significantly under the same conditions. Together, the two models occupy only 6.5 MB and process images in less than 60 ms on standard laboratory hardware, demonstrating a practical path toward scalable, automated characterization and tuneup of quantum-dot devices.

Quantum-kernel methods encode a dataset's geometry in a Gram matrix, so learning claims on hardware kernels assume the intended geometry survives execution. We measure that survival for one frozen four-qubit ZZ feature-map kernel on $N=24$ real indoor air-quality windows, reconstructed on ibm_fez (1024 shots per circuit) under baseline, dynamical decoupling alone, and gate twirling alone, each a single non-interleaved job. Every configuration returned a complete, finite, positive-semidefinite Gram matrix and preserved the centered statevector geometry to a substantial but incomplete descriptive degree (full-matrix centered kernel alignment, CKA, 0.933-0.989). Gate twirling was most faithful on every reported geometry axis, with the only jackknife-resolved improvement over baseline (persisted Spearman, mean absolute error, and full-matrix CKA diagnostics); dynamical decoupling alone was not separated from baseline at the frozen-window scale. Residual hardware distortion, not finite sampling, dominates the discrepancy. Yet fidelity and label alignment were reversed: the most faithful configuration had the lowest centered kernel-target alignment, which sits at or below label-permutation references for statevector and hardware alike. We read the small hardware uplift as a normalization property of the non-affine distortion, not captured signal. These are descriptive results for single jobs on one backend, not causal mitigation-efficacy estimates; no quantum-advantage, hardware-classifier-superiority, or forecasting claim is made. Implementation fidelity and task relevance are distinct axes; hardware quantum machine-learning studies should report both.

Quantum machine learning (QML) algorithms in high energy physics (HEP) can efficiently represent and leverage long-range, high-order correlations in high-dimensional collider data, potentially with fewer parameters and favorable scaling relative to classical models. Deployment of QML in real-time collider applications such as trigger systems requires the ability to emulate and compile quantum circuits classically, then synthesize the resulting quantum gates onto low-latency hardware accelerators, namely field-programmable gate arrays (FPGAs). We present a study of variational quantum autoencoder models for real-time anomaly detection triggers in modern collider experiments. The models achieve performance comparable to state-of-the-art classical approaches and, after FPGA synthesis, satisfy resource usage and timing constraints consistent with trigger applications in future colliders. This work provides one of the first FPGA implementations of QML models for HEP triggers, enabling higher-capability models in today's classical data acquisition pipelines while advancing quantum readiness of collider experiment infrastructure.

While combinatorial optimization problems are central to many scientific and engineering applications, their solution remains challenging due to exponentially large search spaces. Variational quantum algorithms offer a promising route for tackling such problems, yet their practical performance is limited by repeated quantum circuit evaluations and classical parameter updates. In this work, we introduce DQAOA-GPT, a hybrid framework that integrates the distributed quantum approximate optimization algorithm (DQAOA), which decomposes a large optimization problem into smaller sub-problems, with GPT-based quantum circuit generation for solving those sub-problems. Rather than relying on iterative variational optimization, the proposed approach uses a trained generative model to directly generate high-quality quantum circuits for the decomposed sub-problems. As a benchmark, we evaluate DQAOA-GPT against conventional DQAOA on dense HUBO optimization problems with up to 100 decision variables. The results demonstrate that DQAOA-GPT significantly reduces computational cost while maintaining competitive solution quality, with larger acceleration observed for larger sub-problem sizes. Although this work focuses on benchmark-scale validation, the framework provides a promising foundation for larger-scale combinatorial optimization in hybrid HPC-QC environments through increased GPU resources and parallel computing capability.

Physical noise in near-term quantum hardware is usually treated as a nuisance to suppress. We ask whether it can instead act as a hardware-native regularizer for photonic hybrid quantum-classical neural networks (PHQCNNs), analogous to noise-injection regularization in classical deep learning. Using Quandela's Perceval simulator and the MerLin framework, we build PHQCNNs for Iris, Digits, and MNIST and inject Perceval's seven-parameter physical noise model directly into training. A genetic algorithm searches the six continuous noise dimensions and 1 boolean parameter to find, per dataset, the configuration maximizing validation accuracy, compared against a noiseless baseline across five seeds. GA-tuned noise yields modest accuracy gains on Iris (+0.82pp) and Digits (+1.45pp), but a clear degradation on MNIST (-1.21pp). Per-parameter sweeps show that no individual noise parameter is consistently beneficial, motivating the joint search, while a second-order loss expansion shows that physical noise induces a Tikhonov-like regularization term whose effect is dataset-dependent. Physical photonic noise can thus act as a free regularizer, but not universally.

Kernel methods are powerful tools in machine learning but commonly used full-Gram kernels face three key limitations: (1) quadratic scaling with training set size; (2) the use of fixed, non-trainable kernels; and (3) the absence of an intrinsic formulation for multiclass classification. We present McQuack, a trainable quantum kernel method for multiclass problems that achieves linear scaling in the number of training samples. This is accomplished by replacing the full training-set Gram matrix with a trainable sample-to-(class-centroid) fidelity matrix. We evaluate the model in simulation and on 124 qubits of two IBM devices, across more than 150 datasets. In simulation, McQuack outperforms existing "pure" quantum baselines, while results from hardware inference -- obtained without training -- achieve performance similar to an RBF kernel. Finally, we study the trainability of the model and observe no evidence of barren plateaus in our experiments with up to 13 qubits, and highlight the importance of parameter initialization for successful optimization.

Quantum federated learning enables distributed clients to train quantum neural networks without sharing local data, making it promising for privacy-aware intelligent services. Intelligent services in this context refer to privacy-sensitive distributed decision systems, such as fraud detection and genomic classification, where reliable and fair client-level learning is as important as the accuracy of the aggregate model. However, heterogeneous client data and noisy quantum optimization often cause unstable local updates, client drift, and unfair performance between clients. This paper proposes DUQFL-Prox, a drift-stable quantum federated learning framework based on deep-unfolded local optimization. Instead of using a fixed local optimizer, each client performs adaptive unfolded SPSA updates, while a proximal term keeps the local model close to the global model. A lightweight controller learns step-specific optimization parameters to improve post-aggregation performance. Experiments on financial fraud and genomic classification tasks show that DUQFL-Prox improves stability, generalization, and client fairness compared with standard QFL baselines. The results suggest that deep-unfolded quantum federated learning can support more reliable and fair intelligent services in heterogeneous distributed environments.

Quantum error correction can be enhanced by post-selecting out runs that are likely to produce a logical failure, but the most accurate measures for that require costly decoder-level information. We introduce a practical, decoder-agnostic post-selection method that learns directly from syndrome data. The method trains a supervised classifier to distinguish between syndromes from low- and high-noise regimes, and then uses the classifier's output as an abort score for new runs, without requiring logical-error labels, correction operators, or code-specific likelihood calculations. We validate the approach in three complementary settings: circuit-level simulations of the Gross bivariate-bicycle code, code-capacity simulations of the surface code, and experimental logical magic-state distillation data from the QuEra neutral-atom processor. In the Gross and surface codes, learned syndrome post-selection reduces the conditional logical error rate at a fixed acceptance rate, with performance comparable to syndrome-weight filtering. For the surface code, the learned classifier reveals a post-selection transition distinct from the conventional decoding threshold. In the experimental data, the machine-learning score outperforms syndrome-weight post-selection and, when combined with logical-gap filtering, improves the output fidelity beyond using the logical gap alone. These results show that syndrome-only learning provides a scalable and hardware-compatible route to improving the reliability of quantum error correction.

Quantum reservoir computing (QRC) uses fixed quantum dynamics as a high-dimensional temporal feature map and trains only a lightweight classical readout. QRC is attractive for near-term quantum machine learning, but its performance depends strongly on architecture choices such as input encoding, reservoir depth, entanglement topology, measurement features, state-reset policy, feature construction, and readout regularization. We introduce \method, a simulator-based benchmark that formulates QRC design as constrained black-box architecture search and evaluates whether large language models can act as proposal controllers for this search problem. The benchmark compares five policies under identical evaluation budgets: random search, evolutionary search, Bayesian/TPE optimization, a feedback-based LLM agent, and \hybrid, which combines LLM proposals with memory, mutation, crossover, duplicate avoidance, and exploration. On NARMA10, Mackey-Glass forecasting, and temporal parity, \hybrid{} is the most consistent policy: it ranks first on NARMA10 and temporal parity and second on Mackey-Glass, narrowly behind evolutionary search. Under a 25-evaluation budget and three seeds, \hybrid{} improves over random search on all tasks, including a 23.6% relative reduction in Mackey-Glass error. The results do not show that LLMs are universal QRC optimizers; rather, they show that generative models can be useful high-level controllers when embedded inside validated, reproducible hybrid search loops.