Wearable Devices

Rehabilitation aims to help patients with limited mobility regain their physical abilities through targeted movements, exercises, stimulation, and other therapeutic methods. Recent advances in technology have introduced sensor-based systems into rehabilitation and clinical practices, enabling real-time monitoring and providing accurate feedback on movement accuracy. Among these sensors, LiDAR has demonstrated strong potential, offering key advantages over conventional techniques such as camera-based systems, which raise privacy concerns, and wearable sensors, which can be uncomfortable and prone to errors. In this work, we review the applications of LiDAR in rehabilitation, post-injury care, and hospital environments, focusing on studies published between 2019 and 2025. Studies across several areas have been explored: 3D body scanning and gait analysis with standalone LiDAR, LiDAR mounted on robotic systems for rehabilitation, real-time monitoring and environment scanning for safe navigation, and activity and position recognition. We also analyze processing techniques, particularly learning-based approaches, and support the discussion with statistical analysis, highlighting trends, gaps, and future research opportunities. To the best of our knowledge, this is the first comprehensive survey dedicated to LiDAR for rehabilitation applications, providing an overview of current methods, AI-based processing techniques, and open challenges.

Hypertensive disorders of pregnancy remain a leading cause of maternal and fetal morbidity worldwide, yet diagnosis relies on intermittent cuff-based blood pressure measurements that are prone to bias and fail to capture continuous physiological dynamics. Growing evidence suggests that fetal cardiovascular activity is associated with maternal-placental hemodynamics and may encode markers of maternal hypertension. To analyze this, we collected a large-scale dataset of fetal one-dimensional Doppler ultrasound recordings paired with maternal blood pressure from 3,255 pregnant women across 8,170 antenatal visits in rural Guatemala. We developed AutoHyPE, a hierarchical attention network that models short- and long-term signal structure, incorporating a novel prototype-based contrastive learning and multi-view strategy to enhance representation robustness under long-tailed class distribution and biological variability. AutoHyPE achieved an AUROC of 0.80 for maternal hypertension detection, outperforming baseline approaches while maintaining balanced performance across classes, with no performance degradation in an edge deployment scenario. Our findings demonstrated that fetal cardiac mechanical activity contains hemodynamic features indicative of maternal hypertension status. This supports a promising paradigm shift toward continuous, objective monitoring of maternal health using existing, low-cost ultrasound technology and introduces a complementary approach to traditional methods based on blood pressure measurements, advancing scalable prenatal care.

Wearable devices running Human Activity Recognition(HAR) on Inertial Measurement Units~(IMUs) waste energy by performing continuous classification for each window, even during long periods of unchanged activity. We address this with a lightweight change-detection gate: a non-parametric algorithm based on dynamic template matching that runs continuously at only approximately 16kFLOPs per step, requires no offline training, and does not need prior definition of target activity classes. The gate invokes the full HAR network only when it detects an activity change, reducing the computational load by over 67% in realistic monitoring settings. The algorithm is evaluated on smart glasses, smartwatch, and smartphone data, requiring only a brief device-specific calibration phase. The gate achieves 98% sensitivity on UCA-EHAR, ensuring no genuine activity transition is missed, while 75% specificity keeps unnecessary HAR invocations low. Results on WISDM are 97% sensitivity and 76% specificity, demonstrating robustness and flexibility to various settings.

Understanding human activities and their surrounding environments typically relies on visual perception, yet cameras pose persistent challenges in privacy, safety, energy efficiency, and scalability. We explore an alternative: 4D perception without vision. Its goal is to reconstruct human motion and 3D scene layouts purely from everyday wearable sensors. For this we introduce IMU-to-4D, a framework that repurposes large language models for non-visual spatiotemporal understanding of human-scene dynamics. IMU-to-4D uses data from a few inertial sensors from earbuds, watches, or smartphones and predicts detailed 4D human motion together with coarse scene structure. Experiments across diverse human-scene datasets show that IMU-to-4D yields more coherent and temporally stable results than SoTA cascaded pipelines, suggesting wearable motion sensors alone can support rich 4D understanding.

Timely and interpretable early warning of sepsis remains a major clinical challenge due to the complex temporal dynamics of physiological deterioration. Traditional data-driven models often provide accurate yet opaque predictions, limiting physicians' confidence and clinical applicability. To address this limitation, we propose a Large Language Model (LLM)-guided temporal simulation framework that explicitly models physiological trajectories prior to disease onset for clinically interpretable prediction. The framework consists of a spatiotemporal feature extraction module that captures dynamic dependencies among multivariate vital signs, a Medical Prompt-as-Prefix module that embeds clinical reasoning cues into LLMs, and an agent-based post-processing component that constrains predictions within physiologically plausible ranges. By first simulating the evolution of key physiological indicators and then classifying sepsis onset, our model offers transparent prediction mechanisms that align with clinical judgment. Evaluated on the MIMIC-IV and eICU databases, the proposed method achieves superior AUC scores (0.861-0.903) across 24-4-hour pre-onset prediction tasks, outperforming conventional deep learning and rule-based approaches. More importantly, it provides interpretable trajectories and risk trends that can assist clinicians in early intervention and personalized decision-making in intensive care environments.

Construction workers are highly vulnerable to heat stress, yet tools that translate real-time physiological data into actionable safety intelligence remain scarce. This study addresses this gap by developing and evaluating deep learning models, specifically a baseline Long Short-Term Memory (LSTM) network and an attention-based LSTM, to predict heat stress among 19 workers in Saudi Arabia. Using Garmin Vivosmart 5 smartwatches to monitor metrics such as heart rate, HRV, and oxygen saturation, the attention-based model outperformed the baseline, achieving 95.40% testing accuracy and significantly reducing false positives and negatives. With precision, recall, and F1 scores of 0.982, this approach not only improves predictive performance but also offers interpretable results suitable for integration into IoT-enabled safety systems and BIM dashboards, advancing proactive, informatics-driven safety management in the construction industry.

Owing to the recent advancements in wearable devices for health care, the importance of BP estimation without cuffs increases. Cuff technologies are inappropriate for continuous BP measurement due to their inconvenient usage, invasive character, necessity of calibration, large size, and inability to perform long-term monitoring. Normally, the algorithm used for cuffless BP prediction employs machine learning models that operate according to the data-driven approach. However, although they show high numerical accuracy, ML models do not provide any interpretability, resulting in poor physiological validity and clinical applicability. We propose a combination of Windkessel and ML models that incorporates the physical aspects into the latter one. It is performed by reformulating Windkessel into a form that will allow employing ML models. The result is a system of ODEs which can be used in the neural network. Thus, the inclusion of physical constraints improves the data-driven approach by making models consistent with physics, understandable, and robust. For illustration, we apply the described technique using a publicly available MIMIC-II database that we obtain from the UCI Machine Learning Repository.

The physicality of exercise makes the role of athletic trainers unique. Their physical presence allows them to guide a student through a motion, demonstrate an exercise, and give intuitive feedback. Robot quadrupeds are also embodied agents with robust agility and athleticism. In our work, we investigate whether a robot quadruped can serve as an effective and enjoyable personal trainer device. We focus on a case study of interval training for runners: a repetitive, long-horizon task where precision and consistency are important. To meet this challenge, we propose SNOOPIE, an autonomous robot quadruped pacer capable of running interval training exercises tailored to challenge a user's personal abilities. We conduct a set of user experiments that compare the robot trainer to a wearable trainer device--the Apple Watch--to investigate the benefits of a physical embodiment in exercise-based interactions. We demonstrate 60.6% better adherence to a pace schedule and were 45.9% more consistent across their running speeds with the quadruped trainer. Subjective results also showed that participants strongly preferred training with the robot over wearable devices across many qualitative axes, including its ease of use (+56.7%), enjoyability of the interaction (+60.6%), and helpfulness (+39.1%). Additional videos and visualizations can be found on our website: https://sites.google.com/view/snoopie

The miniaturisation of neural processing units (NPUs) and other low-power accelerators has enabled their integration into microcontroller-scale wearable hardware, supporting near-real-time, offline, and privacy-preserving inference. Yet physiological signal analysis has remained infeasible on such hardware; recent Transformer-based models show state-of-the-art performance but are prohibitively large for resource- and power-constrained hardware and incompatible with $μ$NPUs due to their dynamic attention operations. We introduce PhysioLite, a lightweight, NPU-compatible model architecture and training framework for ECG/EMG signal analysis. Using learnable wavelet filter banks, CPU-offloaded positional encoding, and hardware-aware layer design, PhysioLite reaches performance comparable to state-of-the-art Transformer-based foundation models on ECG and EMG benchmarks, while being <10% of the size ($\sim$370KB with 8-bit quantization). We also profile its component-wise latency and resource consumption on both the MAX78000 and HX6538 WE2 $μ$NPUs, demonstrating its viability for signal analysis on constrained, battery-powered hardware. We release our model(s) and training framework at: https://github.com/j0shmillar/physiolite.

We introduce Sonata, a compact latent world model for six-axis trunk IMU representation learning under clinical data scarcity. Clinical cohorts typically comprise tens to hundreds of patients, making web-scale masked-reconstruction objectives poorly matched to the problem. Sonata is a 3.77 M-parameter hybrid model, pre-trained on a harmonised corpus of nine public datasets (739 subjects, 190k windows) with a latent world-model objective that predicts future state rather than reconstructing raw sensor traces. In a controlled comparison against a matched autoregressive forecasting baseline (MAE) on the same backbone, Sonata yields consistently stronger frozen-probe clinical discrimination, prospective fall-risk prediction, and cross-cohort transfer across a 14-arm evaluation suite, while producing higher-rank, more structured latent representations. At 3.77 M parameters the model is compatible with on-device wearable inference, offering a step toward general kinematic world models for neurological assessment.

In principle, deep generative models can be used to perform domain adaptation; i.e. align the input feature representations of test data with that of a separate discriminative model's training data. This can help improve the discriminative model's performance on the test data. However, generative models are prone to producing hallucinations and artefacts that may degrade the quality of generated data, and therefore, predictive performance when processed by the discriminative model. While uncertainty quantification can provide a means to assess the quality of adapted data, the standard framework for evaluating the quality of predicted uncertainties may not easily extend to generative models due to the common lack of ground truths (among other reasons). Even with ground truths, this evaluation is agnostic to how the generated outputs are used on the downstream task, limiting the extent to which the uncertainty reliability analysis provides insights about the utility of the uncertainties with respect to the intended use case of the adapted examples. Here, we describe how decision-theoretic uncertainty quantification can address these concerns and provide a convenient framework for evaluating the trustworthiness of generated outputs, in particular, for domain adaptation. We consider a case study in photoplethysmography time series denoising for Atrial Fibrillation classification. This formalises a well-known heuristic method of using a downstream classifier to assess the quality of generated outputs.

Multivariate time series classification (MTSC) plays a crucial role in various domains, including biomedical signal analysis and motion monitoring. However, existing approaches, particularly deep learning models, often require high computational resources, making them unsuitable for real-time applications or deployment on low-cost hardware, such as IoT devices and wearable systems. In this paper, we propose the Univariate Channel Fusion (UCF) method to deal with MTSC efficiently. UCF transforms multivariate time series into a univariate representation through simple channel fusion strategies such as the mean, median, or dynamic time warping barycenter. This transformation enables the use of any classifier originally designed for univariate time series, providing a flexible and computationally lightweight alternative to complex models. We evaluate UCF in five case studies covering diverse application domains, including chemical monitoring, brain-computer interfaces, and human activity analysis. The results demonstrate that UCF often outperforms baseline methods and state-of-the-art algorithms tailored for MTSC, while achieving substantial gains in computational efficiency, being particularly effective in problems with high inter-channel correlation.

Accurate assessment of lithium-ion battery ageing is challenged by cell-to-cell variability, heterogeneous cycling protocols, and limited transferability of data-driven models across datasets. In particular, robust identification of degradation transitions, such as the knee point, and reliable early-life prediction of remaining useful life (RUL) remain open problems. This study proposes a unified framework for battery ageing analysis based on continuous representations of voltage-capacity and capacity-cycle trajectories learned from heterogeneous public datasets (NASA, CALCE, ISU-ILCC). The continuous formulation enables consistent extraction of degradation descriptors, including curvature, plateau length and knee-related metrics, while reducing sensitivity to dataset-specific discretisation. Across more than 250 cells, statistically significant correlations between knee onset and end-of-life (Pearson 0.75-0.84) are observed. Additional early-life analysis confirms that knee-related features retain predictive value when estimated from partial trajectories. Early-life models provide increasingly stable RUL predictions as the number of observed cycles increases, with meaningful predictive performance emerging within the first 5-20 cycles and remain robust under cross-dataset domain shift. The framework integrates continuous modelling, feature extraction and uncertainty-aware prediction, providing an interpretable and dataset-consistent approach demonstrating robustness across heterogeneous dataset types. Compared with conventional discrete or feature-based methods, the proposed representation reduces sensitivity to sampling resolution and improves cross-dataset consistency. The study is limited to laboratory-scale datasets and capacity-based end-of-life definitions.

Stroke patient cross-subject electroencephalography (EEG) decoding of motor imagery (MI) brain-computer interface (BCI) is essential for motor rehabilitation, yet lesion-related abnormal temporal dynamics and pronounced inter-patient heterogeneity often undermine generalization. Existing adaptation methods are easily misled by pathological slow-wave activity and unstable target-domain pseudo-labels. To address this challenge, we propose PA-TCNet, a pathology-aware temporal calibration framework with physiology-guided target refinement for stroke motor imagery decoding. PA-TCNet integrates two coordinated components. The Pathology-aware Rhythmic State Mamba (PRSM) module decomposes EEG spatiotemporal features into slowly varying rhythmic context and fast transient perturbations, injecting the fused pathological context into selective state propagation to more effectively capture abnormal temporal dynamics. The Physiology-Guided Target Calibration (PGTC) module constructs source-domain sensorimotor region-of-interest templates, imposing physiological consistency constraints and dynamically refining target-domain pseudo-labels, thereby improving adaptation reliability. Leave-one-subject-out experiments on two independent stroke EEG datasets, XW-Stroke and 2019-Stroke, yielded mean accuracies of 66.56% and 72.75%, respectively, outperforming state-of-the-art baselines. These results indicate that jointly modeling pathological temporal dynamics and physiology-constrained pseudo-supervision can provide more robust cross-subject initialization for personalized post-stroke MI-BCI rehabilitation. The implemented code is available at https://github.com/wxk1224/PA-TCNet.

The Internet of Medical Things (IoMT) enables intelligent healthcare services but faces challenges such as dynamic topology, energy constraints, and diverse QoS requirements. This paper proposes QQMR, a Q-learning-based QoS-aware multipath routing method for WBANs. QQMR classifies data into three priority levels and employs adaptive multi-level queuing and fuzzy C-means clustering to optimize routing decisions. It maintains separate learning policies for each data type and selects primary and backup paths accordingly. Experimental results demonstrate improved packet delivery ratio and significant reductions in delay, routing overhead, and energy consumption compared to existing methods.

Consumer wearables enable continuous measurement of physiological data related to stress and recovery, but turning these streams into actionable, personalized stress-management recommendations remains a challenge. In practice, users often do not know how a given intervention, defined as an activity intended to reduce stress, will affect heart rate (HR), heart rate variability (HRV), or inter-beat intervals (BBI) over the next 15 to 120 minutes. We present a framework that predicts post-intervention trajectories and the direction of change for these physiological indicators across time windows. Our methodology combines a Transformer model for multi-horizon trajectories of percent change relative to a pre-intervention baseline, direction-of-change calls (positive, negative, or neutral) at each horizon, and an empirical study using wearable sensor data overlaid with user-tagged events and interventions. This proof of concept shows that personalized post-intervention prediction is feasible. We encourage future integration into stress-management tools for personalized intervention recommendations tailored to each person's day following further validation in larger studies and, where applicable, appropriate regulatory review.

Wearable devices generate continuous physiological and behavioral data, but converting these signals into clinically reviewable biomarker hypotheses remains labor-intensive. We introduce CoDaS, an AI co-data-scientist that integrates multi-agent hypothesis generation, deterministic statistical analysis, adversarial validation and literature-grounded interpretation under human oversight. Across three wearable cohorts comprising 9,279 participant-observations, CoDaS prioritized candidate associations for mental-health and metabolic endpoints after internal checks for replication, stability, robustness and leakage. The system identified related circadian-instability signals associated with depression, including sleep-duration variability in DWB ($ρ$ = 0.252, $p$ < 0.001) and sleep-onset variability in GLOBEM ($ρ$ = 0.126, $p$ < 0.001), and derived a wearable cardiovascular-fitness index associated with insulin resistance (steps/resting heart rate; $ρ$ = -0.374, $p$ < 0.001). Adding these features to demographic models produced modest gains ($ΔR^2$ = 0.040 for depression, 0.021 for insulin resistance). In a 12-clinician review totaling approximately 25 active hours, clinician validity judgments aligned with CoDaS confidence tiers ($ρ$ = 0.67, $p$ = 0.005), whereas added clinical value and confidence to act were rated lower. CoDaS supports traceable, hypothesis-generating prioritization of wearable candidate biomarkers.

Purpose. Athlete monitoring is constrained by small cohorts, heterogeneous biomarker scales, limited feasibility of repeated sampling, and the lack of reliable injury ground truth. These limitations reduce the interpretability and utility of traditional univariate and binary risk models. This study addresses these challenges by proposing an unsupervised multivariate framework to identify latent physiological states in athletes using real data. Methods. We propose a modular computational framework that operates in the joint biomarker space, integrating preprocessing, clinical safety screening, unsupervised clustering, and centroid-based physiological interpretation. Profiles are learned exclusively from amateur soccer players during a competitive microcycle. Synthetic data augmentation evaluates robustness and scalability. Ward hierarchical clustering supports monitoring and etiological differentiation, while Gaussian Mixture Models (GMM) enable structural stability analysis in high-dimensional settings. Results. The framework identifies coherent profiles that distinguish mechanical damage from metabolic stress while preserving homeostatic states. Synthetic data augmentation demonstrates feasibility and detection of latent silent risk phenotypes typically missed by univariate monitoring. Structural analyses indicate robustness under augmentation and higher-dimensional settings. Conclusion. The framework enables interpretable identification of latent physiological states from multivariate biomarker data without injury labels. By distinguishing mechanisms and revealing silent risk patterns not captured by conventional monitoring, it provides actionable insights for individualized athlete monitoring and decision making.

Active noise cancellation (ANC) is widely deployed on consumer headphones and earbuds to suppress environmental noise. However, existing ANC systems require an error microphone at the user's ear canal to measure residual sound, preventing deployment on emerging open-ear wearable devices such as smart glasses and VR headsets, which leave the ear unoccluded. Here we present an ANC system for open-ear wearables that suppresses environmental noise using only microphones and miniaturized open-ear speakers embedded within the frame of the wearables, removing the need for an in-ear error microphone. Our low-latency computational pipeline uses a neural network to estimate the noise at the ear from an array of eight microphones distributed around the wearable's frame and generates an anti-noise signal in real-time. This mapping generalizes to unseen users and acoustic environments without prior acoustic measurement. We develop a custom glasses prototype and evaluate across eleven unseen users and eight unseen environments under mobility in the 100 to 1000 Hz frequency range, where environmental noise is concentrated. We achieve a mean noise reduction of 9.6 dB without any calibration, and 11.2 dB with a brief user-specific calibration. Further, we demonstrate that our approach extends to the broader class of open-ear wearables including VR headsets and headbands.

The rise of large language models (LLMs) has shifted time series analysis from narrow analytics to general-purpose reasoning. Yet, existing benchmarks cover only a small set of health time series modalities and tasks, failing to reflect the diverse domains and extensive temporal dependencies inherent in real-world physiological modeling. To bridge these gaps, we introduce HEARTS (Health Reasoning over Time Series), a unified benchmark for evaluating hierarchical reasoning capabilities of LLMs over general health time series. HEARTS integrates 16 real-world datasets across 12 health domains and 20 signal modalities, and defines a comprehensive taxonomy of 110 tasks grouped into four core capabilities: Perception, Inference, Generation, and Deduction. Evaluating 16 state-of-the-art LLMs on more than 20K test samples reveals intriguing findings. First, LLMs substantially underperform specialized models, and their performance is only weakly related to general reasoning scores. Moreover, LLMs often rely on simple heuristics and struggle with multi-step temporal reasoning. Finally, performance declines with increasing temporal complexity, with similar failure modes within model families, indicating that scaling alone is insufficient. By making these gaps measurable, HEARTS provides a standardized testbed and living benchmark for developing next-generation LLM agents capable of reasoning over diverse health signals.

Human-machine interfaces in industrial automation need sensing modules that monitor operator actions and physiological state. This is important in factories, vehicles, machinery cabins, and human-robot collaboration, where workload, stress, fatigue, or reduced attention can affect safety. RGB monitoring is limited by low light, shadows, and privacy concerns, while thermal infrared imaging captures skin temperature dynamics without visible illumination. This paper studies thermal video as a contactless computer vision modality for estimating electrodermal activity (EDA), heart rate (HR), and breathing rate (BR), with the goal of supporting adaptive human-machine interfaces and operator-state awareness. We propose a signal-processing pipeline that tracks facial regions, aggregates thermal signals, and separates slow sudomotor trends from faster cardiorespiratory components. HR is estimated using orthogonal matrix image transformation (OMIT) across multiple facial regions, while BR is estimated from nasal and cheek thermal signals using spectral peak detection. We characterize 288 ROI-method configurations against contact references with lag-tolerant metrics using 31 sessions from the public SIMULATOR STUDY 1 (SIM1) driver monitoring dataset. The best fixed EDA configuration reaches a mean absolute correlation of $0.40 \pm 0.23$ against palm EDA, with individual sessions reaching $0.89$. BR estimation achieves $3.1 \pm 1.1$ bpm mean absolute error, while HR estimation yields $13.8 \pm 7.5$ bpm MAE, limited by the $7.5$ Hz thermal camera frame rate. The results show that thermal video provides useful respiratory and sudomotor cues, while revealing limitations caused by ROI selection, polarity changes, latency, and subject variability. These findings provide baseline design guidance for thermal computer vision as an auxiliary sensing layer in adaptive industrial HMI systems.

Reliable long-term decoding of gestures from surface electromyography (EMG) is hindered by signal drift caused by electrode displacement, muscle fatigue, and/or posture changes. Although modern models achieve high intra-session accuracy, their performance often degrades substantially across recording sessions. Existing approaches to mitigate this problem typically rely on large training datasets or computationally intensive pipelines that are unsuitable for energy-efficient wearable devices. We propose a lightweight test-time adaptation framework for EMG decoding. The framework includes three complementary adaptation strategies: (i) causal adaptive batch normalization for online statistical alignment, (ii) Gaussian Mixture Model alignment with experience replay to mitigate forgetting, and (iii) meta-learning for rapid few-shot calibration. We evaluate these methods on the multi-session NinaPro DB6 dataset. All approaches substantially improve inter-session robustness relative to a non-adaptive baseline while maintaining low computational overhead. Replay-regularized statistical alignment provides the most stable adaptation under limited data, while meta-learning achieves the highest accuracy when sparse calibration labels are available. Overall, our self-supervised test-time adaptation methods reach up to 82% inter-session accuracy, significantly improving upon prior approaches while maintaining resource-efficient operation. These results demonstrate that lightweight test-time adaptation can enable robust, long-term EMG decoding for wearable or prosthetic applications.

Biosignals collected from wearable devices are widely utilized in healthcare applications. Machine learning models used in these applications often rely on features extracted from biosignals due to their effectiveness, lower data dimensionality, and wide compatibility across various model architectures. However, existing feature extraction methods often lack task-specific contextual knowledge, struggle to identify optimal features in high-dimensional combinatorial feature space, and are prone to automated code generation and execution errors. In this paper, we propose DeepFeature, the first LLM-empowered, context-aware feature generation framework for wearable biosignals. DeepFeature introduces a multi-source feature generation mechanism that integrates the inherent ability of LLMs, expert knowledge and inter-feature interactions. It also employs an iterative feature refinement process that uses feature assessment-based feedback for feature re-selection. Additionally, DeepFeature utilizes a robust multi-layer filtering and verification approach for feature description-to-code translation to ensure that the feature extraction functions run without crashing. Experimental evaluation results show that DeepFeature achieves the highest average AUROC across eight tasks under both sample-level and subject-level settings, outperforming the best baselines by 4.60% and 4.61%, respectively. DeepFeature achieves the most pronounced gains on the PPG-BP tasks, while remaining competitive with the best-performing baselines on Epilepsy, WESAD, and our self-collected SEN dataset.

In this paper, a learning framework is introduced which incorporates principles of probabilistic inference, variational optimization, and geometry-preserving operations inspired by quantum transformations. The central innovation of this quantum-inspired variational convolution (QiVC) lies in its quantum-inspired rotated ensemble (QiRE) mechanism. QiRE performs differentiable low-dimensional subspace rotations of convolutional weights. By drawing a mathematical analogy from unitary evolution, this approach enables structured uncertainty modeling that respects the intrinsic geometry of the parameter space. To demonstrate its practical potential, the concept is instantiated in a QiVC-based convolutional network (QiVC-Net) and evaluated in the context of biosignal classification, focusing on phonocardiogram (PCG) recordings. The proposed QiVC-Net integrates an architecture in which the QiVC layer does not introduce additional parameters, instead performing an ensemble rotation of the convolutional weights through a structured mechanism ensuring robustness without added highly computational burden. Experiments on two benchmark datasets, PhysioNet CinC 2016 and PhysioNet CirCor DigiScope 2022, show that QiVC-Net achieves state-of-the-art performance, reaching accuracies of 97.84% and 97.89%, respectively. These findings highlight the versatility of the QiVC framework and its promise for advancing uncertainty-aware modeling in real-world biomedical signal analysis. The implementation of the QiVConv layer is available in GitHub for public use.

Earth s gravity fundamentally shapes human behaviour. The brain encodes this force as an internal model of gravity, enabling the prediction and interpretation of gravitational effects during perception and action. Understanding how this model adapts to altered gravity is critical for predicting human performance in spaceflight. We present a computational framework for modelling neurophysiological adaptation across diverse gravitational environments. The framework has two components trained on open-access data from altered-gravity studies, particularly parabolic flights. The first component (CorticalG) employs a lightweight multilayer perceptron neural network to predict gravity-dependent changes in EEG frequency bands, estimating cortical state under different gravitational loads. The second component (PhysioG) uses independent Gaussian process models to capture broader physiological responses, including heart rate variability, electrodermal activity, and motor control. To complement the quantitative modelling, we simulated subjective experience across gravitational environments using the Large Language Model (LLM) Claude 3.5 Sonnet. Physiological outputs prompted the model to generate narratives describing alertness, bodily awareness, and cognitive state across zero gravity, partial gravity of the Moon and Mars, and hypergravity. This framework provides a novel approach for investigating human adaptation to spaceflight. It offers a predictive tool to assess performance and resilience, supporting the design of future space exploration missions.

Photoplethysmography (PPG) is widely used in wearable health monitoring, but its reliability is often degraded by noise and motion artifacts, limiting downstream applications such as heart rate (HR) estimation. This paper presents a deep learning framework for PPG denoising with an emphasis on preserving physiological information. In this framework, we propose DPNet, a Mamba-based denoising backbone designed for effective temporal modeling. To further enhance denoising performance, the framework also incorporates a scale-invariant signal-to-distortion ratio (SI-SDR) loss to promote waveform fidelity and an auxiliary HR predictor (HRP) that provides physiological consistency through HR-based supervision. Experiments on the BIDMC dataset show that our method achieves strong robustness against both synthetic noise and real-world motion artifacts, outperforming conventional filtering and existing neural models. Our method can effectively restore PPG signals while maintaining HR accuracy, highlighting the complementary roles of SI-SDR loss and HR-guided supervision. These results demonstrate the potential of our approach for practical deployment in wearable healthcare systems.

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, accounting for approximately 17.9 million deaths each year. Early detection is critical, creating a demand for accurate and inexpensive pre-screening methods. Deep learning has recently been applied to classify abnormal heart sounds indicative of CVDs using synchronised phonocardiogram (PCG) and electrocardiogram (ECG) signals, as well as multichannel PCG (mPCG). However, state-of-the-art architectures remain underutilised due to the limited availability of synchronised and multichannel datasets. Augmented datasets and pre-trained models provide a pathway to overcome these limitations, enabling transformer-based architectures to be trained effectively. This work combines traditional signal processing with denoising diffusion models, WaveGrad and DiffWave, to create an augmented dataset to fine-tune a Wav2Vec 2.0-based classifier on multimodal and multichannel heart sound datasets. The approach achieves state-of-the-art performance. On the Computing in Cardiology (CinC) 2016 dataset of single channel PCG, accuracy, unweighted average recall (UAR), sensitivity, specificity and Matthew's correlation coefficient (MCC) reach 92.48%, 93.05%, 93.63%, 92.48%, 94.93% and 0.8283, respectively. Using the synchronised PCG and ECG signals of the training-a dataset from CinC, 93.14%, 92.21%, 94.35%, 90.10%, 95.12% and 0.8380 are achieved for accuracy, UAR, sensitivity, specificity and MCC, respectively. Using a wearable vest dataset consisting of mPCG data, the model achieves 77.13% accuracy, 74.25% UAR, 86.47% sensitivity, 62.04% specificity, and 0.5082 MCC. These results demonstrate the effectiveness of transformer-based models for CVD detection when supported by augmented datasets, highlighting their potential to advance multimodal and multichannel heart sound classification.

Sleep stage classification is critical for diagnosing and managing disorders like sleep apnea and insomnia. However, conventional methods like polysomnography are costly and impractical for long-term, home-based monitoring. This study presents an energy-efficient approach for detecting four sleep stages (wake, rapid eye movement (REM), light sleep, deep sleep) using a single-lead electrocardiogram (ECG) signal. We evaluate various machine learning and deep learning models, introducing two windowing strategies: (1) a 5-minute window with 30-second steps for machine learning and (2) a 30-second window with 10-second steps for deep learning, enabling 10-second temporal resolution for real-time predictions. While deep learning models like MobileNet-v1 achieve high accuracy (92%) and F1-score (91%), their energy demands make them unsuitable for wearables. To address this, we design SleepLiteCNN, optimized for ECG-based sleep staging, achieving 89% accuracy and 89% F1-score while minimizing energy use. Applying 8-bit quantization further reduces energy consumption to 5.48 microJ per inference, with 90% accuracy and F1-score. Additionally, field-programmable gate array (FPGA) deployment shows significant reductions in resource usage. This approach provides a practical, energy-efficient solution for continuous ECG-based sleep monitoring in resource-constrained wearable devices.

Teleoperation systems must be aware of the human's workload during missions to maintain operator performance. Prior work employed wearable physiological sensor response metrics to estimate current human workload; however, these estimates only enable robots to respond to under- or overload conditions reactively. Current human workload prediction approaches are limited to very short prediction horizons and fail to investigate variable lag horizons' impact on those predictions. This manuscript investigates physiological sensor driven human workload prediction focusing on the impact of lag horizons on both univariate and multivariate time series forecasting models, with longer prediction horizons than the workload prediction state-of-the-art (i.e., > 30 seconds using Long Short-Term Memory networks). Models were trained using data from a 64 participant non-sedentary supervisory environment NASA Multi-Attribute Task Battery-II human subjects evaluation. A key finding is that univariate workload predictions required 240 second lag horizons, whereas multivariate workload predictions sufficed with 120 second lag horizons. This finding indicates additional workload components reduce lag horizon requirements, enabling more efficient models with longer prediction horizons.

Mental health problems such as stress, anxiety, and depression affect millions of people worldwide. These conditions are usually assessed using questionnaires, which rely on how people describe their own feelings. In this study, we explore whether a wearable device can help measure mental health using physical signals from the body. The device records small changes in blood flow and tissue activity from the fingertip. We collected data from 132 adults across 19 countries and compared these signals with mental health questionnaire results. We found that patterns in blood flow and tissue activity are linked to stress-related symptoms. This approach may help develop new tools for simple, non-invasive mental health monitoring in everyday life. Code and datasets are publicly available: https://github.com/leduckhai/Wearable_LDF-FS

This study employs cutting-edge wearable monitoring technology to conduct high-precision, high-temporal-resolution (1-second interval) cognitive load assessment on electroencephalogram (EEG) data from the FP1 channel and heart rate variability (HRV) data of secondary vocational students. By jointly analyzing these two critical physiological indicators, the research delves into their application value in assessing cognitive load among secondary vocational students and their utility across various tasks. The study designed two experiments to validate the efficacy of the proposed approach: Initially, a random forest classification model, developed using the N-BACK task, enabled the precise decoding of physiological signal characteristics in secondary vocational students under different levels of cognitive load, achieving a classification accuracy of 97%. Subsequently, this classification model was applied in a cross-task experiment involving the National Computer Rank Examination (Level-1), demonstrating the method's significant applicability and cross-task transferability in diverse learning contexts. Conducted with high portability, this research holds substantial theoretical and practical significance for optimizing teaching resource allocation in secondary vocational education, as well as for cognitive load assessment methods and monitoring. Currently, the research findings are undergoing trial implementation in the school.

Purpose: Uncertainty Quantification (UQ) has gained traction in an attempt to improve the interpretability and robustness of machine learning predictions. Specifically (medical) biosignals such as electroencephalography (EEG), electrocardiography (ECG), electrooculography (EOG), and electromyography (EMG) could benefit from good UQ, since these suffer from a poor signal-to-noise ratio, and good human interpretability is pivotal for medical applications. To determine how uncertainty estimation can be used for biosignal tasks, we investigate current methods, use cases, applications, evaluations, and uncertainty measures. Methods: In this paper, we systematically review the state of the art of applying Uncertainty Quantification to Machine Learning tasks in the biosignal domain. All works from Web of Science, Scopus, IEEE XPlore and PsycINFO that discuss uncertainty in Machine Learning on one of the aforementioned biosignals is included. Results: We present various methods, shortcomings, uncertainty measures and theoretical frameworks that currently exist in this application domain based on the 53 reviewed papers and related literature. We address misconceptions in the field, provide recommendations for future work, and discuss gaps in the literature in relation to diagnostic implementations as well as control for prostheses or brain-computer interfaces. Conclusion: Overall it can be concluded that promising UQ methods are available, but that research is needed on how people and systems may interact with an uncertainty-model in a (clinical) environment.

We present our submission to the EgoProactive track of the ECCV 2026 Wearable AI Challenge, which ranked first in the large-model division and second in the <=2B division. The task requires a wearable assistant to decide after each eight-second segment of egocentric video whether to intervene or remain silent. Our approach has two main components. First, we reformulate intervention timing as single-token classification. Rather than generating either $interrupt$<utterance> or $silent$, the model predicts yes or no, and we derive the decision from the renormalised probabilities of these two tokens. This formulation improved macro-F1 by 0.249 and G-mean by 0.30 over free-form generation. Second, because labelled data were limited to the released validation set, we generated additional supervision using a tool-calling video agent that inspects each clip and assigns intervention timestamps. A narration-only alternative was four times larger and ten times cheaper, but transferred worse than supervision from an unrelated real corpus, suggesting that visual grounding is more important than annotation volume for this task.

Respiratory activity is a direct and interpretable physiological channel for wearable stress and affective-state recognition, yet many studies emphasize classification accuracy without identifying which respiratory properties separate different states. Using the chest respiratory channel of the WESAD dataset, we analyze 60 s windows under leave-one-subject-out validation and combine two complementary branches: compact raw-signal one-dimensional convolutional neural networks (1D-CNNs) and physically grouped handcrafted respiratory signatures. The primary task is stress versus non-stress detection, while baseline, stress, amusement, and meditation are additionally analyzed in a one-vs-rest setting to reveal state-specific respiratory markers. The feature space is organized into respiratory timing, breath-to-breath variability, waveform statistics, spectral/time-frequency descriptors, and autocorrelation/nonlinear predictability descriptors, with the raw 60 s signal treated as a sixth representation for the CNN branch. We introduce autocorrelation transition lags (Zpm/Zmp) as interpretable markers of respiratory correlation scale and separately evaluate exploratory forecast-error-growth/Lyapunov-like descriptors. In the final CNN refit setting, the raw-signal model achieved the strongest stress-vs-rest performance (accuracy 96.72%, macro-F1 95.30%, MCC 90.61%). In contrast, compact feature models were stronger for baseline (MCC 65.34%), amusement (MCC 35.69%), and especially meditation (MCC 88.65%). Strict nested reanalysis of the auxiliary Top-20 stress search yielded mean MCC=82.29% versus 85.45% originally, indicating modest selection optimism. These results show that CNNs are most useful for the practical stress detector, whereas interpretable respiratory signatures provide stronger and more physiologically transparent state-specific markers for several non-stress conditions.

The scarcity of temporally aligned pre-event physiological data limits the study of stroke risk states before documented clinical recognition. We focus on patients who experienced stroke during hospitalization while undergoing continuous monitoring, enabling retrospective analysis of pre-anchor photoplethysmography (PPG). Using MIMIC-III and MC-MED, an LLM-assisted pipeline generated candidate stroke anchors from unstructured notes. All retained anchors underwent physician adjudication, and a stratified 100-case double-review audit showed 95.0% candidate-to-adjudicated agreement within +/-15 min. We identified 176 MIMIC-III patients and 154 MC-MED patients with eligible synchronized pre-anchor PPG. A fixed 17-channel hemodynamic representation and ResNet-1D classifier were evaluated using patient-level five-fold internal validation and frozen external testing. At validation-selected operating points, F1-scores were 0.7956, 0.8759, and 0.9406 for 4-, 5-, and 6-hour horizons in MIMIC-III and 0.9256, 0.9595, and 0.9888 in MC-MED; the corresponding threshold-free AUCs ranged from 0.6124 to 0.7079. The PPG model achieved higher F1 than four non-waveform clinical and structured-EHR comparators in all six cohort-horizon settings. On high-risk non-stroke controls, window-level false-positive rates ranged from 0.1371 to 0.2938 and decreased to 0.0183-0.1739 after persistence aggregation. These retrospective findings support measurable pre-anchor PPG structure, but do not establish biological stroke onset, a calibrated bedside alarm, or a clinically validated prediction lead time.

We describe our entry to the EgoLongQA track of the Wearable-AI Challenge in ECCV 2026, which placed first in the <=2B parameter division with 0.8279 on the held-out test set. Our system is a single 2B vision-language model that answers multiple-choice questions about ten-minute egocentric videos in one greedy forward pass; It is obtained by distilling the junior perception module of a tool-using agentic pipeline, not the agent itself into a small student, using teacher traces filtered to those that answered correctly. it reaches 89% of the accuracy of the large agentic pipeline using 1.1% of its parameters. This raises a 27.1% base model to 81.4% on our held-out questions. The 2B backbone has 2.2132B parameters and therefore over the divisional limit, to make the entry admissable we prune the multilingual embedding table from 248,320 to 143,469 rows, reaching 1.9985B with provably identical logits on retained rows.