Unsupervised Domain Adaptation

Also known as UDA

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16 papers in the last four weeks, up 78% on the four weeks before. 0.2% of all new papers.

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Latest papers 111

Jun 19, 2026cs.CV

$μ$ Match: Foundation Models for Semi-supervised Learning and Domain Adaptation in EM

Vision foundation models have substantially advanced computer vision, enabling state-of-the-art performance in zero- and few-shot settings. They have been successfully applied to biomedical imaging tasks ranging from organ segmentation in computed tomography to cell segmentation in light microscopy. Electron microscopy (EM) is a central modality for analyzing cellular ultrastructure due to its nanometer-scale resolution. However, the application of foundation models in EM has so far been limited to specific organelles, such as mitochondria, largely due to the diversity of segmentation tasks and the scarcity of comprehensively annotated data. As a result, EM segmentation still predominantly relies on supervised learning, requiring extensive manual annotation and limiting ultrastructural analysis. To address this gap, we propose

μ

Match, a framework for semi-supervised learning and domain adaptation that leverages foundation models. We implement state-of-the-art student-teacher-based methods and evaluate multiple foundation models (SAM, SAM2,

μ

SAM, DINOv2/v3) on challenging EM tasks, including mitochondrion, nucleus, and neurite segmentation. Our results demonstrate consistent improvements over strong baselines and highlight a path toward substantially reducing the annotation effort in EM.

Marei Freitag, Olesia Korchevaia, Luca Freckmann +2

Life and Medical Sciences Institute (LIMES), University of Bonn, Germany · Institute of Computer Science, Georg-August-University Göttingen, Germany

Unsupervised Domain Adaptation Vision Foundation Model Adaptation Semi-Supervised Medical Image Segmentation Microscopy Image Analysis

Jun 19, 2026cs.LG

One Size does not Fit All: Heterogeneous Latent Space Alignment for Unsupervised Domain Adaptation

Domain shift remains a major obstacle to the reliable deployment of machine learning models in high-stakes environments such as healthcare. While Domain adaptation aims to mitigate these effects, existing approaches suffer from limited expressiveness of latent representations and a reliance on handcrafted, static augmentations. In this work, we address these limitations by proposing a novel deep learning architecture for Unsupervised Domain Adaptation (UDA), specifically optimized for medical image segmentation. Our framework, ADualVUOT, integrates a dual-encoder Variational Autoencoder (VAE) with Continuous Normalizing Flows (CNFs) to increase modeling flexibility and posterior expressiveness. To achieve domain alignment, we leverage Unbalanced Optimal Transport (UOT) through the Gaussian-Gromov-Wasserstein (GGW) distance, which handles structural and topological discrepancies between domains. Furthermore, we incorporate an adversarial augmentation scheme to synthesize worst-case compositions, thus enhancing model robustness. Extensive experiments on medical imaging benchmarks show significant gains over prior OT-based approaches.

Evangelia Koskinioti, Yi Shen, Georgios Stamou +1

Department of Electrical and Computer Engineering, Duke University, NC, USA · Department of Mechanical Engineering, Duke University, NC, USA · Department of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece.

Unsupervised Domain Adaptation Domain Adaptation Medical Image Segmentation

Jun 19, 2026cs.CV

Unsupervised Domain Adaptation for Sim-to-Real Object Pose Estimation with Contrastive Alignment and Pseudo-Label Refinement

Unsupervised domain adaptation (UDA) enables robust transfer of knowledge from simulated to real environments while exploiting a subset of unlabeled target data to improve real-world performance. Existing UDA methods for Object pose estimation often rely on global feature matching, multi-stage larger frameworks, or image translation pipelines, which tend to overlook the pose-specific information embedded in feature representations. To bridge this limitation, we introduce CAPLR that targets the adaptation of pose-sensitive features in localized regions, ensuring that domain alignment preserves the geometric cues essential for accurate pose estimation. CAPLR achieves UDA with three key components: (1) Efficient Cross-Domain Pairing strategy leveraging intermediate features to identify pose similar image pairs across domains without supervision; (2) Contrastive Alignment to perform feature alignment at localised regions in both intermediate and task-specific representations; and (3) Consistency-Based Pseudo-Label Refinement to improve reliability by encouraging stable target predictions. Extensive experiments demonstrate that CAPLR achieves state-of-the-art performance across multiple well-known object pose estimation benchmarks featuring diverse and challenging scenarios.

Nidhal Eddine Chenni, Arunkumar Rathinam, Djamila Aouada

SnT, University of Luxembourg

Synthetic-to-Real Domain Adaptation Unsupervised Domain Adaptation Object Pose Estimation

Jun 18, 2026cs.CV

Toward Parking Spot Occupancy Recognition: A Self-Supervised Approach

As urban areas expand, automatic monitoring of parking lots becomes essential for efficient and sustainable cities. This work proposes a self-supervised approach for parking spot occupancy recognition that requires no labeled samples from the target parking lot. Building upon a self-supervised transfer learning fine-tuning protocol, the proposed training strategy consists of two self-supervised stages: first on unlabeled generic data and then on unlabeled target-specific data, followed by supervised fine-tuning using only generic parking lot labels. We adopt SimCLR with a ResNet-50 encoder and evaluate the method under a leave-one-out cross-environment protocol on three public datasets: PKLot, CNRPark-EXT, and PLds. We also introduce a two-stage deployment strategy in which a Strong General Model is initially deployed, followed by a Specialized Model that incorporates unlabeled images collected during the first N days of deployment in a self-supervised manner. Experimental results show that the Strong General Model alone outperforms supervised and self-supervised baselines, achieving an average accuracy of 97.2%, which further improves to 97.8% with the proposed two-stage strategy. These results demonstrate that self-supervised learning enables a scalable and labelefficient solution for real-world parking occupancy monitoring. Our trained models and source code are publicly available at https://github.com/LoanMaikon/Parking-Spot-Occupancy-Recognition.

Luan Marko Kujavski, Rayson Laroca, Paulo Lisboa de Almeida

Federal University of Paran´a, Curitiba, Brazil · Pontifical Catholic University of Paran´a, Curitiba, Brazil

Unsupervised Domain Adaptation Self-Supervised Learning Intelligent Transportation Systems

Jun 11, 2026cs.CV

A Multi-Modal Framework with Cross-Subject Pseudo-Labeling and Semantic Alignment for Micro-Gesture Recognition

Micro-gestures (MGs) are spontaneous and subtle body movements that frequently convey hidden human emotions. Recognizing MGs in untrimmed videos remains highly challenging due to their extremely low signal-to-noise ratio, severe long-tailed class distribution, and the inherent domain shift encountered in cross-subject evaluation scenarios. In this paper, we propose a comprehensive multi-modal framework for Track 1 of the 4th MiGA-IJCAI Challenge. To capture fine-grained representations, we design a saliency-guided multi-modal extraction pipeline integrating 68-keypoint skeleton joint coordinates, 3D heatmap volumes, and high-resolution RGB visual features. We introduce a gentle square-root smoothed weighting mechanism paired with an Orthogonal Semantic Embedding Loss to protect tail classes without compromising overall recognition capabilities. More importantly, to bridge the cross-subject generalization gap, we propose a Cross-Modal Pseudo-Labeling (CMPL) strategy for unsupervised domain adaptation, which significantly boosts single-modal robustness. A temperature-scaled soft-voting mechanism is finally utilized to alleviate overconfidence during late fusion. Extensive experiments demonstrate that our framework achieves a competitive F1-score of 68.13%, securing the 4th place.

Haoran Zhang, Haokun Zhang, Pengyu Liu +3

School of Computer Science and Information Engineering, Hefei University of Technology (HFUT), Hefei, China · School of Computer Science, University of Auckland(UOA), Auckland, New Zealand

Unsupervised Domain Adaptation Cross-Modal Alignment Gesture Recognition Multimodal Fusion

Jun 10, 2026cs.CV

Bridging Day and Night: Unsupervised Cross-Domain Re-Identification with Synergistic Prompt and Prototype Learning

Cross-domain day-night re-identification (ReID) is fundamentally challenged by the substantial visual appearance discrepancies between daytime and nighttime scenes. Existing fully supervised methods rely heavily on labor-intensive annotations, which are costly and exhibit limited generalization across domains. In this work, we investigate unsupervised day-night ReID and propose a novel framework that synergistically combines prompt learning and prototype-based representation learning to associate identities across domains without requiring manual labels. Our approach follows a progressive two-stage training strategy. In the first stage, we exploit the vision-language model to generate instance-specific textual prompts in an annotation-free manner. We employ an instance-level alignment mechanism to embed visual features and textual prompts into a unified semantic space, aligning unlabeled day/night images with learnable prompts via instance-aware dynamic-bias adaptation. In the second stage, we construct domain-specific prototype memory banks and introduce two complementary modules: i) an intra-domain identity association module to enhance feature discriminability within each domain, and ii) a cross-domain prototype matching module to reliably identify positive and negative prototype pairs, thereby establishing robust identity correspondences across day and night. Extensive experiments on public benchmarks validate the effectiveness of our method. Under the unsupervised setting, our framework attains Rank-1 accuracy comparable to state-of-the-art fully supervised methods.

Jiyang Xu, Rui Liu, Hang Dai

School of Computer Science, Wuhan University, Wuhan, China

Unsupervised Domain Adaptation Prototype Learning Visual Prompt Learning Person Re-Identification

Jun 6, 2026cs.CV

One Stone, Three Birds: Self-adaptive Optimal Transport for Multi-VLM Selection, Adaptation, and Ensembling

Vision-language models (VLMs) enable visual recognition from semantic class descriptions, which makes them attractive when target annotations are scarce or unavailable. Most deployment pipelines, however, first choose a single VLM and then adapt that model to the unlabeled target set. This single-backbone paradigm hides a critical assumption: the selected VLM is already compatible with the target domain. In realistic cross-domain deployment, several general-purpose and domain-specialized VLMs may be plausible, yet no instance-level target labels are available to identify the reliable ones. Deployment therefore requires a coupled solution for model selection, target adaptation, and prediction integration. We revisit this problem from a system-level multi-VLM perspective. Our central observation is that the three decisions above depend on the same latent object: a trustworthy sample-class structure in the target set. Different VLMs may encode different transfer biases and produce conflicting predictions, but their outputs can still provide complementary evidence for estimating this structure. We propose One Stone, Three Birds, a training-free framework based on self-adaptive optimal transport. Given a pool of frozen candidate VLMs, OSTB estimates a consensus sample-to-class transport plan without updating VLM parameters. The learned transport structure is then reused for all deployment objectives: model selection is performed by ranking the combined semantic and visual reliability induced by the consensus plan; target adaptation is obtained by fitting transport-conditioned visual classifiers; and ensembling is implemented through reliability-aware probabilistic integration. Extensive experiments on natural-image, remote-sensing, and medical-pathology benchmarks show that OSTB improves model ranking, adaptation stability, and ensemble robustness under heterogeneous candidate pools.

Qiyu Xu, Zhanxuan Hu, Yu Duan +4

School of Computer Science and Technology and the Ministry of Education Key Lab for Intelligent Networks and Network Security, Xi’an Jiaotong University, Xi’an, Shaanxi 710049, China · School of Information Science and Technology, Yunnan Normal University, Chenggong, Kunming, Yunnan 650500, China · School of Telecommunications Engineering, Xidian University, Xi’an 710071, China +1

Vision-Language Models Unsupervised Domain Adaptation VLM Adaptation

Jun 3, 2026cs.CV

Who Needs Labels? Adapting Vision Foundation Models With the Metadata You Already Have

We propose a label-free approach to adapt powerful but generic vision foundation models to specialized scientific domains. Standard supervised fine-tuning is often ill-suited to these settings: labels are scarce, and task-specific training can collapse the model's generality and hurt robustness. We instead leverage metadata to adapt representations to new domains in a self-supervised manner. Our method, FINO, combines a standard self-supervised objective with flexible metadata guidance that handles both highly granular discrete metadata and continuous metadata. It encourages the representation to preserve informative factors while suppressing spurious ones. Across subcellular fluorescence microscopy, Earth observation, wildlife monitoring, and medical imaging, FINO consistently outperforms standard unsupervised domain adaptation and fully supervised adaptation. It also exceeds highly-specialized domain-specific state of the art, while using no task labels for backbone adaptation and only lightweight probes for supervision.

Elouan Gardès, Seung Eun Yi, Kartik Ahuja +6

Meta FAIR, Paris · Columbia University, New York · LIGM, CNRS, Gustave Eiffel, ENPC, IP Paris

Unsupervised Domain Adaptation Domain Adaptation Vision Foundation Model Adaptation Self-Supervised Visual Representation Learning

Jun 3, 2026cs.LG

Towards Accurate Model Selection in Deep Unsupervised Domain Adaptation

Deep unsupervised domain adaptation (Deep UDA) methods successfully leverage rich labeled data in a source domain to boost the performance on related but unlabeled data in a target domain. However, algorithm comparison is cumbersome in Deep UDA due to the absence of accurate and standardized model selection method, posing an obstacle to further advances in the field. Existing model selection methods for Deep UDA are either highly biased, restricted, unstable, or even controversial (requiring labeled target data). To this end, we propose \textit{Deep Embedded Validation} (\textbf{DEV}), which embeds adapted feature representation into the validation procedure to obtain unbiased estimation of the target risk with bounded variance. The variance is further reduced by the technique of control variate. The efficacy of the method has been justified both theoretically and empirically.

Kaichao You, Ximei Wang, Mingsheng Long +1

School of Software, Tsinghua University, Beijing, China · BNRist, Research Center for Big Data, Tsinghua University, Beijing, China · University of California, Berkeley, USA

Unsupervised Domain Adaptation

Jun 2, 2026cs.LG

ADAPTOOD: Uncertainty-Aware Fine-Tuning for Out-of-Distribution ECG Time Series Models

Data samples used for training often differ from those encountered during fine-tuning and deployment, and while ML models show promise, their performance remains limited when only small annotated datasets are available. Performance often degrades under distribution shifts caused by diverse sensors, populations, and application settings. Although pre-training helps, models frequently encounter out-of-distribution (OOD) data in real-world settings, leading to reduced robustness. Existing adaptation methods usually assume fixed distribution shifts and struggle when multiple types or severities occur. In particular, they overlook shift severity, for example treating adaptation to a large familiar dataset the same as adaptation to a small dataset with a new task, which limits generalisation. To address this, we propose ADAPTOOD, a novel framework that leverages data uncertainty to quantify distribution shift severity and guide fine-tuning for time series. This uncertainty measures how strongly samples from the target deployment distribution deviate from the pre-training distribution, providing a direct signal of OOD severity. Our framework combines this uncertainty with low-rank model updates and adaptive hyperparameter optimisation to improve adaptation. We show that ADAPTOOD achieves up to 7% higher accuracy and 12.9% higher precision than existing methods in OOD tasks, maintaining strong performance as distribution shift severity increases.

Sotirios Vavaroutas, Yu Yvonne Wu, Ali Etemad +1

University of Cambridge, UK · Dartmouth College, USA · Queen’s University, Canada

Distribution Shift Robustness Unsupervised Domain Adaptation OOD Generalization Electrocardiogram Classification

Jun 1, 2026cs.CV

Unsupervised Collaborative Domain Adaptation for Driving Scene Parsing

Reliable driving scene parsing is a fundamental capability for autonomous vehicles operating in open and dynamic driving environments. However, adapting perception models to new deployment domains remains challenging because pixel-level annotations are expensive to obtain, while source-domain data are often inaccessible due to privacy, security, or ownership constraints. Existing source-free unsupervised domain adaptation methods typically rely on a single pre-trained source model, which makes the adapted perception system vulnerable to source-specific biases and limits its robustness under diverse road layouts, illumination conditions, weather patterns, and traffic conditions. This article presents an unsupervised collaborative domain adaptation (UCDA) framework for driving scene parsing in a source-free setting, which transfers complementary knowledge from multiple pre-trained source models to a unified target model without accessing any original source samples. To compare predictions from independently trained models, UCDA constructs a class-level prototype memory bank and estimates cross-model prediction reliability through prototype similarity, reducing the effect of inconsistent confidence scales across source models. Based on the resulting complementary supervision, UCDA adopts a two-stage transfer strategy: multiple source models are first refined on unlabeled target-domain driving data through collaborative optimization with positive and negative consistency constraints, and their validated expertise is then distilled into a single deployable target model. Comprehensive evaluations on public driving-scene datasets and real-world data collected from an autonomous vehicle platform demonstrate that UCDA effectively consolidates complementary multi-source knowledge, improving target-domain scene parsing reliability and generalization across diverse driving environments.

Jiahe Fan, Shaolong Shu, Mingjian Sun +4

College of Electronic and Information Engineering, Tongji University, Shanghai 201804, China · Department of Control Science and Engineering, the Harbin Institute of Technology, Harbin, Heilongjiang, 150001, China · School of Computer Science and Technology, Tongji University, Shanghai, 201804, China +2

Multi-Source Domain Adaptation Source-Free Domain Adaptation Unsupervised Domain Adaptation Domain Adaptation Autonomous Driving Perception Semantic Segmentation

May 29, 2026cs.HC

UF-AMA: A unified framework for cross-domain emotion recognition via adaptive multimodal alignment

In recent years, emotion recognition based on physiological signals such as electroencephalogram (EEG) has gained considerable attention, as internal physiological data offer greater objectivity and reliability compared to external behavioral data like facial expressions. However, due to distribution shifts caused by individual and contextual differences, along with variations in sample quality across modalities, constructing a cross-domain multimodal emotion recognition model with high generalization and robustness remains a key challenge. In this study, we propose a Unified Framework with Adaptive Multimodal Alignment (UF-AMA) to address cross-subject and cross-session emotion recognition using multimodal physiological signals. First, we construct a cross-modal feature fusion network comprising Transformer encoders and multi-head cross-attention modules, enabling the deep integration of EEG signals and eye-tracking data. Subsequently, we introduce a confidence-aware screening mechanism that dynamically assesses the predictive reliability of each modality branch on target domain samples, partitions samples into different quality subsets, and accordingly applies global consistency alignment and cross-modal distillation. Finally, we propose a multi-level domain adaptation framework that jointly optimizes the marginal and conditional distributions of both local modality-specific and global fusion features, thereby reducing cross-domain distribution shifts at multiple granularities. Extensive experiments on the SEED and SEED-IV datasets demonstrate that UF-AMA achieves state-of-the-art (SOTA) performance in both cross-subject and cross-session tasks. The source code is available at: https://github.com/BetterCoderLab/UF-AMA.

Zheng Wang, Shuo Wang, Junhong Wang

Institute of Advanced Technology, University of Science and Technology of China, Hefei, 230026, China · Department of Electronic Engineering and Information Science, University of Science and Technology of China, Hefei, 230026, China · Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, 230026, China

Unsupervised Domain Adaptation Multimodal Emotion Recognition EEG Emotion Recognition Multimodal Fusion Emotion Recognition

May 29, 2026stat.ML

Entropic Projection Alignment: Estimating, Explaining, and Improving Model Performance Under Distribution Shift

We propose a unified framework for addressing three key challenges of distribution shift: (1) estimating a model's performance on an unlabeled target domain, (2) explaining the shift by identifying the features responsible, and (3) improving the target domain performance. Our method, Entropic Projection Alignment (EPA), aligns the source distribution to the target by matching carefully selected moments while simultaneously minimising the KL divergence from the source. This formulation yields a unique closed-form solution for importance weights, achieving robustness through implicit variance control. Drawing on domain adaptation theory, we establish that moment matching is sufficient for reliable estimation and adaptation, avoiding the need for full density ratio recovery. Extensive experiments, together with strong theoretical guarantees, demonstrate that EPA consistently outperforms state-of-the-art baselines while offering substantial computational efficiency.

Salim I. Amoukou, Emanuele Albini, Tom Bewley +2

J.P. Morgan AI Research

Distribution Shift Robustness Unsupervised Domain Adaptation Distribution Shift Importance Weighting

May 27, 2026cs.CV

Robust Cross-Domain Generalization Using Unlabeled Target Data with Source-Domain Supervision

It is often desirable to generalize medical imaging AI models trained with dense annotations to data acquired from different ultrasound scanners or clinical sites; however, retraining these models with new annotations is often difficult and costly. We examine this challenge in pediatric wrist fracture assessment using point-of-care ultrasound (POCUS), where fractures are common and can be effectively triaged via ultrasound. AI has shown radiologist-level performance for fracture detection, often aided by high-quality bony structure segmentation. However, due to significant domain shifts, models perform poorly on data from other centers or probes, and obtaining segmentation labels across devices is impractical due to manual annotation effort and data privacy concerns. To address this, we propose a target-informed self-supervised pretraining and model-ensemble strategy. Specifically, our approach combines masked image modeling (MIM) and contrastive learning to learn target-domain structural representations without labels, and introduces a confidence-aware infusion head to adaptively integrate predictions. The source dataset, collected with a Philips Lumify probe, contained dense labels, while the target dataset, acquired with a TeleMED portable probe, was unlabeled. The datasets were kept strictly separate throughout the entire process. Our method used labeled source data for supervised training and leveraged target-domain pretraining to improve generalization. On 318 images from 62 pediatric POCUS videos, this approach significantly improved cross-device performance, achieving over 6% Dice improvement on the target domain versus the baseline. These results demonstrate a label-efficient and privacy-preserving approach for cross-device-robust ultrasound AI, offering a framework that can be extended to multi-center studies or federated learning setups.

Yuyue Zhou, Shrimanti Ghosh, Michael +7

Kai Yue · Department of Radiology and Diagnostic Imaging, University of Alberta, 8303 112 St NW, Edmonton, T6G 2T4, AB, Canada

Ultrasound Image Segmentation Unsupervised Domain Adaptation Cross-Dataset Generalization

May 24, 2026cs.CV

Discrepancy Minimization Improves Cross-Hospital Robustness in Digital Pathology

Pathology foundation models (PFMs) have advanced rapidly in recent years and support training classifiers for a range of histopathology tasks. However, their robustness across hospitals remains limited: performance often degrades when training a classifier on data from one hospital and evaluating it on another target hospital. We address this challenge by fine-tuning PFMs with a local maximum mean discrepancy (LMMD) objective that applies to two settings: domain adaptation, where unlabeled target-hospital data is available, and domain generalization, where target-hospital data is unavailable at all. Experiments at both the patch- and slide-level show consistent improvements across multiple PFMs and tasks.

Ben Vardi, Dana Schonberger, Yuval Friedmann +4

Reichman University, Herzliya, Israel · Institute of Pathology, Sheba Medical Center, Ramat-Gan, Israel · Technion - Israel Institute of Technology, Haifa, Israel

Computational Pathology Unsupervised Domain Adaptation Healthcare Maximum Mean Discrepancy Domain Generalization Pathology Foundation Models+1

May 24, 2026cs.CV

Trust-Aware Joint Feature-Prediction Discrepancy for Robust Domain Adaptation

Domain adaptation aims to mitigate performance degradation caused by distribution shifts between a labeled source domain and an unlabeled or sparsely labeled target domain. Most existing approaches estimate domain discrepancy either in feature space or in prediction space. However, these single-perspective strategies overlook a critical problem under domain shift: the reliability of the signals used for alignment. In practice, both learned representations and semantic predictions may become unreliable, and treating all target samples equally can lead to misleading alignment and suboptimal transfer. We introduce trust-aware domain adaptation, a principled framework that models domain discrepancy through the reliability of feature and prediction signals. Central to our approach is the Joint Feature-Prediction Discrepancy (JFPD), a unified formulation that jointly captures representation divergence and prediction divergence while weighting their contributions by sample-specific trust. Trust is quantified via two complementary mechanisms: uncertainty-aware trust, derived from prediction entropy to suppress unreliable predictions, and semantic-alignment trust, computed from prototype similarity in feature space to emphasize well-aligned representations. By prioritizing confident and semantically consistent samples while down-weighting noisy or ambiguous ones, JFPD provides a reliability-aware estimate of domain discrepancy. We further integrate JFPD into a training objective that guides adaptation toward trustworthy regions of the target domain. Experiments on standard benchmarks demonstrate that the proposed framework consistently achieves superior adaptation performance and yields discrepancy estimates that correlate with target-domain error. This work addresses, for the first time, the importance of modeling trust in the interaction between features and predictions for domain adaptation.

Xi Ding, Lei Wang, Syuan-Hao Li +1

School of Engineering and Built Environment, Griffith University, Australia

Distribution Shift Robustness Unsupervised Domain Adaptation Domain Adaptation

May 24, 2026cs.CV

DA-UCT: Self-Supervised Domain-Adaptive Ultrasound Computed Tomography for Rapid Musculoskeletal Sound Speed Reconstruction

Ultrasound computed tomography (UCT) via full waveform inversion (FWI) enables high-resolution quantitative imaging for tissue characterization and disease diagnosis. However, UCT suffers from large computational burden and severe convergence issues due to highly nonlinear optimization. Deep learning can accelerate UCT reconstruction, but supervised training requires large-scale labeled datasets difficult to obtain in vivo. To address these limitations, we propose SDA-UCT, a two-stage self-supervised domain-adaptive framework for rapid and accurate UCT imaging of musculoskeletal tissues. SDA-UCT employs an attention-enhanced network (AttUCT) pre-trained on simulation datasets and transfers to in-vivo data via physics-informed self-supervised learning, effectively bridging the simulation-to-real domain gap. A Low-Rank Adaptation (LoRA) mechanism is integrated to enable efficient adaptation across diverse clinical scenarios. Results showed that AttUCT achieved high-quality SOS reconstruction for simulated human forearm with a PSNR of 29.23 dB and SSIM of 0.928, outperforming conventional FWI and existing deep learning methods. Validated on in-vivo data, SDA-UCT successfully reconstructed SOS images revealing complex anatomical structures (skin, fat, muscle, tendon, bone and bone marrow) for human forearm, in high concordance with MRI references. The LoRA mechanism adjusting only 3% of parameters achieved comparable performance to full fine-tuning. The rapid reconstruction (5 ms per frame) enables real-time 3D visualization, achieving five-orders-of-magnitude improvement over traditional FWI. This work represents the first self-supervised domain-adaptive deep learning for rapid, high-resolution in-vivo UCT imaging, showing potential for musculoskeletal disease diagnosis.

Tianyu Liu, Heyu Ma, Aiduo Wang +6

College of Biomedical Engineering, Fudan University, Shanghai 200433, China · College of Future Information Technology, Fudan University, Shanghai 200433, China · State Key Laboratory of Integrated Chips and Systems, Fudan University, Shanghai 201203, China

Synthetic-to-Real Domain Adaptation Unsupervised Domain Adaptation Ultrasound Imaging Physics-Informed ML

May 22, 2026cs.SD

Music Transcription with (Almost) No Supervision

Competitive music transcription models require large amounts of paired audio-score data, which is scarce due to collection costs, alignment difficulty, and copyright restrictions. Meanwhile, vast quantities of unpaired audio recordings and symbolic scores are freely available but have gone unused. We adopt a cycle-consistent translation framework in which a small amount of paired data acts as a minimal anchor, unlocking the full potential of the unpaired pool. We find that: unpaired data yields surprisingly large gains, especially under limited supervision; unpaired audio contributes more than unpaired scores; incorporating unlabeled audio from a new instrument during training improves transcription for that instrument without any paired supervision. Together, these results suggest that scaling unpaired data offers a practical path toward high-quality transcription for instruments where labeled data remains scarce.

Saebyeol Shin, Chao Wan, Zhenzhen Liu +4

Cornell University, Ithaca, NY

Unsupervised Domain Adaptation Automatic Music Transcription Music Information Retrieval Semi-Supervised Learning

May 20, 2026cs.LG

Expectation Consistency Loss: Rethink Confidence Calibration under Covariate Shift

Confidence calibration for classification models is vital in safety-critical decision-making scenarios and has received extensive attention. General confidence calibration methods assume training and test data are independent and identically distributed, limiting their effectiveness under covariate shifts. Previous calibration methods under covariate shift struggle with class-wise or canonical calibrations and often rely on unstable importance weighting when density ratios are large or unbounded. Given the above limitations, this paper rethinks confidence calibration under covariate shifts. First, we derive a necessary and sufficient condition for confidence calibration under covariate shifts, named Expectation consistency condition, which reveals covariate shifts do not necessarily lead to uncalibrated confidence and provides a weaker condition for confidence calibration than global covariate distribution alignment. Then, utilizing Expectation consistency condition, this paper proposes an unsupervised domain adaptation loss to calibrate confidence of the target domain, named Expectation consistency loss (ECL), which is compatible with canonical calibration, class-wise calibration, and top-label calibration. Third, we prove that computing ECL loss has the same sample complexity as Expected Calibration Error (ECE) and provide a theoretically grounded mini-batch trainable scheme for ECL loss. Finally, we validate the effectiveness of our method on both simulated and real-world covariate shift datasets.

Jinzong Dong, Zhaohui Jiang, Bo Yang

School of Automation, Central South University, Changsha, China.

Probability Calibration Unsupervised Domain Adaptation Covariate Shift Model Calibration Uncertainty Calibration

May 19, 2026cs.CV

Return of Frustratingly Easy Unsupervised Video Domain Adaptation

Unsupervised video domain adaptation (UVDA) is a practical but under-explored problem. In this paper, we propose a frustratingly easy UVDA method, called MetaTrans. Specifically, MetaTrans adopts a concise learning objective that contains only two fundamental loss terms. Despite the simplicity of the learning objective, MetaTrans embodies an advanced UVDA idea, that is, handling the spatial and temporal divergence of cross-domain videos separately, through a subtle model architecture design. By implementing a temporal-static subtraction module, MetaTrans effectively removes spatial and temporal divergence. Extensive empirical evaluations, particularly on various cross-domain action recognition tasks, show substantial absolute adaptation performance enhancement and significantly superior relative performance gain compared with state-of-the-art UVDA baselines.

Pengfei Wei, Yiqun Sun, Zhiqiang Xu +2

1Magellan Technology Research Institute (MTRI), Japan · 2Mohamed bin Zayed University of Artificial Intelligence, UAE · 3Nanyang Technological University, Singapore.

Unsupervised Domain Adaptation Video Action Recognition

May 16, 2026cs.LG

Cross-Domain Molecular Relational Learning: Leveraging Chemical Structure-Activity Analysis

Recent advances in molecular representation integrates molecular topological and visual modalities, opening new avenues for precise Molecular Relational Learning (MRL). Existing MRL methods focus on intra-domain modeling, and their inherent domain-closed effect limits applicability to molecular science, particularly in elucidating cross-domain interaction mechanisms. Consequently, the imperative for Cross-Domain Molecular Relational Learning has become increasingly pressing. Benefiting from structure-activity analysis, we propose the Domain Adversarial Training Network with Structural-Semantic Transfer Discrepancy (DisTrans) to optimize cross-domain adaptive representation for molecular structures and visual images. 1) We employ the gradient reversal strategy based on substructure topological discrepancies between domains to learn the domain dependence of molecular structures. This strategy guides the model to adapt to the structural adjacency patterns in the target domain, generating domain-separable structural representations. 2) We apply the cross-domain representation guidance mechanism to align the functional-group semantic information between the source and target domains, learning cross-domain consistency information. The experimental results in two typical cross-domain strategies demonstrate that DisTrans outperforms 16 baseline methods, maintaining satisfactory performance even under pronounced inter-domain discrepancy.

Peiliang Zhang, Jingling Yuan, Shiqing Wu +4

Wuhan University of Technology Wuhan, Hubei, China · Hubei Key Laboratory of Transportation Internet of Things State Key Laboratory of Silicate Materials for Architectures Wuhan University of Technology Wuhan, Hubei, China · Yonsei University Seoul, Republic of Korea +3

Domain-Adversarial Learning Cross-Modal Representation Learning Unsupervised Domain Adaptation Cross-Modal Alignment Molecular Representation Learning

May 14, 2026cs.LG

TILT: Target-induced loss tilting under covariate shift

We introduce and analyze Target-Induced Loss Tilting (TILT) for unsupervised domain adaptation under covariate shift. It is based on a novel objective function that decomposes the source predictor as

f+b

, fits

f+b

on labeled source data while simultaneously penalizing the auxiliary component

b

on unlabeled target inputs. The resulting fit

f

is deployed as the final target predictor. At the population level, we show that this target-side penalty implicitly induces relative importance weighting at the population level, but in terms of an estimand

b^*_f

that is self-localized to the current error, and remains uniformly bounded for any source-target pair (even those with disjoint supports). We prove a general finite-sample oracle inequality on the excess risk, and use it to give an end-to-end guarantee for training with sparse ReLU networks. Experiments on controlled regression problems and shifted CIFAR-100 distillation show that TILT improves target-domain performance over source-only training, exact importance weighting, and relative density-ratio baselines, with a stable dependence on the regularization parameter.

Kakei Yamamoto, Martin J. Wainwright

Lab for Information and Decision Systems · Statistics and Data Science Center · EECS† +2

Unsupervised Domain Adaptation Distribution Shift Domain Adaptation Covariate Shift Importance Weighting

May 13, 2026cs.LG

Learning to Select Source Domains: Proxy-Rewarded Policy Optimization for Molecular OOD Generalization

Molecular property prediction under severe out-of-distribution (OOD) shifts remains challenging because conventional scaffold splits can retain local structural similarity between training and test molecules, while adaptation from heterogeneous source domains may cause negative transfer. We introduce SCOPE-Bench, a scaffold-cluster benchmark constructed by partitioning Bemis-Murcko scaffolds in an explicit physicochemical descriptor space, and POMA, a retrieve-compose-adapt framework for source-domain selection when target property labels are unavailable. POMA uses unlabeled target structures to retrieve labeled source scaffolds as proxy targets. A policy is trained from reductions in proxy-task mean absolute error after adaptation, and the selected source subset is then used for target adaptation with covariance alignment at the whole-molecule and BRICS-derived substructure levels. We evaluate HOMO, LUMO, and HOMO-LUMO gap prediction on QM9 using three 3D molecular backbones and 15 target-scaffold tasks. Relative to conventional scaffold splitting, prediction errors on SCOPE-Bench increase by up to 8.0-fold, with a mean increase of 5.9-fold. Relative to the supervised baseline under the strict OOD split, POMA reduces mean absolute error by up to 11.2%, with an average relative reduction of 6.2% over the nine backbone-property combinations. These results support adaptive source selection as a useful strategy for molecular prediction under strong structural distribution shifts.

Zhuohao Lin, Kun Li, Jiameng Chen +4

School of Computer Science Wuhan University Wuhan, China · College of Computer Science and Technology, Zhejiang University Hangzhou, China · School of Life Sciences and Technology, Tongji University Shanghai, 200092, China +1

Unsupervised Domain Adaptation Domain Adaptation Domain Generalization OOD Generalization Molecular Property Prediction

May 13, 2026cs.CV

HIR-ALIGN: Enhancing Hyperspectral Image Restoration via Diffusion-Based Data Generation

Hyperspectral image (HSI) restoration is crucial for reliable analysis, as real-world HSIs suffer from noise, blur, and resolution loss. However, existing models trained on source data often fail on target domains lacking clean references, a common real-world scenario. To address this, we present HIR-ALIGN, a plug-and-play target-adaptive augmentation framework that enhances HSI restoration by augmenting limited training images with synthetic data matching the target distribution, without extra clean target-domain HSI data. It has three stages: (i) proxy generation, where off-the-shelf restoration models are applied to degraded target observations to produce semantics-preserving proxy HSIs that approximate clean target-domain images; (ii) distribution-adaptive synthesis, where a blur-robust unCLIP diffusion model generates target-aligned RGBs from proxy RGBs with prompt conditioning and embedding-space noise initialization. The warp-based spectral transfer module then synthesizes HSIs by aligning each generated RGB with its proxy RGB, estimating soft patch-wise transport weights, and applying these weights and learnable local interpolation kernels to the proxy HSI; and (iii) aligned supervised finetuning, where restoration networks pretrained on the source distribution are finetuned with proxy HSIs and synthesized target-aligned HSIs, then deployed on degraded target images. We also provide theoretical analysis showing that, under stated assumptions, the proposed augmentation-based finetuning obtains a tighter target-domain restoration-risk upper bound by jointly improving target-distribution coverage and controlling spectral bias. Experiments on simulated and real datasets across denoising, super-resolution, and other restoration tasks demonstrate that HIR-ALIGN is superior to proxy-only target-adaptation baselines and outperforms representative unsupervised methods in most cases.

Li Pang, Heng Zhao, Yijia Zhang +2

Synthetic Data Augmentation Unsupervised Domain Adaptation Hyperspectral Imaging

May 12, 2026cs.CV

OmniHumanoid: Streaming Cross-Embodiment Video Generation with Paired-Free Adaptation

Cross-embodiment video generation aims to transfer motions across different humanoid embodiments, such as human-to-robot and robot-to-robot, enabling scalable data generation for embodied intelligence. A major challenge in this setting is that motion dynamics are partly transferable across embodiments, whereas appearance and morphology remain embodiment-specific. Existing approaches often entangle these factors, and many require paired data for every target embodiment, which limits scalability to new robots. We present OmniHumanoid, a framework that factorizes transferable motion learning and embodiment-specific adaptation. Our method learns a shared motion transfer model from motion-aligned paired videos spanning multiple embodiments, while adapting to a new embodiment using only unpaired videos through lightweight embodiment-specific adapters. To reduce interference between motion transfer and embodiment adaptation, we further introduce a branch-isolated attention design that separates motion conditioning from embodiment-specific modulation. In addition, we construct a synthetic cross-embodiment dataset with motion-aligned paired videos rendered across diverse humanoid assets, scenes, and viewpoints. Experiments on both synthetic and real-world benchmarks show that OmniHumanoid achieves strong motion fidelity and embodiment consistency, while enabling scalable adaptation to unseen humanoid embodiments without retraining the shared motion model.

Yiren Song, Xiyao Deng, Pei Yang +2

Show Lab, National University of Singapore

Unsupervised Domain Adaptation Streaming Video Generation Synthetic Data Generation for Robotics Video Generation Cross-Embodiment Transfer Humanoid Robotics

May 11, 2026cs.CV

MUSDA: Multi-source Multi-modality Unsupervised Domain Adaptive 3D Object Detection for Autonomous Driving

With the advancement of autonomous driving, numerous annotated multi-modality datasets have become available. This presents an opportunity to develop domain-adaptive 3D object detectors for new environments without relying on labor-intensive manual annotations. However, traditional domain adaptation methods typically focus on a single source domain or a single modality, limiting their effectiveness in multi-source, multi-modality scenarios. In this paper, we propose a novel framework for multi-source, multi-modality unsupervised domain adaptation in 3D object detection for autonomous driving. Given multiple labeled source domains and one unlabeled target domain, our framework first introduces hierarchical spatially-conditioned (HSC) domain classifiers, which jointly align features from both camera and LiDAR modalities at two distinct levels for each source-target domain pair. To effectively leverage information from multiple source domains, we construct a prototype graph between each pair of domains. Based on this, we develop a prototype graph weighted (PGW) multi-source fusion strategy to aggregate predictions from multiple source detection heads. Experimental results on three widely used 3D object detection datasets - Waymo, nuScenes, and Lyft - demonstrate that our proposed framework effectively integrates information across both modalities and source domains, consistently outperforming state-of-the-art methods.

Xiaohu Lu, Hamed Khatounabadi, Hayder Radha

Electrical and Computer Engineering Michigan State University East Lansing, USA

Multi-Source Domain Adaptation Unsupervised Domain Adaptation Camera-LiDAR Fusion Autonomous Driving Perception 3D Object Detection

May 7, 2026cs.LG

STDA-Net: Spectrogram-Based Domain Adaptation for cross-dataset Sleep Stage Classification

Accurate sleep stage classification across datasets remains challenging due to variability in EEG channel montages, sampling rates, recording environments, and subject populations. Although deep learning has shown considerable promise for automated sleep staging, most existing cross-dataset methods rely on one-dimensional EEG signal representations, whereas the use of two-dimensional spectrogram-based inputs within an unsupervised domain adaptation framework has remained largely unexplored. Here, we propose STDA-Net (Spectrogram-based Temporal Domain Adaptation Network), a framework that combines a convolutional neural network (CNN) for spectrogram-based feature extraction, a bidirectional long short-term memory (BiLSTM) module for temporal modeling of sleep dynamics, and a domain-adversarial neural network (DANN) for source-to-target feature alignment without requiring any labeled target-domain data during training. Experiments are conducted on three publicly available datasets Sleep-EDF, SHHS-1, and SHHS-2 under six cross-dataset transfer settings. Results show that the proposed framework achieves an average accuracy of 89.03% and an average macro F1-score of 87.64%, consistently outperforming existing 1D baseline methods in terms of balanced classification performance, with substantially lower variance across five independent runs, indicating improved stability and reproducibility. Overall, these findings demonstrate that 2D spectrogram-based representations, combined with temporal modeling and adversarial domain adaptation, provide a robust and competitive alternative to conventional 1D EEG inputs for cross-dataset sleep staging.

Unaza Tallal, Shruti Kshirsagar, Ankita Shukla

School of Computing, Wichita State University, 1845 N. Fairmount, Wichita, KS 67260, USA · Computer Science and Engineering Department, University of Nevada, Reno, NV, USA

Electroencephalography Sleep Stage Classification Unsupervised Domain Adaptation Time Series Classification Cross-Dataset Generalization

May 7, 2026cs.LG

Information-Preserving Domain Transfer with Unlabeled Data in Misspecified Simulation-Based Inference

Simulation-based inference (SBI) provides amortized Bayesian parameter inference from simulator-generated data without requiring explicit likelihood evaluation. Its reliability can degrade under model misspecification, where real-world observations are not well represented by the simulator used for training. Existing methods using unlabeled real-world data often align simulated and real-world data distributions, but marginal alignment alone does not directly preserve parameter-relevant information needed for posterior inference. We propose SPIN, an SBI framework with parameter-relevant information-preserving domain transfer using unlabeled, unpaired real-world observations. During training, SPIN translates labeled simulator observations toward the real-world domain and back to the simulator domain, using the original simulator labels to encourage domain transfer that preserves parameter-relevant mutual information. At test time, the learned real-to-simulator transport maps real-world observations into the simulator domain for posterior inference, without requiring real-world parameter labels or paired real--simulator observations. Across controlled synthetic and physical real-world benchmarks, SPIN improves real-world posterior inference, with the improvement becoming clearer as misspecification increases.

Joon Jang, Eunho Jeong, Kyu Sung Choi +1

Department of Biomedical Sciences, Seoul National University, Seoul, Republic of Korea · Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea · Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea +3

Synthetic-to-Real Domain Adaptation Simulation-Based Inference Unsupervised Domain Adaptation Domain Adaptation Bayesian Inference Model Misspecification

May 7, 2026cs.AI

Locality-aware Private Class Identification for Domain Adaptation with Extreme Label Shift

Domain adaptation aims to transfer knowledge from a labeled source domain to an unlabeled target domain with different distributions. In real-world scenarios, the label spaces of the two domains often have an inclusion relationship, where some classes exist only in one domain but not the other. These non-overlapping classes are referred to as private classes. Identifying private class samples and mitigating their adverse effects is critical in the literature. Existing methods rely on the assumption that shifts in private classes are large enough to be considered outliers. However, the variance within a single shared class can be significantly larger than the difference between a private class and another shared class, challenging this assumption. Consequently, private classes substantially increase the difficulty of cross-domain classification. To address these issues, based on local transportation and metric properties of optimal transport (OT), a locality-aware private class identification approach is proposed in the form of a score function on transport mass. The effectiveness of the proposed approach is theoretically proven, highlighting the score function's strong ability to distinguish between shared and private class samples. Building on this, we introduce a reliable OT-based method (ReOT) for domain adaptation under severe label shift. ReOT minimizes classification risk while learning the separated cluster structure between the identified shared classes and private classes, effectively avoiding mismatch between shared-private sample pairs, thus ensuring that important knowledge is reliably transported intra-class to mitigate class-conditional discrepancy. Furthermore, a generalization upper bound of the target risk is provided for extreme label shift scenarios, which can be minimized by ReOT. Extensive experiments on benchmarks validate the effectiveness of ReOT.

Chuan-Xian Ren, Cheng-Jun Guo, Hong Yan

School of Mathematics, Sun Yat-Sen University, Guangzhou 510275, China · Department of Electrical Engineering, City University of Hong Kong, Hong Kong, China

Label Shift Unsupervised Domain Adaptation Domain Adaptation Optimal Transport

May 6, 2026cs.LG

Order Matters: Improving Domain Adaptation by Reordering Data

Domain shift remains a key challenge in deploying machine learning models to the real world. Unsupervised domain adaptation (UDA) aims to address this by minimising domain discrepancy during training, but the discrepancy estimates suffer from high variance in stochastic settings, which can stifle the theoretical benefits of the method. This paper proposes Optimal Reordering of Data for Error-Reduced Estimation of Discrepancy (ORDERED), a novel unbiased stochastic variance reduction technique which reduces the discrepancy estimation error by optimising the order in which the training data are sampled. We consider two specific domain discrepancy losses (correlation alignment and the maximum mean discrepancy), formulate their stochastic estimation error as a function of the data sampling order, and propose a practical optimisation algorithm. Our simulations demonstrate reduced variance compared to related methods, and experiments on two domain shift image classification benchmarks show improved target domain accuracy.

Andrea Napoli, Paul White

University of Southampton, UK

Unsupervised Domain Adaptation Variance Reduction