Upper-Limb Exoskeletons

Electromyography (EMG)-driven control enables wearable robots to assist users based on their neuromuscular activity. Upper-limb exoskeletons typically rely on proportional myoelectric control (PMC), which amplifies user effort but may compromise stability at high assistance levels. EMG-driven adaptive gravity compensation (AGC) offers a promising alternative, counterbalancing gravitational torques while continuously adapting to neuromuscular activity. However, these approaches have not been systematically compared in a human-in-the-loop setting. This study evaluates five control algorithms: two PMC strategies at different assistance levels, a purely integral AGC (AGC-PI), a kinematics- and acceleration-aware model-based (MB) AGC (AGC-AW), and a novel MB AGC approach based on Recursive Least Squares (AGC-RLS) for online payload estimation. Fourteen healthy participants performed target-reaching tasks using an active elbow exoskeleton under 0 kg and 2 kg loading conditions. Performance metrics included muscular activity, movement accuracy, task efficiency, and subjective workload. PMC exhibited a trade-off between physical effort and task performance: low assistance levels required greater physical effort under load, whereas high gains impaired task execution. AGC-PI reduced agonist activity but induced antagonist activation. In contrast, both model-based AGC approaches effectively compensated for external payloads, reducing physical and cognitive demands while improving movement accuracy and completion time.

Lower-limb exoskeletons have made considerable progress in reducing energy expenditure during walking. However, designing optimal assistance strategies remains challenging, particularly given inter-individual variability in anthropometry and biomechanics. This study explores energy-optimal lower-limb joint-assistance strategies using predictive simulations with musculoskeletal models. Subject-specific models of six able-bodied subjects, with BMI-based muscle strength scaling, were used in predictive simulations to generate gait at self-selected walking speeds. Ideal actuators were incorporated to simulate various combinations of joint assistance at peak levels of 25 Nm and 50 Nm to examine the effects of assistance on gait and metabolic savings. The effects of each assistance configuration were assessed through cost of transport (COT), joint kinematics, muscle activations, assistive torques, and joint-level power metrics to characterize the biomechanical and energetic impacts of different assistance strategies. At 50 Nm, combined H+K+A (hip-knee-ankle) assistance resulted in the greatest mean COT reduction of 48.50 +/- 4.55%, with individual reductions ranging from 42.22% to 54.65% across the subjects. Among single-joint conditions, assisting the hip was most effective, reducing COT by 31.77 +/- 5.21%; the knee and ankle produced smaller, comparable reductions (19.17% and 17.02%). H+A (hip-ankle) assistance (44.60 +/- 7.08%) emerged as the most effective two-joint assistive configuration. Increasing the torque bound increased positive assistive power primarily at the hip and ankle, while knee assistance showed little sensitivity and delivered positive power near pre-swing. These results support H+A assistance as an efficient two-actuator target, while identifying the knee's atypical pre-swing power strategy as a candidate for targeted experimental validation.

Pneumatic artificial muscles have provided new opportunities to develop upper-extremity soft exosuits for reha- bilitation, augmentation, and assisted daily living. However, the complex dynamics and limited bandwidth of these actuators has made providing responsive assistance based on user intention a longstanding challenge. In this work, we present an inverse-plant control strategy for pneumatically actuated soft exosuits that only relies on kinematic sensing for task-agnostic and dynamic assistance during daily living. We model the human-robot system using a Hammerstein dynamic model, consisting of a Preisach hysteresis model and a linear time-invariant filter, to capture the static and dynamic behavior of the system. We personalize our model to each user using 140 s of data and approximate an inverse to integrate into our control loop. When evaluated on a test rig that emulated a soft assistive exosuit for the wrist, our controller reduced the interaction torque by up to 73% and the activation of key flexor and extensor muscles by up to 47% relative to the condition with no assistance for speeds ranging from 8°/s to 120°/s. Overall, this work presents a control strategy that can provide task-agnostic, dynamic assistance with pneumatically actuated soft exosuits without the need for physiological or force sensors to interpret user intention.

Providing assistance across diverse movements is a central objective of exoskeletons, and anatomical knowledge can enable responsive support that generalizes across tasks. However, anatomical assistance has mainly been studied for lower-limb exoskeletons, where periodic, weight-bearing motions impose lower demands on torque precision. Extending such assistance to complex, nonperiodic upper-limb movements remains challenging. This paper proposes Anatomical Torque with Passivity-Based Control (ATP) for safe upper-limb exoskeleton assistance. First, a scalable musculoskeletal simulation framework trains a unified reinforcement-learning muscle controller that generalizes across upper-limb movements and generates anatomical reference torques without complex biomechanical computations. Second, an online torque-refinement scheme adapts the reference to diverse movements, suppresses tendon-induced spikes, and incorporates a learned anomaly score for safe and comfortable assistance. Third, an interaction torque controller delivers assistance through a cable-driven compliant exoskeleton without constraining motion to predefined trajectories, while an energy tank preserves passivity with theoretical guarantees on torque tracking and system passivity. Simulations and real-world experiments show accurate tracking of long-duration motion sequences and generalization to real-time human movements. The controller achieves accurate torque tracking while preserving passivity and resumes tracking after energy-tank replenishment. An EMG study with five participants further shows reduced target-muscle activity during static and dynamic tasks compared with gravity compensation and open-loop assistance, with reductions of up to 48% relative to movement without the exoskeleton in a dynamic multi-joint task.

Adaptive torque prediction in dynamic exoskeleton scenarios requires expensive motion capture systems, which are infeasible in complex outdoor environments. Trajectory prediction has emerged as one of the effective approaches to address such an issue. However, the core challenges of exoskeleton trajectory prediction are twofold: establishing the mapping from multi-modal features to trajectory information; constructing the mapping from trajectory to torque. For the former, most existing methods perform only single-step prediction and neglect inter-subject trajectory variability, thereby limiting the trajectory optimization space and prediction generalization. To address this, this paper proposes a fast flow matching method that enables accurate trajectory prediction and better generalization for real-time performance, where trajectory generation errors and encoded observations are used to guide the training direction. For the second challenge, due to the high dynamics of the human-robot system and the strong coupling between perception and control, simple control methods struggle to achieve efficient assistance based on the predicted trajectory. This paper utilizes model predictive control and designs a novel optimization objective to optimize torque, ensuring the exoskeleton achieves comfortable and robust assistance. By integrating the above two components, the unified policy, denoted as ExoTraj, is developed to enable adaptive assistance in complex outdoor scenarios without high data acquisition cost. Experimental results show that compared to traditional methods, ExoTraj reduces cross-subject prediction error by 14.0% during the online phase and maintains robustness against external noise. Relative to the zero torque condition, ExoTraj decreases metabolic rate by 11.5-24.4%, heart rate by 1.7-19.5%, and peak muscle activation levels by 10.9-41.3%, respectively.

Lower-limb exoskeletons require actuation systems that can provide accurate joint torque control while preserving low mass and encumbrance. Conventional architectures often rely on independently actuated joints and joint-level torque sensors, increasing system complexity and weight. This paper presents a novel differential actuation architecture for hip-knee flexion/extension, enabling cooperative torque sharing between two motors via a linear differential mapping between motor and joint. To compensate for transmission losses, a model-based friction estimation strategy is developed and experimentally implemented, allowing accurate joint torque estimation without the need for torque sensors. The proposed solution is validated on a physical prototype, demonstrating the feasibility of sensorless torque estimation in a differentially actuated hip-knee module of a lower-limb exoskeleton.

For robots to work safely in household environments, they need to be compliant and react to torque and force feedback during contact. However, the majority of existing data collection pipelines still lack the ability to capture force and torque data for learning active compliant policies. In this paper, we present Universal Manipulation Exoskeleton (UME), an upper-limb exoskeleton that provides real-time haptic torque feedback while recording whole-arm configurations and joint torque signals for teleoperation. With transparent torque feedback, human operators can even unsheathe kinematically constrained objects while blindfolded. UME is low-cost, lightweight, and portable. Equipped with an embedded IMU, it enables teleoperation for mobile manipulation. With our proposed universal retargeting algorithm, UME can teleoperate a range of robots, including the 7DoF OpenArm, 7DoF Franka, and 6DoF X-ARM. We demonstrate that this combination of capabilities enables learning bimanual, whole-body, and active compliant policies that operate effectively in highly constrained spaces. The learned robust autonomous policies achieve high success rates across a variety of tasks, including long-horizon mobile manipulation, force-mediated box flipping, visually occluded box pushing, and space-constrained tabletop manipulation. Videos, code, and additional information can be found at https://ume-exo.github.io.

Lower limb exoskeletons (LLEs) present the potential to make motor-impaired individuals walk again. Their application in real-world environments is still limited by the lack of effective adaptive gait planning. Indeed, current exoskeletons are meant to walk only on a flat and even terrain. Generating environment-aware, physiologically consistent gait trajectories in real-time is an open challenge. To overcome this, we propose a novel Kernelized Movement Primitives (KMP)-based framework for adaptive gait generation (AGG) across multiple indoor terrains. The proposed approach learns a probabilistic representation of human gait in both the joint and task spaces from a limited number of human demonstrations, representing natural gait characteristics and ensuring kinematic feasibility. In addition, the learned trajectories are adapted using environmental information extracted from an onboard RGB-D camera by treating the AGG as a linearly constrained optimization problem with via-points. The proposed method has been thoroughly validated first in simulations for gait generation in different scenarios, such as flat-ground walking, slopes, stairs, and obstacles crossing. Finally, the effectiveness and robustness of the method have been demonstrated with experiments on a commercial LLE in real-world scenarios. The results obtained demonstrate the feasibility of an environment-aware gait planning system for a new generation of intelligent lower limb exoskeletons for assisting people with disabilities in their every-day life.

Upper-limb exoskeletons (ULEs) have the potential to restore functional independence in individuals with severe motor impairments; however, the clinical relevance of wrist degrees of freedom (DoF), particularly abduction-adduction (Ab-Ad), remains insufficiently evaluated. This study investigates the functional and user-perceived impact of wrist Ab-Ad assistance during two activities of daily living (ADLs). Wrist Ab-Ad assistance in a tongue-controlled 6-DoF ULE, EXOTIC2, was evaluated in a within-subject study involving one individual with amyotrophic lateral sclerosis and five individuals with spinal cord injury. Participants performed drinking and scratch stick leveling tasks with EXOTIC2 under two conditions: with and without wrist Ab-Ad assistance. Outcome measure included task success, task completion time, kinematic measures, and a usability questionnaire capturing comfort, functional perception, and acceptance. Enabling wrist Ab-Ad improved task success rates across both ADLs, with consistent reductions in spillage (from 77.8% spillages to 22.2%) and failed placements (from 66.7% to 16.7%). Participants utilized task-specific subsets of the available wrist range of motion, indicating that effective control within functional ranges was more critical than maximal joint excursion. Questionnaire responses indicated no increase in discomfort with the additional DoF and reflected perceived improvements in task performance. In conclusion, wrist Ab-Ad assistance enhances functional task performance in assistive exoskeleton use without compromising user comfort. However, its effectiveness depends on task context, control usability, and individual user strategies. This study provides clinically relevant, user-centered evidence supporting the inclusion of wrist Ab-Ad in ULEs, emphasizing the importance of balancing functional capability with usability in assistive device design.

Wrist function is essential in performing activities of daily living (ADLs). However, there is limited experimental evidence on the functional impact of wrist Abduction-Adduction (Ab-Ad) joint assistance in upper limb exoskeletons (ULEs) for rehabilitation. This study evaluates the effect of implementing an active wrist Ab-Ad joint in a five degree of freedom (DoF) ULE, EXOTIC2 exoskeleton, to support individuals with severe motor impairments. Methods: A compact, lightweight wrist module with tendon-driven abduction and spring-driven adduction was integrated into the EXOTIC exoskeleton. Eight adults with no motor disabilities completed drinking and scratching tasks under randomized wrist-enabled and wrist-locked conditions along with a preliminary feasibility test in one individual with Amyotrophic lateral sclerosis (ALS). Kinematic and task performance metrics including wrist range of motion, task completion time, spillage and leveling metrics were assessed. Results: Implementing the wrist Ab-Ad DoF improved task success metrics. Spill incidence during the drinking task decreased from 56% to 3%, and leveling success for scratching task improved from 28% to 75%. Conclusion: Integrating wrist Ab-Ad assistance improved key functional task outcomes without increasing execution time. Significance: The study provides the experimental evidence that active wrist Ab-Ad control enhances task-level performance in exoskeleton-assisted ADLs.

Robot-assisted therapy can deliver high-dose, task-specific training after neurologic injury, but most systems act primarily at the limb level-engaging the impaired neural circuits only indirectly-which remains a key barrier to truly contingent, neuroplasticity-targeted rehabilitation. We address this gap by implementing online, dual-state motor imagery control of an upper-limb exoskeleton, enabling goal-directed reaches to be both initiated and terminated directly from non-invasive EEG. Eight participants used EEG to initiate assistance and then volitionally halt the robot mid-trajectory. Across two online sessions, group-mean hit rates were 61.5% for onset and 64.5% for offset, demonstrating reliable start-stop command delivery despite instrumental noise and passive arm motion. Methodologically, we reveal a systematic, class-driven bias induced by common task-based recentering using an asymmetric margin diagnostic, and we introduce a class-agnostic fixation-based recentering method that tracks drift without sampling command classes while preserving class geometry. This substantially improves threshold-free separability (AUC gains: onset +56%, p = 0.0117; offset +34%, p = 0.0251) and reduces bias within and across days. Together, these results help bridge offline decoding and practical, intention-driven start-stop control of a rehabilitation exoskeleton, enabling precisely timed, contingent assistance aligned with neuroplasticity goals while supporting future clinical translation.

Robotic systems can enhance the amount and repeatability of physically guided motor training. Yet their real-world adoption is limited, partly due to non-intuitive trainer/therapist-trainee/patient interactions. To address this gap, we present a haptic teleoperation system for trainers to remotely guide and monitor the movements of a trainee wearing an arm exoskeleton. The trainer can physically interact with the exoskeleton through a commercial handheld haptic device via virtual contact points at the exoskeleton's elbow and wrist, allowing intuitive guidance. Thirty-two participants tested the system in a trainer-trainee paradigm, comparing our haptic demonstration system with conventional visual demonstration in guiding trainees in executing arm poses. Quantitative analyses showed that haptic demonstration significantly reduced movement completion time and improved smoothness, while speech analysis using large language models for automated transcription and categorization of verbal commands revealed fewer verbal instructions. The haptic demonstration did not result in higher reported mental and physical effort by trainers compared to the visual demonstration, while trainers reported greater competence and trainees lower physical demand. These findings support the feasibility of our proposed interface for effective remote human-robot physical interaction. Future work should assess its usability and efficacy for clinical populations in restoring clinicians' sense of agency during robot-assisted therapy.

Portable pneumatic systems for 2 degree-of-freedom (DOF) soft shoulder exosuits remain underexplored, and face fundamental trade-offs between torque output and dynamic response that are further compounded by the need for multiple actuators to support complex shoulder movement. This work addresses these constraints through a volume-optimized spindle-shaped angled actuator (SSAA) geometry: by reducing actuator volume by 35.7% (357mL vs. 555mL), the SSAA maintains 94.2% of output torque while achieving 35.2% faster dynamic response compared to uniform cylindrical designs. Building on the SSAA, we develop a curved abduction actuator (CAA) based on the SSAA geometry and a horizontal adduction actuator (HAA) based on the pouch motor principle, integrating both into a dual-DOF textile-based shoulder exosuit (390 g). The exosuit delivers multi-modal assistance spanning shoulder abduction, flexion, and horizontal adduction, depending on the actuation. User studies with 10 healthy participants reveal that the exosuit substantially reduces electromyographic (EMG) activity across both shoulder abduction and flexion tasks. For abduction with HAA only, the exosuit achieved up to 59% muscle activity reduction across seven muscles. For flexion, both the single-actuator configuration (HAA only) and the dual-actuator configuration (HAA,+,CAA) reduced EMG activity by up to 63.7% compared to no assistance. However, the incremental benefit of adding the CAA to existing HAA support was limited in healthy users during flexion, with statistically significant additional reductions observed only in pectoralis major. These experimental findings characterize actuator contributions in healthy users and provide design guidance for multi-DOF exosuit systems.

Squatting is one of the most demanding lower-limb movements, requiring substantial muscular effort and coordination. Reducing the physical demands of this task through intelligent and personalized assistance has significant implications, particularly in industries involving repetitive low-level assembly activities. In this study, we evaluated the effectiveness of a neural network controller for a modular Hip-Knee exoskeleton designed to assist squatting tasks. The neural network controller was trained via reinforcement learning (RL) in a physics-based, human-exoskeleton interaction simulation environment. The controller generated real-time hip and knee assistance torques based on recent joint-angle and velocity histories. Five healthy adults performed three-minute metronome-guided squats under three conditions: (1) no exoskeleton (No-Exo), (2) exoskeleton with Zero-Torque, and (3) exoskeleton with active assistance (Assistance). Physiological effort was assessed using indirect calorimetry and heart rate monitoring, alongside concurrent kinematic data collection. Results show that the RL-based controller adapts to individuals by producing torque profiles tailored to each subject's kinematics and timing. Compared with the Zero-Torque and No-Exo condition, active assistance reduced the net metabolic rate by approximately 10%, with minor reductions observed in heart rate. However, assisted trials also exhibited reduced squat depth, reflected by smaller hip and knee flexion. These preliminary findings suggest that the proposed controller can effectively lower physiological effort during repetitive squatting, motivating further improvements in both hardware design and control strategies.