Domain Generalization

Machine learning models often degrade when they are deployed on a target distribution that differs from the source distributions they were trained on. Recent work in causality-based domain generalization has shown how shared causal structure between domains can induce invariant predictors, e.g., models on a subset of features which have stable risk across structured domain shifts. However, the extent to which such population-level causal invariances can lead to gains in finite-sample settings remains underexplored. In particular, in practice we often have access to a few labeled target samples, a setting called supervised domain adaptation (sDA). In this paper, we explore when (full or partial) causal knowledge can provably improve supervised domain adaptation. As a first step, we study linear regression, where full or partial causal knowledge specifies a collection of invariant or possibly invariant feature subsets, each yielding a source-trained candidate predictor. We derive matching upper and lower bounds showing that finite-sample gains are governed by the target-risk margins separating the candidates, together with the finite-source estimation error. When these margins are sufficiently large relative to $n_Q$, an adaptive aggregation procedure can match the best candidate predictor while avoiding negative transfer relative to target-only learning. On the other hand, when the margins are too small, no algorithm can reliably exploit the candidate collection to obtain faster finite-sample rates. We further connect these margins to structural shift magnitude in linear SCMs and validate the theory on real-world causal benchmarks.

Vision-Language-Action (VLA) models that couple pretrained Vision-Language Models (VLMs) with continuous action experts have achieved strong manipulation performance, yet generalization to out-of-distribution (OOD) language instructions remains poor. A known challenge is the structural imbalance in VLA data, where language is far less diverse than visual and action content, making policies prone to visual shortcuts. While discrete-action methods mitigate this through vision-language co-training, continuous action experts lack such protection: they start from random initialization and learn entirely from imbalanced data, producing noisy gradients that corrupt the VLM and fail to exploit its language capability. We address this from a Bayesian perspective, factorizing the policy into a language-agnostic Vision-Action (VA) prior and a language-conditioned VLA likelihood, and propose APT, a two-stage training method emphasizing Action expert PreTraining. In Stage 1, the action expert is pretrained as a VA prior on vision-action pairs from a frozen VLM, bypassing the language imbalance. In Stage 2, language tokens are injected through a gated fusion mechanism that integrates VLM features while preserving the learned visuomotor prior. APT applies to mainstream VLA architectures, including the $π$ and GR00T-style architectures. Comprehensive experiments validate that APT achieves consistent gains on unseen instructions and compositional tasks. Project Page: https://xukechun.github.io/papers/APT/

Most existing deep learning-based PET image denoising methods assume a fixed and known dose reduction factor (DRF) for low-dose PET images. However, these methods encounter significant performance degradation when the DRF varies beyond the assumed one in practical applications. To address the challenge posed by varied DRFs, several preliminary studies focus on the task of universal PET image denoising, aiming to train a universal model over low-dose data across DRFs. Nonetheless, these vanilla universal models often struggle with misaligned styles present in different DRF data, leading to the \textit{style elimination issue} with a significant over-smoothing effect. To deal with this issue, we innovatively introduce domain generalization to PET image denoising and propose a universal PET image denoising network (UniPET) to achieve high-quality PET image denoising across diverse DRFs. UniPET comprises two primary innovations: a style alignment network (SAN) and a region-aware learning strategy (RALS). Specifically, SAN utilizes style alignment techniques derived from domain generalization to align and recover styles across different DRFs, ensuring the model's generalizability across various DRFs while effectively preserving styles. Furthermore, to enhance style recovery, RALS distinguishes between flat and stylized regions, exclusively conducting adversarial learning on the latter, thereby more effectively guiding the model's focus towards learning stylized regions. It is demonstrated that our proposed UniPET can adaptively recover different DRF styles and achieve high-quality PET image denoising across DRFs. Comprehensive experiments show that UniPET exhibits comparable performance to individual DRF-specific models at specific DRFs and realizes state-of-the-art performance in universal PET image denoising quantitatively, perceptually, and clinically.

In real-world deployment under strict real-time constraints, weather and imaging variations induce significant distribution shifts, severely degrading detectors. Single-Domain Generalized Object Detection aims to mitigate this issue, yet existing methods rarely investigate-at the level of problem formulation-the generalization capability of real-time detectors under such constrained inference budgets. To this end, we introduce Real-Time Single-Domain Generalized Object Detection (RT-SDGOD), which focuses on how real-time detectors can achieve cross-domain generalization under zero extra inference overhead by relying solely on training-time representation learning. We observe that, under domain shift, DETR-based real-time detectors mainly degrade through increased missed detections, rooted in limited and unstable object-level discriminative evidence. Based on this, we propose RT-SDGDet, a multi-evidence collaborative modeling framework for RT-SDGOD. The core idea is to enable multiple queries of the same object to collaboratively cover more sufficient discriminative evidence while maintaining the stability of such evidence modeling across views. Specifically, we use one-to-many (O2M) supervision to construct stable object-specific query groups, and further design Discriminative Evidence Diversity Learning (DEDL) and Dual-view Evidence Consistency Learning (DvECL) to expand object-level evidence coverage and improve evidence stability under appearance perturbations, respectively. Since all components are introduced only during training, our method incurs no extra inference overhead. Extensive experiments show that the proposed method achieves better generalization performance than existing approaches across multiple unseen target domains.

Open-domain open-vocabulary detection (ODOVD) requires detectors to generalize to both novel categories and unseen domains, making it more challenging than open-vocabulary detection. Existing methods typically train open-vocabulary detectors together with domain generalization modules from scratch, leading to high training cost. we propose ExDet, a lightweight category-domain collaborative generalization framework for ODOVD that enhances the cross-category and cross-domain generalization of existing detectors. ExDet consists of Text-Guided Extrapolation (TGE), a lightweight Detector-Compatible Rectification (DCR) module, and ExRPN. Specifically, TGE exploits the DeltaSpace property of vision-language models (VLMs) to infer category- and domain-aware proxy visual prototypes from text. DCR is learned from the TGE-generated prototypes in a detector training-free and real-data-free manner, and is inserted after the classification head at inference to rectify representations toward a detector-compatible source-domain visual distribution, thereby enhancing classification for targets from novel categories and unseen domains. ExRPN recalibrates proposal scores by combining semantic similarity with RPN confidence, improving recall for novel and domain-shifted objects while providing better support for subsequent classification and DCR. ExDet achieves SOTA performance on OD-LVIS, OV-LVIS, Objects365, and MSOSB.

The increasing use of large language models has raised concerns about the spread of AI-generated fake news, particularly under varying prompting strategies. Most existing detection models are trained and evaluated under a single generation setting, leaving their ability to generalize across unseen prompts unclear. In this study, we investigate cross-prompt generalization in fake news detection using three datasets of AI-generated articles produced under distinct prompts, combined with real news articles. We extract interpretable linguistic features capturing lexical diversity, readability, and emotion-based characteristics and evaluate a random forest classifier under a cross-prompt framework, where models trained on one prompt are tested on another. Across all six train-test combinations, performance remains consistently high, with AUC values ranging from 0.988 to 1.000. Analysis of feature distributions shows that AI-generated text exhibits increased lexical diversity, reduced readability, and substantially lower emotional intensity compared to the overall dataset, with variations across prompts. Despite these distributional shifts, the classifier maintains strong performance, indicating that these features capture stable properties of AI-generated text that generalize across prompting strategies. These findings suggest that feature-based approaches can provide robust detection of AI-generated fake news under prompt variability.

Interpretable linguistic features offer a promising approach for explaining why a given text appears machine-generated, particularly for non-expert users. However, existing findings on which features reliably indicate LLM-generated text remain fragmented across feature sets, models, and text domains. To address this gap, we conduct a large-scale empirical study assessing the robustness of linguistic signals for characterizing AI-generated text. Our analysis covers 284 interpretable linguistic features across outputs from 27 LLMs and ten text domains under cross-model and cross-domain generalization settings. We show that classifiers based solely on linguistic features can reliably distinguish AI-generated from human-written text. However, many previously proposed indicators prove strongly context-dependent, with the exception of measures of lexical richness, which remain robust signals across model families and text domains. These results demonstrate which linguistic signals generalize across contexts and provide a foundation for more reliable, interpretable analyses of AI-generated language.

Air pollution represents one of the most critical environmental and public health challenges globally, with traditional sensor-based monitoring systems facing significant scalability and economic constraints. Image-based air quality estimation has emerged as a promising alternative, leveraging the visual characteristics of atmospheric pollutants in traffic scenes. However, existing methods suffer from limited cross-city generalization and inadequate exploitation of multi-view perspectives. We present AQIFormer, a novel transformer-based ensemble architecture that addresses these fundamental limitations through innovative dual-view integration, weather-aware attention mechanisms, and comprehensive multi-task learning. Our approach uniquely combines front and rear traffic imagery with meteorological parameters to achieve robust air quality classification across diverse urban environments. Extensive evaluation on a comprehensive dataset of 26,678 synchronized front-rear image pairs demonstrates good performance with 89.96% accuracy, representing a 14.96% improvement over state-of-the-art methods. Most importantly, our model maintains exceptional cross-city generalization capabilities, achieving 81.67% accuracy on an independent dataset collected in Nagpur, India with only 8.29% performance degradation using few-shot adaptation with minimal training samples.

Multi-modal Domain Generalization (MMDG) seeks to leverage complementary modalities to enhance model robustness on unseen domains. Despite extensive progress in Multi-modal Learning (MML) and Domain Generalization (DG) as individual fields, their systematic integration remains under-explored. Current MMDG research is largely confined to action recognition and lacks standardized evaluation protocols. To address this, we introduce MMDG-Bench, a comprehensive benchmark featuring two foundational frameworks: DG then MML (D2M) and MML then DG (M2D). We provide unified experimental protocols across diverse tasks, including video-audio-flow action recognition and RGB-Depth-IR face anti-spoofing. By instantiating ten MMDG baselines through pairing a unified MML configuration with five DG techniques under both D2M and M2D orderings, we demonstrate that these structured combinations frequently outperform existing state-of-the-art methods, underscoring the necessity of a unified benchmarking effort. Our analysis yields three key insights: (1) Integrating DG techniques provides consistent generalization gains across various backbones, whereas non-DG methods are highly sensitive to backbone shifts; (2) The optimal framework choice depends on inter-modal stability: D2M excels when modal relations are stable across domains, while M2D is more robust to cross-domain relational variance; (3) Stronger backbones yield amplified performance dividends when integrated into our structured frameworks. MMDG-Bench provides a principled foundation and actionable design guidelines for future research in multi-modal robustness. Code is released at https://github.com/qszhan/MMDG-Bench.

Large-scale recommendation systems operate across diverse domains, yet they face the challenges of data sparsity and noisy implicit feedback. Traditional approaches mitigate this via model-specific knowledge distillation from source domains to a target domain. Inspired by the transformative success of synthetic data generation in large language models (LLMs), we introduce Synthetic Cross-domain Augmentation and Learning for Recommendation (SCALR), a framework that generates synthetic user-item interaction events for a target recommendation domain by leveraging observed events from a source domain. SCALR decomposes cross-domain learning into two modular stages. First, it translates observed user events in source domains by framing event generation as estimating the likelihood that a user would interact with a target-domain item, conditioned on their observed interactions in a source domain. Second, downstream models train on these synthetic events as cross-domain learning objectives, where the synthetic events augment the target domain's training data in a model-agnostic manner. Our approach yields statistically significant improvements in online A/B tests on an industrial recommendation platform. To the best of our knowledge, this is among the first works to explicitly frame cross-domain event transfer as synthetic data generation for recommendation systems.

Robot manipulation critically depends on perception that preserves the action-relevant aspects of a scene. Yet most robot learning pipelines are built upon visual encoders pre-trained for static recognition or vision-language alignment, leaving motion understanding to downstream policies. We introduce DynaFLIP, a dynamics-aware multimodal pre-training framework that pushes motion understanding upstream into perception. We construct image-language-3D flow triplets from heterogeneous human and robot videos, and use these triplets as training-time supervision to shape an image-only encoder. Our key idea is to encourage the three modalities to span a small simplex volume in the shared hyperspherical space -- a smaller simplex volume indicating stronger alignment. To avoid the geometric ambiguity and trivial collapse of naive volume minimization, we combine simplex-volume minimization with a cosine regularizer and a contrastive objective. Our analyses show that DynaFLIP focuses on control-relevant regions critical for manipulation. The resulting dynamics-aware representations serve as reusable visual backbones and consistently outperform baselines across diverse downstream policies, including VLAs. We validate this across diverse simulation and real-world setups, with gains reaching +22.5% under out-of-distribution scenarios. Our results suggest that robot generalization improves when visual representations are trained to encode not just what is present, but how the world changes under action.

Autonomous driving systems are commonly trained and evaluated within limited geographic regions, which hinders their scalability when deployed in new cities. However, significant domain shifts in appearance, road topology, and traffic patterns often cause severe performance degradation under cross-city deployment. Existing approaches based on domain adaptation, data augmentation, or synthetic data generation typically rely on labeled target data, city-specific annotations, or task-specific designs, limiting their scalability and effectiveness for holistic evaluation. In this paper, we introduce CityTransfer-Bench, a geographically disjoint benchmark for evaluating cross-city generalization across perception, segmentation, and planning, and propose CityGen, a diffusion-based generative framework that performs zero-label city adaptation via HD-map-conditioned synthesis guided by city-level visual prompts. Extensive experiments demonstrate that CityGen consistently improves cross-city robustness across multiple tasks, establishing a scalable and label-efficient foundation for generalizable autonomous driving.

AI-driven respiratory sound classification (RSC) is promising for automated pulmonary disease detection, yet multi-site deployment is hindered by inter-stethoscope variability. We introduce a federated domain generalization (FedDG) formulation for RSC in which clients hold recordings from different stethoscopes and the model is evaluated on an unseen device. Our empirical analysis shows that stethoscope-induced style and disease-relevant content are partially entangled, making deterministic style removal unreliable. In response, we propose BTS-CAFE, a framework combining (i) causality-inspired device-style interventions with constraints designed to limit content distortion, (ii) counterfactual metadata augmentation to relieve device and demographic shortcuts, and (iii) gradient alignment to promote device-invariant decision boundaries across clients. Built on BTS with CLAP, a multimodal language-audio pretraining model, BTS-CAFE improves the out-of-distribution ICBHI Score by 3.69 points on average over five held-out devices relative to its backbone, and outperforms conventional data augmentation and federated learning baselines in simulated device leave-out evaluations on the ICBHI and SPRSound datasets.

It is often desirable to generalize medical imaging AI models trained with dense annotations to data acquired from different ultrasound scanners or clinical sites; however, retraining these models with new annotations is often difficult and costly. We examine this challenge in pediatric wrist fracture assessment using point-of-care ultrasound (POCUS), where fractures are common and can be effectively triaged via ultrasound. AI has shown radiologist-level performance for fracture detection, often aided by high-quality bony structure segmentation. However, due to significant domain shifts, models perform poorly on data from other centers or probes, and obtaining segmentation labels across devices is impractical due to manual annotation effort and data privacy concerns. To address this, we propose a target-informed self-supervised pretraining and model-ensemble strategy. Specifically, our approach combines masked image modeling (MIM) and contrastive learning to learn target-domain structural representations without labels, and introduces a confidence-aware infusion head to adaptively integrate predictions. The source dataset, collected with a Philips Lumify probe, contained dense labels, while the target dataset, acquired with a TeleMED portable probe, was unlabeled. The datasets were kept strictly separate throughout the entire process. Our method used labeled source data for supervised training and leveraged target-domain pretraining to improve generalization. On 318 images from 62 pediatric POCUS videos, this approach significantly improved cross-device performance, achieving over 6% Dice improvement on the target domain versus the baseline. These results demonstrate a label-efficient and privacy-preserving approach for cross-device-robust ultrasound AI, offering a framework that can be extended to multi-center studies or federated learning setups.

Urban representation learning encodes complex urban environments into general-purpose embeddings for diverse downstream tasks and emerging urban foundation models. However, current evaluations are limited, typically focusing on one or two cities and tasks and relying on random splits that introduce spatial leakage, leading to inflated performance and weak support for cross-location generalization and fair comparison. To address this, we propose CityRep, a unified benchmark that evaluates urban representations across data modalities, cities, and tasks using spatially structured splits. CityRep consists of three key components: (1) a spatial unit-agnostic evaluation framework that supports heterogeneous urban representations through a standardized alignment module; (2) a unified evaluation protocol using block-based spatial splits to mitigate spatial leakage and enable rigorous model comparison; and (3) an extensible multi-city, multi-task benchmark suite spanning 8 cities and 8 tasks across regression, classification, and distribution prediction. We evaluate 11 representative urban representation models. Results show that performance is highly sensitive to the split protocol, with random splits inflating scores and altering model rankings. We also observe substantial variability across cities and tasks, underscoring the need for generalization-aware evaluation. CityRep is released as a reproducible benchmark with datasets, evaluation pipelines, and diagnostic tools to facilitate fair comparison and support future research in urban representation learning towards urban foundation models.

Scribble-guided image editing allows users to combine simple scribble annotations with text prompts to specify both where and how an image should be edited, enabling flexible interaction with precise spatial control. However, existing models still exhibit unstable performance under this paradigm, especially in multi-task scenarios. To improve performance, we conduct empirical studies using an open-source editing model and reveal an asymmetry in generalization: instruction-level generalization, including across editing tasks and from single-task to multi-task settings, is more challenging than image-domain generalization, such as from synthetic to real-world images or from mosaicked to regular images. This suggests that the primary bottleneck lies in insufficient learning for diverse editing instructions rather than in the image domain gap. Motivated by this insight, we propose three strategies: (a) a Coverage-then-Realism Curriculum, a two-stage pipeline that first builds large-scale synthetic, instruction-rich data for broad task supervision, then curates a small set of real-world data to refine generation realism; (b) Multi-Task Mosaicking, which constructs multi-task training samples by concatenating single-task examples at nearly zero cost while enabling the learned capability to generalize to non-mosaicked images; and (c) an Edit-Focused Loss, which leverages the changed regions between input and output images in synthetic data to focus training on edited regions, improving both learning efficiency and editing accuracy. With these strategies, we substantially improve both single-task and multi-task scribble-guided editing on the VIBE benchmark, achieving state-of-the-art results. We will publicly release our dataset and model.

With unified model-generated images now widespread online, attributing their model of origin offers a path toward transparency and deeper insight into the characteristic behaviors of individual models. Prior work has explored provenance in LLM-generated text, diffusion model images, and datasets, but the separability of unified model-generated images remains an underexplored area. We address this gap by examining separability across corruption, domains, and prompt languages using images generated by seven unified models. We show that model attribution is highly feasible as our model achieves near-perfect accuracy with around 20K images per model. Corruptions and structural perturbations have only a modest effect on attribution performance, and cross-domain generalization reveals that semantic content contributes to separability but is not the dominant signal. Finally, we observe that for most models, prompt language attribution is around chance levels, suggesting minimal language-specific visual signatures. These findings highlight consistent model-specific visual characteristics in unified models outputs and open new directions for tracing and auditing generative image pipelines.

Prediction models trained under the source distribution do not generalize well to a different target distribution. A valid inference about an unseen data distribution must be anchored by the invariance of certain causal mechanisms that generate the source and target data, however, these structural invariances are non-identifiable from the source data alone. Under mild causal assumptions about the data, we show that the optimal prediction in the target is in fact partially identifiable by the source distribution. The result rests on a simple observation: In any domain, the optimal prediction can be factorized into what we call a pair of abduction and deduction maps, where the abduction map makes inference about some unobserved variables (possibly confounders) from the observed variables and the deduction map predicts the label using both the observed and inferred quantities. Access to large source data pins down the optimal prediction, thus constrains the valid abduction-deduction ensembles that produce it -- a non-identifiability that we call the abduction-deduction entanglement. To leverage this, we parameterize the constrained family using what we call a representation transplant, that is a specific linear transformation in the representation space that manipulates the abduction content of the representation while retaining the deduction component. Invariance of the causal mechanism generating the label implies existence of an invariant deduction map between source and target. Thus, we can search the space of plausible target distributions via a parametric transplant. We use this scheme in a learner-adversary game that, under an idealistic optimization, provably terminates with the learner having the minimax-optimal target prediction. Evaluations verify the theory, showing that the method is competitive in DG benchmarks.

The rapid evolution of generative models has enabled the creation of hyper-realistic facial deepfakes, exposing a critical vulnerability in modern digital forensics: the inability of detectors to generalize to unseen manipulation techniques. Traditional networks suffer from representation collapse, overfitting to localized artifact fingerprints of specific training generators. This work investigates whether modern Vision Foundation Models can serve as generalizable, out-of-the-box feature extractors capable of tracking forensic anomalies across entirely unseen generative manifolds. We conduct a systematic cross-domain evaluation comparing three foundational learning paradigms: fully supervised macro-semantic features (RoPE-ViT), pure self-supervised geometric features (DINOv3), and multi-teacher agglomerative representations (NVIDIA C-RADIOv4-H). By deploying frozen backbones subjected to downstream linear probing, we map the performance limitations of these architectures on the challenging DF40 benchmark. Our empirical findings expose the intrinsic trade-offs between pre-training paradigms and parameter scale, proving that while foundation models retain high discriminative capabilities for entire face synthesis, localized face editing techniques expose fundamental boundaries in linear probe evaluation structures. Source code and model weights are available in http://github.com/mribrahim/deepfake

Data streams in real-world industrial scenarios often contain transitional operating conditions that are uncovered during offline training, leading to significant distribution shifts. To bridge the gap between static offline models and dynamic online data, a novel asymmetric adaptation-based fault diagnosis method is proposed in this paper. Specifically, in the offline stage, we employ domain generalization techniques to extract domain-invariant features from multiple stable conditions and construct robust normalized fault prototypes as reference anchors. Subsequently, during online inference, we design an online test-time adaptation method based on a periodic prototype re-projection mechanism to dynamically update prototype positions. Furthermore, we utilize the geometric distribution derived from anchors to guide the updates of classifiers and adopt an asymmetric learning rate strategy for the feature extractor and classifier. The proposed approach ensures rapid adaptation to new transitional conditions while preserving the discriminative power inherited from the offline domain generalization initialization. Experimental results demonstrate that this mechanism effectively leverages offline generalized knowledge to guide online inference, significantly improving robustness in non-stationary environments.

Currently, Vision-Language-Action (VLA) models have become the most adopted paradigm for robotic manipulation for its great potential for task generalization. While most generative flow-matching action decoders for VLA control are often deployed with fixed sampling horizons, limiting state-dependent compute and temporal reuse across control cycles. We present $π_0$-EqM, which replaces the flow-matching expert in $π_0$ with an Equilibrium Matching (EqM) decoder while leaving the upstream VLA stack unchanged. Under a matched 300-step budget, $π_0$-EqM improves RoboTwin average success from 40.4% to 50.2% across 19 tasks and remains competitive on LIBERO, with its clearest gain on LIBERO-10 (87.0%). Two threshold scans reveal a task-dependent non-monotonic relation between residual and success, which we term the stationarity--executability gap. The results suggest that inference depth in iterative VLA control is part of policy design and introduce an energy-based VLA perspective that may inform future work on composable action generation across tasks and embodiments.

Domain generalization aims to enhance model robustness against unseen domains with embedding distribution shifts. While large-scale vision-language models like CLIP exhibit strong generalization, their direct image-text embedding alignment suffers from inherent information asymmetry: images encode both class semantics and domain-specific styles, whereas text prompts primarily convey basic class cues. This asymmetry hinders generalization to novel domains in realistic scenarios. To address this, we propose Style-Homogenized Embedding alignment for Domain-generalization (SHED), a novel CLIP-based method that aligns style-homogenized embeddings instead of raw representations from encoders in CLIP. During training, SHED removes domain-specific style centroids from both image embeddings computed per source domains and text embeddings which are averaged across diverse prompt templates and stripped of a global centroid. For inference, considering the lack of target domain information, SHED projects diverse textual domain centroids into the visual space and aggregates predictions via membership weighting. Extensive experiments on five benchmarks show SHED achieves state-of-the-art performance, outperforming prior methods significantly (e.g., +4.0% on DomainNet vs. standard fine-tuning).

Robust whole-slide image (WSI) analysis under strict data-governance remains challenging due to substantial cross-institutional stain heterogeneity. Domain generalization (DG) mitigates these shifts but typically requires centralized data, conflicting with privacy regulations. Federated learning (FedL) provides a decentralized alternative; however, existing FedL and federated DG (FedDG) approaches rely almost exclusively on low-order statistics, assuming Gaussian-like stain distributions. In contrast, real-world staining processes often produce asymmetric, heavy-tailed color distributions due to biochemical diffusion and scanner nonlinearity. Consequently, current methods fail to model the higher-order, non-Gaussian characteristics dominating real-world stain variability. To address this, we propose FedStain, a stain-aware FedDG framework explicitly incorporating higher-order stain moments--skewness and kurtosis--as compact statistical descriptors exchanged during federated optimization. These descriptors require no pixel-level data transmission, preserving strict privacy and communication efficiency, while enabling the global model to capture stain variability missed by low-order statistics. FedStain also employs a contrastive, cross-site parameter aggregation strategy to promote stain-invariant representations without relaxing data constraints. Extensive experiments on Camelyon17 and our new MvMidog-Fed benchmark show FedStain yields consistent improvements, outperforming state-of-the-art FedL, DG, and FedDG baselines by up to +3.9% absolute accuracy. To our knowledge, FedStain is the first FedDG approach to explicitly model higher-order stain statistics, enabling robust cross-institutional deployment in computational pathology.

Dataset Distillation (DD) synthesizes a compact synthetic dataset that preserves the training utility of a full dataset. However, its standard formulation assumes that test data follow the same distribution as training data, an assumption that rarely holds in practice. A straightforward extension-applying post-hoc Domain Generalization (DG) techniques to distilled data-is ill-suited because existing DG methods rely on the natural diversity of real datasets, which compact synthetic sets inherently lack, while also incurring substantial augmentation overhead that conflicts with the efficiency objective of dataset distillation. To address this limitation, we introduce Domain Generalizable Dataset Distillation (DGDD), a new problem setting that explicitly targets out-of-distribution (OOD) generalization of distilled datasets. We study this problem through a widely adopted DD baseline of Distribution Matching (DM). We attribute the OOD vulnerability of DM to the entanglement of class-discriminative and domain-specific information within the compressed synthetic set, and propose Spectral Gradient Surgery (SGS) to disentangle the two. The key insight of SGS is that cross-domain agreement among domain-wise gradients in the spectral domain reveals which gradient components are shared across source domains-and are therefore class-discriminative-and which are domain-specific. Based on this observation, SGS augments the standard DM update with two complementary gradients: one that reinforces cross-domain shared components and another that explicitly promotes diversity within the distilled dataset. Extensive experiments on diverse-scale benchmarks demonstrate that SGS substantially improves OOD generalization while remaining plug-and-play compatible with existing DM methods.

Using prompted language models as classifiers enables classification in domains with limited training data, but misses some of the robustness and performance benefits that fine-tuning can bring. We study whether training on multiple classification tasks, each with its own prompt, improves performance on new domains with new classification prompts. We show that such training partially generalizes to adjacent domains, improving classification performance on tasks that are unseen during training. However, we identify specific edge cases where the fine-tuned models fail to follow prompts, such as when the classification prompt changes completely while the data domain remains the same as during training. We show that classification training can be mixed with general instruction following training, and that (when done well) such training keeps the benefits of classification training and mitigates its generalization failures. Surprisingly, we see that this no-thinking supervised classification training can generalize to with-thinking classification and summarization, suggesting that no-thinking classification training might be instrumentally useful in building other kinds of classifiers and monitoring systems.

Pedestrian motion, due to its causal nature, is strongly influenced by domain gaps arising from discrepancies between training and testing data distributions. Focusing on 3D human pose estimation, this work presents a controllable human pose generation framework that synthesizes diverse video data by systematically varying poses, backgrounds, and camera viewpoints. This generative augmentation enriches training datasets, enhances model generalization, and alleviates the limitations of existing methods in handling domain discrepancies. By leveraging both indoor/real-world and outdoor/virtual datasets, we perform cross-domain data fusion and controllable video generation to construct enriched training data, tailored to realistic deployment settings. Extensive experiments show that the augmented datasets significantly improve model performance on unseen scenarios and datasets, validating the effectiveness of the proposed approach.

Multimodal learning seeks to integrate information across diverse sensory sources, yet current approaches struggle to balance cross-modal generalizability with modality-specific structure. Continuous (implicit) methods preserve fine-grained priors but render generalization challenging, while discrete (explicit) approaches enforce shared prototypes at the expense of modality specificity. We introduce CoDAAR (Cross-modal Discrete Alignment And Reconstruction), a novel framework that resolves this long-standing trade-off by establishing semantic consensus across modality-specific codebooks through index-level alignment. This design uniquely allows CoDAAR to preserve modality-unique structures while achieving generalizable cross-modal representations within a unified discrete space. CoDAAR combines two complementary mechanisms: Discrete Temporal Alignment (DTA), which enables fine-grained temporal quantization, and Cascading Semantic Alignment (CSA), which promotes progressive cross-modal semantic agreement. Together, they establish a competition-free unified representation space. Trained with self-supervised reconstruction objectives on paired multimodal sequences, CoDAAR demonstrates robust cross-modal and cross-domain generalization. Across Cross-Modal Generalization benchmarks, including event classification, localization, video segmentation, and cross-dataset transfer, CoDAAR achieves state-of-the-art performance, establishing a new paradigm for discrete and generalizable multimodal representation learning.

Deep learning-based website fingerprinting has emerged as an effective technique for inferring the websites users visit. Although existing methods achieve strong performance on closed-world datasets, they often fail to generalize to real-world environments, especially under geographic and temporal shifts. This limitation fundamentally stems from the coupled effects of two key challenges: application-layer resource composition variability and observable feature instability induced by cross-layer encapsulation. Intertwined, these factors induce systematic shifts between underlying application semantics and observable traffic features. To address the above challenges, we propose SATA , a semantics-aware traffic augmentation framework. Specifically, SATA first performs application-layer semantic augmentation based on protocol rules, expanding the resource composition patterns within each flow and frame sequence patterns under protocol constraints. Based on these augmented frame sequences, we further introduce a cross-layer feature alignment mechanism via knowledge distillation. It aligns frame sequence with packet-length sequence features, enabling cross-layer feature alignment between enhanced semantics and observable sequences. Extensive experiments show that SATA successfully generates traffic patterns that are absent from the training set but genuinely exist in the test set, and significantly improves the performance of mainstream models across diverse and complex scenarios. In particular, in open-world settings, SATA improves ACC by 90.81% and AUROC by 48.37%. The source code of the prototype system is available at https://anonymous.4open.science/r/SATA-B6C2/.

Pixel-level slum mapping has long been constrained by limited cross-city generalisation, the absence of continuous density estimation, and weak global comparability. AlphaEarth Foundations (AEF), a globally consistent 64-dimensional annual surface embedding at 10 m, offers a new analysis-ready basis for lightweight slum monitoring, but its applicability to slum detection - an indirectly coupled task shaped by both built form and socio-economic processes - remains untested. We evaluate AEF on slum classification and sub-pixel density estimation across 12 cities and 69 city-year pairs (2017-2024), using GRAM pseudo-masks as supervisory labels. The evaluation spans four training strategies, two protocols (random split and 3x3 spatial block cross-validation), six auxiliary feature configurations, and five baseline models, complemented by representation-level analyses (PCA, SHAP) and full-AOI mapping. Five findings emerge. (1) Same-city cross-year training is optimal under both protocols (median spatial F1 = 0.616, R^2 = 0.466); temporal expansion outperforms cross-city transfer, indicating city-scale representational drift. (2) Regression R^2 is driven primarily by zero/non-zero boundary discrimination: positive-pixel R^2 is consistently negative across all cities, revealing limited capacity to model intra-pixel density gradients at 10 m. (3) PC36 is consistently top-ranked across tasks; classification saturates at k = 32 while regression remains unsaturated at k = 64. (4) POI features yield the largest density gain (Delta R^2 = +0.064). (5) For six cities meeting dual-task usability thresholds, full-AOI inference across 2017-2024 preserves slum cluster structure (mean SSIM = 0.926). The study delineates the capabilities and complementarity needs of foundation-model embeddings for slum monitoring.

Medical image segmentation is a critical task in computer-aided diagnosis and treatment planning. However, deep learning models often struggle to generalize across datasets due to domain shifts arising from variations in imaging protocols, scanner types, and patient populations. Traditional domain generalization (DG) methods utilize causal feature learning, adversarial consistency, and style augmentation to improve segmentation robustness. While effective, these approaches rely on explicit feature alignment, adversarial objectives, or handcrafted augmentations, which may not fully exploit the capabilities of foundation models. Recently, the Segment Anything Model (SAM) has demonstrated strong generalization capabilities in segmentation tasks. SAM-based DG methods attempt to improve medical image segmentation. However, these approaches primarily operate in the spatial domain and overlook frequency-based discrepancies that significantly affect model robustness. In this work, we propose Frequency-based Domain Generalization with SAM (FSAM), a novel framework that integrates Low-Rank Adaptation (LoRA) for efficient fine-tuning and a frequency adapter to incorporate frequency-domain representations for single-source domain generalization. FSAM enhances SAM's segmentation robustness by extracting domain-invariant high-frequency features, mitigating frequency-related domain shifts. Experimental results on fundus and prostate datasets demonstrate that FSAM outperforms existing traditional DG and SAM-based DG approaches in domain generalization. Codes and pre-trained models will be made available on GitHub.

Class-Incremental Learning (CIL) requires a learning system to learn new classes while retaining previously learned knowledge. However, in real-world scenarios such as autonomous driving, a system trained on urban roads in sunny weather may later need to operate in rural or highway environments with different traffic patterns and weather conditions. This requires the model not only to overcome catastrophic forgetting, but also to effectively handle domain shifts. In this paper, we propose CrOss-sample Relational Fusion (CORF), a unified framework to address domain shift and catastrophic forgetting simultaneously. To enhance generalizability, we perform selective refinement of training samples by leveraging spatial contribution maps to highlight semantically informative regions. Furthermore, we incorporate predictive confidence to adaptively weigh samples, thereby facilitating the learning of domain-agnostic representations. To alleviate forgetting, we propose a cascaded distillation framework that captures cross-sample relational dependencies across multiple feature hierarchies, enabling multi-grained knowledge transfer from previous tasks. CORF can be seamlessly integrated into existing CIL algorithms to enhance their generalizability, achieving competitive performance across various benchmark datasets. Code is available at https://github.com/LAMDA-CL/TMM26-CORF .

We introduce BEACON--Best-Effort Adaptation for Cross-Domain Co-Training--a theory-driven framework for training generative robot policies with abundant source demonstrations and limited target demonstrations. BEACON casts cross-domain co-training as a discrepancy-aware importance-reweighting problem, jointly learning a diffusion-based visuomotor policy and per-sample source weights that minimize an objective informed by target-domain generalization guarantees. To make best-effort adaptation practical for high-dimensional sequence policies, we develop scalable instance-level discrepancy estimators, stochastic alternating updates for policy and weights, and a multi-source extension that balances heterogeneous source domains. Across sim-to-sim, sim-to-real, and multi-source manipulation settings, BEACON improves robustness and data efficiency over target-only, fixed-ratio co-training, and feature-alignment baselines. Importantly, even without an explicit alignment objective, BEACON achieves feature alignment as an implicit result of discrepancy-aware cross-domain co-training.

Vision-language models (VLMs) have advanced rapidly and are increasingly deployed in real-world applications, especially with the rise of agent-based systems. However, their safety has received relatively limited attention. Even the latest proprietary and open-weight VLMs remain highly vulnerable to adversarial attacks, leaving downstream applications exposed to significant risks. In this work, we propose a novel and lightweight adversarial attack detection framework based on sparse autoencoders (SAEs), termed SAEgis. By inserting an SAE module into a pretrained VLM and training it with standard reconstruction objectives, we find that the learned sparse latent features naturally capture attack-relevant signals. These features enable reliable classification of whether an input image has been adversarially perturbed, even for previously unseen samples. Extensive experiments show that SAEgis achieves strong performance across in-domain, cross-domain, and cross-attack settings, with particularly large improvements in cross-domain generalization compared to existing baselines. In addition, combining signals from multiple layers further improves robustness and stability. To the best of our knowledge, this is the first work to explore SAE as a plug-and-play mechanism for adversarial attack detection in VLMs. Our method requires no additional adversarial training, introduces minimal overhead, and provides a practical approach for improving the safety of real-world VLM systems.

Despite the growing popularity of Multimodal Domain Generalization (MMDG) for enhancing model robustness, it remains unclear whether reported performance gains reflect genuine algorithmic progress or are artifacts of inconsistent evaluation protocols. Current research is fragmented, with studies varying significantly across datasets, modality configurations, and experimental settings. Furthermore, existing benchmarks focus predominantly on action recognition, often neglecting critical real-world challenges such as input corruptions, missing modalities, and model trustworthiness. This lack of standardization obscures a reliable assessment of the field's advancement. To address this issue, we introduce MMDG-Bench, the first unified and comprehensive benchmark for MMDG, which standardizes evaluation across six datasets spanning three diverse tasks: action recognition, mechanical fault diagnosis, and sentiment analysis. MMDG-Bench encompasses six modality combinations, nine representative methods, and multiple evaluation settings. Beyond standard accuracy, it systematically assesses corruption robustness, missing-modality generalization, misclassification detection, and out-of-distribution detection. With 7, 402 neural networks trained in total across 95 unique cross-domain tasks, MMDG-Bench yields five key findings: (1) under fair comparisons, recent specialized MMDG methods offer only marginal improvements over ERM baseline; (2) no single method consistently outperforms others across datasets or modality combinations; (3) a substantial gap to upper-bound performance persists, indicating that MMDG remains far from solved; (4) trimodal fusion does not consistently outperform the strongest bimodal configurations; and (5) all evaluated methods exhibit significant degradation under corruption and missing-modality scenarios, with some methods further compromising model trustworthiness.

Domain generalization requires identifying stable representations that support reliable classification across domains. Domains may differ in low-level attributes, such as color, texture, or visual style, while preserving the same structural relationships among their underlying components. Existing methods primarily address these differences by improving the training process or aligning features across domains. However, since they leave this shared compositional structure implicit, they may overlook a more reliable source of invariance and consequently generalize less effectively to unseen domains. We propose Compositional Relational Invariance from Spatial Primitives (CRISP), an image classification framework that factors visual recognition into visual primitives and their relational composition. We represent these compositions using soft unary, binary, and ternary predicates over primitive locations and appearance, yielding differentiable measures of spatial and visual alignment that can be learned end-to-end. To learn primitives and relational structure jointly, we design an end-to-end architecture with three components: (1) a visual backbone that extracts generalized features, (2) a concept bottleneck layer that maps these features to primitive heatmaps with differentiable spatial coordinates, and (3) a structural scoring layer that evaluates candidate spatial relations among the detected primitives. Finally, we compute class probability from the joint evidence of its class-specific relational compositions and localized primitive appearance. We evaluate \method{} on five real-world image-classification datasets from the widely used DomainBed suite, covering shifts in depiction style, dataset provenance, and camera-trap location and achieving the new state-of-the-art on both benchmarks.

Domain Generalization (DG) aims to learn representations that remain robust under out-of-distribution (OOD) shifts and generalize effectively to unseen target domains. While recent invariant learning strategies and architectural advances have achieved strong performance, explicitly discovering a structured domain-invariant subspace through second-order statistics remains underexplored. In this work, we propose CPCANet, a novel framework grounded in Common Principal Component Analysis (CPCA), which unrolls the iterative Flury-Gautschi (FG) algorithm into fully differentiable neural layers. This approach integrates the statistical properties of CPCA into an end-to-end trainable framework, enforcing the discovery of a shared subspace across diverse domains while preserving interpretability. Experiments on four standard DG benchmarks demonstrate that CPCANet achieves state-of-the-art (SOTA) performance in zero-shot transfer. Moreover, CPCANet is architecture-agnostic and requires no dataset-specific tuning, providing a simple and efficient approach to learning robust representations under distribution shift. Code is available at https://github.com/wish44165/CPCANet.

Lifelong person re-identification (LReID) aims to train a generalizable model with sequentially collected data. However, such models often suffer from semantic drift, limited adaptability, and catastrophic forgetting as new domains emerge. Existing exemplar-free approaches largely rely on visual-only distillation or parameter regularization, while overlooking the potential of auxiliary modalities, such as text, to preserve semantic stability and enable incremental plasticity. We observe that the frozen text encoder in pretrained vision-language models can serve as a stable semantic anchor across domains. To decouple the roles of vision and text, we propose Prompt-Anchored vision-text Distillation (PAD), an asymmetric vision-text framework for semantic alignment and cross-domain generalization. On the textual side, we distill prompts to preserve vision-text alignment under a fixed semantic space, acting as a global semantic reference rather than a dominant learning signal. On the visual side, an EMA-based teacher with an adaptive prompt pool enables domain-wise adaptation by allocating new slots while freezing past ones. Extensive experiments show that PAD substantially outperforms state-of-the-art methods across seen and unseen domains, achieving a strong balance between stability and plasticity. Project page is available at https://github.com/zu-zi/PAD.

Mechanical equipment forms the critical backbone of modern industrial production, yet domain shift severely limits the generalization of deep learning based fault diagnosis models across different equipment and operating conditions.Inspired by the success of foundation models in achieving zero-shotgeneralization, we propose YOTOnet (You Only Train Once), a novel architecture specifically designed for cross-domain fault diagnosis in mechanical equipment.YOTOnet comprises three core components: (1) a physics-aware Invariant Feature Distiller that extracts domain-agnostic representations using multi-scale dilated convolutions and FFT-based time-frequency fusion,(2) Domain-Conditioned Sparse Experts (DC-MoE) that adaptively route inputs to specialized processors via learned gating without external meta-data, and (3) a dual-head classification system with auxiliary supervision.Extensive validation on five public bearing datasets (CWRU, MFPT, XJTU,OTTAWA, HUST) through 30 cross-dataset protocols demonstrates the superiority of YOTOnet compared with other state-of-the-art methods. Critically, we observe a clear scaling effect-average test F1 improves from 0.5339(1 training dataset) to 0.705 (4 datasets), with a clear gain when moving from 3 to 4 datasets. These findings provide empirical evidence that foundation model principles can enable robust, train-once deployment for industrial fault diagnosis.

Low-resource language varieties used by specific groups remain neglected in the development of Multilingual Language Models. A great deal of cross-lingual research focuses on inter-lingual language transfer which strives to align allied varieties and minimize differences between them. However, for low-resource varieties, linguistic dissimilarity is also an important cue allowing generalization to unseen varieties. Unlike prior approaches, we propose a two-stage Language Generalization framework that focuses on capturing variety-specific cues while also exploiting rich overlap offered by high-resource source variety. First, we propose TOPPing, a source-selection method specifically designed for low-resource varieties. Second, we suggest a lightweight VACAI-Bowl architecture that learns variety-specific attributes with one branch while a parallel branch captures variety-invariant attributes using adversarial training. We evaluate our framework on structural prediction tasks, which are among the few tasks available, as proxy for performance on other downstream tasks. Using VACAI-Bowl with TOPPing yields an average 54.62% improvement in the dependency parsing task, which serves as a proxy for performance on other downstream tasks across 10 low-resource varieties.

Deploying multimodal models in real-world scenarios requires generalization to new environments where recording conditions differ from training, a challenge known as multimodal domain generalization (MMDG). Standard architectures employ separate encoders for each modality and a fusion module, training the system end-to-end by optimizing on the fused features. In this paper, we identify that such joint optimization causes encoders to exploit cross-modal co-occurrences, statistical relationships between modalities that arise from source-specific recording conditions, rather than learning domain-invariant features. We term this failure mode Fusion Overfitting. To address this, we propose Modality-Entropy Regularization for Domain Generalization (MER-DG), which maximizes the entropy of each encoder's feature distribution to preserve feature diversity. MER-DG is architecture-agnostic and integrates into existing multimodal frameworks as an additive loss term. Extensive experiments on EPIC-Kitchens and HAC benchmarks demonstrate average improvements of approximately 5% over standard fusion and approximately 2% over state-of-the-art methods.

Given the rapidly growing capabilities of vision-language models (VLMs), extending them to interactive decision-making tasks such as video games has emerged as a promising frontier. However, existing approaches either rely on large-scale supervised fine-tuning (SFT) on human trajectories or apply reinforcement learning (RL) only in relatively short-horizon settings (typically around 20--30 turns). In this work, we study RL-based training of VLMs for long-horizon decision-making in Super Mario Land, a visually grounded environment requiring 100+ turns of interaction with coordinated perception, reasoning, and action. We begin with a systematic investigation of key algorithmic components and propose an adapted variant of PPO with a lightweight turn-level critic, which substantially improves training stability and sample efficiency over critic-free methods such as GRPO and Reinforce++. We further show that pretrained VLMs provide strong action priors, significantly improving sample efficiency during RL training and reducing the need for manual design choices such as action engineering, compared to classical deep RL trained from scratch. Building on these insights, we introduce Odysseus, an open training framework for VLM agents, achieving substantial gains across multiple levels of the game and at least 3 times average game progresses than frontier models. Moreover, the trained models exhibit consistent improvements under both in-game and cross-game generalization settings, while maintaining general-domain capabilities. Overall, our results identify key ingredients for making RL stable and effective in long-horizon, multi-modal settings, and provide practical guidance for developing VLMs as embodied agents.

Integrating domain knowledge into deep neural networks is a promising way to improve generalization. Existing methods either encode prior knowledge in the loss function or apply post-processing modules, but both depend on identifying useful symbolic knowledge to integrate. Since such rules are often unavailable in real-world vision tasks, we propose a method for targeted knowledge discovery. We propose a Differentiable Knowledge Unit (DKU) that enables modulating the classifier logits, yielding refined class probabilities. The DKU uses implication rules to represent relationships between task classes and implicit concepts learned entirely from the main task supervision, without requiring concept labels. Concepts are identified by dedicated classifiers, whose probabilities are passed to DKU alongside the primary class probabilities. DKU computes a logic-based adjustment vector via fuzzy inference, which modulates the primary class logits to yield refined class probabilities. When concept classifiers represent concepts that do not support the logical rule structure, the resulting adjustments to the class probabilities do not directly minimize the supervision loss. Consequently, optimizing the supervision loss on these adjusted class probabilities implicitly trains the concept classifiers. We construct the rule base so that bidirectional logical relations connect concepts and classes. We enforce the concepts to be distinct from each other and with respect to the classes. This design enforces a clean supervision signal for concept learning. We evaluate our methods on the PASCAL-VOC, COCO, and MedMNIST datasets. We demonstrate improvement through our knowledge integration across these datasets. We conduct domain generalization and hard-sample ablation studies and find that our implicit knowledge discovery and integration outperforms the baseline.

Detectors often suffer from degraded performance, primarily due to the distributional gap between the source and target domains. This issue is especially evident in single-source domains with limited data, as models tend to rely on confounders (e.g., illumination, co-occurrence, and style) from the source domain, leading to spurious correlations that hinder generalization. To this end, this paper proposes a novel Basis-driven framework for domain generalization, namely \textbf{\textit{Bridge}}, that incorporates causal inference into object detection. By learning the low-rank bases for front-door adjustment, \textbf{\textit{Bridge}} blocks confounders' effects to mitigate spurious correlations, while simultaneously refining representations by filtering redundant and task-irrelevant components. \textbf{\textit{Bridge}} can be seamlessly integrated with both discriminative (e.g., DINOv2/3, SAM) and generative (e.g., Stable Diffusion) Vision Foundation Models (VFMs). Extensive experiments across multiple domain generalization object detection datasets, i.e., Cross-Camera, Adverse Weather, Real-to-Artistic, Diverse Weather Datasets, and Diverse Weather DroneVehicle (our newly augmented real-world UAV-based benchmark), underscore the superiority of our proposed method over previous state-of-the-art approaches. The project page is available at: https://mingbohong.github.io/Bridge/.

Federated domain generalization for person re-identification (FedDG-ReID) aims to collaboratively train a pedestrian retrieval model across multiple decentralized source domains such that it can generalize to unseen target environments without compromising raw data privacy. However, this task is significantly challenged by the inherent stylistic gaps across decentralized clients. Without global supervision, models easily succumb to shortcut learning where representations overfit to domain specific camera biases rather than universal identity features. We propose CO-EVO, a novel federated framework that resolves this semantic-style conflict through a co-evolutionary mechanism. On the semantic side, Camera-Invariant Semantic Anchoring (CSA) learns identity prompts with cross-camera consistency to establish purified and domain-agnostic anchors that filter out local imaging noise. On the visual side, Global Style Diversification (GSD), powered by a Global Camera-Style Bank (GCSB), synthesizes realistic perturbations to expand the visual boundaries of training data. The core of CO-EVO is its co-evolutionary loop where purified anchors act as gravitational centers to guide the image encoder toward robust anatomical attributes amidst diverse style variations. Extensive experiments demonstrate that CO-EVO achieves state-of-the-art (SOTA) performance, proving that the synergy between semantic purification and style expansion is essential for robust cross-domain generalization. Our code is available at: https://github.com/NanYiyuzurn/ACL-LGPS-2026.

Exploiting deep learning in medical imaging faces critical challenges, including strict privacy constraints, heterogeneous imaging devices with varying acquisition properties, and class imbalance due to the uneven prevalence of pathologies. In this work, we propose FedSSG, a novel Federated Learning framework that addresses domain shifts caused by diverse imaging devices while mitigating the under-representation of rare pathologies. The key contribution is a strategy for generating synthetic samples and distributing them across clients to improve coverage of both underrepresented pathologies and imaging devices. Experimental results demonstrate that our approach significantly enhances model performance and generalization across heterogeneous institutions, with minimal computational overhead at the client side.

Magnification shift is a major obstacle to robust histopathology classification, because models trained on one imaging scale often generalize poorly to another. Here, we evaluated this problem on the BreaKHis dataset using a strict patient-disjoint leave-one-magnification-out protocol, comparing supervised baseline, baseline augmented with DCGAN-generated patches, and a gradient-reversal domain-general model designed to preserve discriminative information while suppressing magnification-specific variation. Across held-out magnifications, the domain-general model achieved the strongest overall discrimination and its clearest gain was observed when 200X was held out. By contrast, GAN augmentation produced inconsistent effects, improving some folds but degrading others, particularly at 400X. The domain-general model also yielded the lowest Brier score at 0.063 vs 0.089 at baseline. Sparse embedding analysis further revealed that domain-general training reduced average signature size more than three-fold (306 versus 1,074 dimensions) while preserving equivalent predictive performance (AUC: 0.967 vs 0.965; F1: 0.930 vs 0.931). It also increased cross-fold signature reproducibility from near-zero Jaccard overlap in the baseline to 0.99 between the 100X and 200X folds. These findings show that calibrated, compact, and transferable representations can be learned without added architectural complexity, with clear implications for the reliable deployment of computational pathology models across heterogeneous acquisition settings.

Vision-language-action (VLA) models have shown strong semantic grounding and task generalization in manipulation, but aerial deployment remains difficult because drones require low-latency closed-loop guidance under strict onboard compute and communication constraints. We present LiteVLA-H, a compact 256M-parameter VLA system designed for dual-rate operation on an NVIDIA Jetson AGX Orin: a fast outer-loop guidance mode for short action-token outputs and a slower semantic mode for scene understanding, hazard description, and operator-facing narration. The central empirical observation is that, in this compact edge regime, end-to-end latency is dominated by multimodal pre-fill rather than by the marginal cost of decoding a few extra tokens. This motivates a scheduler that issues reactive action tokens at 50.65,ms (19.74,Hz) while still supporting sentence-level semantic outputs at 149.90--164.57\ms (6.08--6.67,Hz) on the same embedded platform. To specialize the model without collapsing its descriptive competence, we use a knowledge-preserving fine-tuning recipe that mixes reactive flight data, aerial semantic data, and generic caption/VQA supervision. Beyond reporting current latency measurements, we position the system against recent state-of-the-art architectures, including AnywhereVLA, FutureVLA, and ReMem-VLA, showing that the measured action branch reaches a higher edge inference rate under our deployment conditions while retaining periodic semantic awareness.

Fault diagnosis under unseen operating conditions remains highly challenging when labeled data are scarce. Semi-supervised domain generalization fault diagnosis (SSDGFD) provides a practical solution by jointly exploiting labeled and unlabeled source domains. However, existing methods still suffer from two coupled limitations. First, pseudo-labels for unlabeled domains are typically generated primarily from knowledge learned on the labeled source domain, which neglects domain-specific geometric discrepancies and thus induces systematic cross-domain pseudo-label bias. Second, unlabeled samples are commonly handled with a hard accept-or-discard strategy, where rigid thresholding causes imbalanced sample utilization across domains, while hard-label assignment for uncertain samples can easily introduce additional noise. To address these issues, we propose a unified framework termed domain-aware hierarchical contrastive learning (DAHCL) for SSDGFD. Specifically, DAHCL introduces a domain-aware learning (DAL) module to explicitly capture source-domain geometric characteristics and calibrate pseudo-label predictions across heterogeneous source domains, thereby mitigating cross-domain bias in pseudo-label generation. In addition, DAHCL develops a hierarchical contrastive learning (HCL) module that combines dynamic confidence stratification with fuzzy contrastive supervision, enabling uncertain samples to contribute to representation learning without relying on unreliable hard labels. In this way, DAHCL jointly improves the quality of supervision and the utilization of unlabeled samples. Furthermore, to better reflect practical industrial scenarios, we incorporate engineering noise into the SSDGFD evaluation protocol. Extensive experiments on three benchmark datasets demonstrate that...

The combination of Mixture-of-Experts (MoE) and Low-Rank Adaptation (LoRA) has shown significant potential for enhancing the multi-task learning capabilities of Large Language Models. However, existing methods face two primary challenges: (1)Imprecise Routing in the current MoE-LoRA method fails to explicitly match input semantics with expert capabilities, leading to weak expert specialization. (2)Uniform weight fusion strategies struggle to provide adaptive update strengths, overlooking the varying complexity of different tasks. To address these limitations, we propose SAMoRA (Semantic-Aware Mixture of LoRA Experts), a novel parameter-efficient fine-tuning framework tailored for task-adaptive learning. Specifically, A Semantic-Aware Router is proposed to explicitly align textual semantics with the most suitable experts for precise routing. A Task-Adaptive Scaling mechanism is designed to regulate expert contributions based on specific task requirements dynamically. In addition, a novel regularization objective is proposed to jointly promote expert specialization and effective scaling. Extensive experiments on multiple multi-task benchmarks demonstrate that SAMoRA significantly outperforms the state-of-the-art methods and holds excellent task generalization capabilities. Code is available at https://github.com/boyan-code/SAMoRA

Automatic pancreas segmentation is fundamental to abdominal MRI analysis, yet deep learning models trained on one MRI sequence often fail catastrophically when applied to another-a challenge that has received little systematic investigation. We introduce CrossPan, a multi-institutional benchmark comprising 1,386 3D scans across three routinely acquired sequences (T1-weighted, T2-weighted, and Out-of-Phase) from eight centers. Our experiments reveal three key findings. First, cross-sequence domain shifts are far more severe than cross-center variability: models achieving Dice scores above 0.85 in-domain collapse to near-zero (<0.02) when transferred across sequences. Second, state-of-the-art domain generalization methods provide negligible benefit under these physics-driven contrast inversions, whereas foundation models like MedSAM2 maintain moderate zero-shot performance through contrast-invariant shape priors. Third, semi-supervised learning offers gains only under stable intensity distributions and becomes unstable on sequences with high intra-organ variability. These results establish cross-sequence generalization-not model architecture or center diversity-as the primary barrier to clinically deployable pancreas MRI segmentation. Dataset and code are available at https://crosspan.netlify.app/.

Machine learning (ML) models trained to detect physical-layer threats on one optical fiber system often fail catastrophically when applied to a different system, due to variations in operating wavelength, fiber properties, and network architecture. To overcome this, we propose a Domain Adaptation (DA) framework based on a Variational Autoencoder (VAE) that learns a shared representation capturing event signatures common to both systems while suppressing system-specific differences. The shared encoder is first trained on the combined data from two distinct optical systems: a 21 km O-band dark-fiber testbed (System 1) and a 63.4 km C-band live metro ring (System 2). The encoder is then frozen, and a classifier is trained using labels from an individual system. The proposed approach achieves 95.3% and 73.5% cross-system accuracy when moving from System 1 to System 2 and vice versa, respectively. This corresponds to gains of 83.4% and 51% over a fully supervised Deep Neural Network (DNN) baseline trained on a single system, while preserving intra-system performance.

Pretrained biomedical vision-language models (VLMs) such as BioMedCLIP perform well on average but often degrade on challenging modalities where inter-class margins are small and acquisition-specific variations are pronounced, especially under few-shot supervision and when modality priors differ from pretraining corpora substantially. We propose BioVLM, a prompt-learning framework that improves cross-domain generalization without extensive backbone fine-tuning. BioVLM learns a diverse prompt bank and introduces dynamic prompt selection: for each input, it selects the most discriminative prompts via a low-entropy criterion on the predictive distribution, effectively coupling sparse few-shot evidence with rich LLM semantic priors. To strengthen this coupling, we distill high-confidence LLM-derived attributes and enforce robust knowledge transfer through strong/weak augmentation consistency. At test time, BioVLM adapts by choosing modality-appropriate prompts, enabling transfer to unseen categories and domains, while keeping training lightweight and inference efficient. On 11 MedMNIST+ 2D datasets, BioVLM achieves new state of the art across three distinct generalization settings. Codes are available at https://github.com/mainaksingha01/BioVLM.

Domain generalization (DG) aims to maintain performance under domain shift, which in computer vision appears primarily as stylistic variations that cause models to overfit to domain-specific appearance cues rather than class semantics. To overcome this, recent methods use textual representations as stable, domain-invariant anchors. However, multimodal approaches that rely on cosine similarity-based contrastive alignment leave a modality gap where image and text embeddings remain geometrically separated despite semantic correspondence. We propose CrossFlowDG, a novel DG framework that addresses this residual gap using noise-free, cross-modal flow matching. By learning a continuous transformation in the joint Euclidean latent space, our framework explicitly transports domain-biased image embeddings toward domain-invariant text embeddings of the correct class. Using the efficient VMamba image encoder and CLIP's text encoder, CrossFlowDG is tested against four common DG benchmarks, and achieves competitive performance on several benchmarks and state-of-the-art on TerraIncognita. Code is available at: https://github.com/ajkrit/CrossFlowDG

Generalizable gaze estimation methods have garnered increasing attention due to their critical importance in real-world applications and have achieved significant progress. However, they often overlook the effect of label noise, arising from the inherent difficulty of acquiring precise gaze annotations, on model generalization performance. In this paper, we are the first to comprehensively investigate the negative effects of label noise on generalization in gaze estimation. Further, we propose a novel solution, called See-Through-Noise (SeeTN) framework, which improves generalization from a novel perspective of mitigating label noise. Specifically, we propose to construct a semantic embedding space via a prototype-based transformation to preserve a consistent topological structure between gaze features and continuous labels. We then measure feature-label affinity consistency to distinguish noisy from clean samples, and introduce a novel affinity regularization in the semantic manifold to transfer gaze-related information from clean to noisy samples. Our proposed SeeTN promotes semantic structure alignment and enforces domain-invariant gaze relationships, thereby enhancing robustness against label noise. Extensive experiments demonstrate that our SeeTN effectively mitigates the adverse impact of source-domain noise, leading to superior cross-domain generalization without compromising the source-domain accuracy, and highlight the importance of explicitly handling noise in generalized gaze estimation.

Out-of-distribution (OOD) detection remains a critical challenge in open-world learning, where models must adapt to evolving data distributions. While recent vision-language models (VLMS) like CLIP enable multimodal OOD detection through Dual-Pattern Matching (DPM), existing methods typically suffer from two major shortcomings: (1) They rely on fixed fusion rules and assume static environments, failing under temporal drift; and (2) they lack robustness against covariate shifted inputs. In this paper, we propose a novel two-step framework to enhance OOD detection and covariate distribution shift robustness in dynamic settings. We extend the dual-pattern regime into Temporal Quadruple-Pattern Matching (T-QPM). First, by pairing OOD images with text descriptions, we introduce cross-modal consistency patterns between ID and OOD signals, refining the decision boundary through joint image-text reasoning. Second, we address temporal distribution shifts by learning lightweight fusion weights to optimally combine semantic matching and visual typicality. To ensure stability, we enforce explicit regularization based on Average Thresholded Confidence (ATC), preventing performance degradation as distributions evolve. Experiments on temporally partitioned benchmarks demonstrate that our approach significantly outperforms static baselines, offering a robust, temporally-consistent framework for multimodal OOD detection in non-stationary environments.

We propose a novel swap-adversarial framework that mitigates high inter-subject variability and the high-dimensional low-sample-size problem in electrocorticography (ECoG) data. It achieves robust domain generalization across ECoG and electroencephalography (EEG)-based brain-computer interface datasets. Our framework integrates (1) robust preprocessing, (2) inter-subject balanced channel swap (ISBCS) for cross-subject augmentation, and (3) domain-adversarial learning (DAL) to suppress subject-specific bias. The ISBCS method is a bio-inspired channel swapping strategy that exchanges only functionally corresponding channels across subjects, guided by a brain map, to mitigate inter-subject distribution differences. The DAL strategy encourages the model to learn task-relevant shared features. We validate the effectiveness of this framework through extensive experiments under cross-subject, cross-session, and cross-dataset settings. Our framework consistently outperforms all baselines across all settings, showing the most significant improvements in highly variable environments. It also achieves superior cross-dataset performance between public EEG benchmarks, demonstrating strong generalization capability not only for ECoG but also for EEG data. In addition, we introduce a new ECoG dataset, the first reproducible benchmark, which is constructed from long-term ECoG recordings of 6-hydroxydopamine-induced rat models and annotated with neural responses measured before and after electrical stimulation.

As many benchmarks have become saturated, it has become increasingly important to create new datasets that evaluate the generalization capacity of current state-of-the-art models in reasoning. However, designing high-quality reasoning datasets is challenging, as their manual construction is costly, and their automatic generation is unreliable, often leading to synthetic data with limited scope. In this paper, we propose the Minimal Expression-Replacement GEneralization (MERGE) test that evaluates the robustness of reasoning models against non-adversarial variants of existing evaluation datasets. We automatically obtain high-quality variants from the original instances with Minimal Expression REplacement (MERE) generation, which uses Masked Language Models (MLMs) and safeguarding filters. We apply the MERGE test to Natural Language Inference (NLI), a popular task of reasoning. We generate new NLI datasets from two widely used existing ones with the MERE generation and use them to evaluate multiple strong NLI models. The results indicate that both LLMs and fine-tuned NLI models generalize poorly: they struggle to consistently and correctly classify variants minimally different in form and reasoning from the original ones. Further, we also analyze how certain aspects in variant generation, such as the word class and the source MLMs, affect model performance.

Domain generalization has become a critical challenge in predictive healthcare, where different patient groups exhibit shifting data distributions that degrade model performance. Still, regular domain generalization approaches often struggle in clinical settings due to (1) the absence of domain labels and (2) the lack of clinical insight integration. To address these challenges in healthcare, we aim to explore how medical ontologies can be used to discover dynamic yet hierarchy-grounded patient domains, a partitioning strategy that remains under-explored in prior work. Hence, we introduce UdonCare, a hierarchy-pruning method that iteratively divides patients into latent domains and retrieves domain-invariant (label) information from patient data. On public datasets (MIMIC-III, MIMIC-IV, and eICU), UdonCare shows superiority over eight generalization baselines across four representative clinical prediction tasks with substantial domain gaps, highlighting the potential of medical knowledge for enhancing model generalization.

Face Anti-Spoofing (FAS) is essential for the security of facial recognition systems in diverse scenarios such as payment processing and surveillance. Current multimodal FAS methods often struggle with effective generalization, mainly due to modality-specific biases and domain shifts. To address these challenges, we introduce the \textbf{M}ulti\textbf{m}odal \textbf{D}enoising and \textbf{A}lignment (\textbf{MMDA}) framework. By leveraging the zero-shot generalization capability of CLIP, the MMDA framework effectively suppresses noise in multimodal data through denoising and alignment mechanisms, thereby significantly enhancing the generalization performance of cross-modal alignment. The \textbf{M}odality-\textbf{D}omain Joint \textbf{D}ifferential \textbf{A}ttention (\textbf{MD2A}) module in MMDA concurrently mitigates the impacts of domain and modality noise by refining the attention mechanism based on extracted common noise features. Furthermore, the \textbf{R}epresentation \textbf{S}pace \textbf{S}oft (\textbf{RS2}) Alignment strategy utilizes the pre-trained CLIP model to align multi-domain multimodal data into a generalized representation space in a flexible manner, preserving intricate representations and enhancing the model's adaptability to various unseen conditions. We also design a \textbf{U}-shaped \textbf{D}ual \textbf{S}pace \textbf{A}daptation (\textbf{U-DSA}) module to enhance the adaptability of representations while maintaining generalization performance. These improvements not only enhance the framework's generalization capabilities but also boost its ability to represent complex representations. Our experimental results on four benchmark datasets under different evaluation protocols demonstrate that the MMDA framework outperforms existing state-of-the-art methods in terms of cross-domain generalization and multimodal detection accuracy. The code will be released soon.

Few-shot action recognition (FSAR) aims to recognize novel action categories with few exemplars. Existing methods typically learn frame-level representations for each video by designing inter-frame temporal modeling strategies or inter-video interaction at the coarse video-level granularity. However, they treat each episode task in isolation and neglect fine-grained temporal relation modeling between videos, thus failing to capture shared fine-grained temporal patterns across videos and reuse temporal knowledge from historical tasks. In light of this, we propose HR2G-shot, a Hierarchical Relation-augmented Representation Generalization framework for FSAR, which unifies three types of relation modeling (inter-frame, inter-video, and inter-task) to learn task-specific temporal patterns from a holistic view. Going beyond conducting inter-frame temporal interactions, we further devise two components to respectively explore inter-video and inter-task relationships: i) Inter-video Semantic Correlation (ISC) performs cross-video frame-level interactions in a fine-grained manner, thereby capturing task-specific query features and enhancing both intra-class consistency and inter-class separability; ii) Inter-task Knowledge Transfer (IKT) retrieves and aggregates relevant temporal knowledge from the bank, which stores diverse temporal patterns from historical episode tasks. Extensive experiments on five benchmarks show that HR2G-shot outperforms current top-leading FSAR methods.