Multiscale Time-Series Modeling

Modeling long-sequence medical time series data, such as electrocardiograms (ECG), poses significant challenges due to high sampling rates, multichannel signal complexity, inherent noise, and limited labeled data. While recent self-supervised learning (SSL) methods, based on various encoder architectures such as convolutional neural networks, have been proposed to learn representations from unlabeled data, they often fall short in capturing long-range dependencies and noise-invariant features. Structured state space models (S4) excel at long-sequence modeling, but existing S4 architectures fail to capture the unique characteristics of multichannel physiological waveforms. In this work, we propose SL-S4Wave, a self-supervised learning framework that combines contrastive learning with a tailored encoder built on structured state space models. The encoder incorporates multi-layer global convolution using multiscale subkernels, enabling the capture of both fine-grained local patterns and long-range temporal dependencies in noisy, high-resolution multichannel waveforms. Extensive experiments on real-world datasets demonstrate that SL-S4Wave (1) consistently outperforms state-of-the-art supervised and self-supervised baselines in a challenging arrhythmia detection task, (2) achieves high performance with significantly fewer labeled examples, showcasing strong label efficiency, and (3) maintains robust performance on long waveform segments, highlighting its capacity to model complex temporal dynamics in long sequences that most existing approaches fail to efficiently model, and (4) transfers effectively to unseen arrhythmia types, underscoring its robust cross-domain generalization. We additionally evaluate SL-S4Wave on multiple EEG tasks, achieving superior performance over strong baselines, demonstrating generalizability of our approach beyond cardiac waveforms.

Molecular dynamics (MD) simulation is computationally demanding, particularly for large-scale systems requiring long-term analysis. Accurate forecast of the outcomes of a MD simulation is not only an attractive scientific challenge but also has substantial practical value. In this work, we developed a data-driven framework, termed ASTEROID (Advanced Spatiotemporal TransformER fOr Inferring Dynamics), that can directly predict multi-step atomic coordinates, avoiding conventional iterative integration. For this purpose, our ASTEROID reformulates MD trajectories as high-dimensional spatiotemporal sequences and integrates the Spatiotemporal Information (STI) Transformation equation into a Transformer architecture. The core innovation of ASTEROID lies in its ability to model multiscale spatiotemporal dependencies. In particular, for spatial dependencies, a local-global self-attention mechanism captures both short- and long-range interactions. For temporal dependencies, an encoder-decoder structure integrates global context with autoregressive forecasting. ASTEROID was evaluated on several quantum-mechanics derived molecular datasets. Our results indicate that ASTEROID achieved not only a higher level of accuracy in multi-step prediction than existing methods on various benchmarks, but also significantly reduced computational cost of conventional MD simulation. Moreover, the model supports iterative multi-step forecasting over an extended time scale. This work establishes a robust and generalizable data-driven paradigm for accelerating MD simulations.

Spoofed speech detection is increasingly challenged by realistic synthesis, voice conversion, and replay attacks, with cross-dataset generalization remaining a major limitation. This work we propose a Temporal Pyramid Adapter that utilize parallel temporal convolutions with varying receptive fields to capture multi-scale spoofing cues, ranging from local artifacts to global prosodic irregularities. We also integrated self-supervised XLS-R representations combined with front-end adapters, including Mel, Sinc, and a Temporal Pyramid design for multi-scale temporal modeling. The proposed model is evaluated cross multiple benchmark including ASVspoof 2017, ASVspoof 2021 (DF/LA), PartialSpoof, DiffSSD, and multilingual HQ-MPSD datasets. Experimental results demonstrate that Temporal Pyramid model obtained AUC of 99.24% and a EER of 3.87% on the PartialSpoof database, which is significantly outperforming the base model and several SOTA baseline such as LCNN-BLSTM (9.87% EER) and TRACE (8.08% EER). Additionally, multilingual evaluations confirm that while spoofing artifact are independent from language. While self-supervised representations improve robustness, performance degrades under domain and language shifts, highlighting the need for better adaptation and calibration strategies.

Spatio-Temporal forecasting is crucial in diverse fields, such as transportation, climate, and energy. Urban spatio-temporal data exhibits temporal mirage: similar short-window inputs have divergent future trends, and vice versa. Existing spatio-temporal graph neural networks (STGNNs) cannot effectively identify such mirages. We argue that the core reason lies in the short-window inputs that have incomplete period observation, heterogeneous global spatial correlation, and cross-period superposition causality. To bridge this gap, we develop a novel Multi- Period Pattern Pre-training (MP3), a plug-and-play pre-training plugin for distinguishing temporal mirages. MP3 presents two core innovations: (1) The multi-period pattern learning is designed to learn multi-period patterns from long time series. Specifically, multi-period temporal modeling leverages edge convolution to identify different multi-period patterns. Multi-period spatial modeling uses a bottleneck project and a global memory bank to capture heterogeneous global spatial relations efficiently. Cross-period pattern interaction employs a causality-enhanced Transformer to capture dependencies across different period patterns. (2) This plugin can seamlessly integrate into existing STGNN backbones to strengthen their forecasting performance. The experiment on five STGNN baselines across five real-world datasets (including a large-scale dataset CA) verify the effectiveness, superior scalability and strong adaptability of MP3, which brings consistent and robust performance improvements across all evaluated baselines. On average, MP3 reduces the MAE 4.7% and the RMSE 5.0%. The code can be available at https://github.com/YAN-outlook/MP3.

Multivariate time-series data often exhibit complex temporal dependencies, irregular sampling, and heterogeneous dynamics across multiple time scales, making accurate sequence modeling particularly challenging. Traditional recurrent neural networks (RNNs), such as Long Short-Term Memory (LSTM) networks, operate in discrete time and may struggle to effectively capture continuous and irregular temporal behaviors. Liquid Neural Networks (LNNs) address some of these limitations through continuous-time dynamics, but standard LNN architectures typically rely on a single dynamical system, limiting their ability to model heterogeneous temporal patterns. To address these challenges, we propose a Multi-Rate Mixture-of-Experts (MR-MoE) framework built on top of Liquid Neural Networks. In the proposed architecture, multiple LNN-based experts operate at distinct time scales, enabling the model to explicitly separate fast-changing dynamics from slow-evolving temporal trends. A gating network further enables adaptive expert specialization based on input conditions. In addition, we incorporate both feature-level and temporal attention mechanisms to improve robustness, interpretability, and long-range dependency modeling. Feature-level attention suppresses noisy or irrelevant variables, while temporal attention selectively focuses on informative historical states. We evaluate the proposed framework on a complex multivariate time-series prediction task and compare it against strong baselines, including LSTM, monolithic LNN, and standard MoE models. Experimental results demonstrate that the proposed MR-MoE framework consistently achieves improved AUROC and AUPRC performance while maintaining favorable computational efficiency. These results highlight the effectiveness of combining continuous-time dynamics, multi-scale expert decomposition, and adaptive attention mechanisms for time-series modeling.

Transformer-based models have emerged as leading paradigms in time-series forecasting in recent years, employing self-attention mechanisms to capture long-range dependencies. Despite their success, these single-stage forecasting architectures exhibit persistent systematic residual biases arising from structural discrepancies, unmodeled stochastic components, or inadequate multi-scale temporal representations. This limitation persists when residuals are treated as irreducible noise, precluding adaptive correction of structured error patterns. To address this limitation, we introduce a two-stage, model-agnostic framework that explicitly decouples forecasting and residual learning into distinct stages of representation learning. A base transformer first generates the initial predictions. Subsequently, a dedicated meta-corrector dynamically models structured error patterns across multivariate channels, preserves cross-variable dependencies, and iteratively refines the residual bias of the base transformer. By formalizing this pipeline as a hypothesis space expansion, our framework addresses approximation limitations inherent in single-stage architectures, removes reliance on restrictive assumptions, and enables end-to-end learning of complex error dynamics. Evaluated on eight popular benchmark datasets using established protocols, our approach achieves state-of-the-art performance, with significant improvements in standard metrics (MSE, MAE). The results demonstrate the framework's ability to mitigate systematic biases and enhance robustness to complex temporal dynamics, advancing the practical applicability of transformer-based forecasting models.

Efficient acquisition, storage, and utilization of traffic data are critical challenges in spatio-temporal data management. Most traffic data systems collect and store observations at fixed, coarse-grained temporal intervals to reduce storage and computation costs. However, such coarse-grained data severely limits downstream applications that require predictions at a finer temporal granularity. Collecting and maintaining fine-grained traffic data across all locations and time periods would impose a substantial burden on database storage and preprocessing pipelines. To address this temporal granularity mismatch, we formulate a novel problem: predicting fine-grained future traffic using coarse-grained sampled data. We propose the Spatial-Temporal Refinement Predictor (STRP), a granularity-aware framework for spatio-temporal data systems. STRP integrates two components: Tree Convolution for efficient and interpretable spatial dependency modeling, and Inverse Dilated Convolution for progressive temporal extrapolation. STRP supports two practical prediction settings: window-based and duration-based, to handle different forms of granularity mismatch. Experiments on six benchmark datasets show that STRP significantly outperforms state-of-the-art baselines in both accuracy and efficiency. Our work offers a practical and interpretable approach to managing granularity mismatches in spatio-temporal traffic data systems.

This study presents a comprehensive field validation of a multi-resolution Convolutional Long Short-Term Memory (ConvLSTM) framework for predicting retaining wall deformation during staged excavation. The framework is trained on Gaussian noise-augmented numerical simulations and integrates ConvLSTM models operating at different temporal resolutions through a stacking ensemble strategy. The proposed framework is validated using field monitoring data from 34 inclinometers across 11 excavation sites in South Korea. Site-wise prediction performance is systematically evaluated using multiple evaluation metrics, with analyses of the influence of temporal deformation irregularity and spatiotemporal prediction characteristics on model performance. The results demonstrate that the framework predicts retaining wall deformation associated with up to 5.0 m of additional excavation with an average mean absolute error of 1.4 mm and a coefficient of determination of 0.93 across the excavation sites. These results indicate that the framework, although trained exclusively on numerically simulated and augmented database, can be effectively applied to diverse field excavation conditions and achieve a reliable level of prediction accuracy in practical retaining wall deformation prediction.

Diffusion models have demonstrated strong performance in time series modeling due to their ability to progressively capture complex data distributions through iterative denoising. However, existing approaches struggle with frequency-sensitive denoising, high-frequency reconstruction and balancing global trends with local dynamics. To address these limitations, we propose \textbf{HyFAD}, a \textbf{Hy}brid time-frequency \textbf{D}iffusion model with \textbf{F}requency-\textbf{A}ware embedding for time series imputation. Built upon the DDPM paradigm, HyFAD adopts a coupled time-frequency diffusion framework, in which the reverse denoising proceeds sequentially from the time domain to the frequency domain, enabling coarse-to-fine generation. Specifically, the time-domain diffusion process captures low-frequency global trends, while the frequency-domain diffusion process refines high-frequency spectral components. We further introduce a frequency-aware step embedding that exploits the relationship between diffusion steps and spectral components, providing step-dependent spectral guidance and facilitates more accurate band-wise reconstruction. Extensive experiments on multiple benchmark datasets demonstrate that HyFAD achieves state-of-the-art performance. Our source code is available at https://github.com/hongfangao/HyFAD.

While Transformer-based architectures have established themselves as a dominant paradigm in Multivariate Time Series Forecasting (MTSF), their core self-attention mechanism inherently functions as a low-pass filter, systematically smoothing out high-frequency signals vital for sharp local changes. Recent advancements have increasingly incorporated frequency-domain operations to address this bias, however, most existing designs rely on fixed spectral bases and apply sequence-wise (uniform) modulation, implicitly assuming a time-invariant frequency response. This overlooks a key property of real-world series that their spectral characteristics often evolve over time, making uniform modulation insufficient for capturing fine-grained temporal dynamics. To tackle these limitations, we propose FAiT, a Frequency-Aware inverted Transformer. Specifically, FAiT rectifies the spectral bias internally through Inverted Attention, which interprets the attention map as a learnable low-pass operator and constructs a dedicated complementary high-pass branch by inverting the attention matrix to recover attenuated transient signals. Furthermore, FAiT introduces Dynamic Temporal-Frequency Modulation (DTFM), which synthesizes instance-conditioned weights to adaptively re-calibrate the energy of spectral sub-bands, enabling fine-grained control over evolving multi-scale patterns. Extensive experiments on widely used benchmarks demonstrate that FAiT consistently outperforms state-of-the-art Transformer-based and frequency-enhanced baselines, while maintaining computational efficiency.

Accurate pedestrian trajectory prediction is essential for safe navigation in autonomous driving and intelligent transportation systems. Despite substantial progress made by recent methods, most existing approaches are limited in fully exploiting diverse observations and often overlook the scale dependency of future motion, treating multiscale features uniformly regardless of underlying motion dynamics. This limits their robustness across diverse pedestrian behaviors. To address these challenges, we propose a Predicted-MUltiSCale-Aware Network (MUSCLE-NET) for Pedestrian Trajectory Forecasting that integrates complementary multimodal cues with scale-adaptive prediction mechanisms. The proposed framework is built upon a Multiscale Multimodal Feature Extraction (MMFE) module, which combines multiscale representation, modality-aware recalibration, and directional cross-modal fusion to construct semantically aligned representations from bounding boxes, velocities, and pose information. Building on these features, a Multiscale Enhanced Hierarchical Prediction (MEHP) module performs prediction-aware future-motion refinement via a probabilistic coarse predictor, scale-aligned fusion, and progressive refinement, adaptively selecting scale-relevant cues to mitigate spatial drift. Extensive experiments on the JAAD and PIE benchmarks demonstrate that the proposed MUSCLE-Net achieves competitive performance and consistent gains compared with state-of-the-art trajectory prediction methods.

Multi-scale modeling has emerged as an effective design principle for time-series forecasting by capturing temporal dynamics at multiple resolutions. As no principled foundation has been established in the literature, we unify existing scaling methods into a scaling operator family, revealing a fundamental limitation of existing approaches: reliance on fixed and discrete scaling. To address this limitation, we propose SiGMA (Single Generalized Multi-scale Architecture), which enables distance-aware scaling via the learnable discrete Gaussian (LDG) kernel grounded in scale-space theory. We evaluate SiGMA comprehensively on long- and short-term forecasting benchmarks against state-of-the-art multi-scale baselines. SiGMA outperforms all competitors on both tasks, especially achieving the best performance in 13 out of 16 long-term evaluation settings. Beyond accuracy, SiGMA significantly improves training speed by up to 5.3 times and reduces memory consumption by up to 3.8 times over the strongest competitors. Code is available at https://github.com/cheonwoolee/SiGMA.

Medical time series are central to healthcare, enabling continuous monitoring and supporting timely clinical decisions. Despite recent progress, existing methods struggle to jointly model local-global dynamics and handle nonstationarities like baseline drift, while often failing to capture latent channel interactions. To address these challenges, we propose MedMamba, an end-to-end architecture that integrates state space models with domain-specific inductive biases. Specifically, MedMamba first employs multi-scale convolutional embeddings to capture discriminative local morphology. Second, to mitigate nonstationarity, we introduce a tri-branch differential state space encoder that processes raw, temporal-difference, and frequency-domain views, fusing them to emphasize informative patterns while suppressing drift. Furthermore, to uncover latent channel correlations, we design a spatial graph Mamba module that learns a directed dependency structure regularized toward sparsity and acyclicity, which obviates the need for predefined graphs. Extensive experiments on five real-world datasets demonstrate that MedMamba achieves state-of-the-art performance while maintaining linear computational complexity, and ablation studies validate each component's contribution.Code is available at https://github.com/zhangda1018/MedMamba.

Deep forecasting models often suffer from attenuated periodic perception and entangled trend-noise representations as network depth increases. Moreover, the widely adopted channel-independent paradigm, while improving training stability, disrupts intrinsic dynamic coordination among variables, hindering the modeling of cross-variable consistency in multivariate time series. To address these issues, we propose PESD-TSF, a physics-inspired structured decomposition framework for long-term time series forecasting that jointly emphasizes interpretability and predictive accuracy. PESD-TSF introduces three key designs. First, a Multiplicative Periodic Gating mechanism incorporates continuous-time priors to dynamically modulate signal amplitudes, preserving periodic structures across deep layers. Second, a multi-scale structured encoder integrates detrended attention with hierarchical sampling to explicitly decouple long-term trends from high-frequency variations while retaining fine-grained temporal semantics. Third, to recover disrupted inter-variable dependencies, we propose Cross-Scale Collaborative Attention (CSCA) together with an RLC regularization scheme, which reconstructs global inter-variable topology in deep feature spaces and enforces physically consistent collaboration through orthogonality and consistency constraints. Extensive experiments on benchmark datasets from multiple domains demonstrate that PESD-TSF consistently achieves state-of-the-art performance, with particularly strong gains on multivariate forecasting tasks involving complex inter-variable coupling, highlighting its superior structural modeling capability and generalization.

Spatiotemporal forecasting is critical for real-world applications like traffic management, yet capturing reliable interactions remains challenging under noisy and non-stationary conditions. Existing methods primarily rely on historical spatial priors, often failing to account for evolving temporal correlations and suffering from systematic errors. In this work, we propose a nested forecasting framework that couples future macro-level regional trends with micro-level historical observations, enabling top-down guidance from abstract future representations for fine-grained forecasting. Specifically, we employ a spectral clustering-based approach to construct semantically coherent regions, providing both theoretical and empirical evidence that this representation effectively filters systematic noise while preserving essential trends. Building on this, we develop a progressive coarse-to-fine predictor to integrate these representative features into the inference process. This enables the model to leverage trend predictions to anticipate dynamic anomalies, such as periodic offsets, in advance. Furthermore, extensive experiments on multiple high-dimensional datasets demonstrate that our method consistently outperforms state-of-the-art baselines, validating the effectiveness of future macro-guided nested forecasting.

Internet of Things (IoT) systems continuously collect heterogeneous sensing signals from ubiquitous sensors to support intelligent applications such as human activity analysis, emotion monitoring, and environmental perception. These signals are inherently non-stationary and multi-scale, posing unique challenges for standard tokenization techniques. This paper proposes Dywave, a dynamic tokenization framework for IoT sensing signals that constructs compact input representations aligned with intrinsic temporal structures and underlying physical events. Dywave leverages wavelet-based hierarchical decomposition, identifies meaningful temporal boundaries corresponding to underlying semantic events, and adaptively compresses redundant intervals while preserving temporal coherence. Extensive evaluations on five real-world IoT sensing datasets across activity recognition, stress assessment, and nearby object detection demonstrate that Dywave outperforms state-of-the-art methods by up to 12% in accuracy, while improving computational efficiency by reducing input token lengths by up to 75% across mainstream sequence models. Moreover, Dywave exhibits improved robustness to domain shifts and varying sequence lengths.

Time series forecasting serves as an essential tool for many real-world applications, supporting tasks such as resource optimization and decision-making. Despite significant architectural advancements, most modern models still treat forecasting task as a fixed mapping from history to target horizons. This induces temporal decoupling across future time points and limits the model's ability to adapt to the evolving context as forecasting progresses. In this work, we present LeapTS, a novel framework that reformulates time series forecasting as a dynamic scheduling process over the prediction horizon. Specifically, LeapTS organizes the forecasting process into multi-level decisions using: (1) the hierarchical controller to dynamically select the optimal prediction scale and advancement length at each step, and (2) continuous-time state evolution driven by neural controlled differential equations. Within this process, the controlled update mechanism explicitly couples the irregular temporal dynamics with discrete scheduling feedback. Extensive evaluations on both real-world and synthetic datasets demonstrate that LeapTS improves overall forecasting performance by at least 7.4% while achieving a 2.6$\times$ to 5.3$\times$ inference speedup over representative Transformer-based models. Furthermore, by explicitly tracing the scheduling trajectories, we reveal how the model autonomously adapts its forecasting behavior to capture non-stationary dynamics.

Clinical time-series data are difficult to model with methods designed for regular sequences because they exhibit irregular sampling, frequent missing values, and heterogeneous observation patterns across variables. Existing approaches commonly use observation masks and time-gap information, but they do not continuously capture the decaying reliability of past observations or consistently organize multi-resolution information within a coherent temporal context during aggregation. To address these limitations, we propose Reliability-aware Temporal Aggregation with Mamba (ReTAMamba), which reconstructs clinical time series as time-variable token sequences, estimates observation reliability from missingness and elapsed time, and augments interval summaries with statistical descriptors. Chronological Weaving is used to integrate short- and long-term temporal information within a coherent temporal context, and a budgeted token router is applied to constrain sequence length while preserving informative summaries. Experiments on MIMIC-IV, eICU, and PhysioNet 2012 show that ReTAMamba consistently improves AUPRC over strong baselines, with average relative gains of 7.51%, 7.80%, and 10.15%, respectively. Cohort-level and patient-level analyses on eICU further showed that the learned mean decay for more dynamic signals, such as heart rate and blood pressure, was 24.3% larger than that for relatively static signals, such as laboratory test variables. These findings suggest that effective prediction in irregular clinical time series requires modeling not only what was measured, but also when and how it was observed, including information freshness and observation timeliness.

Many systems in physics, engineering, and biology exhibit multiscale stochastic dynamics, where low-dimensional slow variables evolve under the influence of high-dimensional fast processes. In practice, observations are often limited to a single trajectory of the slow component, while the fast dynamics remain unobserved, making statistical learning challenging. Approaches based on partial differential equations (PDE), such as Fokker-Planck formulations, aim to characterize the evolution of probability densities, typically requiring dense space-time data or grid-based solvers. In contrast, we adopt a trajectory-based perspective and develop a data-driven framework for learning effective stochastic dynamics from a single observed path. We model the dynamics by coupled multiscale stochastic differential equations (SDEs) and first obtain a principled model reduction through stochastic averaging. Unlike generic model reduction techniques such as PCA, this respects the dynamical structure of the original system and explicitly incorporates the interaction between slow and fast scales. A central challenge, however, is that the reduced model depends on the invariant distribution of the fast process, which is a solution to an intractable and often unknown PDE. We introduce a novel learning framework that parameterizes the invariant distribution using normalizing flows, enabling expressive density modeling in the latent fast-variable space. The flow is trained end-to-end by optimizing a penalized likelihood objective induced by the reduced stochastic dynamics. Furthermore, we develop a Bayesian variational inference procedure for uncertainty quantification, employing a second normalizing flow to approximate the posterior distribution over model parameters. This yields a scalable approach to capturing epistemic uncertainty in multiscale systems.

Effective sequence modeling fundamentally requires balancing the retention of unbounded history with the high-resolution detection of abrupt short-term variations common in real-world phenomena. However, existing state space models (SSMs) relying on high-order polynomial projection operators (HiPPO) face a critical trade-off where uniform measures dilute recent information to maintain timescale invariance, while exponential measures sacrifice global context to capture local dynamics. This paper proposes a Fractional Recurrent Architecture for Computational Temporal Analysis of Long sequences (FRACTAL), a novel architecture integrating fractional measure theory into recursive memory updates to address this limitation. By deriving projection operators with analytically characterized spectral properties and a tunable singularity index, the proposed method amplifies sensitivity to recent signal perturbations while preserving the spectral structure that encodes scale-invariant memory dynamics. This theoretical innovation is instantiated within a simplified diagonalized state space framework by modulating input projection initialization to enable simultaneous capture of multi-scale temporal features. FRACTAL achieves an average score of 87.11% on the Long Range Arena benchmark, including 61.85% on the ListOps task, outperforming the S5 model.

Multivariate time series forecasting remains a challenge due to the complexity of local temporal dynamics and global dependencies across multiple variables. In this paper, we propose \textbf{N}eighboring \textbf{P}atching \textbf{Mixer} (\textbf{NPMixer}), a hierarchical architecture featuring a Learnable Stationary Wavelet Transform that adaptively learns filter coefficients to decompose signals into trend and detail components in a data-dependent manner. Our framework introduces a Neighboring Mixer Block that captures local temporal dynamics through a series of hierarchical MLP layers operating on non-overlapping patches. Specifically, the mixer block utilizes MLPs to learn temporal patterns within and across these patches, expanding the receptive field to capture multi-scale dependencies. A Channel-Mixing Encoder is applied to high-frequency components to learn channel correlations while preserving the stability of the underlying global trend. Extensive experiments on seven benchmark datasets demonstrate that NPMixer consistently outperforms state-of-the-art models, achieving better performance in 20 out of 28 ($71.4\%$) evaluated experimental setups for MSE.

Scientific foundation models are expected to reuse representations under changes in dataset, acquisition protocol, and deployment domain, yet many sequence backbones treat scientific temporal structure as an unconstrained pattern to be fitted. We argue that this misses a central property of natural dynamical systems: neural and atmospheric time series are organized by interacting processes across multiple physical timescales, and failure to preserve this multiscale structure contributes to brittleness under distribution shift. We formalize this failure mode as temporal kernel mismatch, where a model fits in-distribution dynamics with an effective memory policy that is not anchored to the signal's physical timescales, leading to representation drift and degraded transfer. We propose Physics-Informed Multi-Scale Mamba (PIMSM), a state-space architecture that maps spectrum-estimated transition points between frequency regimes (knee frequencies) to scale-specific discretization parameters and anchors them to acquisition time units. On Human Connectome Project fMRI, PIMSM improves robustness and representation stability under severe temporal-context truncation, extreme low-resource transfer, and resting-state-to-task-state generalization. Without modality-specific adaptation, the same architecture also attains the lowest variable-wise MAE across all reported horizons and variables on Weather-5K held-out-station spatial out-of-distribution forecasting. These results support temporal-scale alignment as a practical inductive bias for scientific foundation models that must preserve structure, not only fit correlations, under deployment shift.

Subseasonal-to-seasonal (S2S) temperature forecasts, spanning several weeks to a few months, are critically needed in agriculture practice, energy planning, and extreme-weather induced risk management, yet their reliability varies substantially across seasons and regions. Forecast skill is often attributed primarily to lead time, but this perspective does not fully explain the spatiotemporal patterns of predictability. Here we show that S2S predictability is organized across interacting temporal components, spatial heterogeneity, and large-scale pattern coherence, and that this structure can be explicitly characterized and exploited. We develop a dual-scale learning framework that separates calendar-aligned historical climate context from lead-time matched recent weather evolution, combining them through spatially adaptive fusion to enable stable temperature forecasts across the 30 to 90-day window. The learned fusion weights reveal that the balance between these two temporal scales shifts systematically with season and geography: during winter, interannual context dominates over high latitudes and complex terrain where forecast is the most difficult, while summer predictions reflect a more balanced temporal contribution across the domain. This spatially explicit reorganization of predictability, rather than simple lead-time decay, emerges as the primary determinant of forecast skill within the subseasonal window. Topology-aware structural constraints further improve spatial coherence of predicted temperature fields, stabilizing large-scale pattern organization particularly over complex terrain. These results reframe S2S predictability as a structured, multi-scale phenomenon, providing a more interpretable foundation for improving forecast systems and informing their use in practice.

Long-term time series forecasting requires models that simultaneously capture rapid oscillations, medium-range periodicities, and slowly evolving macro-trends from a fixed look-back window. Existing lightweight MLP-based models typically operate on a single temporal resolution, limiting their ability to explicitly model patterns at multiple scales. We propose MSMixer, a channel-independent multi-scale MLP architecture that addresses this limitation through three complementary innovations: (i) three parallel scale branches at down-sample factors {1x, 4x, 16x} with independent MLP blocks, (ii) a learnable softmax gate that dynamically weighs branch outputs, and (iii) a DLinear complementary shortcut that provides full-window trend and seasonality context. MSMixer contains only 112K parameters at H=96 and runs at O(T) complexity. Evaluated on four ETT benchmarks with standard chronological splits and three random seeds, MSMixer achieves the lowest average MSE (0.357) among lightweight models, outperforming DLinear (0.386, -7.4%) and NLinear (0.365, -2.1%), winning 12 of 16 configurations. Against five Transformer-based baselines from the literature, MSMixer achieves best or second-best MSE in 9 of 16 configurations while using 5x fewer parameters than PatchTST. Ablation and sensitivity analyses confirm the complementary contributions of the multi-scale branches and the DLinear shortcut.

Time-series data are inherently multiscale, spanning diverse temporal granularities from coarse trends to fine-scale dynamics. However, existing time-series generative models provide limited control over the temporal granularity of both inputs and outputs, restricting their ability to condition on user-provided coarse sketches and generate samples at a desired target granularity. To address this, we introduce TimeTok, a unified framework for Granularity-Controllable Time-Series Generation (GC-TSG), which generates time series at any target granularity from any coarser input (e.g., rough sketches) or without conditioning. At the core of TimeTok is a hierarchical tokenization strategy that maps time series into an ordered sequence of tokens, from coarse to fine temporal granularity. Our autoregressive generation process operates across these granularity levels, producing token blocks that are decoded back into continuous time series. This design naturally enables GC-TSG within a single framework, where controlling the number of token blocks provides explicit control over output detail. Experiments show that TimeTok excels at GC-TSG tasks while achieving state-of-the-art performance in standard generation. Furthermore, we showcase TimeTok's potential as a foundational tokenizer by training on multiple datasets with heterogeneous temporal granularities, verifying strong transferability that consistently outperforms models trained on individual datasets. To our knowledge, this is the first unified framework that covers the full generative spectrum for time series, offering a valuable foundation for models that benefit from diverse temporal granularities.

In real-world applications of noninvasive electroencephalography (EEG), specialized decoders often show limited generalizability across diverse tasks under subject-independent settings. One central challenge is that task-relevant EEG signals often follow different temporal organization patterns across tasks, while many existing methods rely on task-tailored architectural designs that introduce task-specific temporal inductive biases. This mismatch makes it difficult to adapt temporal modeling across tasks without changing the model configuration. To address these challenges, we propose DSAINet, an efficient dual-scale attentive interaction network for general EEG decoding. Specifically, DSAINet constructs shared spatiotemporal token representations from raw EEG signals and models diverse temporal dynamics through parallel convolutional branches at fine and coarse scales. The resulting representations are then adaptively refined by intra-branch attention to emphasize salient scale-specific patterns and by inter-branch attention to integrate task-relevant features across scales, followed by adaptive token aggregation to yield a compact representation for prediction. Extensive experiments on five downstream EEG decoding tasks across ten public datasets show that DSAINet consistently outperforms 13 representative baselines under strict subject-independent evaluation. Notably, this performance is achieved using the same architecture hyperparameters across datasets. Moreover, DSAINet achieves a favorable accuracy-efficiency trade-off with only about 77K trainable parameters and provides interpretable neurophysiological insights. The code is publicly available at https://github.com/zy0929/DSAINet.

Time series forecasting plays a pivotal role in critical sectors such as finance, energy, transportation, and meteorology. However, Long-term Time Series Forecasting (LTSF) remains a significant challenge because real-world signals contain highly entangled temporal dynamics that are difficult to fully capture from a purely 1D perspective. To break this representation bottleneck, we propose TriTS, a novel cross-modal disentanglement framework that projects 1D time series into orthogonal time, frequency, and 2D-vision spaces.To seamlessly bridge the 1D-to-2D modality gap without the prohibitive $O(N^2)$ computational overhead of Vision Transformers (ViTs), we introduce a Period-Aware Reshaping strategy and incorporate Visual Mamba (Vim). This approach efficiently models cross-period dependencies as global visual textures while maintaining linear computational complexity. Complementing this, we design a Multi-Resolution Wavelet Mixing (MR-WM) module for the frequency modality, which explicitly decouples non-stationary signals into trend and noise components to achieve fine-grained time-frequency localization. Finally, a streaming linear branch is retained in the time domain to anchor numerical stability. By dynamically fusing these three complementary representations, TriTS effectively adapts to diverse data contexts. Extensive experiments across multiple benchmark datasets demonstrate that TriTS achieves state-of-the-art (SOTA) performance, fundamentally outperforming existing vision-based forecasters by drastically reducing both parameter count and inference latency.

Structural health monitoring plays a critical role in ensuring structural safety by analyzing vibration responses from engineering systems. This paper proposes a Spectro-Temporal Alignment framework and a Hybrid Spectro-Temporal Fusion framework that integrate arrival-time interval descriptors with spectral features to capture both fine-scale and coarse-scale vibration dynamics. Experiments conducted on data collected from an LDS V406 electrodynamic shaker demonstrate that the proposed spectro-temporal representations significantly outperform conventional input formulations. The results indicate that a temporal resolution (Δτ) of 0.008 of 0.02 favors traditional machine learning models, whereas a finer resolution (Δτ) of 0.008 effectively unlocks the performance potential of deep learning architectures. Beyond classification accuracy, a comprehensive stability analysis based on condensed indices, including mean performance, standard deviation, coefficient of variation, and balanced score, shows that the proposed hybrid framework consistently achieves higher accuracy with substantially lower variability compared to baseline and alignment-only approaches. Overall, these results demonstrate that the proposed framework provides a robust, accurate, and reliable solution for vibration-based structural health monitoring.

Medical time series, such as electrocardiograms (ECG) and electroencephalograms (EEG), exhibit complex temporal dynamics and structured cross-channel dependencies, posing fundamental challenges for automated analysis. Conventional convolutional and recurrent models struggle to capture long-range dependencies, while Transformer-based approaches incur quadratic complexity and often introduce redundant interactions that are misaligned with the intrinsic structure of physiological signals. To address these limitations, we propose MedMamba, a principle-driven multi-scale bidirectional state space architecture tailored for medical time series classification. Our design is guided by three key inductive biases of physiological signals: spatial centralization, multi-timescale temporal composition, and non-causal contextual dependency. These principles are instantiated through a lightweight channel-mixing module for cross-channel reparameterization, multi-scale convolutional tokenization for temporal decomposition, and bidirectional Mamba blocks for efficient global context modeling with linear complexity. Extensive experiments on six benchmark datasets spanning EEG, ECG, and human activity signals demonstrate that MedMamba consistently outperforms state-of-the-art methods across diverse modalities. Notably, it achieves 85.97% accuracy on PTB and establishes new state-of-the-art performance on the challenging ADFTD dataset (54.72% accuracy and 52.01% F1-score). Strong results on long-sequence benchmarks, such as SleepEDF, further validate its capability in modeling long-range dependencies. Moreover, MedMamba achieves a speedup of 4.6x in inference, highlighting its practicality for real-time clinical deployment. These results suggest that principle-guided state space modeling offers an effective and scalable alternative to Transformer-based approaches for medical time series analysis.

Autonomous Aerial Manipulators (AAMs) are inherently coupled, nonlinear systems that exhibit nonstationary and multiscale residual dynamics, particularly during manipulator reconfiguration and abrupt payload variations. Conventional analytical dynamic models rely on fixed parametric structures, while static data-driven model assume stationary dynamics and degrade under configuration changes and payload variations. Moreover, existing learning architectures do not explicitly factorize cross-variable coupling and multi-scale temporal effects, conflating instantaneous inertial dynamics with long-horizon regime evolution. We propose a predictive-adaptive framework for real-time residual modeling and compensation in AAMs. The core of this framework is the Factorized Dynamics Transformer (FDT), which treats physical variables as independent tokens. This design enables explicit cross-variable attention while structurally separating short-horizon inertial dependencies from long-horizon aerodynamic effects. To address deployment-time distribution shifts, a Latent Residual Adapter (LRA) performs rapid linear adaptation in the latent space via Recursive Least Squares, preserving the offline nonlinear representation without prohibitive computational overhead. The adapted residual forecast is directly integrated into a residual-compensated adaptive controller. Real-world experiments on an aerial manipulator subjected to unseen payloads demonstrate higher prediction fidelity, accelerated disturbance attenuation, and superior closed-loop tracking precision compared to state-of-the-art learning baselines, all while maintaining strict real-time feasibility.