Clinical Outcome Prediction

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18 papers in the last four weeks, up 157% on the four weeks before. 0.2% of all new papers.

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Latest papers 174

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TRAPS: Therapeutic Response Analysis via Pathway-informed Stratification
Jun 5, 2026Sujoy Banik, Sayantan Chakraborty, Boishakhi Das Toma +4Cancer Genomics Cancer Survival Prediction
Rajshahi University of Engineering & Technology Bangladesh · University of Dhaka Bangladesh · American International University of Bangladesh Bangladesh +2
Learning to model pediatric asthma exacerbation from multiple risk factors: a case study in coastal Virginia
Jun 4, 2026Jonathan Colen, Eric Werner, Maryam Golbazi +6Healthcare Interpretable ML
Joint Institute on Advanced Computing for Energy and Science, Old Dominion University, Suffolk, VA, 23535, U.S.A. · School of Data Science, Old Dominion University, Norfolk, VA, 23529, U.S.A. · Eastern Virginia Medical School, Macon & Joan Brock Virginia Health Sciences, Old Dominion University, Norfolk, VA, 23501, U.S.A. +5
HoT-SSM:Higher-order Temporal Knowledge Graph Reasoning with State Space Models for Health Care
Jun 4, 2026Thummaluru Siddartha Reddy, Vempalli Naga Sai Saketh, Yash Punjabi +1Clinical Outcome Prediction Hypergraph Neural Networks
Fujitsu Research of India, Bangalore
An interpretable and trustworthy AI framework for large-scale longitudinal structure-pain association studies using data from the Osteoarthritis Initiative (OAI)
Jun 3, 2026Jincheng Yu, Haoyang Li, Yiwen Liu +5Longitudinal Medical Image Analysis Clinical Outcome Prediction
Statistics & Data Science GIDP, University of Arizona · Department of Epidemiology and Biostatistics, University of Arizona · R. Kent Coit College of Pharmacy, University of Arizona +2
D2MDT: Department-aware Multidisciplinary Team Consultation with Deliberation for Efficient Clinical Prediction
Jun 2, 2026Yongqi Liang, Qidong Liu, Chunze Yang +4Clinical Outcome Prediction Multi-Agent Collaboration
Xi’an Jiaotong University, Xi’an, China
Probabilistic learning to perform pre-onset individualised prediction of disease severity: application to Veno Occlusive Disease
Jun 2, 2026Dalia Chakrabarty, Kane Warrior, Chuqiao Zhang +2Clinical Outcome Prediction Clinical Prediction
University of York, Department of Mathematics, York, YO10 5DD, U.K. · Narayana Superspecialty Hospital, Kolkata 711103, India
Multi-Modal Machine Learning for Breast Cancer Recurrence Prediction
Jun 1, 2026Jiahao Shao, Xudong Wang, Anam Nawaz Khan +3Breast Cancer Clinical Outcome Prediction
Department of Industrial & Systems Engineering, The University of Tennessee, Knoxville, TN 37996, USA · The University of Tennessee Medical Center, Knoxville, TN 37920, USA
ChatHealthAI: Aligning Electronic Health Record Representations with Large Language Models for Grounded Clinical Reasoning
Jun 1, 2026Bo-Hong Wang, Baicheng Peng, Ruilin Wang +3LLM Grounding LLM Alignment
School of Computer Science, McGill University, Montreal, QC, Canada · Mila - Quebec AI Institute, Montreal, QC, Canada
Bayesian meta-learning for modeling Alzheimer's disease progression
Jun 1, 2026Clara Hoffmann, Nadja KleinAlzheimer's Disease Meta-Learning
Scientific Computing Center, Karlsruhe Institute of Technology, Germany
Predicting the risk of colorectal anastomotic leak based on preoperative mapping of the blood supply of the bowel
Jun 1, 2026Zahra Tabatabaei, Jon Sporring, Mark Bremholm Ellebæk +1Medical Image Analysis Clinical Outcome Prediction
Computer Science Department, Københavns Universitet (KU), Copenhagen, Denmark. · Department of Clinical Research, University of Southern Denmark, Odense, Denmark. · Research Unit of Surgery, Odense University Hospital, Odense, Denmark. +1
Response-Aware Multimodal Learning for Post-Treatment Visual Acuity Forecasting
May 30, 2026Phuoc-Nguyen Bui, Van-Vi Vo, Duc-Tai Le +5Long-Term Time Series Forecasting Clinical Outcome Prediction
Research Convergence Institute, Sungkyunkwan University, Korea · Dept. of AI Systems Engineering, Sungkyunkwan University, Korea · College of Computing and Informatics, Sungkyunkwan University, Korea +2
Longitudinal Multimodal Sensing of Physical Activity and Well-Being in Older Adults
May 29, 2026Flavio Di Martino, Mattia G. Campana, Marcello Magno +2Clinical Outcome Prediction Wearable Sensing
IIT-CNR, Pisa, Italy · IFC-CNR, Pisa, Italy
Automated Prediction of Postoperative Pancreatic Fistula Using Preoperative Computed Tomography
May 29, 2026Ashok Choudhary, Chris Varghese, Leo Y. Li-Han +53D Medical Imaging Clinical Outcome Prediction
Department of Surgery, Mayo Clinic, Rochester, MN, USA · Department of Surgery, University of Auckland, Auckland, NZ · Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA +1
QDSP: An Interpretable Structured Learning Framework for Predicting Death or Cerebral Palsy in Very Low Birth Weight Infants
May 29, 2026Ling Wang, Xiaolong Li, Hui Zhou +4Interpretable ML Clinical Outcome Prediction
College of Computer Science Sichuan Normal University Chengdu, Sichuan, China · West China Second University Hospital Sichuan University Chengdu, Sichuan, China
GlucoFM: A Dual-Stream Foundation Model for Continuous Glucose Monitoring
May 29, 2026Zechen Li, Keerthana Natarajan, Weizhi Zhang +11Irregular Time-Series Modeling Latent Dynamics Modeling
Google Research · Work done during an internship at Google · University of New South Wales, Sydney
Treatment-Conditioned Diffusion for Forecasting Neurodegenerative Disease Progression
May 28, 2026Danylo Boiko, Viktoriia MishkurovaLongitudinal Medical Image Analysis Clinical Outcome Prediction
Innoloft Inc. 701 Brazos Street, Austin, TX 78701, USA · Bogomolets National Medical University Beresteiskyi Avenue, 34, Kyiv, 03057, Ukraine
Parallel Adaptive Multi-Objective Evolutionary Learning of Discretized Bayesian Network Classifiers for Clinical Data
May 27, 2026Damy M. F. Ha, Thalea Schlender, Yvette M. van der Linden +2Bayesian Networks Multi-Objective Evolutionary Optimization
Leiden University Medical Center · Centrum Wiskunde & Informatica
A Two-Scan Deep Learning Model for Predicting Dementia in Mild Cognitive Impairment
May 27, 2026Sara Fin, Alireza Moayedikia, David J. White +2Hybrid CNN-Transformer Architectures Longitudinal Medical Image Analysis
Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC, Australia · School of Business Law and Entrepreneurship, Swinburne University of Technology, Melbourne, VIC, Australia · department of Business Technology and Entrepreneurship of Swinburne University of Technology, John Street, Hawthorn 3122, VIC, Australia +2
GraD-IBD: Graph Representation Learning from Diagnosis Trajectories for Early Detection of Inflammatory Bowel Disease
May 27, 2026Leo Y. Li-Han, Ellen L. Larson, Elizabeth B. Habermann +2Temporal GNNs Graph Representation Learning
Department of Surgery, Mayo Clinic, Rochester, MN, USA · Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA · Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN, USA +1
Prospective evaluation of multimodal respiratory failure prediction: Do chest X-rays improve performance beyond EHR signals?
May 25, 2026Xiaolei Lu, Shamim NematiClinical Outcome Prediction Multimodal Fusion
Quantitative Evaluation of the Severity of Posttraumatic Stress Disorder through Transfer Learning from Specific Phobia Data
May 25, 2026Nicolas Ricka, Gauthier Pellegrin, Denis A. Fompeyrine +3Clinical Outcome Prediction
MyndBlue, F-75008 Paris, France · DCS Corporation, Alexandria, Virginia, United States of America · Human in Complex Systems Division, DEVCOM Army Research Laboratory, Aberdeen Proving Ground, Maryland, United States of America
Multimodality Stacking with Blockwise missing values and application to the PIONeeR biomarkers study for prediction of resistance to immunotherapy
May 24, 2026Mohamed Boussena, Florence Monville, Jacques Fieschi-Meric +8Missing-Modality Learning Cancer Survival Prediction
Inria – Inserm team COMPO, COMPutational pharmacology and clinical Oncology, Centre Inria Sophia Antipolis - M´editerran´ee, Centre de Recherches en Canc´erologie de Marseille, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Pharmacy faculty, Aix-Marseille University · Veracyte SAS, Marseille, France · Assistance Publique-Hˆopitaux de Marseille (APHM), Marseille, France +4
Explainable Retinal Imaging for Prediction of Multi-Organ Dysfunction in Type 2 Diabetes
May 24, 2026Mini Han Wang, Liting Huang, Wei Hong +1Type 1 Diabetes Clinical Outcome Prediction
Faculty of Computer Science and Artificial Intelligence, Shenzhen University of Advanced Technology, Shenzhen, P.R.China · Frontier Science Computing Center, Zhuhai Institute of Advanced Technology Chinese Academy of Sciences, Zhuhai, P.R.China · Chinese University of Hong Kong, Hong Kong China +2
Distributionally Robust Transfer Learning with Structurally Missing Covariates, with Application to Cross-National Cardiac Arrest Prediction
May 22, 2026Siqi Li, Chuan Hong, Ziye Tian +9Healthcare Clinical Outcome Prediction
Centre for Biomedical Data Science, Duke-NUS Medical School, Singapore · 2Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore · Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA +13
Towards a General Intelligence and Interface for Wearable Health Data
May 21, 2026Girish Narayanswamy, Maxwell A. Xu, A. Ali Heydari +37Self-Supervised Pre-Training Clinical Outcome Prediction
1Google Research · University of Washington · University of Illinois Urbana-Champaign +2
EmoTrack: Clinical-Semantic Modeling for Text-Based Depression Severity Estimation
May 21, 2026Zhaomin Wu, Jiayi Li, Bingsheng HeMental Health Counseling Depression Detection
Department of Computer Science National University of Singapore
ChronoMedicalWorld: A Medical World Model for Learning Patient Trajectories from Longitudinal Care Data
May 21, 2026Jiangyuan Wang, Xuyong Chen, Junwei He +3Latent Dynamics Modeling Healthcare
Beijing KidneyTec Medical Technology Co., Ltd., Beijing, China
Quantitative coronary calcification analysis for prediction of myocardial ischemia using non-contrast CT calcium scoring
May 20, 2026Juhwan Lee, Sadeer Al-Kindi, Ammar Hoori +6Clinical Outcome Prediction Radiomics
Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, 23284, USA · Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 44106, USA · DeBakey Heart and Vascular Institute, Houston Methodist Hospital, Houston, TX, 77030 +2
TimeSRL: Generalizable Time-Series Behavioral Modeling via Semantic RL-Tuned LLMs -- A Case Study in Mental Health
May 20, 2026Yuang Fan, Lilin Xu, Millie Wu +8Mental Health Domain Generalization
Columbia University, USA · University of North Carolina at Chapel Hill, USA · Yale University, USA +3
Learning to Select Source-Traceable Evidence for Language-Model Prediction from Irregular Clinical Time Series
May 19, 2026Kwanhyung Lee, Juhwan Choi, Jongheon Kim +5Irregular Time-Series Modeling Healthcare
Kim Jaechul Graduate School of AI, KAIST · AITRICS

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TRAPS: Therapeutic Response Analysis via Pathway-informed Stratification

Sujoy Banik, Sayantan Chakraborty, Boishakhi Das Toma, Zainab Ghafoor+3

Rajshahi University of Engineering & Technology Bangladesh · University of Dhaka Bangladesh · American International University of Bangladesh Bangladesh+2

Cancer Genomics Cancer Survival Prediction Clinical Outcome Prediction Oncology

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Cancer treatment planning requires decisions across multiple clinical dimensions at once. Clinicians must determine whether a patient should receive targeted molecular therapy, radiation therapy, and whether they are likely to survive beyond six months. Existing pathway-informed deep learning models have been developed and tested in isolation, making fair comparison across architectures impossible. We present the first unified benchmark for pathway-guided therapy response modeling, evaluating three biologically informed architectures, BINN, GraphPath, and PATH, across five cancer cohorts drawn from The Cancer Genome Atlas, representing 2,622 patients encoded using Reactome pathway activity scores. Each model is trained jointly on all three clinical outcomes under identical data and evaluation conditions, the first study to treat pathway-structured deep learning as a combined therapy and survival prediction problem. Our results show that no single architecture wins across all tasks: PATH performs best for targeted molecular therapy prediction overall, BINN is most reliable for survival prediction, and no model produces useful predictions for radiation therapy, as the key drivers of that decision are clinical variables not captured in gene expression data. Most strikingly, GraphPath achieves an AUROC of 0.92 on prostate targeted molecular therapy prediction, the highest score in the entire benchmark, demonstrating that lateral co-regulation structure produces exceptional discriminative power when matched to a cohort with a narrow targetable driver programme, even under conditions of extreme class imbalance at only 11% positive prevalence.

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