Generative Models

Diffusion-based generative models enable powerful image editing capabilities, but achieving precise control while maintaining fidelity and safety remains challenging. We present a comprehensive theoretical and empirical study of controllable diffusion-based image editing, analyzing the trade-offs between adherence to user intent, preservation of non-target content, and output quality. Our work spans text- and mask-guided edits, point/drag manipulation, and inversion-based pipelines. We derive mathematical formulations of editing objectives and analyze dynamics of noise injection, score guidance, and inversion error. We provide theoretical bounds on reconstruction error, stability under repeated edits, and locality of changes. We propose algorithmic frameworks (with pseudocode) for mask-localized and instruction-guided editing, and present extensive experiments comparing state-of-the-art methods (e.g.\ TF-ICON \cite{lu2023tficone}, DragFlow \cite{zhou2025dragflow}, InstructPix2Pix \cite{brooks2023instructpix2pix}, UltraEdit \cite{zhao2024ultraedit}) on multiple tasks and metrics (FID, identity similarity, CLIP alignment, artifact scores, etc). Our results reveal key failure modes, such as identity drift, prompt sensitivity, and compositional errors. We also discuss ethical considerations in image editing, including misuse risks, bias, consent, and concept erasure techniques (e.g.\ MACE \cite{lu2024mace}, ANT \cite{li2025ant}, EraseAnything \cite{gao2024eraseanything}) as safeguards. We conclude with best practices and future directions for responsible, high-fidelity diffusion-based editing.

The success of generative molecular design hinges on a model's steerability toward high-reward samples. Because many molecular properties are intrinsically linked to molecular size, accurately capturing the joint distribution of properties and the number of atoms is essential. However, current diffusion and flow-based models fix the number of atoms, which ultimately limits their ability to navigate this complex relationship. To address this, we introduce Morph, a flexible-size generative model for conditional and unconditional 3D molecular design based on geometric graphs. By dynamically adapting size, Morph can seamlessly integrate existing structural priors, like scaffolds, and significantly enhances property steering. We show that Morph matches current fixed-size state-of-the-art models while offering the benefit of unparalleled sampling flexibility. We demonstrate out-of-distribution generation in regimes where previous models fail, paving the way for enhanced generative modeling for molecular design.

As AI systems become more widely adopted, the demand for factual and faithful generation grows. Properly attributing information through citations becomes, therefore, crucial. This work introduces FullCite, a framework that, in contrast to most previous works, generates structured inline citations linking each claim to both its source document and supporting evidence. FullCite proposes three strategies to inline citation generation: prompt-based generation, constrained decoding over a citation grammar, and posthoc span alignment. Using three question answering benchmarks, namely, ASQA, BioASQ, and ExpertQA, we assess citation quality and faithfulness along three dimensions: document-level correctness, evidence span identification, and claim-citation faithfulness. Our evaluation shows that while LLMs are generally effective at identifying relevant documents, they struggle to identify the precise supporting spans within them. This gap suggests that achieving faithful attributed QA will require research to place greater emphasis on precise evidence span identification.

We argue that modern generative models create structural risks for knowledge and cultural production at current, sub-AGI capability levels. We define Human Temporal Learning (HTL) as path-dependent knowledge accumulation through sustained engagement with problems over time. Generative outputs increasingly resemble HTL-intensive work in surface features, so verifying whether a given output reflects genuine human learning grows costly relative to its expected benefit. Once verification loses economic justification, evaluators reward outputs regardless of production mode, and producers who invested years of learning compete on price against outputs that cost almost nothing to generate. We call this pathway value collapse and formalize it through a costly-inspection framework. Cross-domain evidence from academic publishing, legal practice, content platforms, and software security maps onto four stages of verification erosion. Alignment success is orthogonal. Better-aligned models narrow observable gaps between human and AI outputs, making source verification harder and intensifying competitive pressure against HTL-intensive work even when individual AI outputs improve.

Standard continuous-time generative models rely on monolithic architectures that must navigate vastly different signal regimes, from isotropic noise to intricate data distributions. While scaling model capacity improves performance, deploying a massive network uniformly across the entire generative timeline is inherently inefficient. In this work, we propose Complexity-Balanced Splitting (CBS), a principled framework for temporal capacity allocation that distributes the generative workload across multiple specialized sub-networks. Grounded in function approximation theory and de Boor's equidistribution principle, CBS partitions the diffusion timeline into segments of equal approximation burden, allocating more representational capacity to regions where the generative dynamics are more difficult to model. To estimate this local complexity, we introduce two complementary and tractable monitor functions: a spatial measure based on the flow's Dirichlet energy, and a geometric measure based on the acceleration of the sampling trajectories. Using a lightweight auxiliary model to estimate these complexity profiles, our approach eliminates the need for heuristic temporal splits or computationally expensive search procedures. Extensive evaluation across multiple architectures (SiT, JiT, and UNet) and datasets demonstrates that CBS consistently improves synthesis quality without increasing per-step inference cost. In particular, CBS improves FID by ~35% on SiT-XL with CFG relative to naive temporal partitioning. Project page is available at https://noamissachar.github.io/CBS/.

Multimodal generative models produce fluent outputs but remain unreliable when generation must respect structured, domain-specific, or safety-critical knowledge. Existing methods incorporate knowledge through mechanisms such as prompt augmentation, guidance, latent editing, or fine-tuning, yet they are typically categorized by technique rather than by the component of the generative process they modify. We argue that knowledge infusion in iterative generative models is fundamentally anintervention-layer problem. Since thegenerative process unfolds as a trajectory of internal states, knowledge can act on four structurally distinct components of this process: the input/output boundary, the transition function, the intermediate state, and the model parameters. This maps to four intervention layers: surface, trajectory, latent, and parametric infusion. We instantiate the framework in diffusion models, map representative methods to all four layers, and derive design principles for multi-layer composition. In a controlled safety-alignment experiment using a multimodal knowledge graph with two diffusion backbones, we implement three of the four layers cumulatively, surface (input-side and output-side) and trajectory--latent (mid-generation). We show empirically that each additional layer addresses failure classes that prior layers cannot reach, reducing knowledge-violating outputs by 70.97% compared to vanilla generation and empirically confirming the framework's complementarity prediction.

This paper presents a distributed conversational framework for human-robot collaborative manipulation that integrates local language and vision-language models (VLMs) with a Robot Operating System 2 (ROS 2)-based execution stack. Language understanding, visual grounding, orchestration, and motion execution run as separate ROS 2 nodes, enabling flexible deployment across distributed hardware while maintaining a responsive control loop. From free-form user commands, the system generates structured action requests for pick, place, and handover. It uses a VLM to return image-space targets, which are converted into metric robot-frame goals using depth and calibration. A web dashboard exposes intermediate intent and grounding overlays (pixel, depth, and robot-frame) and requires explicit operator confirmation before any motion is executed. Experiments on a Franka FR3 platform evaluate end-to-end task reliability and latency under increasing working table scene ambiguity and compare alternative LLM/VLM configurations in the same pipeline. Code and full documentation are available at github.com/cogrob-tuni/franka-llm.

Neurodegenerative disorders such as Alzheimer's disease exhibit highly organized patterns of regional brain vulnerability, yet the biological mechanisms underlying this spatial selectivity remain incompletely understood. Existing imaging-transcriptomic studies have largely relied on correlation-based analyses between gene expression and neuroimaging phenotypes, limiting their ability to model how molecular organization gives rise to neurodegeneration. Here, we introduce a cross-scale spatially-aware generative framework for modeling transcriptomic programs underlying cortical neurodegeneration. Regional transcriptomic profiles were derived from the Allen Human Brain Atlas using 910 landmark genes across 68 cortical regions. Neurodegenerative vulnerability maps were constructed from ADNI FreeSurfer cortical thickness measurements by computing regional cortical thinning differences between cognitively normal controls (NC = 926) and Alzheimer's disease subjects (AD = 426). A variational generative architecture was used to learn latent biological programs linking regional gene-expression organization to cortical degeneration while incorporating graph-based spatial smoothness regularization to preserve cortical organization. The proposed framework achieved strong prediction of regional neurodegenerative vulnerability, yielding an explained variance of 0.8604 and a significant spatial correlation between predicted and observed cortical degeneration profiles (r = 0.9439, p < 0.001). The learned latent representations revealed structured transcriptomic organization associated with distributed disease susceptibility. These findings demonstrate that biologically constrained generative modeling can bridge microscale molecular organization with macroscale neurodegeneration, providing a foundation for spatially-aware generative neurobiology and computational neuroscience.

Query recommendation in e-commerce search aims to proactively suggest queries that match users' potential interests. However, existing methods mainly optimize query-level relevance, while neglecting whether the retrieved products align with users' downstream preferences. This mismatch often leads to high query click through rates (CTR) but low product conversion rates (CVR). To bridge this gap, we propose QueryAgent-R1, a memory-augmented agentic framework that improves end-to-end alignment via chain-of-retrieval optimization. Our QueryAgent-R1 grounds query generation in real inventory retrieval, allowing the agent to validate and refine queries based on retrieved products. We also design a consistency reward in the agentic reinforcement learning (RL) process to jointly optimize query relevance and downstream engagement. In addition, we construct a memory abstraction module for efficient user profiling. To support offline evaluation, we construct two datasets based on both proprietary industrial data and public datasets, on which QueryAgent-R1 consistently outperforms strong baselines. Moreover, on a large scale production platform, QueryAgent-R1 improves Query CTR by 2.9% and guided CVR by 3.1% in online A/B tests.

Unsupervised conditional image generation (UCGen) aims to control generation without relying on manually annotated labels, yet remains challenging due to unstructured semantic representations across granularities. To address this, we propose a novel coarse-to-fine UCGen framework (CoFi-UCGen) that explicitly disentangles global semantics from fine-grained variations, which to the best of our knowledge, sets out the first successful attempt for both coarse- and fine-grained conditional generation without any labels. More specifically, we first propose the adversarial semantic reciprocal learning theory to ensure the semantic consistency and completeness between images and latent spaces. Based on the consistency, we propose the bit-codes to learn a structured coarse-grained latent space, and further prove distinct global semantics inherent from our bit-codes while preserving independent noise sampling for generation. Building upon these bit-codes, we establish a fine-grained semantic basis and introduce a hierarchical modulation mechanism in diffusion models, by enabling layer-wise injection from coarse conditions to progressively control fine-grained attributes during generation. Extensive experiments demonstrate that without any label priors or pre-trained feature extractors, our CoFi-UCGen consistently outperforms existing UCGen methods in terms of image quality, semantic consistency, and control accuracy, verifying the effectiveness of explicit coarse-to-fine semantic decomposition for the challenging UCGen task.

Generative models have shown promising results for speech enhancement (SE), but they often rely on multi-step inference, limiting low-latency deployment. We propose SB-RF, a one-step generative framework that integrates Rectified Flow (RF) with Schrödinger Bridge (SB) theory. During training, SB-RF samples intermediate states from an SB time marginal and trains a conditional velocity field with the RF velocity-matching objective. At inference, SB-RF starts from the noisy observation and applies a single Euler update. Experiments show that SB-RF achieves competitive performance among generative methods on the VoiceBank-DEMAND benchmark. To further assess performance beyond this standard setting, we evaluate SB-RF on a simulated low signal-to-noise ratio test set using an expanded training dataset. Under these conditions, SB-RF achieves superior performance over the compared baselines, supporting its potential for real-world applications.

Generative artificial intelligence (AI) is increasingly used to support self-directed learning, yet student interaction with such systems often remains unstructured, limiting engagement in deeper cognitive processes. This study examines how instructional guidance shapes student and AI interaction in construction education. A five-step prompting framework grounded in Generative Learning Theory (GLT) is introduced to guide learner interaction during review activities. A controlled experiment compares three learning conditions: slide-based learning, unprompted AI-supported learning, and prompted AI-supported learning. Learning performance is assessed using multiple-choice and open-ended tasks, and user experience is measured using the User Experience Questionnaire (UEQ). Performance differences are concentrated on tasks requiring explanation and reasoning. The prompted condition achieves higher open-ended scores, with an improvement of approximately 2 or 3 points on a scale of 18 (p < 0.01), while no significant differences are observed in multiple-choice performance. The unprompted condition remains comparable to slide-based learning. These findings indicate that the effectiveness of AI-supported learning depends on how interaction is structured. The proposed framework provides a basis for integrating learning science principles into generative AI systems for construction education.

Recent progress in generative modeling has made safety control a central challenge, yet existing approaches remain largely model-specific, requiring retraining or tailored interventions for each new architecture. In this work, we ask whether safety can be represented as a portable latent direction, learned once and reused across heterogeneous generators. We introduce the first framework for cross-model safety steering, in which a safety direction is estimated in a source LLM from paired safe-unsafe prompts, transported to a target generator through a lightweight alignment fitted on benign data alone, and applied at inference time. Crucially, our pipeline never accesses unsafe data on the target side, isolating whether safety can be transferred through shared representation geometry. Beyond a single global direction, we also identify a multi-vector extension that captures category-specific safety behaviors, enabling more selective control. We evaluate our approach in text-to-image and text-to-video generation across diverse source-target model pairs. Across models, transferred safety directions achieve ASR reduction and CLIP-Score/FID trade-offs comparable to directions learned natively on the target model using unsafe data, while requiring no target-side unsafe data. This indicates that safety improvements do not come at the expense of generation quality. Our results point to a modular view of safety: safety-relevant behavior is not purely model-local, but can be controlled through latent directions that persist across models. This suggests a new path toward lightweight, reusable safety mechanisms that do not require target-side unsafe data.

The title of a research paper conveys its primary idea and, occasionally, its conclusions in a clear and concise manner. Choosing an appropriate title is often challenging, and automated title generation can assist authors in this task. In this work, we propose a technique to generate paper titles from abstracts using open-weight pre-trained and large language models. We use the CSPubSum and LREC-COLING-2024 datasets and introduce a new dataset, SpringerSSAT, curated from four Springer journals in the social sciences. Additionally, we use GPT-3.5-turbo in a zero-shot setting to generate titles. Model performance is evaluated with ROUGE, METEOR, MoverScore, BERTScore, and SciBERTScore metrics. Our experiments show that fine-tuned PEGASUS-large outperforms other models, including fine-tuned LLaMA-3-8B and zero-shot GPT-3.5-turbo, across most metrics. We further demonstrate that ChatGPT can generate creative paper titles. Overall, AI-generated titles are generally appropriate and reliable.

Video generation models have made impressive strides in synthesizing visually compelling content, yet their outputs remain confined to the virtual domain. A natural question follows: how well do these models reflect the physical world when their generated videos leave the screen and enter reality? We propose robotic manipulation as a concrete, measurable window onto this question: if a model has truly internalized physical laws, the motion it depicts should translate into executable robot behavior. We introduce Dream$.$exe, an evaluation framework that operationalizes this criterion through a video-to-execution pipeline. Given a scene image and a task description, Dream$.$exe synthesizes a manipulation video, converts the generated motion into robot trajectories, and executes them in a physics simulator, yielding a grounding signal that purely visual metrics cannot offer. Using this pipeline, we evaluate 8 models spanning frontier closed-source generators, open-source generators, and robot-specific models. Our benchmark covers 101 manually curated manipulation tasks at three levels of physical complexity, measured across visual quality, trajectory fidelity, and execution success. Encouragingly, several models achieve measurable execution success, suggesting that generative priors learned from internet-scale data already encode meaningful physical knowledge. Yet visual quality proves a poor predictor of executability, exposing a dimension of model capability that standard visual evaluations do not capture. Dream$.$exe will be open-sourced at https://github.com/showlab/Dream.exe.

Generative models -- diffusion and flow matching -- are increasingly used to solve partial differential equation (PDE) inverse problems, enforcing the governing physics as a \emph{hard constraint} (via projection or guidance) and reporting the resulting samples as a Bayesian posterior with calibrated uncertainty. We show that this widely adopted recipe samples the wrong distribution. Conditioning a generative prior on a hard PDE constraint is conditioning on a measure-zero manifold -- an operation that is intrinsically ambiguous (the Borel--Kolmogorov paradox) and whose physically correct resolution, the small-residual-noise limit, carries a co-area (Fixman) Jacobian factor $[det(JJ^{\top})]^{-1/2}$ that projection- and guidance-based methods silently omit. We make the bias precise, show that it grows with the heterogeneity of the constraint sensitivity, and validate it on controlled problems against an \emph{i.i.d.} ground-truth arbiter. The omitted factor is not a second-order detail: removing it inflates the posterior error to $20\times$ the sampling-noise floor; minimal-displacement projection (as in PCFM) is biased at $9\times$ the floor; and a naive scalar reweighting does not fix it. We introduce \textbf{CoCoS}, a measure-aware constrained sampler that targets the correct co-area posterior, and show that it matches the gold-standard posterior to within sampling noise. Our results imply that satisfying the physics'' is not the same as sampling the posterior,'' and give a principled correction for uncertainty-aware scientific inference.

Autoregressive mesh generation has gained attention by tokenizing meshes into sequences and training models in a language-modeling fashion. However, existing approaches suffer from two fundamental limitations: (i) low tokenization efficiency, which yields long token sequences and prevents scaling to high-poly meshes, and (ii) absence of geometry-aware guidance, as generation is conditioned only on global shape embeddings rather than local surface cues. We introduce MeshWeaver, an autoregressive framework that treats mesh generation as a surface weaving process by directly predicting the next vertex instead of independent coordinates. At its core is a multi-level sparse-voxel encoder that injects geometric context into the generative process in three complementary ways: providing voxel features as vertex representations, guiding token prediction via cross-attention to voxel features, and serving as a structural scaffold that constrains generation around the input surface. Our hierarchical design enables coarse-to-fine vertex prediction in a single decoding step, while tightly coupling the generative model with 3D geometry. Extensive experiments demonstrate that MeshWeaver achieves a state-of-the-art compression ratio of 18%, can generate meshes with up to 16K faces, and significantly improves geometric fidelity over prior approaches.

Language models acting as agents over knowledge graphs generate Cypher queries that fail structurally (crashing at the database) or semantically (executing but returning wrong results). We place a pre-execution gate between query generation and a production Neo4j database. The gate validates structure through a four-backend chain culminating in execution against a mirror graph at 5.6 ms median latency. Structurally broken queries are routed to a corrector that iterates structured error feedback through a language model. On seven CypherBench schemas (2348 questions, ACL 2025) the pipeline maintains generation accuracy on every model tested, confirming it operates as a safe defensive layer. The corrector achieves 81% to 95% success across five models (mean 89%). On a template-generated corpus across nine schemas the gate catches 100% of parse errors, 100% of constraint violations, and 100% of schema-reference errors in path queries with labelled endpoints, at zero false positives across 1135 queries. Property sibling-swaps where the substituted name is valid on the target label score 0%, marking the formal boundary where structural validation ends and semantic validation must begin. A planner-based cost gate flags catastrophic plan structures before execution.

Large Language Models (LLMs) have become increasingly adopted in daily applications, with deep research standing out as a particularly important capability. Unlike traditional question-answering (QA) tasks, deep research report generation lacks definitive ground-truth, making reward design inherently unverifiable and limiting effective reinforcement learning. Existing approaches mitigate this challenge with LLM-as-a-judge and query-dependent evaluation rubrics, but they still rely on static evaluators that cannot adapt their standards as the solver improves, leading to insufficient and eventually saturated optimization pressure. We address this limitation with a \textbf{s}elf-evolving \textbf{co}-evolutionary training framework for deep \textbf{re}search evaluation and generation (SCORE), which tightly couples an evaluator and a solver in a shared-parameter learning process. Rather than treating generation and evaluation as isolated modules, we leverage their intrinsic connection to enable joint improvement within a single shared-parameter model. To restrict this process, we introduce a meta-harness, which dynamically controls the evaluation environment based on solver performance, encouraging valid evaluation dimensions and sufficiently deep evaluator search. Extensive experiments on deep research benchmarks demonstrate consistent improvement in report generation quality, showing that co-evolving evaluation and generation is a promising direction for training open-ended research agents.

Generating realistic and diverse graphs is a key problem in machine learning, with applications in molecular discovery, circuit design, cybersecurity, and beyond. However, current graph generative models remain limited by scalability and novelty. Diffusion-based methods often require costly full-adjacency operations and long denoising chains, while many autoregressive and hybrid models have at least quadratic complexity. In addition, these models often imitate training graphs rather than generalize beyond them. We propose a lightweight autoregressive framework to address these issues. It uses a structure-guided topological ordering to serialize graphs into regular edge sequences, enabling near log-linear generation, and a two-phase training strategy that combines exploration-oriented augmentation with iterative refinement to reduce overfitting and promote controlled novelty. Experiments on molecular and non-molecular benchmarks show that our approach improves novelty while preserving high validity and uniqueness. The framework also supports both LSTM and Mamba-style causal sequence backbones, with large-memory accelerators enabling longer graph-sequence experiments beyond typical GPU limits.

Large language models often express high confidence in answers that are wrong. Standard calibration remedies typically act globally or at the score level, reducing unwarranted confidence but also risking erosion of warranted confidence on correct answers. We introduce Probe-Conditioned Head Intervention (PCHI), an inference-time method that uses a frozen probe to detect likely wrong-but-confident responses and conditionally rescales downstream attention-head outputs during confidence generation. On Qwen3-4B-Instruct solving OpenMathInstruct problems with a structured binary confidence field, readout-token PCHI converts 82.2% of originally wrong-yes confidence readouts to $\texttt{no}$, while a joint intervention across upstream confidence-template tokens reduces ECE from 21.9% to 9.2% and damages only 5.1% of originally correct-yes readouts. The readout-token effect also appears on Gemma3-4B, though upstream interventions are weaker and more mask-dependent. These results show that verbalized overconfidence can be selectively reduced through conditionally applied internal intervention, partially decoupling the suppression of unwarranted confidence from the loss of warranted confidence.

Modeling temporal evolution is important to analyzing and reasoning about scientific phenomena, yet most machine learning methods provide deterministic forward predictions that overlook multiple plausible outcomes and rarely support backward reasoning, limiting their usefulness in practical scientific workflows. We present a framework that integrates diffusion-based generative modeling with interactive visual analytics for scientific exploration. We introduce DiffUNet^2, a conditional diffusion model that enables bidirectional, any-to-any generation across time and captures distributions of plausible system evolutions. Built upon the model, our interactive system supports branching timeline exploration, user-guided state editing, and probability-space navigation, enabling scientists to actively explore alternative hypotheses rather than passively observe predictions. We evaluate the model on 5 datasets across different scientific domains to validate its predictive accuracy and probability-space ensemble quality. In collaboration with domain experts, we demonstrate the effectiveness of our approach in supporting practical scientific temporal data analysis workflows. By integrating modeling and visual interaction, our approach enables scientists to interactively explore system dynamics, transforming generative models into tools for hypothesis-driven scientific analysis.

We propose PatchScene, a novel diffusion-based framework for large-scale LiDAR scene completion. Unlike existing methods that rely on global latent representations or dense voxel grids, PatchScene adopts a patch-based voxel diffusion paradigm that explicitly generates fine-grained geometry within localized 3D regions. To ensure coherent reconstruction at both spatial and temporal scales, we introduce a confidence-guided spatio-temporal fusion mechanism that integrates overlapping patches and adjacent frames in a unified generative process. Furthermore, we design an Annular-Flow diffusion strategy that leverages the radial density pattern of LiDAR scans to progressively propagate high-fidelity information from near-range to far-range regions, enabling spatially unbounded scene completion. Extensive experiments on the SemanticKITTI benchmark demonstrate that PatchScene achieves state-of-the-art performance across all standard metrics, surpassing previous approaches in both geometric accuracy and temporal consistency. Remarkably, the model trained on 20 m LiDAR ranges generalizes effectively to 50 m scenes without retraining, highlighting its strong scalability and generalization capability for real-world autonomous driving applications.

Modern generative models possess a deep understanding of visual content, yet training them for image editing typically requires massive datasets of paired examples. This limits scalability, especially for video editing where collecting paired data is prohibitively expensive. We propose Bootstrap Your Generator (ByG), a general framework for unpaired training of flow matching editing models. It leverages the base model's knowledge without any external signal. Our approach pairs instruction-following cues extracted from the frozen model with cycle-consistency for structure preservation. To make this tractable, we propose to route gradients from downstream losses over clean predictions to noisy training states. We demonstrate state-of-the-art results on challenging data-scarce image and video editing scenarios. Extensive evaluations and user studies show that our method effectively generalizes to unseen domains and outperforms supervised baselines trained on millions of samples. Analysis reveals that our gradient routing bridges the train-inference gap, and extracting semantic cues from a base model provides a robust training signal that obviates the need for external reward models.

Recent world action models leverage video foundation models by aligning broad visual-dynamics priors with executable robot actions. We revisit this alignment from a distributional perspective. Existing formulations typically narrow the aligned prior into an observation-conditioned policy distribution over future actions. In contrast, we keep the distribution broader by modeling the joint space of interaction videos and executable hand trajectories under multiple conditioning regimes. We propose Donk, a unified video-action denoising model for dexterous hands. With language, an initial image, and the initial hand state, Donk samples future videos and bimanual MANO trajectories as an action policy. Without the image condition, the same denoising architecture samples paired video-action rollouts from a text-conditioned distribution, turning the aligned video prior into a data engine. Across action, video, and text-only generation evaluations, Donk improves dexterous trajectory accuracy, preserves strong video fidelity, and produces smooth text-conditioned action rollouts under the same unified training recipe.

Few-step distillation has emerged as a critical component in the development of advanced visual generative foundation models, substantially reducing inference overhead while enabling real-time generation and cost-efficient deployment across a broad range of practical scenarios. However, prior work has predominantly focused on advancing training objectives, while comparatively overlooking the training recipe, which has become increasingly critical in the era of large-scale foundation models. In this work, we systematically revisit the training recipe under the well-established distribution matching distillation (DMD) framework for both text-to-image generation and image editing, focusing on three key dimensions: training data composition, teacher guidance within DMD, and task mixture. Our empirical analysis reveals several non-obvious and counterintuitive phenomena, ultimately motivating the development of Qwen-Image-Flash. These findings highlight that effective few-step distillation depends not only on carefully designed objectives, but also on a principled training recipe.

Latent diffusion models leverage visual tokenizers to compress images into latent spaces for efficient generative modeling. However, better reconstruction quality of a tokenizer does not necessarily translate into better generation quality, suggesting that latent representations should be evaluated not only by fidelity but also by their diffusability. Recent studies have proposed diverse explanations for diffusion-friendly latent spaces, including semantic separability, affine equivariance, distribution uniformity, spatial structure, spectral smoothness, and manifold continuity. Yet these properties are often validated on a limited set of tokenizers, leaving it unclear which factors are most predictive of downstream generation quality and whether such conclusions hold beyond the specific settings in which they are introduced. In this work, we conduct a systematic study of latent diffusability by training a large collection of tokenizers with diverse regularization strategies, architectures, and latent configurations, and evaluating them with multiple downstream diffusion backbones. Our analysis identifies several latent properties that consistently correlate with generation quality and exhibit strong generalization across experimental settings. Beyond existing metrics, we introduce Velocity Irreducible Variance (VIV), a measure of velocity ambiguity induced by trajectory crossings. Extensive experiments show that VIV is one of the most stable predictors of generation quality.

Recent generative models can now produce visual artifacts with realistic embedded text and layouts, creating a new misinformation threat: synthetic credibility. We introduce SYNCRED-Bench, a benchmark of 600 AI-generated misinformation images balanced across six credible-form categories and seven fine-grained circulation styles, together with FP450, a real-image negative set for measuring false positives. Extensive evaluation shows that existing systems remain unreliable: under a 5% false-positive-rate constraint, 15 MLLMs achieve only 10.5% true positive rate (TPR), open-source AIGC detectors achieve less than 5%, and commercial APIs reach 57.6%. Human annotators also struggled to identify synthetic credibility, reaching only 63% TPR. These findings establish synthetic credibility as a severe and underexplored visual misinformation challenge, and provide a benchmark for developing detectors that reason beyond superficial credibility cues.

As autonomous vehicle capabilities advance, the safe evaluation of driving policies in long-tail scenarios remains a critical bottleneck. In closed-loop simulation, the driving policy model actively interacts with the environment, where its actions dynamically update the simulator state and directly influence the next set of generated sensor observations. While recent reconstruction-based neural simulators offer photorealism, they are fundamentally constrained by their initial captured data and struggle to generalize to highly dynamic or novel scenes. To overcome these limitations, we introduce OmniDreams, a foundation generative world model mid- and post-trained from the Cosmos diffusion model to autoregressively generate action-conditioned videos in real time. By leveraging the rich visual priors of Cosmos and mid- and post-training on 21k hours of driving scenarios, OmniDreams synthesizes complex, unobserved phenomena that are hard for traditional simulators to capture, such as extreme weather and unpredictable dynamic agent behaviors. Crucially, it autoregressively conditions its photorealistic sensor generation on past frames, the current simulator state, and immediate driving actions. Deployed in a closed-loop system with the Alpamayo 1 policy model and AlpaSim orchestrator, OmniDreams acts as a highly responsive, reactive environment, providing a scalable and comprehensive solution for training and evaluating next-generation autonomous driving policies. We additionally show preliminary results indicating that a world-action model (WAM) post-trained from OmniDreams achieves strong performance on the Physical AI Autonomous Vehicles NuRec dataset, surpassing the VLA-based Alpamayo 1.5 research policy model while using only 1/5 the total parameters. These results highlight the potential for a real-time world model like OmniDreams to also serve as a backbone for policy architectures.

Guidance methods, such as classifier-free guidance (CFG) and auto-guidance (AG), have advanced noise-to-data generation in diffusion models. Recently, bridge models have introduced a data-to-data generative process that can exploit an instructive clean prior. In this work, inspired by previous methods creating quality difference between denoising results as guidance, we propose a training-free bridge guidance method, termed Prior Guidance (PG). Specifically, we introduce a weak prior, which is unseen during bridge pre-training, hindering prior exploitation and thereby degrading denoising result. Then, we contrast it with the seen prior to highlight and enhance prior exploitation via a scaling factor. Moreover, we analyze the underlying mechanism of prior exploitation in the bridge process and design frequency-modulated prior guidance (FMPG), which tailors the guidance scale to low- and high-frequency bands coherent with bridge generative dynamics. To address prior exploitation in image in-painting, we develop a cascaded framework, CFG-FMPG, which first generates a noisy hidden representation via CFG and then exploits it as a generative prior with FMPG, fulfilling their complementary strengths without compromising inference efficiency. Experiments demonstrate that our PG methods consistently improve pre-trained bridge models across diverse image translation tasks.

We present a diffusion-based method for relighting dynamic portrait videos with photorealism and temporal consistency. Our method is fueled by a hybrid training dataset that consists of real-captured and rendered dynamic portrait videos with diverse subject appearances, facial motions, head poses, and known lighting conditions. Specifically, we construct an LED-based lighting system for realistic lighting emulation and high-speed video relighting data acquisition. By leveraging the image priors embedded in pre-trained video diffusion models, and using per-frame high dynamic range (HDR) environment map as lighting control, we train a high-performance generative model for realistic and identity-preserving dynamic portrait video relighting. In addition to the environment map control, our model uses a synthesized background image to enable control on the camera's exposure level and color tone. Our model can produce temporally consistent relit portrait video that looks realistic and harmonious under a provided new environment and faithfully preserve the subject's expression and fine facial features, including skin tone, wrinkles, and facial hair. Our model generalizes well to unseen data, in terms of the subject appearance, motion, and lighting condition. We perform extensive experiments on relighting in-the-wild videos with various environment maps and demonstrate practical applications on portrait photography. Results show that our method achieves state-of-the-art performance in photorealism, lighting harmony, and temporal consistency.

In this study, we conduct a comprehensive comparative analysis of generative and discriminative deep learning-based speech enhancement methods, specifically in noise reduction tasks. Our investigation focuses on evaluating their effectiveness under high and low signal-to-noise ratio conditions, considering both matched and mismatched training scenarios. We further investigate the impact of training data volume, model convergence speed, and interpret the performance differences in terms of objective results for the considered training paradigms. Additionally, we compare the complexity-performance trade-off and the practical viability of these approaches. To further strengthen the evaluation, we study the hallucination characteristics of generative approaches in terms of word error rate and phoneme similarity. The insights derived from this study provide empirical evidence to assist researchers and practitioners in understanding whether the perceptual gains of different approaches justify their computational cost in practical applications.

Retrieval-augmented generative agents rely on retrieval for grounding, yet are typically evaluated on a query-by-query basis. This isolates interactions that are geometrically coupled in a shared embedding space. For example, we show that the high document density required to serve majority interests (e.g., generic "Crime" movies) can geometrically overcrowd the retrieval neighborhood of a semantically similar minority (e.g., "Film Noir"), effectively expelling minority content from top-$k$ results. We introduce a formal framework to analyze how such goal collisions in dense retrieval induce fundamental performance limits and emergent fairness issues inherent to spatial crowding. In our static analysis, we demonstrate that for a fixed embedding space, a phase transition occurs where minority user goals suffer a catastrophic collapse in performance as the density of majority goals increases. We then extend this to a dynamic model and derive a non-linear Fokker-Planck equation that governs the evolution of document embeddings as the agent updates them to maximize retrieval accuracy. Our analysis reveals that this local relevance objective triggers an emergent global mechanism that systematically marginalizes minority interests. We prove that such objectives drive the system to self-organize into a state that exclusively serves majority interests. These results provide a theoretical foundation for understanding a critical grounding failure mode in retrieval-augmented agents.

Large-scale generative models have demonstrated remarkable capabilities across image generation and editing tasks. However, their performance in low-level vision tasks, which require pixel-wise control, remains insufficiently studied. To address this gap, we introduce \textbf{LL-Bench}, a comprehensive \textbf{Benchmark} for evaluating the capabilities of large-scale generative models on \textbf{L}ow-\textbf{L}evel vision tasks. The benchmark comprises 2,469 real-world degraded images covering 16 low-level degradation tasks, and 28,919 restored images produced by 10 state-of-the-art large-scale generative models and 21 conventional restoration models, which are annotated with 152,020 expert-level pairwise human preferences and 28,334 quality scores. Built upon LL-Bench, we present a systematic diagnosis that reveals the performance boundaries and unique failure modes of large-scale generative models across diverse low-level vision tasks, compared with conventional representative restoration approaches. Moreover, we investigate the effectiveness of current quality evaluation metrics on LL-Bench, which exhibit significant discrepancy with human ratings. To better align restored-image quality assessment with human preferences, we further propose \textbf{LL-Score}, an MLLM-based evaluator that captures both restoration quality and hallucination existence. Extensive experiments demonstrate that LL-score not only outperforms existing image quality assessment metrics, but also serves as a promising reward model for training generative models on low-level vision tasks.

One-step text-to-image generators are attractive for deployment because they generate an image with a single forward pass, but preference finetuning them remains difficult: standard alignment methods often rely on policy likelihoods, denoising trajectories, differentiable reward gradients, or test-time optimization. We propose Drifting Preference Optimization (DrPO), an online preference-finetuning method for deterministic one-step generators. For each prompt, DrPO samples candidates from the current generator, ranks them with a target reward, and uses high- and low-scoring samples to synthesize a feature-space update direction. The update is a non-parametric dipole preference field plus a reference drift estimated from the frozen base generator, and is optimized through a detached feature-space regression target. The target reward is used only for ranking, so DrPO can train with large, black-box, or non-differentiable rewards while inference remains a single generator call. We evaluate DrPO on SD-Turbo and SDXL-Turbo with multiple target rewards and benchmarks, including HPSv3 and GenEval. DrPO improves alignment over reward-gradient-free one-step preference baselines and reduces HPSv3 training computation by $3.51\times$ under the matched effective-batch setting by removing reward-model backpropagation. Initial offline experiments suggest that sample-based gradient synthesis can also be used beyond online reward ranking.

Inverse materials design is shifting materials discovery from forward prediction to targeted proposal of candidates that satisfy objectives under physical constraints. Here, we review recent advances in generative crystal structure modeling, multimodal learning, and closed-loop design pipelines for crystalline solids. We survey how modern generators learn chemical-structural priors from large databases to enable controllable sampling of periodic structures, and compare leading model classes including variational autoencoders, normalizing flows, autoregressive formulations, and diffusion models. Particular attention is given to how feasibility constraints and physical priors are enforced across the workflow, through representation choices, training objectives, sampling-time guidance, and post-generation screening and relaxation. We also discuss how multimodal learning fuses diverse materials modalities, including crystal structures, thermodynamic, electronic information, microscopy, spectroscopy, processing context, and scientific text, to construct a more universal, transferable representation of chemical space. In addition, diverse inverse-design strategies are examined, particularly those that integrate conditional generation with latent optimization, Bayesian optimization, reinforcement learning, and active learning. Finally, we highlight recurring failure modes, such as surrogate exploitation, diversity collapse, distribution shift, and the stability-synthesizability gap, and outline discovery-grade evaluation practices based on staged reporting of validity, novelty, uniqueness, stability, and cost.

Despite the remarkable fidelity of generative models, they frequently suffer from mode collapse. Existing strategies for enhancing diversity predominantly focus on intervening during the generation trajectory. We identify a critical oversight that the standard Gaussian initialization often causes trajectories to collapse into dominant modes because it is agnostic to the guidance potential landscape. In this work, we formulate selecting the initial noise from a guidance potential posterior, which effectively re-weights the prior towards diversity-rich regions. To sample from this distribution efficiently, we introduce Diversity-inducing Initialization (DivIn), which leverages Langevin dynamics to actively navigate the initialization landscape, steering initial noise away from collapsing regions while anchoring them to the valid data manifold. Our method serves as an inference-time diversity enhancement compatible with both diffusion and flow matching models. Extensive experiments show that DivIn exhibits a superior performance in both class-to-image and text-to-image scenarios. Furthermore, we highlight that as DivIn is orthogonal to trajectory-based methods, combining them significantly expands the diversity-quality Pareto frontier beyond what either achieves in isolation.

Generative artificial intelligence (AI) systems open new possibilities for experimentation in literary studies via controlled, grounded, large-scale, low-cost simulations of cultural production. Current systems have not yet been shown to produce high-quality, book-length narrative texts that reliably reflect arbitrarily specified cultural constraints or stylistic features. But there exists substantial relevant research on each of the components required for literary-historical simulation. These include the use and validation of AI systems as proxies for differentiable human populations; the narrative and stylistic properties of AI-generated texts; the stability and coherence of multiagent, multiturn AI simulations of human actors; and technical methods through which to alter in predictable ways the knowledge and behavior of generative systems. Together, these areas could provide a starting point for more ambitious AI-based modeling of cultural systems of literary production. We describe the possibilities and challenges of simulation-based experiments in literary studies, summarize the current state of the art in relevant fields, and explain key technical aspects of the work. To provide an example directly relevant to literary scholars, we present the results of experiments on literary text generation, including comparisons to high-status, human-authored novels. Our results include the first demonstration of (limited) in-distribution outputs by AI models in this domain. We conclude with a description of future work on full counterfactual literary-historical simulations using AI.

Estimating the generative mechanism of large-scale networks is a fundamental challenge in statistical machine learning. It requires the identification of the latent connectivity structure, which is in general an NP-hard combinatorial problem due to the absence of canonical node labels. We address this challenge by allowing for probabilistic couplings, thereby relaxing the assignment problem. Our estimation framework can be formulated as a semi-relaxed Gromov-Wasserstein objective and provides a low-dimensional representation of the generative structure. We solve this via a block-coordinate conditional gradient algorithm. Despite the relaxation, the resulting solution is typically deterministic: in fact, we show that the optimality gap between the relaxed solution and the deterministic assignment vanishes at rate $O(1/n)$, where $n$ is the number of nodes. This allows for tractable recovery of the underlying model and enables rigorous statistical analysis: we establish consistency and minimax-optimal convergence rates for both stochastic block models and Holder-smooth graphons. Our implementation scales efficiently with $n$, as demonstrated on both synthetic and real-world datasets.

Background: Respiratory sound classification plays a critical role in the clinical identification of pulmonary pathologies. However, its performance is often hindered by the limited size, severe noise, and class imbalance of real-world auscultation datasets. Although conventional audio augmentation techniques are easy to implement, they may inadvertently distort subtle pathological characteristics. Meanwhile, existing Variational Autoencoder (VAE)- or Generative Adversarial Network (GAN)-based generative approaches often suffer from limited sample fidelity and insufficient controllability over class semantics, particularly under conditions of scarce supervision. Methods: To overcome these limitations, we propose C2GA, a class-controllable generative augmentation framework. C2GA first constructs a semantically rich discrete latent space using a conditional Vector-Quantized Variational Autoencoder (VQ-VAE), in which local acoustic tokens are explicitly decoupled from global class prototypes. Subsequently, a Transformer-based autoregressive prior is trained to generate label-consistent token sequences. These generated tokens are then fused with the corresponding class prototypes and decoded into high-fidelity Mel-spectrograms for data augmentation. Conclusion: These results indicate that C2GA provides an effective and semantically reliable augmentation strategy for respiratory sound analysis. By enabling controllable and high-quality data generation, the proposed framework offers a promising solution for improving the robustness and generalization of respiratory sound classification in realistic clinical scenarios.

This study investigates the trade-offs between fidelity, privacy, and utility in synthetic data generation under conditions of data scarcity and privacy sensitivity. We propose an evaluation framework that jointly assesses these three dimensions and apply it to three widely used generative models, VAE, GAN, and DDPM. The evaluation spans three image datasets, MNIST, OCTMNIST, and OrganAMNIST, encompassing both general-purpose and medical imaging domains. Notable differences arise between the three models in their behaviour when differential privacy mechanisms are introduced during training. GAN and DDPM demonstrate greater robustness, maintaining higher fidelity and downstream utility across a range of noise levels, while VAE degrades more rapidly as privacy constraints increase. This study highlights the importance of a multidimensional evaluation of deep generative models, also noting that their behaviour significantly differs when privacy techniques are applied.

Non-monotonic sequence generation methods, such as masked diffusion models, provide a flexible alternative to left-to-right autoregressive modeling by allowing tokens to be generated in non-fixed and prescribed orders. Despite their practical advantages, most existing non-monotonic models are order-agnostic and rely on a fixed-length grid, limiting their ability to support variable-length generation and adaptive insertion order. In this work, we introduce a probabilistic framework for learning insertion order in variable-length insertion models. We formalize a bijective correspondence between insertion trajectories and permutations, which enables an exact reparameterization of the data likelihood as a sum over permutations. Building on this result, we propose the Insertion Process (IP), a stochastic generative model that jointly learns where to insert, what to insert, and when to terminate, trained via permutation-based variational inference. Unlike prior fixed-canvas approaches, IP natively supports variable-length generation and learns data-driven preferences over insertion orders. Experiments on goal-conditioned planning and molecular string generation demonstrate that learning insertion order improves both modeling quality and generalization in domains without a canonical left-to-right structure.

Modern deep learning models for forecasting groups of time series rely on increasingly longer observation windows. However, the benefit of increasing the window size is often simply attributed to capturing long-range dependencies, and broader discussion on how global forecasting models leverage input observations has been limited. In this paper, we show that forecasting groups of time series involves two objectives: (i) generative process identification (GPI), i.e., inferring the specific process generating the input sequence, and (ii) conditional forecasting (CF), i.e., predicting future values given input observations. From this perspective, optimal predictions can be interpreted as an average over plausible data-generating processes, weighted by their likelihood given the input window. This suggests another explanation for the benefits of long context windows: they reduce the uncertainty about which specific process is generating the input time series during operation. We prove that even for processes with memory length $P$, an input window size strictly larger than $P$ is necessary to achieve the minimum attainable error. Finally, we show how decoupling GPI and CF can improve computational scalability without compromising accuracy. Experiments on synthetic and real-world data validate our insights and their relevance for designing forecasting architectures.

Implicit-process priors define distributions over functions through flexible generative mechanisms, making them attractive for Bayesian function-space modelling. However, performing posterior inference with such priors is challenging because their induced function-space distributions are typically not available in closed form. One practical strategy is to approximate the prior using a finite collection of sampled functions, and then represent posterior functions as learned combinations of these samples. Existing approaches commonly place a Gaussian variational distribution over the combination weights. While tractable, this choice limits the shapes of posterior uncertainty that can be represented, especially when the true posterior is asymmetric, heavy-tailed, or multimodal. We propose Flow-Transformed Implicit Processes (FTIP), a variational inference method that makes this finite-dimensional function-space approximation more expressive. Instead of using a Gaussian distribution over the combination weights, FTIP uses a normalizing flow to define a richer variational distribution. This induces a flexible posterior distribution over functions while preserving tractable optimization. We train the model using a Black-Box α objective, allowing us to compare mass-covering and mode-seeking variational behaviour. Experiments show that FTIP captures asymmetric and multimodal posterior structure in function space that Gaussian coefficient approximations tend to smooth or collapse.

Mosquito-borne infectious diseases cause more than 700000 deaths worldwide each year. The long-term use of conventional chemical insecticides has induced serious resistance problems, creating an urgent need to develop novel, highly effective, and ecologically sustainable alternatives. While existing artificial intelligence approaches in this domain have focused primarily on activity prediction and classification, they leave a critical gap in the de~novo generation of novel molecular scaffolds. In this study, we propose Mos-Gen, a motif-aware generative collaborative framework that couples the pretrained molecular representation model Uni-Mol with a variational autoencoder (VAE), specifically tailored for the design of disulfide-containing allicin derivatives as mosquito insecticides. Among the generated candidates, fourteen compounds -- comprising nine predicted positives and five predicted negatives -- were selected for chemical synthesis and experimental validation. The hit rate among the predicted positives reached 78%, whereas none of the predicted negatives exhibited mosquitocidal activity. These experimental results fully validated the high-precision screening capability of the Mos-Gen framework.

We address the challenge of generating high-fidelity, long-form soundtracks that remain coherent across scene transitions. Existing AI music systems are mainly designed for short, isolated clips and lack mechanisms to ensure narrative continuity. We present JenBridge, a modular and interpretable framework for adaptive long-form video soundtracking that ensures both high-fidelity audio generation and transition naturalness. The core architecture is a Transformer-based generative model trained with a flow-matching objective, following a two-stage paradigm: pretraining on large-scale text-audio corpora to establish robust musical priors, then adapting to the video domain with dual text-visual conditioning for precise cross-modal alignment. Crucially, to achieve long-form coherence across diverse scene changes, JenBridge incorporates a novel adaptive transition mechanism. This system features a versatile toolkit of transition styles, including a generative transition method, and uniquely employs a Large Language Model (LLM) Agent that acts as a director to select the most appropriate transition for each narrative shift intelligently. To rigorously assess this task, we propose the LVS Benchmark, a new benchmark that includes a curated dataset and novel evaluation metrics focusing on holistic and transition-aware assessment. Extensive experiments on the proposed benchmark demonstrate that JenBridge significantly outperforms existing methods in both objective and subjective metrics, particularly in terms of transition naturalness and overall narrative coherence. JenBridge represents a significant step towards fully automated, professional-quality video soundtracking.

Image generative models, though widely used as creative tools, offer limited support for the kind of compositional control that photographers and visual artists routinely exercise. This paper presents early results on an anchor conditioned finetuning framework for landscape image generation, in which a four dimensional compositional anchor vector is extracted from training images and injected into a diffusion model via a decoupled cross attention mechanism with Fourier encoding and three way classifier free guidance dropout. Quantitative evaluation against a baseline and three ablation variants shows that the proposed architecture achieves the highest horizon detection rate of 0.850 and the highest rule of thirds alignment of 0.817. A category specific ablation further demonstrates that training on compositionally homogeneous scene subsets reduces horizon deviation by up to 40 percent compared to mixed training. This establishes that compositional control precision is category dependent.

Diffusion models have emerged as a leading framework for deep generative modeling. While the standard Gaussian formulation is theoretically convenient, its suitability for heavy-tailed datasets remains unclear. To address this, heavy-tailed diffusion models (HTDMs) extend the standard formulation by replacing the Gaussian distribution with a Student's t-distribution, thereby improving tail fidelity on heavy-tailed datasets. Although stochastic differential equation (SDE)-based sampling is possible in HTDMs, it has not been fully explored. In this paper, we propose an SDE-based sampler for HTDMs that explicitly incorporates a state-dependent diffusion coefficient. This state dependence naturally induces a self-regulating annealing mechanism by adaptively modulating the effective noise scale. We theoretically explore this mechanism and experimentally verify its necessity for reproducing samples from a heavy-tailed distribution.

Biomolecules such as proteins and small-molecule ligands play a central role in biological systems, arising from the tight interplay between sequence and three-dimensional structure. Recent generative models for biomolecular co-design aim to capture this interplay by jointly modeling coupled modalities. However, existing approaches largely adopt a parallel execution of marginal generative processes, implicitly enforcing fixed synchronous coupling. We argue that a critical but overlooked degree of freedom lies in how these marginal processes are temporally coupled during training and generation, where inappropriate coupling can introduce high-variance supervision and inconsistent intermediate states, affecting modality consistency. To address this, we introduce GeoCoupling, a systematic framework that optimizes for temporal couplings between heterogeneous modalities. Empirical results across structure-based drug design and unconditional protein design demonstrate the learned couplings consistently outperform synchronous and randomly coupled baselines, yielding biomolecules with improved physical validity and diversity.

Data scarcity in multimodal pathology motivates unified generative models that synthesize modality-specific appearance while preserving anatomically coherent structure. Although modalities differ in appearance statistics, morphological structures such as cellular topology and tissue boundaries are largely preserved across acquisition protocols. However, existing methods often model these factors within a homogeneous token stream, implicitly coupling structure with appearance and weakening structural controllability under modality shifts. To address this, we propose pathology Autorgressive modeling (PathAR), a structure-first autoregressive synthesis framework that explicitly factorizes structure and appearance for modality-label-conditioned pathology generation.PathAR employs a dual vector quantization (Dual-VQ) tokenizer to decompose samples into mask-grounded structure and appearance tokens, and an interleaved autoregressive (IAR) transformer with asymmetric attention visibility to enforce structure-to-appearance dependence. PathAR stabilizes morphology under heterogeneous modality-specific appearances and enables spatially aligned image--mask pair generation. Extensive experiments show that PathAR improves structural consistency and modality fidelity over baselines, maintains sample diversity, supports downstream segmentation in data-scarce regimes, and demonstrates extensibility to finer-grained intra-modality organ-label variation.

Hard negative mining has become the dominant strategy for training retrievers, yet it faces intrinsic limitations: negatives are bounded by corpus availability, selected by retriever score rather than diagnostic value, and increasingly contaminated by false positives as the retriever improves. LLM-based synthesis offers a principled alternative, where negatives that are unconstrained, targeted, and free from false positive risk. But we show that naively incorporating generated negatives into contrastive learning often degrades retrieval performance. We identify and formalize the root cause as a generative-discriminative gap: LLM generation optimizes for fluent, plausible text, while contrastive learning demands strategic violations of relevance at the decision boundary. Our analysis reveals two compounding failure modes: discriminative-agnostic generation, where the LLM lacks an explicit model of query information needs and defaults to generic or topic-drifted text that provides no contrastive signal; and source-dependent shortcuts, where distributional artifacts enable the model to distinguish negatives by origin rather than relevance, causing gradient drift that actively corrupts optimization. To close this gap, we propose CausalNeg consisting of two main modules: (1) CoT-guided counterfactual perturbation for data construction: decomposes why a document satisfies a query into explicit information requirements, then surgically violates individual requirements to construct negatives with controlled, interpretable hardness. (2) Query-view entropy maximization during training: disperses generated negatives across the similarity spectrum, minimizing the mutual information between source identity and similarity scores to suppress shortcut exploitation. We make our code publicly available at https://github.com/mzhangzhicheng/CausalNeg.

Audio-driven talking-head generation has advanced rapidly, yet existing evaluation protocols mainly rely on frame-wise metrics that assume strict temporal correspondence between generated and reference videos. This assumption does not match speech-driven facial motion, which naturally includes slight timing shifts, different speaking speeds, and stylistic variations. As a result, conventional metrics may treat harmless timing differences as quality errors, making it harder to fairly compare methods and understand their trade-offs. In this work, we argue that evaluation of dynamic generative models should be formulated as a sequence-alignment problem rather than independent frame comparison. We introduce a unified sequence-level reformulation that integrates Soft Dynamic Time Warping into established evaluation pipelines. By aligning feature trajectories while preserving temporal order, the proposed framework provides robustness to bounded temporal misalignments without altering the underlying perceptual, identity, or synchronization encoders. We show that frame-wise evaluation can be viewed as a special case under rigid alignment, while sequence-level alignment provides improved stability, lower sensitivity to timing differences, and clearer separation between modeling paradigms. Building on this principled formulation, we conduct a large-scale benchmark of 20 methods across seven datasets spanning canonical, in-the-wild, and style-diverse scenarios under standardized protocols. Extensive experiments show that temporally aligned metrics are more robust to timing differences, provide more consistent results across datasets, and better reveal systematic trade-offs between modeling paradigms, such as synchronization versus realism and expressiveness versus stability.

We address the problem of out-of-distribution (OOD) detection for target observations embedded in a subspace of the high dimensional data space. Using continuous normalizing flows (CNFs), we propose a Lagrangian sub-flow (LSF) framework designed to isolate and estimate the density for the relevant components in the representation and using the remaining components as context. Through experimentation with models for speech synthesis, we show that CNFs, similarly to other deep generative models (DGMs), are susceptible to the "likelihood paradox", where high likelihood is erroneously assigned to OOD samples. This is attributed to the inductive bias of DGMs that prioritize low-level structural details over high-level semantic coherence. To mitigate this phenomenon, we propose a number of geometric diagnostic signals based on the velocity field over the sub-flow trajectory. Based on these signals, we design metrics for the challenging task of zero-shot phoneme-level mispronunciation detection. Finally, we demonstrate the superiority of these metrics compared to likelihood-based methods on a real-world mispronunciation detection benchmark.

Transition metal complexes are central to catalysis, drug design, and materials science, with relevant properties strongly sensitive to their three-dimensional geometry. However, the electronic diversity and unconventional bonding environments of transition metal complexes pose a major challenge for accurate structure generation. In this work, we introduce TMCgen, a manifold diffusion machine learning model that efficiently and accurately generates geometries of transition metal complexes. By formulating the diffusion process over the metal-ligand coordination angles, combined with torsional and rotational diffusion of the ligands, TMCgen focuses on the key geometric degrees of freedom of transition metal complexes. TMCgen shows strong performance in generating accurate coordination environments on a diverse set of experimentally derived bioinorganic and organometallic complexes while requiring only few inference steps, enabling efficient generation. Our results demonstrate the potential of manifold-based generative modeling for data-efficient geometry generation, paving the way for property-conditioned design of transition metal complexes.

Generative models have emerged as a powerful paradigm for AI planning, yet their performance remains constrained by the training data distribution. One approach is to improve generated solutions during inference by scaling test-time compute. A more efficient alternative is to optimize the inference process itself. In this paper, we show that a modified version of a classical Open-Closed List (OCL) search provides just such an efficient inference procedure. Our algorithm synergizes two learned components: a generative model that performs fast rollouts from intermediate states and a heuristic model that prioritizes among candidate reasoning paths. Key contributions include novel exploration control mechanisms and integration of learned models within the OCL framework. Across multiple combinatorial planning domains, our approach outperforms both neurosymbolic search baselines and classical solvers in computational efficiency and solution quality.

Modern generative machine learning (ML) models can propose novel inorganic crystalline materials with targeted properties; however, synthesis planning of these materials remains difficult due to the complexity of the associated physical processes and limited availability of computational tools. We introduce a novel hybrid framework to evaluate Large Language Models (LLMs) in inorganic synthesis planning by combining thermodynamic databases with simplified kinetics models to approximate realistic synthesis conditions. As a case study, we focus on the niobium-oxygen system, which features multiple industrially relevant oxide phases with well-characterized data. In computational simulations, we compare LLM-generated synthesis routes with classical path-planning algorithms, showing that the implicit priors in LLMs can yield more viable strategies. In our evaluation setting, classical search methods serve primarily as a foil rather than a direct competitor. This illustrates the relative complexity of the problem and highlights where the LLM's implicit priors add value.

Generative machine learning is an increasingly important complement to dynamical downscaling for producing high-resolution precipitation projections, with diffusion models currently the leading approach. Flow matching is a related generative framework that has recently achieved strong results across image, video and other domains, and shown early promise for downscaling. We train a flow matching model to map daily precipitation from 8 km to 2 km over a convective-scale domain centred on Singapore, and benchmark it against CPMGEM, a score-based diffusion model. Flow matching achieves consistently better spatial skill: higher fractions skill score at every precipitation threshold and neighbourhood scale tested, and tighter structure and amplitude components of the SAL score with comparable location skill. However, flow matching underestimates the upper tail of the precipitation distribution, resulting in a dry bias in the climatological mean. These results suggest that flow matching is a competitive generative framework for convective-scale precipitation downscaling, particularly well suited to capturing spatial structure.

Unified multimodal models (UMMs) aim to handle perception and generation in a single model. Yet existing UMMs still rely on a frozen, separately pretrained VAE for image generation, imposing a structural bottleneck. Naively removing it introduces a quality gap, as the model must learn both high-level structure and low-level details from raw pixels. In this paper, we propose Representation Forcing (RF), a technique that closes this gap by making representation prediction a native capability of the model. Concretely, RF forces the decoder to autoregressively predict visual representations as intermediate tokens before pixels; these tokens then stay in context to guide pixel diffusion within the same backbone. By turning representations from perception outputs into generation targets, RF eliminates the need for any external generative latent space. We find that RF benefits both understanding and generation. On image generation, our pixel-space model with RF matches state-of-the-art VAE-based unified models. On image understanding, pixel-space RF generally outperforms its VAE-based variant. Together, these results offer an effective step toward end-to-end, bottleneck-free UMMs.

Reconstructing the complete geometry of a scene from a single RGB image remains challenging - especially when inferring hidden structures where visual evidence is incomplete. We introduce VolFill, a generative framework that predicts the 3D structure of the complete scene rather than relying on traditional pixel-aligned regression. Our method utilizes a hybrid 3D VAE to compress sparse truncated unsigned distance function grids into a compact latent space, paired with a latent Diffusion Transformer that denoises this representation to recover the complete scene. We condition the generation on geometry foundation models, leveraging rich spatial priors for robust reasoning. Unlike existing methods limited by per-ray constraints or unstructured point-cloud queries, VolFill provides a structured representation that supports direct surface extraction and occupancy queries at scale. Extensive experiments on the SCRREAM and NRGB-D datasets demonstrate that our approach significantly outperforms current baselines, providing a robust foundation for holistic spatial understanding.

Therapeutic mRNA design requires coordinating multiple interacting sequence features across the full transcript, where codon usage, untranslated regions (UTRs), and their coupling jointly determine stability, translation efficiency, and protein expression. Here, we present mRNA generation via unrolled trajectories and informed latent updates (mRNAutilus), a framework for simultaneous codon optimization and de novo UTR design directly from sequence. mRNAutilus combines a masked discrete diffusion model trained on millions of full-length mRNAs with Monte Carlo Tree Guidance to generate Pareto-efficient sequences under multiple functional objectives, using lightweight regressors over model embeddings to predict half-life, translation efficiency, and protein abundance. Unlike recent methods that design coding sequences and UTRs separately or rely on post hoc assembly and screening, mRNAutilus generates complete transcripts in a single process optimized across properties. Across diverse targets, zero-shot mRNAs encoding P. pyralis luciferase achieve over 400-fold higher expression than wild-type and outperform commercial and machine learning-designed baselines, including zero-shot generative approaches. Zero-shot SARS-CoV-2 Spike mRNAs exceed clinically used and commercial constructs and match or surpass lab-optimized designs with improved durability. We further demonstrate generality in therapeutic settings, including prime editing (PEMax) and programmable proteome modulation, where mRNAutilus-designed constructs enhance expression of peptide-guided E3 ligases (uAbs) for beta-catenin degradation. These results establish a sequence-based, multi-objective framework for generating functional mRNAs tailored to diverse biological applications.