Missing-Modality Learning

Multimodal brain tumor segmentation typically leverages multiple MRI modalities, yet incomplete modality acquisition is common in clinical practice due to protocol heterogeneity and scan failures. Although recent methods maintain segmentation accuracy under missing modality conditions, they frequently overlook prediction reliability, leading to miscalibrated confidence estimates that hinder clinical adoption. Existing calibration techniques are largely modality-agnostic or assume that prediction difficulty decreases monotonically as additional modalities become available. However, in brain tumor segmentation, prediction difficulty depends primarily on which modalities are absent rather than how many, leading to combination-specific and spatially heterogeneous calibration errors. To address this, we propose Missing Modality-Aware Local Temperature Scaling (MMA-LTS), a post-hoc voxel-wise confidence calibration method. It estimates a spatially adaptive temperature field conditioned on a modality-availability learnable token and a voxel-wise difficulty score. Experiments on BraTS 2020 and FeTS 2024 show that MMA-LTS improves calibration while preserving the segmentation accuracy of state-of-the-art models across diverse missing-modality scenarios, thereby enhancing trustworthiness toward clinical deployment.

Public mobile and wearable mental-health datasets often provide summarized feature tables rather than synchronized raw sensor streams. In these releases, each anchor corresponds to a survey or label time and may combine phone or wearable summaries, prior symptom scores, demographics, clinical variables, and source-availability indicators. We propose the Modality-Conditioned Temporal Recursive Context Model (MC-TRCM), which preserves each feature source as a separate token and incorporates missingness as part of the input context. Observed sources are encoded with values and missingness summaries, absent sources use learned absence tokens, dataset and task embeddings condition fusion, and a recursive prediction head refines each output over validation-selected steps. We evaluated MC-TRCM on six predefined endpoints from DepreST-CAT and Prediction of Severity Change-Depression (PSYCHE-D) using participant-level splits and validation-only model selection. MC-TRCM achieved the lowest mean absolute error on DepreST-CAT Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) severity, improving over the best tabular reference by 0.181 and 0.217 scale points. Classification endpoints showed task-dependent behavior: MC-TRCM matched the best rounded GAD-7 category balanced accuracy, was numerically highest by 0.002 balanced-accuracy points on PSYCHE-D multiclass prediction, and remained close to the strongest references on PHQ-9 category and PSYCHE-D binary prediction. Ablations support Feature-wise Linear Modulation, absence tokens, missingness projections, and recursive refinement, while calibration and feature-source controls characterize endpoint behavior. Our code is available at https://github.com/Botwwt/MC-TRCM.

Multimodal Alzheimer's disease (AD) diagnosis benefits from integrating heterogeneous clinical, imaging, genomic, and biomarker evidence, but clinical cohorts frequently suffer from irregular modality missingness. Existing fusion methods often synthesize absent inputs, risking the introduction of artificial surrogates, or pool available signals into uninterpretable latent spaces. We present CoPoE (Disease-Coordinate Product-of-Experts), a disease-coordinate framework that maps multimodal evidence into a structured latent space partitioned into four distinct biological and clinical axes: genetic Risk, molecular Pathology, Neurodegeneration, and clinical Stage (R/P/N/S). Each observed modality parameterizes a diagonal Gaussian expert over the full RPNS vector, and a masked Product-of-Experts architecture fuses only the available modalities. Consequently, absent modalities add no factor to the fusion path, allowing the network to preserve a robust, decomposable posterior for any non-empty modality subset without synthetic imputation in the RPNS path. Through extensive missing-modality experiments on the ADNI dataset, CoPoE achieves the best all-modality performance and the highest mean AUROC across all 15 observed-subset evaluations among standardized missing-modality fusion baselines under a shared non-PET ADNI embedding benchmark, while substantially improving raw-probability ECE, Brier score, and NLL. Furthermore, PET-supervised probing shows evidence enrichment within the pathology (P) block under full modalities, with tau-related signal retained even when direct fluid biospecimen inputs are withheld. Our code is available at https://github.com/labhai/CoPoE.

Imitation learning policies that integrate multiple sensory modalities are prone to overreliance on a dominant modality, such as vision, during training, which can disrupt policy execution when that modality is lost at inference time. In this paper, we introduce Targeted Modality Dropout (TMD), in which the dependence on each modality is estimated using attention and the most dominant modality is selectively dropped. This is combined with entropy regularization over the dependence distribution. Through real-robot evaluation using a bimanual manipulator, we show that under vision loss the success rate of the baseline policy drops substantially, whereas TMD sustains task execution. In contrast, a conventional dropout that selects the dropped modality at random, without the entropy regularization, fails on many tasks even without vision loss.

Audio-visual models improve egocentric action recognition by exploiting complementary cues, yet typically assume that both streams remain available at inference. Existing missing-modality methods operate on trimmed, single-event clips in which a stream is entirely present or absent, whereas real sensors fail and recover within long, untrimmed observations. We redefine egocentric modality missingness as temporally localized sensor outages within untrimmed, multi-event observations, with whole-clip absence as the limiting case. We introduce \textbf{MacJEPA}, a missing-modality-robust \textbf{Ma}sked-\textbf{c}ontext query \textbf{JEPA} that recognizes visual actions and acoustic events from supplied interval queries over audio-visual context. Window-local modality dropout simulates these sensor outages during training. MacJEPA further repurposes masking in JEPA from a self-supervised pretext into a supervised robustness objective, aligning masked and clean latent representations of both multimodal content tokens and the task-conditioned queries. All objectives are optimized jointly with recognition in a single stage, requiring no test-time adaptation. Across Epic-Kitchens-100 and Epic-Sounds, a single checkpoint remains competitive under complete input and consistently surpasses published missing-modality baselines when either the dominant or auxiliary stream is removed. MacJEPA thus unifies strong full-input recognition with temporal missing-modality robustness in a single model operating on untrimmed multi-event videos.

Multimodal wearable systems must remain reliable when sensor streams become noisy or unavailable. Existing multimodal test-time adaptation (TTA) methods often assess reliability online, but cross-modal agreement can be misleading when sensors measure different physical processes, and evaluating alternative modality configurations adds inference cost. We propose CARAT, which decouples model reliance from runtime corruption detection to guide omission or attenuation, amortizing reliance estimation through source training. An asymmetric modality-dropout curriculum prepares a missingness-resilient backbone for omission and derives a frozen, backbone-specific reliance proxy from windowed input-projection gradient norms. At deployment, a lightweight one-class detector flags suspect streams, and the proxy guides a joint choice between replacing the suspect set with the backbone's trained missingness symbol and attenuating its representations before fusion, without candidate-subset evaluation. Across four wearable datasets, five corruption types, three backbones, and eight TTA baselines, CARAT achieves the highest overall macro-F1 and best mean rank (2.42), exceeding EATA, the strongest baseline, by 1.58 F1 points across 12 equally weighted dataset-backbone settings. Across five profiled configurations, CARAT uses 9.49% fewer GFLOPs and updates 47.82% fewer parameters than EATA. A pattern also emerges across sensing regimes: multimodal TTA methods such as PTA are competitive on IMU-dominated homogeneous datasets, whereas unimodal TTA methods like TENT and EATA match or exceed it on heterogeneous datasets. These results position CARAT as a practical default to wearable TTA, offering competitive robustness with modest computational requirements and benefits that vary across backbones and dataset regimes.

The high cost of functional molecular assays, and prevalence of missing modalities and unmatched samples in computational biology, create significant barriers to comprehensive multi-omic profiling, essential for capturing and reasoning over molecules, cells, tissues, and organisms. This work proposes a model that learns meaningful representations from multi-omics cancer data supporting the reconstruction of missing and unpaired modalities. Contrary to increasingly complex, larger models, e.g. Foundation Models (FMs), ARO prioritizes practical applicability in limited or incomplete data settings. ARO optimally reconstructs missing modalities (MSE of $0.15$ on the validation and test data in the Unmasked settings), with its learned latent embeddings enabling a downstream cancer classification task. Our findings indicate that analyzing diverse molecular layers as a single integrated system offers a reliable and cost-efficient approach, reducing dependence on large-scale experimental testing, while still supporting multi-omic exploration in limited data settings.

Longitudinal clinical cohorts are multimodal, irregularly sampled and pervasively incomplete: in ADNI, positron emission tomography and cerebrospinal fluid assays are absent from roughly half of all visits. Linear state-space models handle irregular sampling gracefully but treat a missing modality by masking the input, leaving the transition operator untouched. We prove that this is a representational limitation: the latent state of any linear state-space layer whose transition operator does not depend on the availability pattern is an additive function of the availability indicators, so no such layer can represent an interaction between two modalities being jointly present or jointly absent. We propose CAMOS, which gives each modality a bank of second-order oscillators coupled through a matrix that sits inside the differential equation and is gated by availability, so the transition operator itself becomes a function of which measurements were taken. Coupling invalidates the analysis of uncoupled oscillatory models, and we restore it: a per-channel Gershgorin budget makes the effective stiffness positive definite uniformly over all $2^M$ availability patterns and all gaps, an energy argument charges amplification to availability transitions rather than sequence length, and a channel factorization preserves exact associative parallel scans. On ADNI, CAMOS outperforms uncoupled oscillatory state-space models and clinical fusion models on same-visit staging, landmark prediction and longitudinal forecasting, and under zero-shot transfer to OASIS-3 it is the only model that avoids collapse to the majority class.

Existing multimodal video highlight detectors typically assume that visual, audio, and textual streams are continuously available. In practice, however, inputs may suffer from localized frame missingness or complete-stream outage. We formulate this robustness challenge along two dimensions: temporal missingness, where frames are missing independently in each modality, and stream-level missingness, where one modality is unavailable throughout a video. Moreover, we find that the mean squared error (MSE) loss is misaligned with both the evaluation metrics and the peak-driven nature of highlights. Therefore, we propose Temporal-Stream Modality Dropout (TSMD), which combines structured missingness simulation with a joint objective comprising pointwise MSE, per-video Pearson correlation, and peak-oriented RankNet loss terms. TSMD has three variants: temporal, stream-level, and mixed dropout. On the MoSu and Mr. HiSum datasets, TSMD-Temporal improves mAP@15 by 7.06 and 3.41 points over TripleSumm under 50% independent temporal removal, whereas TSMD-Stream performs the best under complete-stream removal. TSMD-Mix retains most of these complementary benefits and ranks the best or the second-best across the evaluated temporal and stream-level conditions.

Unsupervised visible-infrared person re-identification (USL-VI-ReID) learns person representations that can be compared across modalities without identity annotations. In the unpaired setting, however, identity correspondences between modalities are often incomplete, leaving many identities without an observed counterpart in the other modality. Existing unpaired methods bridge this gap by generating or mapping features for the other modality, mainly by exploiting the statistics of visual features without explicitly separating content that is discriminative for identity from style that is specific to modality. Consequently, the generated features may distort identity cues or inherit bias from the source modality, undermining the reliability of supervision across modalities. We formulate unpaired learning across modalities as a semantic compensation problem and propose Semantic Modality Compensation (SMC), a framework based on prompt composition that decouples identity semantics from modality style within a shared visual semantic space. SMC first constructs a discriminative ReID space through augmented dual contrastive learning, yielding pseudo labels, cluster prototypes, and memory banks for each modality. It then learns visible and infrared modality prompts in the CLIP semantic space and maps clusters obtained from pseudo labels to identity semantic tokens. For each cluster lacking a reliable match in the other modality, SMC combines its identity token with the prompt for the target modality to synthesize a semantic counterpart in the missing modality. The synthesized counterpart is then projected back into the ReID space and injected into a compensation memory through confidence gating. Extensive experiments under both paired and unpaired settings demonstrate that SMC consistently outperforms state-of-the-art methods, with particularly large gains when identity mismatch is severe.

Recent research on Multimodal Sentiment Analysis (MSA) has focused on learning from language, visual, and acoustic modalities with incomplete data to infer human sentiment. Most studies typically compensate for missing information by reconstructing modality features or designing complicated fusion mechanisms. However, these methods still suffer from spurious generation and noisy guidance due to the lack of high-level semantic grounding in partially observed multimodal evidence. To address these issues, we propose SemMSA, a latent semantic-aided framework that constructs rich sentiment-relevant semantics with LLMs, fully integrating with all modalities via anchor-free spectral alignment. It mainly consists of Cross-modal Semantic Refinement (CSR) and Cross-modal Spectral Alignment (CSA). Specifically, CSR first adaptively extracts visual and acoustic representations by corresponding adapters to form a unified multimodal prefix with language in the frozen LLM embedding space. It then iteratively produces continuous discriminative semantic states through a token-efficient latent refinement process without decoding explicit text. Next, CSA simultaneously aligns the refined semantics with all modalities by enhancing the dominant spectral component of their kernel Gram matrix. This captures global nonlinear dependencies among all representations without relying on a predefined anchor modality. In addition, an instance-level spectral separation constraint preserves cross-sample discriminability and mitigates representation collapse. Extensive experiments on SIMS, MOSI, and MOSEI benchmarks demonstrate that SemMSA achieves state-of-the-art performance.

Clinical decision making heavily relies on predicting the disease progression trajectory by seeking to understand patient's health status which is characterised by multimodal medical data. AI holds great potential for learning useful representations from multimodal medical data to predict disease progression and aid clinical decision making. However, development of predictive AI models is constrained by missing modalities and incomplete tabular data frequently occurring in medical datasets. In addition, disease labels alone may only provide limited supervisory signals for learning representations from high-dimensional multimodal data. Here, we present MMAP, a novel Multimodal Missing-aware Alignment Pretraining method for learning image-tabular representations from incomplete data. An image encoder is pretrained with efficient sigmoid contrastive learning combined with generative reconstruction. A tabular encoder is built upon a tabular foundation model. A missing token generator enables the two encoders to take incomplete data as input, enabling the model to be robust against missing modalities, either with missing images or missing tabular data. We evaluate the clinical usefulness of the learnt multimodal representations on two challenging longitudinal clinical tasks for Alzheimer's disease: predicting disease stage conversion and predicting amyloid status. The proposed method outperforms strong multimodal and unimodal baselines.

Clinical multimodal models must often predict before all chest X-ray (CXR) and electronic health record (EHR) inputs are available. Existing approaches align observed representations, model missingness, or reconstruct across modalities, but do not jointly exploit within-patient and clinically similar inter-patient evidence. We propose GLR-MM, a Graph-Based Global-Local Reconstruction framework for early ICU mortality prediction. It maps five CXR-EHR modalities to a shared space, reconstructs missing embeddings through complementary local cross-modal and global graph-attention branches, adaptively fuses their estimates, and optimizes class-balanced prediction, reconstruction, and contrastive objectives. On 9,620 MIMIC-derived ICU stays, we evaluate 10%, 30%, and 50% random modality missingness with shared deterministic masks. MUSE performs better under mild and moderate missingness, whereas GLR-MM achieves higher AUROC and AUPRC at 50% by 0.0088 and 0.0249, respectively. These results indicate that graph-guided reconstruction is most useful when inputs are severely incomplete.

Multi-modal spatio-temporal forecasting (MM-STF) supports weather nowcasting, traffic prediction, and earth-system modeling by combining heterogeneous sources such as physical fields, satellite imagery, and in-situ sensors. Three obstacles persist: (i) modalities have different spatio-temporal sampling rates, forcing lossy interpolation onto a unified grid; (ii) modalities are frequently missing at deployment due to sensor outages or revisit gaps, while most methods train with full availability; and (iii) autoregressive decoders accumulate errors over long horizons, amplified by multi-modal conditioning. We propose AsyncCouple-Flow to address these issues jointly. A Modality-Aware Token Sparsification (MATS) module performs scale-aware tokenization and uses a shared importance scorer to select top-k tokens per timestep, producing equal-length sequences. An Asynchronous Cross-Modal Coupling Graph (ACCG) replaces fixed cross-attention with a learnable graph whose edges encode time offsets, semantic similarity, and modality-specific physical priors, enabling fusion under arbitrary asynchrony and missingness. A Flow-Matching Forecasting Head models multi-step prediction as a conditional ODE, trained with stochastic modality dropout and integrated jointly to avoid autoregressive drift. Experiments on ERA5+GOES+ISD weather forecasting and PEMS-BAY traffic prediction with multi-source side information show that AsyncCouple-Flow outperforms state-of-the-art baselines and remains robust with up to two missing modalities. The code will be released upon acceptance.

Camouflaged object detection (COD) is an important engineering task in intelligent optical perception, but it remains challenging when targets closely resemble their surroundings. Polarization imaging provides complementary physical cues, whereas existing methods typically assume fixed multimodal input configurations and entangle intra-polarization coordination with interaction between red-green-blue (RGB) and polarization representations. We propose LGFN, a lightweight gated RGB-polarization fusion framework supporting separately optimized RGB-only and polarization-assisted configurations. A deterministic Modality Router selects the appropriate configuration according to polarization availability. In the multimodal configuration, an availability-conditioned Modality Gate calibrates the available polarization branches; the Gated Polarization Hub coordinates learned degree of linear polarization (DoLP) and angle of polarization (AoP) representations with explicit polarization cues; and RGB-Polarization Cross Fusion introduces the coordinated representation into the RGB hierarchy through controlled residual interaction. The multimodal configuration requires neither sample-dependent statistics nor handcrafted quality descriptors during inference. On the complete 230-image PCOD_1200 test set, the RGB-only configuration achieves a mean absolute error of 0.0090, a Dice score of 0.8806, and an intersection over union of 0.8144, obtaining the best results on all six metrics among the evaluated RGB-based methods. Under a common local reevaluation protocol, the multimodal configuration outperforms PolarNet and IPNet on all six metrics. Relative to IPNet, it reduces the parameter count, floating-point operations, and latency by 53.1%, 73.6%, and 63.0%, respectively.

Reliable small-molecule identification often requires complementary evidence from multiple spectroscopic measurements. In practice, however, spectra may be unavailable, degraded by measurement-related variations, or even incorrectly associated with a sample, thereby hindering accurate molecular identification. Herein, we propose a multimodal mixed-condition training strategy that accommodates missing, degraded, and mismatched measurements for small-molecule structure identification. The strategy incorporates chemical and spectroscopic knowledge through predefined missing-input configurations, modality-specific spectral perturbations, and chemically informed spectrum replacements. Models were trained on 635,441 samples comprising mass spectrometry (MS), infrared (IR), and nuclear magnetic resonance (NMR) simulated spectra from the Multimodal Spectroscopic Dataset (MSSD). They were then systematically evaluated on 79,462 held-out samples across 30 views designed to represent variations in spectra. A controlled comparison of complete-input and mixed-condition training under concatenation and mixture-of-experts (MoE) fusion showed that the training strategy was the principal source of improvement. For MoE, mixed-condition training increased the mean reciprocal rank (MRR) by 6.08% (from 0.9203 to 0.9763) and the top-1 molecular identification rate by 7.67% (from 89.50% to 96.36%). Notably, under single-modality inputs, IR MRR increased 2.15-fold (from 0.4337 to 0.9307), while MS MRR increased 2.31-fold (from 0.3711 to 0.8575). With the proposed strategy, complete-input performance remained high, while sample-level mismatch detection also improved. Together, these results highlight the potential of multimodal mixed-condition training for practical molecular identification by explicitly addressing incomplete, degraded, and mismatched measurements encountered in real-world analysis.

Recent multimodal sentiment analysis studies increasingly adopt text-centric fusion approaches to exploit the rich sentiment information inherent in the textual modality. However, these approaches often suffer from performance degradation during inference due to partially missing or noisy data in real-world scenarios, especially when sentiment-related cues are missing. To address this issue, we introduce a new completeness estimation approach that quantifies the degree of sentiment-relevant information preserved in incomplete data to guide the reconstruction of missing semantics. Furthermore, we propose a training strategy that stabilizes multi-task learning while jointly optimizing sentiment prediction and completeness estimation. Extensive experiments and in-depth analyses on three benchmark datasets demonstrate that the proposed approach enables more accurate semantic reconstruction, leading to more precise sentiment prediction.

Infrared-visible object detection (IVOD) integrates complementary evidence from visible and infrared sensors for reliable perception in challenging scenes. In practice, sensors may fail or drop frames, leaving one modality unavailable or intermittent. Existing methods for IVOD assume both modalities are always present, and fixed fusion collapses when one stream is missing. Furthermore, it remains a critical challenge to reliably estimate semantic correlation across heterogeneous modalities, especially under spectral distribution discrepancy. We present FlexibleFusion, a unified and adaptive method that flexibly allocates integration pathways and fusion strength, operating seamlessly across complete and missing-modality regimes. At its core, the Modality-Aware Experts Collaboration (MAEC) mechanism selectively activates and aggregates cross-modal or intra-modal expert pathways. It allows cross-modal fusion when full modalities are available and falls back to self-fusion under missing conditions. Additionally, we design Residual Self-Paced Entropic Optimal Transport (RSPEOT) to align heterogeneous feature distributions from a transport perspective. Instead of relying on the fixed sparsity coefficient in standard entropic optimal transport (EOT), RSPEOT introduces a residual-driven self-paced update that prioritizes reliable matches and progressively refines harder ones. This design alleviates the additional optimization burden of standard EOT while preserving reliable semantic alignment. Comprehensive experiments under complete and missing-modality protocols show consistent performance across arbitrary modality configurations. Code will be released upon publication.

Vision-language models (VLMs) have achieved remarkable performance by leveraging complementary information from large-scale image-text pairs. However, missing-modality inputs are commonly encountered during real-world deployment, often leading to significant performance degradation. Existing methods primarily enhance model robustness by learning modality compensation strategies from source training data. However, their reliance on source training data makes them difficult to apply when original data are unavailable due to privacy, storage, or accessibility constraints, such as clinical applications and personalized AI services. This raises an important yet underexplored question: can VLMs be efficiently adapted at test time for visual recognition with missing modalities without accessing source training data? To this end, we propose Test-Time Logit Prompting (TLP), a lightweight source-free test-time adaptation framework for visual recognition with missing modalities. To address missing-induced prediction shifts, TLP optimizes logit prompts with uncertainty-aware adjustment and modality-complete consistency regularization, adaptively adjusting prediction confidence while preserving semantic consistency. Extensive experiments across diverse vision-language benchmarks demonstrate that TLP consistently enhances recognition performance under missing-modality scenarios, achieving up to 8% improvements while requiring only hundreds of tunable parameters and a few test-time optimization steps.

Depression and anxiety in older adults with Mild Cognitive Impairment (MCI) are frequently underdiagnosed due to limited access to care. Multimodal analysis of remote clinical interviews is a scalable screening approach, but existing methods have three limitations. First, they do not correct temporal misalignment across multimodal features extracted at different resolutions, inducing spurious cross-modal associations. Second, remote recordings exhibit uneven modality dropout, but missing values are often zero-filled, making them indistinguishable from valid near-zero measurements. Finally, they do not jointly attribute predictions to modalities, questions, and interview moments, limiting fine-grained clinical interpretation. We propose a Temporally-Aligned, Missingness-Aware, Interpretable (TAMI) multimodal fusion framework. TAMI aligns speech, language, facial, and physiological features within question-answer segments on a shared timeline, encodes modality-level missingness over time, and conditions fusion on question context. In interviews with 49 older adults with MCI, TAMI achieved area under the receiver operating characteristic curve (AUROC) scores of 0.68 (depression) and 0.69 (anxiety). Fine-grained temporal alignment of multimodal features produced the largest performance gain ($Δ{\geq}0.1$). Multi-level interpretability analysis revealed that depression classification relied on eyegaze and open-ended questions, while anxiety classification depended on eyegaze and head pose, with attribution uniformly distributed across questions. Using only responses to the open-ended questions (5.1min), the depression model achieved an AUROC score of 0.67, which was not significantly different from using the full interview (19min) ($p>0.05$). Our findings support designing interview protocols centered on open-ended questions for depression screening in older adults with MCI.

Combining whole-body magnetic resonance imaging (WB-MRI) with clinical variables has the potential to improve systemic disease diagnosis by leveraging complementary sources of patient information. However, structured clinical variables are often incomplete or missing, limiting the applicability of conventional multimodal fusion methods that assume fixed inputs. In this work, we propose TACTIC (Tabular-Attribute Conditioned Transformer for Image Classification), a prompt-based multimodal framework that integrates WB-MRI and structured clinical data through conditional visual feature learning. By encoding clinical attributes as prompts, TACTIC supports an arbitrary number of tabular inputs and naturally handles missing data without requiring imputation or fixed input structures. We evaluate TACTIC on five WB-MRI classification tasks spanning systemic and oncologic applications, including diabetes, chronic obstructive pulmonary disease (COPD), breast cancer, prostate cancer, and metastasis diagnosis. Across all tasks, TACTIC consistently improves performance over image-only baselines when clinical information is available while maintaining strong predictive capability under incomplete tabular inputs. Our results demonstrate the effectiveness of prompt-based models as a flexible approach for improving WB-MRI analysis using clinical context. The model weights and code are available at https://github.com/lauradaza/TACTIC

Multimodal Emotion Recognition (MER) systems often suffer from missing modalities in real-world scenarios. Existing methods usually generate, align, or distill missing modalities as a whole, overlooking the heterogeneous nature of the information carried by each modality. Such holistic treatment mixes inferable shared semantics with uncertain modality-specific details, yielding unstable representations and degrading robustness. To address this issue, we propose the Primitive Memory Distillation (PriMD) framework. Unlike existing methods, PriMD takes an intra-modal perspective and focuses on how different types of information within a modality differ in recoverability within each modality. PriMD first disentangles cross-modal shared semantics from modality-specific representations, and then discretizes the latter into learnable semantic primitives to construct modality-specific memory banks. When modalities are missing, PriMD is a teacher-student framework that the student model uses the shared semantics of available modalities as queries to dynamically retrieve primitives. It compensates for missing modality-specific information within a constrained memory space and aligns with the teacher model. Extensive experiments on IEMOCAP, CMU-MOSI, and CMU-MOSEI demonstrate that PriMD achieves state-of-the-art performance and consistently stronger robustness across a wide range of missing-modality settings, while mitigating the instability caused by holistic feature inference. Our code and project website are available at https://github.com/JiaqiZhang-Sengoku/PriMD and https://jiaqizhang-sengoku.github.io/PriMD/, respectively.

Multi-modal sequential recommenders assume every item carries every modality, but real product catalogs often miss images or text, and a model trained on complete data loses much of its recommendation accuracy when a modality is unavailable at serving time. We propose Sequential Modality Dropout (SMD): during training, each modality stream (image and text) is independently erased with probability p for an entire user interaction history, so the model learns to predict the next item without relying on any single modality. We measure robustness by retention, the fraction of a model's full-modality accuracy (HR@10) that survives when a modality is removed at test time. Across four backbones (MM-SASRec, IISAN, MISSRec, and fMRLRec) on four Amazon domains, SMD raises text retention by 1.0 to 3.2x at essentially no cost to full-modality accuracy; under an extreme 95% per-item missing rate, it retains 61% of HR@10 versus 22% without (a 2.8x improvement). An optional cross-modal reconstruction loss further lifts retention from 90% to 98% on a simple additive backbone under severe text missingness. SMD is a four-line, architecture-agnostic change that makes multi-modal sequential recommenders robust to the missing modalities they actually encounter in deployment.

Multimodal federated learning (FL) supports collaborative modeling in privacy-sensitive health-sensing and medical settings, but realistic deployments often exhibit dual-axis modality missingness: clients have different modality sets, and individual samples may contain only subsets of the modalities available locally. Existing methods typically address these two axes separately. We propose Flux, a multimodal federated learning framework built around two complementary components. First, modality-aware confidence tempering learns sample-specific confidence for each modality through mask-aware unimodal supervision and fuses the confidence estimates from observed modalities into a sample-adaptive temperature that adjusts predictive sharpness according to evidence quality and completeness. Second, gradient-decoupled private adaptation applies this temperature only to a client-private prediction pathway, while training the shared federated model with a standard, untempered objective. This enables sample-specific, client-local confidence adaptation without allowing confidence-dependent gradients to perturb shared representation learning. Across four multimodal datasets, Flux achieves the highest average macro-F1 on every dataset, outperforming the strongest dataset-specific baseline by 0.8~2.2 points and by 1.6 points on average. Additional analyses demonstrate favorable calibration, temperature sensitivity to both modality missingness and input corruption, and more stable shared optimization under private-only tempering. Our code is available at https://github.com/AdibaOrz/Flux.

Multimodal fusion architectures typically assume all modalities are available at inference, yet sensor failures, acquisition variability, and cost constraints routinely produce incomplete observations. Existing work treats modality absence as a prediction-accuracy problem, leaving a more basic question unanswered: whether a model's confidence estimates remain calibrated when an entire input stream is removed. We argue that missing-modality robustness and calibrated uncertainty are a single coupled property, and introduce Modality-Conditioned Conformal Fusion (MCCF), an architecture that addresses both at once. MCCF combines a multimodal bottleneck fusion backbone trained with modality dropout, per-modality evidential heads producing modality-decomposed Dirichlet distributions, and a Dempster-Shafer combination rule that fuses the per-modality evidence into a joint predictive distribution; an absent modality contributes vacuous evidence that is structurally ignored, so the fused uncertainty automatically reflects the reduced information without test-time imputation. A Mondrian conformal calibration module keyed on the modality-presence mask then provides finite-sample group-conditional coverage for every non-empty modality subset. MCCF is, to our knowledge, the first method with formal coverage guarantees under arbitrary modality availability through architectural integration rather than post-hoc recalibration, and the evidential decomposition yields per-modality vacuity scores that localise uncertainty to the absent modality responsible. Across a synthetic problem and three real multimodal benchmarks, MCCF holds its target coverage on every modality-presence subset, substantially narrows the coverage gap between full and partial modalities relative to a marginal split-conformal baseline, and imposes no measurable accuracy cost relative to temperature-scaled and evidential baselines.

Visual object tracking aims to continuously locate specific targets within sequential frames, evolving from single-modal methods to multi-modal ones. However, existing multi-modal trackers are typically designed for fixed modality combinations, requiring separate models for different inputs. This leads to a poor adaptability to missing or imperfect modalities, and limited generalization. To address these issues, we propose a novel unified framework called AnyTrack for object tracking with any modalities. Specifically, we design a Modality-aware Interaction Module (MIM) to facilitate dynamic interaction across diverse modalities. This module bridges modality discrepancies and aggregates temporal cues to maintain spatio-temporal consistency during cross-modal interaction. Furthermore, we introduce a Context Understanding Module (CUM) to establish spatial correspondence between visual features and target locations via global-local prompts. This module employs target-aware context modeling to enhance foreground-background discrimination for precise localization. Finally, to support the training and evaluation under diverse modalities, we extend existing multi-modal object tracking benchmarks by incorporating grayscale images, language descriptions, and audio clips. Extensive experiments with both complete and missing modality settings demonstrate that our AnyTrack achieves state-of-the-art performance, validating its effectiveness and flexibility. The source code is available at https://github.com/IdolLab/AnyTrack.

Most existing multimodal sentiment analysis approaches assume access to complete multimodal inputs. However, real-world applications frequently encounter incomplete or corrupted modalities, posing a critical challenge. Although several methods have been proposed to tackle this issue, they mainly rely on data imputation and heuristic coordination constraints, which fail to effectively extract and leverage task-relevant information from the incomplete multimodal data. To address this challenge, we propose a unified framework termed Mutual Information Disentanglement with uncertainty-Aware fuSion (MIDAS), which effectively restructures multimodal representations under incomplete conditions. MIDAS adopts a variational modeling strategy to represent each modality with multivariate Gaussian latent variables and further decomposes them into shared and exclusive factors. To obtain reliable representations, we design a minimax objective that minimizes the mutual information between shared and exclusive spaces for stable disentanglement, while maximizing the mutual information among shared spaces across modalities to enhance semantic alignment. In addition, an uncertainty-aware fusion mechanism is introduced, where posterior variance is leveraged as a reliability indicator to adaptively weight latent features during fusion, ensuring robust integration even when modalities are incomplete. Extensive experiments on three widely used datasets show that MIDAS achieves strong and consistent performance gains over competitive baselines across a wide range of incomplete settings, demonstrating its effectiveness and robustness for incomplete data scenarios.

Multimodal classification typically assumes all modalities are available, yet real-world inputs are often incomplete. Imputation and dynamic fusion can mitigate such incompleteness, but existing methods operate at a coarse modality level and thus cannot retain reliable components while suppressing misleading ones within the same recovered modality, compromising prediction reliability. To address this issue, we propose GAUGE, a lightweight counterfactual gating framework for incomplete multimodal classification. GAUGE first imputes missing modalities with a frozen imputer and encodes observed and recovered inputs uniformly as fine-grained evidence units. Rather than intervening on each unit explicitly, GAUGE scores the counterfactual effect of replacing every unit with a reference representation through prediction-aware Taylor evidence scores, all obtained in a single forward-backward pass. These scores are mapped to continuous gates, which are converted into additive attention-logit biases for unit-wise evidence modulation without altering the backbone architecture. Experiments across six benchmarks demonstrate that GAUGE outperforms strong baselines across diverse incomplete-input settings. Furthermore, a Taylor remainder theoretical analysis characterizes the error of the first-order approximation relative to the exact counterfactual effect, establishing GAUGE as a principled and scalable framework for fine-grained evidence control under modality incompleteness.

Multimodal Sentiment Analysis (MSA) integrates text, audio, and vision to infer human affect, yet real-world multimodal observations are often incomplete. Existing methods for incomplete-observation MSA mainly follow two paradigms. Reconstruction-based methods recover missing information from observed modalities, while joint-representation methods learn directly from incomplete inputs. Although effective, these methods usually treat modality reliability only implicitly within representation learning or fusion design rather than modeling it explicitly. We argue that modality reliability is a central variable in incomplete-observation settings. Failure to model it explicitly gives rise to two related issues. The first is reliability mismatch, in which the affective evidence retained by each modality varies across samples and missing rates. The second is reliability propagation bias, in which messages from degraded modalities may adversely affect cross-modal interaction and predictive performance. To address these issues, we propose MRCF, a Modality Reliability-Calibrated Framework for MSA with incomplete observations. MRCF contains a Reliability-Aware Branch that estimates sample-specific modality reliability from intramodal quality cues and cross-modal semantic consistency, a Reliability-Guided Interaction Branch that uses the estimated scores to modulate cross-modal information flow, and a Reliability-Calibrated Fusion Module that integrates reliability and semantic cues for final prediction. Experiments on CMU-MOSI, CMU-MOSEI, and CH-SIMS show that MRCF achieves strong performance under standard incomplete-observation protocols. Further analyses provide evidence that explicit reliability modeling helps mitigate reliability mismatch and reliability propagation bias during interaction and fusion.

In multimodal crack segmentation for industrial facilities, the key challenge is preventing missing modalities from degrading pixel-level performance while maintaining low computational cost. Existing methods struggle to address semantic degradation caused by missing modalities. We propose Compass, a lightweight network for robust crack segmentation under arbitrary missing modalities. Compass comprises Degradation Simulation Distillation (DSD), Needle Block, and Evidential Topology-Preserving Fusion (ETPF). DSD constructs a degradation simulation stream that mimics more severe missing conditions and performs reciprocal distillation with the original stream, decoupling complete perception from degradation adaptation. Within DSD, Feature-Aware Prototype Transmitter (FAPT) performs modality agnostic prototype-guided feature completion to maintain semantic integrity under incomplete modality conditions. As a lightweight backbone, Needle injects crack-direction cues into WKV modulation and combines connectivity-aware gating with anisotropic context probing for structure-aware modeling. ETPF fuses multimodal features via Dempster-Shafer evidential combination with uncertainty-gated decoding, preserving crack topology while suppressing unreliable features. Experiments on three datasets demonstrate state-of-the-art (SOTA) performance under diverse missing modality scenarios. Even with 90% depth modality missing on CrackDepth, Compass achieves F1 of 0.8216 and mIoU of 0.8434 with only 2.58M parameters. The code is available at https://github.com/Karl1109/Compass.