Overview

Multimodal fusion studies how to combine inputs such as images, text, audio, medical scans, sensor streams, and structured records so models can use their complementary information. Common approaches include early or late fusion, cross-attention and contrastive alignment, and adaptive gates or mixtures of experts that weight modalities by task, sample, or estimated reliability. Methods are tested across settings such as BraTS medical segmentation, CMU-MOSI and CMU-MOSEI sentiment analysis, RGB-thermal detection, and clinical prediction, with growing attention to missing, noisy, or misaligned inputs. A central open tension is that additional modalities can help when they add useful evidence, but can also introduce noise or let a dominant modality suppress weaker ones; robust gains and generalization beyond benchmark conditions remain difficult to establish.

Latest papers

772 papers73 papers in the last four weeks, down 12% on the four weeks before. 0.4% of all new papers.

May 6, 2026

Gated Multimodal Learning for Interpretable Property Energy Performance Prediction and Retrofit Scenario Analysis

Achieving resilient and sustainable cities requires scalable approaches to decarbonising residential buildings, which account for about 20% of UK greenhouse gas emissions and 25% of energy-related emissions in the European Union. Energy Performance Certificates (EPCs) support regulation and retrofit planning, but their reliance on on-site inspections limits timely city-scale assessment. This study introduces a gated multimodal model to predict Standard Assessment Procedure (SAP) energy efficiency and Environmental Impact (EI) scores by integrating EPC tabular variables, assessor-written free text, and Geographic Information System (GIS)-derived spatial features describing footprint geometry, height, area, and orientation. Sample-wise gating learns property-specific modality weights, while an auxiliary band classification head stabilises training. In a Westminster, London case study, the model predicts SAP and EI scores with MAEs of 4.03 and 4.76 points and R2 values of 0.757 and 0.748, respectively, achieving a mean MAE of 4.39. Ablation results show that full multimodal fusion outperforms unimodal and bimodal baselines for both score prediction and band-level classification. Interpretability analyses provide decision-relevant evidence: gating weights indicate strong reliance on assessor text; SHAP highlights main fuel, built form, and construction age band; text occlusion prioritises roof and wall fields; and spatial attribution is dominated by height and footprint area, with sensitivity to footprint shape. The validated framework is further applied to retrofit scenarios for wall insulation, roof insulation, and window glazing upgrades, indicating projected improvements in SAP, EI, annual energy cost, and equivalent CO2 emissions. Overall, the framework provides scalable property-level evidence for retrofit screening, intervention prioritisation, and net-zero housing transitions.
May 6, 2026

To Fuse or to Drop? Dual-Path Learning for Resolving Modality Conflicts in Multimodal Emotion Recognition

Multimodal emotion recognition (MER) benefits from combining text, audio, and vision, yet standard fusion often fails when modalities conflict. Crucially, conflicts differ in resolvability: benign conflicts stem from missing, weak, or ambiguous cues and can be mitigated by cross-modal calibration, while severe conflicts arise from intrinsically contradictory (e.g., sarcasm) or misleading signals, for which forced fusion may amplify errors. Recognizing this, we propose Dual-Path Conflict Resolution (DCR), a unified framework that learns when to fuse and when to drop modalities. Path I (Affective Fusion Distiller, AFD) performs reverse distillation from audio/visual teachers to a textual student using temporally weighted class evidence, thereby enhancing representation-level calibration and improving fusion when alignment is beneficial. Path II (Affective Discernment Agent, ADA) formulates MER as a contextual bandit that selects among fusion and unimodal predictions based on a dual-view state and a calibration-aware reward, enabling decision-level arbitration under irreconcilable conflicts without requiring per-modality reliability labels. By taking into account the full multimodal context and coupling soft calibration with hard arbitration, DCR reconciles conflicts that can be aligned while bypassing misleading modalities when fusion is harmful. Across five benchmarks covering both dialogue-level and clip-level MER, DCR consistently outperforms competitive baselines or achieves highly competitive results. Further ablations, conflict-specific subset evaluation, and modality-selection analysis verify that AFD and ADA are complementary and jointly improve robust conflict-aware emotion recognition.
May 6, 2026

Hybrid Congestion Classification Framework Using Flow-Guided Attention and Empirical Mode Decomposition

Accurate traffic congestion classification requires models that jointly capture roadway scene context and non-stationary traffic motion, yet most prior work treats these requirements in isolation. Vision-based methods often depend on appearance cues with standard temporal pooling, which can bias predictions toward static infrastructure, whereas signal-based approaches characterize temporal dynamics but lack the spatial context needed for scene-level localization. These complementary limitations motivate a unified framework that links motion evidence to spatial feature selection while preserving data-adaptive temporal characterization. This study therefore proposes FLO-EMD, a hybrid approach that couples motion-guided attention with empirical, data-driven temporal decomposition. Dense optical flow guides channel and spatial attention so that RGB features are refined toward motion-relevant regions. In parallel, aggregated flow statistics form compact motion traces that are decomposed using Empirical Mode Decomposition (EMD) to extract intrinsic temporal components. The resulting EMD embedding is fused with learned spatiotemporal representations to classify light, medium, and heavy congestion. Experiments on 1,050 five-second clips from four surveillance networks show that FLO-EMD achieves 97.5% overall test accuracy (weighted F1 = 0.9742), outperforming established baselines and remaining robust across diverse environmental conditions; ablation and sensitivity analyses further quantify the contributions of EMD, the number of intrinsic mode functions, and the selected motion descriptors.
May 5, 2026

LUCAS-MEGA: A Large-Scale Multimodal Dataset for Representation Learning in Soil-Environment Systems

Understanding soil is fundamental to agriculture, carbon cycling, and environmental sustainability, yet progress is limited by fragmented and heterogeneous datasets that constrain modeling to small-scale predictive settings rather than high-dimensional representation learning. We introduce LUCAS-MEGA, a large-scale multimodal dataset constructed through systematic data fusion of European soil-environment observations, with the LUCAS survey as its backbone. The fused dataset comprises over 70,000 samples and more than 1,000 features spanning physical, chemical, environmental, biological, and visual attributes, aggregated from 68 source datasets. To enable integration at scale, we develop SoilFuser, a multi-agent, human-in-the-loop data fusion pipeline that standardizes heterogeneous data formats and measurement protocols, resolves inconsistencies and invalid entries (e.g., unit inconsistencies, codebook mismatches, and erroneous values), incorporates natural language annotations, and harmonizes multimodal attributes and metadata into a unified, machine learning-ready feature space. The resulting dataset captures key characteristics of real-world soil observations, including multimodality, uneven feature coverage, and heterogeneous uncertainty. To demonstrate the usability of LUCAS-MEGA for data-driven modeling, we pretrain a multimodal tabular transformer (SoilFormer) using a self-supervised objective based on feature masking, achieving stable training, strong predictive performance, and representations that support uncertainty-aware prediction. We further show that the learned representations recover relationships consistent with established soil processes. LUCAS-MEGA is released with open access and is accompanied by composable, agent-friendly APIs that support structured querying and data-driven workflows.
May 5, 2026

Multimodal Learning on Low-Quality Data with Conformal Predictive Self-Calibration

Multimodal learning often grapples with the challenge of low-quality data, which predominantly manifests as two facets: modality imbalance and noisy corruption. While these issues are often studied in isolation, we argue that they share a common root in the predictive uncertainty towards the reliability of individual modalities and instances during learning. In this paper, we propose a unified framework, termed Conformal Predictive Self-Calibration (CPSC), which leverages conformal prediction to equip the model with the ability to perform self-guided calibration on-the-fly. The core of our proposed CPSC lies in a novel self-calibrating training loop that seamlessly integrates two key modules: (1) Representation Self-Calibration, which decomposes unimodal features into components, and selectively fuses the most robust ones identified by a conformal predictor to enhance feature resilience. (2) Gradient Self-Calibration, which recalibrates the gradient flow during backpropagation based on instance-wise reliability scores, steering the optimization towards more trustworthy directions. Furthermore, we also devise a self-update strategy for the conformal predictor to ensure the entire system co-evolves consistently throughout the training process. Extensive experiments on six benchmark datasets under both imbalanced and noisy settings demonstrate that our CPSC framework consistently outperforms existing state-of-the-art methods. Our code is available at https://github.com/XunCHN/CPSC.
May 5, 2026

Unified Multimodal Visual Tracking with Dual Mixture-of-Experts

Multimodal visual object tracking can be divided into to several kinds of tasks (e.g. RGB and RGB+X tracking), based on the input modality. Existing methods often train separate models for each modality or rely on pretrained models to adapt to new modalities, which limits efficiency, scalability, and usability. Thus, we introduce OneTrackerV2, a unified multi-modal tracking framework that enables end-to-end training for any modality. We propose Meta Merger to embed multi-modal information into a unified space, allowing flexible modality fusion and robustness. We further introduce Dual Mixture-of-Experts (DMoE): T-MoE models spatio-temporal relations for tracking, while M-MoE embeds multi-modal knowledge, disentangling cross-modal dependencies and reducing feature conflicts. With a shared architecture, unified parameters, and a single end-to-end training, OneTrackerV2 achieves state-of-the-art performance across five RGB and RGB+X tracking tasks and 12 benchmarks, while maintaining high inference efficiency. Notably, even after model compression, OneTrackerV2 retains strong performance. Moreover, OneTrackerV2 demonstrates remarkable robustness under modality-missing scenarios.
May 5, 2026

Disentangling Shared and Task-Specific Representations from Multi-Modal Clinical Data

Real-world clinical data is inherently multimodal, providing complementary evidence that mirrors the practical necessity of jointly assessing multiple related outcomes. Although multi-task learning can improve efficiency by sharing information across outcomes, existing approaches often fail to balance shared representation learning with outcome-specific modeling. Hard parameter sharing can trigger negative transfer when task gradients conflict, while flexible sharing may still entangle shared and task-specific signals. To address this, we propose a multi-task framework built on a unified Transformer for multimodal fusion, augmented with Orthogonal Task Decomposition (OrthTD) to split patient representations into shared and task-specific subspaces and impose a geometric orthogonality constraint to reduce redundancy and isolate task-specific signals. We evaluated OrthTD on a real-world cohort of 12,430 surgical patients for predicting four outcomes. OrthTD achieved average AUC (area under the receiver operating characteristic curve) of 87.5% and average AUPRC (area under the precision-recall curve) of 37.2%, consistently outperformed advanced tabular and multi-task methods. Notably, OrthTD achieves substantial gains in AUPRC, indicating superior performance in identifying rare events within imbalanced clinical data. These results suggest that enforcing non-redundant shared and task-specific representations can improve multi-outcome prediction from multimodal clinical data.
May 4, 2026

OphMAE: Bridging Volumetric and Planar Imaging with a Foundation Model for Adaptive Ophthalmological Diagnosis

The advent of foundation models has heralded a new era in medical artificial intelligence (AI), enabling the extraction of generalizable representations from large-scale unlabeled datasets. However, current ophthalmic AI paradigms are predominantly constrained to single-modality inference, thereby creating a dissonance with clinical practice where diagnosis relies on the synthesis of complementary imaging modalities. Furthermore, the deployment of high-performance AI in resource-limited settings is frequently impeded by the unavailability of advanced three-dimensional imaging hardware. Here, we present the Ophthalmic multimodal Masked Autoencoder (OphMAE), a multi-imaging foundation model engineered to synergize the volumetric depth of 3D Optical Coherence Tomography (OCT) with the planar context of 2D en face OCT. By implementing a novel cross-modal fusion architecture and a unique adaptive inference mechanism, OphMAE was pre-trained on a massive dataset with of 183,875 paired OCT images derived from 32,765 patients. In a rigorous benchmark encompassing 17 diverse diagnostic tasks with 48,340 paired OCT images from 8,191 patients, the model demonstrated state-of-the-art performance, achieving an Area Under the Curve (AUC) of 96.9% for Age-related Macular Degeneration (AMD) and 97.2% for Diabetic Macular Edema (DME), consistently surpassing existing single-modal and multimodal foundation models. Crucially, OphMAE exhibits robust engineering adaptability: it maintains high diagnostic accuracy, such as 93.7% AUC for AMD, even when restricted to single-modality 2D inputs, and demonstrates exceptional data efficiency by retaining 95.7% AUC with as few as 500 labeled samples. This work establishes a scalable and adaptable framework for ophthalmic AI, ensuring robust performance across different tasks.
May 4, 2026

PC-MNet: Dual-Level Congruity Modeling for Multimodal Sarcasm Detection via Polarity-Modulated Attention

Multimodal sarcasm detection, which aims to precisely identify pragmatic incongruities between literal text and nonverbal cues, has gained substantial attention in multimodal understanding. Recent advancements have predominantly relied on naïve similarity-based attention mechanisms and uniform late fusion strategies.Furthermore, given that functional entanglement restricts traditional late fusions, we incorporate a scalar congruity routing mechanism and a prior-guided contextual graph. This mechanism anchors a generalized incongruity manifold through a two-stage asymmetric optimization driven by inconsistency-aware contrastive learning, selectively fusing only the most discriminative multi-granularity evidence. Extensive experiments on the MUStARD benchmark and its spurious-correlation-mitigated balanced datasets demonstrate that our approach achieves new state-of-the-art performance, surpassing the strongest multimodal baseline by a substantial 3.14% improvement in Macro-F1. By architecturally isolating atomic, composition, and contextual conflicts. This work provides a robust, decoupled paradigm for modeling subtle pragmatic incongruities in human communication.
May 4, 2026

MultiSense-Pneumo: A Multimodal Learning Framework for Pneumonia Screening in Resource-Constrained Settings

Pneumonia remains a leading global cause of morbidity and mortality, particularly in low-resource settings where access to imaging, laboratory testing, and specialist care is limited. Clinical assessment relies on heterogeneous evidence, including symptoms, respiratory patterns, spoken descriptions, and chest imaging, making frontline screening inherently multimodal. However, many existing computational approaches remain unimodal and focus primarily on radiographs. In this work, we present MultiSense-Pneumo, a multimodal research prototype for pneumonia-oriented screening and triage support that integrates structured symptom descriptors, cough audio, spoken language, and chest radiographs. The system combines deterministic symptom triage, LightGBM-based acoustic classification, domain-adversarial radiograph analysis using ResNet-18, transformer-based speech recognition, and an interpretable late-fusion operator. Each modality is transformed into a normalized concern signal and aggregated into a unified screening estimate. The fusion weights are hand-specified and are treated as heuristic, interpretable parameters rather than learned or clinically optimized values. MultiSense-Pneumo is implemented with offline execution in mind on standard laptop-class hardware, but it is not presented as a deployment-validated or clinically validated diagnostic system. Experimental results demonstrate strong component-level performance of the radiograph pathway under synthetic domain shifts, while also highlighting important limitations, especially reduced abnormal-class recall for cough acoustics and the absence of paired end-to-end multimodal patient evaluation. MultiSense-Pneumo is therefore intended as a framework and component-level prototype for screening and triage research.
May 4, 2026

FLoRA: Fusion-Latent for Optical Reconstruction and Flood Area Segmentation via Cross-Modal Multi-Task Distillation Network

Accurate flood water mapping is critical for disaster management, yet current methods struggle to fully exploit the potential of spaceborne imagery. Optical data offers high interpretability but is limited by environmental conditions, whereas SAR provides reliable all-weather coverage with reduced visual interpretability. FLoRA (Fusion Latent for Optical Reconstruction and Area Segmentation) is a cross-modal multi-task framework that jointly reconstructs high-fidelity optical imagery and segments flood water regions from Sentinel 1 SAR by fusing the complementary strengths of optical and SAR data. During training, a lightweight optical teacher (driven by RGB and NDVI priors) provides pyramidal features that guide SAR representations into a fusion latent space via multiscale windowed cross attention and FiLM conditioning, with gated residuals preventing overcorrection. This design enables multi-task learning across two complementary objectives: (a) SAR-to-optical translation for fine-grained RGB reconstruction and (b) flood water region segmentation for hydrologic interpretation. The dual decoders are optimized using Charbonnier SSIM for structural fidelity, edge FFT magnitude losses for spectral realism, and Dice BCE hydrology-aware edge alignment for precise flood water delineation. A feature distillation constraint further aligns fused SAR features with the optical teacher's manifold. Evaluations on SEN1FLOODS11, DEEPFLOOD, and SEN12MS demonstrate that FLoRA surpasses fusion baselines in PSNR, SSIM, and LPIPS, demonstrating that multi-modal fusion within a teacher-guided latent space yields semantically faithful and physically consistent flood-water intelligence from spaceborne observations.
May 3, 2026

MER-DG: Modality-Entropy Regularization for Multimodal Domain Generalization

Deploying multimodal models in real-world scenarios requires generalization to new environments where recording conditions differ from training, a challenge known as multimodal domain generalization (MMDG). Standard architectures employ separate encoders for each modality and a fusion module, training the system end-to-end by optimizing on the fused features. In this paper, we identify that such joint optimization causes encoders to exploit cross-modal co-occurrences, statistical relationships between modalities that arise from source-specific recording conditions, rather than learning domain-invariant features. We term this failure mode Fusion Overfitting. To address this, we propose Modality-Entropy Regularization for Domain Generalization (MER-DG), which maximizes the entropy of each encoder's feature distribution to preserve feature diversity. MER-DG is architecture-agnostic and integrates into existing multimodal frameworks as an additive loss term. Extensive experiments on EPIC-Kitchens and HAC benchmarks demonstrate average improvements of approximately 5% over standard fusion and approximately 2% over state-of-the-art methods.
May 3, 2026

EAPFusion: Intrinsic Evolving Auxiliary Prior Guidance for Infrared and Visible Image Fusion

Infrared-visible image fusion aims to create an information-rich fused image by integrating the complementary thermal saliency from infrared sensing and fine textures from visible imaging. Such accurate fusion is essential for real-world perception applications in complex scenes, including nighttime autonomous driving, search and rescue, and surveillance, and can further benefit downstream tasks such as semantic segmentation. However, most existing fusion methods rely upon static trained weights that cannot adapt to scene-specific content at inference time, and often suffer from a granularity mismatch when coarse auxiliary semantics are injected, which makes it difficult to simultaneously highlight targets and preserve details. In this work, we propose EAPFusion to address these issues by using self-evolving intrinsic priors instead of relying on external auxiliary models. Concretely, EAPFusion maintains a compact set of intrinsic priors and progressively updates them across scales. These evolved priors are utilized to dynamically generate convolutional kernels, shifting the paradigm from fixed, pre-trained filters to instance-adaptive parameters via prior-conditioned dynamic convolution. Furthermore, we design a channel-level fusion module that shuffles and interleaves infrared and visible channels, applying local channel mixing to boost cross-modal complementarity. Experiments on different datasets, including cross-dataset evaluation and semantic segmentation, show that the proposed method achieves state-of-the-art quantitative and qualitative fusion results, and consistently boosts downstream performance. Code is coming soon.
May 3, 2026

Query-Dependent Use of Generated Descriptions for Reliable Visual Question Answering

Vision-Language Models (VLMs) hallucinate objects that are not present, and a growing line of work tries to curb this by feeding the model its own generated caption as auxiliary evidence -- assuming that a caption, once available, is something to consume. We show this fails: naively appending a caption can lower accuracy rather than raise it, dropping Qwen2.5-VL-3B† on HallusionBench by nearly ten points. To understand why, we build GD-Probe, a diagnostic set that pairs a global and a detail question on the same image, so that any difference in caption effect is attributable to the question alone. Caption utility proves to be a per-query property: the same caption helps global questions and harms detail ones, through a single mechanism -- an embedded caption competes with the image for attention and pulls the model's evidence onto its own text -- whose sign is set by whether the caption covers the queried content. Crucially, this regime is readable from quantities the decoder already emits, with no attention access or grounding. We turn this into GEASS (Gated Evidence-Adaptive Selective Caption Trust), a training-free, logit-level module that decides per query how much of the caption to trust, gating it by the clean path's confidence, weighting it by the entropy reduction it induces, and raising the evidence bar when the two pathways disagree. Across four VLMs and two benchmarks (POPE and HallusionBench), GEASS improves over both vanilla inference and contrastive decoding under a single fixed setting, adding only two forward passes and no parameters.
May 3, 2026

Delayed Commitment for Representation Readiness in Stage-wise Audio-Visual Learning

Stage-wise audio-visual encoders propagate fused intermediate states across layers, making the formation of later representations depend on the readiness of earlier fusion states. Strong local audio-visual agreement provides useful correspondence evidence, yet a fused state also needs sufficient cross-layer and cross-modal support before it can reliably guide later fusion. This paper studies this issue through propagation-aware representation readiness and formulates premature perceptual commitment as a readiness-deficiency problem, where local plausibility, propagation influence, and support insufficiency jointly appear at an intermediate stage. We propose the Delayed Perceptual Commitment Network (DPC-Net), an encoder-level framework that estimates an observable readiness-deficiency surrogate, localizes the intervention-sensitive bottleneck, and applies support-aware correction with cross-layer and cross-modal evidence. DPC-Net preserves task-specific heads, losses, decoding modules, and evaluation protocols, making it applicable to different audio-visual tasks through encoder-side intervention. Experiments on audio-visual speech separation, audio-visual event localization, and audio-visual speech recognition show consistent improvements across reconstruction, localization, and recognition regimes. Further analyses on component contribution, selection criteria, counterfactual intervention, and readiness trajectories support the effectiveness of readiness-guided bottleneck correction.
May 2, 2026

Towards Visual Query Localization in the 3D World

Visual query localization (VQL) aims to predict the spatio-temporal response of the most recent occurrence in a sequence given a query. Currently, most research focuses on visual query localization in 2D videos, while its counterpart in 3D space has received little attention. In this paper, we make the first attempt to address visual query localization in the 3D world by introducing a novel benchmark, dubbed 3DVQL. Specifically, 3DVQL contains 2,002 sequences with around 170,000 frames and 6.4K response track segments from 38 object categories. Each sequence in 3DVQL is provided with multiple modalities, including point clouds, RGB images, and depth images, to support flexible research. To ensure high-quality annotations, each sequence is manually annotated with multiple rounds of verification and refinement. To the best of our knowledge, 3DVQL is the first benchmark for 3D multimodal visual query localization. To facilitate comparison in subsequent research, we implement a series of representative 3D multimodal VQL baselines using point clouds and RGB images. The experimental results show that existing methods exhibit significant performance variations across different fusion modules. To encourage future research, we propose a lift-and-attention fusion algorithm named LaF, which significantly outperforms existing baseline models. Our benchmark and model will be publicly released at https://github.com/wuhengliangliang/3DVQL.
May 2, 2026

Research on Vision-Language Question Answering Models for Industrial Robots

A hierarchical cross-modal fusion model is proposed for vision-language question answering (VLQA) in industrial robotics, targeting the challenges of semantic ambiguity, complex environmental layouts, and domain-specific terminology common in modern manufacturing. The framework integrates advanced object detection, multi-scale visual encoding, syntactic parsing, and task-aware semantic attention to unite vision and language signals into a joint reasoning space. Region-based deep networks extract visual features, weighted embeddings aggregate, and recurrent neural parsing encodes sentence structures. Through fine-grained semantic alignment driven by adaptive fusion and cross-attention mechanisms, the system can handle operational queries, instruction steps, and anomaly detection with higher reliability. Compared to the existing VLQA benchmarks, validation experiments conducted on the IVQA and RIF benchmarks indicate improvements in semantic alignment, Top-1 accuracy, and robustness to ambiguous or procedural task queries. Ablation studies further quantify the impact of each architectural module, confirming the necessity of multi-level feature integration and context-driven gating for dependable industrial deployment. The technical advancements reported here provide core methodologies to improve the interpretability and operational effectiveness of industrial robots faced with diverse human-robot interaction tasks.
May 2, 2026

SplAttN: Bridging 2D and 3D with Gaussian Soft Splatting and Attention for Point Cloud Completion

Although multi-modal learning has advanced point cloud completion, the theoretical mechanisms remain unclear. Recent works attribute success to the connection between modalities, yet we identify that standard hard projection severs this connection: projecting a sparse point cloud onto the image plane yields an extremely sparse support, which hinders visual prior propagation, a failure mode we term Cross-Modal Entropy Collapse. To address this practical limitation, we propose SplAttN, which replaces hard projection with Differentiable Gaussian Splatting to produce a dense, continuous image-plane representation. By reformulating projection as continuous density estimation, SplAttN avoids collapsed sparse support, facilitates gradient flow, and improves cross-modal connection learnability. Extensive experiments show that SplAttN achieves state-of-the-art performance on PCN and ShapeNet-55/34. Crucially, we utilize the real-world KITTI benchmark as a stress test for multi-modal reliance. Counter-factual evaluation reveals that while baselines degenerate into unimodal template retrievers insensitive to visual removal, SplAttN maintains a robust dependency on visual cues, validating that our method establishes an effective cross-modal connection. Code is available at https://github.com/zay002/SplAttN.
May 2, 2026

EFGPP: Exploratory framework for genotype-phenotype prediction

Predicting complex human traits from genetic data is challenging because different genetic, clinical, and molecular data sources often contain different parts of the signal. Here, we present EFGPP, a reproducible framework for generating, ranking, and combining multiple types of data for genotype-to-phenotype prediction. We applied EFGPP to migraine prediction using UK Biobank data from 733 individuals. The framework combined genotype-derived features, principal components, clinical and metabolomic covariates, and polygenic risk scores generated from migraine and depression GWAS using PLINK, PRSice-2, AnnoPred, and LDAK-GWAS. The best single data type achieved a test AUC of 0.644, while combining multiple data types improved performance to 0.688 using migraine-focused inputs and 0.663 using cross-trait depression-derived inputs. Genetic features alone did not outperform the covariates-only baseline, but genotype-derived features performed better than PRS alone, and depression-derived PRS showed useful predictive signal. Overall, EFGPP provides a practical proof-of-concept framework for prioritising and integrating heterogeneous genetic data sources for complex phenotype prediction.
May 2, 2026

Multimodal Confidence Modeling in Audio-Visual Quality Assessment

Audio-visual quality assessment (AVQA) is essential for streaming, teleconferencing, and immersive media. In realistic streaming scenarios, distortions are often asymmetric, where one modality may be severely degraded while the other remains clean. Still, most contemporary AVQA metrics treat audio and video as equally reliable, causing confidence-unaware fusion to emphasize unreliable signals. This paper proposes MCM-AVQA, a multimodal confidence-aware AVQA framework that explicitly estimates modality-specific confidence and injects it into a dedicated audio-visual mixer for cross-modal attention. The Audio-Visual Mixer utilizes frame-level, confidence-guided channel attention to gate fusion, modulating feature interaction between modalities so that high-confidence streams dominate while unreliable inputs are suppressed, preserving temporal degradation patterns. A multi-head visual confidence estimator turns frame-level artifact probabilities into temporally smoothed, clip-level visual confidence scores, while an audio confidence module derives confidence from speech-quality cues without requiring a clean reference. Experiments on multiple AVQA benchmarks show that MCM-AVQA, and specifically its confidence-guided Audio-Visual Mixer, improve correlation with human mean opinion scores and yield more interpretable behavior under real-world asymmetric audio-visual distortions.
May 1, 2026

Semantic Context-aware mOdality fUsion Transformer (SCOUT): A Context-Aware Multimodal Transformer for Concept-Grounded Pathology Report Generation

Whole-slide images (WSIs) present a fundamental challenge for computational pathology due to their extreme resolution, multi-scale heterogeneity, and the requirement for clinically reliable interpretation. Although recent pathology foundation models have enabled fluent report generation, they often lack clinical grounding, failing to accurately represent key diagnostic concepts and relationships observed by pathologists. This limitation arises from the difficulty of integrating heterogeneous visual evidence spanning fine-grained cellular patterns, slide-level tissue architecture, and high-level diagnostic concepts, while maintaining interpretability and clinical coherence. Here we present SCOUT: Semantic Context-aware mOdality fUsion Transformer, a context-aware concept-grounded multimodal framework for pathology report generation that enables progressive conditioning of image representations by global slide information and explicit diagnostic concepts. The method integrates local histological patterns, whole-slide context, and expert-curated semantic descriptors within a unified learning paradigm, allowing visual features to be dynamically refined throughout the encoding process. By combining depth-aware contextual modulation with adaptive multimodal fusion during text generation, the framework produces clinically coherent reports while preserving complementarity across representational scales. Using CONCH1.5 features, we evaluate SCOUT against WSI-Caption, HistGen, and BiGen on TCGA-BRCA, MICCAI REG, and HistAI. SCOUT achieves the best BLEU-1 to BLEU-4 and METEOR scores on all datasets, plus the best ROUGE-L on TCGA-BRCA and MICCAI REG. On TCGA-BRCA, it reaches 0.436/0.303/0.202/0.156 BLEU-1/2/3/4 and 0.204 METEOR; on REG 2025, it achieves 0.865/0.834/0.805/0.780 and 0.568. These results support progressive contextual conditioning for grounded pathology report generation.
May 1, 2026

LIMSSR: LLM-Driven Sequence-to-Score Reasoning under Training-Time Incomplete Multimodal Observations

Real-world multimodal learning is often hindered by missing modalities. While Incomplete Multimodal Learning (IML) has gained traction, existing methods typically rely on the unrealistic assumption of full-modal availability during training to provide reconstruction supervision or cross-modal priors. This paper tackles the more challenging setting of IML under training-time incomplete observations, which precludes reliance on a ``God's eye view'' of complete data. We propose LIMSSR (LLM-Driven Incomplete Multimodal Sequence-to-Score Reasoning), a framework that reformulates this challenge as a conditional sequence reasoning task. LIMSSR leverages the semantic reasoning capabilities of Large Language Models via Prompt-Guided Context-Aware Modality Imputation and Multidimensional Representation Fusion to infer latent semantics from available contexts without direct reconstruction. To mitigate hallucinations, we introduce a Mask-Aware Dual-Path Aggregation to dynamically calibrate inference uncertainty. Extensive experiments on three Action Quality Assessment datasets demonstrate that LIMSSR significantly outperforms state-of-the-art baselines without relying on complete training data, establishing a new paradigm for data-efficient multimodal learning. Code is available at https://github.com/XuHuangbiao/LIMSSR.
May 1, 2026

Group Cognition Learning: Making Everything Better Through Governed Two-Stage Agents Collaboration

Centralized multimodal learning commonly compresses language, acoustic, and visual signals into a single fused representation for prediction. While effective, this paradigm suffers from two limitations: modality dominance, where optimization gravitates towards the path of least resistance, ignoring weaker but informative modalities, and spurious modality coupling, where models overfit to incidental cross-modal correlations. To address these, we propose Group Cognition Learning (GCL), a governed collaboration paradigm that applies a two-stage protocol after modality-specific encoding. In Stage 1 (Selective Interaction), a Routing Agent proposes directed interaction routes, and an Auditing Agent assigns sample-wise gates to emphasize exchanges that yield positive marginal predictive gain while suppressing redundant coupling. In Stage 2 (Consensus Formation), a Public-Factor Agent maintains an explicit shared factor, and an Aggregation Agent produces the final prediction through contribution-aware weighting while keeping each modality representation as a specialization channel. Extensive experiments on CMU-MOSI, CMU-MOSEI, and MIntRec demonstrate that GCL mitigates dominance and coupling, establishing state-of-the-art results across both regression and classification benchmarks. Analysis experiments further demonstrate the effectiveness of the design.
Apr 30, 2026

Linguistically Informed Multimodal Fusion for Vietnamese Scene-Text Image Captioning: Dataset, Graph Framework, and Phonological Attention

Scene-text image captioning requires fusing three information streams -- visual features, OCR-detected text, and linguistic knowledge -- to generate descriptions that faithfully integrate text visible in images. Existing fusion approaches treat text as language-agnostic, which fails for Vietnamese: a tonal language where diacritics alter word meaning, OCR errors are pervasive, and word boundaries are ambiguous. We argue that Vietnamese scene-text captioning demands linguistically informed multimodal fusion, where language-specific structural knowledge is explicitly incorporated into the fusion mechanism. Motivated from these insights, we propose HSTFG (Heterogeneous Scene-Text Fusion Graph), a general-purpose graph fusion framework with learned spatial attention bias, and show through topology analysis that cross-modal graph edges are harmful for scene-text fusion. Building on this finding, we design PhonoSTFG (Phonological Scene-Text Fusion Graph) which specializes graph-level fusion for Vietnamese linguistic reasoning. To support evaluation, we introduce ViTextCaps, the first large-scale Vietnamese scene-text captioning dataset (15{,}729 images with 74{,}970 captions), with comprehensive linguistic analysis showing that 52.8% of the vocabulary is at risk of diacritic collision.
Apr 30, 2026

JI-ADF: Joint-Individual Learning with Adaptive Decision Fusion for Multimodal Skin Lesion Classification

Skin lesion classification is essential for early dermatological diagnosis, yet many existing computer-aided systems rely primarily on dermoscopic images and underutilize the multimodal evidence routinely available in clinical practice. To address this gap, we propose JI-ADF, a trimodal deep learning framework that integrates dermoscopic images, clinical photographs, and structured patient metadata for clinically grounded skin lesion classification. The proposed architecture combines joint multimodal representation learning with modality-specific auxiliary supervision and an adaptive decision fusion mechanism that dynamically calibrates modality contributions on a per-sample basis. To enhance cross-modal reasoning while preserving modality-specific evidence, we further introduce a multimodal fusion attention (MMFA) module. We evaluate JI-ADF on the large-scale MILK10k benchmark, which reflects real-world clinical acquisition conditions and severe class imbalance. The proposed method demonstrates strong and well-balanced performance across lesion categories, improving sensitivity and Dice score while maintaining high specificity and good calibration. Extensive analyses, including modality ablation, calibration evaluation, and Grad-CAM visualization, further confirm the robustness and clinically meaningful behavior of the model. These results indicate that JI-ADF provides a reliable and practical foundation for multimodal skin lesion classification in real-world clinical settings.
Apr 30, 2026

Representative Spectral Correlation Network for Multi-source Remote Sensing Image Classification

Hyperspectral image (HSI) and SAR/LiDAR data offer complementary spectral and structural information for land-cover classification. However, their effective fusion remains challenging due to two major limitations: The spectral redundancy in high-dimensional HSI and the heterogeneous characteristics between multi-source data. To this end, we propose Representative Spectral Correlation Network (RSCNet), a novel multi-source image classification framework specifically designed to address the above challenges through spectral selection and adaptive interaction. The network incorporates two key components: (1) Key Band Selection Module (KBSM) that adaptively selects task-relevant spectral bands from the original HSI under cross-source guidance, thereby alleviating redundancy and mitigating information loss from conventional PCA-based spectral reduction. Moreover, the learned band subset exhibits highly discriminative spectral structures that align with discriminative semantic cues, promoting compact yet expressive representations. (2) Cross-source Adaptive Fusion Module (CAFM) that performs cross-source attention weighting and local-global contextual refinement to enhance cross-source feature interaction. Experiments on three public benchmark datasets demonstrate that our RSCNet achieves superior performance compared with state-of-the-art methods, while maintaining substantially lower computational complexity. Our codes are publicly available at https://github.com/oucailab/RSCNet.
Apr 29, 2026

VTBench: A Multimodal Framework for Time-Series Classification with Chart-Based Representations

Time-series classification (TSC) has advanced significantly with deep learning, yet most models rely solely on raw numerical inputs, overlooking alternative representations. While texture-based encodings such as Gramian Angular Fields (GAF) and Recurrence Plots (RP) convert time series into 2D images, they often require heavy preprocessing and yield less intuitive representations. In contrast, chart-based visualizations offer more interpretable alternatives and show promise in specific domains; however, their effectiveness remains underexplored, with limited systematic evaluation across chart types, visual encoding choices, and datasets. In this work, we introduce VTBench, a systematic and extensible framework that re-examines TSC through multimodal fusion of raw sequences and chart-based visualizations. VTBench generates lightweight, human-interpretable plots -- line, area, bar, and scatter, providing complementary views of the same signal. We develop a modular architecture supporting multiple fusion strategies, including single-chart visual-numerical fusion, multi-chart visual fusion, and full multimodal fusion with raw inputs. Through experiments across 31 UCR datasets, we show that: (1) chart-only models are competitive in selected settings, particularly on smaller datasets; (2) combining multiple chart types can improve accuracy by capturing complementary visual cues; and (3) multimodal models improve or maintain performance when visual features provide non-redundant information, but may degrade accuracy when they introduce redundancy. We further distill practical guidelines for selecting chart types, fusion strategies, and configurations. VTBench establishes a unified foundation for interpretable and effective multimodal time-series classification.
Apr 29, 2026

A Multimodal Pre-trained Network for Integrated EEG-Video Seizure Detection

Reliable seizure detection in mouse models is essential for preclinical epilepsy research, yet manual review of synchronized video-EEG recordings is labor-intensive and single-modality systems fail for complementary reasons: video-based methods are easily confounded by benign behaviors, whereas EEG-based methods are vulnerable to ictal motion artifacts. We present EEGVFusion, a multimodal framework that combines self-supervised EEG representation learning, spatio-temporal video encoding, optimal-transport alignment, and bidirectional cross-attention to integrate neural and behavioral evidence. We also curate an expert-annotated dataset of synchronized EEG and video recordings comprising 93 sessions from 15 mice for training and evaluation. In the random-session split, EEGVFusion achieved a Balanced Accuracy of 0.9957 with perfect event sensitivity and an Event FAR of 0.6250 FP/h, indicating strong seizure detection performance with a low false-alarm burden. In a single held-out-subject evaluation with Subject 110 reserved for testing, EEGVFusion achieved a Balanced Accuracy of 0.9718 and reduced Event FAR from 2.7250 FP/h for the EEG-only counterpart to 0.4833 FP/h while preserving perfect event sensitivity. Targeted ablations further showed that EEG pre-training and OT alignment help reduce false alarms while preserving event sensitivity.
Apr 29, 2026

TimeMM: Time-as-Operator Spectral Filtering for Dynamic Multimodal Recommendation

Multimodal recommendation improves user modeling by integrating collaborative signals with heterogeneous item content. In real applications, user interests evolve over time and exhibit nonstationary dynamics, where different preference factors change at different rates. This challenge is amplified in multimodal settings because visual and textual cues can dominate decisions under different temporal regimes. Despite strong progress, most multimodal recommenders still rely on static interaction graphs or coarse temporal heuristics, which limits their ability to model continuous preference evolution with fine-grained temporal adaptation. To address these limitations, we propose TimeMM, a time-conditioned spectral filtering framework for dynamic multimodal recommendation. TimeMM instantiates Time-as-Operator by mapping interaction recency to a family of parametric temporal kernels that reweight edges on the user--item graph, producing component-specific representations without explicit eigendecomposition. To capture non-stationary interests, we introduce Adaptive Spectral Filtering that mixes the operator bank according to temporal context, yielding prediction-specific effective spectral responses. To account for modality-specific temporal sensitivity, we further propose Spectral-Aware Modality Routing that calibrates visual and textual contributions conditioned on the same temporal context. Finally, a ranking-space Spectral Diversity Regularization encourages complementary expert behaviors and prevents filter-bank collapse. Extensive experiments on real-world benchmarks demonstrate that TimeMM consistently outperforms state-of-the-art multimodal recommenders while maintaining linear-time scalability.
Apr 28, 2026

Control Your Queries: Heterogeneous Query Interaction for Camera-Radar Fusion

In autonomous driving, camera-radar fusion offers complementary sensing and low deployment cost. Existing methods perform fusion through input mixing, feature map mixing, or query-based feature sampling. We propose a new fusion paradigm, termed heterogeneous query interaction, and present ConFusion, a camera-radar 3D object detector. ConFusion combines image queries, radar queries, and learnable world queries distributed in 3D space to improve query initialization and object coverage. To encourage cross-type interaction among heterogeneous queries, we introduce heterogeneous query mixing (QMix), which performs dedicated cross-type attention after feature sampling to consolidate complementary object evidence. We further propose interactive query swap sampling (QSwap), which improves feature sampling by allowing related queries to exchange informative feature tokens under attention and geometric constraints. Experiments on the nuScenes dataset show that ConFusion achieves state-of-the-art performance, reaching 59.1 mAP and 65.6 NDS on the validation set, and 61.6 mAP and 67.9 NDS on the test set.