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Subretinal injection is a delicate vitreoretinal procedure requiring precise needle placement within the subretinal space while avoiding perforation of the retinal pigment epithelium (RPE), a layer directly beneath the target with extremely limited regenerative capacity. To enhance depth perception during cannula advancement, intraoperative optical coherence tomography (iOCT) offers high-resolution cross-sectional visualization of needle-tissue interaction; however, interpreting these images requires sustained visual attention alongside the en face microscope view, thereby increasing cognitive load during critical phases and placing additional demands on the surgeon's proprioceptive control. In this paper, we propose a structured, real-time sonification framework designed for extensible mapping of iOCT-derived anatomical features into perceptual auditory feedback. The method employs a physics-inspired acoustic model driven by segmented retinal layers from a stream of iOCT B-scans, with needle motion and injection-induced retinal layer displacements serving as excitation inputs to the sound model, enabling perception of tool position and retinal deformation. In a controlled user study (n=34), the proposed sonification achieved high retinal layer identification accuracy and robust detection of retinal deformation-related events, significantly outperforming a state-of-the-art baseline in overall event identification (83.4% vs. 60.6%, p < 0.001), with gains driven primarily by enhanced detection of injection-induced retinal deformation. Evaluation by experts (n=4) confirmed the clinical relevance and potential intraoperative applicability of the method. These results establish structured iOCT sonification as a viable complementary modality for real-time surgical guidance in subretinal injection.

Offline-to-online reinforcement learning harnesses the stability of offline pretraining and the flexibility of online fine-tuning. A key challenge lies in the non-stationary distribution shift between offline datasets and the evolving online policy. Common approaches often rely on static mixing ratios or heuristic-based replay strategies, which lack adaptability to different environments and varying training dynamics, resulting in suboptimal tradeoff between stability and asymptotic performance. In this work, we propose Reinforcement Learning with Optimized Adaptive Data-mixing (ROAD), a dynamic plug-and-play framework that automates the data replay process. We identify a fundamental objective misalignment in existing approaches. To tackle this, we formulate the data selection problem as a bi-level optimization process, interpreting the data mixing strategy as a meta-decision governing the policy performance (outer-level) during online fine-tuning, while the conventional Q-learning updates operate at the inner level. To make it tractable, we propose a practical algorithm using a multi-armed bandit mechanism. This is guided by a surrogate objective approximating the bi-level gradient, which simultaneously maintains offline priors and prevents value overestimation. Our empirical results demonstrate that this approach consistently outperforms existing data replay methods across various datasets, eliminating the need for manual, context-specific adjustments while achieving superior stability and asymptotic performance.

Purpose: This study investigates the transcription principles underlying Huìtóngguǎnxì Huáyíyìyǔ (HHY), a series of multilingual glossaries compiled by the Ming government between the fifteenth and sixteenth centuries for interpreter training. The study treats HHY not as a collection of isolated language materials, but as a coherent multilingual transcription system representing spoken forms of non-Chinese languages through Chinese characters. Methods: A substantial portion of HHY was digitized and aligned with Chinese phonological categories. Previous reconstructions of individual language sections were critically reviewed and integrated into a unified comparative database. The analysis focuses on cross-linguistic regularities in Main Transcription (MT) and Supplementary Transcription (ST) across eight language sections. Results: MT generally represents sounds compatible with the Chinese syllable structure of the period, whereas ST mainly encodes phonetic features less compatible with Chinese phonology. The analysis further shows that Chinese phonological categories were used more flexibly in foreign-language transcription than previously assumed. HHY therefore functioned as a relatively systematic method of phonetic approximation rather than a direct projection of Chinese phonology onto non-Chinese languages. Conclusion: HHY can be analyzed as an internally structured transcription system rather than merely as a collection of glossaries. More broadly, the study demonstrates that historical transcription systems can provide valuable evidence for historical phonology, particularly for under-documented Asian languages with limited historical records.

The Intelligence Impact Quotient (IIQ) is a composite metric intended to quantify the depth to which AI systems are integrated into organizational work and their impact. Rather than treating access counts or aggregate token volume as sufficient evidence of impact, IIQ combines a novelty-weighted, time-decayed token stock with usage frequency, a grace-period recency gate, organizational leverage, task complexity, and autonomy. The formulation produces a raw Intelligence Adoption Index (IAI) and a normalized 0-1000 IIQ index for comparison between heterogeneous users and units. We also derive sub-daily update rules and a bounded interpretation layer for estimated efficiency and financial impact. The paper positions IIQ as a deployment-oriented measurement framework: a formal proposal for tracking AI embedding in workflows, not a direct measure of model capability or a substitute for causal productivity evaluation. Synthetic scenarios illustrate how the revised metric distinguishes between frequent low-leverage use, semantically repetitive prompting, and more autonomous, higher-consequence AI-assisted work.

Pattern discovery in data plays a crucial role across diverse domains, including healthcare, risk assessment, and machinery maintenance. In contrast to black-box deep learning models, symbolic rule discovery emerges as a key data mining task, generating human-interpretable rules that offer both transparency and intuitive explainability. This paper introduces the Optimal Pattern Detection Tree (OPDT), a rule-based machine learning model based on novel mixed-integer programming to discover a single optimal pattern in data through binary classification. To incorporate prior knowledge and compliance requirements, we further introduce the Branching Structure Constraints (BSC) framework, which enables decision makers to encode domain knowledge and constraints directly into the model. This optimization-based approach discovers a hidden underlying pattern in datasets, when it exists, by identifying an optimal rule that maximizes coverage while minimizing the false positive rate due to misclassification. Our computational experiments show that OPDT discovers a pattern with optimality guarantees on moderately sized datasets within reasonable runtime.

Continual learning requires models to adapt to new data while preserving previously acquired knowledge. At its core, this challenge can be viewed as principled one-step adaptation: incorporating new information with minimal interference to existing representations. Most existing approaches address this challenge by modifying model parameters or architectures in a supervised, task-specific manner. However, the underlying issue is representational: tasks require distinct yet structured representations that can be selectively updated without disrupting representations, while structure should reflect intrinsic organization in the data rather than task boundaries. In sequential data, time-delayed dependencies provide a natural signal for uncovering this organization, revealing how fundamental representations give rise to more specific ones. Inspired by the modular organization of the human brain, we propose MoRe, a framework that identifies modularity in the representation itself rather than allocating it at the architectural level. MoRe decomposes knowledge into a hierarchy of fundamental and specific modules with identifiability guarantees, enabling principled module reuse, alignment, and expansion during adaptation while preserving old modules by construction. Experiments on synthetic benchmarks and real-world LLM activations demonstrate interpretable hierarchical structure, improved plasticity-stability trade-offs, suggesting MoRe as a principled foundation for continual adaptation

Wearable devices capture physiological and behavioral data with increasing fidelity, but the psychological context shaping these outcomes is difficult to recover from sensor data alone, limiting passive sensing utility for digital health. We examined whether ultra-brief naturalistic concern text could serve as a scalable complement to passive sensing. In a year-long study of 458 university students (3,610 person-waves) tracked with Oura rings, participants responded bimonthly to an open-ended prompt about what concerned them most; responses had a median length of three words. We compared dictionary-based, general pretrained, and domain-adapted NLP approaches using within-person mixed-effects models across nine sleep and physical activity outcomes. Weeks dominated by academic concern framing were associated with lower physical activity; weeks characterized by emotional exhaustion language were associated with poorer sleep quality and lower heart rate variability. General pretrained embeddings outperformed domain-adapted models for most outcomes, with domain adaptation showing relative advantage for autonomic outcomes. Zero-shot classification of concern topics produced no significant associations, while affective dimensions across all three methods were consistently associated with outcomes, indicating emotional register rather than topical content carries the signal. These findings offer design guidance: ultra-brief affective prompts enrich the psychological interpretability of passive physiological data at minimal burden.

We present a physics-informed framework for system identification based on randomized stable atomic features. Impulse responses are represented as random superpositions of stable atoms, namely damped complex exponentials associated with poles sampled inside a prescribed disk. Identification is then cast as a convex regularized least-squares problem with optional linear, second-order-cone, and KYP constraints. The approach generalizes random Fourier and random Laplace features to the damped, nonstationary regime relevant to engineering systems while retaining modal interpretability and scalable finite-dimensional computation. The main analytic point is an operator-theoretic Disk-Bochner viewpoint: positive measures over stable poles generate positive-definite kernels with a radius-dependent shift defect, while a converse scalar disk moment representation for an arbitrary kernel is characterized by subnormality of the canonical shift. We prove this statement, establish an RKHS-to-l1 embedding, show that sampled poles induce a valid finite atomic gauge, discuss random-feature convergence, and state sparse-recovery guarantees conditionally on the restricted-eigenvalue properties of the realized disk-Vandermonde or input-output design matrix. We also connect the normalized transfer function problem to Nevanlinna-Pick interpolation and LFT set-membership. The framework directly encodes stability margins, modal localization, DC-gain bounds, monotonicity, passivity, relative degree, settling-time targets, and time/frequency-domain error bounds. Numerical comparisons illustrate how physically meaningful priors can compensate for poor excitation and improve constrained impulse-response recovery in an under-informative data setting.

Generating realistic human motion is a central yet unsolved challenge in video generation. While reinforcement learning (RL)-based post-training has driven recent gains in general video quality, extending it to human motion remains bottlenecked by a reward signal that cannot reliably score motion realism. Existing video rewards primarily rely on 2D perceptual signals, without explicitly modeling the 3D body state, contact, and dynamics underlying articulated human motion, and often assign high scores to videos with floating bodies or physically implausible movements. To address this, we propose PhyMotion, a structured, fine-grained motion reward that grounds recovered 3D human trajectories in a physics simulator and evaluates motion quality along multiple dimensions of physical feasibility. Concretely, we recover SMPL body meshes from generated videos, retarget them onto a humanoid in the MuJoCo physics simulator, and evaluate the resulting motion along three axes: kinematic plausibility, contact and balance consistency, and dynamic feasibility. Each component provides a continuous and interpretable signal tied to a specific aspect of motion quality, allowing the reward to capture which aspects of motion are physically correct or violated. Experiments show that PhyMotion achieves stronger correlation with human judgments than existing reward formulations. These gains carry over to RL-based post-training, where optimizing PhyMotion leads to larger and more consistent improvements than optimizing existing rewards, improving motion realism across both autoregressive and bidirectional video generators under both automatic metrics and blind human evaluation (+68 Elo gain). Ablations show that the three axes provide complementary supervision signals, while the reward preserves overall video generation quality with only modest training overhead.

LLM-based web agents can navigate live storefronts, yet they often collapse to a single "average buyer" policy, failing to capture the heterogeneous and distributional nature of real buyer populations. Existing personalization methods rely on hand-crafted prompt-based personas that are brittle, difficult to scale, context-inefficient, and unable to faithfully represent population-level behavior. We introduce SimPersona, a novel framework that learns discrete buyer types from historical traffic and exposes them to LLM-based web agents as compact persona tokens. Given raw clickstreams, a behavior-aware VQ-VAE induces a discrete buyer-type space that captures the statistical structure of real buyer behavior and merchant-specific buyer population distributions. To provide behavior-specific guidance to LLM-based web agents, SimPersona maps each learned buyer type to a dedicated persona token in the LLM agent vocabulary and fine-tunes the agent with these tokens on real browsing traces. At inference, each synthetic buyer is assigned to a learned buyer type with a single encoder forward pass, requiring no retraining or store-specific prompt engineering. For population-level simulation, SimPersona samples buyer types from each merchant's empirical distribution over the learned VQ-VAE codebook and instantiates agents with the corresponding persona tokens, preserving merchant-specific buyer population distributions. Evaluated on $8.37$M buyers across $42$ held-out live storefronts, SimPersona achieves $78\%$ conversion-rate alignment with real buyers, exhibits interpretable behavioral variation across buyer types, and outperforms a baseline with $8\times$ more parameters on goal-oriented shopping tasks. We further release an open-source data pipeline that converts raw e-commerce event logs into buyer representations and agent-training traces.

The application of Large Language Models to Question Answering has shown great promise, but important challenges such as hallucinations and erroneous reasoning arise when using these models, particularly in knowledge-intensive, domain-specific tasks. To address these issues, we introduce Derivation Prompting, a novel prompting technique for the generation step of the Retrieval-Augmented Generation framework. Inspired by logic derivations, this method involves deriving conclusions from initial hypotheses through the systematic application of predefined rules. It constructs a derivation tree that is interpretable and adds control over the generation process. We applied this method in a specific case study, significantly reducing unacceptable answers compared to traditional RAG and long-context window methods.

Deep learning excels at prediction but often lacks finite-sample guarantees and calibrated uncertainty; RKHS (Reproducing Kernel Hilbert Space)-based methods provide those guarantees but struggle to adapt in high dimensions. We propose Wahkon, a deep RKHS superposition network that unifies Kolmogorov's superposition principle with RKHS regularization in the smoothing-spline tradition of Wahba. This yields a finite-dimensional deep representer theorem that makes training tractable and provides explicit layerwise complexity control. We show the penalized estimator is exactly the MAP (maximum a posteriori) estimate under a hierarchical Gaussian-process prior, extending the spline/GP duality to deep compositions. Using metric-entropy arguments, we establish minimax-optimal convergence rates under mild smoothness and clarify how depth and width trade off with regularity. Empirically, Wahkon outperforms multilayer perceptrons, Neural Tangent Kernels, and Kolmogorov--Arnold Networks across simulation benchmarks and a single-cell CITE-seq study. By unifying Kolmogorov's superposition principle with RKHS regularization, Wahkon delivers accuracy, interpretability, and statistical rigor in a single framework.

Brain-language model comparisons often interpret neural prediction scores as evidence that model representations capture brain-relevant language computation. We asked whether language models align with brains, and whether prediction scores are enough to support that claim, using L-PACT, a source-audited framework that evaluates predictive, relational, mechanism-stripping, and reliability-bounded evidence. Across primary naturalistic language neural datasets and derived language-model representations, L-PACT compared real model features with nuisance baselines and severe controls, tested whether model-to-brain profiles reproduced brain-to-brain patterns, recomputed held-out scores after mechanism stripping, and normalized evidence against brain-brain ceilings. The locked analysis set contains 414 predictive-control rows, 2304 relational profile rows, 4320 mechanism-stripping rows, 420 brain-brain ceiling rows, and 146 integrated decision rows. Assay-sensitivity checks showed that brain-brain reliability, brain-as-model run-to-run relational profiles, independent low-level neural and WAV-derived acoustic-envelope gates, and a deterministic implanted-signal simulation can produce positive evidence when expected. Nevertheless, no real model row passed the predictive, relational, mechanism-stripping, or operational Turing-bounded reliability gates; all 146 integrated rows were control-explained. Less stringent single-criterion rules would have counted raw positive predictive, relational, stripping-delta, and ceiling-normalized effects, but L-PACT downgraded them because controls explained the apparent evidence. In the analyzed derived artifact set, the tested language-model representations do not satisfy L-PACT alignment gates; apparent positives are converted into an auditable control-explained taxonomy rather than treated as structural alignment.

Differentiable Logics are deployed in neuro-symbolic learning tasks as a way of embedding logical constraints in the training objective of neural networks. A differentiable logic consists of a syntax to write logical properties and a semantics to interpret them as real-valued functions to be folded in the loss function. A defining trade-off of the field is that between logical properties of the connectives, and analytic concerns for the semantics, with both aspects being relevant in applications. At one extreme we find fuzzy logics, that have well-established algebraic and proof-theoretic foundations, and at the other ad-hoc differentiable logics like Fischer's DL2, conceived for deep learning applications. However, no satisfactory foundation has emerged yet. We propose a resolution to this long-standing tension via a novel logic, Quantitative Linear Logic (QLL), with foundational ambitions. Our design is driven by naturality -- the idea that, since logical constraints are translated to losses, the semantics of the connectives should be pertinent operations used in ML practice (that is, sum and log-sum-exp) on additive quantities (like logits). We then judge the result on two aspects: logical adequacy -- that they satisfy most of the standard logical laws of Linear Logic; and empirical effectiveness -- test-time performance (as measured by adversarial attacks) is well-correlated to the actual verification of the logical constraints (as measured by off-the-shelf neural network verifiers), which makes QLL stand out among SoTA techniques.

Multi-agent LLM systems usually collaborate by exchanging natural-language messages. This interface is simple and interpretable, but it forces each sender's intermediate computation to be serialized into tokens and then reprocessed by the receiver, thereby increasing the generated-token cost, prefill overhead, and KV-cache memory. We study an alternative communication interface: instead of appending a sender's message to the receiver's context, compile the sender's hidden states into a transient, receiver-specific weight perturbation. We introduce TFlow (Thought Flow), a weight-space communication framework for a known and fixed receiver architecture. For each query, frozen role-prompted sender agents process the input, and a learned parameter generator maps their internal activations into low-rank LoRA perturbations targeting the receiver's modules. These perturbations are fused and applied only during the receiver's generation, enabling instance-level adaptation without permanently changing the model or enlarging the receiver's text context. With three Qwen3-4B agents, TFlow improves over a standalone receiver by up to 8.5 accuracy points across five benchmarks while reducing processed tokens by up to 32.69%. Compared with a text-based three-agent baseline, it reduces total processed tokens by up to 83.27% and the wall-clock inference time by up to 4.6$\times$, while maintaining competitive accuracy on four of five benchmarks. These results suggest that transient low-rank weight perturbations can serve as an executable communication medium for efficient multi-agent LLM collaboration.

Contrastive learning (CL) aims to preserve relational structure between samples by learning representations that reflect a similarity graph. Yet, the geometry of the resulting embeddings remains poorly understood. Here we show that weighted InfoNCE objectives can be interpreted as Distance Geometry Problems, where the weighting scheme specifies the target geometry to be realized by the representation. This viewpoint yields exact characterizations of the optimal embeddings for several supervised and weakly supervised objectives. In supervised classification, both SupCon and Soft SupCon (a dense relaxation of it where pairs from distinct classes have small non-zero similarity) collapse samples within each class to a single prototype. However, while balanced SupCon recovers the classical regular simplex geometry, class imbalance breaks this symmetry: SupCon induces non-uniform inter-class similarities depending on class sizes, whereas Soft SupCon preserves a regular simplex geometry regardless of class imbalance. In continuous-label settings, our framework reveals a different failure mode: y-Aware CL generally cannot attain its entropic optimum unless the labels lie on a hypersphere, exposing a mismatch between Euclidean label weights and spherical latent similarity. By contrast, geometrically consistent choices such as Euclidean-Euclidean weighting or X-CLR admit unique optimal embeddings. Our results show that the choice of weighting scheme determines whether contrastive learning is geometrically realizable, degenerate, or inconsistent, providing a principled framework for designing contrastive objectives.

Natural-language software requirements are often ambiguous, inconsistent, and underspecified; in safety-critical domains, these defects propagate into formal models that verify the wrong specification and into implementations that ship unsafe behavior. We show that large language models, equipped with an SMT solver, can audit such requirements: translating them into formal logic, detecting ambiguity through stochastic variation in the generated formalization, and exposing inconsistency, vacuousness, and safety violations through solver queries on the resulting specification. We present VERIMED, a neurosymbolic pipeline that operationalizes this idea for medical-device software requirements, and report two findings. First, stochastic variation across independent formalizations is a signal of ambiguity: requirements that admit multiple plausible interpretations produce SMT-inequivalent formalizations, and bidirectional SMT equivalence checking turns this disagreement into a solver-checkable test. Second, the usefulness of symbolic feedback depends on its granularity: in counterexample-guided repair on a hemodialysis question-answering benchmark, concrete SMT counterexamples raise verified accuracy from 55.4% to 98.5%. Over an extensive experimental evaluation on open-source hemodialysis safety requirements, we show that the LLM-based approach in VERIMED successfully reduces ambiguity-sensitive requirements and enables rigorous auditing of software requirements through SMT-based queries.

Establishing trustworthy safety assurance for autonomous driving systems (ADSs) requires evidence that failures arise from avoidable system deficiencies rather than unavoidable traffic conflicts. Current adversarial simulation methods can efficiently expose collisions, but generally lack mechanisms to distinguish these fundamentally different failure modes. Here we present CARS (Context-Aware, Responsibility-attributed Scenario generation), a framework that integrates responsibility attribution directly into adversarial scenario generation. CARS combines context-aware adversary selection with a generative adversarial policy optimized in closed-loop simulation to construct collision scenarios that are both physically feasible and diagnostically attributable. Across benchmark datasets spanning heterogeneous national traffic environments, CARS consistently discovers feasible collision scenarios with high attribution rates under multiple regulation-prescribed careful and competent driver models. By coupling adversarial generation with normative responsibility assessment, CARS moves simulation testing beyond collision discovery toward the construction of interpretable, regulation-aligned safety evidence for scalable ADS validation.

Thermal infrared imaging is robust to illumination variations and smoke interference, making it important for all-weather perception. However, the lack of natural color and fine texture limits target recognition, human visual interpretation, and the transfer of visible-light models. Existing infrared colorization methods mainly rely on single-band images, where insufficient spectral cues may lead to structural distortion and semantic confusion. Although infrared hyperspectral images provide rich spectral responses and material information, existing single-band frameworks remain limited in modeling spatial-spectral coupling and weak texture details. To address these issues, this paper presents FSCM, a spectral-information-guided GAN framework. Within FSCM, a frequency-enhanced spatial-spectral state-space generator composed of cascaded FSB units is constructed. Each FSB integrates three complementary components: state-space modeling captures global spatial-spectral dependencies; the frequency enhancement module (FEM) combines multi-level wavelet decomposition and Fourier gating to recover structural contours, directional high-frequency details, and global frequency responses; and the dual-stream hybrid gating module (DGM) integrates deformation-aware sampling with sparse attention to enhance effective local structures and suppress background interference. Additionally, an online semantic segmentation-guided loss is introduced to constrain the generated results, improving semantic consistency in complex road scenes. Experiments show that FSCM outperforms existing infrared colorization methods in visual quality and semantic fidelity.

Robotic dexterous hands are central to contact-rich manipulation, with rapid progress driven by advances in hardware, sensing, control, simulation, and data generation. However, existing studies are often developed under different assumptions regarding hand embodiments, sensory configurations, task settings, training data, and evaluation protocols, making systematic comparison difficult and obscuring the developmental trajectory of the field. This survey provides a holistic review of dexterous hand research from four complementary aspects. First, we present a hardware-level analysis covering actuation, transmission, perception, and representative hand designs, highlighting the key trade-offs in force capability, compliance, bandwidth, integration, and system complexity. Furthermore, we review control and learning methods for dexterous manipulation from a methodological perspective, grouping representative works by major paradigms and tracing their evolution in chronological order. In addition, we consolidate datasets, modality design, and evaluation practices, which enables methodological progress to be interpreted together with the ways in which it is trained, benchmarked, and assessed. Finally, we discuss the major limitations of current dexterous hand research and summarize the corresponding future directions. By connecting hardware analysis, methodological development, data resources, and evaluation, this survey aims to provide a structured understanding of dexterous hand research and to clarify the most important open challenges for future study.

Most anomaly detection systems output scores rather than calibrated decisions, leaving practitioners to choose thresholds heuristically and without clear statistical interpretation. Conformal anomaly detection addresses this limitation by converting anomaly scores into calibrated p-values that are valid under the statistical assumption of data exchangeability, with a growing literature extending this idea beyond that setting. We present 'nonconform', a Python package for applying conformal anomaly detection within existing machine-learning workflows, and use it as the basis for an implementation-grounded introduction to the field. The package integrates with 'scikit-learn', 'pyod', and custom anomaly detectors, and provides a unified interface for calibration, p-value generation, and false discovery rate control. It supports several conformalization strategies, ranging from simple split-conformal calibration to more data-efficient and shift-aware extensions. Through a progression from foundational concepts to advanced conformalization strategies, complemented by code examples, the paper connects the statistical ideas behind conformal anomaly detection to their practical use in 'nonconform'. Empirical results demonstrate that the implemented methods enable statistically principled anomaly detection. Together, the package and exposition aim to make core conformal anomaly detection workflows more accessible and reproducible in experimental and production-oriented settings.

Diagnosing esophageal motility disorders pose significant challenges due to the complexity of high-resolution impedance manometry (HRIM) data and variability in clinical interpretation. This work explores the feasibility of a multimodal Machine Learning (ML)-based classification approach that combines HRIM recordings with patient-specific information and incorporates a graph-based modeling of esophageal physiology. We analyze HRIM recordings with corresponding patient information from 104 patients with esophageal motility disorders. Patient data includes demographic, clinical, and symptom information extracted from structured questionnaires and free-text notes using keyword detection and large language model-based processing. HRIM data is represented as spatio-temporal graphs, where nodes correspond to pressure values along the esophagus and edges encode spatial adjacency and impedance dynamics. A graph neural network (GNN) is applied to learn physiologically meaningful representations, which are fused with patient embeddings for multi-category, multi-class classification of swallow events. The impact of patient features and graph-based modeling is evaluated by ablation studies and comparison to vision-based classifier baselines. The proposed multimodal approach indicates improvements over models that rely solely on HRIM-derived features across all classification categories. Additionally, the graph-based modeling provides gains compared to vision-based baselines. Our experiments systematically assess the complementary contribution of multiple modalities, as well as demonstrate the feasibility of our proposed graph-based approach. Our initial findings demonstrate that integrating patient-level data with graph-based representations of HRIM signals appears to be a promising direction for more accurate classification of esophageal motility disorders.

Understanding how deep neural networks learn useful internal representations from data remains a central open problem in the theory of deep learning. We introduce Neural Low-Degree Filtering (Neural LoFi), a stylized limit of gradient-based training in which hierarchical feature learning becomes an explicit iterative spectral procedure. In this limit, the dynamics at each layer decouple: given the current representation, the next layer selects directions with maximal accessible low-degree correlation to the label. This yields a tractable surrogate mechanism for deep learning, together with a natural kernel-space interpretation. Neural LoFi provides a mathematically explicit framework for studying multi-layer feature learning beyond the lazy regime. It predicts how representations are selected layer by layer, explains how emergence of concepts arises with given sample complexity,and gives a concrete mechanism by which depth progressively constructs new features from old ones through low-degree compositionality. We complement the theory with mechanistic experiments on fully connected and convolutional architectures, showing that Neural LoFi improves over lazy random-feature baselines, recovers meaningful structured filters, and predicts representations aligned with early gradient-descent feature discovery with real datasets.

This study investigates deep self-disclosure toward generative AI by examining perceived non-humanity and structural similarity as psychological factors beyond anthropomorphism. Perceived non-humanity may reduce evaluation apprehension, whereas structural similarity refers to the perceived logical alignment between a user's thinking and AI responses. Using cross-sectional survey data from 2,400 participants collected in 2025, this study analyzed associations with both the occurrence and depth of self-disclosure. Logistic regression indicated that the group high in both perceptions (Segment D) showed a significantly higher likelihood of disclosure than the baseline group (Segment A; OR = 11.35). ANOVA further showed significant between-group differences in disclosure depth. The findings suggest that trust-related behavior in deep self-disclosure may involve factors other than anthropomorphic perception. Because the study is exploratory and based on self-reported survey data, the results should be interpreted as associative rather than causal, and future longitudinal or experimental research is needed.

During thDuring the last few years, the term Mechanistic Interpretability, a specific area, under the umbrella of explainable artificial intelligence (XAI), has been introduced, to explain the decisions made by complex machine learning (ML) models in critical systems like UAV intrusion detection systems (UAVIDS). In this paper, we apply best-practices for data pre-processing and examine a wide range of tree-ensembles, deep neural networks, hybrid stacking models and the latest ensemble neural networks to detect intrusions in UAV, with stratified 10-fold cross validation. With our top-performing model, XGBoost, we proceed to Shapley Additive explanations (SHAP), to analyze the global and local feature importances and understand which features, each attack targets, to mimic normal traffic and where the misclassifications occur. Furthermore a distribution analysis follows, by visually comparing violin plots and the curves of kernel density estimations. With the Westfall-Young permutation test for multiple comparisons, the Bandwidth optimization of the KDEs and the selection of Jensen-Shannon Distance for the test, we discover the true causes of false predictions, observed in Wormhole and Blackhole attacks in UAVIDS-2025. The findings provide robust, reliable and explainable models for UAV intrusion detection, along with statistical insights, which capture and clarify the masked nature of the attacks, regarding the challenge of Density Support Intersection, between these attacks, in this dataset.

Intensive care units (ICU) generate long, dense and evolving streams of clinical information, where physicians must repeatedly reassess patient states under time pressure, underscoring a clear need for reliable AI decision support. Existing ICU benchmarks typically treat historical clinician actions as ground truth. However, these actions are made under incomplete information and limited temporal context of the underlying patient state, and may therefore be suboptimal, making it difficult to assess the true reasoning capabilities of AI systems. We introduce RealICU, a hindsight-annotated benchmark for evaluating large language models (LLMs) under realistic ICU conditions, where labels are created after senior physicians review the full patient trajectory. We formulate four physician-motivated tasks: assess Patient Status, Acute Problems, Recommended Actions, and Red Flag actions that risk unsafe outcomes. We partition each trajectory with 30-min windows and release two datasets: RealICU-Gold with 930-window annotations from 94 MIMIC-IV patients, and RealICU-Scale with 11,862 windows extended by Oracle, a physician-validated LLM hindsight labeler. Existing LLMs including memory-augmented ones performed poorly on RealICU, exposing two failure modes: a recall-safety tradeoff for clinical recommendations, and an anchoring bias to early interpretations of the patient. We further introduce ICU-Evo to study structured-memory agents that improves long-horizon reasoning but does not fully eliminate safety failures. Together, RealICU provides a clinically grounded testbed for measuring and improving AI sequential decision-support in high-stakes care. Project page: https://chengzhi-leo.github.io/RealICU-Bench/

Surgical scene understanding is a cornerstone of computer-assisted intervention. While recent advances, particularly in surgical image segmentation, have driven progress, real-world clinical applications require a more holistic understanding that jointly captures procedural context, semantic reasoning, and precise visual grounding. However, existing approaches typically address these components in isolation, leading to fragmented representations and limited semantic consistency. To address this limitation, we propose SurgMLLM, a unified surgical scene understanding framework that bridges high-level reasoning and low-level visual grounding within a single model. Given surgical videos, SurgMLLM fine-tunes a multimodal large language model (MLLM) to support structured interpretability reasoning, which is used to jointly model phases, instrument-verb-target (IVT) triplets, and triplet-entity segmentation tokens. These tokens are then temporally aggregated and serve as prompts for a segmentation network, enabling accurate pixel-wise grounding of triplet instruments and targets. The entire framework is trained end-to-end with a unified objective that couples language-based reasoning supervision with visual grounding losses, promoting coherent cross-task learning and clinically consistent scene representations. To facilitate unified evaluation, we introduce CholecT45-Scene, extending CholecT45 dataset with 64,299 frames of pixel-level mask annotations for instruments and targets, aligned with existing triplet labels. Extensive experiments show that SurgMLLM significantly advances surgical scene understanding, improving the primary triplet recognition metric AP_IVT from 40.7% to 46.0% and consistently outperforming prior methods in phase recognition and segmentation. These results highlight the effectiveness of unified reasoning-and-grounding for reliable, context-aware surgical assistance.

Reusable skills have become a core substrate for improving agent capabilities, yet most existing skill packages encode reusable behavior primarily as textual prompts, executable code, or learned routines. For visual agents, however, procedural knowledge is inherently multimodal: reuse depends not only on what operation to perform, but also on recognizing the relevant state, interpreting visual evidence of progress or failure, and deciding what to do next. We formalize this requirement as multimodal procedural knowledge and address three practical challenges: (I) what a multimodal skill package should contain; (II) where such packages can be derived from public interaction experience; and (III) how agents can consult multimodal evidence at inference time without excessive image context or over-anchoring to reference screenshots. We introduce MMSkills, a framework for representing, generating, and using reusable multimodal procedures for runtime visual decision making. Each MMSkill is a compact, state-conditioned package that couples a textual procedure with runtime state cards and multi-view keyframes. To construct these packages, we develop an agentic trajectory-to-skill Generator that transforms public non-evaluation trajectories into reusable multimodal skills through workflow grouping, procedure induction, visual grounding, and meta-skill-guided auditing. To use them, we introduce a branch-loaded multimodal skill agent: selected state cards and keyframes are inspected in a temporary branch, aligned with the live environment, and distilled into structured guidance for the main agent. Experiments across GUI and game-based visual-agent benchmarks show that MMSkills consistently improve both frontier and smaller multimodal agents, suggesting that external multimodal procedural knowledge complements model-internal priors.

While many-shot ICL achieves remarkable performance, prior studies of its scaling behavior have mainly focused on non-reasoning tasks. In this work, we study many-shot ICL on reasoning tasks, with a particular focus on many-shot chain-of-thought in-context learning (CoT-ICL). Analyzing across non-reasoning and reasoning tasks and across non-reasoning and reasoning-oriented LLMs, we identify several distinctive properties of many-shot CoT-ICL. We further interpret these findings by viewing many-shot CoT-ICL as in-context test-time learning rather than scaled pattern matching, and suggest two principles: (i) demonstrations should be easy for the target model to understand, and (ii) they should be ordered to support a smooth conceptual progression. Guided by the principle, we propose Curvilinear Demonstration Selection (CDS), a simple ordering method that yields up to a 5.42 percentage-point gain on a math task with 64 demonstrations. Overall, our results reframe the long context window from a retrieval buffer into a structured curriculum for in-context test-time learning.

Large language models achieve strong performance in language generation and knowledge-intensive tasks, yet remain limited in settings requiring causal reasoning, persistent state tracking, and long-horizon planning. We argue that these limitations may arise from an objective-level mismatch between sequence prediction and reasoning over latent environment dynamics. To formalize this distinction, we introduce Latent Dynamics Inference (LDI), a conceptual perspective that interprets language and multimodal observations as partial evidence of underlying transition dynamics. To empirically investigate this perspective, we introduce Flux, a sequential reasoning environment specified entirely through natural-language rules. As a proof-of-concept case study, the rules are first compiled into an explicit state-transition simulator, illustrating that structured latent transition dynamics can, in some cases, be operationally extracted from textual rule descriptions. This enables a controlled comparison between the LLMs operating purely over textual observations and reinforcement-learning agents trained directly within the extracted latent state space. Within this case study, agents operating with explicit access to the latent state space exhibit substantially more stable behavior in long-horizon gameplay, achieving an aggregate win rate of approximately 79% versus 11% for LLMs. Qualitative analysis further reveals failure modes consistent with unstable persistent state tracking, including invalid actions, state-tracking errors, and short-horizon reasoning failures. The complete implementation of the Flux environment available at https://github.com/FeisalAlaswad/FLUX-RL-Agent Within the evaluated setting, these results suggest that strong sequence prediction alone may struggle to support robust long-horizon dynamic reasoning without mechanisms for persistent state tracking and transition modeling