Medical Image Segmentation

Recent crack segmentation methods often follow generic semantic segmentation designs, using stronger backbones, hybrid CNN-Transformer-Mamba encoders, and auxiliary enhancement branches. Although effective, this raises whether stronger generic feature mixing is the most suitable direction for crack segmentation. We instead formulate crack segmentation as sparse structural recovery. Cracks have limited category-level semantics but strong morphological regularities, being thin, sparse, anisotropic, locally fragmented, and easily confused with textures or shadows. Thus, the key bottleneck lies in preserving weak structural evidence, recovering directional continuity, and suppressing background coupling. We propose RIFT, a compact family of morphology-aligned crack segmentation models. Rather than compressing a complex generic architecture, RIFT is simple by design, preserving local evidence, aggregating cooperative directional continuity, and restoring crack structures through lightweight multi-scale fusion. Experiments on four public benchmarks show that RIFT achieves the best or tied-best results across the 16 main metrics against reproduced representative baselines. RIFT-B gives the strongest overall accuracy, while RIFT-T provides the best deployment efficiency with only 0.47M parameters and high inference speed. Topology-aware evaluation, ablations, transfer experiments, and visualizations further verify that task-aligned simplicity can match or surpass complex hybrid architectures when its inductive bias fits crack morphology. Code: https://github.com/xauat-liushipeng/RIFT

Accurate 3D medical image segmentation requires both long-range volumetric context and fine boundary preservation. CNN-based methods have limited global dependency modeling, while Transformer-based models are often computationally expensive for dense 3D inputs. Recent Mamba-based methods provide an efficient alternative, but existing volumetric designs still depend on repeated high-resolution scanning, forward-only sequential modeling, and fixed directional summation, causing high cost, scan-order bias, and suboptimal directional aggregation. We propose BiSegMamba, an efficient bidirectional tri-oriented Mamba network for 3D medical image segmentation. BiSegMamba follows a compact-to-detail design, where a progressive compacting stem (PCS) enables efficient latent-space reasoning while retaining shallow high-resolution features for reconstruction. A multi-scale spatial mixer (MSSM) captures local anatomical patterns in early stages, and the proposed bidirectional tri-oriented Ortho Mamba (Bi-ToOM) block models long-range dependencies from multiple orthogonal views using jointly processed forward and backward scan sequences. Adaptive directional fusion (ADF) learns input-dependent channel-wise weights across scan orientations, replacing fixed summation with orientation-aware fusion. Experiments on a collected carotid CTA dataset and three public benchmarks, BraTS2023, ACDC, and AMOS-CT, show that BiSegMamba generalizes well across vascular, cardiac, brain tumor, and abdominal multi-organ segmentation tasks. Compared with SegMamba-V2, BiSegMamba achieves slightly better performance on BraTS2023 and clear improvements on ACDC and the carotid dataset, while reducing computational cost by up to 77.9% FLOPs, demonstrating a strong accuracy-efficiency balance for general 3D medical image segmentation.

Semantic road segmentation is important for autonomous driving, but existing methods suffer severe performance degradation under low-light conditions. Many existing multi-modal fusion methods do not explicitly adapt to illumination-dependent changes in modality reliability, which can propagate degraded RGB features into the fused representation at night. We propose IAF-Net (Illumination-Adaptive Fusion Network), an end-to-end framework with illumination-adaptive fusion for robust road segmentation across different lighting conditions. It dynamically adjusts fusion weights of RGB and geometric features via the core Illumination-Adaptive Fusion (IAF) module, and enhances low-light feature selection with a brightness-modulated attention decoder. We also construct two dedicated datasets: nuScenes Nighttime Road Segmentation (nuScenes-NRS) and CARLA Multi-Weather Road Segmentation (CARLA-MWRS). Experiments on nuScenes-NRS show state-of-the-art overall performance among the compared methods, while CARLA-MWRS further validates robustness across adverse weather conditions. Ablation studies on a 40% training subset further highlight the importance of the IAF module, which provides the largest individual gain of 0.70% in MaxF.

Moving Object Segmentation (MOS) aims to discover, segment, and track objects that move independently of the camera. Current MOS methods, however, exhibit two fundamental limitations: they rely on pre-computed 2D auxiliary modalities such as optical flow or point trajectories that lack 3D geometric information, and they treat motion as a sequence-level attribute, overlooking the instantaneous motion state of each object. We address both by grounding MOS in 3D space and time, and propose GMOS, a framework that operates directly on RGB video to produce 3D-aware, temporally fine-grained segmentation of multiple moving objects, alongside a foreground--background variant GMOS-S for faster deployment. To support training and evaluation in this regime, we curate GMOS-2K, a dataset of 2,210 real-world videos with per-object temporal motion annotations drawn from five established Video Object Segmentation (VOS) benchmarks, and formalise MOS-I ("I" for instantaneous), a temporally fine-grained evaluation protocol with three complementary metrics. GMOS achieves state-of-the-art results across MOS, MOS-I, and Unsupervised VOS benchmarks, while running significantly faster than prior multi-object MOS methods and supporting online inference for streaming deployment.

Reliable semantic segmentation for mobile robots requires both accurate dense prediction and robust uncertainty estimation under distribution shift. Strong uncertainty baselines such as Monte Carlo Dropout often require repeated stochastic forward passes and are difficult to deploy on edge platforms. We propose Energy-Aware NECO, a single-pass pixel-wise out-of-distribution (OOD) detector for semantic segmentation. The method combines a centered NECO-style geometric ratio computed from decoder features with a logit-based Energy score. Both components are standardized using statistics fitted on a pure in-distribution validation split and fused through a convex combination. We evaluate the method on the miniMUAD subset using true pixel-level OOD labels. The proposed hybrid score achieves an AUROC of 0.8539, outperforming NECO-only (0.8280), Energy-only (0.8171), and an ensemble predictive-entropy baseline (0.8124). Additional qualitative and operating-point analyses show that the hybrid detector improves overall ranking performance while preserving the efficiency advantages of a single-pass design. Code is available at https://github.com/boyuan-zhangx/Energy-Aware_NECO

Self-supervised learning (SSL) has produced a diverse landscape of vision transformers (ViTs) whose pretrained representations support a wide range of downstream tasks. Towards a better understanding of these models, a body of work has assessed the mechanics of their self-attention as well as the types of information captured across their representations, revealing, for example, stark differences between models trained with contrastive learning (CL) and masked image modeling (MIM). However, the total of these advances on model understanding has to date not yet fully permeated a larger community, where, e.g., insights that are specific to CL models are still at times generalized to MIM models. To make model understanding straightforward and intuitive for a broad community, we propose a simple and easily interpretable visualization protocol. Our protocol is based on visualizing unsupervised semantic segmentation results, yet by no means do we focus on top segmentation performance. Instead, our protocol allows us to easily convey model behavior that consistently emerges across images. Benchmarked on a diverse set of SSL models across layers and representations, our protocol allows us to gain novel insights into distinct positional biases and scaling behaviors, including, e.g., strong boundary artifacts in DINOv3-Large model tokens. These novel insights come on top of more easily conveying a range of previous findings. Our protocol further allows us to clearly visually convey and distinguish between positional effects and the closely related but distinct locality bias, the latter being much more extensively studied in the literature so far. Our protocol is publicly available, serving to catalyze further model understanding for a broad community.

LLM-conditioned segmentation has recently advanced rapidly by coupling large language models with iterative mask generation frameworks. However, we identify a persistent failure mode in current propose-then-select pipelines. Although high-quality mask candidates are often generated, the final prediction may fail to match the given linguistic condition. This failure arises because language semantics are typically used as static prompts or post-hoc matching signals, rather than participating in the iterative mask generation process. Through systematic analysis, we show that many errors stem from semantic misalignment rather than poor mask quality. To address this issue, we propose FlowSeg, which introduces dynamic semantic guidance via a bidirectional semantic flow between intermediate decoding states and LLM-derived condition embeddings throughout the generation process. Language conditions actively guide mask refinement at each stage, while condition embeddings are progressively updated by emerging visual evidence. This design yields semantically grounded mask representations and visually aligned language conditions, enabling more reliable matching. We further incorporate a lightweight boundary-aware refinement to selectively enhance uncertain regions without perturbing confident interiors. Extensive experiments on referring expression segmentation and reasoning segmentation tasks demonstrate that FlowSeg consistently improves language-mask alignment and achieves state-of-the-art performance. Project page: https://zkzhang98.github.io/FlowSeg_page

Chain-of-thought traces from large reasoning models can span tens of thousands of tokens, yet we lack a vocabulary for describing their internal structure. Previous methods developed to analyze chain-of-thought traces are either too rigid or not expressive enough, failing to capture features across domains and models. To remedy this, we develop ReasonOps, an unsupervised, expressive method for annotating chain-of-thought traces, providing succinct universal operators. Using ReasonOps, we analyze 44,662 traces from 12 thinking LLMs spanning 6 families across 8 reasoning benchmarks and discover that they share a common compositional structure: 7 recurring reasoning operators -- discourse-level moves such as backtracking, inferring, and hypothesizing -- that emerge from unsupervised clustering of sentence-initial 3-token pivots. These operators appear across every model family and benchmark domain, confirmed by three independent LLM judges who classify held-out samples at 70 -76% accuracy. We analyze the structure of operators on easy vs. hard problems, revealing that reflective operators are more helpful on hard problems and harm performance on easy problems. Operator sequences are highly model-identifying: a classifier trained on operator distributions alone recovers the source model with macro-AUC, revealing that each model family has a distinctive reasoning fingerprint. Structural operator features predict within-problem answer correctness well above baselines. Classifiers built on these operators reach WP-AUC and on AIME specifically. ReasonOps further enables early quality estimation well before the trace completes: we predict at WP-AUC for only 50% of the trace. The ReasonOps pipeline is unsupervised and annotation-free, enabling deep insights into LLM reasoning traces as well as strong downstream results on model identification and correctness prediction.

In this work, we present a multiscale kinetic framework for consensus-based image segmentation. By interpreting an image as a system of interacting particles, each pixel is characterised by its spatial position and an internal feature encoding color information. We introduce a coupled interaction scheme governing the evolution of particles in both position and feature spaces, from which we derive a kinetic formulation for the particle density in the space-feature domain combining transport, aggregation, and diffusion effects. Furthermore, through a suitable scaling, we obtain a first-order macroscopic model describing the evolution of the fraction of pixels carrying information on the fraction of pixels having a certain feature. Based on this reduced-complexity model, we present a data-oriented approach where we make use of particle-based optimisation techniques for the accurate segmentation of images. Numerical tests show the effectiveness of the proposed framework and its robustness under different noise conditions.

Mobile robot path planning methods are often constrained by vast search spaces, resulting in latency in samplingbased algorithms. Learning-based approaches frequently suffer from local region fragmentation and global topological inconsistency. To tackle the problem, we present the Connectivity- Preserving Region Proposal Network (CP-RPN), a segmentationguided model designed to predict compact and topologically connected candidate regions, significantly compressing the search space. Specifically, we design a segmentation model that leverages a Deformable Attention Transformer (DAT) to capture long-range dependencies for global connectivity, with a Deconvolutional decoder to preserve fine-grained spatial details. To guarantee the connectivity of the predicted mask, we design a composite loss function that combines Cross-Entropy loss for pixelwise supervision, a Connectivity-Aware loss to enhance local coherence, and a Topological Continuity loss based on persistent homology to enforce global connectivity. Building on these highconnectivity corridor-like regions, the Voronoi diagram is used to plan the path, backed by a local A* fallback mechanism to ensure robustness. Experimental results demonstrate that CPRPN reduces the candidate region size by over 60.13% compared to the MPT baseline and achieves deterministic low-latency planning (avg. 0.11s) with a 99.60% success rate, outperforming traditional sampling-based algorithms in stability.

Vision-language segmentation models have recently achieved strong performance by leveraging high-level semantic object categories expressed in natural language. However, this semantic dependence limits their ability to reason about intrinsic visual properties such as shape, geometry, or texture, which are essential in many real-world applications. In this work, we introduce Semantic-Agnostic aNd Shape-Aware (SANSA) segmentation, a new paradigm that requires segmentation models to operate solely from non-semantic textual descriptions. To this end, we propose two strategies to generate SANSA segmentation prompts based on either dictionary constraints or example guidance, both generating semantic-agnostic textual descriptions. These prompts are then used to finetune segmentation models under semantic-agnostic supervision. Experiments show that finetuning on SANSA prompts yields up to a 20% mIoU improvement on this new segmentation task, compared to pretrained state-of-the-art models, while maintaining strong performance on standard semantic prompts. These results highlight the importance of low- and mid-level visual reasoning for improving the generalization and controllability of vision-language segmentation models.

Dense semantic segmentation is essential for autonomous driving, yet many multi-modal datasets lack pixel-level annotations. The Zenseact Open Dataset (ZOD) provides rich multi-sensor data but only bounding-box labels, limiting its use for segmentation research. Our primary contribution is a Segment Anything Model (SAM)-based annotation pipeline that produces dense, pixel-level annotations for ZOD by converting bounding boxes into semantic masks. In this pilot study, we process over 100,000 frames and manually curate a 2,300-frame subset (36% acceptance rate) to establish a reliable baseline. Using these annotations, we evaluate transformer-based CLFT and CNN-based DeepLabV3+ architectures across diverse weather conditions, achieving up to 48.1% mIoU with CLFT-Hybrid. To address extreme class imbalance, where pedestrians, cyclists, and signs constitute less than 1% of pixels, we explore specialized models targeting rare classes. We further validate the pipeline on the Iseauto autonomous-vehicle platform, achieving 77.5% mIoU, and show that SAM-derived representations transfer effectively across sensor configurations via bidirectional transfer learning. All code and annotations are released to support reproducible research.

Colo-segment recognition in colonoscopy videos is a key requirement for many downstream tasks, but existing automatic recognition methods only use colonoscopy images without fully exploiting the use of temporal information, leading to poor performance. Additionally, relevant public video-based datasets are in scarcity. To tackle this problem, we curate and release a labeled dataset specifically for the task of colo-segment recognition. In addition, we propose a two-stage deep learning-based framework, Colo-Segment Recognition via SpatioTemporal Network (ST-ColoNet), for the task of colo-segment recognition from colonoscopy videos which includes the Colorlaus module that uses metric learning to optimize edge-mediated spatial feature extraction, as well as the Full-Temp module which combines three self-attention patterns to better approximate full self-attention on long colonoscopy sequences and optimize temporal feature aggregation. Through extensive ablation experiments, we show that our framework is capable of achieving state-of-the-art performance on the task of colo-segment recognition, achieving an accuracy of 81.0% and F1-score of 70.7%, which is a tremendous improvement over state-of-the-art methods.

This paper describes our approach for the 8th UG2+ Workshop (CVPR 2026) Track~2, which targets semantic segmentation of outdoor scenes degraded by five weather conditions: blur, darkness, snow, haze, and glare. A central challenge we observe is a severe generalization gap -- models that perform well on the validation set often collapse on the test set. For instance, SegFormer-B5 drops 16.1 mIoU points from validation to test, suggesting that model capacity alone is insufficient for robustness. We investigate whether a carefully designed training recipe, rather than architectural complexity, can address this gap. Starting from a pre-trained SegMAN-S backbone, we systematically study the effects of domain-adaptive fine-tuning, multi-source data mixing, scene-balanced sampling, and synthetic degradation augmentation. Our final system achieves 59.9% mIoU on the official test set while maintaining a validation-test gap of only 6.5 points -- less than half that of larger models. We analyze negative results from architectural modifications, loss function variants, and model scaling to provide practical insights for weather-robust segmentation under limited data.

Recent segmentation models couple large language models (LLMs) with mask decoders to ground complex language expressions into masks, yet their instructions remain target-referential: they describe, constrain, or imply the region to be segmented. However, in real-world embodied interaction, human instructions are often at the intent-level, which includes the desired outcome without naming the region that enables it. To bridge this gap, we introduce SegWorld, where the model reasons about the scene through a multi-level visual chain-of-thought (CoT) before committing to a mask. Before receiving any instructions, it proactively observes the scene, describing visible objects and inferring plausible events they may support. Given an instruction, it continues the chain: from the object relevant to the intent, through the action that satisfies it, to the physical interaction site, the object part that affords the action. We formalize SegWorld as probabilistic inference, in which proactive observation supplies a linguistic scene context that improves mask prediction when instructions are given at the level of intent. We construct an intent-to-part benchmark for evaluating affordance-bearing part segmentation from high-level goals. Experiments show SegWorld matches instruction-driven baselines on target-referential instructions and improves substantially on intent-level ones.

Terrain understanding is fundamental for mobile robots operating in unstructured outdoor environments. Existing vision-based traversability estimation methods rely on robot-specific annotations or semantic class mappings, limiting transferability across platforms and requiring costly re-annotation when robot capabilities change, while standard semantic segmentation methods only focus on specific predefined classes, which do not capture the variety of terrains. In this work, we propose a transformer-based architecture that jointly performs class-specific semantic segmentation and class-agnostic terrain segmentation within a unified network, called Trinity. Terrain regions are segmented based solely on visual appearance, without predefined semantic labels or robot-dependent traversability scores. This formulation enables the learning of robot-agnostic visual terrain priors that can be combined with robot-specific experience for downstream tasks such as traversability estimation, visual odometry, and mission planning. To enable large-scale training with diverse terrain appearances, we extend the OAISYS simulator and introduce RUGDSynth, a synthetic dataset inspired by RUGD with class-agnostic terrain samples. Furthermore, we present the EXTerra Dataset, providing real-world images annotated with both class-specific and class-agnostic terrain labels. Experiments demonstrate the feasibility of the proposed task and the effectiveness of our joint segmentation approach in complex outdoor environments. Code and datasets will be released with this publication (after review).

Testing object detectors in safety-critical domains requires semantically meaningful probes beyond pixel-level corruptions. We present SemProbe, a tool for semantic robustness probing: users upload deployment images, create masks manually or automatically, select operational design domain-derived factors (or custom prompts), and run diffusion-based controlled inpainting. The system supports batch jobs, parallel seed/workflow variations, and configurable generation parameters. After each output, model inference runs automatically and displays annotated before/after comparisons with performance deltas. All probes are logged as structured artifacts, enabling traceable robustness evidence aligned with safety evaluation workflows. We demonstrate \textsc{SemProbe} on hand detection for dimension saws, targeting factors from insurance-oriented test criteria.

Real-time semantic segmentation models offer an excellent balance between accuracy and inference speed. However, deploying these models in dynamic real world environments often requires the ability to learn novel classes incrementally without retraining on the entire dataset. This capability is known as continual learning. In this regard, the standard fine-tuning methods in deep learning often fail due to catastrophic forgetting, where the model learns new information but forgets previously trained and learned classes. Contributing to this crucial domain, the current paper proposes a novel continual learning framework tailored for PIDNet, which is a widely cited state-of-the-art real-time semantic segmentation model. Our method, PILOT(Parallel Incremental Learning Over Time), introduces a real-time and lightweight strategy by implementing a parallel Derivative-branch (D-branch) designed to capture the high frequency boundary information of novel classes while freezing the trained parameters of the original segmentation network. This novel setup allows the model to adapt to new semantic categories while preserving the knowledge of previously learned classes. By using only data associated with the new class, our model significantly reduces training overhead. Experimental results demonstrate that our approach successfully segments new classes while maintaining high mean Intersection over Union (mIoU) on the original base classes, thereby comfortably outperforming all major continual learning approaches in this domain. Overall, PILOT is shown to effectively mitigate catastrophic forgetting with minimal impact on inference latency, thus maintaining real-time performance.

Accurate pancreas segmentation is critical for early cancer diagnosis, where annotation scarcity necessitates Semi-Supervised Learning (SSL). However, due to significant inter-sample morphological variability, existing SSL methods face severe generalizability limitations under sparse supervision, leading to the Supervision Bias problem. To address this, we propose Structural Consensus-based KAN Prototype Learning (SCKAN), which constructs the first cross-sample structural consensus learning with Kolmogorov-Arnold Networks (KANs), to achieve more generalizable and accurate segmentation. Specifically, SCKAN contains two key designs: Structure-constrained Prototype Consistency Learning (SPCL), which prompts unbiased structural representation by enforcing cross-sample consistency via prototype-level contrastive optimization, and Consensus-based Kolmogorov-Arnold Fusion (CKaF), which reduces morphology-specific bias by aggregating stable consensus and filtering sample-wise noise via KAN's adaptive B-spline nonlinearity. Extensive experiments on two public pancreas datasets demonstrate the effectiveness of SCKAN. Code is at https://github.com/rhodaliu17/SCKAN.

Liver surface landmark detection is a fundamental prerequisite for anatomical guidance in laparoscopic liver surgery. However, it remains unreliable in practice due to two pervasive challenges: illumination attenuation in underexposed regions and the structural mismatch between pixel-wise localization and continuous curvilinear geometry. To address these limitations, we propose A2ONet, an attenuation-resilient alternating optimization network for robust liver landmark detection. To mitigate illumination attenuation, A2ONet embraces an illumination field compensation (IFC) block that adaptively enhances dark regions while preserving structural consistency. Meanwhile, we introduce a lightweight frequency-orientation selective filter (FOSF) to suppress repetitive texture interference and preserve salient curvilinear cues. Building upon these resilient representations, we design an alternating seg-curve optimization (ASCO) decoder that iteratively couples dense segmentation with explicit curve modeling, enabling mutual guidance to optimize both structural continuity and endpoint localization. Extensive evaluations on L3D-2K, L3D, and P2ILF demonstrate consistent improvements over competitive methods, establishing a more reliable foundation for intraoperative anatomy guidance. Our code will be available at https://github.com/hyperiondk115/A2ONet.

Deploying high-performing 3D medical image segmenters (e.g., nnU-Net) is often limited by memory footprint and inference latency. Compression is therefore necessary, but compact 3D encoders tend to lose fine structural cues (small lesions and sharp boundaries) as downsampling repeats across multi-resolution stages. We propose Detail Consistent Distillation (DCD), a stage-wise distillation framework that preserves structural detail across scales by aligning teacher-student features in a wavelet-decomposed representation. At each encoder stage, DCD distills directional detail components in the wavelet domain while leaving the coarse approximation comparatively unconstrained, avoiding over-regularization of global semantics. DCD is used only during training and introduces no inference-time overhead. Experiments on the BraTS 2024 and ISLES 2022 benchmarks demonstrate that our approach achieves superior performance in MRI segmentation using 3D multi-modal data. Code and implementation details for DCD are publicly available at https://github.com/ClinicaAlpha/DCD-3D-MedSeg.

Semantic segmentation in complex environments such as urban driving scenes remains challenging under adverse lighting conditions, where RGB images alone provide insufficient information. RGB-Thermal fusion leverages the complementary strengths of visible and infrared imagery to improve scene understanding; however, effectively integrating these heterogeneous modalities at varying levels of feature abstraction remains an open problem. In this paper, we propose a multi-modal fusion architecture built upon dual ConvNeXt V2 backbones that employs stage-wise, modality-adaptive fusion strategies. For early-stage features, we introduce a Frequency-Based Fusion Module that decomposes infrared features into low- and high-frequency components via Gaussian filtering, applies dual-branch spatial attention to selectively emphasize thermal patterns and fine-grained boundaries, and integrates them with RGB features through a confidence-gated residual mechanism. For late-stage features, we design a semantic fusion module with cross-modal attention and multi-scale depthwise convolutions to capture semantic correspondences across modalities. The fused features are decoded via a PANet-style bidirectional decoder with deep supervision. Experiments on MFNet and PST900 demonstrate that our lightest variant achieves 61.73% and 86.24% mIoU, respectively, with only 35.43M parameters, outperforming recent methods while using substantially fewer parameters and lower computational cost. Code is available at https://github.com/ismailemrecntz/VISIBLE-INFRARED-SENSOR-FUSION

Recent advances in semantic segmentation rely heavily on attention-based and transformer-style architectures that, while accurate, introduce considerable architectural complexity and computational cost. This paper asks whether a compact CNN-based segmentation head can remain competitive by adaptively selecting useful receptive-field evidence. We propose ATV-Net, an Adaptive Triple-View Network that attaches a lightweight head to a conventional backbone. The head organizes three complementary views -- point-wise, neighborhood-level, and enlarged context -- and fuses them through an Adaptive Decision Gate that generates image-dependent weights from global feature statistics. This allows the model to emphasize different receptive-field responses according to scene content, without dense attention or multi-scale aggregation. Experiments on Cityscapes and Pascal VOC 2012 show that ATV-Net achieves 80.31% mIoU on Cityscapes with ResNet-101 and 80.90% with ConvNeXt-Tiny, and 86.7% and 88.5% mIoU on Pascal VOC 2012, respectively, while requiring fewer GFLOPs than representative context-aggregation and attention-based heads. The results indicate that adaptive receptive-field selection remains a practical and effective design choice for CNN-based semantic segmentation.

Semi-supervised learning has become a dominant paradigm for reducing annotation costs. However, we argue that the current progress is clouded by a twofold overconfidence problem. Algorithmically, mainstream pseudo-labeling frameworks often conflate prediction confidence with uncertainty, leading to severe confirmation bias. Strategically, since multiple benchmark datasets lack dedicated validation sets, some studies use the test set for validation as well, leading to inflated performance estimates. Subsequent methods, compelled to employ the same strategy to surpass reported SOTA, trigger an arms race of overfitting. This raises concerns that the impressive numerical gains in the community may reflect overfitting rather than genuine progress. Thus, we propose a tri-space calibrated segmentation framework founded on a principled dual-axis reliability assessment engine. It explicitly decouples confidence from uncertainty and uses this signal to detect and correct confirmation bias across feature, probability, and image spaces in a collaborative manner. Across three benchmark datasets, TCSeg consistently delivers strong performance under existing evaluation protocols. More importantly, we advocate that the community report final-checkpoint results under multiple-run protocols, thereby establishing more rigorous benchmarks with a more realistic perspective. Code will be available: github.com/DirkLiii/TCSeg.

Image enhancement plays a crucial role in infant fingerprint matching, as child-specific characteristics such as smaller finger dimensions and thinner ridge structures often degrade image quality during acquisition. To address these limitations, enrollment typically depends on specialized highresolution scanners, which most existing enhancement methods are not designed to support. Consequently, identification rates for children remain significantly lower than those achieved with adult fingerprints. This study introduces Recursive Class Connectivity Classification (R3C), a novel framework that iteratively refines binary segmentation outputs from existing enhancement methods by extending ridge structures. R3C does not require modifications to the underlying classifier and operates without training data, which is not currently available for infant fingerprints. Instead, the method improves segmentation by repeatedly feeding the classified image back into the classification process, while combining each intermediate segmentation with the original input image. Experiments conducted on three fingerprint datasets using four different enhancement classifiers show that R3C can increase the True Acceptance Rate (TAR) by up to 4% for children and over 40% for newborns, compared to using the enhancement methods alone. A qualitative analysis further demonstrates that R3C reconnects fragmented ridge patterns, improving the visual quality of segmentation. Because it functions independently of the enhancement method used, R3C provides a flexible and broadly applicable solution for improving binary segmentation.

Dataset distillation (DD) aims to compress large-scale datasets into compact synthetic sets while preserving training efficacy. However, existing studies mainly focus on image classification, leaving dense prediction tasks such as semantic segmentation largely underexplored. In this work, we identify three key challenges for segmentation DD: (i) long-tailed class imbalance, (ii) the need for strict pixel-wise alignment between images and dense labels, and (iii) the high computational cost of optimizing high-resolution data with complex models. To address these challenges, we propose D3S2, a Diffusion-guided Dataset Distillation framework for Semantic Segmentation. Our method adopts a two-stage design. In Class-Balanced Mask Selection, we construct a representative mask set via a greedy strategy that prioritizes underrepresented classes. In Diffusion-Guided Image Synthesis, we employ a pretrained layout-to-image diffusion model to generate images conditioned on the selected masks, naturally ensuring spatial alignment. To further enhance the training utility of synthesized data, we introduce guided diffusion sampling with two complementary objectives: a segmentation-consistency loss for pixel-level alignment, and a class-wise feature matching loss for aligning per-class feature statistics across layers. Extensive experiments demonstrate the superiority of D3S2. Notably, at an extremely compression rate of 1%, our method achieves 24.99% and 35.49% mIoU on ADE20K and COCO-Stuff with Mask2Former (Swin-S), outperforming random selection by 9.34% and 5.70%, respectively.

Vision Transformers (ViTs) can learn strong image-level representations while their patch representations become less effective for dense prediction during prolonged training. We revisit this dense degradation phenomenon and argue that it is not fully explained by high-norm artifacts alone. Instead, we characterize \emph{semantic diffusion}: an optimization shortcut in which global semantic information spreads through patch tokens beyond what is locally justified. Our analysis shows that dense representation quality is not captured by locality alone: shallow features can remain better aligned with foreground regions yet underperform deeper features, and \texttt{[CLS]} features remain complementary for dense prediction. These observations suggest that the goal should not be to remove global context, but to make token interactions more selective. We therefore study sparse attention as a minimal intervention, replacing softmax attention with entmax-1.5 while preserving global token connectivity. On DINOv1 ViT-S/16 trained for 200 epochs on ImageNet-1K, this change preserves ImageNet linear probing accuracy and substantially improves semantic segmentation performance: VOC mIoU increases from 42.80 to 48.78, ADE20K from 19.85 to 21.97, and Cityscapes from 36.79 to 37.87. These results suggest that selective token mixing is a simple and effective bias for improving dense ViT representations.

Tracking tumor lesions across serial CT scans is essential for oncological response assessment. Existing automated methods face a fundamental trade-off: end-to-end trackers achieve high automation but offer no opportunity to correct silent tracking failures, while decoupled registration-segmentation pipelines permit user verification yet discard the lesion's prior appearance, limiting accuracy in ambiguous cases. In this work, we propose a Verified Tracking paradigm: a clinician verifies a registration-proposed prompt, which the model leverages alongside the baseline lesion appearance to resolve segmentation ambiguities. We present a unified framework combining early spatial prompt fusion with latent temporal difference weighting for longitudinally-informed segmentation. To address data scarcity, we leverage large-scale synthetic pretraining, proving essential for exploiting longitudinal context, improving performance by up to 4.5 Dice points over training from scratch. Our approach secured first place in the MICCAI autoPET IV challenge. We further curate and release PanTrack, a new longitudinal pancreatic cancer benchmark, to assess out-of-distribution generalization. Experiments show that our model outperforms prior work in both fully automatic and the proposed verified tracking setting offering a clinically safe middle ground between automation and control. Code, model and dataset will be released at https://github.com/MIC-DKFZ/LongiSeg

Previous detection studies have shown that LLMs cannot be effectively used as detectors, but these studies have not addressed modern Chinese poetry. Moreover, no relevant research has explored the performance of LLMs in detecting modern Chinese poetry. This paper evaluates and enhances the performance of LLMs as detectors for modern Chinese poetry, and proposes an image-semantic guided poetry detection method. Compared with traditional detection approaches, our method innovatively incorporates images that reflect the content of the poetry. Through example-driven approaches, our method effectively integrates information such as meaning, imagery, and feeling from the image, then forms a complementary judgment with the poem text. Experimental results demonstrate that the LLM detectors based on our method outperform baseline detectors based on plain text, and even surpass the best-performing traditional detector, RoBERTa. The Gemini detector using our method achieves a Macro-F1 score of 85.65%, reaching the state-of-the-art level. The performance improvements of different LLM detectors on multiple LLMs-generated data prove the effectiveness of our method.

Grounding radiology report descriptions to 3D CT volumes is essential for verifiable clinical interpretation, yet remains challenging due to the semantic-spatial gap between free-text narratives and volumetric anatomy. Existing report-assisted and vision-language grounding methods typically rely on phrase-level alignment or dense pixel supervision, resulting in limited lesion-wise correspondence and suboptimal localization accuracy. We propose GLeVE, a graph-guided lesion grounding framework with anatomical prior verification and octree-based autoregressive refinement. GLeVE treats each lesion description as an atomic semantic unit and encodes organ attribution, attributes, and inter-lesion relations through relation-aware graph reasoning to produce discriminative lesion-wise queries. Anatomy-aware proposal generation with region-level verification enforces one-to-one text-lesion alignment, while hierarchical octree refinement progressively improves boundary delineation. Experiments on AbdomenAtlas 3.0 demonstrate consistent gains over classical multimodal foundation models and report-supervised baselines in both segmentation accuracy and lesion-level localization.

Fine-grained semantic segmentation requires both precise localization and discrimination between visually similar classes. In FungiTastic, this problem is further complicated by a long-tailed distribution and strong variation in image acquisition conditions. We propose a training-free two-stage framework that decouples segmentation from classification. SAM3 first produces class-agnostic mushroom masks using macro-taxonomic prompts, and DINOv3 then assigns fine-grained labels through prototype matching in the embedding space. To improve this stage, we apply a simple transformation of the DINOv3 feature space that improves prototype-based classification. Compared with class-specific prompting, our approach is more scalable and keeps the segmentation cost low. We report results from one-shot to few-hundred-shot regimes, providing, to the best of our knowledge, the first baseline for fine-grained semantic segmentation in low-data settings.

Visual Question Answering (VQA) holds great promise for clinical support, particularly in ophthalmology, where retinal fundus photography is essential for diagnosis. However, ophthalmic VQA benchmarks primarily emphasize answer accuracy, neglecting the explicit visual evidence necessary for clinical interpretability. In this work, we introduce FundusGround, a new benchmark for clinically interpretable ophthalmic VQA with spatially-grounded lesion evidence. Specifically, we propose a three-stage pipeline that collects 10,719 fundus images with 15,595 image-level meticulously annotated lesions. To ensure anatomical consistency and clinical validity, all lesions are spatially localized using the Early Treatment Diabetic Retinopathy Study (ETDRS) grid, enabling standardized mapping to nine clinically meaningful retinal regions. Built upon this structured lesion evidence, 72,706 questions are then generated spanning four formats: open-ended, closed-ended, single-choice, and multiple-choice. We further benchmark multiple general- and medical- large vision-language models using dual metrics for answer accuracy and lesion-level reasoning. The experiments demonstrate that incorporating lesion-level visual evidence consistently improves model performance and transparency, highlighting the necessity of explicit spatial grounding for reliable and explainable ophthalmic VQA.

Accurate segmentation of hepatic and portal vessels in contrast-enhanced computed tomography angiography (CTA) remains challenging due to complex vascular topology, peripheral visibility limitations, and acquisition-induced ambiguities. While existing public datasets offer valuable benchmarks, few include clinically realistic annotation constraints. We introduce VEELA (Vessel Extraction and Extrication for Liver Analysis), a rigorously curated liver vessel dataset derived from 40 CTA scans inherited from the CHAOS grand-challenge cohort. All vessels were manually delineated slice-by-slice under multi-expert consensus, using a strict visibility-driven annotation policy and avoiding anatomically inferred interpolation. This design explicitly captures anatomical variability and imaging-related uncertainty. As a continuation of the CHAOS challenge, VEELA enables reproducible cross-benchmark evaluation while extending the scope to fine-grained hepatic and portal vessel segmentation. We further establish a standardized benchmarking framework and analyze complementary evaluation metrics, including topology-aware (clDice), overlap-based (IoU), boundary-sensitive (NSD), and geometry-aware (area, length) measures. Our results demonstrate that different metrics capture distinct aspects of vascular integrity, underscoring the necessity of multi-perspective evaluation for clinically meaningful vessel segmentation. VEELA is publicly released to facilitate reproducible research and support the development of robust vascular segmentation methods. Researchers can access the evaluation metrics, dataset, and submission platform at https://www.synapse.org/Synapse:syn65471967.

Purpose: To assess whether breast lesion segmentation can be learned directly from acquired MRI k-space, and whether doing so improves robustness when data are accelerated or noisy. Materials and Methods: This retrospective study used public breast dynamic contrast-enhanced MRI (DCE-MRI) datasets with acquired and synthetic k-space, together with a within-dataset synthetic control. We compared four 3D U-Net variants: a hybrid k-space-to-image model, a native k-space model, and magnitude and complex image-space baselines. Models were evaluated under increasing undersampling and added complex Gaussian k-space noise. The primary outcome was patient-level Dice similarity coefficient under cross-validation, with the hybrid model prespecified as the main comparison against the magnitude image-space baseline. Results: At full sampling, the hybrid and image-space models performed similarly. As acceleration increased, the hybrid model retained substantially more segmentation accuracy and significantly outperformed the magnitude image-space baseline across moderate to high undersampling levels. The same pattern was observed when noise was added directly to k-space: the hybrid model degraded more slowly, whereas the image-space baseline failed under heavier noise. This advantage was reproduced in the within-dataset synthetic control. Feature analysis suggested that the k-space stage and image-space stage played complementary roles, with frequency-domain filtering concentrated before image-domain lesion localization. Conclusion: K-space-aware deep learning improves the robustness of breast lesion segmentation under MRI undersampling and k-space noise, while matching image-space methods at full sampling.

This report presents our solution for the WeatherProof Dataset Challenge, namely CVPR 2026 8th UG2+ Challenge Track 2: Semantic Segmentation in Adverse Weather. For the semantic segmentation task under adverse weather conditions, we propose a semi-supervised segmentation pipeline. Our method is trained exclusively on the WeatherProof dataset, without using any additional external data. Specifically, we adopt UniMatch V2 as the baseline model and treat all degraded-weather images as unlabeled data for semi-supervised training, thereby fully exploiting the data distribution provided by the challenge. During inference, we further apply test-time augmentation to improve the robustness and segmentation accuracy of the final predictions. The code is publicly available at: https://github.com/ylb888/weatherproof-challenge-unimatchv2.

Biomedical image segmentation is a critical task in medical diagnosis and treatment planning, enabling precise delineation of anatomical structures and pathological regions. Despite significant advancements, challenges persist due to the inherent variability, noise, and complex morphology present in diverse medical imaging modalities. This paper introduces ConvNeXt-FD, a novel deep learning architecture for robust biomedical image segmentation, built upon a U-Net-like encoder-decoder framework leveraging the powerful ConvNeXt backbone. Our approach integrates a hybrid loss function combining the Dice coefficient with a boundary-aware regularization term inspired by a differentiable formulation of Fractal Dimension, designed to enhance the model's sensitivity to object boundaries and shape fidelity. We rigorously evaluate ConvNeXt-FD across six distinct biomedical datasets: BUSI (Breast Ultrasound Images), DDTI (Thyroid Ultrasound Images), FluoCells (Fluorescent Cell Images), IDRiD (Diabetic Retinopathy Images for Optic Disc Segmentation), ISIC2018 (Skin Lesion Images), and MoNuSeg (Nuclei Segmentation). Experimental results demonstrate that ConvNeXt-FD, particularly when initialized with ImageNet pre-trained weights, achieves competitive and often superior performance compared to existing state-of-the-art methods across various metrics, including Dice, Jaccard, Accuracy, Sensitivity, Specificity, and False Positive Rate. The integration of ConvNeXt as a strong encoder, coupled with the boundary-aware regularization, proves effective in capturing both high-level semantic features and fine-grained boundary details, leading to more accurate and reliable segmentations in challenging biomedical contexts.

The synergistic interpretation of anatomical information from computed tomography (CT) and metabolic information from positron emission tomography (PET) is important to oncologic imaging. However, existing deep learning methods for PET/CT remain largely task-specific, are often trained on single-center cohorts, or adopt dual-branch fusion schemes that delay cross-modal interaction and underutilize early spatial correspondence between PET and CT. To address these limitations, we present an open-source, multi-center, whole-body FDG PET/CT foundation model utilizing 4,997 harmonized scans from four public datasets. Our framework employs hierarchical UNet-shaped backbones with early channel-wise concatenation, enabling anatomical and metabolic features to interact from the first embedding layer onward. We further introduce a masked autoencoding objective based on zero-mean imputation, combined with a weighted global reconstruction loss. This design avoids non-physical intensity discontinuities at masked-region boundaries that arise from learnable mask tokens. On downstream AutoPET lesion segmentation, the proposed models demonstrate strong label efficiency: with only 10% of the labeled training data, they achieve performance comparable to models trained from scratch on the full dataset. Under extreme 5-shot linear probing, joint PET/CT pretraining also achieves higher Dice scores than separated-modality pretraining. This multi-center foundation model demonstrates label efficiency and cross-modality representation learning for PET/CT tumor segmentation. It provides a robust, open-source basis for advancing automated oncologic imaging, significantly reducing the need for large-scale manual annotations in clinical practice.

When the blood supply to the brain is obstructed by a clot, oxygen delivery to brain tissues becomes insufficient, leading to cellular necrosis. In healthcare settings, accurately identifying and delineating ischemic lesion boundaries is essential for treatment and surgical planning. However, ischemic stroke lesions vary widely in shape, size, and location, and in grayscale MRI modalities such as T1W they may resemble surrounding brain structures. This makes lesion detection and segmentation a challenging task for clinicians. This study introduces a novel VRU-Net architecture, derived from visual features, residual connections, and a U-shaped network, for detecting and segmenting ischemic stroke lesions in 3D magnetic resonance imaging scans. The proposed method first uses a modified VGG model to identify ischemic stroke in separate 2D slices. Then, a U-shaped segmentation model with residual blocks segments the lesion in each slice. This procedure is applied independently to the axial, sagittal, and coronal planes, and the final output is generated by aggregating the three segmentation results. To improve both performance and processing speed, a high-performance classifier is applied before the segmentation model in a sequential framework. This strategy reduces unnecessary segmentation of non-lesion slices and improves overall accuracy. In addition, decomposing 3D images into 2D slices reduces model complexity while allowing information from three anatomical planes to support more accurate lesion localization. The proposed model is trained on the Anatomical Tracings of Lesions After Stroke dataset and outperforms state-of-the-art models in terms of accuracy and Dice coefficient. Moreover, the segmentation output provides feedback that helps the classification model reduce false-positive predictions.

LiDAR semantic segmentation is a core perception capability for autonomous vehicles and mobile robots. However, safe operation also depends on knowing when predictions are unreliable. Existing approaches typically rely on softmax confidence, which is often miscalibrated and overconfident, while stronger uncertainty estimates from Monte Carlo dropout or ensembles are often computationally expensive for real-time use. To this end, we introduce a novel, architecture-agnostic uncertainty-aware Adapter Head. It decomposes the prediction into a Preference Head for class ranking and a Strength Head that refines uncertainty assessment, thereby enabling a principled construction of evidential Dirichlet representations. Building on this design, we propose our inverse-vacuity self-calibration objective (Invascal), which directly supervises the strength signal to produce reliable and well-calibrated uncertainty estimates while preventing runaway evidence growth. We evaluate our framework across multiple LiDAR datasets and backbone architectures. We compare against deterministic training, Monte Carlo dropout and ensembles, and prior evidential methods. Our approach consistently improves uncertainty calibration over traditional deterministic methods with minimal computational overhead. At the same time, it preserves competitive segmentation accuracy, where prior evidential methods often suffer performance degradation.

Road segmentation is a fundamental perception task for autonomous driving and mobile robotics, where both appearance and geometric cues must be processed under edge-computing constraints. Existing multi-modal approaches often improve accuracy with large encoders or expensive global interaction, which limits their use on embedded platforms. We present \textbf{LiteViLNet}, a lightweight RGB-geometry fusion network that combines a MobileNetV3 RGB encoder with a 0.12M-parameter depth-wise-separable geometry encoder. A multi-scale feature fusion module performs modality-specific enhancement, global-query cross-modal interaction, and adaptive gating, while a depth-wise large-kernel bridge enlarges the contextual support of the deepest representation with low overhead. The resulting U-Net-style decoder uses deep supervision only during training. On the KITTI Road benchmark, the 14.04M-parameter full model obtains $97.23\pm0.15\%$ MaxF. On the held-out ORFD test set under the released OFF-Net evaluation protocol, the full model achieves $96.74\pm0.09\%$ F-score and $93.68\pm0.18\%$ IoU. On a Jetson Orin NX, model-only PyTorch FP16 inference reaches $22.18\pm0.21$ FPS; a separate TensorRT FP16 measurement reaches $68.73\pm0.06$ FPS on the Jetson. Camera-depth adaptations and perception-and-control demonstrations on three heterogeneous robot platforms further illustrate the portability of the dual-stream design.

The demand for unmanned aerial vehicle (UAV)-based image acquisition and analysis has surged, with UAVs increasingly utilized for semantic segmentation tasks. To meet the real-time analysis requirements of UAV remote sensing missions, performing onboard computation and making decisions based on the results is a natural approach. However, deploying semantic segmentation on resource-constrained UAV platforms presents two significant challenges: 1) hardware constraints limit the ability of UAVs to perform real-time semantic segmentation, and 2) environmental variations during flight cause data distribution shifts, deviating from the original training data. To address these issues, this paper introduces SkySeg, a heterogeneous multi-UAV air-air cooperation framework that integrates computer vision and flight pattern to enable onboard semantic segmentation using low-cost sensors. SkySeg employs an efficient information fusion inference method, combining low-definition, wide-area images with high-definition, focused-area images. Additionally, it incorporates a cross-device test-time adaptation (TTA) strategy to enhance segmentation performance in dynamic environments by collaboratively addressing distribution shifts of test data streams across UAVs. Experimental results demonstrate that our SkySeg framework accelerates inference latency by approximately 3.6x, improves onboard segmentation accuracy by 5.91%, and achieves a 10.91% average accuracy gain in the wild.

In recent years, there has been a notable increase in the level of attention that is given to algorithms based on deep learning in the context of medical image segmentation. Nevertheless, the reliability of the field has been hindered due to the absence of a standardized methodology for performance analysis and the utilization of different datasets in previous research. The primary objective of the research is to comprehensively evaluate contemporary segmentation frameworks combined with state-of-the-art pre-trained backbones in order to accurately predict COVID-19 lesions in CT images. Moreover, this evaluation can serve as a point of reference for the segmentation of images in various other imaging scenarios. In order to accomplish this, we integrate four distinct deep learning architectures, namely Unet, PSPNet, Linknet, and FPN, with six pre-trained encoders, including VGG 19, DenseNet 121, Inception ResNet V2, MobileNet V2, SeresNet 101, and EfficientNet B0. This approach enables the development of diverse testing architectures. In the context of image segmentation, our research encompassed both binary and multi-class experimentation. The findings derived from our analysis of three distinct COVID-19 CT segmentation datasets indicate that deep learning architectures yield precise and efficient segmentation outcomes. Significantly, a maximum F1-Score of 98% was attained for binary class segmentation, while multi-class segmentation yielded F1-Scores of 75% and 77% across two separate datasets. The utilization of artificial intelligence and deep learning enhances the diagnostic process for pandemic diseases across multiple dimensions.

Class imbalance is a fundamental challenge in medical image segmentation, where frequent classes typically dominate training at the expense of rare classes. Loss-based approaches mitigate imbalance by reweighting the per-pixel loss within the batch, while sampling strategies control which images enter the batch. Yet neither explicitly controls which classes appear within the batch, leaving rare-class exposure only partially rebalanced. In this work, we adopt episodic sampling from few-shot learning to promote class-balanced batch construction in a fully supervised setting. We decouple episodic sampling from its conventional metric-learning context and evaluate it in body composition segmentation in CT. We compare episodic sampling against random and weighted sampling on nine muscle and adipose tissues, derived from 210 scans of the public SAROS dataset. Training is performed under full- and low-data regimes, with additional comparisons under matched training iteration budgets. Under full-data training, all three strategies performed comparably (mean Dice 0.882 for episodic, 0.878 for random and weighted). Under low-data training, episodic sampling outperformed random and weighted (0.787 vs. 0.758 and 0.762), driven by a 12-fold difference in training iterations. Under matched training budgets, random and weighted overfit earlier, while episodic improved for approximately three times more iterations before plateauing. Our findings identify the training iteration budget as under-recognized confound in sampling strategies, motivating iteration-aware evaluation protocols for small datasets. Furthermore, the residual advantage of episodic sampling is consistent with an implicit regularization effect of class-balanced batches, offering a low-cost, model-agnostic strategy for class-imbalanced medical image segmentation. Code is available at https://github.com/iasonsky/episodic-sampling.

Chronic wounds such as diabetic foot ulcers and pressure injuries require accurate tissue-level assessment to guide treatment planning and monitor healing progression. While deep learning methods have advanced automated wound analysis, most existing approaches focus on binary segmentation and inadequately model heterogeneous tissue composition due to high intra-class variability and limited annotated data. Multi-class wound tissue segmentation, therefore, remains a challenging and clinically relevant problem. We propose WoundFormer, a transformer-based framework that enhances hierarchical spatial feature fusion for multi-class wound tissue segmentation. Specifically, we replace the standard SegFormer decoder with a spatially-preserving multi-scale aggregation head that maintains feature topology during cross-scale integration and strengthens contextual interactions through convolutional fusion. This design improves boundary localization and discrimination between visually similar tissue categories while preserving transformer efficiency. We evaluate WoundFormer on the WoundTissueSeg dataset (147 images, six tissue classes) and a second benchmark (DFUTissue dataset). The proposed method achieves an overall Dice score of 81.9%, outperforming strong CNN- and transformer-based baselines by up to 4.3 Dice points on the WoundTissueSeg benchmark, with consistent improvements across minority tissue classes. These results indicate that explicit modeling of hierarchical spatial interactions enhances transformer representations for heterogeneous wound tissue segmentation and supports more reliable quantitative wound assessment.

Medical image segmentation faces a fundamental challenge in continual learning: data arrives sequentially from heterogeneous sources, yet effective continual learning requires discovering which tasks share sufficient structure to benefit from joint learning. Existing methods either apply uniform constraints across all tasks, causing catastrophic forgetting when tasks conflict, or require predefined task groupings that cannot anticipate future task diversity. We introduce MedCRP-CL, a framework that performs online task structure discovery and structure-aware continual learning. Leveraging the Chinese Restaurant Process (CRP), our method dynamically infers task groupings from clinical text prompts as tasks arrive, without requiring predefined cluster counts or access to future tasks. We term these discovered groupings semantic modalities, as they capture finer-grained structure than physical imaging modalities by integrating anatomical region and pathological context. Guided by this discovered structure, we maintain semantic modality-specific LoRA adapters regularized by intra-modality EWC, ensuring parameter isolation across dissimilar task groups while facilitating knowledge transfer within similar ones. The framework is also replay-free, storing only aggregate statistics rather than raw patient data. Experiments on 16 medical segmentation tasks across four imaging modalities demonstrate that MedCRP-CL achieves 73.3% Dice score with only 4.1% forgetting, outperforming the best baseline by 8.0% while requiring 6$\times$ fewer parameters. Code is available at https://github.com/zygao930/MedCRP-CL.

Segmentation has become easy when the concept is known, requiring retrieval of a learned visual grounding from text. It remains hard for open ad-hoc concepts, where the grounding may not exist as one learned mask and must often be constructed from image evidence through parts, relations, exclusions, and collections. We propose a Vision-guided Ad-hoc Segmentation Agent (VASA), the first vision harnessing agent for open ad-hoc segmentation. VASA is training-free and couples a VLM agent, a segmentation foundation model, and a visually grounded workflow. Rather than revising text prompts alone, VASA uses a persistent working mask to reason, construct, and validate a solution. It plans visual operations, invokes segmentation tools, inspects results, edits the mask, and recovers from errors. We construct PARS, a new benchmark that turns part-level labels in PartImageNet into open ad-hoc concepts through long-form definition queries. On PARS, VASA outperforms open-vocabulary, reasoning-based, and agentic baselines, surpassing SAM3 Agent by 14-25%. On RefCOCOm, a standard multi-granularity referring segmentation benchmark, VASA improves over SAM3 Agent by 5-9% and over other agentic baselines by up to 20%. These results validate agentic visual construction for open ad-hoc segmentation. Our work points to a path for AI agents beyond wrapping foundation models as tools: Programming them with task knowledge, VLM behavior, visual routines, working memory, and failure-aware workflows.

Convexity is a fundamental geometric prior that underlies many natural and man-made structures, yet remains challenging to impose effectively in end-to-end trainable segmentation networks. We revisit convexity from a functional perspective and propose a unified, threshold-free convexity prior based on the quasi-concavity of the network's output mask function u. Instead of constraining a single binary segmentation, we require all super-level sets of u to be convex, transforming global shape constraints into local, differentiable inequalities on u and its derivatives. From this principle, we derive zero, first, and second-order characterizations, yielding respectively a local midpoint convexification algorithm, a gradient-based condition linked to supporting hyperplanes, and a sufficient second-order inequality expressed as a quadratic form on the tangent plane. The first and second-order formulations produce a compact convolutional loss that can be densely applied across the image without thresholding. Our quasi-concavity losses integrate seamlessly with modern segmentation networks via the proposed convex gradient projection module (CGPM). They consistently enforce convexity and improve shape regularity across multiple datasets, outperforming networks tailored for retinal segmentation and surpassing previous shape-aware methods. Remarkably, our analysis unifies a wide spectrum of previous convex shape models, from discrete 1-0-1 line constraints and graph-cuts convexity formulations to curvature or signed distance Laplacian based level-set priors, within a single continuous and differentiable framework.

Medical image segmentation is more clinically valuable when it supports diagnosis rather than merely producing lesion masks. However, diagnostically relevant lesion cues are often subtle and localized, while existing models may be distracted by background tissues, acoustic artifacts, and irrelevant visual correlations. To address this problem, we propose Rad-VLSM, a two-stage cross-modal framework for semantics-assisted lesion focusing, robust segmentation, and visually grounded diagnosis. In the first stage, a BLIP-2-based vision-language alignment module identifies lesion-related candidate regions under semantic guidance and converts them into box prompts. In the second stage, these prompts are fed into a SAM-based multitask network, where a multi-candidate region aggregation strategy improves prompt stability and guides lesion segmentation. The predicted masks are then used as spatial priors for diagnosis, and a visual-radiomics fusion head integrates lesion-aware visual features with selected radiomics descriptors. By using semantic information for localization rather than direct prediction, Rad-VLSM reduces text-to-diagnosis dependence and grounds diagnosis in lesion-level evidence. Experiments on a private clinical breast ultrasound dataset and public benchmarks show that Rad-VLSM achieves strong segmentation and diagnostic performance with favorable generalization.

Few-Shot Medical Image Segmentation (FSMIS) aims to delineate novel anatomical targets from one or a few annotated support images, addressing the annotation scarcity in medical imaging. Notwithstanding recent advancements, current prototype-based methods are bottlenecked by two coupled limitations: 1) cue entanglement, where a single spatial-domain prototype is forced to summarise organ silhouette, parenchymal texture and boundary appearance simultaneously, so any support-query mismatch on one cue propagates indiscriminately to the others; and 2) topology-blind matching, where cosine similarity measures distance in the ambient Euclidean space and ignores the connectivity of the underlying feature manifold, causing fragmented activations inside low-contrast organs and leakage into neighbouring tissues. To this end, we propose Spectral-Geodesic Prototype Network (SGP-Net), built around a Spectral-Geodesic Prototype Module with two coupled components. A Spectral Prototype Bank (SPB) decomposes support and query features into low-, mid- and high-frequency bands via learnable radial Fourier filters, yielding three disentangled prototypes per class that separately encode shape, texture and boundary cues. A Geodesic Matcher (GM) then replaces cosine similarity with a differentiable heat-diffusion approximation of geodesic distance, propagating matching signals along a feature affinity graph so that on-manifold pixels accumulate consistent responses while off-manifold look-alikes are suppressed. Experiments on three public FSMIS benchmarks demonstrate that SGP-Net achieves competitive performance against recent state-of-the-art methods.

CNN- and Transformer-based architectures have achieved strong performance in medical image segmentation, but CNNs are limited in modeling long-range dependencies, while Transformers often suffer from quadratic computational and memory complexity. State space models, especially Mamba-based networks, offer an efficient alternative with linear sequence complexity. However, existing Mamba segmentation models still face two limitations: pixel-wise directional scanning can disrupt local 2D spatial structure, and simple summation-based fusion of scan directions cannot adapt well to diverse object sizes, shapes, and boundaries. To address these issues, we propose \textit{Patch-MoE Mamba}, a patch-ordered mixture-of-experts state space architecture for medical image segmentation. It introduces a hierarchical patch-ordered scanning mechanism that preserves local spatial neighborhoods while capturing multi-scale context, and an MoE-based directional fusion module that adaptively combines multiple Mamba scanner outputs using four directional experts, a learnable concatenation expert, and residual directional aggregation. Experiments on five public polyp segmentation benchmarks and the ISIC 2017/2018 skin lesion segmentation datasets demonstrate the effectiveness and generality of Patch-MoE Mamba.

We investigate the potential of invariant and equivariant semi-supervised learning for addressing the challenges of training multi-task models on partially labeled datasets with differently structured output tasks. Specifically, we use the popular FixMatch method for invariant semi-supervised learning and its equivariant extension Dense FixMatch. We evaluate their performance on the Cityscapes and BDD100K datasets in the context of the prevalent object detection and semantic segmentation tasks in computer vision. We consider varying sizes of the subsets annotated for each task and different overlaps among them. Our results for both invariant and equivariant semi-supervised learning outperform supervised baselines in most situations, with the most significant improvements observed when fewer labeled samples are available for a task and generally better results for the latter approach. Our study suggests that invariant/equivariant learning is a promising general direction for multi-task learning from limited labeled data.

The release of public 3D medical image segmentation (MIS) datasets accelerates clinical research but simultaneously heightens risks of unauthorized AI model training. While Unlearnable Examples (UE) offer protection by injecting imperceptible perturbations to prevent effective model learning, existing methods primarily target 2D scenarios. They neglect the volumetric spatial correlations and inter-slice anatomical consistency inherent in 3D medical volumes, which serve as critical learning priors for 3D segmentation networks. To bridge this gap, we propose VoxShield, a UE framework that explicitly targets the volumetric inductive biases of 3D networks. Our core insight is that by systematically dismantling the cross-slice continuity that 3D architectures rely on, we can fundamentally impair their spatial aggregation process. Specifically, we introduce an Inter-Slice Frequency Consistency Disruption mechanism that maximizes the spectral divergence between adjacent slices, injecting structural incoherence along the $z$-axis. Complementing this structural attack, a Semantic Prediction Disruption module is incorporated. By maximizing the $\ell_1$ divergence between clean and perturbed logits, it forces the injected noise to penetrate the entire network and corrupt the final semantic mapping. Experiments on BraTS19 and FLARE21 demonstrate that VoxShield successfully degrades 3D segmentation performance, reducing the DSC from 80.0% to near 0.0% and from 88.6% to 6.8%, respectively. All protections are achieved with minimal perturbation ($ε=4/255$) to preserve high visual fidelity. The code is available at https://github.com/KK266299/VoxShield.

Accurate segmentation and statistical shape modeling of hand anatomy have significant implications for medical diagnostics, ergonomics, and biomechanics. This study proposes an AI-assisted reconstruction pipeline for segmenting and analyzing hand anatomy from 1,271 elbow-to-hand (e2h-CT) computed tomography scans. A Pix2Pix-based conditional generative adversarial network is first employed to remove plaster cast and background artifacts from CT volumes. The cleaned scans are then processed in 3D Slicer to extract skin and bone masks, which are converted into closed-surface mesh models. Segmented bone meshes are used to construct skeletal representations, enabling implicit skinning to align all hand models into a standardized anatomical configuration. Subsequently, non-rigid registration is performed on the hand skin surfaces using the Geodesic Based Coherent Point Drift++ (GBCPD++) algorithm to establish point-wise correspondence across subjects. Principal Component Analysis (PCA) is then applied to the registered models to quantify anatomical shape variability. The Pix2Pix preprocessing stage achieved a Dice coefficient of 0.9856 and an IoU of 0.9720 on the held-out test set. Statistical modeling was performed on a subset of 90 scans in which the fingers were fully visible and anatomically separated. The resulting statistical shape distributions demonstrate strong agreement with the U.S. Army Anthropometric Survey (ANSUR II), supporting the anatomical validity of the reconstructed models. The proposed methodology demonstrates significant potential for advancing biomechanical modeling, ergonomic optimization, prosthetic design, and precision medical diagnostics.

Automated segmentation of liver lesions on non-contrast computed tomography (NCCT) is clinically important but fundamentally challenging, particularly in low-resource settings across Africa and Asia where contrast agents are frequently unavailable. Progress has been limited by the absence of annotated NCCT benchmarks. Here we describe the TriALS challenge for automated liver lesion segmentation under contrast-limited conditions, supported by a multi-centre dataset of 150 cases with four-phase CT acquisitions (600 volumes) from Egyptian and Chinese institutions. Algorithms were evaluated on 70 cases from three institutions, including an independent external cohort. The top-performing method achieved a mean venous-phase Dice of 0.754, consistent with human-level performance, yet dropped to 0.57 on NCCT. On external validation, the leading method outperformed off-the-shelf models by up to 28% in Dice on NCCT. Algorithm performance was most strongly predicted by training data scale and pre-training strategy. A cross-year comparison exposed a persistent perceptual barrier on NCCT that scaling pre-training alone cannot overcome. Data, annotations, and code are available at https://github.com/xmed-lab/TriALS.

Medical referring image segmentation (MRIS) requires pixel-level masks aligned with textual descriptions of anatomical locations, making annotation costly in low-label regimes. Semi-supervised learning (SSL) can mitigate this burden by leveraging unlabeled data, but its success hinges on maintaining reliable image-text alignment under perturbations. Most existing SSL-based referred segmentation methods use either independent or simplistic multi-modal perturbations (e.g., left-right flips), without fully addressing cross-modal alignment under strong augmentation, while CutMix, highly effective in single-modal SSL, remains underexplored in multi-modal settings due to its tendency to disrupt image-text coherence. We propose Semi-MedRef, a teacher-student SSL framework designed to explicitly maintain consistency between medical images and positional language through three alignment-preserving components: T-PatchMix, a cross-modal CutMix-style augmentation that synchronizes patch mixing with referring expressions via position-constrained and probability-driven rules; PosAug, a position-aware text augmentation that masks or fuzzes anatomical phrases; and ITCL, a position-guided image-text contrastive learning module, which leverages positional pseudo-labels to construct soft anatomical positives and strengthen medically grounded cross-modal alignment. Experiments on QaTa-COV19 and MosMedData+ demonstrate that Semi-MedRef consistently outperforms both fully supervised and semi-supervised baselines across all label regimes.

Deep neural networks are vulnerable to adversarial perturbations, limiting deployment in safety-critical applications such as synthetic aperture radar (SAR) automatic target recognition (ATR). Randomized smoothing improves robustness by averaging predictions over noisy inputs, but isotropic noise often fails to preserve the semantic structure of SAR imagery. We propose semantic smoothing, a defense that replaces noised-based perturbations with structured randomized transformations generated by a novel view synthesis model. For SAR, we condition on acquisition geometry to synthesize multiple plausible radar views. Predictions across generated randomized views are aggregated to form a robust classifier. Experiments show that semantic smoothing improves robustness against standard attacks, such as FGSM and PGD, and SAR-specific attacks, such as OTSA and SMGAA, while also increasing clean classification accuracy. These results demonstrate that randomized smoothing via semantically preserving geometric transformations is a promising alternative to isotropic noise for adversarial defense in structured sensing domains.

Accurate medical image segmentation is fundamental to precision medicine, yet robust delineation remains challenging under heterogeneous appearances, ambiguous boundaries, and large anatomical variability. Similar intensity and texture patterns between targets and surrounding tissues often lead to blurred activations and unreliable separation. We attribute these failures to representation collapse during encoding and insufficient fine grained multi scale decoding. To address these issues, we propose Med DisSeg, a dispersion driven medical image segmentation framework that jointly improves representation learning and anatomical delineation. Med DisSeg combines a lightweight Dispersive Loss with adaptive attention for fine grained structure segmentation. The Dispersive Loss enlarges inter sample margins by treating in batch hidden representations as negative pairs, producing well dispersed and boundary aware embeddings with negligible overhead. Based on these enhanced representations, the encoder strengthens structure sensitive responses, while the decoder performs adaptive multi scale calibration to preserve complementary local texture and global shape information. Extensive experiments on five datasets spanning three imaging modalities demonstrate consistent state of the art performance. Moreover, Med DisSeg achieves competitive results on multi organ CT segmentation, supporting its robustness and cross task applicability.

Medical image segmentation remains challenging in low-data regimes, where scarce annotations often yield poor generalization and ambiguous boundaries with missing fine structures. Recent self-supervised pretraining has improved transferability, but it often exhibits a texture bias. In contrast, accurate segmentation is inherently geometry-aware and depends on both topological consistency and precise boundary preservation. To address this problem, we propose a two-stage framework that couples structure-aware encoder pretraining with boundary-oriented decoding. In Stage-1, we aim to learn structure-aware representations for downstream segmentation in low-data regimes. To this end, we propose Mixed-Domain MeanFlow Pretraining, which aligns images and binary masks in a shared latent space through latent transport regression, where masks act as conditional structural guidance rather than prediction targets, making the pretraining task-agnostic. To further improve training stability under scarce supervision, we incorporate a lightweight Dispersive Loss to prevent representation collapse. In Stage-2, we fine-tune the pretrained encoder with a lightweight decoder that combines Direct Attentional Fusion for adaptive cross-scale gating and Frequency-Directional Dynamic Convolution for high-frequency boundary refinement under appearance variation. Experiments on ISIC-2016, Kvasir-SEG, and GlaS demonstrate consistent gains over state-of-the-art methods, with improved robustness in low-data settings and sharper boundary delineation.

Single-unit crown restoration is among the most common procedures in clinical dentistry, with CAD/CAM workflows now designing crowns directly from intraoral scans. Partial scans are often preferred over full-arch scans for single-unit cases due to fewer stitching errors, yet most segmentation networks trained on full arches fail on partial scans, while end-to-end generative crown methods often produce over-smoothed surfaces that lose occlusal detail. We propose an end-to-end pipeline that takes a raw intraoral scan and target FDI tooth number as input and outputs an initial, patient-specific crown proposal for clinician refinement. The pipeline has three phases: (I) data preparation and pose standardization; (II) segmentation routed by scan type; and (III) crown proposal generation via context-aware retrieval and Blender-based fitting. We address partial-scan segmentation through a classify-then-align strategy: a DGCNN classifier categorizes the scan into one of five anatomical types, then coarse-to-fine RANSAC+ICP registration standardizes the jaw coordinate frame, followed by graph-cut optimization to refine tooth-gingival boundaries. Trained on 1,958 partial scans, the pipeline achieves macro-average DSC 0.9249, Recall 0.8919, and Precision 0.9615 across 17 semantic classes; a fine-tuned full-arch model reaches DSC 0.9347. The prepared tooth and its mesial and distal neighbors achieve DSC 0.9468-0.9569 with sub-millimeter Centroid Errors (0.2666-0.2774 mm). These centroids anchor a retrieval module using DGCNN embeddings and cosine similarity over neighboring and opposing teeth, followed by spline-guided alignment and Blender Python API refinement. The pipeline produces a preliminary crown shell in 2.5-3.5 minutes, offering a practical alternative to end-to-end generative approaches.

Automated analysis of peripheral blood smears for Acute Lymphoblastic Leukemia (ALL) is hindered by low contrast and substantial variability in cytoplasmic appearance, which complicate conventional membrane-based segmentation. We found that many recent approaches rely on heavy neural architectures and extensive training, but still struggle to generalize across staining and acquisition variability. To address these limitations, we propose the Perinuclear Ring-based Image Segmentation Method (PRISM), which replaces explicit cytoplasmic delineation with adaptive concentric zones constructed around the nucleus. These perinuclear regions enable the extraction of robust cytoplasmic descriptors by integrating color information with texture statistics derived from grey-level co-occurrence patterns, without requiring accurate cell-boundary detection. A calibrated stacking ensemble of traditional classifiers leverages these descriptors to achieve a high performance, with an accuracy of 98.46% and a precision-recall AUC of 0.9937.