Volume

Annotating large radiology datasets is bottlenecked by the manual effort of delineating structures slice-by-slice in 3D volumes. Interactive methods reduce this effort but stay interaction-inefficient: slice-wise methods (including many foundation models) ignore inter-slice continuity, while 3D and video-based methods propagate a prompt with a \emph{fixed} propagator that never adapts to the target volume, so it drifts on low-contrast or pathological structures and must be re-prompted. We present IMVS, a human-in-the-loop annotation framework that composes three components into a closed loop rather than a new segmentation primitive: a lightweight 2D Slice Mask Adapter (SMA) fine-tuned online from user scribbles, a frozen Volume Mask Tracker (VMT) that propagates corrected masks across adjacent slices, and a soft teacher--student alignment that limits forgetting. The SMA is backbone-agnostic (UNet++, DeepLabV3, TransUNet). Across 8 public CT/MRI datasets, IMVS matches strong interactive baselines in quality while sharply cutting annotation effort: $14.4\times$ faster than a proficient copy-based manual workflow ($22.3\times$ over naive manual), $4.6\times$ over slice-wise and $1.9\times$ over 3D interactive methods. MedSAM2 and ScribblePrompt stay competitive or stronger on well-delineated organs; IMVS's advantage is largest on challenging targets and on interaction efficiency. Source code and Demo Video: https://github.com/AbhilakshSinghReen/imvs.

The larval stage of Drosophila melanogaster is a compact model system for neuroscience whose genetic toolkit allows fluorescent markers to be expressed in defined neural populations, and comparing the resulting expression patterns across animals requires every brain to be registered into a shared anatomical reference space. Existing pipelines for this task are predominantly based on classical registration methods, which perform a new optimization for each volume, often require per-case parameter tuning, and can take minutes per brain, limiting their use as a routine preprocessing step. We present a trained deep registration pipeline that deformably aligns a larval brain to a reference template in a single forward pass at high spatial resolution, on volumes that hold several times more voxels than those learned 3D registration is normally reported on, together with the preprocessing and anatomy-anchored evaluation pipeline required to apply it. Against eleven classical and seven further learned baselines on a held-out collection acquired with different acquisition and quality strata, the proposed pipeline is the most accurate, improving on the strongest classical baseline by 23 percentage points of anatomical landmark-local mutual information. It registers a volume one to two orders of magnitude faster than the classical deformable pipelines, and it retains more of its accuracy than any other method as acquisition quality degrades. The network, its trained weights and the full pipeline are released as the open-source deep larval brain registration framework: https://github.com/agentdr1/deep-larval-brain-reg

Uncertainty arising from inter-observer variability in medical image segmentation plays an important role in developing treatment plans. Research in this area is inhibited by the lack of multiple annotations for large-scale medical datasets, especially for volumetric data, which suffers from additional scaling and computational complexity challenges. Flow matching has emerged as a powerful framework for generative modelling and has also been demonstrated to maintain strong performance when working with latent representations of images. In this work, we introduce a latent-to-latent flow technique for stochastic segmentation of medical volumes via encoded representations of both the image and label space. We evaluate our method on two challenging applications covering delineation uncertainty for radiotherapy planning and multiple organ structure segmentation, improving efficiency up to 14x compared with full resolution models while maintaining clinically relevant performance.

Digital volume correlation (DVC) provides three-dimensional full-field displacement measurements from volumetric images, but how the internal resolution of a machine-learning-based DVC model affects accuracy and operating range remains poorly understood. Here, we present RAFT-DVC, a resolution-aware family of recurrent all-pairs field transforms (RAFT)-based DVC solvers with encoder downsampling factors s = 2, 4, and 8. Using a matched design, we find that the three solvers localize displacement to approximately 0.017 feature-grid voxel, giving an empirical raw-volume error scaling of approximately 0.017s voxel. The solvers exhibit complementary operating regimes governed jointly by displacement reach and volumetric-texture compatibility. Synthetic benchmarks show that RAFT-DVC achieves errors of the same order as tuned classical DVC under fine-texture, small-to-moderate-displacement conditions and becomes competitive or advantageous under coarse-texture, large-displacement conditions. Frequency-swept tests quantify deformation spatial resolution, while tiled inference enables dense estimation on large volumes. Evaluation on confocal volumetric images acquired during indentation illustrates the importance of matching solver operating regime to deformation magnitude and image texture. Tests on micro-CT images of elastomeric foam, despite training only on particle-labeled synthetic data, provide evidence of cross-texture transfer. We also identify coordinate-order inconsistencies in three-dimensional RAFT correlation sampling and introduce a non-cubic impulse test to verify sampler geometry independently of network training. Correcting the sampler improves native-input accuracy and generalization to unseen volume dimensions. Together, these results establish RAFT-DVC as a fast, resolution-aware framework for dense DVC with characterized accuracy and operating regimes.

Faithfully capturing diverse real-world objects with fuzzy, anisotropic structures, such as hair, fur, fibers, and textiles, for efficient real-time visualization remains challenging. Recent radiance field reconstruction methods capture these structures from multi-view images using translucent volumetric primitives such as 3D Gaussians rather than opaque low-dimensional primitives (e.g., triangles, line segments, and polylines), thereby limiting compatibility with standard depth-tested rasterization, reflection modeling, and physical simulation. We present an inverse rendering method for reconstructing fuzzy geometry using explicit line segments, which are rasterized on a subpixel grid for anti-aliasing to reproduce a semi-transparent appearance. While straightforward to render, optimizing numerous line primitives to match target images poses a significant challenge. We address this by introducing a stochastic differentiable rasterizer for line segments that produces informative gradients with respect to vertex positions, attributes, and discrete connectivity. Experiments on synthetic and real-world datasets show that our method outperforms surface-based approaches in capturing fuzzy boundaries and achieves quality comparable to volumetric representations while relying entirely on explicit geometry. The resulting representation integrates seamlessly with standard graphics pipelines, enabling cross-platform rendering, various shading models, and physical simulation.

Volumetric video enables immersive free viewpoint rendering of dynamic real world scenes, yet existing methods struggle with long sequences and complex motions, often leading to temporal instability and visual artifacts. To address these challenges, we propose \ourname, a Gaussian splatting based framework for volumetric video reconstruction. Our key insight is that explicitly tracking long term complex motion with individual Gaussian primitives is inherently unstable. Instead, we organize Gaussians around time conditioned anchors that localize their spatial and temporal support, thereby reducing long range motion complexity. We further introduce a temporal windowing strategy to activate only anchors relevant to the queried time, which improves scalability and temporal coherence. In addition, to ensure spatial and temporal stability, we design a compact set of multi level anchor features that encode global features, local spatial features, and local temporal features, jointly constraining Gaussian generation. Extensive experiments demonstrate that \ourname \ consistently outperforms prior methods on long sequence volumetric videos with complex motions. Project page: https://github.com/WuJH2001/ATGS.

Volumetric video streaming turns privacy into a 3D, multi-view problem. Unlike ordinary video, where sensitive content can often be redacted frame by frame, RGB-D volumetric pipelines capture people, rooms, and personal objects from multiple cameras and fuse them into a shared 3D representation. A private object missed in one view, or only partially removed before fusion, can therefore reappear in the reconstructed scene. This creates a privacy challenge for 3D telepresence, education, entertainment, and immersive applications: private content should be removed before raw visual and geometric data leave the camera side, while the public part of the scene should remain useful for real-time reconstruction. Existing volumetric streaming systems mainly optimize reconstruction, data movement, and latency, while privacy-preserving vision methods are designed for single-camera, single-frame images and do not directly address calibrated multi-view RGB-D fusion. We present InViStream, a real-time "privacy-from-source" system designed for this setting. InViStream addresses three challenges in volumetric capture: private objects may appear differently across views, RGB masking alone can leave geometric privacy leakage in depth, and public/private instances of the same class must be separated consistently before cloud-side fusion. To address these challenges, InViStream combines object detection with depth-aware masking, propagates public/private decisions across calibrated views, and fuses only sanitized point clouds. We evaluate InViStream on synthetic and real RGB-D scenes, including offices, conference rooms, living rooms, and settings with multiple public and private people and objects. InViStream achieves synthetic Dice/Recall of 0.799/0.891 and real Dice/Recall of 0.792/0.908, with synthetic SSIM above 0.98 and real-time streaming above 30 FPS.

Explainability is essential for deploying deep learning models in high-stakes medical applications. Existing explainability methods for volumetric imaging predominantly operate in voxel space, overlooking the structured representations introduced by recent advances in 3D scene modeling. We present COGENT (Counterfactual Gaussian Explanations), a framework that generates counterfactual explanations directly in the parameter space of Gaussian-based volumetric representations. Built upon MedGS and the Sybil lung cancer risk prediction model, COGENT optimizes selected Gaussian primitives through a differentiable rendering pipeline, enabling gradients from the downstream predictor to identify representation components that most influence model decisions. Unlike conventional pixel- or voxel-level attribution methods, our approach formulates explainability as a counterfactual optimization problem over an explicit 3D scene representation, producing sparse and spatially localized explanations while preserving anatomical consistency. We evaluate COGENT on lung CT scans using quantitative comparisons with existing explainability methods together with qualitative analysis by medical experts. The results demonstrate that representation-space counterfactual optimization provides clinically meaningful explanations while offering a new perspective on interpreting volumetric deep learning models.

Cross-modality medical image translation can reduce the burden of multi-modal acquisitions, yet the field remains constrained by two coupled limitations: methods operate on 2D slices or 3D patches rather than whole volumes, and train a separate model for each translation task. Both stem from a single cause, the absence of a sufficiently strong volumetric prior, which forces generative models to learn anatomical appearance and cross-modality mapping simultaneously, an ill-posed problem at the scale of available paired datasets. We propose to decouple these objectives. A large-scale pretrained 3D variational autoencoder provides a compact latent representation of volumetric appearance, reducing translation to a conditional flow-matching problem. This compression makes whole-volume processing tractable, while a resolution-aware sampling strategy preserves native anatomical scale. We train a single model jointly across inter-modality (MRI$\to$CT, CBCT$\to$CT) and intra-modality (MRI$\to$MRI) tasks over three multi-center datasets. Across all tasks, whole-volume processing outperforms its patch-based counterpart, and the multi-task model matches task-specific baselines while replacing $N$ networks with one. Crucially, joint training unlocks capabilities inaccessible to task-specific approaches: zero-shot generalization to anatomical regions unseen during training, within 0.15 SSIM of the fully supervised model, and compositional cross-dataset translation along paths never directly supervised. These results suggest that combining a strong volumetric prior with multitask training is a scalable route toward synthesis systems that generalize beyond their training distribution. Code is available at https://github.com/arco-group/Whole-Volume-Latent-FM.

Gaussian-splatting proxies enable interactive rendering of volumetric medical scans, but a clipping plane exposes anatomy not constrained by external-view training and intersects primitives that conventional splatting can only keep or drop whole. We present XClipGS (eXact Clipping), which treats these as two separate problems: the render-time clip operator and supervision of the hidden interior. Under the local affine model used by EWA splatting, the ray integral of a half-space-restricted Gaussian factorizes exactly into its ordinary 2D footprint and a conditional Gaussian CDF whose argument is affine in pixel coordinates. The resulting closed-form per-pixel operator introduces no learned clipping parameters or auxiliary network and remains differentiable with respect to the primitive and plane. We use multi-distance reference views with varied clipping-plane axes and offsets to supervise the interior through the same operator. We also introduce a paired clipped/unclipped cut-face protocol with difference-referenced cut error (CDE) and culled-side leakage (Leak), because global image metrics dilute errors near the plane. On eight CT and MRI volumes with plane offsets not used for training, XClipGS attains the highest PSNR on every volume (33.56 versus 32.34 dB for ClipGS) while rendering at over 650 FPS, far above real time, versus 278 FPS. On voxel-axis cut-face views, it raises average band SSIM from 0.809 to 0.860 and leaks roughly 40 times less. Without retraining, it also achieves the best average across all four metrics on arbitrary-normal planes; on a fixed interior, it matches RaRa's face fidelity with about 16 times less leakage. Project page: https://gaozhongpai.github.io/XClipGS/

Estimating volumetric mechanical properties, including Young's modulus, Poisson's ratio, and density at each voxel, is intrinsically ambiguous from vision alone, as visually similar objects may have substantially different material compositions and physical behavior. Existing approaches predict these properties independently across voxels, overlooking the piecewise-constant material structure of real objects and producing noisy or inconsistent estimates for voxels that share the same material, while lacking an explicit mechanism to resolve visual ambiguity. We introduce ViWi (Vision Meets WiFi), an object-centric framework for volumetric mechanical-property estimation. ViWi represents each object using a compact set of material slots that aggregate evidence from voxels with a shared material identity and produce coherent slot-level property predictions. To complement visual appearance, ViWi incorporates a compact RF descriptor generated through WiFi-band electromagnetic simulation using permittivity and conductivity. The RF descriptor conditions the material slots with global composition cues that may be unavailable from images, while visual features preserve voxel-level spatial localization. Across volumetric mechanical-property and mass-estimation benchmarks, ViWi improves over the prior state of the art on four of six per-voxel metrics, while its vision-only variant improves all mass-estimation metrics. These results demonstrate that combining object-centric material structure with complementary RF evidence enables more accurate and physically coherent volumetric property estimation beyond what is possible from visual appearance alone.

Slice-wise 2D object detectors are increasingly applied to volumetric data due to their computational efficiency and scalability, yet they often yield fragmented and unstable predictions along the depth axis. We propose YOLO-PVC, a lightweight and model-agnostic framework for 2D-to-3D consolidation of slice-wise detections. The method enforces depth continuity, aggregates bounding box coordinates using robust percentile statistics, and further refines axial extent through a lightweight MLP-based calibration module. Unlike naïve stacking or averaging strategies, YOLO-PVC explicitly addresses missing detections and outlier slices along the depth dimension. Experiments on 3D liver MRI volumes across three tumor categories demonstrate consistent improvements over multiple aggregation baselines. The heuristic PVC achieves an overall $\mathrm{IoU}_{3D}$ of $0.665$, while the calibrated variant further improves performance to $0.710$, with high planar overlap ($\mathrm{BEV\ IoU} \approx 0.78$). These results demonstrate that structured geometric consolidation provides an effective and practical solution for volumetric liver tumor localization in clinical MRI.

Multimodal medical large language models remain structurally weak for neuro-oncology because volumetric evidence is compressed into generic visual tokens and diagnostic conclusions often lack an auditable link to MRI regions. We present NeuroMosaic, a 3D multimodal language model that converts multi-sequence brain MRI into anatomy-indexed regional tokens, aligns them with clinical narrative and molecular concepts, and generates evidence-linked outputs. The architecture combines a multi-resolution volumetric tokenizer, a neuroanatomical graph router, a molecular concept memory, and selective risk control. Across four glioma cohorts, NeuroMosaic achieved an internal subtype macro-F1 of 0.827 and external macro-F1 values of 0.784, 0.761, and 0.742. On UPenn-GBM, it improved over the strongest matched-input baseline by 3.6 percentage points (95% CI: 1.8 to 5.4, adjusted p = 0.0018), with IDH, 1p/19q, and MGMT AUROCs of 0.918, 0.861, and 0.781. Evidence pointing accuracy reached 0.703, and targeted evidence deletion reduced correct-answer probability by 0.187, compared with 0.046 for random deletion. These results establish anatomy-indexed routing as a measurable mechanism for accurate, grounded, and calibrated volumetric medical-language reasoning.

Scaling the corpus is the default remedy when a contrastive representation lacks an attribute. We report a case where it does nothing, and identify what does: adding a lexical-speech round to a frozen-base multimodal embedding model raises zero-shot keyword spotting by 76 points while reducing speech-emotion recognition by 14. The loss is not a capacity limit: fine-tuning on 7,442 clips from a prosody-controlled corpus recovers emotion past its pre-speech level at a five-point keyword cost. Nor is it data volume: 29,428 mined clips whose captions explicitly name emotions, at matched exposure, move emotion by -0.0007. The difference is structural: a contrastive objective encodes an attribute only when the in-batch negatives cannot be separated without it; the controlled corpus holds sentence content fixed, so prosody is the only separating signal, whereas mined captions name emotion yet remain separable by scene content. Intervention on the same audio confirms causality: raising caption similarity does not recover emotion, but collapsing caption diversity so that emotion becomes the only separating axis recovers it by 8.9 points across three seeds, with a smaller, same-signed gain on a non-acted corpus, while keyword accuracy trades back. Corpus structure, not size or caption vocabulary, controls what a contrastive audio embedding encodes.

Time-varying implicit neural representations (INRs) provide a compact representation of scientific volumes and, for modalities such as dynamic X-ray computed tomography (CT), are often the only practical way to represent the data. However, interactive volume rendering of INRs is challenging, as cheap memory lookups are replaced by expensive neural inferences, hindering the performance. Therefore, conventional volume rendering methods such as ray marching with dense sampling are often impractical. While resampling, caching, and retraining can mitigate this cost, they compromise convenience and accuracy and become impractical for time-varying data. We tackle these challenges using a query-efficient stochastic volume rendering framework based on delta tracking. Our system employs a four-stage pipeline that exploits heterogeneous parallelism, using ray tracing cores for traversal and tensor cores for batched neural evaluation. Furthermore, we present strategies to reduce INR queries via ray budgeting and query pruning, thereby increasing per-frame performance. Using our renderer, many time-varying INRs can be rendered directly from their original representation. The system achieves ~30-40 FPS at 1024x1024 resolution on an RTX 4090 GPU and converges to high-fidelity images. Moreover, the system enables interactive temporal exploration of the continuous domain, with timestep updates taking approximately 1-2 ms.

Integrating 3D medical images with vision-language models (VLMs) holds substantial promise for computer-aided diagnosis. However, volumetric images generate prohibitively long visual-token sequences with considerable spatial and inter-slice redundancy. Existing token compression methods typically apply uniform reduction or rely on a single importance signal, increasing the risk of removing regions that are clinically relevant to the query or structurally distinctive. To address this limitation, we propose MedARC, a unified, training-free framework for Adaptive Redundancy Compression of visual tokens in 3D medical VLMs. MedARC estimates token importance by integrating three complementary cues: self-attention from the VLM vision encoder, which reflects the model's intrinsic visual focus; similarity between projected visual tokens and text embeddings, which identifies query-relevant regions; and deviations of local visual foundation model features from the volume-level feature center, which highlight structurally distinctive anatomy. The resulting importance distribution guides a saliency-aware merging strategy that preserves informative tokens while consolidating redundant ones rather than simply discarding them. Experiments on CT-RATE and MR-RATE show that MedARC reduces visual-token overhead and inference time while preserving or improving diagnostic performance. Its multi-cue scoring cost is outweighed by the savings from processing fewer tokens, with greater benefits expected for larger language models.

We introduce a method for training a text-conditioned segmentation model for CT scans, which combines voxel-level supervision with coarse but scalable slice-level supervision from reports. We extract, from a large database of scan-report pairs, descriptions of findings with indices of slices where those findings occur. We then finetune a general-purpose 2D image segmentation model, SAM3, with standard segmentation losses from strongly labeled data and with a slice-level classification loss from the extracted weak supervision. Our results on the ReXGroundingCT dataset illustrate that this strategy improves the segmentation dice score: from an 8% relative gain when there are 1000 fully labeled volumes to 22% when there are 250 fully labeled volumes.

Objective: Concept bottleneck models route prediction through interpretable intermediate variables, and their validity is normally judged by how accurately those variables are predicted. We ask whether that judgement is sufficient, using left ventricular volumes as the concepts underlying ejection fraction estimation from echocardiographic video. Methods: A video transformer encoder was trained on a publicly available echocardiography dataset. End-systolic and end-diastolic volumes formed a concept layer from which ejection fraction was computed analytically, with no residual path to the output. We compared training under an ejection fraction objective alone against training with additional supervision of the volumes in millilitres, and evaluated both on 1276 held-out studies. Results: The concept bottleneck did not increase ejection fraction error relative to direct regression, at 6.89 against 7.13 mean absolute error. Without volume supervision, however, the spread of predicted volumes collapsed to 0.1 millilitres against reference spreads of 35.7 and 45.7 millilitres, while correlation was partly preserved. We show that this follows from an invariance property of the objective: ejection fraction is a ratio and is unchanged when both volumes are rescaled, so the loss determines the concept layer only up to scale. Supervision in absolute units reduced volume error from 89.8 to 25.8 millilitres at a cost of 0.4 in ejection fraction error. Conclusion: Concept accuracy alone can conceal a concept layer that carries no physical scale. Significance: Interpretable intermediate variables in clinical models should be validated against the invariance structure of the training objective, not only against prediction accuracy.

Medical image visualization requires volumetric rendering algorithms that preserve anatomical fidelity while maintaining high rendering speeds. To address the high computational cost of large volumetric datasets, we propose a Gaussian-based volumetric representation for efficient visualization of dense medical volumes without compromising structural and radiometric details. We optimize the proposed representation using Monte Carlo volumetric estimation, which enables training on a highly sparse subset of voxels while maintaining consistency with the dense volumetric objective. In addition, we introduce a curriculum learning strategy that progressively incorporates structured slice-based sampling during training. Sparse voxel samples provide an early global coverage of the volume, while slice samples capture spatially correlated regions that aid geometric structure and texture continuity. This combination enables the Gaussian representation to learn anatomical details of various structures and corresponding textures from sparse supervision while significantly reducing the computational cost associated with dense voxel processing. The learned representation supports slice-based rendering methods such as shear-warp volume rendering, enabling efficient visualization of multimodal medical datasets including MRI and Cryosection volumes while preserving anatomical structures. Using sparse supervision, our method achieves up to 43.86 FPS rendering with a compression ratio of 11.31:1.

Implicit neural representations (INRs) for time-varying volumetric data are typically trained using dense sampling over spatiotemporal coordinates, where each observation corresponds to a single point in space and time. This coordinate-wise formulation requires extensive sampling during optimization, leading to high computational cost and inefficient use of temporal structure. In this work, we revisit this design choice and show that dense spatiotemporal sampling is not necessary for learning time-varying fields. Instead, we represent the data as a collection of spatially indexed time series and train INRs using sequence-level supervision over each spatial location, rather than coordinate-wise scalar samples. This reformulation eliminates the need for dense spatiotemporal sampling and instead learns each spatial location from its full temporal evolution in a structured manner. We demonstrate that this representation is compatible with a range of existing INR architectures and consistently improves reconstruction quality, while significantly reducing training cost. Furthermore, we show that this formulation can be combined with mixture-of-experts architectures, and that our MoE instantiation further improves reconstruction quality compared to both the base reformulation and existing MoE-based INR methods, providing a stronger capacity allocation under heterogeneous temporal dynamics.

Recent advances in differentiable Gaussian splatting have highlighted the potential of primitive-based approaches as alternative scene representations for interactive, high-quality, volume visualization (VolVis) of large datasets. However, the explicit nature of current primitive-based methods, combined with isolated optimization for each VolVis scene, results in redundant, non-compact representations. We present ECoNGS, an efficient compressive neural Gaussian splatting framework for VolVis scene representation. ECoNGS employs lightweight neural networks to dynamically predict implicit, editable Gaussian splats from explicit anchor points, effectively combining model compactness and parameter efficiency of implicit representations with high-performance rendering of explicit primitives. We explore a joint learning strategy that clusters geometrically similar scenes and shares parameters across them, significantly reducing overall training time and model size while maintaining reconstruction fidelity. To achieve a more compact scene representation, we further compress the explicit anchor attributes using a neural entropy model that estimates their probability distributions, enabling compact storage via entropy coding. We systematically investigate Gaussian initialization strategies and propose a simple yet effective scheme tailored for VolVis scenes, improving reconstruction accuracy and accelerating convergence. We evaluate ECoNGS qualitatively and quantitatively across various univariate and multivariate VolVis scenes, highlighting its superior performance over prior methods in training time, reconstruction quality, and model size. In particular, compared with the prior method iVR-GS, ECoNGS improves reconstruction quality by up to 2.2 dB in PSNR while reducing the model size by up to 6.1x and the training time by up to 5.9x. The code is available at https://github.com/TouKaienn/ECoNGS.

Large-scale scientific simulations generate volumetric data at rates that far outpace advances in storage and network bandwidth, making effective lossy compression increasingly critical. However, conventional compressors often struggle to preserve fine structural details at high compression ratios (CRs), and implicit neural representations (INRs) require costly per-volume optimization and produce models with fixed CRs. To respond, we present EVOLVE, an autoencoder (AE)-based volume-compression framework that targets high CRs for offline compression, with three key contributions. First, we construct a large-scale cross-domain database of 6,376 volumes from 21 scientific simulations, curated via perceptual hashing to ensure diversity, enabling the optimized model to extract features that generalize across volumes within the covered scientific simulation domains. Second, we reexamine the design space of AE-based compressors and incorporate several macro- and micro-designs into a vanilla AE to develop EVOLVE, which substantially improves the expressive power and compression capability. Third, we develop a learnable gain mechanism with a three-stage training strategy to enable variable-rate encoding, allowing a single model to support continuous CR adjustment at inference time. Experiments on multiple unseen scientific simulation datasets demonstrate that EVOLVE achieves substantially higher CRs than conventional compressors at comparable reconstruction quality, while delivering compression speeds that are orders of magnitude faster than INR-based methods, highlighting its promise as a strong alternative for compressing scientific data. The code, model weights, and results are available on our project page at https://evolve-vis.github.io.

Implicit neural representation (INR) methods provide continuous coordinate-to-value mappings and integrate naturally with direct volume rendering, making them attractive for representing volumetric data. However, existing INR-based approaches for volumetric data are inherently lossy, and even small reconstruction errors can propagate through rendering and downstream analysis. In this work, we explore Lossless-INR, a lossless INR framework for 3D scientific volumetric data based on bit-plane decomposition. By decomposing each voxel value into binary bit-planes, we reformulate reconstruction as per-bit binary classification, so that exact recovery reduces to predicting every bit correctly. To make this optimization tractable while keeping the representation compact, we combine an octree block-partitioning strategy that adaptively subdivides complex regions with a ternary feature-grid network whose grid entries are parameterized by a ternary set of values. Experiments on diverse volumetric datasets show that this design can achieve zero bit-error rate and bit-exact reconstruction, enabling faithful rendering and downstream analysis with a compact representation. The code is available at https://github.com/TouKaienn/Lossless-INR.

Computed Tomography (CT) carries significant ionizing radiation risks, driving the need for sparse-view reconstruction. Implicit scene representations (ISRs) address this by recovering continuous volumetric attenuation fields directly from sparse projections, and recent geometry-aware extensions jointly model surface geometry alongside attenuation to improve fidelity and enable clean tissue segmentation without manual thresholding. However, these methods remain limited by manually tuned attenuation bounds and rigid two-material constraints. This paper proposes $K$-NeAS, a unified and scalable architecture for automated, multi-material surface reconstruction. We replace independent material networks with a shared latent backbone and introduce a fully differentiable $K$-material sequential soft selector to model an arbitrary number of overlapping tissues. To eliminate manual tuning, we automate attenuation bounding using a Gaussian Mixture Model (GMM) and implement a scheduled auxiliary floater loss to mitigate geometric hallucinations common under extreme sparsity. Evaluated across four clinical Cone-Beam CT (CBCT) datasets, $K$-NeAS successfully scales to arbitrary material counts, achieving superior 3D volumetric fidelity at $K=3$ materials on complex multi-tissue regions such as the Abdomen ($33.28\text{ dB}$ 3D PSNR vs. $31.40\text{ dB}$ single-material NeAS baseline, a $+1.88\text{ dB}$ improvement). Furthermore, our model exhibits enhanced robustness under sparse-sampling conditions, outperforming baseline 3D PSNR by up to $1.17\text{ dB}$ under 5- and 10-view constraints.

While Multimodal Large Language Models (MLLMs) have demonstrated remarkable success in 2D medical image understanding, their extension to 3D volumetric imaging remains hindered by prohibitive annotation costs and dataset opacity. Current data formats, predominantly consisting of rigid Visual Question Answering (VQA) pairs or unstructured final clinical reports, typically fail to capture explicit clinical reasoning. To address this limitation, we introduce a large-scale structured reasoning dataset constructed via a novel slice-wise data synthesis paradigm. Inspired by the genuine diagnostic workflow of radiologists, this paradigm models visual cognition by decomposing the complex 3D reading process, translating global clinical priors into fine-grained, per-slice observations that are subsequently synthesized into an interpretable Chain-of-Thought (CoT). Crucially, this synthesized reasoning framework enforces essential clinical principles: sequential spatial tracking, multi-slice spatial awareness for artifact mitigation, and differential exclusion. To validate this approach, we instruction-tune a standard 2D-pretrained MLLM baseline using the synthesized data to enhance its volumetric comprehension. Comprehensive evaluations across multiple 3D medical benchmarks demonstrate that our method yields significant performance improvements over the 2D baseline. Furthermore, the resulting model exhibits robust spatial reasoning capabilities and rivals resource-intensive native 3D architectures, effectively bridging the performance gap. Ultimately, this data-centric strategy unlocks deep volumetric understanding and highly interpretable clinical logic without requiring computationally expensive 3D-specific pre-training. The complete repository, including datasets and training workflows, is publicly available at https://github.com/2020420145009/hounsfield.

Accurate 3D scene understanding is fundamental to embodied intelligence and autonomous driving, where 3D occupancy provides a unified representation of objects, structures, and free space. However, recovering such a complete volumetric representation from visual observations remains challenging, particularly in occluded and unobserved regions. Visual geometry priors offer strong and generalizable geometric cues for addressing this challenge, but their outputs are inherently surface-centric, whereas occupancy prediction requires reasoning about volumetric interiors and free space. To bridge this gap, we introduce GPOcc, which transforms visual geometry priors into occupancy-aware sparse Gaussian representations for efficient and expressive volumetric scene modeling. Building on GPOcc, GPOcc++ models multi-view observations and temporal sequences within a unified framework, allowing spatial and temporal evidence to be handled through the same representation. We further extend GPOcc++ from indoor scenes to outdoor occupancy prediction. Extensive experiments on both indoor and outdoor benchmarks demonstrate consistently strong performance across both multi-view and temporal settings, together with favorable efficiency and generalization. Code will be released at https://github.com/JuIvyy/GPOcc.

Prefabricated prefinished volumetric construction moves most building work into module factories, whose production floor operates as a flexible job shop. A major complication is decisive: long post-operation time-lags caused by concrete curing, watertightness ponding tests, and paint drying, during which a module is blocked while its workstation stays free. On benchmark instances grounded in an official national prefabrication guidebook, these lags inflate even the optimal reference makespan by about 67% on average, and ignoring them at decision time, then repairing to feasibility, is worse than every dispatching rule. We adapt a state-of-the-art dual-attention deep reinforcement learning solver through three minimally invasive, individually ablatable extensions: lag-aware dynamics with an admissible reward bound, two anticipatory lag feature channels, and liveness-masked operation- and station-type embeddings. With every extension disabled the implementation reproduces the original solver exactly, so all gains are attributable to the adaptations. We release a public, guidebook-grounded benchmark generator. On held-out instances the learned policy is the strongest solver-free scheduler: it reaches within about 4% of a constraint-programming reference and beats every dispatching rule and a genetic-algorithm metaheuristic, with its advantage widening under capacity contention, and a single size-mixed policy carries this lead across the trained range of factory sizes. It needs no solver, model, or license in the loop and re-plans within seconds of a disruption; where an exact solver can be deployed, that solver remains the quality ceiling, a boundary we map explicitly.

In this paper, we propose a training strategy for confidence estimation in omnidirectional stereo, targeting the ambiguous matches that frequently occur in wide-baseline setups. Reinterpreting the matching responses produced by the 3D encoder decoder block, we show that their expectation values provide intrinsic confidence signals. Building on this, our method directly penalizes ambiguous responses without auxiliary heads, multi-pass inference, or additional modules, resulting in more efficient and generalized predictions. Beyond confidence, we introduce swept feature volume resampling, where response features produced by 3D CNNs are resampled using regressed positive matching indices and then processed by 2D CNNs to predict meta-information such as surface normals. This joint learning introduces auxiliary geometric regularization and improves depth coherence by leveraging additional contextual cues during response aggregation stage. Experimental results demonstrate that our approach enhances both confidence estimation and surface normal prediction while maintaining deployment practicality for autonomous mobility applications.

Reconstructing the pulmonary vascular tree from computed tomography (CT) images is essential for quantitative lung analysis, vascular morphology assessment, and patient-specific modeling, yet it remains challenging because vessels span multiple scales, from proximal arteries to distal microvasculature. Clinical chest CT is further affected by limited spatial resolution, partial volume effects, heterogeneous image quality, and respiratory motion artifacts. Unlike deep learning-based pulmonary vessel segmentation methods that require large annotated datasets, we propose a deterministic, training-free, and explainable pipeline for CT-based pulmonary vascular tree reconstruction. The method fuses multiscale Hessian-based Frangi and Sato vesselness filters using a weighted maximum response across 12 spatial scales from 1 to 8 mm, enabling detection of large pulmonary arteries and peripheral branches. Lung parenchyma is segmented by Hounsfield unit thresholding, morphological post-processing, and Chan-Vese active contour refinement. Vascular centerlines are extracted using the Kimimaro implementation of the TEASAR algorithm; separate left- and right-lung vascular graphs are then constructed, pruned, and verified for acyclicity. Geometric plausibility is assessed using volumetric fractal dimension, Strahler order analysis, Horton ratios, and Murray's law. The resulting fractal dimension of approximately 2.3 is consistent with reported values for the human pulmonary vasculature. At the same time, residual deviations in branching metrics reflect distal-vessel truncation caused by finite CT resolution. These results indicate that the proposed explainable pipeline can generate geometrically plausible pulmonary vascular tree models and may support quantitative pulmonary imaging, vascular morphometry, and computational lung modeling.

Accurate patient-specific tetrahedral cardiac meshes are essential for in-silico trials, yet common segmentation-then-modelling pipelines can blur thin-wall anatomy and offer limited cross-case correspondence. We propose HeartVolMesh, which lifts each template vertex to an anisotropic Gaussian kernel and uses a 3D CNN-GNN to predict per-vertex displacements and Cholesky-parameterized covariances from volumetric images. Training is guided by a covariance-aware negative log-likelihood loss with lightweight mesh regularization. For volumetric meshing, we warp a fixed tetrahedral template to the reconstructed surface via staged alignment, non-rigid registration, and deformation propagation, preserving connectivity and correspondence by construction, with resolution controlled by template density. Experiments show consistent gains over deformation-based baselines in surface mesh accuracy and volumetric mesh fidelity.

Penile measurement is clinically relevant across male reproductive and urogenital health, including conditions such as micropenis, congenital and endocrine disorders, and sexual or urinary dysfunction. However, quantitative assessment of penile size has relied mainly on external length or circumference measurements, which are difficult to standardize, sensitive to measurement conditions, and unable to capture the internal portion of the penis. MRI enables volumetric assessment of the whole penis in vivo, but automated segmentation has not previously been established at population scale. Automated whole-organ volumetry would enable high-throughput phenotyping for multi-omics and clinical studies of male reproductive disease. Here, we present a deep learning framework for whole-penis segmentation in multi-channel DIXON MRI. Using a newly curated expert-annotated training dataset ($n = 145$ subjects; $13,050$ annotated slices) and a double-annotated independent test benchmark ($n = 24$ subjects; $2,160$ double-annotated slices), we optimized a 3D nnU-Net architecture. The model achieved a 5-fold cross-validation Dice score of $0.90$ and performed at observer-level accuracy on the independent test set (Dice: $0.92$; Hausdorff distance: $3.58$). We deployed the model in $34,412$ UK Biobank participants, enabling automated quantification of total penile tissue, including both external and internal components. Longitudinal evaluation in 2,282 men demonstrated high inter-session reproducibility ($r = 0.87$). This framework establishes a reproducible and population-scalable method for MRI-based assessment of penile anatomy and provides an open technical resource for future studies in urological imaging and male reproductive health. The trained model weights will be publicly released.

We investigate volumetric reconstruction for compressive sensing light-sheet microscopy (CS-LSM), where fast volumetric imaging is achieved by encoding multiple axial planes into each camera exposure. To recover the underlying volume from highly multiplexed measurements, we propose a plug-and-play (PnP) framework that flexibly incorporates any user-specified denoiser into the reconstruction process. Building on a slice-based formulation, we further introduce an axial-coupled model that exploits correlations between adjacent slices to improve volumetric continuity. For efficient computation, we derive a Woodbury-based update for the data-consistency step in both the slice-based and axial-coupled formulations, and employ a Gauss-Seidel sweep for the denoising step in the axial-coupled model. Under a weakly convex regularization assumption, we establish subsequential convergence of the proposed algorithm. Experiments on synthetic and real zebrafish-heart data demonstrate that the proposed framework successfully recovers cellular structures from compressed measurements, and provide practical insights into the comparative performance of commonly used denoisers within the PnP framework under the CS-LSM setup.

Recent work has shown that implicit neural representations (INRs) can be trained to effectively compress structured and unstructured volume data, allowing for direct data querying with a reduced memory footprint. However, as existing INRs for unstructured volumes do not encode geometry, they require partial mesh storage for later sampling, limiting achievable compression. At the same time, novel view synthesis methods have shown that explicit collections of 3D Gaussians can be used to accurately visualize volume data. In this work, we introduce an explicit model for volume data compression based on 3D Gaussian primitives. We reinterpret collections of 3D Gaussians as an explicit representation of a scalar field and use a sampling strategy that reconstructs scalar values at spatial locations through weighted aggregation of intersecting Gaussians. We develop optimized CUDA-accelerated pipelines for structured and unstructured model sampling, loss functions that encourage accurate domain encoding by our models, and a novel sampling-error based densification strategy. Our explicit formulation naturally encodes domain geometry, eliminating the need for mesh storage in unstructured volumes and introducing significantly higher compression opportunities. Compared to existing INRs, we demonstrate that our explicit model achieves competitive reconstruction quality with significant training speedups on structured volumes, while markedly outperforming in all metrics on unstructured volumes.

Forest attributes are essential for national-scale resource monitoring. Airborne LiDAR metrics are among the auxiliary variables most strongly correlated with forest attributes used in National Forest Inventory (NFI) estimates. However, producing wall-to-wall predictions remains challenging when LiDAR data are acquired under heterogeneous conditions. As national LiDAR programs expand across Europe, variability in sensors, flight parameters, seasons, and scan angles limits the robustness of existing models, which are often calibrated for local conditions. We present FLORA (Forest LiDAR Octree Regression with Auxiliary Data), a deep learning framework that predicts six forest attributes: dominant height, total volume, deciduous volume, coniferous volume, basal area, and stem density from heterogeneous LiDAR point clouds. FLORA combines an octree-based backbone with ecological and spatiotemporal auxiliary variables through a late-fusion gating mechanism. Models are trained and evaluated on 32,052 National Forest Inventory plots across mainland France using data from the French LiDAR HD program. A single model trained on both leaf-on and leaf-off acquisitions outperforms season-specific models and improves cross-season robustness. Auxiliary variables provide modest overall gains but contribute more strongly to species-specific volume prediction. FLORA achieves an rRMSE of about 12.3% (R2 = 0.88) for dominant height and 39% (R2 = 0.74) for total volume, providing a robust baseline for large-scale forest attribute estimation from heterogeneous national LiDAR programs.

Despite rapid progress in learning-based stereo matching, high accuracy is often achieved at the cost of heavy backbones and computationally intensive 3D cost volume processing, resulting in substantial memory and runtime overhead. More critically, these methods frequently struggle to generalize across domains, limiting their practical deployment. We present \textit{LiteMatch}, a lightweight stereo matching framework that achieves strong zero-shot generalization through cost volume stabilization-without expensive 3D convolutions. LiteMatch employs two complementary encoders: a Cross-View Correspondence Encoder (CVCE) to capture global cross-view interactions, and a High-Frequency Encoder (HFE) that enhances fine structural details via FFT-based frequency cues. To stabilize the cost volume, we introduce the \textit{Cost Volume Consistency Loss (CVC-Loss)}, a voxel-wise binary cross-entropy objective applied to softmax-normalized cost distributions. By encouraging sharp and unimodal disparity probabilities, CVC-Loss promotes stable cost distributions and enables rapid convergence. A lightweight refinement module further produces sharp full-resolution disparities with low-iteration updates, avoiding heavy recurrent refinement. With a flexible design ranging from 3.36M to 9.58M parameters, LiteMatch achieves exceptional zero-shot generalization, delivering competitive EPE and D1 performance across Scene Flow, KITTI, Middlebury, ETH3D, and DrivingStereo. Our results establish that lightweight architectures can indeed generalize across domains without sacrificing accuracy. \href{https://mdraqibkhan.github.io/Litematch}{\textcolor{blue}{Code}}

Generating high-quality novel views at real-time frame rates remains a central challenge in 3D vision, particularly in sparse-view scenarios. Neural radiance fields have demonstrated robust reconstruction from limited observations, but their reliance on volumetric rendering leads to high computational cost and slow inference. In contrast, Gaussian Splatting methods achieve real-time rendering through rasterization, but their optimization is highly sensitive to the quality of the initial geometry. This sensitivity becomes especially problematic in sparse-view settings, where limited observations often lead to incomplete or noisy point-cloud reconstructions. In this work, we present AugSplat, a simple framework for improving Gaussian Splatting in sparse-view regimes using radiance-field-based view augmentation. We first train a radiance field on the sparse input views and use it to synthesize additional images from nearby novel viewpoints, increasing the effective view-space coverage available for supervision. These synthetic views are then used as auxiliary supervision during Gaussian Splatting optimization. We study two variants: Staged AugSplat, which uses synthetic views for an initial optimization phase before switching to real images, and Dual AugSplat, which jointly trains on real and synthetic views with a decaying synthetic loss weight. Experiments on sparse-view mip-NeRF 360 scenes show that AugSplat improves reconstruction quality over standard Gaussian Splatting. Staged AugSplat achieves the strongest average performance, while Dual AugSplat provides a closely performing formulation that keeps real-image supervision active throughout training, and both variants preserve real-time rendering at inference.

Modern deep neural networks often contain far more parameters than needed to fit their training data, yet they achieve impressive generalization. A common explanation for this success is the implicit bias of stochastic gradient descent (SGD). An alternative volume hypothesis posits that, within low training-loss regions, loss-landscape basins leading to strong generalization occupy much larger regions of weight space than basins that generalize poorly, and therefore SGD is simply more likely to land in the former. Recent experimental explorations of this idea present seemingly contradictory results. While in one set of experiments randomly sampling the network weights until achieving zero training error yielded poor generalization, molecular dynamics density estimates supported the volume hypothesis. We observe that these experiments were performed at different dataset size regimes, and explore an intermediate regime using the Replica Exchange Wang-Landau algorithm to estimate the joint density of states over training and test accuracies in binary networks. Across several architectures and datasets, we show that the generalization advantage of gradient learning over random sampling training generally diminishes as the training data size grows, suggesting a resolution of the paradox.

Camera-based 4D panoptic occupancy tracking (4D-POT) is a promising paradigm for holistic scene understanding from multi-view imagery, enabling joint reasoning about geometry, semantics, and object identities across time. Recent mask-based pipelines achieve strong performance by propagating instance queries across frames. However, their underlying volumetric representations are typically recomputed at each timestep, limiting geometric temporal consistency, particularly under occlusion and for static scene elements. To address this limitation, we propose a streaming Gaussian encoder that maintains a persistent volumetric scene representation for 4D-POT. Our method models the scene as a fixed-size set of latent Gaussian queries that are propagated via ego-motion compensation and refreshed under a confidence-guided budget constraint. Crucially, we shape Gaussian opacities through depth-based supervision to serve as proxy for visibility, enabling confidence to accumulate as a temporally aggregated measure of persistent scene support. Together with a warmup-based multi-frame training strategy, this yields representation-level temporal coherence beyond decoder-only tracking. Extensive experiments on Occ3D-extended nuScenes and Waymo establish a new state-of-the-art for camera-based 4D-POT, improving tracking consistency with negligible computational overhead while remaining fully compatible with existing mask-based pipelines. We provide code and models at https://sge.cs.uni-freiburg.de.

The continuous integral R2 indicator is a Pareto-compliant refinement of the classical finite-weight-vector R2 indicator, used in performance assessment, bounded archiving for a-posteriori multi-objective optimization, and skyline selection in databases. This work introduces a bidirectional perspective mapping between continuous integral R2 computation and integration over unions of anchored axis-aligned boxes. After translating the ideal point of a minimization problem to the origin, approximation points become strictly positive loss vectors, and the subgraph of the lower weighted Tchebycheff envelope over the weight simplex maps to the complement of an anchored-box union in reciprocal objective space. The Jacobian gives an absolute R2 formula as a weighted complement volume with density $(x_1+\cdots+x_N)^{-(N+1)}$, while differences of R2 values become finite weighted hypervolume differences. Hence, hypervolume algorithms that emit box decompositions can be reused by replacing ordinary box volumes with closed-form weighted box integrals. For $N$ objectives, this gives an output-sensitive overhead $O(2^N M)$ for an $M$-box decomposition, or $O(M)$ for fixed $N$. Using existing box-decomposition approaches, the integral R2 can be computed in $O(n \log n)$ for $N=2,3$, in $O(n^2)$ for $N=4$, and in $O\left(n^{\lfloor (N-1)/2\rfloor+1}\right)$ for $N\geq4$, with $n$ denoting the size of the approximation set. On the lower-bound side, exact value computation has an $Ω(n\log n)$ lower bound in the algebraic decision-tree model already in two objectives, this bound lifts to every fixed $N\geq2$, and exact computation is $\#P$-hard when $N$ is part of the input. Together, the proposed perspective mapping provides a powerful tool for transferring algorithmic and structural results between anchored-box union and hypervolume theory and integral R2 computation.

Volume microscopy, including electron and light microscopy, suffers from severe anisotropic resolution due to physical axial sectioning. Existing self-supervised axial super-resolution (ASR) methods face a trilemma bounded by overly smoothed regression textures, structural hallucinations of pure diffusion models, and prohibitive inference latency. In this paper, we propose Skeleton-refinE Microscopy (SkelEM), a self-supervised framework that decouples ASR at the training-signal level: a frozen topological network and a diffusion refiner are optimized by disjoint objectives, separating low-frequency topology formulation from high-frequency detail enhancement. Building on this deterministic skeleton, we exploit a unified cycle-consistent mechanism on input sparse slices to simultaneously extract a real-domain residual prior and bidirectionally align the diffusion refiner, washing away cross-plane artifacts without synthetic bias. By truncating the reverse diffusion process with this physical prior, SkelEM achieves high-fidelity detail restoration in merely $\le 5$ steps. To rigorously assess cross-instrument generalization, we further introduce BRAVE-ASR, a new benchmark of co-aligned anisotropic and isotropic volumes acquired on a Plasma-FIB instrument. Across public benchmarks, SkelEM achieves the most favorable balance across the fidelity-perception trade-off among self-supervised methods, with state-of-the-art downstream membrane segmentation performance and robust zero-shot generalization across distinct modalities.

Clinical machine learning increasingly relies on training corpora generated by large language models (LLMs) rather than annotated by clinicians, and such corpora are described and reused largely on the basis of their reported scale. We test whether volume reflects information content. Analysing the complete output of a multi-agent clinical extraction pipeline applied to 167,034 patient narratives, 2.51 billion generated tokens across the ten text-bearing channels of an eleven-channel pipeline, we introduce Provenance-based Redundancy Decomposition, a token-level classification of the entire output by source. Only 10.9% of the output is trainable-unique content while 79.4% is redundant; raw token count overstates information content by roughly ninefold. The redundancy arises through two distinct mechanisms, verbatim copying of source context into per-item fields, and duplication of generated text across records, of which only the former is losslessly removable. An independent, model-free analysis based on lossless compression confirms the redundancy, recovering the two mechanisms without reference to the provenance labels. One pipeline channel carries almost no redundancy, showing that the level of redundancy depends on how each channel is structured rather than being a fixed property of LLM extraction. Because uncorrected redundancy up-weights the longer, more complex presentations that generate the most items, it skews the token-level training distribution of the corpus, a property we measure directly. In a controlled downstream test, de-duplicating the corpus before adaptation improved a clinical encoder on external disease-recognition benchmarks at equal token budget, robustly across adaptation depths and replicated on a second benchmark, confirming that the redundancy carries a measurable cost beyond storage. The classification tool is released openly.

Uncalibrated volumetric video streaming for human reconstruction is essential for holographic communication and AR/VR, yet remains challenging due to the need for temporal consistency and computational efficiency from sparse-view inputs. Existing methods rely on per-scene optimization or calibrated cameras, while recent feed-forward models are limited to low-resolution (0.5K) single-frame synthesis. We present HiReFF, a feed-forward method for 2K-resolution 360° human video reconstruction from uncalibrated sparse-view videos. Our framework decomposes the problem into two key tasks: foreground 3D Gaussian reconstruction from sparse-view videos (four views separated by 90°) and computationally efficient high-resolution synthesis. To enable the former, we propose Scale-synchronized Camera Calibration to resolve scale ambiguity for multi-view supervision, and Gaussian-wise Foreground Masking to reconstruct clean foregrounds by modulating Gaussian parameters. For efficient high-resolution synthesis, our High-resolution Side-tuning achieves 2K rendering by augmenting the Gaussian head with supplementary features while keeping the backbone at 0.5K, drastically reducing computational overhead. Experiments demonstrate that HiReFF significantly outperforms existing methods in high-resolution streaming volumetric video reconstruction. https://iridescentjiang.github.io/HiReFF

We present a self-supervised framework for learning implicit 3D physical dynamics directly from video-derived supervisory signals. While current generative video models achieve high visual fidelity, they lack a 3D geometric foundation, often resulting in physical inconsistencies and a failure to maintain object permanence. We address this by shifting the predictive bottleneck from 2D image space to a `lifted' 3D Volumetric Latent Space. Our method unprojects semantic features from a Video Joint-Embedding Predictive Architecture (V-JEPA) into a voxelized grid, grounded by monocular depth priors. This lifting enables a Volumetric Feature Advection to learn an action-conditioned transition operator that treats physics as a spatio-temporal state advection problem, i.e., learn implicit 3D physics. Unlike state-of-the-art hybrid models that rely on explicit classical simulators for training and/or inference, our architecture tracks material states implicitly within high-dimensional V-JEPA features. This allows for the emergent simulation of heterogeneous phenomena (e.g., rigid body motion in fluid flow) within a single, unified pipeline. Supervised solely via end-to-end video-derived signal plus action conditions, without access to physics engine internal states, labels, or surrogate models, our model demonstrates good long-term structural stability and physical plausibility on multiple benchmarks (CLEVERER, PhysInOne, PhysGaia). We believe that this work opens a scalable pathway toward general-purpose dynamic world models that internalize the 3D invariants of the physical world solely through passive observation of monocular videos.

Self-supervised learning in fluorescence microscopy often relies on 2D projections, despite the inherently three-dimensional nature of cells. We present a systematic comparison of 2D and 3D masked autoencoders (MAE-2D vs. MAE-3D) on volumetric microscopy data. Under matched architectures and training protocols, MAE-3D consistently outperforms 2D max-projection and slice-based variants on downstream single-cell tasks. We further align visual representations with a pretrained protein language model (ESM2) and show that cross-modal supervision yields larger gains for volumetric models. Channel cross-attention and frequency-domain regularization are critical for leveraging 3D spatial context. On protein--protein interaction prediction, our best model achieves a ROC--AUC of 0.86, while on protein localization it reaches an AUC$_{\text{micro}}$ of 0.95 and an F1$_{\text{micro}}$ of 0.74, demonstrating competitive performance on both tasks. Overall, our findings highlight the potential of volumetric modeling and multimodal alignment for representation learning in single-cell microscopy.

Accurate volume and surface area estimation is critical for diverse applications, from marine ecology to medical diagnostics. However, existing methods often suffer from high computational costs and poor performance with sparse and noisy data. We propose a fully feed-forward framework that regresses scale-normalized volume and surface area and their associated uncertainties directly from multi-view images. By fusing 3D point cloud reconstructions with view-aligned 2D features through a graph-based decoder, our model bypasses iterative optimization, ensuring exceptional scalability and rapid inference. Experimental results demonstrate that our approach outperforms state-of-the-art methods, particularly when operating with a low number of input images. Validated across coral monitoring, dietary analysis, and anthropometry, our proposed framework provides a robust, adaptable solution for quantitative shape analysis. This architecture provides a high-speed, scalable alternative for precise geometric estimation from visual data, maintaining high performance even in resource-constrained or sparse-view scenarios.

We introduce VolHuMe, a dataset of high-quality 4D human scans captured with a state-of-the-art volumetric studio using 64 RGB and 32 depth cameras. VolHuMe contains individual captures of 104 subjects and provides extensive ground truth, including SMPL-X, high-resolution meshes, multi-view RGB/depth images, rigged meshes, point clouds, garment segmentation, and detailed hand and facial geometry. Unlike prior datasets that primarily rely on full-body imagery, VolHuMe uses a close-range, high-resolution capture setup that preserves fine-grained body-part details, improving geometric fidelity and texture resolution. We benchmark VolHuMe on state-of-the-art methods across 3D and 4D human reconstruction tasks, showcasing the dataset's quality and exposing the limitations of current evaluation testbeds.

Multi-view surface reconstruction is a core problem in computer vision. One prominent line of work represents the surface implicitly as a signed distance field (SDF), optimizing it based on the photometric loss between rendered and observed pixel colors. These approaches typically employ SDF-based volume rendering to obtain a differentiable relaxation of discontinuous visibility along rays, thereby reducing reliance on silhouette supervision. In this paper, we reformulate SDF-based volume rendering as probabilistic surface rendering, where each pixel color is modeled as a mixture distribution induced by the random first ray-surface intersection. To this end, we introduce Stochastic Signed Distance Processes (SSDP), which model the SDF along each ray as a stochastic process, inducing a first-passage-time distribution for each ray. We then derive the first-passage probability for each sampling interval based on Bayesian filtering, together with its practical approximation for parallel rendering. We further show that NeuS, an existing SDF-based volume rendering method, arises as a special case of our formulation. Experiments on the DTU and MobileBrick datasets demonstrate that our method outperforms baselines in both surface reconstruction and uncertainty quantification, supporting the effectiveness of our first-passage formulation. Our code is available at https://github.com/skmhrk1209/SSDP.

Generating large images via deep learning requires patching input data to accommodate hardware memory limitations, then assembling output patches, a process that can introduce stitching artifacts when neighboring patches do not align at borders. While these artifacts are known to affect segmentation tasks, their impact on generative models for style-transfer remains poorly understood. We investigated three stitching approaches and two patch dimensionalities (2D vs 3D) using cycleGAN models trained on cryo-electron microscopy datasets. We evaluated both perceptual quality and performance on downstream mitochondria segmentation. Our key findings reveal that: (1) FID scores fail to detect subtle stitching artifacts that significantly impact downstream segmentation performance, (2) 3D models with artifact-free stitching marginally outperform 2D models on downstream tasks, though the improvement barely justifies the computational cost, and (3) 2D models train more stably due to larger batch sizes. Additionally, we demonstrate that ensembling predictions from three orthogonal directions can improve low-quality volumes but provides no benefit for high-quality outputs. These results demonstrate that maximizing generative model performance on large scientific datasets requires careful consideration and mitigation of stitching artifacts, and that perceptual metrics alone are insufficient for evaluating domain adaptation quality in biomedical imaging.

Recently neural implicit rendering techniques have evolved rapidly and demonstrated significant advantages in novel view synthesis and 3D scene reconstruction. However, existing neural rendering methods for editing purposes offer limited functionalities, e.g., rigid transformation and category-specific editing. In this paper, we present a novel mesh-based representation by encoding the neural radiance field with disentangled geometry, texture, and semantic codes on mesh vertices, which empowers a set of efficient and comprehensive editing functionalities, including mesh-guided geometry editing, designated texture editing with texture swapping, filling and painting operations, and semantic-guided editing. To this end, we develop several techniques including a novel local space parameterization to enhance rendering quality and training stability, a learnable modification color on vertex to improve the fidelity of texture editing, a spatial-aware optimization strategy to realize precise texture editing, and a semantic-aided region selection to ease the laborious annotation of implicit field editing. Extensive experiments and editing examples on both real and synthetic datasets demonstrate the superiority of our method on representation quality and editing ability. Project page: https://zju3dv.github.io/neumeshplusplus/

Although DINOv3 has demonstrated remarkable semantic discrimination in natural imagery, its direct application to volumetric medical segmentation is hindered by inherent dimension and domain disparities. To resolve these issues, we propose DINO-Med3D, a two-stage progressive framework that repurpose the pre-trained DINOv3 encoder for 3D medical tasks. In the first stage, we mitigate the dimension gap by introducing a multi-slice embedding module that incorporates pseudo-3D context, while simultaneously employing a segmentation proxy task to adapt representations learned from natural scenes to the medical domain. Subsequently, we further enhance volumetric understanding by adding lightweight 3D adapters into the frozen backbone to enforce global inter-slice continuity. Finally, to compensate for the spatial information loss inherent in the embedding process, we design a parallel detail recovery stream to explicitly preserve high-frequency boundary cues. Extensive experiments on five public datasets demonstrate that our approach successfully adapts DINOv3 to the medical domain and significantly outperforms state-of-the-art baselines.

Accurate mechanical properties (or materials) Young's modulus ($E$), Poisson's ratio ($ν$) and density ($ρ$) are essential for reliable physics simulation of digital worlds, but most 3D assets lack this information. We propose AdaVoMP, a method for predicting accurate dense spatially-varying ($E$, $ν$, $ρ$) for input 3D objects across representations, improving the resolution, accuracy, and memory efficiency over the state-of-the-art. The foundation of our technique is a sparse and adaptive voxel structure SAV that efficiently represents both the input 3D shape and the material field output. We replace the fixed-voxel model of the most accurate prior method, VoMP, with a novel sparse transformer encoder-decoder model that learns to generate a unique SAV autoregressively for every input shape to represent its materials, achieving a resolution $16^3\times$ higher than prior art. Experiments show that AdaVoMP estimates more accurate volumetric properties, even with lesser test-time compute than all prior art. This allows us to convert high-resolution complex 3D objects into simulation-ready assets, resulting in realistic deformable simulations.

This paper introduces a new methodology for real-time prediction of ergonomic and non-ergonomic human poses using volumetric video data in three dimensions. Although the methodology was designed for ergonomic assessments, it can be adapted to other applications requiring real-time analysis of human posture. One aspect that makes this system stand out is its ability to analyze 3D point clouds during the assessment, enabling computation from multiple angles. This overcomes a critical limitation of cameras which provide often a fixed viewpoint, thereby restricting the data available for a thorough postural evaluation, especially when occlusions occur. The system continuously and automatically performs pose inference using the chosen perspective on the real-time streaming data; however, only the poses manually selected and labeled by the user are used to train the personalized deep learning classifier. The methodology has been refined through a case study in which RGB-D cameras captured subjects performing load-lifting tasks, enabling real-time skeletal labeling. The model was trained on this data and, following the training phase, performs inference on new streaming data in real time. This research offers a scalable and pragmatic approach for real-time ergonomic evaluation by combining state-of-the-art 3D data technologies and traditional 2D pose estimation algorithms. It addresses the increasing need for safety and health monitoring in workplace environments, marking a notable contribution to the domain.

Facial hair is a defining trait of personal identity, yet remains a critical bottleneck for digital avatars. Recent volumetric methods achieve photorealism but bake hair into the underlying face geometry, preventing editability and failing to resolve sparse, strand-like structures. Meanwhile, scalp-hair reconstruction methods target dense hair volumes and do not transfer to the sparse, spatially-varying nature of facial hair. We present a pipeline that automatically reconstructs facial hair -- beard, mustache, lashes, and brows -- from multi-view images, converting an unstructured 3D Gaussian representation into an explicit curve-based strand representation. We resolve geometric ambiguities in four stages: (i) optimizing 3D Gaussians constrained by tracked head geometry to enforce early ray termination and suppress sub-surface noise; (ii) tracing continuous strands robust to frequent crossings and extreme curvature; (iii) grounding strands to the surface and resolving root-tip ambiguity via a physically-motivated prior; and (iv) refining the reconstruction through opacity-driven density control under photometric optimization. To our knowledge, this is the first method to reconstruct high-fidelity facial hair strands from a 3D Gaussian representation. The recovered strands faithfully preserve the orientation and sparsity patterns characteristic of facial hair, and yield assets immediately suitable for downstream production tasks, including facial animation and physical simulation, geometric grooming and transfer, appearance editing, and physics-based rendering.

Self-supervised learning has enabled large-scale pre-training on 2D natural images, producing general-purpose visual representations that transfer effectively across tasks. However, many medical imaging modalities, such as CT scans, are inherently three-dimensional and differ fundamentally from natural images in both structure and semantics. Volumetric modalities capture spatial continuity, organ anatomy, and intensity-based tissue properties (e.g., Hounsfield Units), which are not adequately modeled by 2D pre-training. To bridge this gap, we introduce CoralBay, a self-distillation framework that extends DINO by using a hierarchical 3D Swin backbone and applying self-distillation to concatenated multi-scale features, enabling data-efficient self-supervised learning of rich spatial representations that encode both global semantics and fine-grained local structure. As a result, CoralBay transfers effectively to a wide range of downstream radiological tasks, demonstrating strong and consistent performance across diverse anatomical targets. In addition, we contribute to the open-source \eva framework by introducing a public, reproducible 3D radiology leaderboard that unifies multiple datasets and establishes a standardized benchmark for evaluating volumetric representation learning methods.

Can a visually plausible food mesh be trusted to estimate the volume of consumed food? \method investigates this question using selected paired before- and after-consumption states from the MetaFood CVPR 2026 Continuous 3D Reconstruction While Eating Challenge. The submitted workflow follows a curated reconstruction protocol: SAM3 segments the food and plate regions; Hunyuan3D/SAM3D generates a dimensionless food mesh; the plate diameter provides the metric scale; the plate geometry is removed in Blender; and the remaining mesh is hole-filled, made watertight, and integrated to estimate volume. MoGe-2 is used only as an auxiliary cue for initial dish-diameter estimation when direct plate measurement is uncertain; it is not the primary scale source for the reported challenge result. \method ranks first, with an average Chamfer distance of 8.31 across 34 meshes using rigid ICP without scale correction. On 17 before- and after-pairs, it achieves 33.87% state-level volume MAPE and zero monotonicity violations, while consumed-volume MAPE remains 53.74%. The results show that surface reconstruction, metric scale, controlled mesh cleanup, watertight volume integration, and physical depletion consistency should be evaluated separately for dietary assessment. Source code and evaluation scripts will be available at \href{https://github.com/GCVCG/PerBite-CVPR-MetaFood-2026}{github.com/GCVCG/PerBite-CVPR-MetaFood-2026}.

Dense volumetric reconstruction of cloud microphysical fields from sparse ground-based instruments remains an open problem, largely because the available measurements are heterogeneous in both modality and spatial coverage. We present AtmoFuseNet, a framework that fuses multi-view sky camera imagery with millimeter-wave cloud radar and ceilometer observations to produce 4D (three spatial dimensions plus time) estimates of cloud state and wind. The method operates in three stages: a cross-modal hierarchical aggregation module that combines image feature pyramids with instrument-derived vertical profiles through layer-wise cross-attention; a conditional variational refinement module that maps the resulting volume to physically consistent microphysical fields under differentiable radar and image forward models; and a correlation-based motion estimator that recovers per-voxel 3D wind vectors from consecutive volumetric reconstructions. On collocated observations from a semi-arid site, AtmoFuseNet reaches 0.026 g m^-3 liquid water content MAE and 1.18 m s^-1 wind speed MAE, improving over existing retrieval baselines. Ablation experiments isolate the contribution of each module.

Learning transferable and interpretable representations from medical volumetric scans remains challenging due to complex anatomical structures and weak, heterogeneous supervision provided by radiology reports. In this paper, we propose Anatomy-aware Semantically-Adaptive Pre-training (ASAP), a principled vision-language pre-training framework for fine-grained medical volumetric representation learning from large-scale chest CT scans and their corresponding radiology reports. ASAP integrates three key components: (1) an anatomy-aware knowledge injection module that incorporates organ-level structural priors via off-the-shelf segmentation tool to encourage anatomically coherent representations; (2) a semantically-adaptive selective alignment mechanism that dynamically associates sentence-level findings with localized volumetric regions; and (3) a semantically-adaptive fusion module for effective interaction between anatomically informed visual features and grounded textual cues under dual-modal masked modeling paradigm. Beyond methodological contributions, we establish a comprehensive benchmark for medical volumetric vision-language pre-training on chest CT, covering 15 datasets and 22 downstream tasks spanning abnormality classification, segmentation, disease prognosis prediction, report generation, vocabulary classification, cross-modal retrieval and visual question answering. This benchmark provides standardized evaluation protocols to systematically assess representation quality under diverse clinical settings and data regimes. Extensive experiments demonstrate that ASAP consistently achieves state-of-the-art performance across tasks and datasets, with particularly pronounced gains under limited supervision and distribution shift, validating its effectiveness in learning transferable and clinically meaningful volumetric representations.

Reconstructing the complete geometry of a scene from a single RGB image remains challenging - especially when inferring hidden structures where visual evidence is incomplete. We introduce VolFill, a generative framework that predicts the 3D structure of the complete scene rather than relying on traditional pixel-aligned regression. Our method utilizes a hybrid 3D VAE to compress sparse truncated unsigned distance function grids into a compact latent space, paired with a latent Diffusion Transformer that denoises this representation to recover the complete scene. We condition the generation on geometry foundation models, leveraging rich spatial priors for robust reasoning. Unlike existing methods limited by per-ray constraints or unstructured point-cloud queries, VolFill provides a structured representation that supports direct surface extraction and occupancy queries at scale. Extensive experiments on the SCRREAM and NRGB-D datasets demonstrate that our approach significantly outperforms current baselines, providing a robust foundation for holistic spatial understanding.

With the emergence of wireless applications in three-dimensional environments, such as the low-altitude airspace and 3D heterogeneous networks, radio map estimation is increasingly required to characterize signal propagation across both horizontal and vertical dimensions. However, extending radio map estimation from 2D to 3D remains challenging due to increased spatial sparsity and limited supervision across continuous altitudes. In this paper, we propose \textbf{\textit{RadioFormer3D}}, a specialized model for volumetric spectrum reconstruction under weak supervision. Building on the dual-stream, multi-granularity fusion architecture of \textit{RadioFormer}, \textit{RadioFormer3D} introduces a Fourier-based sampling encoder and a volumetric decoder to efficiently process sparse measurements in 3D space. To alleviate the lack of vertical supervision, we propose the \textbf{\textit{Joint Spectrum Integrity Loss}}, which integrates volume-level pseudo-label supervision, map-level geometry-aware radio rendering, and pixel-level localized constraints within a unified optimization scheme. This design enables the model to capture complex vertical structural relationships more effectively under sparse supervision. Extensive experiments across several radio map datasets show that \textit{RadioFormer3D} achieves superior overall performance compared to representative existing methods. In particular, it demonstrates improved reconstruction quality at unlabeled altitudes while maintaining a favorable trade-off between accuracy and inference efficiency, positioning it as a highly promising solution for future 3D environment-aware wireless networks.

We introduce a probabilistic splat-based radiance field framework that retains the fast rasterization and test-time efficiency of 3D Gaussian Splatting (3DGS) while replacing heuristic primitive manipulation with gradient-based optimization of a volumetric probability density. Rather than relocating, splitting, or culling Gaussians via hand-tuned densification (e.g., ADC), we treat primitive locations as samples drawn from a persistent, learnable density. We instantiate this density using a novel, memory-efficient multi-scale hierarchical grid that enables end-to-end gradient-based optimization. To stabilize the optimization, we derive an unbiased gradient estimator with control variates that markedly reduces variance. By allowing probability mass to flow to where the loss demands, our framework eliminates brittle priors and naturally explores the volume, achieving state-of-the-art reconstruction quality on mip-NeRF 360 while preserving 3DGS-level rendering speed.