Multi-Agent LLM Systems

LLM: Large Language Model

Momentum

85 papers in the last four weeks, up 107% on the four weeks before. 0.8% of all new papers.

Jul 13Week of Sep 28

Latest papers 668

May 28, 2026cs.AI

AgentSchool: An LLM-Powered Multi-Agent Simulation for Education

Despite the rapid deployment of LLMs into classrooms, validating educational AI remains uniquely intractable: interventions act on developing learners whose cognitive and social trajectories are irreversibly shaped, while real-world trials are slow, ethically constrained, and institutionally locked. LLM-based educational simulators have emerged as a potential remedy, but many still collapse learning into persona-conditioned role-play and, when optimized only to reproduce existing classrooms, can structurally penalize the institutional novelty that pedagogical reform requires. In this work, we introduce AgentSchool, an LLM-driven multi-agent simulator that models learning as state transition rather than prompted behavior. AgentSchool couples cognitively growable student agents -- equipped with weighted subject knowledge graphs, thinking-workflow pools, and explicit misconceptions -- with adaptive teacher agents that plan, scaffold, and reflect along the Zone of Proximal Development, embedded in a configurable scenery generator that situates instruction within both formal and informal learning fields, and a multi-scale simulator that decouples interaction scale, temporal granularity, and simulation duration. Experiments show that structured student agents produce more differentiated mastery and misconception traces than a baseline simulator, while teacher-agent comparisons show backbone-dependent patterns consistent with ZPD-informed adaptation. Further, AgentSchool generates plausible traces of peripheral participation, clique formation, aggressor-induced cohesion, and opinion-leader emergence consistent with classroom social theories. Beyond its role as an educational research instrument, AgentSchool frames education as a socially meaningful testbed for long-horizon memory, multi-agent coordination, and future institutional reasoning under organizational pressure.
May 28, 2026cs.AI

Enhancing Multi-Agent Communication through Attention Steering with Context Relevance

LLM-based multi-agent systems have demonstrated remarkable performance on complex tasks through collaborative reasoning. However, these systems tend to rapidly accumulate extremely long conversation histories during interaction. As conversations lengthen, relevant information is increasingly diluted by irrelevant context, leading to degraded performance. In this work, we present Agent-Radar, a training-free context management method that dynamically steers each agent's attention toward relevant context with a novel temporal and spatial decay mechanism. Our experiments demonstrate that Agent-Radar outperforms state-of-the-art methods across five different benchmarks, yielding gains of up to 7.64 absolute points. Furthermore, our analysis shows that Agent-Radar remains effective and robust as the number of agents and interaction rounds increases. Finally, the ablation study shows that core components in Agent-Radar are crucial to performance and generalizable in different settings.
May 28, 2026cs.MA

When Cloud Agents Meet Device Agents: Lessons from Hybrid Multi-Agent Systems

The design space of agentic AI inference spans two extremes: frontier large language models (LLMs), typically hosted in the cloud and offering strong performance across a wide range of tasks at substantially high cost, and more cost-efficient small language models (SLMs), which are amenable to on-device inference. Hybrid multi-agent systems (MASs) combining on-device and cloud models offer a promising middle ground, but they also introduce a complex and poorly understood design space in which task accuracy, monetary cost, and edge energy consumption are tightly coupled; in the absence of general design principles, hybrid components, although not the most prevalent choice, are typically introduced through ad hoc decisions tailored to specific domains. In this work, we examine this design space more systematically. We adapt two representative MAS architectures to support hybrid inference and study how individual design choices shift the operating point along the Pareto frontier of power, cost, and performance. Our findings paint a nuanced picture of hybrid MAS design: while SLMs can effectively benefit from LLM assistance, the optimal architecture is highly task-dependent, and greater frontier-level compute does not consistently translate to better performance.
May 28, 2026cs.AI

Learning to Choose: An Empowerment-Guided Multi-Agent System with semantic communication for Adaptive Method Selection

Automating scientific computing workflows requires more than generating executable code: autonomous systems must also select appropriate computational strategies, implement them faithfully, and ensure that the resulting outcomes remain causally attributable to the decisions that produced them. In multi-agent pipelines, this process is particularly fragile, as small inconsistencies between agent intentions and actions can lead to semantic drift, where the eventually executed procedure no longer reflects the originally selected strategy, thereby corrupting downstream evaluation and adaptation. In this work, motivated by the ATHENA framework (Toscano et al., 2025; Toscano et al., 2026) and the concept of empowerment (Yiu et al., 2025), we introduce a multi-agent framework that combines contextual bandits with structured inter-agent communication and, most importantly, semantic checkpoints that preserve action-outcome fidelity throughout the pipeline. The system integrates specialized large language model (LLM) agents, grounded code generation, and self-healing execution loops within an adaptive decision-making architecture. Interpreting the framework through the lens of empowerment, we show that reliable autonomous learning requires not only identifying high-quality actions, but also preserving the integrity of their propagation across agents. Using sensitivity analysis and uncertainty quantification workflows as representative case studies, we demonstrate that unchecked semantic drift degrades policy learning, whereas the proposed framework improves convergence, robustness, and adaptation to novel problem contexts. These results suggest a broader design principle for scientific multi-agent systems: adaptive decision-making must be coupled with explicit mechanisms that guarantee semantic consistency and reliable information flow across the computational pipeline.
May 28, 2026cs.SE

Agora: Toward Autonomous Bug Detection in Production-Level Consensus Protocols with LLM Agents

Consensus protocols form the backbone of distributed systems and blockchains, where implementation bugs can cause data corruption and financial losses. While LLM-based approaches show promise in code analysis, they struggle with deep protocol-level logic bugs involving complex state-dependent behaviors across multiple execution stages. We present Agora, a domain-aware multi-agent framework that integrates hypothesis-driven testing with LLM capabilities for systematic protocol verification. Agora employs specialized agents that collaboratively explore protocol state spaces, synthesize attack scenarios using domain-specific constraints, and validate findings through iterative refinement. This explicit role separation enables reasoning about global protocol invariants beyond single-function code analysis. We evaluate Agora on four consensus implementations (Raft, EPaxos, HotStuff, BullShark) using four state-of-the-art LLMs. Agora discovers 15 previously unknown protocol-level logic bugs that violate safety properties, while existing LLM-based agents fail to detect any such protocol-level logic bugs. Our results demonstrate that domain-aware multi-agent collaboration is essential for detecting deep logic bugs in complex protocols.
May 28, 2026cs.MA

Evolutionary Dynamics of Cooperation in Next-Generation LLM Agent Systems: A Cross-Provider Empirical Extension

Do next-generation LLM agents inherit the cooperative biases documented in their predecessors, or does scale and provider diversity reshape equilibrium behaviour in competitive multi-agent settings? Willis et al. established a benchmark for this question using evolutionary game theory and the Iterated Prisoner's Dilemma (IPD), finding consistent cooperative biases in ChatGPT-4o and Claude 3.5 Sonnet. We extend this benchmark to four frontier models released in 2025-2026 - Claude Sonnet 4.6, Gemini 2.5 Flash, Gemini 3.1 Pro, and GPT-5.4 Mini - applying the identical protocol across three prompting styles (Default, Prose, Self-Refine) and four population compositions (balanced and biased, with and without noise). Cooperative bias persists across providers (H1): ten of twelve model-prompt combinations favour cooperative equilibria in balanced noiseless conditions. Cross-provider divergence is substantial (H3): Gemini 2.5 Flash reaches up to 77% aggressive equilibria under biased conditions, while GPT-5.4 Mini reaches 70% cooperative equilibria under Self-Refine. Support for aggressive capability parity is partial (H2): Self-Refine raises ICD in all models and Gemini 3.1 Pro Refine achieves the highest ICD in the dataset (0.925), but Default and Prose prompts show no systematic narrowing. Evidence on noise robustness is directionally positive but not robustly confirmed (H4): with n=500 Moran iterations per condition, average noise sensitivity is about 6 percentage points for Claude Sonnet 4.6 versus 13 pp for Claude 3.5 Sonnet, but this cross-study gap is not statistically significant once the predecessor's unreported sampling error is propagated. Provider identity, rather than model generation, is the strongest correlate of equilibrium outcomes; noise remains a universal challenge regardless of model size or vintage.
May 28, 2026cs.AI

Why Specialist Models Still Matter: A Heterogeneous Multi-Agent Paradigm for Medical Artificial Intelligence

The impressive performance of generalist large language models (LLMs) such as GPT and Claude in healthcare raises a critical question: will domain-specific medical specialist models become obsolete? We argue that the future of medical artificial intelligence (AI) lies not in building monolithic medical foundation models, nor in replacing human expertise, but in orchestrating collaboration among generalist LLMs, domain-specific specialist models, and clinicians. We propose HetMedAgent, a heterogeneous medical multi-agent framework that enables conflict-aware evidence fusion, uncertainty-based clinician intervention triggering, and adaptive threshold calibration. Experiments on three real-world clinical decision-making tasks demonstrate that the synergy between generalist LLMs and domain-specific specialist models significantly outperforms using either type of model alone, validating the irreplaceable value of specialist models in modality-specific analysis. HetMedAgent represents a shift from building medical LLMs or foundation models to multi-agent collaboration, achieving a balance between general reasoning capabilities and domain-specific precision.
May 28, 2026cs.AI

Improving Collaborative Storytelling with a Multi-Agent Framework Based on Large Language Models

The topic of Co-creation, i.e., AI agents interacting with humans to generate outputs (e.g., art), has gained significant attention recently. However, most studies focus on adult-human interactions in a digital setting. This paper explores a novel ludic co-creation scenario involving children and Large Language Models (LLMs) interacting through a physical board game to create written stories. Our goal is to develop a multi-agent framework capable of producing high-quality narratives suitable for young players. At the core of our approach is an iterative Writer-Editor process in which one LLM generates stories while another evaluates them and provides feedback for refinement. Through a simulation study involving multiple LLMs, we show that this iterative interaction consistently improves the perceived quality of generated stories across successive loops. The results indicate that a small number of refinement steps may be sufficient to achieve high-quality outputs in interactive storytelling systems.
May 28, 2026cs.MA

DynaGraph: Lightweight Multi-Model Interaction Framework via Dynamic Topological Reconfiguration

Tackling complex reasoning tasks typically relies on massive monolithic LLMs, which suffer from severe computational redundancy. While task decomposition through structured pipelines or multi-agent collaborations offers an alternative, these approaches inevitably fall into a critical dilemma: predefined static topologies are highly vulnerable to cascading errors, whereas unconstrained dynamic agents suffer from trajectory divergence and unpredictable memory bloat. To address this, we present DynaGraph, a lightweight multi-model framework driven by dynamic topological reconfiguration. At the execution level, DynaGraph multiplexes time-division PEFT adapters over a shared base model, enabling both full system training and inference deployment on a single consumer-grade GPU. At the routing level, the Evaluator continuously monitors execution confidence to trigger hierarchical self-healing: Fine-grained Patching for localized data gaps and Subgraph Reconstruction for severe logical ruptures. Experiments on StrategyQA, MATH, and FinQA demonstrate our 8B model closely approximates the reasoning capabilities of a 72B monolithic model (e.g., 87.6% on StrategyQA, 82.7% on MATH). Furthermore, it reduces latency by up to 68.1% and token consumption by 68.6% compared to unconstrained dynamic architectures.
May 28, 2026cs.CL

SURGENT: A Surgical Multi-Agent Assistance System Across the Perioperative Workflow

The intricate nature of modern surgical care necessitates intelligent systems that can synthesize extensive patient records, support collaborative decision-making, and provide transparent, auditable reasoning across the entire perioperative workflow. Although web-based Large Language Models (LLMs) possess advanced reasoning capabilities, they are ill-equipped for surgical applications due to critical limitations: input length constraints, incomplete memory management, and limited traceability. To address this issue, we present SURGENT, a surgical multi-agent assistance system that combines a Tree-of-Thought planner, multi-department collaboration agents, and retrieval-augmented reasoning with clinical guidelines and biomedical literature. SURGENT features a novel memory design that manages both long-term patient histories and short-term working summaries, enabling more complete, contextualized, and consistent reasoning. Experimental evaluations across five key perioperative tasks - case analysis, surgical plan simulation, safety monitoring, complication risk assessment, and rehabilitation guidance - show that SURGENT outperforms baseline LLMs and existing medical multi-agent frameworks, yielding recommendations more closely aligned with patient histories. Ablation studies further highlight the advantage of DeepSeek as a locally deployable backbone model, enabling privacy-preserving deployment without reliance on centralized services. These results position SURGENT as a practical and trustworthy advancement toward intelligent, equitable, and secure surgical assistance systems.
May 28, 2026cs.CL

PatchBoard: Schema-Grounded State Mutation for Reliable and Auditable LLM Multi-Agent Collaboration

LLM multi-agent systems often coordinate through natural-language dialogue or loosely structured shared memory, making intermediate state difficult to validate, attribute, and audit. We introduce PatchBoard, a schema-grounded collaboration architecture that replaces inter-agent dialogue with validated JSON Patch mutations over a shared structured state. An Architect agent constructs a task-specific schema and workflow rules, while a deterministic kernel validates each proposed state mutation against schema constraints, role-specific write contracts, and runtime invariants before committing it transactionally. On 630 matched ALFWorld episodes, PatchBoard achieves an 84.6% success rate, compared with 30.8% for LangGraph and 61.6% for Flock, while reducing tokens per successful task to 45.5k, compared with 368.3k and 64.2k, respectively.
May 27, 2026cs.CL

SafeRx-Agent: A Knowledge-Grounded Multi-Agent Framework for Safe and Explainable Medication Recommendation

Medication recommendation predicts medications for patient visits, but existing methods still face two key challenges. At the model level, traditional drug recommendation methods only predict structured drug codes with limited evidence grounding, while LLM agents can use richer clinical context but may lack safety verification and traceability. At the task level, existing benchmarks often use broad medication categories, which ignore subgroup-level safety differences and can lead to risk overestimation. We introduce the first fine-grained medication recommendation setting based on fourth-level ATC code generation. We propose Safe Prescription Agent (SafeRx-Agent), a knowledge-grounded multi-agent framework that uses patient context, external clinical knowledge, and safety verification to recommend traceable medication sets. Experimental results on MIMIC-III and MIMIC-IV datasets show that SafeRx-Agent improves fine-grained medication prediction accuracy while controlling drug interactions, contraindications, and medication set size.
May 27, 2026cs.CL

Bosses, Kings, and the Commons: Cooperation Under Power Asymmetry in LLM Societies

Communities can sustainably manage shared resources (commons) through self-governance and cooperative norms, a central finding of Ostrom's theory of self-governance. However, real-world commons (e.g., fisheries, forests, and irrigation systems) are often governed under asymmetric power structures, where certain individuals or institutions possess disproportionate control over resource extraction and collective outcomes. As Large Language Models (LLMs) are increasingly explored as agents in synthetic governance simulations, understanding how LLM societies behave under asymmetric power structures is becoming increasingly important, yet existing evaluations largely ignore such asymmetries. We introduce Sovereignty over the Commons Simulation (SovSim), a generative multi-agent simulation framework that incorporates an agent with asymmetric power (boss or king) into a society of symmetric agents (workers or peasants), where all agents extract from a shared resource, collectively determining its sustainability over time. Across eleven state-of-the-art models, we find that introducing asymmetric power leads to severe breakdowns in cooperation and sustainability, with up to an 87.3% degradation in survival rate relative to symmetric settings.
May 27, 2026cs.AI

Hallucination Mitigation with Agentic AI, Nested Learning, and AI Sustainability via Semantic Caching

Hallucination remains a major reliability barrier for production LLM systems, particularly in multi-agent pipelines where unsupported claims can propagate unchecked across stages. This paper adapts a HOPE-inspired Nested Learning architecture with Continuum Memory Systems (CMS) and semantic similarity caching to a hybrid benchmark of 310 prompts combining 217 epistemic-uncertainty prompts and 93 fabrication-induction stress-test prompts. A three-stage agentic pipeline orchestrated via the Open Floor Protocol (OFP) is evaluated with five KPIs -- FCD (Factual Claim Density), FGR (Factual Grounding References), FDF (Fictional Disclaimer Frequency), ECS (Explicit Contextualization Score), and OSR (Observability Score Ratio) -- aggregated into THS (Total Hallucination Score) across five weighting configurations to study mitigation-observability trade-offs. FDF, ECS, OSR, and FGR are subtracted as mitigation signals, so that a more negative THS indicates stronger mitigation. The FrontEndAgent is configured as a high-stochasticity generator (temperature = 1.0) to produce a realistic hallucination baseline, while the SecondLevelReviewer and ThirdLevelReviewer operate as progressive correctors. This asymmetric design yields end-to-end THS reductions of -31.3% to -35.9% across five weighting configurations. Semantic caching achieves 440 cache hits over 930 potential calls (47.3% hit rate), reducing LLM invocations to 490, lowering energy and CO2e footprint, and making multi-stage review pipelines operationally viable at production scale. ExtremeObservability attains the most negative final THS (-0.0709), confirming that observability-heavy configurations reinforce rather than compromise mitigation. These findings suggest that memory-augmented multi-agent designs can jointly improve factual reliability, operational efficiency, and auditability without model retraining.
May 27, 2026cs.CL

Roles with Rails: Contract-Preserving Role Evolution in Multi-Agent Structured Reasoning

Role-based LLM multi-agent systems need adaptive role pools, yet adapting such systems is not merely a matter of prompt optimization: roles often carry structural obligations, including capability coverage, message compatibility, validation, final-answer aggregation, and parser-compatible output protocols. Existing systems either fix the role inventory and lose adaptivity, or allow unconstrained generation to induce role drift, removing structurally necessary roles and breaking answer contracts. We formulate this as contract-preserving role evolution, requiring every committed edit to preserve five structural contracts (capability, communication, validation, aggregation, output protocol). We instantiate this formulation in SERO, a Self-Evolving Role Orchestration framework that evolves a typed role-card pool through credit-guided retrieval, a credit-ranked communication DAG with a protected terminal aggregator and conditional validator repair, and a contextual-bandit controller whose LLM-proposed edits are committed only when they preserve the contracts and improve task score. Experiments on real-world reasoning benchmarks across three LLM backbones confirm the value of contract-preserving role evolution.
May 27, 2026cs.CR

Out of Sight, Not Out of Mind: Unveiling Latent Attack in Latent-based Multi-Agent Systems

Latent-based multi-agent systems replace parts of explicit inter-agent communication with hidden representations, offering a new direction for efficient and flexible agent collaboration. However, moving coordination into latent space may also move attacks beyond the reach of visible-text inspection. In this paper, we study whether latent states can carry attack-associated information that remains effective during clean executions. To examine this question, we introduce a latent attack framework that reactivates attack-induced effects through latent interventions without reusing adversarial text. Extensive experiments show that the resulting latent-only attacks can substantially degrade task performance in clean executions, especially when applied to inter-agent KV-cache handoffs rather than local hidden states. Further control analyses indicate that this degradation cannot be reduced to arbitrary perturbations or invalid generation. Overall, our findings suggest that latent-based collaboration does not remove attack risk. It shifts part of the risk into less observable execution states, calling for safeguards beyond visible-text inspection.
May 27, 2026cs.CL

LegalGraphRAG: Multi-Agent Graph Retrieval-Augmented Generation for Reliable Legal Reasoning

Graph-based Retrieval-Augmented Generation (GraphRAG) advances flat document retrieval by structuring knowledge as relational graphs, enabling more coherent and effective reasoning. However, applying it to specific domains like legal reasoning faces critical challenges. (i) Legal corpora are heterogeneous, containing multi-granular knowledge from cases, articles and interpretations. A flat knowledge graph cannot adequately differentiate between factual details, applied rules, and abstract principles, limiting accurate retrieval. (ii) Reliable legal judgment demands transparent, evidence-based reasoning. Traditional RAG passes retrieved context directly to an LLM without verification, resulting in opaque, error-prone reasoning. To this end, we propose LegalGraphRAG, a framework designed for reliable legal reasoning. Our approach introduces two core components: a hierarchical legal graph that hierarchically organizes legal sources to enable retrieval at appropriate abstraction levels, and a multi-agent system for reliable legal reasoning, where a Researcher retrieves candidate evidence, an Auditor rigorously verifies its validity against source documents, and an Adjudicator synthesizes the set of verified evidence to render a final judgment. Extensive experiments show that LegalGraphRAG achieves the state-of-the-art performance, outperforming existing GraphRAG baselines in accurate and trustworthy legal analysis. Our code, datasets and implementation details are available at https://github.com/XMUDeepLIT/LegalGraphRAG.
May 27, 2026cs.AI

Defending LLM-based Multi-Agent Systems Against Cooperative Attacks with Sentence-Level Rectification

Recent years have witnessed the rapid development of Large Language Model-based Multi-Agent Systems (MAS), which excel at collaborative decision-making and complex problem-solving. However, malicious agents in MAS may inject misinformation to mislead other agents and disrupt system performance, giving rise to a new research direction that focuses on attack mechanisms and defense strategies in MAS. Prior studies largely assume malicious agents act independently and investigate the corresponding defense strategies. However, we argue that malicious agents may exhibit collaborative behaviors, enabling more effective attacks through internal information exchange. In this paper, we propose an adaptive cooperative attack framework, where malicious agents autonomously coordinate and dynamically adjust their attack strategies through multi-round interactions. Furthermore, we introduce Sentence-Level Trustworthiness Analysis and Rectification (STAR), a defense framework that identifies and rectifies misleading information at the sentence level within agent communications. Our experiments show that cooperative attacks lead to a significantly larger degradation in task success rate than independent attacks, resulting in a relative drop of 5.34%. Meanwhile, STAR effectively mitigates both cooperative and independent threats and improves task success rate by an average of 36.76%. The code is available at https://github.com/smoooom/STAR.
May 27, 2026cs.AI

Examining Agents' Bias Amplification versus Suppression in Multi-Agent Systems

Multi-agent systems are increasingly deployed to support various tasks where agents interact to achieve individual and collective objectives. Although these systems can enhance task performance and decision-making, fairness preservation through bias reduction remains challenging. This study examines how agent-level biases shift and impact system-wide fairness. We use prompts to expose individual agents to group-favoring bias, then assess downstream impacts at the system level. To quantify the impact, we propose Favor Bias Strength (FBS), a zero-centered metric that decomposes bias alteration between favored-group uplift and disfavored-group suppression. Using multiple agent designs, benchmarks, and up-to-date large language models, we show that agents endowed with bias can substantially affect system-wide fairness. Interestingly, when agents are exposed to bias uniformly, the system-wide bias elevates, even exceeding the additive sum of the individual agents' biases. The empirical evidence underscores the criticality of fairness in multi-agent systems, which warrants further analyses and empirical tests.
May 27, 2026cs.AI

FundaPod: A Multi-Persona Agent Pod Architecture with Knowledge Graph Memory for AI-Assisted Fundamental Investment Research

Large language models (LLMs) are increasingly applied in finance, yet most existing work emphasizes trading signals or financial NLP tasks centered on prediction. Institutional fundamental research, by contrast, requires human analysts or AI agents to gather evidence, identify business drivers, compare competing viewpoints, and generate investment memos. Its broader goal is not merely to predict outcomes, but to produce investment plans that are transparent, reusable, and verifiable, while contributing to the cumulative development of investment knowledge. We present FundaPod, a multi-persona agent pod architecture for AI-assisted fundamental investment research. We argue that fundamental research is a human-centric decision-support task that is qualitatively distinct from trading-signal generation, and is therefore better served by an independence-preserving architecture. In FundaPod, AI agents with different personas, such as value investors or macro strategists, conduct research independently under a shared provenance contract. Their disagreements are then surfaced post hoc for adjudication by the human portfolio manager (PM) through a knowledge-graph memory system. This paper contributes five design principles for human-AI hybrid systems supporting fundamental research, grounded in design-science practice and theories of cognitive isolation and human-machine coordination. It also describes four architectural mechanisms: a persona distillation pipeline that turns public investor materials into deployable agents; a declarative skill registry that lets the planner derive typed task graphs; a grounded evidence model that links memo claims to verifiable sources; and a knowledge-graph "second brain" that connects tickers, memos, analysts, and themes. We demonstrate the architecture through a complete case study and a persona-based memo comparison.
May 27, 2026cs.AI

MolLingo: Molecule-Native Representations for LLM-Powered Scientific Agents

We present MolLingo, a multi-agent system that emulates the reasoning process of a chemist to automate molecular design. Existing LLM-based approaches either operate as standalone generative models without access to external tools or lack the multi-agent coordination and shared memory needed for iterative, evidence-driven reasoning across the molecular design pipeline. MolLingo addresses this by coordinating a Literature Agent, a Chemist Agent, and an Orchestrator through a shared memory module, with each agent equipped with domain-specific tools. To enable effective molecular reasoning, we introduce BRICS-based Fragment Enumeration (BFE), a synthesis-aware molecular fragmentation method that decomposes molecules into chemically meaningful building blocks represented as block-based SMILES paired with common chemical names. This representation bridges molecular structure and LLM semantic space, enabling block-level reasoning and editing that is difficult with raw SMILES alone. As a case study in early-stage therapeutic design, MolLingo further grounds the Chemist Agent's reasoning in binding site geometry and residue-level protein context derived from molecular docking to optimize molecules for stronger target binding. Across four benchmarks, MolLingo consistently outperforms frontier LLMs and specialized baselines, including a fourfold docking score improvement over GPT-5.4 despite using the same underlying model, consistent drug property optimization gains across multiple LLM backbones, and state-of-the-art results on TOMG-Bench, surpassing both frontier LLMs and the RL-based optimization method RePO. Our results suggest that LLMs are already capable molecular design assistants when guided through chemically meaningful representations and biologically grounded structural context. Code is available at: https://anonymous.4open.science/status/MolLingo-7450.
May 27, 2026cs.AI

TCP-MCP: Landscape-Guided Co-Evolution of Prompts and Communication Topologies for Multi-Agent Systems

Effective multi-agent systems cannot be designed by selecting prompts or communication graphs in isolation. Agent behavior depends on the information an agent receives, while the usefulness of a communication edge depends on how the receiving agent interprets and uses that information. We propose \textbf{TCP-MCP} (Topology-Coupled Prompting for Multi-Agent Collaborative Problem-Solving), a co-evolution framework that searches agent prompts and communication topologies as a unified genome. TCP-MCP uses an initialization-time landscape probe to calibrate early search behavior, and then relies on Pareto-front diagnostics to adapt exploration under three objectives: task performance, token cost, and structural complexity. Using the same DeepSeek-V3.2 backbone across all methods, TCP-MCP achieves 82.66%, 89.96%, and 96.61% accuracy on MMLU-Pro, MMLU, and GSM8K, respectively. Across the three benchmarks, it consistently outperforms automated graph-generation baselines and achieves competitive accuracy relative to debate-style systems, while using up to 5.69×\times fewer tokens than those systems at the reported operating points. These results show that jointly evolving prompts and communication structure provides a practical route to cost-aware and task-adaptive multi-agent system design in controlled evaluations.
May 26, 2026cs.AI

Got a Secret? LLM Agents Can't Keep It: Evaluating Privacy in Multi-Agent Systems

LLM safety evaluations predominantly test models in isolation, yet deployed AI agents increasingly operate within persistent social environments alongside other agents. We introduce a Moltbook-style simulation platform where thousands of LLM agents interact across communities over a simulated month, and use it to evaluate privacy as a downstream safety concern under varying degrees of social pressure. We find that shifting from single turn to multi turn social evaluation amplifies privacy violations (CIMemories 19.95% to Ours 45.30% across OpenAI models), that leakage is socially contagious, with agents 8 times more likely to disclose sensitive information after observing a peer do so, and that explicit privacy instructions reduce but do not eliminate this effect, leaving leakage rates above 37.8% even with safeguards. Our findings suggest that static chat based safety benchmarks systematically underestimate risks in agentic deployment, and that social context alone is sufficient to elicit sensitive disclosures that single turn evaluations would never surface.
May 26, 2026cs.AI

A Policy-Driven Runtime Layer for Agentic LLM Serving

Multi-agent LLM systems have become the dominant production workload, but the serving stack was not built for them. The agent framework above knows agent identities, role, schemas, and dispatch structure but never sees an engine-level event; the serving engine below sees every event but knows nothing about agents. A surprising number of cross-cutting policies depend on both: prefix caching, batch shaping, speculative execution, fairness, tool-result memoization, safety enforcement, and more. Each lives in the seam between the two layers and is currently solved by a one-off patch into one neighbor or the other. We argue this seam is best addressed by an architectural change rather than point fixes: insert a third tier, an agent runtime layer, between the framework and the engine, exposing four primitives (observe, score, predict, act) into which any agent-aware policy plugs, with agent identity as the shared coordinate. We map nine concrete policies onto the layer and validate the abstraction in depth on the one with the largest immediate serving-cost lever: KV caching across sessions, instantiated as CacheSage, which learns the per-workload agent transition matrix online and uses it for survival-based eviction and between-step prefetch. Preliminary results on five real multi-agent workloads show +13 to +37 pp cache hit-rate lift, 12% to 29% lower mean TTFT, and 6% to 14% higher throughput over an unmodified serving stack.
May 26, 2026cs.MA

Decoupled Intelligence: A Multi-Agent LLM Framework for Controllable Traffic Scenario Generation in SUMO

The integration of Large Language Models (LLMs) with microscopic traffic simulation offers a promising path toward autonomous urban planning and intelligent transportation analysis. However, existing monolithic agent architectures often struggle with the complexity of end-to-end simulation workflows, leading to reasoning failures, parameter inconsistency, and a lack of systematic state management. This paper proposes a novel multi-agent collaborative framework designed to automate the entire lifecycle of traffic simulation in SUMO (Simulation of Urban Mobility). Our approach decouples the simulation pipeline into specialized roles, including Planner, Builder, Demand, Runner, and Analyst, coordinated by a high-level reasoning engine. We introduce a state-persistent Orchestrator leveraging the Model Context Protocol (MCP) to ensure seamless data handover and environmental consistency across distributed agent actions. This architecture enables a robust closed-loop refinement process, where simulation outcomes are iteratively analyzed and optimized to satisfy user-defined Key Performance Indicators (KPIs). Experimental results through role ablation studies demonstrate that the proposed multi-agent framework significantly enhances task success rates and parameter accuracy compared to single-agent baselines. Furthermore, case studies on real-world network extraction and traffic optimization highlight the system's capability to bridge the gap between high-level natural language intent and low-level simulation execution.
May 26, 2026cs.AI

Discovery Agents for Real-Time Analytics: Toward Proactive Insight Systems

Modern analytics systems are fundamentally reactive, requiring users to define queries over increasingly complex and continuously evolving data. In real-time streaming environments, this paradigm breaks down, as the space of potential insights becomes too large to enumerate manually. We present a multi-agent architecture for autonomous insight discovery over real-time data streams. The system implements a continuous discovery loop in which agents generate hypotheses, compile them into executable analytics, validate generated artifacts, and produce visualizations and deployable applications. The architecture leverages Apache Kafka for event-driven coordination, Apache Flink for stream processing, and large language models to implement specialized agents. A key contribution is a contract-driven design based on typed intermediate artifacts, enabling modularity, observability, lineage, and safer execution of dynamically generated analytics. Through use cases in retail, finance, and public data, we show how this architecture supports a shift from query-driven analytics to proactive, discovery-driven systems.
May 26, 2026cs.CR

HARP: Measuring Harm Amplification in Multi-Agent LLM Systems

Multi-agent LLM systems decompose workflows across agents, tools, shared context, memory, and decision gates. This modularity improves interpretability, but creates a propagation risk: a bounded perturbation to one component can be reused by other agents and amplified into system-level harm. We introduce HARP (Harm Amplification through Role Perturbation), a trace-first methodology for studying local-to-global harm amplification in multi-agent LLM systems. HARP compares paired clean and perturbed executions and records specialist outputs, tool calls, memory reads/writes, guard events, oracle logs, latency, token cost, and decisions. We define local harm as deviation from targeted agents or corrupted channels, global harm as deviation over the full trace, and harm amplification as (H_global/H_local). This complements attack success rate with a measure of how strongly orchestration spreads harm beyond the attack point. We instantiate HARP in a finance-oriented seven-agent system with a deterministic decision gate and configurable attack harness for specialist compromise, collusion, shared-context corruption, and temporal or memory-persistent attacks. Across five defenses, prompt-only defenses preserve benign utility but leave high success and stealth; pre-tool and step-level guards reduce some failures with utility or latency costs; and IntegrityGuard, a trace-consistency defense, achieves the lowest attack success and global harm but introduces utility/cost trade-offs. Results show that single-specialist compromise produces the strongest amplification, shared-context corruption yields the highest attack success, and temporal persistence produces the largest malicious impact. HARP argues that secure multi-agent evaluation must measure not only bypass, but propagation.
May 26, 2026cs.AI

Traceable Knowledge Graph Reasoning Enables LLM-Assisted Decision Support for Industrial VOCs in the Steel Industry

Key knowledge for steel-industry volatile organic compounds (VOCs) governance is scattered across unstructured scientific literature, making it difficult to integrate process, pollutant, and control-technology evidence and increasing the risk of hallucination when general large language models (LLMs) answer low-frequency industrial questions. Here we developed Chat-ISV, a knowledge graph (KG) enhanced multi-agent Q&A system that parses a curated steel-industry VOCs literature corpus, constructs a Neo4j KG with 27180 nodes and 81779 semantic edges, and combines prompt-constrained extraction, chunk-centered topology optimization, multi-agent routing, source-backtracking retrieval, local literature retrieval, open-domain knowledge access, and interactive subgraph visualization. Benchmark tests and 400 expert blind evaluations showed that topology optimization reduced isolated nodes from 57% to 4.08% and that Chat-ISV achieved high factual reliability, with 96.93% precision, 72.63% recall, an F1-score of 0.830, and a mean score of 1.69/2.00. By converting fragmented environmental-engineering literature into traceable, queryable, and decision-support-oriented knowledge, Chat-ISV establishes a scalable environmental-informatics paradigm for reliable LLM deployment and intelligent pollution-control decision support in specialized industrial domains.
May 26, 2026cs.AI

Helicase: Uncertainty-Guided Supply Chain Knowledge Graph Construction with Autonomous Multi-Agent LLMs

LLM-based multi-agent systems have been widely adopted for knowledge retrieval and report generation, synthesizing known information through web search and textual reasoning. However, many critical information tasks in supply chains are not simple one-shot queries: they are structural inference problems requiring multi-hop reasoning across complex, fragmented web resources. Questions such as \textit{``Which Tesla components use lithium from Australian mines?''} have no answer in any single document; answers must be computationally synthesized through the autonomous construction and analysis of dynamic knowledge graphs assembled from fragmented, heterogeneous sources. Moreover, such discovery processes must be uncertainty-aware: decisions depend not only on answers but on calibrated confidence in their reliability, traceable to source quality and reasoning consistency. To address this capability gap, we propose \textit{Helicase}, an autonomous multi-agent LLM system for uncertainty-guided supply chain knowledge graph construction. \textit{Helicase} decomposes high-level supply-chain queries into executable investigation plans, coordinates specialized web-search, reasoning, and coding agents through iterative verification loops, and incrementally constructs query-specific supply chain knowledge graphs with per-fact uncertainty annotations. Its three-layer uncertainty framework tracks uncertainty at the action, trajectory, and memory layers, enabling both structural inference and calibrated confidence assessment. To evaluate autonomous reasoning across the full complexity spectrum, we introduce SCQA (Supply Chain Query Assessment), a benchmark of 80 supply chain queries organized into four quadrants spanning single-hop to multi-hop inference under both high and low data visibility.
May 26, 2026cs.MA

AgensFlow: A Coordination-Policy Substrate for Multi-Agent Systems

Multi-agent systems built on large language models (LLMs) require many coordination choices that are difficult to fix a priori: which skill protocol to invoke, which agent role should perform a subtask, which model to bind to each role, how roles should interact, when to use retrieval or verification, and when to omit a step entirely. These choices interact with task regime and operational constraints, so static pipelines and one-off model comparisons provide only a limited view of the design space. This paper introduces AgensFlow, an open-source framework that treats multi-agent coordination as an online policy-learning problem under partial observability. The framework makes coordination decisions observable and learnable from repeated trajectories, rather than treating skill, role, model, topology, and evaluation choices as fixed pipeline design. AgensFlow is evaluated on two corpora: distributed-systems incident tasks and security-advisory tasks. The evaluation shows three main results: learned routing reaches a higher-quality operating point than a fixed pipeline baseline on coordination-heavy classes; skip:X isolates topology compression as a meaningful part of the substrate; and warm-started policy graphs can reduce exploration cost while preserving plateau quality. Overall, the results support that learned, auditable routing can improve coordination-heavy multi-agent workflows over static wiring.