Gradient Surgery

Background: Large language models (LLMs) have achieved physician-comparable performance on multiple-choice medical knowledge examinations, but their capabilities in clinical history taking, urgency assessment, and safety remain insufficiently evaluated. We proposed Japanese Stroke LLM Evaluation, a multi-turn conversational benchmark for stroke care in Japanese, and evaluated LLM performance and safety under practice-oriented conditions. Methods: We created 10 stroke and related-condition cases and evaluated LLMs in multi-turn Japanese conversations. The LLM acted as physician, while a board-certified neurosurgeon acted as simulated patient and evaluator. Each case comprised history-taking and action phases scored using pre-specified criteria. Errors that could directly threaten life were defined as critical mistakes. The safety threshold was at least 80% overall with zero critical mistakes. Eighteen models were evaluated in October 2025 and June 2026. Results: Claude Fable 5 achieved the highest score (87.4%) with zero critical mistakes, followed by Claude Opus 4.7 (80.3%) and GLM-5.2 (75.6%). Two leaders met the safety threshold. Eleven models made 17 critical mistakes, including failure to confirm laboratory results or blood glucose before t-PA, surgery before airway stabilization, omission of cervical vascular evaluation, and t-PA outside its indication. History-taking question count correlated with history-taking score (r = 0.648, p = 0.007). Conclusions: Japanese Stroke LLM Evaluation provides a benchmark for LLM performance under practice-oriented conditions, including a cap on history-taking questions. Cases and evaluations were created by neurosurgical specialists rather than using an LLM-as-judge approach. Performance improved across cloud-based and on-premise models in 2026, with some exceeding the safety threshold. Further evaluation using real-world cases is required.

Purpose: Paired pre- and post-operative photographs are the standard unit of evidence for plastic surgical outcomes, yet no objective metric verifies whether two images of the same patient were captured under conditions consistent for comparison. Approach: We developed a perceptually motivated pipeline that analyzes pre/post pairs across thirteen calibrated sub-metrics, partitioned by unsupervised correlation-structure analysis into five data-driven clusters (photometric, texture / sharpness, pose, illumination direction, and pitch), averaged within each cluster and combined across clusters by a weighted sum into a single consistency score. Each sub-metric is calibrated so that its median difference across published within-patient pairs scores 0.5, which is a reference point and carries no pass/fail meaning. The pipeline was calibrated on 134 matched within-patient published pre/post pairs and evaluated against identical-image pairs, synthetic-perturbation pairs, and 134 mismatched cross-publication pairs. Results: The master consistency score S separated matched from mismatched pairs (sensitivity index d' = 2.15, 95% confidence interval (CI) [1.83, 2.55]; area under the receiver operating characteristic curve AUC = 0.928, 95% CI [0.896, 0.959]), closely matching Gaussian-equal-variance predictions. The three head-pose angles did not fall in one cluster: yaw and roll grouped together while pitch separated. Identical pairs scored at ceiling (S = 0.99) and the master score fell monotonically with perturbation magnitude on all five perturbation axes. Conclusions: The score quantifies photographic comparability, not aesthetic or surgical quality, and provides a freely available web tool for auditing the photographic comparability of pre/post pairs, pending validation against expert judgment.

Scientific machine learning methods such as physics-informed neural networks (PINNs) increasingly rely on domain decomposition for better scalability while solving partial differential equations (PDEs) over complex geometries, yet the resulting composite loss comprising residual, boundary, and interface terms is highly susceptible to conflicting gradients that degrade training. This work bridges domain decomposition with projection-based gradient surgery to systematically mitigate such conflicts in 2D and 3D settings. We evaluate two existing projection-based algorithms, PCGrad and ConFIG, and identify their performance degradation in specific scenarios such as 3D domains with multiple overlapping interfaces. To address this limitation, we propose Norm-PCGrad, a normalized variant that achieves state-of-the-art accuracy across a range of 2D and 3D domain decomposition problems. Across the benchmarks considered, Norm-PCGrad consistently achieves the lowest relative $L_2$ error compared to training without gradient surgery as well as to existing algorithms such as PCGrad and ConFIG, while incurring negligible additional computational overhead. To improve computational efficiency of domain decomposition frameworks such as Extended PINN (XPINN), we propose replacing vanilla PINNs in selected subdomains with separable architectures such as Separable PINN (SPINN), reducing the computational cost from quadratic (or cubic) to linear. We additionally demonstrate that gradient surgery extends to physics-informed Kolmogorov-Arnold Networks (PIKANs), yielding substantial accuracy improvements for 3D domain decomposition and confirming the generality of the proposed approach across network architectures.

In data-driven training, multivariate time-series forecasting is usually optimized with a scalar loss averaged over samples, variables, and horizons. This averaging is convenient, but the optimizer sees only the aggregated gradient, which does not reveal whether the variable-wise contributions align or oppose one another. To quantify how often this disagreement arises, we measure the variable-wise gradients directly and find that 30.6% of their pairwise cosine similarities are negative on average across seven datasets. However, conflict and harm are not the same thing. Under shared training 35 of the 64 variables do worse than a full-input single-target oracle, and the harmed fraction is not reliably predicted by how often gradients conflict. We propose Per-Variable Surgery (PV-Surgery), an optimizer-side training strategy for backbones with cache-compatible layers. One backward pass builds variable-wise gradient proxies from output-side signals and keeps the pointwise forecasting loss. Reliability-aware selection targets layers whose proxy sums closely approximate their shared-gradient slices. Conditional pooling forms anchor and conflict pools without dropping variables. Common-direction surgery aligns variable or pooled gradients with their normalized mean and restores input norms to avoid reweighting. In experiments across five backbones, seven datasets, and four horizons, PV-Surgery lowers MSE by 3.61% and MAE by 2.93% on average. For multivariate forecasting, this indicates that the variable-wise structure hidden by mean-loss training is a usable optimization signal.

Robotic ophthalmic surgery offers high precision but introduces a "sensory gap" by decoupling the surgeon from their instrument, resulting in a loss of tactile feedback. This paper presents a novel haptic feedback system for subretinal injection tasks leveraging Scene Graphs (SG). The system bridges the sensory gap by analyzing a physically simulated intraoperative Optical Coherence Tomography (iOCT) feed to construct a real-time surgical SG. The SG serves as a semantic abstraction layer for the surgical scene, which is then utilized by a deterministic, rule-based engine to generate state-dependent haptic feedback on a robotic input device. The system was evaluated in a user study (N=16) using an anthropomorphic head phantom and a custom-built surgical robot. Results demonstrate that the SG-driven haptic feedback improved surgical precision, reducing needle alignment error by 14% (p = 0.044) and improving System Usability Scale (SUS) scores by 8% (p = 0.015), while maintaining comparable task completion times. A needle trajectory analysis revealed the emergence of a safer "Align-then-Approach" strategy, in which our haptic negative reinforcement prompted users to fine-tune the tool's trajectory before approaching the retinal target. This work suggests that SGs can effectively serve as the direct computational foundation for real-time, safety-enhancing context-aware haptic feedback in robotic microsurgery.

Objective assessment of surgical technical skill is important for surgical training and structured feedback, but current workflows remain dependent on labor-intensive expert review. Existing automated approaches primarily focus on visual inputs and provide limited support for jointly studying operative performance, structured skill scores, and evaluator feedback. We introduce SurgSkill-Bench, an initial video-score-text benchmark-style dataset containing 214 surgical training simulation videos, six-dimensional OSATS scores, and expert free-text comments. We define two evaluation settings: video-only OSATS prediction for automated assessment and post hoc expert-comment-assisted prediction, where evaluator comments are available as auxiliary information. We provide controlled baseline experiments using representative frozen visual backbones, content-adaptive key-frame sampling, and a simple video-text co-attention fusion module. Under internal video-level validation, content-adaptive sampling improves video-only performance in this dataset, while evaluator comments provide additional score-related signal in the assisted setting. The best mean AUROC reaches 0.88 under dataset-specific median dichotomization. We further discuss evaluation constraints related to dataset scale, metadata completeness, and the interpretation of comment-assisted prediction. Code will be released publicly at a later date.

High-resolution images of unprocessed surgical breast tissue can be obtained using microscopy with ultraviolet surface excitation (MUSE). This technique is considered a promising method for checking surgical margins during breast cancer surgery. In this study, MUSE images at 4x and 10x magnifications were compared using patch-level classification methods. Texture analysis (TA) based on local binary patterns (LBP) and deep learning (DL) with a base Vision Transformer (ViT) model were used. Both methods achieved similar performance at both magnifications. Using DL method, both 4x and 10x magnifications achieved 96.30% sensitivity, 100% specificity and 98.18% accuracy. Using TA method, 4x achieved better specificity (100% vs 93.33%) and 10x yielded higher sensitivity (100% vs 93.33%), but both had the same accuracy (96.67%). No clear improvement in performance was observed with 10x magnification. These results show that 4x imaging achieves the same diagnostic accuracy as 10x imaging. At the same time, 4x offers a larger field of view and faster image capture. Therefore, lower magnification can be effectively used in MUSE systems for accurate and efficient intraoperative margin assessment.

The convergence of the Metaverse and Large Language Model (LLM)-based AI agent is catalyzing a shift toward autonomous, immersive, and personalized pedagogical frameworks in medical education. This paper presents a novel agentic AI-driven immersive simulation specifically designed for High Dose Rate (HDR) vaginal cylinder (VC) brachytherapy in cancer care. By integrating Virtual Reality (VR) and mobile computing, the system establishes a high-fidelity, risk-free environment that allows trainees to master complex procedural skills without the facility or safety constraints posed by physical anatomy or live radioactive sources. A core contribution of this work is the seamless integration of a knowledge-aware assistant leveraging Retrieval-Augmented Generation (RAG) to ground agent interactions in authoritative clinical guidelines. This architecture also enables an interactive agent to provide natural language interfaces and hands-free, real-time guidance during intricate medical maneuvers. We validate the proposed system through a prototype deployment comprising a Meta Quest 3 interface linked to a local GPU-accelerated AI backend, demonstrating a feasible architecture for HDR brachytherapy simulation. Experimental results indicate that the system maintains suitable end-to-end latency and high context precision, answer completeness, and relevance in the RAG-enhanced pedagogical support.

Reliable surgical planning requires models that move beyond recognizing the current surgical step or imitating expert demonstrations, and instead anticipate how instrument motion reshapes subsequent operative states. Most surgical video understanding methods focus on recognizing phases, actions, or workflow states, while providing limited support for explicitly modeling instrument motion. Conversely, existing tool motion prediction methods can forecast instrument trajectories, but they generally do not capture the coupled evolution of future surgical video states. World models offer a natural framework for jointly modeling visual state transitions and instrument motion dynamics. However, existing surgical world model studies remain largely centered on visual generation quality, relying on generation-oriented metrics such as FVD and CD-FVD. These metrics are poorly aligned with instrument motion planning, as they do not directly measure whether predicted trajectories are geometrically accurate, temporally coherent, or actionable for downstream planning. This limitation is partly structural, since the field lacks public datasets and standardized evaluation protocols that provide the benchmarking infrastructure needed to assess motion-centric capabilities in surgical world models. In this paper, we introduce SurgWMBench, a vision-based benchmark for short-horizon surgical motion planning and dynamics prediction. Given intraoperative image sequences and historical instrument trajectory, SurgWMBench evaluates both near-future instrument motion prediction and stability under continuous rollout or input perturbations.

Controllable surgical world models can provide a generative foundation for surgical artificial intelligence and simulation by synthesizing realistic instrument--tissue interactions. However, existing methods lack a unified multimodal control paradigm, while direct fusion of heterogeneous visual conditions often causes anatomical distortion, instrument appearance drift, and temporally inconsistent interactions. In this work, we propose {Surg-UniWorld}, a unified surgical world model with multimodal control experts. Surg-UniWorld first constructs a {Hierarchical Surgical Anchor} from first-frame appearance and hierarchical semantic masks to preserve persistent scene identity, anatomical organization, and interaction boundaries. {Anchor-Relative Modality Experts} then interpret edge, depth, and optical-flow evidence relative to the shared anchor, capturing complementary boundary, geometric, and motion information. A {Multimodal Control Expert} further performs contribution-preserving stage-wise composition of the activated modality increments and generates control hints for the Wan2.2 video diffusion backbone. To support multimodal surgical world modeling, we further construct Cholec80-SurgWAM, a benchmark for controllable surgical video generation. Extensive experiments demonstrate that Surg-UniWorld consistently outperforms existing controllable video generation methods and surgical world-model baselines in generation quality, temporal consistency, and multimodal controllability.

Mandibular reconstruction restores facial continuity and oral function after segmental resection. Patient-specific cutting guides transfer a computed tomography (CT)-based plan to the operating room with three-dimensional information, but printed guides add cost and lead time, cannot adapt after fabrication, and may interrupt surgery if sterility is lost. We investigate a markerless augmented reality (AR) alternative that registers a virtual cutting guide to the exposed mandible from surface geometry. The method extends surface-based registration for the transoral setting, where teeth form the most distinctive visible surface. After camera calibration, a HoloLens 2 time-of-flight camera captures a partial intraoperative point cloud. The user supplies a rough head-based alignment only to crop the region of interest. A teeth-weighted global stage computes correspondences and solves a truncated least-squares rigid alignment. An asymmetric point-to-plane iterative closest point (ICP) stage refines the complete CT mandible against the partial depth cloud target. The guide-to-mandible transform places the guide in the HoloLens world frame, while pose updates and interpolation follow target motion. We define a blinded phantom protocol with 30 target registration error (TRE) points under full, intermediate, and teeth-only exposure, plus a motion-to-display latency test. Our median TRE is 4.05, 6.10, and 7.10 mm respectively, and median latency is 0.805 s. These values support the feasibility of using AR to replace physical prints. The workflow removes mounted fiducials and manual landmark selection and provides a testable path toward transoral cutting guidance.

Surgical procedures unfold as structured and recurring clinical events, whose real-time understanding via intraoperative surgical videos is critical for intraoperative decision-making and support. However, existing video understanding methods force a trade-off: autoregressive video-language models support comprehensive reasoning but are not practical for time-sensitive clinical applications, whereas contrastive models offer low latency but struggle with complex scene understanding. Recently, generative retrieval has been explored for general-domain video understanding, but transferring it to surgery is not trivial because near-identical visual appearances may indicate semantically distinct events, and the terminology involved is highly surgery-specific. To this end, we propose SurgNarrator, a new generative retrieval framework tailored for surgical video understanding. We construct a well-curated surgery-centric vocabulary from surgical captions to define a clinically meaningful retrieval space. We then adapt the pre-trained Qwen3-VL-Embedding-8B to learn discriminative clinical representations with a temporally-aware contrastive objective. During inference, a hierarchical, procedure-aware retrieval strategy narrows the search space to the relevant procedure type, delivering fast and effective responses. Our method is comprehensively evaluated on twelve benchmarks in a zero-shot setting and achieves consistent performance gains over state-of-the-art baselines, while reducing output-stage latency by more than two orders of magnitude compared with the generative baseline.

Understanding complex surgical scenes requires recognizing multiple interdependent entities, such as instruments, actions, and targets, while maintaining their relational consistency across time. Existing surgical triplet recognition methods struggle to jointly model intra-frame label dependencies and inter-frame temporal semantics in a unified manner. To address these limitations, we propose a unified framework that integrates spatial, relational, and temporal cues for robust surgical triplet recognition. Specifically, class-specific spatial priors are first extracted through a multi-scale encoder. These priors are then refined by a Label Correlation Modeling module with multi-scale class activation map-guided relational extraction (MS-CAMRE), enabling the model to capture both static co-occurrence patterns and dynamic contextual dependencies among triplet components. Furthermore, a Bidirectional Temporal-Relational Fusion Attention (BTRFA) module harmonizes temporal and relational representations to achieve coherent temporal reasoning. We also introduce a new evaluation metric, the Triplet Consistency Error Rate (TCER), which quantitatively measures the model's ability to preserve causal and semantic consistency across triplets. Extensive experiments on the CholecT45 and ProstaTD datasets show that our method achieves state-of-the-art performance, improving AP_IVT by 5.1 percent and 7.8 percent, respectively. Moreover, according to TCER, our approach achieves relative reductions of more than 36 percent and 25 percent on the two datasets, respectively, demonstrating the effectiveness of our framework in temporal-relational co-reasoning.

In robot-assisted surgery, Forbidden Region Active Constraints (FRAC) represent a control strategy that helps maintain task safety by generating anisotropic haptic guidance to surgeons. However, several challenges need to be overcome before FRAC can benefit teleoperative surgery in a clinical setting. These challenges include the ability to allow for dynamic tissue deformation, maintain energetic passivity, and speed of implementation, among others. In this study, we propose the pipeline design for an energy dissipative FRAC strategy, which accommodates the dynamic tissue deformation caused by respiratory movements, by utilizing a depth sensing camera. The proposed FRAC strategy adopts a fine mesh representation, with a total number of 122,806 polygons in the case study presented, while running at 43.48Hz. We designed in vitro trajectory tracking experiments conducted by a "virtual" surgeon to aid quantitative assessment of the method, including its effectiveness in maintaining task safety, which was confirmed by successfully maintaining a pre-defined safety distance across all trials. We also conducted comparative studies to investigate the robustness and time-efficiency of our method against other FRAC methods that rely on simple geometry AC representations. We demonstrate that our method provides a more robust and effective guidance overall, while maintaining comparable, if not lower, time costs.

Computational attention models could help surgeons manage the visual demands of laparoscopy, but they require dense spatial labels that are difficult to obtain because surgical intent is highly specialized and tacit. Here, we introduce DiffeoAfford, an action-grounded tissue affordance framework that retrospectively derives visual attention supervision from completed surgical procedures. By combining diffeomorphism-constrained tissue tracking with instrument trajectory analysis, DiffeoAfford generates affordance hotspot labels without manual per-frame annotation. A real-time prediction model trained on these labels anticipates relevant surgical regions and enables AffordView, an assistive auto-framing system for laparoscopic visualization. The proposed framework aligns with expert annotations and intraoperative surgeon gaze, and reduces surgeon cognitive workload during real-world evaluations using subjective, physiological, and behavioral measures.

Effective multi-organ segmentation in surgical data requires learning the intricate anatomical features and alleviating the challenge of class imbalance, which results from relatively lower proportions of small and limitedly exposed structures. Recent works on laparoscopic multi-organ segmentation focus on learning structure-specific features through class-specific decoder architectures and report favorable results. This work extends the decoder-focused architectures to investigate knowledge sharing in the cross-surgical domain. We utilize two datasets representing different surgical domains, rectal and cholecystectomy surgeries, to explore how surgical conceptual knowledge transfers under partially common anatomical representations. Additionally, we compare the feature adaptation for the encoder and decoder at different training stages to analyse the knowledge adaptation and retention in the network. Our results corroborate previous findings on decoder-specific architectures and demonstrate that the organ-specific decoder model (CEMD), fully fine-tuned after cross-domain pre-training, achieves the highest segmentation performance (62.4% dice) while converging substantially faster than training from scratch. However, we also find that class imbalance in surgical data remains a persistent challenge that transfer learning does not fully resolve for underrepresented anatomical structures.

Effective flood monitoring is critical for minimizing the impacts of flood disasters on populations and infrastructure. Yet reliable remote sensing across extensive and environmentally diverse regions remains challenging, as most segmentation algorithms lack the generalisation capacity required for large-scale application, while annotated flood data are scarce and unevenly distributed. This study presents an end-to-end multimodal framework for Russian Federation territories sustainable flood monitoring and damage assessment based on synthetic aperture radar data, multispectral imagery, and digital elevation models with their derivatives, forming a 21-channel input. Using a self-collected multimodal dataset covering seven Russian regions, two strategies for water surface detection under limited data conditions were compared: a supervised U-Net++ model and the self-supervised AnySat architecture pre-trained and fine-tuned for the segmentation task. Under the data conditions of this study, supervised learning proved more effective, while the AnySat-based approach offered greater stability and retains advantages for settings where larger unlabelled data or missing modalities at inference are expected. The best flood area predictions were used to estimate flood impact in urban areas in terms of the area affected, material damage, casualties, and ecological and agricultural impact. The estimations were conducted following the official methodology of the Russian Ministry of Emergency Situations. Applied to the 2019 Tulun flood, the obtained results closely matched official assessments, except for material damage, due to the open-source databases usage. The results demonstrate the potential of deep learning and multimodal satellite data integration for scalable, reliable flood monitoring across diverse environmental and data-limited conditions.

We present MiSS, a black-box, query-based framework for explaining 3D point cloud classifiers through perturbation-relative sufficiency reasoning. MiSS treats a superpoint partition as an interpretable abstraction layer and asks whether the original prediction can be certified from a minimal coalition of geometric regions under a specified perturbation distribution. Unlike abductive explainers that require Boolean feature spaces or white-box logical encodings of the predictor, MiSS separates candidate proposal from verification: a weighted MaxSAT procedure proposes coalitions using a heuristic adaptive cardinality floor, certified exact-size fallback, a safely tightened upper bound, blocking clauses, and a surrogate acquisition heuristic learned from previous oracle evaluations, while a blackbox statistical oracle decides sufficiency from prediction queries. The system returns a statistically verified sufficient coalition as a binary attribution, with minimum cardinality guaranteed when certified search completes. Experiments on ModelNet40 and ShapeNet with PointNet and PointMLP classifiers show higher precision and coverage than rule-based baselines in most settings, with lower explanation time than exhaustive search.

Intraoperative 2D/3D registration aligns preoperative CT volumes with intraoperative X-ray or fluoroscopic images and is essential for image-guided interventions. Recent learning-based and differentiable registration methods have shown promising accuracy, especially in patient-specific settings where abundant digitally reconstructed radiographs (DRRs) can be synthesized from the target CT. However, training a separate patient-specific model from scratch for every new patient is computationally inefficient and limits practical deployment. In this work, we propose an efficient patient-specific 2D/3D registration framework based on patient-agnostic synthetic pretraining and spherical similarity learning. The model is first pretrained on synthetic DRRs generated from multiple CT volumes to learn transferable pose-sensitive representations, and is then adapted to a new patient using only a limited number of synthetic projections from the target CT. To improve synthetic-to-real robustness without requiring anatomical labels, we introduce a segmentation-free domain randomization strategy that perturbs image intensity, projection physics, field-of-view, occlusion, and fluoroscopic artifacts. The adapted model provides an initial pose estimate, which is further refined using spherical similarity learning and differentiable Levenberg-Marquardt optimization. Experiments on multiple anatomical datasets evaluate whether patient-agnostic synthetic pretraining can improve the efficiency of patient-specific registration, with particular focus on the trade-off between adaptation cost and registration accuracy. The results demonstrate that patient-agnostic synthetic pretraining can significantly reduce patient-specific training requirements while preserving accurate intraoperative 2D/3D registration.

Objective: We evaluated whether metric 3D geometry of neurosurgical operative exposure can be recovered from standard monocular operating-microscope images combined with microscope pose data. Methods: In a phantom-based laboratory study, two aneurysm training phantoms were imaged with a ZEISS Pentero 800 microscope integrated with Brainlab Cranial Navigation. Microscope images from the standard composite video output were stored with synchronous microscope poses. After intrinsic and extrinsic calibration, depth was estimated with the pretrained Depth Anything 3 model without task-specific fine-tuning. Fused point clouds were converted to meshes using Poisson surface reconstruction. Reconstructions were compared with reference surfaces from structured-light scanning and fine-slice CT. Results: For phantom A, representing a deeper surgical corridor, reconstruction accuracy ranged from 1.95 $\pm$ 1.70 mm to 2.33 $\pm$ 2.15 mm. For phantom B, representing a directly exposed surface, accuracy ranged from 1.02 $\pm$ 0.93 mm to 1.52 $\pm$ 1.21 mm. Larger image sets mainly improved completeness, while accuracy remained within a narrower range. Corridor analysis showed preservation of overall geometry with local deviations in incompletely reconstructed regions. Conclusions: Standard monocular microscope images combined with navigation-derived pose data can reconstruct millimeter-range 3D surfaces using a foundation-model-based pipeline. These results show technical feasibility in a controlled phantom setting and support further development toward objective quantification of operative exposure, image fusion, and characterization of working spaces for future surgical instrumentation.

Understanding instrument-tissue interactions is essential for context-aware surgical AI and autonomous robotic surgery. Pretrained vision-language models (VLMs) and vision encoders offer an alternative to conventional interaction classifiers by transferring broad visual and semantic knowledge. However, adapting them to fine-grained surgical interactions remains challenging: (1) freezing the vision encoder depends entirely on pretrained representations that may retain noise and provide weak spatial localization, while (2) full fine-tuning can improve global semantic alignment without ensuring that the encoder learns meaningful features in the correct action region. We address these limitations by introducing LAViFiT, an end-to-end latent-action-guided framework for vision-language fine-tuning. An inverse dynamics model captures the visual changes induced by each action, while a forward world model drives the encoder to represent action-relevant regions. A patch-level SIG Regularizer further prevents local feature collapse without additional supervision, such as bounding boxes or pseudo-labels. Experiments across multiple encoders and datasets improve recognition and image-text alignment, while representation analyses show stronger grounding over the complete instrument-tissue interaction region and more spatially coherent features.

Positive margins in head and neck oncologic surgery require mapping specimen-side pathology findings to the patient resection bed. This is challenging because pathologists identify the positive margin on slices of the resected, deformed specimen, while surgeons must relocate the corresponding site on the resection bed using only verbal descriptions and no visual guidance. We present a marker-free augmented reality (AR) workflow for mapping a margin label from a three-dimensional specimen scan to the resection bed. The method combines contour-constrained deformation, residual alignment to a depth scan, surface-based fusion to a head-mounted display, and target projection onto the reconstructed bed. Bead-suture correspondences estimate specimen deformation, whereas patient-to-display fusion does not require external fiducial markers. Following formative experiments, five residents and surgeons performed cadaveric cheek and scalp re-resection tasks under verbal guidance, verbal guidance with specimen examination, and AR guidance. Deformation target errors were $7.63 \pm 3.74$ mm for the cheek and $3.72 \pm 1.02$ mm for the scalp; residual specimen-to-bed distances were $2.43 \pm 2.15$ mm and $2.19 \pm 1.06$ mm, respectively. Fusion error did not differ significantly between marker-free and marker-based methods on either cadaver; overall marker-free fusion error was $2.15 \pm 0.87$ mm. End-to-end margin localization error decreased from $21.40 \pm 3.84$ mm with verbal guidance and $16.09 \pm 4.30$ mm with specimen examination to $6.19 \pm 1.79$ mm with AR guidance ($p < 0.001$). Online fusion required $5.23 \pm 0.34$ s. These results demonstrate effective marker-free AR guidance for positive-margin localization and support more precise tumor resection.

Point tracking in surgery is crucial to enable applications in downstream tasks such as segmentation, 3D reconstruction, virtual tissue landmarking, autonomous probe-based scanning, and subtask autonomy. This paper introduces the 2025 iteration of a point tracking challenge to address this, wherein participants submit their algorithms for quantification. Their algorithms are evaluated using a dataset named surgical tattoos in infrared (STIR), with the challenge named the STIR Challenge 2025 (STIRC2025). The STIR Challenge 2025 comprises two quantitative components: accuracy and efficiency. The accuracy component tests the accuracy of algorithms on in vivo and ex vivo sequences. The efficiency component tests algorithm inference latency. The challenge was conducted as a part of MICCAI EndoVis 2025, and seven teams participated in this challenge. In this paper we summarize the challenge results and participant methods. The challenge dataset is available at: https://zenodo.org/records/20191078, and the code for baseline models and metrics calculation is available here: https://github.com/athaddius/STIRMetrics

Recent advances in actuation, control and learning have rapidly pushed humanoid robots from a distant vision towards near-term real-world deployment. Healthcare is a particularly pressing domain, in which staffing shortages and increasing care demand are widening the gap between clinical workload and available skilled labour. Although current automation has largely focused on digital and logistical tasks, much hospital work remains embodied, requiring mobility, manipulation and safe interaction in human-designed environments. Humanoid form factors offer unique potential, particularly for assisting with surgical tasks. Traditionally, robotic systems for surgery are purpose-built platforms such as Intuitive Surgical's da Vinci Surgical System, and it remains unclear how close current humanoid systems are to meeting the precision, control and safety requirements of minimally invasive surgery. Here we present a systematic evaluation of contemporary humanoid technology for laparoscopic surgical tasks. We develop a humanoid-based laparoscopic teleoperation framework using general-purpose instruments and assess its abilities through benchtop characterization, dry-laboratory user studies spanning diverse surgical experience levels and in vivo porcine studies. Across these evaluations, we quantify technical feasibility, task performance and clinical readiness relative to established surgical platforms. Together, our study provides an evidence-based assessment of current humanoid abilities and limitations for surgical applications, highlighting both their promise and key technical challenges that must be addressed before clinical deployment.

Surgical automation is being increasingly studied, yet bridging visual scene understanding with autonomous action planning remains a fundamental challenge. While much research effort has been made on scene perception (e.g., tool recognition and scene segmentation), understanding and predicting actionable possibilities for surgical automation is still underexplored. In this paper, we introduce surgical affordance prediction, which identifies actionable regions for fundamental surgical actions from visual data. Specifically, a novel adaptive feature fusion framework is proposed that leverages the complementary strengths of a self-supervised vision transformer encoder for its superior semantic understanding and a large-scale generative model encoder for its spatially-aware capability. Furthermore, we introduce a hierarchical prompt learning mechanism to adapt to varying procedural contexts. Finally, a scene-guided attention decoder is proposed to focus on critical surgical areas while suppressing background distractions. To validate the effectiveness, we established a new dataset, derived from publicly available surgical datasets with affordance annotations for three basic surgical actions: aspiration, clipping, and retraction. Extensive experiments demonstrate that our approach achieves state-of-the-art performance. Moreover, we validate our framework's applicability for downstream automation on a realistic lung and prostate phantom, and results show that the predicted affordance maps successfully enable autonomous surgical actions.

Vision-Language-Action (VLA) models represent a promising direction for embodied intelligence in surgical robotics. Despite the prevalence of VLA benchmarks for general robotics, standardized evaluation platforms specifically designed for surgical contexts remain absent. To address this limitation, we present SurgVLA-Bench, the first comprehensive benchmark for evaluating VLA models in laparoscopic surgical robotics. Leveraging the SurRoL simulation platform, we construct a hierarchical task taxonomy ranging from atomic actions to complete surgical procedures, complemented by a multi-dimensional evaluation framework assessing action accuracy and semantic consistency. We then systematically evaluate two representative paradigms, including autoregressive models such as OpenVLA, and flow matching models such as $π_{0}$, $π_{0.5}$, and SmolVLA. Our experiments show that autoregressive models tend to excel in semantic understanding, while flow matching models often achieve higher task precision but may face generalization trade-offs. However, even the best-performing models remain far from satisfactory, as the constrained endoscopic field of view, restricted viewing angles, and frequent occlusions persist as fundamental physical bottlenecks. The code and data are available at https://github.com/VCL-HNU/SurgVLA

Transcatheter Aortic Valve Replacement (TAVR) planning requires meticulous multimodal reasoning. However, adapting Multimodal Large Language Models (MLLMs) to this high-stakes domain is severely impeded by diagnostic hallucinations, where generated text lacks anatomical grounding. To address this, TAVR-VLM is introduced: a novel framework featuring Risk-Conditioned Causal Grounding Attention (R-CGA) that instantiates a model-internal ``Risk $\rightarrow$ Region $\rightarrow$ Word'' structural grounding pathway. R-CGA compresses multimodal inputs into a causal risk bottleneck, purifying dense visual features into a global risk mask. During autoregressive generation, a support-projected causal consistency objective constrains token-level grounding within the risk-defined support mask. Evaluated on $\text{M}^3\text{TAVR}$, a comprehensive 1,482-patient cohort, TAVR-VLM establishes a new state-of-the-art. It achieves an AUROC of 0.896, boosts CIDEr to 0.936, and drastically reduces the hallucination rate to 8.1%, thereby improving interpretability for evidence-based surgical AI.

Effective multi-task learning for surgical scene understanding is fundamentally hindered by annotation granularity mismatch; temporal workflow tasks such as phase recognition, step recognition and anticipation benefit from dense frame-level supervision, whereas pixel-level spatial tasks including instrument segmentation and action recognition are only sparsely annotated on selected keyframes due to prohibitive labeling costs. This supervision imbalance undermines shared representation learning and limits joint optimization across heterogeneous surgical tasks. To address this, we propose Flow-guided Annotation for Robust Operating Scenes (FAROS), a flow-guided label interpolation framework, that combines zero-shot segmentation-based mask propagation with optical flow estimation to overcome the limitations of appearance-based propagation under challenging surgical conditions such as occlusion, smoke, and motion blur, generating temporally consistent dense pseudo labels from sparse keyframe annotations. The densified instrument masks and action labels are integrated into a unified Transformer-based multi-task framework that jointly learns surgical phase recognition, step recognition, anticipation, instrument segmentation, and action recognition, enabling balanced optimization between dense temporal supervision and sparse spatial supervision. The label interpolation quality of FAROS is first validated on the DAVIS 2017 benchmark under a sparse ground-truth protocol, confirming robust propagation beyond the surgical domain. Extensive experiments on GraSP, MISAW, and AutoLaparo benchmarks further demonstrate that FAROS significantly improves cross-task representation learning and enhances holistic surgical scene understanding performance across spatio-temporal tasks.

We introduce SurgAtlas, the largest surgical video-language dataset to date, comprising 15,291 videos (2,391 hours) spanning 18 surgical specialties and over 5,000 procedure types, sourced entirely from publicly available YouTube content. SurgAtlas is also the first surgical video-language dataset to include open surgery at scale, with 6,182 open procedure videos alongside over 9,000 minimally invasive recordings, and the first to establish standardized benchmarks for open-surgery video understanding. We additionally provide an expert-validated subset with verified visual question-answer pairs across diverse open and minimally invasive procedures, serving as a clinically grounded benchmark for surgical reasoning. Compared with existing surgical video-language datasets, SurgAtlas provides one of the most diverse annotation schemas, combining segment-level captions, step- and phase-level descriptions, video-level surgical descriptions, and reasoning-oriented question-answer pairs organized within a hierarchical taxonomy. These annotations are constructed through an automated multi-tier pipeline with LLM-based enrichment and a staged VQA generation framework with explicit groundedness verification. The scale and diversity of SurgAtlas enable training surgical foundation models with broad procedural coverage: we finetune Qwen3-VL-8B through a two-stage captioning-then-instruction pipeline and achieve competitive or state-of-the-art results on multiple established surgical benchmarks, including phase recognition, triplet detection, and reasoning question answering. More broadly, SurgAtlas provides a large native public video corpus that can support future large-scale pretraining of multimodal surgical AI systems and contribute to the development of next-generation foundation models for surgery. Dataset publicly available at https://huggingface.co/datasets/filbel/SurgAtlas

Fine-tuned encoders deployed across heterogeneous NLP tasks face three compounding problems: mismatched inductive biases, class-imbalance corruption of feature statistics, and no mechanism to condition attention on external lexical knowledge. We introduce \textbf{\surgellm}, a unified transformer framework that addresses each with a dedicated lightweight module: a \emph{surgical feature gate} (learned per-dimension sigmoid over curated lexical indicators and \texttt{[CLS]}; provably degenerates to identity when features are uninformative), \emph{task-conditioned prefix tokens} (quantized feature values and task identity prepended to every input), and \emph{Instance-Weighted Normalization} (IWN; removes class-prior bias from gate statistics). We prove an excess-risk bound linking gate benefit to \emph{surgical feature alignment}. Across four tasks, SST-2, multi-hop retrieval, LLM-prompt attribution, and authorship detection, covering 17,830 examples and eleven model variants over three seeds, the IWN variant achieves macro-F1 \textbf{0.940} ($+0.036$ over the strongest non-IWN baseline; $+0.130$ on authorship detection). A random-vocabulary control ($-0.028$ avg.\ F1) confirms gains are lexical, not parametric. Code, vocabularies, and a $99.5\%$-recovery auto-extraction recipe are released.

Robot-assisted minimally invasive surgery improves surgical precision but introduces complexity, making technical error detection essential for ensuring patient safety. Current executional error detection methods using video data often overlook fine-grained contextual descriptions of activities and error types within the hierarchical structure of surgical procedures. They also under-utilize complementary multimodal information. We propose a unified framework for executional error detection that leverages multimodal input, including video, kinematics, and descriptive textual prompts. Through activity prompting, we integrate descriptive language in gesture-level activities, instrument-object interactions, and error definitions. We also introduce activity-aware visual embeddings derived from vision encoders pretrained on surgical activity labels to compare the effectiveness of contrastive language-image embeddings with traditional image-based embeddings for error detection. By seamlessly integrating kinematic data with video and textual modalities, our framework significantly improves error detection performance. Achieving up to 5% and 16.6% F1 score improvements over state-of-the-art baselines on the JIGSAWS and SAR-RARP50 datasets, respectively, we demonstrate the value of combining curated textual prompts with multimodal data for accurate error detection.

Large language models (LLMs) achieve remarkable performance across a wide range of tasks, but their deployment is constrained by substantial memory and compute requirements. Low-rank compression via singular value decomposition (SVD) is an effective remedy, but existing methods focus on how to factorize and which components to keep. We introduce SVD-Surgeon, a training-free method that brings the Optimal Brain Surgeon (OBS) framework to the singular-value basis. Treating each singular value as a parameter, it computes a closed-form update of the retained singular values that compensates, to second order in the model loss, for those removed by truncation. The same analysis yields a saliency for choosing which values to prune. As it operates directly on the singular-value factorization, SVD-Surgeon can be layered on top of existing SVD compressors. Applied to SVD-LLM, a leading SVD-based method, it improves the perplexity-compression trade-off on the OPT family and LLaMA 2-7B without any retraining.

Intraoperative Adverse Events (IAEs) detection is critical for improving surgical safety, with bleeding being among the most frequent events across many surgery types. Existing methods struggle to distinguish bleeding IAE from visually similar residual blood due to limited temporal reasoning. Moreover, modeling long surgical videos while preserving fine-grained temporal dynamics remains computationally challenging. We propose DBT-Bleed, a dual-branch multi-scale temporal modeling framework disentangling bleeding and normal representations using layer-wise temporal adapters for short- and long-term bleeding progression. To efficiently process long surgical videos without sacrificing fine-grained temporal information, we introduce HiRED, a Hierarchical Entropy-Driven frame selection strategy that retains temporally informative segments while removing redundancy. Experiments on the MultiBypass dataset demonstrate gains of 6.53% in F1, 5.62% in Recall and 9% in MCC values for bleeding IAE detection, consistently outperforming video-level baselines. Additionally, we evaluate cross-procedure generalization on a newly curated dataset from a different surgical procedure type, where DBT-Bleed demonstrates robust transferability by achieving gain of 6% in F1 and 8% in MCC under zero-shot setting. To support this evaluation, we introduce EndoPit-IAE, an Endonasal Pituitary Surgery dataset annotated for IAEs, representing the first IAE-annotated dataset in neurosurgery. Code will be made publicly available upon acceptance.

Federated Learning (FL) in surgical video AI enables collaborative model training without sharing sensitive data. However, standard evaluation practices - selecting the "best" global model based only on validation data from participating hospitals - can lead to suboptimal deployment choices. We identify this critical failure mode as performance leakage, where the selected model overfits internal federation data and fails to generalize to unseen institutions. We propose GEN-Guard, a practical post-hoc framework to detect and correct generalization failures in federated surgical AI. It integrates Generalization Detection via Client-Blocked Evaluation (CBE), which validates performance on isolated client distributions to prevent performance leakage, and Generalization Correction through Disagreement-Aware Distillation (DAD), which learns adaptive feature-level corrections for cross-institutional robustness. Both components operate after standard FL convergence while providing robust support for zero-shot adaptation to unseen environments. We first quantify the severity of performance leakage, observing Model Selection Failures (MSFs) exceeding 80% under standard evaluation. GEN-Guard is evaluated on two multi-center clinical challenges: surgical phase recognition in laparoscopic cholecystectomy and polyp segmentation in colonoscopy. Across both datasets, GEN-Guard consistently corrects these failures, improving in-federation F1 scores by up to 2 points, unseen-institution performance by up to 3 points, and worst-case institutional performance by 3-9 points. Performance leakage represents a systematic and previously under-recognized risk in federated surgical AI. GEN-Guard provides a practical solution for detecting and correcting such failures. By improving cross-institutional robustness and zero-shot generalization, it strengthens the reliability of FL for real-world surgical deployment.

Scaling robot policy learning for autonomous surgery is challenging, as expert demonstrations are expensive and in vivo exploration poses substantial safety risks. Surgical world models address this by generating realistic, action-conditioned future frames from an initial observation, but existing methods exhibit two persistent failure modes: spatial interaction incoherence, where visible instrument contact fails to induce spatially consistent tissue deformation, and temporal fidelity collapse, where prediction errors compound across autoregressive rollouts and progressively corrupt visual quality. We present SurgVista, a surgical world model that mitigates both failures through two training recipes. Deformation Consistency Regularization extracts scene-point trajectories from training videos and enforces cross-frame coherence through latent contrastive learning, strengthening physically consistent instrument-tissue dynamics. Drift Adaptation Training mitigates long-horizon drift by perturbing conditioning frames with online prediction residuals and photometric augmentations calibrated to long-horizon drift statistics, sustaining visual fidelity over extended rollouts. To enable rigorous evaluation, we further introduce SurgWorld-Bench, featuring diverse procedure types, long-range rollouts, and decoupled metrics for instrument-motion accuracy and tissue-response fidelity. Extensive experiments show that SurgVista consistently outperforms state-of-the-art methods across visual quality, temporal consistency, and interaction fidelity, with gains widening as the prediction horizon grows.

With 890,000 annual new cases globally, head and neck squamous cell carcinoma has one of the highest recurrence rates among solid malignancies. Although frozen section analysis is the standard of care for intraoperative margin assessment, accurately relocating detected positive margins on the resection bed remains challenging due to imprecise alignment between resected specimens and their resection bed, compounded by post-resection mucosal tissue shrinkage. We present a biomechanics-driven deformable registration framework that corrects post-resection tissue deformation to provide intraoperative guidance. Our approach registers 3D specimen meshes to intraoperative resection bed point clouds using a deformable registration approach based on regularized Kelvinlet basis functions. The registration matches surface point clouds, fiducial landmarks, and boundary contour constraints that directly penalize perpendicular distance-to-agreement between specimen and resection bed boundaries. Across nine specimens from skin, buccal mucosa, and tongue sites, the overall mean target registration error was $11.11 \pm 4.07$ mm using rigid registration, which decreased to $8.20 \pm 2.68$ mm (26.19% reduction) using deformable registration without contour constraint. The proposed contour-constrained deformable registration further reduced the error to $5.62 \pm 2.28$ mm, a 49.41% reduction relative to rigid registration. We observed the largest reduction in the most clinically challenging tongue specimens. We also performed a systematic two-stage parameter search to characterize the relative importance of surface alignment, fiducial correspondences, contour constraint, and strain energy regularization. This search revealed that contour weighting dominates registration accuracy for tissue types with large lateral deformation, while the algorithm operates over a broad range of parameter combinations.

Continuum robots offer a promising approach for minimally invasive and natural-orifice surgical procedures due to their inherent compliance and dexterity. However, this flexibility also makes estimating the current shape of the robot challenging. Several approaches have been used to reconstruct the shape of these robots, including imaging, optical sensing, magnetic sensing, and resistive sensing. Strain sensors fabricated using direct laser writing (DLW) could provide an alternative sensing method. This technique involves using a laser to induce carbonization of certain polymers to create graphene patterns, such as strain sensors. In this paper, we demonstrate how a flexible continuum joint and a DLW sensor can be machined as one monolithic structure using the same laser and the same setup. The fabricated sensors are characterized using linear and nonlinear models, which are used to predict the joint angle with error as low as 1.76 degrees. Furthermore, we demonstrate how a DLW sensor can be used to implement closed-loop control in a robotic joint, achieving tracking error under 3 degrees.

Surgical outcomes depend not only on patient factors and postoperative care but are also strongly influenced by the quality of the operation itself. Yet, for much of mod-ern surgery, intraoperative quality has been assessed indirectly through outcomes and operative reports. The increase in minimally invasive procedures inherently guided by endoscopic video, together with advances in artificial intelligence, creates an unprecedented opportunity to systematically observe, measure, and improve surgi-cal care. This chapter introduces AI-enabled Surgical Quality Assurance as a frame-work for using surgical data to support continuous assessment and improvement in the operating room. We first review existing approaches to surgical safety, from sys-tem-level interventions to procedure-specific standards. We then describe how AI can transform intraoperative video into clinically meaningful information, including recog-nition of anatomy, instruments, workflow, surgical actions, quality criteria, adverse events, and critical moments. Finally, we outline the major challenges that must be addressed before these systems can deliver routine clinical value, including representa-tive data collection, robust validation, workflow integration, regulation, liability, pri-vacy, and equitable access. Rather than replacing surgical judgment, AI for quality assurance should be understood as a set of tools for augmenting the surgical team, scaling expert review, and helping surgery evolve toward a learning system in which intraoperative care is continuously observed, assessed, and improved.

Detecting anatomical structures in surgical video is essential for intraoperative safety frameworks such as the Critical View of Myopectineal Orifice (CVMPO) in inguinal hernia repair. While prominent structures like the Cooper's Ligament and Triangle of Doom are reliably detected by standard methods, smaller structures such as the epigastric vessels remain challenging due to their visual ambiguity and intermittent visibility. We observe that the spatial relationship between structures is anatomically constrained, and propose a Gaussian Spatial Prior (GSP) module that encodes this relationship as a compact, parametric bias injected into the self-attention of a DAB-DETR decoder. The prior is computed offline from training annotations as a small set of frozen Gaussian parameters and recomputed at each decoder layer using the iteratively refined reference points. On a dataset of inguinal hernia repair videos with 5-fold cross-validation, GSP improves dependent class detection by $+33.5\%$ ($\text{AP}_{50}$) over DAB-DETR and $+53.9\%$ over YOLOv26, while also improving anchor detection by $+6.0\%$. These gains are statistically significant across all folds ($p=0.012$, paired $t-$test).

Partial-to-full registration remains challenging due to varying overlap ratios, fluctuating point densities, and the presence of noise. While transformers have shown strong potential for point cloud processing, prior methods typically confine them to global context aggregation, overlooking fine-grained local geometry crucial for accurate correspondence. We propose \emph{GAPR-Net}, a learning-based point cloud registration framework with a coarse-to-fine architecture that combines convolution and transformer modules, in which local and global information is fused between the partial and full point clouds using a cross-attention mechanism. To achieve this, a transformation-invariant point-wise geometric feature representation is proposed, which can robustly capture relative geometric features for individual points with respect to their neighboring points. To evaluate the effectiveness of the proposed approach, experiments are conducted on four geometrically distinct bones, including the tibia, femur, pelvis, and thoracic cartilage. The overall registration recall reaches 94.2%, the method results in a low RMSE of 1.992 mm and $R^2$ values of 0.908 and 0.974 for rotation and translation, respectively. The results demonstrate that the proposed method effectively addresses the partial-to-full point cloud registration problem. The proposed method enables highly accurate 3D point cloud registration using partial observation, providing a critical foundation for precise surgical navigation and robotic interventions in computer-assisted surgery. The code will be accessed after the double-blind review process.

As deep learning models scale, managing, inspecting, and modifying large checkpoints has become increasingly challenging. Researchers often need to alter model weights for layer restructuring, precision casting, low-rank factorization, and architectural debugging, yet these workflows often rely on fragile ad-hoc Python scripts. Here, we introduce BrainSurgery, a tool for robust and reproducible "tensor surgery" on neural network checkpoints, and provide a system demonstration covering four examples and three case studies from model upcycling to LoRA extraction. By abstracting storage formats and memory management, BrainSurgery executes complex transformations through declarative YAML plans. It supports structural modifications, mathematical transformations, and tensor reshaping through expressive regex and structural targeting, while built-in assertions validate tensor shapes, data types, and values to prevent silent errors. We envision that BrainSurgery will provide a strong foundation for future research through its reproducible and validated operations.

Recently, mobile edge computing (MEC)-enabled collaborative deep neural network (DNN) inference has emerged as a promising approach for delivering intelligent services to resource-constrained mobile devices. A representative scenario is multi-user collaborative edge inference, where distinct devices independently partition their DNN models and offload backend computation to a common edge server over wireless networks. However, determining the optimal DNN partition for each device is challenging due to unknown and time-varying system conditions, including fluctuating wireless links and diverse device capabilities. To address this problem, we propose Cooperative Autodidactic NeuroSurgeon (CANS), a collaborative edge inference framework that enables devices to adaptively learn optimal DNN partitions by sharing informative feedback during online inference. To handle the challenge of device heterogeneity and better leverage offline inference experience, we integrate a novel FedLinUCB-DW algorithm that groups devices of the same type and warm-starts online exploration using local offline early-exit inference experience. Furthermore, we provide theoretical guarantees for FedLinUCB-DW by deriving the regret upper bound. We also validate our method on both a simulated environment and a hardware prototype system. Empirical evaluations demonstrate that CANS achieves lower inference latency compared to state-of-the-art baselines. Especially, in prototype experiments on two edge devices, the proposed CANS reduced average inference latency by up to 50% compared to the non-cooperative baseline.

Reliable evaluation of large language models in surgery remains underdeveloped. Broad medical benchmarks test clinical knowledge, while surgery requires procedural reasoning, management trade-offs, negation handling, and selection among plausible operative decisions. We present SurgiQ, a text-only, source-grounded benchmark of 13,055 four-option multiple-choice questions spanning six surgical domains and four question formats: case-based, reasoning, best-option, and negative. SurgiQ is constructed from surgical textbooks, open-access papers, and examination material using a multi-stage generation, verification, and expert-audit pipeline. We evaluate 35 open-weight LLMs under a unified log-likelihood protocol. Our results show substantial remaining headroom: smaller models often remain near the 25% random baseline, while the best model reaches 68.1% accuracy. General-purpose models, especially Qwen2.5, outperform most biomedical models, suggesting that current medical specialization does not yet provide sufficiently broad surgical coverage. Calibration and error analysis further show that even strong models make confident mistakes on clinically plausible distractors, motivating more reliable and broader surgical LLM evaluation.

The handling and assembly of instruments during surgery imposes high cognitive demands on scrub nurses, particularly when instruments are unfamiliar. We present a supporting guidance system for surgical instrumentation that combines multi-camera 6D pose estimation with augmented reality in-situ visualization on a head-mounted display without the requirement for additional markers. Pose estimation and consecutive camera calibration are achieved through known objects. The 6D pose estimation network is trained purely on synthetic data, aiming for better generalizability and real-world applicability. The AR guidance displays tooltip localization cues and step-wise assembly animations. Via gaze-based selection and a foot pedal, users can switch between assembly steps in intraoperative use. In a technical evaluation, our approach outperforms state-of-art 6D pose estimation. A user study with 29 scrub nurses was conducted in a surgical simulation of knee arthroplasty, comparing the system against a paper manual. AR guidance significantly reduced the perceived workload compared. Objectively, AR guidance reduced task completion time by 21.3% (4.76 minutes). Specifically, scrub nurses less experienced with the instrument set benefited when using the system. Error frequencies were comparable between conditions. Qualitative feedback highlighted improved process clarity, reduced information overload, and perceived independence. To summarize, our marker-free multi-camera AR guidance approach for surgical instruments can, subjectively and objectively, improve intraoperative instrumentation performance, particularly for untrained scrub nurses.

Maximal safe resection is the primary objective in glioma surgery. Neuronavigation guidance is progressively degraded by brain shift after dural opening. Intraoperative MRI can compensate but needs dedicated infrastructure and is rarely available, whereas intraoperative ultrasound (ioUS) is inexpensive, repeatable, and compatible with routine workflows. Navigation systems combining ioUS with preoperative MRI usually rely on rigid registration; even deformable multimodal registration is limited by ultrasound speckle contrast, a narrow field of view, and the inability to represent structures absent from the preoperative scan, most critically the resection cavity and residual tumor. We propose an end-to-end pipeline that generates a new whole-brain MRI volume in the preoperative imaging space by merging the preoperative MRI, a synthetic MRI generated from the ioUS, and a deformable registration anchored on that synthetic image. It integrates a 2.5D residual-transformer synthesis backbone (ResViT-2.5D) and a two-stage registration coupling NiftyReg with a synthesis-anchored SynthMorph stage, operating directly on raw scanner inputs. On a post-resection ReMIND cohort, ResViT-2.5D produced synthetic images closely matching the intraoperative T2 across structural, intensity, and perceptual metrics. In 14 subjects with 215 expert landmarks, the synthesis-anchored registration reduced the mean target registration error from 6.27 to 5.86 mm, matching a strong classical NiftyReg baseline (5.85 mm) while yielding a diffeomorphic deformation field in every subject. The contribution is not a gain in registration accuracy but the integrated volume itself, which inside the ultrasound field of view it reflects the intraoperative post-resection state. This provides the surgeon with an MRI-like update of the operative field with potential for integration into surgical-navigation workflows.

Anastomotic leak remains one of the most serious complications following colorectal cancer surgery, substantially affecting patient outcomes, recovery trajectories, and healthcare costs. Despite advances in imaging technology, current preoperative assessment relies only on clinical assessment, a process that is subjective, error-prone, and highly dependent on individual expertise. To date, no validated CT-based method exists to predict anastomotic leak risk prior to surgery. This protocol paper outlines a comprehensive framework for developing and validating an AI-driven system for preoperative risk assessment using pre- and post-contrast CT imaging. The study describes the stages of data collection, ethical handling, and preprocessing of patient data in accordance with GDPR, image preprocessing, and the exploration of deep learning architectures designed to generate clinically interpretable outputs. Two integrated tools constitute the main deliverables of this workflow: 1) a risk assessment module, which quantifies the likelihood of leakage by analyzing vascular and tissue features in CT scans, and 2) a Content-Based Medical Image Retrieval (CBMIR) module, which identifies and displays similar historical cases to support evidence-based surgical decision making. The protocol paper requires close collaboration between hospitals and universities; this protocol demonstrates that such a system is technically feasible and clinically implementable within existing healthcare infrastructures. By following the proposed methodological stages and regulatory principles, other institutions can reproduce this workflow to develop analogous decision-support tools. Ultimately, this interdisciplinary framework aims to enhance surgical planning, reduce leak incidence, and contribute to a broader paradigm shift toward explainable, data-driven precision surgery.

Robot-Assisted Minimally Invasive Surgery (RAMIS) enhances surgeon dexterity, with newer platforms leveraging haptic feedback to further improve performance. Such force information has broader potential to inform performance assessment, tactile localization, and surgical autonomy. This motivates the need for accessible approaches to integrating force sensing into RAMIS tools. This work presents a method for integrating a six-axis commercial force sensor into the distal end of a standard cable-driven surgical instrument, enabling end-effector force measurement while preserving the original mechanical functionality of the device. The proposed design emphasizes reproducibility and accessibility for research applications, requiring no specialized manufacturing tools. A transformer neural network integrates force sensor measurements with robot state information to aid estimation of applied forces at the end-effector, compensating for internal cable forces arising from actuation. Our proposed approach achieved normalized errors below 6%, and generalized to unseen conditions better than purely proximal data-driven sensing approaches. High internal cable forces caused sensor saturation and reduced axial force observability, which can degrade performance along the tool's major axis and under higher load conditions. Given current levels of performance, the balance of system integrability and performance enables applications and research into timely topics of haptic feedback, skill assessment, and force-informed autonomy in RAMIS. Videos and code are available at https://enhanced-telerobotics.github.io/shaft_force_sensing/.

Purpose: Laparoscopic ultrasound (LUS) enhances the safety of liver surgery by visualizing intrahepatic vessels in real-time. Still, vessel identification remains difficult due to probe constraints, complex vascular structure, and tissue deformation. This work aims to enable real-time, patient-specific vessel identification that remains robust under deformation through deformable ultrasound augmentation. Methods: Preoperative CT vessel annotations are used to generate synthetic ultrasound data via optimized physics-based rendering, coupled with domain adaptation to intraoperative ultrasound. The rendering is trained end-to-end for vessel identification and patient-specificity, eliminating the need for preoperative ultrasound. A deformation-aware augmentation simulates realistic intraoperative motion and tissue deformation within the rendering pipeline. Results: In abdominal phantom and limited clinical feasibility experiments (single-case clinical evaluation), the framework achieved real-time intrahepatic vessel-branch identification, maintaining performance under new patient poses. Conclusion: The framework enables real-time vessel identification without preoperative ultrasound and supports technical feasibility, but multi-patient validation is still needed for generalizability and clinical feasibility.

This study presents the first evaluation of general-purpose imitation learning for surgeon-robot collaborative assistance in open surgery, targeting suture following: the grab-pull-release motion an assistant performs at every stitch. We collect 160 teleoperated demonstrations (32,374 frames) on an open-source robot arm, benchmark four architecturally diverse imitation learning policies (ACT, Diffusion Policy, SmolVLA, $π_0$) across 28 trained models evaluated in 32 configurations along three clinically motivated dimensions: dataset size, camera viewpoint, and background variation. Our results demonstrate that under ideal conditions, the four policies achieve $50$-$75\%$ task success, with depth error as the dominant failure mode across all architectures. Among all policies, $π_0$ achieves the strongest results with a pretrained vision-language backbone, demonstrating superior data efficiency, greater robustness to background variation, and smoother trajectories compatible with surgical workflow. When deployed in a surgeon-robot suturing trial, $π_0$ yields a $92\%$ stitch completion rate. These findings establish collaborative robotic assistance in open surgery as a feasible target for imitation learning and highlight depth perception and end-effector design as key priorities for clinical translation.

Liver surface landmark detection is a fundamental prerequisite for anatomical guidance in laparoscopic liver surgery. However, it remains unreliable in practice due to two pervasive challenges: illumination attenuation in underexposed regions and the structural mismatch between pixel-wise localization and continuous curvilinear geometry. To address these limitations, we propose A2ONet, an attenuation-resilient alternating optimization network for robust liver landmark detection. To mitigate illumination attenuation, A2ONet embraces an illumination field compensation (IFC) block that adaptively enhances dark regions while preserving structural consistency. Meanwhile, we introduce a lightweight frequency-orientation selective filter (FOSF) to suppress repetitive texture interference and preserve salient curvilinear cues. Building upon these resilient representations, we design an alternating seg-curve optimization (ASCO) decoder that iteratively couples dense segmentation with explicit curve modeling, enabling mutual guidance to optimize both structural continuity and endpoint localization. Extensive evaluations on L3D-2K, L3D, and P2ILF demonstrate consistent improvements over competitive methods, establishing a more reliable foundation for intraoperative anatomy guidance. Our code will be available at https://github.com/hyperiondk115/A2ONet.

Surgical instrument pose estimation provides crucial information for promising applications, including autonomous robotic surgery, skill assessment, and standardization of surgical workflow. However, this task remains highly challenging due to high precision requirements, frequent occlusions, textureless instruments, scarcity of depth information and very limited annotated data. These constraints often lead to unsatisfactory performance when employing general object pose estimation approaches to surgical scenarios. To address these issues, we first construct a new dataset SynSurg6D, to alleviate the data shortage in this task. We further propose SurfSurg6D, a dense-correspondence framework tailored for surgical instrument pose estimation. Experimental results on the SurgRIPE, EndoVis2018 and SurgPose datasets demonstrate that the introduction of our generated dataset SynSurg6D is able to diversify the pose distributions, thus enhancing the performance of existing approaches. Furthermore, SurfSurg6D outperforms existing methods, providing a robust solution for precise and efficient RGB-only pose estimation.

Verbal feedback delivered by attending surgeons in the operating room plays a critical formative role in resident trainee skill acquisition. Yet, assessing the quality of trainer feedback and its effectiveness in influencing trainee behavior during live surgery remains a challenge. Prior studies assessed feedback content relying on extensive manual annotation by expert human raters and focused on developing broad taxonomies that overlook the qualitative aspects of feedback delivery such as clarity or urgency. Limited existing automated methods, including keyword analysis and topic modeling, also fail to capture these nuanced aspects. We introduce a two-stage LLM-based framework that discovers interpretable feedback quality criteria grounded in the context of surgical training. Our method uses multi-agent prompting and surgical domain knowledge injection to discover a small set of human interpretable scoring criteria (e.g., Encouraging, Urgent, Clear). These criteria are then used to automatically score live surgical feedback via an LLM-as-a-judge approach. Evaluation on 4.2k trainer feedback instances demonstrates that our AI-discovered criteria outperform prior content-based frameworks in predicting feedback effectiveness, including observed trainee behavioral adjustments and trainer approval. This work advances scalable, human-aligned assessment of communication quality in the operating room and provides a foundation for improving surgical teaching practices.

We present a kinematic and transmission-aware design framework for a serial spherical mechanism with an additional translational degree of freedom for microsurgery. The first contribution is an analytical workspace formulation that provides geometric insight into reachable motion and enables rapid selection of rotation axis orientations without numerical optimization. The second contribution is a dynamics-informed methodology for mechanisms driven by self-locking transmissions, supporting evaluation of torque requirements for a prescribed workspace geometry. The framework is accompanied by an open-source software package for friction identification and inverse dynamics analysis. Experiments on a purpose-built robotic tool for vitreoretinal surgery validate the predictive capability of the models and demonstrate their practical utility for engineering design.

Timely and transparent feedback is essential for effective surgical training, yet current assessment remains dependent on expert observation, limiting scalability and opportunities for autonomous practice. We present ExpOS, an explainable framework for data-driven assessment of open-surgery skills designed to enable automatic, feedback-oriented evaluation. Rather than relying on expert-defined metrics, ExpOS learns discriminative temporal patterns directly from motion data and identifies the segments and behaviors most predictive of skill level. We trained and evaluated the method on 221 videos of medical students performing three open-surgery tasks. Hand poses and tool detections were extracted from each frame to derive kinematic descriptors and global motion statistics. Spatiotemporal hand-tool dynamics were modeled using a temporal convolutional backbone with attention-based pooling to generate frame-level importance maps. These representations were fused with global motion statistics to predict skill level and to provide interpretable feedback. ExpOS provides multi-level explainability by identifying when informative events occur through attention weights and which motion characteristics most influence predictions through global feature analysis. Across tasks, the framework achieved strong correlation with expert ratings, with best performance on fascial closure (r = 0.778, R2 = 0.74). These results demonstrate that combining weakly-supervised temporal importance learning with interpretable motion statistics enables scalable and actionable surgical skill assessment.

Reliable visual understanding in robot-assisted and minimally invasive surgery (RMIS/MIS) demands more than accurate masks: in clinical practice, clinicians pose language-like questions about procedural context, visibility, artefacts, and the presence of anatomical structures and surgical instruments, often under degraded views caused by occlusion, smoke, bleeding, and specular highlights. We present \textbf{RoboSurg-VQA}, a segmentation-aware visual question answering (VQA) benchmark built by repurposing public surgical segmentation datasets under a shared schema. Each frame is paired with a fixed set of clinically motivated questions spanning procedure context, anatomy (including region), imaging modality/view, surgical artefacts, image quality, and basic visibility and spatial attributes, with closed answer sets to enable consistent evaluation. To scale annotation, we generate candidate answers via constrained prompting with automatic validity and consistency checks, followed by human auditing to improve plausibility and label consistency. We report benchmark statistics, sanity baselines, and common evaluation challenges under challenging surgical conditions. The code will be available on https://github.com/ziyangwang007/Robosurg-VQA.

Reasoning capability has significantly advanced complex logical inference and robotic decision-making in general domains. However, its potential in the Artificial Intelligence (AI) copilot robot-particularly implemented based on the Vision-Language-Action (VLA) model-remains unexplored in endoscopic surgery. Effective reasoning should enable AI copilot robots to integrate multimodal cues, interpret surgical intent, and infer hidden tissue dynamics, thereby alleviating intraoperative uncertainty and cognitive burden on surgeons. Properly implemented, reasoning-driven autonomy can transform AI copilot robots from reactive executors into cognitive collaborators, enhancing precision, safety, and sustainability in clinical practice.

Achieving high levels of surgical skill through effective training is essential for optimal patient outcomes. Automated, data-driven skill assessment holds significant potential to improve surgical training. While machine learning-based methods are increasingly popular for assessing skills in minimally invasive surgery, their application to open surgery remains limited. We present the results of a dedicated MICCAI challenge designed to benchmark and advance vision-based skill assessment in open surgery. The challenge dataset comprises videos of an open suturing training task recorded with a static GoPro camera in a dry-lab setting, with instrument trajectories available in addition to the primary video modality. The OSS Challenge was hosted over two consecutive years, comprising two and three independent tasks, respectively: (1) classifying skill level into four classes, (2) predicting the full Objective Structured Assessment of Technical Skills across eight categories, and (3) tracking hands and surgical tools. Participants submitted diverse solutions including deep learning-based video models, tracking-driven methods, and hybrid approaches. General-purpose spatiotemporal video models consistently achieved the strongest performance, though conceptually diverse approaches reached competitive levels when well-executed. Predicting fine-grained OSATS scores remains challenging but benefits substantially from increased training data. Keypoint tracking proves difficult given frequent occlusions and out-of-frame instances, limiting current applicability for motion-based skill analysis. This work benchmarks innovative and diverse solutions for surgical skill assessment, highlighting both the promise and current limitations of video-based evaluation in open surgery and identifying critical directions for advancing automated skill assessment toward clinical impact.

Surgical Video Question Answering (VideoQA) provides a promising paradigm for dynamic intraoperative interpretation, enabling real-time decision support and context-aware retrieval in clinical environments. Nevertheless, existing approaches are predominantly restricted to images or short clips, limiting their ability to model long-range procedural dynamics and causal dependencies across extended surgical workflows. To address this challenge, we propose SurgLQA, a unified long-horizon VideoQA framework for scalable surgical reasoning. This framework incorporates Faithful Temporal Consolidation (FTC), which leverages intrinsic temporal cues to construct compact long-range representations while preserving fine-grained temporal fidelity. Further, we develop Temporally-Grounded Multi-Policy Scaling (TMS), an adaptive test-time inference paradigm that strategically adjusts policy-level reasoning capacity within temporally grounded contexts. To facilitate systematic evaluation, we restructured a long-duration colonoscopy VideoQA benchmark, Colon-LQA, and conducted extensive experiments on Colon-LQA and REAL-Colon-VQA. Experimental results demonstrate that our approach achieves consistent performance gains in long-range reasoning with temporally grounded inference. Code link: https://github.com/RascalGdd/SurgLQA.

Surgical scene understanding is a cornerstone of computer-assisted intervention. While recent advances, particularly in surgical image segmentation, have driven progress, real-world clinical applications require a more holistic understanding that jointly captures procedural context, semantic reasoning, and precise visual grounding. However, existing approaches typically address these components in isolation, leading to fragmented representations and limited semantic consistency. To address this limitation, we propose SurgMLLM, a unified surgical scene understanding framework that bridges high-level reasoning and low-level visual grounding within a single model. Given surgical videos, SurgMLLM fine-tunes a multimodal large language model (MLLM) to support structured interpretability reasoning, which is used to jointly model phases, instrument-verb-target (IVT) triplets, and triplet-entity segmentation tokens. These tokens are then temporally aggregated and serve as prompts for a segmentation network, enabling accurate pixel-wise grounding of triplet instruments and targets. The entire framework is trained end-to-end with a unified objective that couples language-based reasoning supervision with visual grounding losses, promoting coherent cross-task learning and clinically consistent scene representations. To facilitate unified evaluation, we introduce CholecT45-Scene, extending CholecT45 dataset with 64,299 frames of pixel-level mask annotations for instruments and targets, aligned with existing triplet labels. Extensive experiments show that SurgMLLM significantly advances surgical scene understanding, improving the primary triplet recognition metric AP_IVT from 40.7% to 46.0% and consistently outperforming prior methods in phase recognition and segmentation. These results highlight the effectiveness of unified reasoning-and-grounding for reliable, context-aware surgical assistance.

LoRA is widely adopted for continual fine-tuning of Large Language Models due to its parameter efficiency, modularity across tasks, and compatibility with replay strategies. However, LoRA-based continual learning remains vulnerable to catastrophic forgetting, whose severity depends on how successive task gradients interact: when consecutive task gradients conflict, standard adapter initializations channel updates into subspaces that overwrite previously learned directions. We propose SLICE, a gradient-surgery-based initialization for LoRA adapters in continual learning. SLICE accumulates gradients from both the current task and a replay buffer of prior tasks, reconciles them through a projection operator, and decomposes the result via truncated SVD to initialize the adapter weights. We evaluate SLICE on the TRACE benchmark and sequences of Super-NI tasks, including a set of adversarial Super-NI sequences that we construct by mining task pairs with maximally opposing gradients. Compared to vanilla LoRA, LoRA-GA, and LoRAM, SLICE consistently achieves a better stability-plasticity trade-off, improving Average Performance, Final Performance and Forgetting metrics while preserving General Performance and In Context Performance across both standard and adversarial continual learning sequences.